Rattus norvegicus

0 known processes

Akt1s1

AKT1 substrate 1 (proline-rich)

(Aliases: PRAS40)

Akt1s1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161921810.281
gtp catabolic processGO:0006184710.189
positive regulation of nucleic acid templated transcriptionGO:19035081970.162
single organism intracellular transportGO:19025821660.155
regulation of signal transductionGO:00099663180.140
cellular macromolecule localizationGO:00707271220.127
regulation of nucleic acid templated transcriptionGO:19035063800.125
protein targetingGO:0006605610.119
cellular protein localizationGO:00346131220.119
cellular component assemblyGO:00226073600.117
positive regulation of macromolecule biosynthetic processGO:00105572470.115
intracellular protein transportGO:0006886790.108
regulation of proteasomal protein catabolic processGO:006113640.105
positive regulation of transcription factor import into nucleusGO:004299340.103
secretionGO:00469033070.102
regulation of cell proliferationGO:00421273590.102
nucleic acid templated transcriptionGO:00976593790.099
positive regulation of rna metabolic processGO:00512542030.098
carboxylic acid metabolic processGO:00197522890.098
establishment of protein localizationGO:00451841410.088
protein transportGO:00150311320.086
regulation of protein metabolic processGO:00512462890.082
positive regulation of nucleobase containing compound metabolic processGO:00459353190.082
lipid metabolic processGO:00066292830.082
carboxylic acid transportGO:00469421150.081
rna biosynthetic processGO:00327743800.080
ensheathment of neuronsGO:0007272400.079
positive regulation of signalingGO:00230562700.078
regulation of rna metabolic processGO:00512523910.075
cellular response to endogenous stimulusGO:00714953770.075
rna metabolic processGO:00160704060.075
programmed cell deathGO:00125013920.075
positive regulation of cellular biosynthetic processGO:00313282950.074
apoptotic processGO:00069153810.074
macromolecule localizationGO:00330362520.072
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.072
regulation of molecular functionGO:00650093980.071
intracellular transportGO:00469071850.069
positive regulation of transcription dna templatedGO:00458931970.067
positive regulation of nitrogen compound metabolic processGO:00511733340.067
neurological system processGO:00508772190.063
regulation of rna biosynthetic processGO:20011413810.062
positive regulation of gene expressionGO:00106282440.061
anion transportGO:00068201780.061
protein localizationGO:00081041910.059
aromatic compound catabolic processGO:00194391680.059
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.056
negative regulation of transcription dna templatedGO:00458921160.055
multi multicellular organism processGO:00447061380.054
regulation of transcription dna templatedGO:00063553740.054
single organism catabolic processGO:00447122830.053
positive regulation of phosphorus metabolic processGO:00105622620.053
positive regulation of rna biosynthetic processGO:19026801970.052
neuron deathGO:00709971270.051
positive regulation of cell communicationGO:00106472710.050
purine nucleoside triphosphate metabolic processGO:00091441410.050
purine containing compound catabolic processGO:00725231380.050
synaptic transmissionGO:00072682350.050
transcription dna templatedGO:00063513770.048
organophosphate catabolic processGO:00464341480.048
regulation of cellular catabolic processGO:00313291010.047
cellular response to starvationGO:0009267270.047
organelle organizationGO:00069962660.046
macromolecular complex assemblyGO:00650032730.046
single organism reproductive processGO:00447022970.046
positive regulation of transportGO:00510502450.046
rhythmic processGO:00485111560.046
anion transmembrane transportGO:0098656770.045
tissue developmentGO:00098882520.044
negative regulation of gene expressionGO:00106291990.044
cellular response to oxygen containing compoundGO:19017013860.044
regulation of synaptic transmissionGO:00508041410.043
single organism membrane organizationGO:0044802740.043
response to ethanolGO:00454711620.041
muscle cell proliferationGO:0033002840.041
cellular protein catabolic processGO:0044257190.041
regulation of phosphorus metabolic processGO:00511743490.040
regulation of cellular protein metabolic processGO:00322682670.040
