Rattus norvegicus

0 known processes

Prg4

proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)

Prg4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.056
programmed cell deathGO:00125013920.056
regulation of protein metabolic processGO:00512462890.054
oxoacid metabolic processGO:00434362900.052
response to inorganic substanceGO:00100353770.051
organic acid metabolic processGO:00060822920.050
protein phosphorylationGO:00064683450.049
carbohydrate derivative metabolic processGO:19011353460.047
regulation of transcription dna templatedGO:00063553740.045
rna metabolic processGO:00160704060.044
catabolic processGO:00090563510.043
regulation of phosphorus metabolic processGO:00511743490.043
intracellular signal transductionGO:00355563140.042
secretionGO:00469033070.042
response to extracellular stimulusGO:00099913800.042
regulation of molecular functionGO:00650093980.042
response to nutrient levelsGO:00316673700.042
cellular ketone metabolic processGO:0042180510.041
regulation of apoptotic processGO:00429813350.040
regulation of phosphate metabolic processGO:00192203490.040
apoptotic processGO:00069153810.039
negative regulation of metabolic processGO:00098923310.038
positive regulation of nitrogen compound metabolic processGO:00511733340.038
regulation of cell differentiationGO:00455953200.037
transcription dna templatedGO:00063513770.037
central nervous system developmentGO:00074173110.037
regulation of rna metabolic processGO:00512523910.037
regulation of programmed cell deathGO:00430673410.037
response to peptideGO:19016522920.037
homeostatic processGO:00425923310.037
regulation of rna biosynthetic processGO:20011413810.036
regulation of catalytic activityGO:00507903040.036
regulation of cellular ketone metabolic processGO:0010565270.036
positive regulation of phosphate metabolic processGO:00459372620.035
anatomical structure morphogenesisGO:00096532980.035
single organism biosynthetic processGO:00447113420.035
cellular component assemblyGO:00226073600.035
positive regulation of multicellular organismal processGO:00512403870.034
positive regulation of transportGO:00510502450.034
cellular amino acid metabolic processGO:00065201070.034
regulation of cellular protein metabolic processGO:00322682670.033
amine metabolic processGO:0009308380.033
positive regulation of phosphorus metabolic processGO:00105622620.033
positive regulation of signalingGO:00230562700.033
rna biosynthetic processGO:00327743800.033
locomotionGO:00400112370.032
regulation of multicellular organismal developmentGO:20000263760.032
negative regulation of cellular metabolic processGO:00313242810.032
secretion by cellGO:00329402480.032
response to peptide hormoneGO:00434342780.032
cellular amine metabolic processGO:0044106380.032
positive regulation of response to stimulusGO:00485842850.031
organic substance catabolic processGO:19015753160.031
cellular response to oxygen containing compoundGO:19017013860.031
cell cell signalingGO:00072673350.031
regulation of cellular amino acid metabolic processGO:000652120.031
regulation of cellular amine metabolic processGO:003323880.031
regulation of cellular component organizationGO:00511283680.031
regulation of cell proliferationGO:00421273590.030
positive regulation of cell proliferationGO:00082842490.030
response to metal ionGO:00100382530.030
positive regulation of catalytic activityGO:00430851840.030
cellular component biogenesisGO:00440853680.030
regulation of intracellular signal transductionGO:19025312180.030
positive regulation of protein metabolic processGO:00512471780.030
cation transportGO:00068123820.030
regulation of cellular localizationGO:00603412630.030
nucleobase containing small molecule metabolic processGO:00550863160.029
positive regulation of molecular functionGO:00440932300.029
regulation of nucleic acid templated transcriptionGO:19035063800.029
organophosphate metabolic processGO:00196373700.029
regulation of cell developmentGO:00602842630.028
purine containing compound metabolic processGO:00725212530.028
negative regulation of macromolecule metabolic processGO:00106052600.028
nucleic acid templated transcriptionGO:00976593790.028
cellular response to endogenous stimulusGO:00714953770.028
single organism catabolic processGO:00447122830.028
cellular response to stressGO:00335542690.028
regulation of neurogenesisGO:00507672470.028
positive regulation of biosynthetic processGO:00098913190.028
neuron developmentGO:00486662860.027
chemical homeostasisGO:00488782920.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
nucleoside phosphate metabolic processGO:00067532830.027
regulation of protein modification processGO:00313991940.027
protein complex subunit organizationGO:00718223020.027
positive regulation of phosphorylationGO:00423271770.027
cellular catabolic processGO:00442482950.027
regulation of nervous system developmentGO:00519602640.026
