Rattus norvegicus

101 known processes

Hsd3b6

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6

(Aliases: Hsd3b1,MGC109236)

Hsd3b6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to biotic stimulusGO:00096072260.685
regulation of programmed cell deathGO:00430673410.473
regulation of nucleic acid templated transcriptionGO:19035063800.448
regulation of transcription from rna polymerase ii promoterGO:00063572340.431
response to peptideGO:19016522920.392
Rat
circulatory system developmentGO:00723591340.379
regulation of transcription dna templatedGO:00063553740.370
response to other organismGO:00517072200.365
ion homeostasisGO:00508012120.357
homeostatic processGO:00425923310.323
Rat
cation homeostasisGO:00550801950.307
nucleic acid templated transcriptionGO:00976593790.306
multi multicellular organism processGO:00447061380.264
Rat
response to inorganic substanceGO:00100353770.246
cellular chemical homeostasisGO:00550822470.245
Rat
transcription dna templatedGO:00063513770.241
reproductive system developmentGO:00614581280.239
rna biosynthetic processGO:00327743800.232
organ regenerationGO:00311001010.227
cellular response to stressGO:00335542690.225
Rat
regulation of cell proliferationGO:00421273590.212
regenerationGO:00310991630.210
inorganic cation transmembrane transportGO:00986622020.207
response to metal ionGO:00100382530.206
programmed cell deathGO:00125013920.204
secretionGO:00469033070.199
response to external biotic stimulusGO:00432072210.199
locomotionGO:00400112370.195
transcription from rna polymerase ii promoterGO:00063662520.194
lipid biosynthetic processGO:00086101280.193
circulatory system processGO:00030131830.191
cation transmembrane transportGO:00986552630.190
cell cell signalingGO:00072673350.189
negative regulation of transcription dna templatedGO:00458921160.182
regulation of rna metabolic processGO:00512523910.181
cellular cation homeostasisGO:00300031800.177
multicellular organism reproductionGO:00325042330.176
Rat
negative regulation of gene expressionGO:00106291990.174
neuron projection developmentGO:00311752730.172
lipid metabolic processGO:00066292830.169
rna metabolic processGO:00160704060.164
negative regulation of rna metabolic processGO:00512531230.160
response to lipopolysaccharideGO:00324961910.156
positive regulation of gene expressionGO:00106282440.155
negative regulation of multicellular organismal processGO:00512412030.150
negative regulation of rna biosynthetic processGO:19026791180.150
metal ion transportGO:00300012890.149
negative regulation of nitrogen compound metabolic processGO:00511721610.149
reproductionGO:00000032450.147
Rat
cellular ketone metabolic processGO:0042180510.147
Rat
secretion by cellGO:00329402480.142
inorganic ion transmembrane transportGO:00986602290.142
positive regulation of multicellular organismal processGO:00512403870.139
protein complex biogenesisGO:00702712630.139
cellular response to hormone stimulusGO:00328702470.138
Rat
g protein coupled receptor signaling pathwayGO:00071862420.138
regulation of secretion by cellGO:19035302080.135
negative regulation of macromolecule biosynthetic processGO:00105581480.132
nitrogen compound transportGO:00717052290.132
cellular lipid metabolic processGO:00442552080.124
Rat
response to woundingGO:00096112540.124
apoptotic processGO:00069153810.124
positive regulation of nucleobase containing compound metabolic processGO:00459353190.123
multi organism reproductive processGO:00447032620.121
Rat
negative regulation of nucleobase containing compound metabolic processGO:00459341530.120
negative regulation of nucleic acid templated transcriptionGO:19035071170.120
cellular divalent inorganic cation homeostasisGO:00725031620.117
negative regulation of apoptotic processGO:00430661810.114
response to peptide hormoneGO:00434342780.114
Rat
cardiovascular system developmentGO:00723581340.111
cell migrationGO:00164771970.111
blood circulationGO:00080151830.110
defense responseGO:00069521940.109
negative regulation of cellular metabolic processGO:00313242810.108
macromolecular complex subunit organizationGO:00439333390.106
