Rattus norvegicus

235 known processes

Kdr

kinase insert domain receptor

(Aliases: Vegfr-2,MGC93590)

Kdr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular component movementGO:00512721020.292
cell motilityGO:00488702020.224
cellular component movementGO:00069282480.217
positive regulation of cell motilityGO:2000147970.209
regenerationGO:00310991630.204
circulatory system developmentGO:00723591340.203
positive regulation of transcription dna templatedGO:00458931970.196
organ regenerationGO:00311001010.190
response to peptideGO:19016522920.187
regulation of phosphate metabolic processGO:00192203490.185
localization of cellGO:00516742020.178
regulation of stem cell differentiationGO:200073620.167
angiogenesisGO:0001525530.165
regulation of multicellular organismal developmentGO:20000263760.164
blood vessel developmentGO:0001568690.163
cardiovascular system developmentGO:00723581340.160
regulation of locomotionGO:00400121480.154
regulation of anatomical structure morphogenesisGO:00226031410.151
blood vessel morphogenesisGO:0048514580.151
positive regulation of signalingGO:00230562700.149
protein phosphorylationGO:00064683450.144
cellular response to endogenous stimulusGO:00714953770.138
response to estrogenGO:00436272320.138
positive regulation of nucleobase containing compound metabolic processGO:00459353190.132
gland developmentGO:00487321550.131
regulation of transcription dna templatedGO:00063553740.130
rna metabolic processGO:00160704060.130
regulation of nucleic acid templated transcriptionGO:19035063800.128
vasculogenesisGO:000157030.128
cellular component biogenesisGO:00440853680.125
response to oxygen levelsGO:00704822650.123
response to growth factorGO:00708481890.123
protein autophosphorylationGO:0046777660.119
oxoacid metabolic processGO:00434362900.118
response to decreased oxygen levelsGO:00362932370.116
apoptotic processGO:00069153810.114
positive regulation of phosphorus metabolic processGO:00105622620.111
cellular response to hormone stimulusGO:00328702470.109
regulation of cell motilityGO:20001451310.109
response to insulinGO:00328681330.107
enzyme linked receptor protein signaling pathwayGO:00071671160.107
positive regulation of macromolecule biosynthetic processGO:00105572470.107
negative regulation of multicellular organismal processGO:00512412030.101
response to estradiolGO:00323551640.100
regulation of transcription from rna polymerase ii promoterGO:00063572340.100
positive regulation of cell migrationGO:0030335960.099
transcription from rna polymerase ii promoterGO:00063662520.099
carboxylic acid metabolic processGO:00197522890.098
positive regulation of phosphate metabolic processGO:00459372620.097
positive regulation of biosynthetic processGO:00098913190.097
response to peptide hormoneGO:00434342780.097
regulation of signal transductionGO:00099663180.096
neuron differentiationGO:00301823680.094
response to carbohydrateGO:00097431830.092
anatomical structure morphogenesisGO:00096532980.090
regulation of apoptotic processGO:00429813350.089
regulation of rna metabolic processGO:00512523910.088
regulation of cell migrationGO:00303341280.085
cellular response to oxygen containing compoundGO:19017013860.084
intracellular signal transductionGO:00355563140.082
regulation of molecular functionGO:00650093980.081
positive regulation of nitrogen compound metabolic processGO:00511733340.081
regulation of phosphorus metabolic processGO:00511743490.080
regulation of cell proliferationGO:00421273590.075
transcription dna templatedGO:00063513770.075
positive regulation of cell communicationGO:00106472710.074
programmed cell deathGO:00125013920.074
regulation of phosphorylationGO:00423252480.074
urogenital system developmentGO:0001655780.073
anterior posterior pattern specificationGO:000995210.072
cellular amino acid metabolic processGO:00065201070.072
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.072
regulation of programmed cell deathGO:00430673410.071
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.071
response to toxic substanceGO:00096361330.070
negative regulation of response to stimulusGO:00485851550.068
regulation of neuron differentiationGO:00456642080.068
nucleic acid templated transcriptionGO:00976593790.068