reproductive processGO:00224143720.026
cellular component movementGO:00069282480.026
cell projection organizationGO:00300303020.026
regulation of phosphorylationGO:00423252480.026
cell migrationGO:00164771970.026
organelle organizationGO:00069962660.026
regulation of secretion by cellGO:19035302080.026
negative regulation of cell deathGO:00605482290.026
cellular chemical homeostasisGO:00550822470.026
localization of cellGO:00516742020.026
neuron differentiationGO:00301823680.026
nucleotide metabolic processGO:00091172790.026
regulation of signal transductionGO:00099663180.026
response to oxidative stressGO:00069791860.026
neuron projection developmentGO:00311752730.025
cellular homeostasisGO:00197252520.025
response to woundingGO:00096112540.025
brain developmentGO:00074202470.025
transmembrane transportGO:00550854120.025
macromolecule localizationGO:00330362520.025
glycosyl compound metabolic processGO:19016571820.025
positive regulation of cellular biosynthetic processGO:00313282950.025
aromatic compound catabolic processGO:00194391680.025
regulation of secretionGO:00510462240.025
protein complex assemblyGO:00064612630.025
macromolecular complex assemblyGO:00650032730.025
negative regulation of response to stimulusGO:00485851550.025
negative regulation of gene expressionGO:00106291990.024
regulation of protein phosphorylationGO:00019321830.024
cellular response to nitrogen compoundGO:19016992100.024
regulation of response to stressGO:00801341260.024
positive regulation of cellular protein metabolic processGO:00322701670.024
macromolecular complex subunit organizationGO:00439333390.024
positive regulation of gene expressionGO:00106282440.024
positive regulation of developmental processGO:00510942830.024
positive regulation of cellular amine metabolic processGO:003324030.024
positive regulation of cellular component organizationGO:00511302000.024
metal ion transportGO:00300012890.023
response to growth factorGO:00708481890.023
regulation of locomotionGO:00400121480.023
positive regulation of cell differentiationGO:00455972170.023
nitrogen compound transportGO:00717052290.023
purine nucleoside metabolic processGO:00422781690.023
g protein coupled receptor signaling pathwayGO:00071862420.023
protein oligomerizationGO:00512591910.023
multi organism reproductive processGO:00447032620.023
negative regulation of cellular biosynthetic processGO:00313271610.023
positive regulation of cell deathGO:00109421840.023
ribonucleoside metabolic processGO:00091191740.023
cellular response to hormone stimulusGO:00328702470.023
positive regulation of cellular amino acid metabolic processGO:004576410.022
cellular metal ion homeostasisGO:00068751720.022
positive regulation of protein phosphorylationGO:00019341350.022
response to nutrientGO:00075842480.022
positive regulation of cell communicationGO:00106472710.022
lipid metabolic processGO:00066292830.022
ion homeostasisGO:00508012120.022
negative regulation of apoptotic processGO:00430661810.022
protein complex biogenesisGO:00702712630.022
ribose phosphate metabolic processGO:00196932350.022
response to acid chemicalGO:00011012220.022
ribonucleotide metabolic processGO:00092592310.022
positive regulation of apoptotic processGO:00430651540.022
negative regulation of multicellular organismal processGO:00512412030.021
negative regulation of programmed cell deathGO:00430691830.021
response to carbohydrateGO:00097431830.021
purine nucleotide metabolic processGO:00061632290.021
positive regulation of nervous system developmentGO:00519621780.021
regulation of system processGO:00440572080.021
positive regulation of cell developmentGO:00107201760.021
reproductionGO:00000032450.021
positive regulation of rna biosynthetic processGO:19026801970.021
defense responseGO:00069521940.021
head developmentGO:00603222470.021
cellular ion homeostasisGO:00068731840.021
circulatory system developmentGO:00723591340.021
neurological system processGO:00508772190.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
wound healingGO:00420601220.020
signal releaseGO:00230611450.020
cell motilityGO:00488702020.020
single organism reproductive processGO:00447022970.020
regulation of transferase activityGO:00513381230.020
ras protein signal transductionGO:0007265290.020
regulation of hydrolase activityGO:00513361430.020
regenerationGO:00310991630.020
positive regulation of protein modification processGO:00314011420.020
multicellular organismal reproductive processGO:00486092330.020
carbohydrate derivative catabolic processGO:19011361470.020
agingGO:00075682410.020
metal ion homeostasisGO:00550651860.020
negative regulation of cell communicationGO:00106481580.019
negative regulation of signalingGO:00230571570.019
nucleoside metabolic processGO:00091161790.019
protein localizationGO:00081041910.019
response to biotic stimulusGO:00096072260.019