response to decreased oxygen levelsGO:00362932370.106
growthGO:00400071650.105
positive regulation of nitrogen compound metabolic processGO:00511733340.103
regulation of blood pressureGO:0008217830.102
neuron differentiationGO:00301823680.101
female pregnancyGO:00075651220.101
Rat
regulation of ion transportGO:00432692450.101
regulation of cellular ketone metabolic processGO:0010565270.099
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.098
regulation of apoptotic processGO:00429813350.095
cellular homeostasisGO:00197252520.095
Rat
cellular component movementGO:00069282480.093
regulation of rna biosynthetic processGO:20011413810.092
cellular response to endogenous stimulusGO:00714953770.091
Rat
transmembrane transportGO:00550854120.090
regulation of system processGO:00440572080.089
regulation of cellular localizationGO:00603412630.088
neurological system processGO:00508772190.087
response to purine containing compoundGO:00140741260.087
Rat
regulation of cellular component biogenesisGO:0044087860.087
cellular ion homeostasisGO:00068731840.087
response to bacteriumGO:00096172000.087
reproductive structure developmentGO:00486081280.086
cellular calcium ion homeostasisGO:00068741600.082
response to molecule of bacterial originGO:00022371940.080
negative regulation of macromolecule metabolic processGO:00106052600.080
localization of cellGO:00516742020.078
positive regulation of blood circulationGO:1903524650.075
regulation of cellular component organizationGO:00511283680.075
negative regulation of transportGO:00510511360.074
oxoacid metabolic processGO:00434362900.073
regulation of blood circulationGO:19035221100.072
regulation of vasoconstrictionGO:0019229440.072
single organism reproductive processGO:00447022970.072
negative regulation of metabolic processGO:00098923310.071
response to nicotineGO:0035094510.070
response to estrogenGO:00436272320.070
Rat
regulation of blood vessel sizeGO:0050880890.070
chemical homeostasisGO:00488782920.070
Rat
response to alkaloidGO:00432791320.069
Rat
negative regulation of cellular biosynthetic processGO:00313271610.067
cellular response to acid chemicalGO:0071229750.067
positive regulation of cell proliferationGO:00082842490.066
metal ion homeostasisGO:00550651860.066
regulation of secretionGO:00510462240.065
cell motilityGO:00488702020.065
cellular component assemblyGO:00226073600.065
regulation of multicellular organismal developmentGO:20000263760.065
cellular response to oxidative stressGO:0034599760.064
Rat
carboxylic acid metabolic processGO:00197522890.063
response to retinoic acidGO:0032526630.063
cell projection organizationGO:00300303020.063
regulation of cell projection organizationGO:00313441750.063
sex differentiationGO:00075481130.062
regulation of hormone levelsGO:00108171870.061
multicellular organismal reproductive processGO:00486092330.061
Rat
positive regulation of signalingGO:00230562700.061
response to mineralocorticoidGO:0051385490.060
positive regulation of rna biosynthetic processGO:19026801970.060
vascular process in circulatory systemGO:0003018960.060
protein complex subunit organizationGO:00718223020.059
developmental process involved in reproductionGO:00030061590.059
proteolysisGO:00065081750.059
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.058
monovalent inorganic cation transportGO:00156721720.057
single organism behaviorGO:00447081300.056
cell morphogenesis involved in differentiationGO:00009041190.056
regulation of neuron projection developmentGO:00109751610.056
reproductive processGO:00224143720.056
ion transmembrane transportGO:00342203650.055
cation transportGO:00068123820.054
single organism biosynthetic processGO:00447113420.053
regulation of tube sizeGO:0035150890.053
sodium ion transportGO:0006814820.052
inflammatory responseGO:00069541500.052
response to glucocorticoidGO:00513842230.051
response to extracellular stimulusGO:00099913800.051
Rat
lipid localizationGO:0010876620.050
response to acid chemicalGO:00011012220.050
Rat
cell morphogenesis involved in neuron differentiationGO:00486671060.049
cellular component biogenesisGO:00440853680.049