chemical homeostasisGO:00488782920.067
cell migrationGO:00164771970.066
negative regulation of developmental processGO:00510931250.062
rna biosynthetic processGO:00327743800.062
cellular catabolic processGO:00442482950.061
regulation of cellular component organizationGO:00511283680.061
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.060
regulation of neurogenesisGO:00507672470.060
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.060
reproductive processGO:00224143720.059
single organism reproductive processGO:00447022970.058
regulation of cellular protein metabolic processGO:00322682670.058
regulation of protein modification processGO:00313991940.058
negative regulation of biosynthetic processGO:00098901680.058
negative regulation of nitrogen compound metabolic processGO:00511721610.057
regulation of nervous system developmentGO:00519602640.057
nuclear body organizationGO:003057510.057
aromatic compound catabolic processGO:00194391680.056
negative regulation of cell proliferationGO:00082851190.056
positive regulation of endothelial cell migrationGO:001059540.056
cellular component assemblyGO:00226073600.056
positive regulation of cell differentiationGO:00455972170.055
negative regulation of macromolecule biosynthetic processGO:00105581480.055
negative regulation of cell deathGO:00605482290.054
positive regulation of locomotionGO:00400171020.054
response to oxidative stressGO:00069791860.054
organ morphogenesisGO:0009887750.054
negative regulation of macromolecule metabolic processGO:00106052600.053
response to radiationGO:00093141370.053
negative regulation of nucleobase containing compound metabolic processGO:00459341530.053
positive regulation of nervous system developmentGO:00519621780.053
regulation of cellular component movementGO:00512701500.051
negative regulation of rna metabolic processGO:00512531230.050
locomotionGO:00400112370.050
homeostatic processGO:00425923310.050
cell projection organizationGO:00300303020.050
neuron projection developmentGO:00311752730.050
response to corticosteroidGO:00319602350.049
positive regulation of cellular protein metabolic processGO:00322701670.049
peptidyl amino acid modificationGO:00181931260.049
negative regulation of cellular metabolic processGO:00313242810.049
ameboidal type cell migrationGO:0001667260.048
reproductionGO:00000032450.048
positive regulation of developmental processGO:00510942830.048
peptidyl tyrosine modificationGO:0018212720.048
cellular response to growth factor stimulusGO:00713631620.048
vasculature developmentGO:0001944700.048
positive regulation of rna metabolic processGO:00512542030.047
positive regulation of cell proliferationGO:00082842490.047
positive regulation of immune system processGO:0002684900.047
regulation of cellular localizationGO:00603412630.047
nucleobase containing small molecule metabolic processGO:00550863160.047
motor neuron axon guidanceGO:000804510.047
ribonucleotide metabolic processGO:00092592310.046
response to inorganic substanceGO:00100353770.046
multicellular organismal reproductive processGO:00486092330.045
regulation of catalytic activityGO:00507903040.045
regulation of system processGO:00440572080.045
cellular ketone metabolic processGO:0042180510.045
catabolic processGO:00090563510.045
regulation of cellular ketone metabolic processGO:0010565270.045
response to ketoneGO:19016541820.044
cell chemotaxisGO:0060326310.044
developmental process involved in reproductionGO:00030061590.044
regulation of ion transportGO:00432692450.043
cellular response to organic cyclic compoundGO:00714072020.043
neurological system processGO:00508772190.043
leukocyte activationGO:0045321760.042
response to glucocorticoidGO:00513842230.042
kidney developmentGO:0001822670.041
positive regulation of multicellular organismal processGO:00512403870.041
response to hypoxiaGO:00016662310.041
small gtpase mediated signal transductionGO:0007264360.041
organic acid metabolic processGO:00060822920.041
embryonic axis specificationGO:000057810.041
regulation of epithelial cell migrationGO:0010632170.041
positive regulation of phosphorylationGO:00423271770.041
regulation of homeostatic processGO:00328441010.040
lipid metabolic processGO:00066292830.040
