Rattus norvegicus

0 known processes

Slc12a4

solute carrier family 12 (potassium/chloride transporters), member 4

(Aliases: Kcc1)

Slc12a4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of phosphorus metabolic processGO:00511743490.347
cell motilityGO:00488702020.330
regulation of signal transductionGO:00099663180.231
cell migrationGO:00164771970.211
macromolecule localizationGO:00330362520.207
protein localizationGO:00081041910.191
locomotionGO:00400112370.182
regulation of cellular localizationGO:00603412630.177
localization of cellGO:00516742020.177
positive regulation of phosphorus metabolic processGO:00105622620.175
regulation of catalytic activityGO:00507903040.173
intracellular signal transductionGO:00355563140.166
regulation of apoptotic processGO:00429813350.157
regulation of cellular protein metabolic processGO:00322682670.156
regulation of phosphorylationGO:00423252480.152
positive regulation of phosphate metabolic processGO:00459372620.152
response to hypoxiaGO:00016662310.142
anatomical structure morphogenesisGO:00096532980.140
cellular component movementGO:00069282480.139
nucleic acid templated transcriptionGO:00976593790.138
apoptotic processGO:00069153810.131
regulation of multicellular organismal developmentGO:20000263760.131
protein phosphorylationGO:00064683450.131
positive regulation of cell communicationGO:00106472710.128
regulation of molecular functionGO:00650093980.124
response to extracellular stimulusGO:00099913800.117
catabolic processGO:00090563510.115
regulation of cell migrationGO:00303341280.115
negative regulation of programmed cell deathGO:00430691830.114
biological adhesionGO:00226101100.112
response to growth factorGO:00708481890.109
tissue developmentGO:00098882520.108
response to other organismGO:00517072200.107
response to nutrient levelsGO:00316673700.106
regulation of phosphate metabolic processGO:00192203490.105
regulation of protein metabolic processGO:00512462890.105
rna metabolic processGO:00160704060.103
positive regulation of developmental processGO:00510942830.102
regulation of cellular component organizationGO:00511283680.101
regulation of programmed cell deathGO:00430673410.099
macromolecular complex subunit organizationGO:00439333390.098
regulation of transferase activityGO:00513381230.097
cation transportGO:00068123820.097
Rat
cellular component assemblyGO:00226073600.096
response to oxygen levelsGO:00704822650.095
secretionGO:00469033070.093
regulation of rna metabolic processGO:00512523910.091
programmed cell deathGO:00125013920.091
regulation of secretionGO:00510462240.091
carbohydrate derivative metabolic processGO:19011353460.091
positive regulation of nitrogen compound metabolic processGO:00511733340.089
negative regulation of metabolic processGO:00098923310.089
response to decreased oxygen levelsGO:00362932370.089
actin filament based processGO:0030029860.086
negative regulation of cell deathGO:00605482290.084
protein transportGO:00150311320.084
mesoderm developmentGO:000749820.082
positive regulation of response to stimulusGO:00485842850.082
carboxylic acid metabolic processGO:00197522890.081
positive regulation of cell motilityGO:2000147970.081
cellular component biogenesisGO:00440853680.081
regulation of secretion by cellGO:19035302080.080
tissue morphogenesisGO:0048729220.079
cell projection organizationGO:00300303020.078
positive regulation of signal transductionGO:00099671750.078
purine containing compound metabolic processGO:00725212530.078
ribose phosphate metabolic processGO:00196932350.077
regulation of rna biosynthetic processGO:20011413810.077
rna biosynthetic processGO:00327743800.077
positive regulation of cellular protein metabolic processGO:00322701670.077
regulation of nervous system developmentGO:00519602640.076
secretion by cellGO:00329402480.076
positive regulation of phosphorylationGO:00423271770.076
protein complex subunit organizationGO:00718223020.076
neurological system processGO:00508772190.076
ribonucleoside triphosphate catabolic processGO:00092031220.076
response to external biotic stimulusGO:00432072210.075
cell activationGO:0001775970.075
establishment of protein localizationGO:00451841410.075
signal transduction by phosphorylationGO:00230141440.074