macromolecule localizationGO:00330362520.049
negative regulation of cell deathGO:00605482290.049
macromolecular complex assemblyGO:00650032730.049
response to estradiolGO:00323551640.048
Rat
small molecule biosynthetic processGO:00442831240.048
Rat
intracellular signal transductionGO:00355563140.048
central nervous system developmentGO:00074173110.047
gonad developmentGO:00084061040.046
organic acid metabolic processGO:00060822920.046
Rat
neuropeptide signaling pathwayGO:0007218290.046
epithelium developmentGO:0060429960.046
lipid transportGO:0006869610.046
ovulation cycle processGO:0022602500.046
response to reactive oxygen speciesGO:00003021200.045
Rat
positive regulation of biosynthetic processGO:00098913190.045
positive regulation of nucleic acid templated transcriptionGO:19035081970.045
negative regulation of developmental processGO:00510931250.045
sensory perception of painGO:0019233730.043
positive regulation of rna metabolic processGO:00512542030.043
cellular amine metabolic processGO:0044106380.043
Rat
response to organophosphorusGO:00466831020.042
Rat
renal sodium excretionGO:0035812200.041
regulation of cell migrationGO:00303341280.041
endocrine system developmentGO:0035270300.041
Rat
regulation of neurogenesisGO:00507672470.040
protein processingGO:0016485680.040
protein localizationGO:00081041910.040
response to ethanolGO:00454711620.040
Rat
regulation of peptide transportGO:0090087870.040
positive regulation of cell communicationGO:00106472710.040
carbohydrate derivative metabolic processGO:19011353460.039
positive regulation of developmental processGO:00510942830.039
leydig cell differentiationGO:003332780.038
protein maturationGO:0051604680.038
positive regulation of macromolecule biosynthetic processGO:00105572470.038
neuron developmentGO:00486662860.038
positive regulation of apoptotic processGO:00430651540.037
feeding behaviorGO:0007631530.037
response to nutrientGO:00075842480.037
Rat
positive regulation of cellular biosynthetic processGO:00313282950.037
positive regulation of transcription dna templatedGO:00458931970.036
placenta developmentGO:0001890220.036
positive regulation of response to stimulusGO:00485842850.035
immune system processGO:00023762040.035
Rat
regulation of membrane potentialGO:00423911100.035
negative regulation of biosynthetic processGO:00098901680.035
regulation of systemic arterial blood pressureGO:0003073300.035
regulation of cellular amine metabolic processGO:003323880.035
calcium ion transportGO:00068161310.034
regulation of neurological system processGO:0031644430.034
calcium ion homeostasisGO:00550741620.033
negative regulation of programmed cell deathGO:00430691830.033
synaptic transmissionGO:00072682350.033
regulation of ion homeostasisGO:2000021630.033
regulation of body fluid levelsGO:0050878900.033
response to corticosteroidGO:00319602350.033
positive regulation of secretion by cellGO:19035321280.032
behaviorGO:00076102050.032
cellular response to oxygen containing compoundGO:19017013860.032
Rat
cellular response to metal ionGO:0071248550.031
Rat
female sex differentiationGO:0046660590.031
Rat
agingGO:00075682410.031
regulation of renal sodium excretionGO:0035813200.031
response to corticosteroneGO:0051412400.031
positive regulation of signal transductionGO:00099671750.031
response to oxygen levelsGO:00704822650.031
sensory perceptionGO:00076001010.031
regulation of cell differentiationGO:00455953200.030
limb morphogenesisGO:003510840.030
maternal process involved in female pregnancyGO:0060135380.030
Rat
regulation of response to woundingGO:1903034690.030
amine metabolic processGO:0009308380.029
Rat
organonitrogen compound biosynthetic processGO:19015661670.029
response to transition metal nanoparticleGO:19902671220.029
Rat
positive regulation of hormone secretionGO:0046887650.028
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.028
regulation of synaptic transmissionGO:00508041410.028
cell projection morphogenesisGO:00488581230.028
cellular metal ion homeostasisGO:00068751720.028
response to foodGO:0032094270.028
carboxylic acid transportGO:00469421150.027
carboxylic acid biosynthetic processGO:0046394830.027