regulation of cell differentiationGO:00455953200.040
multi organism reproductive processGO:00447032620.040
cell morphogenesisGO:00009021420.040
negative regulation of programmed cell deathGO:00430691830.040
endochondral ossificationGO:000195820.039
renal system developmentGO:0072001670.039
response to monosaccharideGO:00342841590.039
negative regulation of neuron differentiationGO:0045665620.039
multicellular organism reproductionGO:00325042330.039
negative regulation of cellular biosynthetic processGO:00313271610.038
response to nutrientGO:00075842480.038
positive regulation of gene expressionGO:00106282440.038
wound healingGO:00420601220.038
negative regulation of cell differentiationGO:0045596990.038
regulation of neuron projection developmentGO:00109751610.038
glomerulus developmentGO:0032835100.038
positive regulation of molecular functionGO:00440932300.037
secretionGO:00469033070.037
regulation of immune system processGO:00026821230.037
positive regulation of cellular biosynthetic processGO:00313282950.037
cell morphogenesis involved in differentiationGO:00009041190.037
embryonic pattern specificationGO:000988010.037
negative regulation of transcription dna templatedGO:00458921160.036
negative regulation of apoptotic processGO:00430661810.036
positive regulation of signal transductionGO:00099671750.036
regulation of cellular amine metabolic processGO:003323880.036
cellular amine metabolic processGO:0044106380.036
positive regulation of response to stimulusGO:00485842850.036
regulation of response to external stimulusGO:00321011060.036
cellular response to nitrogen compoundGO:19016992100.035
pro t cell differentiationGO:000257210.035
regulation of protein phosphorylationGO:00019321830.035
positive regulation of catalytic activityGO:00430851840.035
response to reactive oxygen speciesGO:00003021200.035
blood circulationGO:00080151830.035
regulation of rna biosynthetic processGO:20011413810.035
central nervous system developmentGO:00074173110.035
regulation of ossificationGO:0030278320.034
cell projection morphogenesisGO:00488581230.034
cellular response to steroid hormone stimulusGO:0071383930.034
regulation of response to stressGO:00801341260.034
ras protein signal transductionGO:0007265290.033
positive regulation of neurogenesisGO:00507691650.033
neuron developmentGO:00486662860.033
regulation of hormone levelsGO:00108171870.033
positive regulation of protein phosphorylationGO:00019341350.033
axis specificationGO:000979840.033
cellular response to alcoholGO:0097306870.033
epithelial cell migrationGO:0010631190.033
regulation of cellular amino acid metabolic processGO:000652120.033
negative regulation of neurogenesisGO:0050768780.033
peptidyl tyrosine phosphorylationGO:0018108720.032
transmembrane transportGO:00550854120.032
cell morphogenesis involved in neuron differentiationGO:00486671060.031
amine metabolic processGO:0009308380.031
regulation of canonical wnt signaling pathwayGO:006082840.031
negative regulation of cell communicationGO:00106481580.031
organic substance catabolic processGO:19015753160.031
bone developmentGO:0060348250.031
organelle organizationGO:00069962660.031
cellular response to stressGO:00335542690.031
bmp signaling pathwayGO:003050940.031
taxisGO:0042330670.030
ossificationGO:0001503700.030
nucleotide metabolic processGO:00091172790.030
sexual reproductionGO:00199531480.030
cellular response to reactive oxygen speciesGO:0034614550.030
regulation of chemotaxisGO:0050920290.030
positive regulation of rna biosynthetic processGO:19026801970.030
divalent inorganic cation homeostasisGO:00725071650.029
neuron apoptotic processGO:0051402880.029
molting cycle processGO:002240420.029
positive regulation of transportGO:00510502450.029
tissue developmentGO:00098882520.028
anion transportGO:00068201780.028
cell cycleGO:00070491010.028
calcium ion homeostasisGO:00550741620.028
female pregnancyGO:00075651220.028
cell cell junction organizationGO:0045216200.028
positive regulation of apoptotic processGO:00430651540.028
negative regulation of nervous system developmentGO:0051961790.028
regulation of protein metabolic processGO:00512462890.028
response to external biotic stimulusGO:00432072210.028