positive regulation of multicellular organismal processGO:00512403870.072
single organism organelle organizationGO:19025891800.071
cellular response to hormone stimulusGO:00328702470.071
negative regulation of response to stimulusGO:00485851550.070
cellular amino acid metabolic processGO:00065201070.069
organelle organizationGO:00069962660.069
negative regulation of cellular metabolic processGO:00313242810.069
oxoacid metabolic processGO:00434362900.069
organic acid metabolic processGO:00060822920.068
homeostatic processGO:00425923310.068
Rat
positive regulation of cell differentiationGO:00455972170.067
regulation of neuron differentiationGO:00456642080.066
positive regulation of nucleobase containing compound metabolic processGO:00459353190.066
regulation of intracellular signal transductionGO:19025312180.065
response to cytokineGO:00340972150.065
behaviorGO:00076102050.064
purine nucleotide metabolic processGO:00061632290.064
positive regulation of gene expressionGO:00106282440.064
regulation of protein modification processGO:00313991940.063
negative regulation of cell communicationGO:00106481580.063
positive regulation of cellular biosynthetic processGO:00313282950.063
cell cycleGO:00070491010.062
cellular catabolic processGO:00442482950.061
multicellular organism reproductionGO:00325042330.061
regulation of protein localizationGO:0032880810.061
regulation of locomotionGO:00400121480.061
positive regulation of molecular functionGO:00440932300.061
purine nucleoside catabolic processGO:00061521240.060
regulation of nucleic acid templated transcriptionGO:19035063800.060
peptidyl amino acid modificationGO:00181931260.060
positive regulation of intracellular signal transductionGO:19025331380.060
negative regulation of apoptotic processGO:00430661810.059
ribonucleoside catabolic processGO:00424541260.059
gastrulationGO:000736920.059
cell morphogenesis involved in neuron differentiationGO:00486671060.058
regulation of neurogenesisGO:00507672470.058
response to peptide hormoneGO:00434342780.058
ribonucleotide catabolic processGO:00092611360.057
multicellular organismal reproductive processGO:00486092330.057
response to bacteriumGO:00096172000.057
transcription dna templatedGO:00063513770.057
regulation of cellular component movementGO:00512701500.057
cardiovascular system developmentGO:00723581340.057
positive regulation of biosynthetic processGO:00098913190.056
single organism catabolic processGO:00447122830.056
positive regulation of signalingGO:00230562700.056
purine ribonucleotide catabolic processGO:00091541360.056
positive regulation of cell migrationGO:0030335960.056
reproductionGO:00000032450.055
regulation of anatomical structure morphogenesisGO:00226031410.055
positive regulation of protein phosphorylationGO:00019341350.054
defense responseGO:00069521940.053
amine metabolic processGO:0009308380.053
organophosphate metabolic processGO:00196373700.053
regulation of cellular amine metabolic processGO:003323880.053
regulation of hydrolase activityGO:00513361430.053
organonitrogen compound catabolic processGO:19015651790.053
cellular response to oxygen containing compoundGO:19017013860.053
purine ribonucleoside catabolic processGO:00461301240.053
purine ribonucleotide metabolic processGO:00091502270.053
wound healingGO:00420601220.053
positive regulation of neurogenesisGO:00507691650.053
positive regulation of cell developmentGO:00107201760.052
organophosphate catabolic processGO:00464341480.052
response to woundingGO:00096112540.052
positive regulation of cellular component movementGO:00512721020.052
regulation of ion transportGO:00432692450.052
positive regulation of cell deathGO:00109421840.052
organic substance catabolic processGO:19015753160.052
regulation of protein phosphorylationGO:00019321830.051
positive regulation of catalytic activityGO:00430851840.051
nucleotide metabolic processGO:00091172790.051
response to inorganic substanceGO:00100353770.051
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.051
transmission of nerve impulseGO:0019226420.050
reproductive processGO:00224143720.050
cellular chemical homeostasisGO:00550822470.049
Rat
positive regulation of nervous system developmentGO:00519621780.049