negative regulation of rna metabolic processGO:00512531230.040
regulation of cellular localizationGO:00603412630.040
protein oligomerizationGO:00512591910.039
amino acid transportGO:0006865700.039
cellular component biogenesisGO:00440853680.038
regulation of apoptotic processGO:00429813350.038
protein complex assemblyGO:00064612630.037
membrane organizationGO:0061024940.037
positive regulation of cellular protein metabolic processGO:00322701670.037
cytoplasmic transportGO:00164821150.036
positive regulation of cell proliferationGO:00082842490.036
positive regulation of apoptotic processGO:00430651540.036
regulation of programmed cell deathGO:00430673410.036
regulation of transcription from rna polymerase ii promoterGO:00063572340.036
circadian rhythmGO:0007623880.035
proteolysisGO:00065081750.035
negative regulation of transportGO:00510511360.035
signal transduction by phosphorylationGO:00230141440.035
anatomical structure morphogenesisGO:00096532980.035
negative regulation of biosynthetic processGO:00098901680.035
regulation of protein import into nucleusGO:0042306240.035
purine nucleotide catabolic processGO:00061951360.035
response to growth factorGO:00708481890.034
cell type specific apoptotic processGO:00972851340.034
positive regulation of programmed cell deathGO:00430681570.034
oxoacid metabolic processGO:00434362900.034
positive regulation of response to stimulusGO:00485842850.033
positive regulation of cell deathGO:00109421840.033
organophosphate metabolic processGO:00196373700.033
positive regulation of molecular functionGO:00440932300.032
gtp metabolic processGO:0046039720.032
protein complex biogenesisGO:00702712630.032
nucleotide catabolic processGO:00091661390.032
cellular response to organonitrogen compoundGO:00714171970.031
cellular response to hormone stimulusGO:00328702470.031
nucleobase containing compound catabolic processGO:00346551520.031
positive regulation of protein metabolic processGO:00512471780.031
endocytosisGO:0006897840.031
locomotionGO:00400112370.031
cellular macromolecule catabolic processGO:0044265290.031
regulation of neuronal synaptic plasticityGO:0048168310.031
negative regulation of programmed cell deathGO:00430691830.030
positive regulation of secretionGO:00510471400.030
regulation of cell differentiationGO:00455953200.030
cellular response to extracellular stimulusGO:0031668730.029
protein localization to organelleGO:0033365570.029
response to inorganic substanceGO:00100353770.029
behaviorGO:00076102050.029
regulation of gtpase activityGO:0043087570.028
regulation of lipid metabolic processGO:0019216680.028
cellular catabolic processGO:00442482950.028
positive regulation of cellular component movementGO:00512721020.028
proteolysis involved in cellular protein catabolic processGO:0051603190.028
organic substance catabolic processGO:19015753160.028
glycosyl compound catabolic processGO:19016581260.028
cellular response to growth factor stimulusGO:00713631620.028
neuronal action potentialGO:0019228350.028
response to extracellular stimulusGO:00099913800.027
reproductionGO:00000032450.027
cell cell signalingGO:00072673350.027
guanosine containing compound catabolic processGO:1901069710.027
wound healingGO:00420601220.027
regulation of neuron deathGO:19012141150.027
chemical homeostasisGO:00488782920.027
regulation of secretionGO:00510462240.027
protein catabolic processGO:0030163300.026
heterocycle catabolic processGO:00467001670.026
myelinationGO:0042552390.026
negative regulation of nucleic acid templated transcriptionGO:19035071170.026
lipid storageGO:001991510.026
purine ribonucleoside triphosphate catabolic processGO:00092071220.026
transmission of nerve impulseGO:0019226420.026
cellular response to organic cyclic compoundGO:00714072020.026
transcription from rna polymerase ii promoterGO:00063662520.026
localization of cellGO:00516742020.026
cell motilityGO:00488702020.025
enzyme linked receptor protein signaling pathwayGO:00071671160.025
purine nucleoside catabolic processGO:00061521240.025
purine ribonucleoside metabolic processGO:00461281680.025
immune system processGO:00023762040.025
regulation of protein modification processGO:00313991940.025
nucleoside triphosphate catabolic processGO:00091431230.024