carbohydrate derivative metabolic processGO:19011353460.028
positive regulation of cellular amine metabolic processGO:003324030.027
b cell differentiationGO:003018320.027
positive regulation of protein metabolic processGO:00512471780.027
cellular response to peptideGO:19016531330.027
cytosolic calcium ion homeostasisGO:00514801400.027
cation transportGO:00068123820.026
cellular lipid metabolic processGO:00442552080.026
negative regulation of gene expressionGO:00106291990.026
negative regulation of cellular component organizationGO:0051129830.026
coronary vasculature morphogenesisGO:006097730.026
nucleoside phosphate metabolic processGO:00067532830.026
regulation of cell morphogenesisGO:0022604770.026
regulation of kinase activityGO:00435491170.026
anatomical structure formation involved in morphogenesisGO:0048646830.025
gliogenesisGO:0042063930.025
response to ethanolGO:00454711620.025
secretion by cellGO:00329402480.025
hair cycle processGO:002240520.025
cardiac ventricle developmentGO:000323110.025
response to biotic stimulusGO:00096072260.025
regulation of intracellular signal transductionGO:19025312180.025
neuron deathGO:00709971270.025
head developmentGO:00603222470.025
protein complex assemblyGO:00064612630.024
mesoderm developmentGO:000749820.024
regulation of membrane potentialGO:00423911100.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
cellular response to lipidGO:00713962010.024
innate immune responseGO:0045087350.024
skeletal system developmentGO:0001501410.024
single organism catabolic processGO:00447122830.024
positive regulation of cellular component organizationGO:00511302000.024
macromolecular complex subunit organizationGO:00439333390.024
protein complex subunit organizationGO:00718223020.023
regulation of nucleotide metabolic processGO:00061401170.023
multi multicellular organism processGO:00447061380.023
response to lipopolysaccharideGO:00324961910.023
cellular response to glucocorticoid stimulusGO:0071385680.023
heart morphogenesisGO:000300730.023
regulation of cell growthGO:0001558850.023
regulation of cell projection organizationGO:00313441750.023
vesicle mediated transportGO:00161921810.023
heart valve morphogenesisGO:000317910.023
cellular response to corticosteroid stimulusGO:0071384690.022
purine nucleoside triphosphate catabolic processGO:00091461220.022
camera type eye developmentGO:0043010480.022
positive regulation of transferase activityGO:0051347810.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
positive regulation of neuron differentiationGO:00456661260.022
circulatory system processGO:00030131830.022
neuronal action potentialGO:0019228350.022
jak stat cascadeGO:0007259260.022
regulation of myeloid cell differentiationGO:0045637120.022
response to light stimulusGO:0009416520.021
liver developmentGO:0001889900.021
stem cell divisionGO:001714540.021
positive regulation of protein modification processGO:00314011420.021
salivary gland developmentGO:000743130.021
brain developmentGO:00074202470.021
positive regulation of lipid kinase activityGO:009021820.021
cell part morphogenesisGO:00329901230.021
sex differentiationGO:00075481130.021
cellular response to organonitrogen compoundGO:00714171970.021
salivary gland morphogenesisGO:000743510.021
nucleotide catabolic processGO:00091661390.021
mechanoreceptor differentiationGO:004249020.021
organic anion transportGO:00157111320.021
cellular response to insulin stimulusGO:0032869810.021
action potentialGO:0001508540.021
macromolecular complex assemblyGO:00650032730.021
agingGO:00075682410.021
regulation of secretion by cellGO:19035302080.020
positive regulation of cell developmentGO:00107201760.020
purine containing compound metabolic processGO:00725212530.020
epithelium migrationGO:0090132190.020
negative regulation of rna biosynthetic processGO:19026791180.020
protein complex biogenesisGO:00702712630.020
regulation of lymphocyte migrationGO:200040110.020
positive regulation of kinase activityGO:0033674770.020
ion transmembrane transportGO:00342203650.020
response to nutrient levelsGO:00316673700.020
epiboly involved in wound healingGO:009050520.020
regulation of cell morphogenesis involved in differentiationGO:0010769720.020