tissue developmentGO:00098882520.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
divalent inorganic cation homeostasisGO:00725071650.019
cellular response to organonitrogen compoundGO:00714171970.019
cellular response to organic cyclic compoundGO:00714072020.019
response to estrogenGO:00436272320.019
organic cyclic compound catabolic processGO:19013611750.019
cellular nitrogen compound catabolic processGO:00442701630.019
response to oxygen levelsGO:00704822650.019
immune system processGO:00023762040.019
positive regulation of transcription dna templatedGO:00458931970.019
response to hexoseGO:00097461440.019
cellular response to lipidGO:00713962010.019
heterocycle catabolic processGO:00467001670.019
purine ribonucleoside metabolic processGO:00461281680.019
biological adhesionGO:00226101100.019
regulation of cellular component movementGO:00512701500.019
intracellular transportGO:00469071850.019
negative regulation of biosynthetic processGO:00098901680.019
organonitrogen compound biosynthetic processGO:19015661670.019
transcription from rna polymerase ii promoterGO:00063662520.019
positive regulation of programmed cell deathGO:00430681570.018
regulation of ion transportGO:00432692450.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
regulation of membrane potentialGO:00423911100.018
heart morphogenesisGO:000300730.018
response to cytokineGO:00340972150.018
positive regulation of secretionGO:00510471400.018
positive regulation of neurogenesisGO:00507691650.018
negative regulation of developmental processGO:00510931250.018
positive regulation of secretion by cellGO:19035321280.018
leukocyte activationGO:0045321760.018
regulation of cell migrationGO:00303341280.018
positive regulation of locomotionGO:00400171020.018
small gtpase mediated signal transductionGO:0007264360.018
cell adhesionGO:00071551100.018
cellular cation homeostasisGO:00300031800.018
cardiovascular system developmentGO:00723581340.017
regulation of neuron differentiationGO:00456642080.017
cellular calcium ion homeostasisGO:00068741600.017
blood circulationGO:00080151830.017
proteolysisGO:00065081750.017
ion transmembrane transportGO:00342203650.017
negative regulation of protein metabolic processGO:00512481140.017
response to corticosteroidGO:00319602350.017
response to ethanolGO:00454711620.017
regulation of kinase activityGO:00435491170.017
inflammatory responseGO:00069541500.017
response to glucocorticoidGO:00513842230.017
ribonucleotide catabolic processGO:00092611360.017
positive regulation of ion transportGO:0043270940.017
response to external biotic stimulusGO:00432072210.017
single organism intracellular transportGO:19025821660.017
signal transduction by phosphorylationGO:00230141440.017
organonitrogen compound catabolic processGO:19015651790.017
nucleobase containing compound catabolic processGO:00346551520.017
regulation of hormone levelsGO:00108171870.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
lipid biosynthetic processGO:00086101280.017
response to organophosphorusGO:00466831020.017
cation homeostasisGO:00550801950.017
purine ribonucleotide metabolic processGO:00091502270.016
cellular response to growth factor stimulusGO:00713631620.016
cellular response to peptide hormone stimulusGO:00713751200.016
regulation of immune system processGO:00026821230.016
calcium ion homeostasisGO:00550741620.016
cellular response to peptideGO:19016531330.016
response to bacteriumGO:00096172000.016
regulation of metal ion transportGO:00109591180.016
response to purine containing compoundGO:00140741260.016
regulation of purine nucleotide metabolic processGO:19005421150.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
response to hypoxiaGO:00016662310.016
response to glucoseGO:00097491360.016
purine containing compound catabolic processGO:00725231380.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
divalent metal ion transportGO:00708381320.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
cellular component morphogenesisGO:00329891550.016
carbohydrate derivative biosynthetic processGO:19011371240.016
cell activationGO:0001775970.016
response to decreased oxygen levelsGO:00362932370.016
purine ribonucleotide catabolic processGO:00091541360.016
negative regulation of molecular functionGO:00440921330.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
eye morphogenesisGO:004859240.016
response to insulinGO:00328681330.016
nucleoside triphosphate metabolic processGO:00091411440.016
immune responseGO:00069551040.016
oxidation reduction processGO:00551143040.015
peptidyl amino acid modificationGO:00181931260.015
cellular response to external stimulusGO:00714961180.015
regulation of cell projection organizationGO:00313441750.015
negative regulation of transportGO:00510511360.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
positive regulation of intracellular signal transductionGO:19025331380.015