cytoskeleton organizationGO:00070101110.049
cell cell signalingGO:00072673350.049
positive regulation of protein modification processGO:00314011420.049
regulation of cell proliferationGO:00421273590.049
response to metal ionGO:00100382530.049
cellular amine metabolic processGO:0044106380.049
regulation of cellular ketone metabolic processGO:0010565270.048
response to vitaminGO:00332731310.048
response to biotic stimulusGO:00096072260.048
cellular response to endogenous stimulusGO:00714953770.047
protein importGO:0017038370.047
regulation of kinase activityGO:00435491170.047
regulation of cellular amino acid metabolic processGO:000652120.047
limb morphogenesisGO:003510840.046
agingGO:00075682410.046
multi organism reproductive processGO:00447032620.045
connective tissue developmentGO:0061448330.045
enzyme linked receptor protein signaling pathwayGO:00071671160.045
nucleoside catabolic processGO:00091641260.044
negative regulation of multicellular organismal processGO:00512412030.044
positive regulation of macromolecule biosynthetic processGO:00105572470.044
aromatic compound catabolic processGO:00194391680.044
defense response to other organismGO:0098542170.044
growthGO:00400071650.044
ribonucleotide metabolic processGO:00092592310.044
purine nucleotide catabolic processGO:00061951360.043
cellular response to stressGO:00335542690.043
nucleobase containing small molecule metabolic processGO:00550863160.043
proteolysisGO:00065081750.043
central nervous system developmentGO:00074173110.043
epithelium developmentGO:0060429960.043
regulation of cell motilityGO:20001451310.043
regulation of cell differentiationGO:00455953200.043
chemical homeostasisGO:00488782920.042
Rat
single organism intracellular transportGO:19025821660.042
protein complex assemblyGO:00064612630.042
circulatory system processGO:00030131830.042
positive regulation of cellular component organizationGO:00511302000.041
membrane organizationGO:0061024940.041
positive regulation of apoptotic processGO:00430651540.041
purine ribonucleoside triphosphate catabolic processGO:00092071220.041
carbohydrate derivative catabolic processGO:19011361470.041
organ morphogenesisGO:0009887750.040
purine nucleoside triphosphate metabolic processGO:00091441410.040
positive regulation of rna biosynthetic processGO:19026801970.040
mechanoreceptor differentiationGO:004249020.040
ribonucleoside metabolic processGO:00091191740.040
negative regulation of signalingGO:00230571570.039
regulation of protein transportGO:0051223680.039
g protein coupled receptor signaling pathwayGO:00071862420.039
multicellular organismal signalingGO:0035637440.039
regulation of cell morphogenesis involved in differentiationGO:0010769720.039
nucleoside phosphate metabolic processGO:00067532830.039
protein secretionGO:0009306340.039
cellular ketone metabolic processGO:0042180510.039
positive regulation of transcription dna templatedGO:00458931970.038
negative regulation of nervous system developmentGO:0051961790.038
gland developmentGO:00487321550.038
positive regulation of programmed cell deathGO:00430681570.038
response to carbohydrateGO:00097431830.038
positive regulation of kinase activityGO:0033674770.038
single organism reproductive processGO:00447022970.038
heterocycle catabolic processGO:00467001670.037
actin cytoskeleton organizationGO:0030036730.037
regulation of catabolic processGO:00098941130.037
positive regulation of protein metabolic processGO:00512471780.037
nucleobase containing compound catabolic processGO:00346551520.037
regulation of purine nucleotide metabolic processGO:19005421150.036
organic cyclic compound catabolic processGO:19013611750.036
small gtpase mediated signal transductionGO:0007264360.036
sexual reproductionGO:00199531480.036
purine ribonucleoside metabolic processGO:00461281680.036
positive regulation of cell projection organizationGO:00313461110.036
cellular homeostasisGO:00197252520.036
Rat
lipid metabolic processGO:00066292830.035
glycosyl compound catabolic processGO:19016581260.035
cation transmembrane transportGO:00986552630.035
Rat
purine ribonucleoside triphosphate metabolic processGO:00092051400.035
blood circulationGO:00080151830.034
positive regulation of locomotionGO:00400171020.034