cellular response to retinoic acidGO:0071300270.027
response to activityGO:0014823730.027
Rat
response to oxidative stressGO:00069791860.027
Rat
protein oligomerizationGO:00512591910.027
organ inductionGO:000175910.027
organophosphate biosynthetic processGO:00904071430.026
peptide secretionGO:0002790860.026
muscle cell proliferationGO:0033002840.026
cell activationGO:0001775970.026
cellular response to growth factor stimulusGO:00713631620.026
Rat
regulation of dna metabolic processGO:0051052600.026
positive regulation of secretionGO:00510471400.026
divalent inorganic cation transportGO:00725111340.025
positive regulation of cell motilityGO:2000147970.025
regulation of nervous system developmentGO:00519602640.025
male sex differentiationGO:0046661640.025
response to hypoxiaGO:00016662310.025
vasoconstrictionGO:0042310540.025
divalent metal ion transportGO:00708381320.025
hormone secretionGO:00468791150.024
axon developmentGO:0061564960.024
positive regulation of nervous system developmentGO:00519621780.024
dna metabolic processGO:0006259960.023
cellular amino acid metabolic processGO:00065201070.023
micturitionGO:006007340.023
cellular response to lipidGO:00713962010.023
Rat
regulation of protein maturationGO:1903317500.023
regulation of response to external stimulusGO:00321011060.023
monocarboxylic acid metabolic processGO:00327871520.023
regulation of metal ion transportGO:00109591180.023
action potentialGO:0001508540.022
protein complex assemblyGO:00064612630.022
multicellular organismal response to stressGO:0033555250.022
regulation of epithelial cell proliferationGO:0050678490.022
response to mechanical stimulusGO:00096121340.022
regulation of canonical wnt signaling pathwayGO:006082840.022
signal releaseGO:00230611450.022
organic anion transportGO:00157111320.022
regulation of cell motilityGO:20001451310.022
positive regulation of cellular amine metabolic processGO:003324030.022
positive regulation of programmed cell deathGO:00430681570.022
response to osmotic stressGO:0006970420.022
organic acid transportGO:00158491160.021
regulation of signal transductionGO:00099663180.021
regulation of protein localizationGO:0032880810.021
dicarboxylic acid transportGO:0006835340.021
negative regulation of cell proliferationGO:00082851190.021
negative regulation of blood pressureGO:0045776290.021
regulation of insulin secretionGO:0050796650.020
regulation of response to stressGO:00801341260.020
regulation of hydrolase activityGO:00513361430.020
positive regulation of transportGO:00510502450.020
neuron neuron synaptic transmissionGO:0007270600.020
regulation of peptide secretionGO:0002791820.020
regulation of growthGO:00400081050.020
immune responseGO:00069551040.020
vasculature developmentGO:0001944700.020
digestive system developmentGO:0055123410.020
organic hydroxy compound biosynthetic processGO:1901617510.020
Rat
insulin secretionGO:0030073690.020
regulation of protein metabolic processGO:00512462890.020
response to axon injuryGO:0048678590.020
phasic smooth muscle contractionGO:001482130.020
organic acid biosynthetic processGO:0016053830.020
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.020
response to nutrient levelsGO:00316673700.019
Rat
smooth muscle cell proliferationGO:0048659770.019
gamete generationGO:00072761240.019
Rat
development of primary female sexual characteristicsGO:0046545560.019
Rat
tissue developmentGO:00098882520.019
hormone transportGO:00099141210.019
female gonad developmentGO:0008585530.019
Rat
response to ketoneGO:19016541820.018
cytoplasmic transportGO:00164821150.018
steroid metabolic processGO:0008202730.018
organelle organizationGO:00069962660.018
regulation of molecular functionGO:00650093980.018
regulation of cellular amino acid metabolic processGO:000652120.018
amide transportGO:00428861050.018
positive regulation of fat cell proliferationGO:007034610.018
response to campGO:0051591910.018
Rat
negative regulation of response to stimulusGO:00485851550.018
regulation of catalytic activityGO:00507903040.018
heart developmentGO:0007507720.018
positive regulation of cellular component organizationGO:00511302000.018