multicellular organism reproductionGO:00325042330.015
cell morphogenesis involved in differentiationGO:00009041190.015
response to monosaccharideGO:00342841590.015
positive regulation of hydrolase activityGO:0051345860.015
negative regulation of cellular protein metabolic processGO:00322691060.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
anterior posterior pattern specificationGO:000995210.015
response to mechanical stimulusGO:00096121340.015
response to molecule of bacterial originGO:00022371940.015
hormone transportGO:00099141210.015
cytosolic calcium ion homeostasisGO:00514801400.015
single organism carbohydrate metabolic processGO:00447231180.015
mapk cascadeGO:00001651400.015
calcium ion transportGO:00068161310.015
behaviorGO:00076102050.015
regulation of response to external stimulusGO:00321011060.015
negative regulation of rna metabolic processGO:00512531230.015
inorganic ion transmembrane transportGO:00986602290.015
response to radiationGO:00093141370.015
purine nucleotide catabolic processGO:00061951360.015
divalent inorganic cation transportGO:00725111340.015
regulation of anatomical structure sizeGO:00900661350.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
synaptic transmissionGO:00072682350.015
vesicle mediated transportGO:00161921810.015
gland developmentGO:00487321550.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
regulation of cell motilityGO:20001451310.015
nucleotide catabolic processGO:00091661390.015
purine nucleoside catabolic processGO:00061521240.014
response to campGO:0051591910.014
positive regulation of rna metabolic processGO:00512542030.014
cellular lipid metabolic processGO:00442552080.014
response to alkaloidGO:00432791320.014
hormone secretionGO:00468791150.014
positive regulation of signal transductionGO:00099671750.014
regulation of protein kinase activityGO:00458591050.014
monovalent inorganic cation transportGO:00156721720.014
nucleoside phosphate catabolic processGO:19012921400.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
circulatory system processGO:00030131830.014
positive regulation of cell motilityGO:2000147970.014
regulation of cellular catabolic processGO:00313291010.014
ribonucleoside catabolic processGO:00424541260.014
gastrulationGO:000736920.014
response to estradiolGO:00323551640.014
sexual reproductionGO:00199531480.014
cation transmembrane transportGO:00986552630.014
regulation of nucleotide metabolic processGO:00061401170.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
cellular protein localizationGO:00346131220.014
regulation of blood circulationGO:19035221100.014
response to ketoneGO:19016541820.014
salivary gland developmentGO:000743130.014
organophosphate catabolic processGO:00464341480.014
reproductive system developmentGO:00614581280.013
establishment of protein localizationGO:00451841410.013
regulation of catabolic processGO:00098941130.013
negative regulation of cell differentiationGO:0045596990.013
amide transportGO:00428861050.013
purine ribonucleoside catabolic processGO:00461301240.013
membrane organizationGO:0061024940.013
negative regulation of rna biosynthetic processGO:19026791180.013
negative regulation of innate immune responseGO:004582440.013
leukocyte cell cell adhesionGO:000715940.013
response to reactive oxygen speciesGO:00003021200.013
positive regulation of cellular component movementGO:00512721020.013
regulation of hormone secretionGO:00468831060.013
regulation of anatomical structure morphogenesisGO:00226031410.013
response to transition metal nanoparticleGO:19902671220.013
gliogenesisGO:0042063930.013
nucleoside catabolic processGO:00091641260.013
positive regulation of neuron differentiationGO:00456661260.013
peptidyl tyrosine phosphorylationGO:0018108720.013
anion transportGO:00068201780.013
cell morphogenesisGO:00009021420.013
neuron deathGO:00709971270.013
regulation of homeostatic processGO:00328441010.013
protein transportGO:00150311320.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
reactive nitrogen species metabolic processGO:200105710.013
response to lipopolysaccharideGO:00324961910.012
regulation of body fluid levelsGO:0050878900.012
response to hydrogen peroxideGO:0042542890.012
positive regulation of immune system processGO:0002684900.012
nucleoside triphosphate catabolic processGO:00091431230.012
neuron projection morphogenesisGO:00488121220.012
cellular macromolecule localizationGO:00707271220.012
growthGO:00400071650.012
reactive oxygen species biosynthetic processGO:190340980.012
endocytosisGO:0006897840.012
appendage morphogenesisGO:003510740.012
response to other organismGO:00517072200.012
negative regulation of catalytic activityGO:00430861030.012
negative regulation of transcription dna templatedGO:00458921160.012
positive regulation of cell projection organizationGO:00313461110.012
cytoplasmic transportGO:00164821150.012