negative regulation of cellular component organizationGO:0051129830.034
regulation of cell morphogenesisGO:0022604770.034
macromolecular complex assemblyGO:00650032730.034
nucleoside metabolic processGO:00091161790.034
protein complex biogenesisGO:00702712630.034
muscle structure developmentGO:0061061870.034
embryonic appendage morphogenesisGO:003511340.033
transcription from rna polymerase ii promoterGO:00063662520.033
positive regulation of rna metabolic processGO:00512542030.033
regulation of cell projection organizationGO:00313441750.033
positive regulation of purine nucleotide metabolic processGO:1900544910.033
mapk cascadeGO:00001651400.033
cell adhesionGO:00071551100.033
single organism biosynthetic processGO:00447113420.033
negative regulation of phosphorus metabolic processGO:0010563800.033
muscle system processGO:00030121150.033
positive regulation of mapk cascadeGO:0043410920.032
nucleoside phosphate catabolic processGO:19012921400.032
positive regulation of cellular amino acid metabolic processGO:004576410.032
heart processGO:0003015570.032
heart morphogenesisGO:000300730.032
positive regulation of neuron differentiationGO:00456661260.032
endocytosisGO:0006897840.032
protein oligomerizationGO:00512591910.032
nucleoside triphosphate metabolic processGO:00091411440.031
regulation of protein kinase activityGO:00458591050.031
response to organophosphorusGO:00466831020.031
head developmentGO:00603222470.031
neuron differentiationGO:00301823680.031
regulation of system processGO:00440572080.031
regenerationGO:00310991630.031
nucleotide catabolic processGO:00091661390.031
negative regulation of nucleobase containing compound metabolic processGO:00459341530.031
positive regulation of nucleotide metabolic processGO:0045981910.031
cellular response to cytokine stimulusGO:00713451270.031
cellular response to growth factor stimulusGO:00713631620.031
circulatory system developmentGO:00723591340.031
negative regulation of cell differentiationGO:0045596990.031
divalent metal ion transportGO:00708381320.031
vesicle mediated transportGO:00161921810.031
positive regulation of protein serine threonine kinase activityGO:0071902520.030
regulation of transcription dna templatedGO:00063553740.030
purine nucleoside metabolic processGO:00422781690.030
regulation of proteasomal protein catabolic processGO:006113640.030
urogenital system developmentGO:0001655780.030
cellular ion homeostasisGO:00068731840.029
Rat
cellular nitrogen compound catabolic processGO:00442701630.029
cell part morphogenesisGO:00329901230.029
lipid biosynthetic processGO:00086101280.029
inflammatory responseGO:00069541500.029
regulation of establishment of protein localizationGO:0070201690.029
cellular protein localizationGO:00346131220.029
response to nutrientGO:00075842480.029
regulation of membrane potentialGO:00423911100.029
angiogenesisGO:0001525530.029
positive regulation of transportGO:00510502450.028
cell projection morphogenesisGO:00488581230.028
neuron projection developmentGO:00311752730.028
neuron developmentGO:00486662860.028
response to molecule of bacterial originGO:00022371940.028
regulation of transcription from rna polymerase ii promoterGO:00063572340.028
positive regulation of cellular amine metabolic processGO:003324030.028
cellular component morphogenesisGO:00329891550.027
regulation of nucleotide catabolic processGO:0030811650.027
ion transmembrane transportGO:00342203650.027
Rat
ion homeostasisGO:00508012120.027
Rat
negative regulation of cellular protein metabolic processGO:00322691060.027
synaptic transmissionGO:00072682350.027
neuronal action potentialGO:0019228350.027
anterior posterior pattern specificationGO:000995210.027
response to peptideGO:19016522920.027
negative regulation of protein metabolic processGO:00512481140.027
anatomical structure formation involved in morphogenesisGO:0048646830.026
tissue regenerationGO:0042246360.026
blood vessel developmentGO:0001568690.026
regulation of mapk cascadeGO:00434081160.026
transmembrane transportGO:00550854120.026
Rat
negative regulation of developmental processGO:00510931250.026
apoptotic signaling pathwayGO:0097190270.026
metal ion homeostasisGO:00550651860.026
cell growthGO:00160491040.026