single organism intracellular transportGO:19025821660.018
regulation of locomotionGO:00400121480.018
cell part morphogenesisGO:00329901230.018
negative regulation of signalingGO:00230571570.018
regulation of immune system processGO:00026821230.017
divalent inorganic cation homeostasisGO:00725071650.017
fatty acid metabolic processGO:0006631990.017
smooth muscle cell migrationGO:0014909360.017
axon regenerationGO:0031103280.017
excretionGO:0007588240.017
cellular response to organic cyclic compoundGO:00714072020.017
Rat
rhythmic processGO:00485111560.017
sexual reproductionGO:00199531480.017
Rat
protein homooligomerizationGO:0051260910.017
positive regulation of humoral immune responseGO:000292220.017
anion transportGO:00068201780.016
regulation of homeostatic processGO:00328441010.016
regulation of peptide hormone secretionGO:0090276800.016
monovalent inorganic cation homeostasisGO:0055067360.016
positive regulation of cellular component biogenesisGO:0044089550.016
amino acid transportGO:0006865700.016
response to glucoseGO:00097491360.016
Rat
renal system processGO:0003014400.016
negative regulation of cell communicationGO:00106481580.016
acute inflammatory responseGO:0002526580.016
positive regulation of neuron differentiationGO:00456661260.016
cellular macromolecule localizationGO:00707271220.016
regulation of anatomical structure morphogenesisGO:00226031410.016
axon ensheathmentGO:0008366400.016
regulation of cellular protein metabolic processGO:00322682670.016
negative regulation of ion transportGO:0043271510.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
angiotensin mediated drinking behaviorGO:000305120.016
monocarboxylic acid biosynthetic processGO:0072330480.016
positive regulation of ion transportGO:0043270940.016
regulation of smooth muscle cell proliferationGO:0048660750.015
positive regulation of catalytic activityGO:00430851840.015
ras protein signal transductionGO:0007265290.015
organic hydroxy compound transportGO:0015850770.015
regulation of acute inflammatory responseGO:0002673230.015
positive regulation of immune system processGO:0002684900.015
potassium ion transmembrane transportGO:0071805710.015
reactive nitrogen species metabolic processGO:200105710.015
hormone metabolic processGO:0042445690.015
dendrite developmentGO:0016358720.015
cellular response to fluid shear stressGO:007149840.015
positive regulation of cell deathGO:00109421840.015
sodium ion transmembrane transportGO:0035725670.014
positive regulation of action potentialGO:004576080.014
response to hydrogen peroxideGO:0042542890.014
Rat
regulation of transmembrane transportGO:00347621220.014
glycerolipid metabolic processGO:0046486670.014
Rat
regulation of protein modification processGO:00313991940.014
response to herbicideGO:0009635160.014
Rat
membrane organizationGO:0061024940.014
positive regulation of homeostatic processGO:0032846490.014
reactive oxygen species metabolic processGO:0072593370.014
glucose homeostasisGO:0042593750.014
Rat
neuron projection regenerationGO:0031102350.014
positive regulation of neurogenesisGO:00507691650.014
regulation of organic acid transportGO:0032890350.014
developmental inductionGO:003112820.014
muscle system processGO:00030121150.014
cellular response to organonitrogen compoundGO:00714171970.014
Rat
positive regulation of neuron projection developmentGO:0010976990.014
regulation of anatomical structure sizeGO:00900661350.014
potassium ion transportGO:0006813970.014
regulation of cellular component movementGO:00512701500.014
cellular catabolic processGO:00442482950.013
defense response to gram negative bacteriumGO:005082930.013
synaptic transmission cholinergicGO:0007271110.013
catabolic processGO:00090563510.013
regulation of sodium ion transmembrane transporter activityGO:200064940.013
ovulation cycleGO:0042698670.013
positive regulation of cell migrationGO:0030335960.013
response to cytokineGO:00340972150.013
positive regulation of cell projection organizationGO:00313461110.013
gliogenesisGO:0042063930.013
epidermis developmentGO:0008544110.013
development of primary male sexual characteristicsGO:0046546590.013