axis specificationGO:000979840.012
multi multicellular organism processGO:00447061380.012
negative regulation of natural killer cell mediated immunityGO:000271640.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
dephosphorylationGO:0016311980.012
cell projection morphogenesisGO:00488581230.012
potassium ion transportGO:0006813970.012
taxisGO:0042330670.012
reactive oxygen species metabolic processGO:0072593370.012
ossificationGO:0001503700.012
organophosphate biosynthetic processGO:00904071430.012
regulation of cell cycleGO:0051726730.012
response to toxic substanceGO:00096361330.012
response to amino acidGO:0043200750.012
mesoderm developmentGO:000749820.012
cellular response to extracellular stimulusGO:0031668730.012
sequestering of calcium ionGO:005120880.012
developmental growthGO:00485891000.012
positive regulation of cell migrationGO:0030335960.012
muscle system processGO:00030121150.012
response to vitaminGO:00332731310.012
cellular response to cytokine stimulusGO:00713451270.012
regulation of neuron deathGO:19012141150.012
regulation of canonical wnt signaling pathwayGO:006082840.012
negative regulation of phosphorus metabolic processGO:0010563800.012
inorganic cation transmembrane transportGO:00986622020.012
chromosome segregationGO:000705920.011
peptidyl tyrosine modificationGO:0018212720.011
regulation of neuron projection developmentGO:00109751610.011
embryonic pattern specificationGO:000988010.011
sex differentiationGO:00075481130.011
glycosyl compound catabolic processGO:19016581260.011
positive regulation of nucleotide metabolic processGO:0045981910.011
limb morphogenesisGO:003510840.011
single organism organelle organizationGO:19025891800.011
positive regulation of mapk cascadeGO:0043410920.011
regulation of mapk cascadeGO:00434081160.011
cell growthGO:00160491040.011
lipid storageGO:001991510.011
carbohydrate metabolic processGO:00059751300.011
monocarboxylic acid metabolic processGO:00327871520.011
reproductive structure developmentGO:00486081280.011
epithelium developmentGO:0060429960.011
cell type specific apoptotic processGO:00972851340.011
negative regulation of cell cycle phase transitionGO:190198840.011
positive regulation of transferase activityGO:0051347810.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
axon developmentGO:0061564960.011
developmental process involved in reproductionGO:00030061590.011
cell part morphogenesisGO:00329901230.011
action potentialGO:0001508540.011
forebrain developmentGO:0030900980.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
negative regulation of signal transductionGO:0009968830.011
cellular response to alcoholGO:0097306870.011
response to tumor cellGO:000234740.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
female pregnancyGO:00075651220.011
organic anion transportGO:00157111320.011
cofactor metabolic processGO:0051186950.011
regulation of peptide hormone secretionGO:0090276800.011
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.011
positive regulation of neuron projection developmentGO:0010976990.011
transmission of nerve impulseGO:0019226420.011
maintenance of locationGO:0051235170.011
cellular response to insulin stimulusGO:0032869810.011
gonad developmentGO:00084061040.010
regulation of nucleoside metabolic processGO:0009118660.010
chemosensory behaviorGO:000763520.010
rho protein signal transductionGO:0007266110.010
regulation of peptide transportGO:0090087870.010
positive regulation of cellular catabolic processGO:0031331710.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
sequestering of metal ionGO:005123890.010
immune response to tumor cellGO:000241830.010
protein maturationGO:0051604680.010
hepaticobiliary system developmentGO:0061008900.010
protein homooligomerizationGO:0051260910.010
multicellular organismal signalingGO:0035637440.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
defense response to gram negative bacteriumGO:005082930.010
negative regulation of secretionGO:0051048820.010
single organism membrane organizationGO:0044802740.010
coenzyme metabolic processGO:0006732860.010
activation of cysteine type endopeptidase activityGO:009720240.010
actin filament based processGO:0030029860.010
cell cycleGO:00070491010.010
tube developmentGO:0035295890.010
cytokine biosynthetic processGO:004208930.010
gamete generationGO:00072761240.010
negative regulation of cell proliferationGO:00082851190.010
rhythmic processGO:00485111560.010
positive regulation of nucleoside metabolic processGO:0045979550.010

Prg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.035
central nervous system diseaseDOID:33100.016
disease of metabolismDOID:001466700.015
musculoskeletal system diseaseDOID:1700.014
sensory system diseaseDOID:005015500.014
inherited metabolic disorderDOID:65500.012
eye and adnexa diseaseDOID:149200.012
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011