nucleoside triphosphate catabolic processGO:00091431230.026
positive regulation of cell proliferationGO:00082842490.025
response to amino acidGO:0043200750.025
divalent inorganic cation transportGO:00725111340.025
immune responseGO:00069551040.025
positive regulation of protein kinase activityGO:0045860730.025
developmental growthGO:00485891000.025
immune system processGO:00023762040.025
axon ensheathmentGO:0008366400.024
vascular process in circulatory systemGO:0003018960.024
intracellular transportGO:00469071850.024
reactive oxygen species metabolic processGO:0072593370.024
small molecule biosynthetic processGO:00442831240.024
regulation of cell developmentGO:00602842630.024
calcium ion transportGO:00068161310.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
negative regulation of molecular functionGO:00440921330.024
embryo developmentGO:0009790490.024
response to corticosteroidGO:00319602350.024
regulation of protein secretionGO:0050708280.024
muscle tissue developmentGO:0060537580.023
myelinationGO:0042552390.023
regulation of hormone levelsGO:00108171870.023
intracellular protein transportGO:0006886790.023
gamete generationGO:00072761240.023
ras protein signal transductionGO:0007265290.023
cellular divalent inorganic cation homeostasisGO:00725031620.023
cellular response to oxygen levelsGO:0071453600.023
brain developmentGO:00074202470.023
cognitionGO:0050890920.023
bmp signaling pathwayGO:003050940.022
protein targetingGO:0006605610.022
response to starvationGO:0042594590.022
muscle tissue morphogenesisGO:006041510.022
glycosyl compound metabolic processGO:19016571820.022
fatty acid metabolic processGO:0006631990.022
regulation of blood vessel sizeGO:0050880890.022
organonitrogen compound biosynthetic processGO:19015661670.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
negative regulation of macromolecule metabolic processGO:00106052600.022
calcium ion homeostasisGO:00550741620.022
response to monosaccharideGO:00342841590.022
cell morphogenesisGO:00009021420.022
glial cell differentiationGO:0010001650.022
response to acid chemicalGO:00011012220.022
negative regulation of rna biosynthetic processGO:19026791180.022
regulation of map kinase activityGO:0043405530.021
skin morphogenesisGO:004358920.021
response to lipopolysaccharideGO:00324961910.021
regulation of extrinsic apoptotic signaling pathwayGO:200123670.021
positive regulation of transferase activityGO:0051347810.021
monovalent inorganic cation transportGO:00156721720.021
Rat
formation of primary germ layerGO:000170410.021
negative regulation of gene expressionGO:00106291990.021
positive regulation of cytosolic calcium ion concentrationGO:00072041220.021
cellular macromolecule localizationGO:00707271220.021
regulation of cellular component biogenesisGO:0044087860.021
gliogenesisGO:0042063930.021
positive regulation of hydrolase activityGO:0051345860.021
regulation of tube sizeGO:0035150890.021
regulation of stem cell differentiationGO:200073620.021
regulation of anatomical structure sizeGO:00900661350.021
cellular cation homeostasisGO:00300031800.021
Rat
response to glucoseGO:00097491360.021
negative regulation of transportGO:00510511360.021
action potentialGO:0001508540.020
axon developmentGO:0061564960.020
negative regulation of signal transductionGO:0009968830.020
regulation of response to external stimulusGO:00321011060.020
cellular response to organonitrogen compoundGO:00714171970.020
regulation of cell cycleGO:0051726730.020
regulation of protein serine threonine kinase activityGO:0071900640.020
cytoplasmic transportGO:00164821150.020
cellular response to tumor necrosis factorGO:0071356460.020
cyclic nucleotide metabolic processGO:0009187800.020
regulation of cellular catabolic processGO:00313291010.020
cell morphogenesis involved in differentiationGO:00009041190.020
positive regulation of neuron projection developmentGO:0010976990.020
heart contractionGO:0060047570.020
cellular calcium ion homeostasisGO:00068741600.020
divalent inorganic cation homeostasisGO:00725071650.020
cell cycle processGO:0022402570.020
organophosphate biosynthetic processGO:00904071430.020
single organism membrane organizationGO:0044802740.020
chemotaxisGO:0006935660.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