negative regulation of protein import into nucleus translocationGO:003315910.020
growthGO:00400071650.020
neuron projection morphogenesisGO:00488121220.019
gamete generationGO:00072761240.019
purine containing compound catabolic processGO:00725231380.019
artery developmentGO:006084030.019
ribonucleoside catabolic processGO:00424541260.019
positive regulation of erk1 and erk2 cascadeGO:0070374290.019
cell differentiation involved in kidney developmentGO:006100540.019
ribose phosphate metabolic processGO:00196932350.019
metanephric comma shaped body morphogenesisGO:007227820.019
nucleoside metabolic processGO:00091161790.019
actin cytoskeleton organizationGO:0030036730.019
cell fate determinationGO:000170920.019
sensory perceptionGO:00076001010.019
regulation of anatomical structure sizeGO:00900661350.019
response to organophosphorusGO:00466831020.019
positive regulation of myeloid leukocyte differentiationGO:000276370.019
diencephalon developmentGO:0021536210.019
organic cyclic compound catabolic processGO:19013611750.019
metanephric s shaped body morphogenesisGO:007228420.019
response to ionizing radiationGO:0010212590.019
oligopeptide transportGO:000685740.018
cardiac chamber developmentGO:000320510.018
respiratory system developmentGO:0060541450.018
regulation of protein kinase activityGO:00458591050.018
cytoskeleton organizationGO:00070101110.018
cellular response to peptide hormone stimulusGO:00713751200.018
developmental growthGO:00485891000.018
steroid metabolic processGO:0008202730.018
organonitrogen compound biosynthetic processGO:19015661670.018
g protein coupled receptor signaling pathwayGO:00071862420.018
response to extracellular stimulusGO:00099913800.018
cell growthGO:00160491040.018
response to acid chemicalGO:00011012220.018
behaviorGO:00076102050.018
negative regulation of neuron projection developmentGO:0010977460.018
single organism biosynthetic processGO:00447113420.018
actin filament based processGO:0030029860.018
regulation of organ formationGO:000315620.018
negative regulation of metabolic processGO:00098923310.018
regulation of bmp signaling pathwayGO:003051020.018
cellular homeostasisGO:00197252520.018
response to hexoseGO:00097461440.018
regulation of cell developmentGO:00602842630.018
myeloid progenitor cell differentiationGO:000231810.018
metanephric mesenchymal cell migrationGO:003578920.017
epithelial cell proliferationGO:0050673540.017
developmental growth involved in morphogenesisGO:0060560330.017
regulation of transferase activityGO:00513381230.017
heterocycle catabolic processGO:00467001670.017
female sex differentiationGO:0046660590.017
response to mechanical stimulusGO:00096121340.017
leukocyte differentiationGO:0002521300.017
response to purine containing compoundGO:00140741260.017
immune system processGO:00023762040.017
organophosphate biosynthetic processGO:00904071430.017
ribonucleoside metabolic processGO:00091191740.017
reproductive structure developmentGO:00486081280.016
positive regulation of rap gtpase activityGO:003285440.016
regulation of growthGO:00400081050.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
regulation of leukocyte differentiationGO:1902105200.016
organic acid transportGO:00158491160.016
negative regulation of signalingGO:00230571570.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.016
digestive tract developmentGO:0048565390.016
negative regulation of response to external stimulusGO:0032102370.016
chromosome segregationGO:000705920.016
positive regulation of chemotaxisGO:0050921230.016
positive regulation of homeostatic processGO:0032846490.016
tube developmentGO:0035295890.016
rhythmic processGO:00485111560.016
regulation of mapk cascadeGO:00434081160.016
cellular response to cytokine stimulusGO:00713451270.016
germline stem cell asymmetric divisionGO:009872810.016
response to glucoseGO:00097491360.016
cellular response to oxidative stressGO:0034599760.016
hair cycleGO:004263330.016
response to high density lipoprotein particleGO:005509920.015
nitrogen compound transportGO:00717052290.015
reproductive system developmentGO:00614581280.015
negative regulation of phosphate metabolic processGO:0045936800.015
negative regulation of transportGO:00510511360.015