regulation of establishment of protein localizationGO:0070201690.024
regulation of protein targetingGO:1903533280.024
signal releaseGO:00230611450.024
regulation of catabolic processGO:00098941130.024
positive regulation of nf kappab import into nucleusGO:004234620.024
cellular chemical homeostasisGO:00550822470.024
regulation of neurogenesisGO:00507672470.024
catabolic processGO:00090563510.023
reactive oxygen species metabolic processGO:0072593370.023
regulation of synaptic plasticityGO:0048167700.023
central nervous system neuron axonogenesisGO:002195510.023
multicellular organism reproductionGO:00325042330.023
organic cyclic compound catabolic processGO:19013611750.023
response to nutrient levelsGO:00316673700.023
cellular response to nutrient levelsGO:0031669600.023
multi organism reproductive processGO:00447032620.023
regulation of reactive oxygen species metabolic processGO:2000377260.023
response to peptideGO:19016522920.023
negative regulation of signalingGO:00230571570.022
organonitrogen compound catabolic processGO:19015651790.022
glycosyl compound metabolic processGO:19016571820.022
negative regulation of rna biosynthetic processGO:19026791180.022
positive regulation of catalytic activityGO:00430851840.022
negative regulation of macromolecule metabolic processGO:00106052600.022
sexual reproductionGO:00199531480.022
negative regulation of cellular protein metabolic processGO:00322691060.022
purine ribonucleotide catabolic processGO:00091541360.022
epithelium developmentGO:0060429960.022
purine ribonucleoside triphosphate metabolic processGO:00092051400.021
vesicle fusionGO:0006906140.021
reproductive processGO:00224143720.021
cellular response to peptideGO:19016531330.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.021
multicellular organismal signalingGO:0035637440.021
regulation of intracellular protein transportGO:0033157340.021
ribonucleoside metabolic processGO:00091191740.021
organic acid metabolic processGO:00060822920.020
regulation of multicellular organismal developmentGO:20000263760.020
regulation of nucleotide catabolic processGO:0030811650.020
secretion by cellGO:00329402480.020
ribonucleoside triphosphate metabolic processGO:00091991410.020
regulation of peptide transportGO:0090087870.020
cellular response to external stimulusGO:00714961180.020
regulation of phosphate metabolic processGO:00192203490.020
axon ensheathmentGO:0008366400.020
protein importGO:0017038370.020
positive regulation of multicellular organismal processGO:00512403870.019
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
negative regulation of protein metabolic processGO:00512481140.019
cellular response to cytokine stimulusGO:00713451270.019
regulation of cell cycle g2 m phase transitionGO:190274940.019
negative regulation of cell developmentGO:0010721820.018
female pregnancyGO:00075651220.018
multicellular organism growthGO:003526410.018
single organism cellular localizationGO:19025801020.018
regulation of nucleocytoplasmic transportGO:0046822280.018
nucleoside metabolic processGO:00091161790.018
positive regulation of cell developmentGO:00107201760.018
cellular response to peptide hormone stimulusGO:00713751200.018
negative regulation of metabolic processGO:00098923310.018
glycerolipid metabolic processGO:0046486670.018
learning or memoryGO:0007611900.018
positive regulation of biosynthetic processGO:00098913190.018
developmental process involved in reproductionGO:00030061590.018
response to starvationGO:0042594590.018
positive regulation of phosphorylationGO:00423271770.018
protein complex subunit organizationGO:00718223020.018
purine ribonucleotide metabolic processGO:00091502270.018
jnk cascadeGO:0007254280.018
protein heterooligomerizationGO:0051291890.018
cellular nitrogen compound catabolic processGO:00442701630.018
antigen processing and presentationGO:001988220.018
peptide transportGO:0015833970.018
nucleoside phosphate catabolic processGO:19012921400.017
action potentialGO:0001508540.017
single organism organelle organizationGO:19025891800.017
response to heatGO:0009408600.017
hormone transportGO:00099141210.017
regulation of nervous system developmentGO:00519602640.017
regulation of cellular component biogenesisGO:0044087860.017
response to glucoseGO:00097491360.017