muscle organ morphogenesisGO:004864410.020
positive regulation of protein transportGO:0051222410.020
single organism cellular localizationGO:19025801020.020
response to heatGO:0009408600.020
tube developmentGO:0035295890.020
neuron fate commitmentGO:004866340.020
reproductive system developmentGO:00614581280.019
learning or memoryGO:0007611900.019
regulation of nucleotide metabolic processGO:00061401170.019
ribonucleoside triphosphate metabolic processGO:00091991410.019
cellular metal ion homeostasisGO:00068751720.019
response to purine containing compoundGO:00140741260.019
negative regulation of neuron differentiationGO:0045665620.019
guanosine containing compound catabolic processGO:1901069710.019
digestive system developmentGO:0055123410.019
purine nucleoside triphosphate catabolic processGO:00091461220.019
negative regulation of catalytic activityGO:00430861030.018
regulation of growthGO:00400081050.018
response to estradiolGO:00323551640.018
regulation of immune system processGO:00026821230.018
vasculature developmentGO:0001944700.018
organ formationGO:004864530.018
embryonic limb morphogenesisGO:003032640.018
regulation of response to woundingGO:1903034690.018
neuron deathGO:00709971270.018
regulation of reactive oxygen species metabolic processGO:2000377260.018
female pregnancyGO:00075651220.018
response to hexoseGO:00097461440.018
response to temperature stimulusGO:0009266940.018
reproductive structure developmentGO:00486081280.018
purine containing compound catabolic processGO:00725231380.018
negative regulation of cell developmentGO:0010721820.018
inorganic cation transmembrane transportGO:00986622020.018
Rat
heart developmentGO:0007507720.018
cytosolic calcium ion homeostasisGO:00514801400.018
response to ketoneGO:19016541820.018
macromolecule catabolic processGO:0009057580.018
extrinsic apoptotic signaling pathwayGO:0097191100.017
appendage morphogenesisGO:003510740.017
endomembrane system organizationGO:0010256480.017
small molecule catabolic processGO:0044282590.017
hair cell differentiationGO:003531520.017
regulation of ossificationGO:0030278320.017
neuron projection morphogenesisGO:00488121220.017
developmental process involved in reproductionGO:00030061590.017
protein autophosphorylationGO:0046777660.017
cyclic nucleotide biosynthetic processGO:0009190630.017
oxidation reduction processGO:00551143040.017
protein heterooligomerizationGO:0051291890.017
peptidyl lysine hydroxylationGO:001718510.017
cell fate determinationGO:000170920.017
reactive oxygen species biosynthetic processGO:190340980.017
amide transportGO:00428861050.017
respiratory system developmentGO:0060541450.017
response to alkaloidGO:00432791320.017
forebrain developmentGO:0030900980.016
organic acid biosynthetic processGO:0016053830.016
embryonic pattern specificationGO:000988010.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
extracellular structure organizationGO:0043062130.016
embryonic cranial skeleton morphogenesisGO:004870120.016
blood vessel morphogenesisGO:0048514580.016
negative regulation of osteoblast differentiationGO:004566820.016
dna metabolic processGO:0006259960.016
regulation of muscle system processGO:0090257790.016
response to estrogenGO:00436272320.016
atp catabolic processGO:0006200540.016
lung developmentGO:0030324430.016
nucleocytoplasmic transportGO:0006913480.016
cytokine productionGO:0001816610.016
multi multicellular organism processGO:00447061380.016
male gamete generationGO:0048232990.016
positive regulation of secretionGO:00510471400.016

Slc12a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.454
musculoskeletal system diseaseDOID:1700.454
muscular diseaseDOID:008000000.207
myopathyDOID:42300.207
muscle tissue diseaseDOID:6600.207
muscular dystrophyDOID:988400.075
nervous system diseaseDOID:86300.074
cardiovascular system diseaseDOID:128700.069
connective tissue diseaseDOID:6500.042
bone development diseaseDOID:008000600.025
bone diseaseDOID:008000100.025
heart diseaseDOID:11400.023
cardiomyopathyDOID:005070000.023
sensory system diseaseDOID:005015500.022
neuromuscular diseaseDOID:44000.021
neuropathyDOID:87000.021
disease of metabolismDOID:001466700.019
intrinsic cardiomyopathyDOID:006003600.016