endochondral bone morphogenesisGO:006035070.015
axon developmentGO:0061564960.015
cellular nitrogen compound catabolic processGO:00442701630.015
positive regulation of intracellular signal transductionGO:19025331380.015
single organism intracellular transportGO:19025821660.015
hypothalamus developmentGO:0021854110.015
multicellular organismal signalingGO:0035637440.015
purine nucleotide metabolic processGO:00061632290.015
glial cell differentiationGO:0010001650.015
regulation of catabolic processGO:00098941130.015
nucleobase containing compound catabolic processGO:00346551520.015
extracellular matrix organizationGO:0030198130.015
negative regulation of cell developmentGO:0010721820.015
hair follicle developmentGO:000194220.015
cellular response to vascular endothelial growth factor stimulusGO:003592460.015
muscle structure developmentGO:0061061870.015
response to fluid shear stressGO:0034405160.015
cellular ion homeostasisGO:00068731840.015
muscle cell proliferationGO:0033002840.014
cytoplasmic transportGO:00164821150.014
spermatogenesisGO:0007283990.014
amide transportGO:00428861050.014
regulation of cell cycleGO:0051726730.014
lymphoid progenitor cell differentiationGO:000232020.014
synaptic transmissionGO:00072682350.014
neural crest cell developmentGO:001403220.014
organonitrogen compound catabolic processGO:19015651790.014
establishment of tissue polarityGO:000716420.014
positive regulation of secretion by cellGO:19035321280.014
mapk cascadeGO:00001651400.014
kidney mesenchyme developmentGO:007207420.014
cardiocyte differentiationGO:0035051220.014
positive regulation of mapk cascadeGO:0043410920.014
negative regulation of cell migration involved in sprouting angiogenesisGO:009005110.014
cell cell signalingGO:00072673350.014
response to metal ionGO:00100382530.014
single organism organelle organizationGO:19025891800.014
hepaticobiliary system developmentGO:0061008900.014
response to bacteriumGO:00096172000.014
regulation of heart contractionGO:0008016480.014
cation transmembrane transportGO:00986552630.014
smooth muscle cell proliferationGO:0048659770.014
negative regulation of cellular protein metabolic processGO:00322691060.014
sensory perception of painGO:0019233730.014
positive regulation of myeloid cell differentiationGO:004563970.014
anion transmembrane transportGO:0098656770.014
maintenance of locationGO:0051235170.014
stem cell differentiationGO:0048863160.014
forebrain developmentGO:0030900980.014
cell cell signaling involved in cell fate commitmentGO:004516820.014
neuronal stem cell maintenanceGO:009715020.013
carbohydrate derivative biosynthetic processGO:19011371240.013
defense responseGO:00069521940.013
cell migration involved in kidney developmentGO:003578720.013
regulation of protein serine threonine kinase activityGO:0071900640.013
metal ion homeostasisGO:00550651860.013
cellular component morphogenesisGO:00329891550.013
multicellular organism growthGO:003526410.013
lipid catabolic processGO:0016042460.013
negative regulation of phosphorus metabolic processGO:0010563800.013
regulation of peptide hormone secretionGO:0090276800.013
development of primary sexual characteristicsGO:00451371070.013
purine ribonucleotide biosynthetic processGO:0009152810.013
striated muscle cell developmentGO:0055002260.013
asymmetric stem cell divisionGO:009872220.013
female gonad developmentGO:0008585530.013
heart contractionGO:0060047570.013
lymphocyte migrationGO:007267630.013
regulation of peptide secretionGO:0002791820.013
ion homeostasisGO:00508012120.013
chlorinated hydrocarbon metabolic processGO:004219640.013
dna metabolic processGO:0006259960.013
negative regulation of chemotaxisGO:005092250.013
positive regulation of axon guidanceGO:190266930.013
male gonad developmentGO:0008584590.013
molting cycleGO:004230330.013
glycosyl compound metabolic processGO:19016571820.013

Kdr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.085
disease of anatomical entityDOID:700.085
kidney diseaseDOID:55700.085
cardiovascular system diseaseDOID:128700.047
nervous system diseaseDOID:86300.016
vascular diseaseDOID:17800.015
sensory system diseaseDOID:005015500.014
eye diseaseDOID:561400.014
retinal diseaseDOID:567900.014
eye and adnexa diseaseDOID:149200.014