positive regulation of cell differentiationGO:00455972170.017
nuclear transportGO:0051169490.017
negative regulation of nervous system developmentGO:0051961790.017
regulation of protein kinase activityGO:00458591050.016
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.016
smooth muscle cell proliferationGO:0048659770.016
negative regulation of cellular metabolic processGO:00313242810.016
regulation of phosphorylationGO:00423252480.016
cellular amine metabolic processGO:0044106380.016
response to glucocorticoidGO:00513842230.016
protein import into nucleusGO:0006606350.016
positive regulation of odontogenesis of dentin containing toothGO:004248810.016
maintenance of locationGO:0051235170.016
regulation of protein transportGO:0051223680.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
macromolecule catabolic processGO:0009057580.016
central nervous system developmentGO:00074173110.016
establishment of protein localization to organelleGO:0072594440.016
positive regulation of protein modification processGO:00314011420.016
positive regulation of transferase activityGO:0051347810.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.016
response to corticosteroidGO:00319602350.016
regulation of arp2 3 complex mediated actin nucleationGO:003431520.016
macroautophagyGO:001623640.015
modification dependent macromolecule catabolic processGO:0043632140.015
anterior posterior pattern specificationGO:000995210.015
organic acid catabolic processGO:0016054490.015
activation of phospholipase d activityGO:003158420.015
carbohydrate derivative metabolic processGO:19011353460.015
positive regulation of developmental processGO:00510942830.015
response to nutrientGO:00075842480.015
hexose metabolic processGO:0019318580.015
cellular lipid metabolic processGO:00442552080.015
response to woundingGO:00096112540.015
positive regulation of signal transductionGO:00099671750.015
regulation of intracellular signal transductionGO:19025312180.015
regulation of smooth muscle cell proliferationGO:0048660750.015
transforming growth factor beta receptor signaling pathwayGO:0007179180.015
chemosensory behaviorGO:000763520.015
positive regulation of phosphate metabolic processGO:00459372620.015
cell cycleGO:00070491010.015
regulation of jnk cascadeGO:0046328190.015
regulation of catalytic activityGO:00507903040.015
homeostatic processGO:00425923310.015
regulation of intracellular transportGO:0032386650.014
intracellular signal transductionGO:00355563140.014
cellular homeostasisGO:00197252520.014
positive regulation of secretion by cellGO:19035321280.014
nucleocytoplasmic transportGO:0006913480.014
positive regulation of cellular catabolic processGO:0031331710.014
agingGO:00075682410.014
organelle localizationGO:0051640550.014
positive regulation of nervous system developmentGO:00519621780.014
amide transportGO:00428861050.014
head developmentGO:00603222470.014
positive regulation of catabolic processGO:0009896780.014
nuclear importGO:0051170350.014
regulation of fat cell differentiationGO:004559830.014
regulation of nf kappab import into nucleusGO:004234550.013
response to hypoxiaGO:00016662310.013
lipid biosynthetic processGO:00086101280.013
reactive nitrogen species metabolic processGO:200105710.013
regulation of cell cycleGO:0051726730.013
ras protein signal transductionGO:0007265290.013
regulation of protein maturationGO:1903317500.013
defense responseGO:00069521940.013
positive regulation of neurogenesisGO:00507691650.013
negative regulation of cellular component organizationGO:0051129830.013
positive regulation of cellular amine metabolic processGO:003324030.013
dephosphorylationGO:0016311980.013
response to hexoseGO:00097461440.013
positive regulation of locomotionGO:00400171020.013
olfactory behaviorGO:004204820.013
neuromuscular synaptic transmissionGO:000727420.013
monocarboxylic acid transportGO:0015718520.013
positive regulation of neuron deathGO:1901216430.013
single organism nuclear importGO:1902593350.012
single organism behaviorGO:00447081300.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
energy derivation by oxidation of organic compoundsGO:0015980460.012
regulation of hydrolase activityGO:00513361430.012
nucleotide metabolic processGO:00091172790.012
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.012