cellular potassium ion transportGO:0071804720.013
behavioral response to nicotineGO:003509520.013
smooth muscle contraction involved in micturitionGO:006008310.013
positive regulation of protein metabolic processGO:00512471780.012
positive regulation of synaptic transmission gabaergicGO:003223090.012
anatomical structure homeostasisGO:0060249290.012
regulation of cell growthGO:0001558850.012
cytosolic calcium ion homeostasisGO:00514801400.012
taxisGO:0042330670.012
response to calcium ionGO:0051592590.012
Rat
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.012
response to starvationGO:0042594590.012
regulation of calcium ion transportGO:0051924770.012
sodium ion homeostasisGO:0055078230.012
positive regulation of dna metabolic processGO:0051054390.012
single organism cellular localizationGO:19025801020.012
chemotaxisGO:0006935660.012
isoprenoid metabolic processGO:0006720450.012
Rat
regulation of hormone secretionGO:00468831060.012
positive regulation of response to woundingGO:1903036340.012
positive regulation of peptide secretionGO:0002793520.012
cellular response to lipopolysaccharideGO:0071222550.012
circadian rhythmGO:0007623880.012
acid secretionGO:0046717480.012
multicellular organismal signalingGO:0035637440.012
ribose phosphate metabolic processGO:00196932350.012
response to growth factorGO:00708481890.012
Rat
diterpenoid metabolic processGO:0016101330.012
Rat
regulation of organ formationGO:000315620.012
negative regulation of peptidase activityGO:0010466380.012
developmental growthGO:00485891000.012
gland developmentGO:00487321550.012
Rat
negative regulation of secretionGO:0051048820.011
peptide transportGO:0015833970.011
negative regulation of molecular functionGO:00440921330.011
odontogenesisGO:0042476320.011
digestive tract developmentGO:0048565390.011
response to fatty acidGO:0070542650.011
Rat
positive regulation of cell developmentGO:00107201760.011
axis specificationGO:000979840.011
regulation of protein phosphorylationGO:00019321830.011
positive regulation of cellular component movementGO:00512721020.011
cellular response to nitrogen compoundGO:19016992100.011
Rat
neuron deathGO:00709971270.011
mononuclear cell proliferationGO:0032943290.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
regulation of cell developmentGO:00602842630.011
positive regulation of intracellular signal transductionGO:19025331380.011
spermatogenesisGO:0007283990.011
sensory perception of bitter tasteGO:005091340.011
circadian regulation of gene expressionGO:003292230.011
keratinocyte differentiationGO:003021620.011
negative regulation of secretion by cellGO:1903531720.011
negative regulation of catalytic activityGO:00430861030.011
brain developmentGO:00074202470.011
regulation of protein processingGO:0070613500.011
regulation of feeding behaviorGO:0060259140.011
purine containing compound metabolic processGO:00725212530.011
negative regulation of protein maturationGO:1903318470.011
positive regulation of cardiac muscle cell proliferationGO:006004540.010
cellular response to abiotic stimulusGO:0071214850.010
tissue homeostasisGO:0001894280.010
calcium ion transport into cytosolGO:0060402380.010
sulfur compound metabolic processGO:0006790700.010
tissue remodelingGO:0048771400.010
negative regulation of cellular protein metabolic processGO:00322691060.010
neuron projection morphogenesisGO:00488121220.010
hair follicle developmentGO:000194220.010
somatostatin receptor signaling pathwayGO:003816940.010
regulation of defense responseGO:0031347680.010
wound healingGO:00420601220.010
carbohydrate metabolic processGO:00059751300.010
anatomical structure morphogenesisGO:00096532980.010
establishment of synaptic specificity at neuromuscular junctionGO:000752910.010
gastrulationGO:000736920.010

Hsd3b6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.027
Human
nervous system diseaseDOID:86300.014
disease of anatomical entityDOID:700.014
sensory system diseaseDOID:005015500.014
disease of cellular proliferationDOID:1456600.014
inherited metabolic disorderDOID:65500.011
Human
central nervous system diseaseDOID:33100.010