small gtpase mediated signal transductionGO:0007264360.012
neuron apoptotic processGO:0051402880.012
protein targeting to nucleusGO:0044744350.012
negative regulation of apoptotic processGO:00430661810.012
organic acid transportGO:00158491160.012
salivary gland morphogenesisGO:000743510.012
response to carbohydrateGO:00097431830.012
nucleobase containing small molecule metabolic processGO:00550863160.012
regulation of cell developmentGO:00602842630.012
positive regulation of intracellular signal transductionGO:19025331380.012
endosomal transportGO:0016197140.012
response to monosaccharideGO:00342841590.012
positive regulation of cellular component organizationGO:00511302000.012
memoryGO:0007613540.012
nucleoside catabolic processGO:00091641260.012
regulation of purine nucleotide catabolic processGO:0033121650.012
response to transforming growth factor betaGO:0071559460.012
synaptic growth at neuromuscular junctionGO:005112410.012
regulation of transforming growth factor beta receptor signaling pathwayGO:001701550.012
response to cytokineGO:00340972150.012
cellular macromolecular complex assemblyGO:0034622580.012
cellular response to stressGO:00335542690.012
regulation of cellular ketone metabolic processGO:0010565270.012
cell projection organizationGO:00300303020.011
axonogenesisGO:0007409710.011
negative regulation of response to stimulusGO:00485851550.011
cell cycle g1 s phase transitionGO:0044843130.011
sulfur compound metabolic processGO:0006790700.011
regulation of body fluid levelsGO:0050878900.011
regulation of proteolysisGO:0030162660.011
ribonucleotide metabolic processGO:00092592310.011
positive regulation of smooth muscle cell proliferationGO:0048661510.011
cation transportGO:00068123820.011
cation homeostasisGO:00550801950.011
protein localization to nucleusGO:0034504390.011
multicellular organismal reproductive processGO:00486092330.011
organic anion transportGO:00157111320.011
positive regulation of hydrolase activityGO:0051345860.011
gamete generationGO:00072761240.011
membrane fusionGO:0061025260.011
ribose phosphate metabolic processGO:00196932350.011
behavioral response to ethanolGO:004814910.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
cellular ketone metabolic processGO:0042180510.011
cellular protein complex assemblyGO:0043623440.011
vesicle organizationGO:0016050290.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
response to antibioticGO:0046677390.011
amine metabolic processGO:0009308380.011
cellular response to biotic stimulusGO:0071216590.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
reproductive structure developmentGO:00486081280.011
reproductive system developmentGO:00614581280.011
sensory organ developmentGO:0007423740.011
phospholipid biosynthetic processGO:0008654290.011
macromolecular complex subunit organizationGO:00439333390.011
response to peptide hormoneGO:00434342780.011
positive regulation of hormone secretionGO:0046887650.011
regulation of odontogenesis of dentin containing toothGO:004248720.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243630.010
regulation of neuron projection developmentGO:00109751610.010
motor neuron axon guidanceGO:000804510.010
glial cell differentiationGO:0010001650.010
regulation of epithelial cell proliferationGO:0050678490.010
proteasomal protein catabolic processGO:001049880.010
biological adhesionGO:00226101100.010
negative regulation of molecular functionGO:00440921330.010
glucose metabolic processGO:0006006520.010
guanosine containing compound metabolic processGO:1901068740.010
negative regulation of jnk cascadeGO:004632940.010
carbohydrate derivative catabolic processGO:19011361470.010
negative regulation of cell communicationGO:00106481580.010
regulation of notch signaling pathwayGO:000859330.010
gliogenesisGO:0042063930.010
tube developmentGO:0035295890.010
ubiquitin dependent protein catabolic processGO:0006511140.010

Akt1s1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
nervous system diseaseDOID:86300.032
organ system cancerDOID:005068600.026
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.026
gastrointestinal system cancerDOID:311900.026
disease of metabolismDOID:001466700.014
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
intestinal cancerDOID:1015500.012