Rattus norvegicus

9 known processes

Slc12a7

solute carrier family 12 (potassium/chloride transporters), member 7

(Aliases: Kcc4)

Slc12a7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.089
cellular component biogenesisGO:00440853680.060
cellular amino acid metabolic processGO:00065201070.058
oxoacid metabolic processGO:00434362900.057
cellular component assemblyGO:00226073600.056
regulation of phosphate metabolic processGO:00192203490.052
macromolecular complex subunit organizationGO:00439333390.051
anatomical structure morphogenesisGO:00096532980.051
secretionGO:00469033070.050
cell communication involved in cardiac conductionGO:008606520.050
homeostatic processGO:00425923310.048
cellular response to endogenous stimulusGO:00714953770.048
regulation of phosphorus metabolic processGO:00511743490.047
organic acid metabolic processGO:00060822920.046
cell projection organizationGO:00300303020.045
protein phosphorylationGO:00064683450.045
carboxylic acid metabolic processGO:00197522890.043
positive regulation of multicellular organismal processGO:00512403870.043
regulation of cellular amine metabolic processGO:003323880.042
single organism biosynthetic processGO:00447113420.041
cardiac chamber developmentGO:000320510.040
blood circulationGO:00080151830.039
regulation of molecular functionGO:00650093980.039
regulation of membrane potentialGO:00423911100.039
circulatory system processGO:00030131830.039
regulation of catalytic activityGO:00507903040.039
regulation of transcription dna templatedGO:00063553740.038
macromolecule localizationGO:00330362520.038
positive regulation of nitrogen compound metabolic processGO:00511733340.038
regulation of cellular amino acid metabolic processGO:000652120.035
cation transportGO:00068123820.035
Rat
intracellular signal transductionGO:00355563140.034
regulation of multicellular organismal developmentGO:20000263760.033
regulation of intracellular signal transductionGO:19025312180.033
neuron developmentGO:00486662860.033
cellular amine metabolic processGO:0044106380.033
muscle contractionGO:0006936880.033
cellular ketone metabolic processGO:0042180510.032
transmembrane transportGO:00550854120.032
Rat
response to peptideGO:19016522920.031
carbohydrate derivative metabolic processGO:19011353460.031
protein complex assemblyGO:00064612630.031
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
positive regulation of phosphorus metabolic processGO:00105622620.030
protein complex biogenesisGO:00702712630.030
response to hypoxiaGO:00016662310.030
regulation of cell proliferationGO:00421273590.030
organic substance catabolic processGO:19015753160.030
macromolecular complex assemblyGO:00650032730.030
positive regulation of molecular functionGO:00440932300.030
lipid metabolic processGO:00066292830.030
regulation of cellular ketone metabolic processGO:0010565270.029
regulation of programmed cell deathGO:00430673410.029
secretion by cellGO:00329402480.029
cellular component movementGO:00069282480.029
response to inorganic substanceGO:00100353770.029
regulation of apoptotic processGO:00429813350.029
organelle organizationGO:00069962660.029
cardiac conductionGO:006133720.028
metal ion transportGO:00300012890.028
Rat
regulation of cellular localizationGO:00603412630.028
regulation of cell projection organizationGO:00313441750.028
protein complex subunit organizationGO:00718223020.028
regulation of system processGO:00440572080.027
neuron projection developmentGO:00311752730.027
regulation of neurogenesisGO:00507672470.027
transcription dna templatedGO:00063513770.026
action potentialGO:0001508540.026
response to decreased oxygen levelsGO:00362932370.026
regulation of neuron differentiationGO:00456642080.026
muscle system processGO:00030121150.026
regulation of cell differentiationGO:00455953200.026
regulation of secretion by cellGO:19035302080.026
single organism catabolic processGO:00447122830.026
regulation of phosphorylationGO:00423252480.026
response to nutrient levelsGO:00316673700.025
positive regulation of catalytic activityGO:00430851840.025
regulation of signal transductionGO:00099663180.025
cellular response to hormone stimulusGO:00328702470.025
rna metabolic processGO:00160704060.025
neurological system processGO:00508772190.025
cellular component morphogenesisGO:00329891550.025
protein oligomerizationGO:00512591910.025
organophosphate metabolic processGO:00196373700.024
regulation of nervous system developmentGO:00519602640.024
negative regulation of cellular metabolic processGO:00313242810.024
cardiac muscle contractionGO:0060048270.024
cell morphogenesis involved in differentiationGO:00009041190.024
cellular response to oxygen containing compoundGO:19017013860.024
amine metabolic processGO:0009308380.024
neuronal action potentialGO:0019228350.024
positive regulation of cellular biosynthetic processGO:00313282950.024
rna biosynthetic processGO:00327743800.024
regulation of cellular component organizationGO:00511283680.024
peptidyl amino acid modificationGO:00181931260.023
negative regulation of metabolic processGO:00098923310.023
apoptotic processGO:00069153810.023
regulation of rna biosynthetic processGO:20011413810.023
multicellular organismal signalingGO:0035637440.023
positive regulation of cell communicationGO:00106472710.023
regulation of rna metabolic processGO:00512523910.023
positive regulation of developmental processGO:00510942830.023
cell morphogenesisGO:00009021420.022
gland developmentGO:00487321550.022
positive regulation of cell proliferationGO:00082842490.022
synaptic transmissionGO:00072682350.022
striated muscle contractionGO:0006941440.022
protein localizationGO:00081041910.022
response to peptide hormoneGO:00434342780.022
cell cell signalingGO:00072673350.022
programmed cell deathGO:00125013920.021
negative regulation of multicellular organismal processGO:00512412030.021
tissue developmentGO:00098882520.021
head developmentGO:00603222470.021
brain developmentGO:00074202470.021
regulation of protein modification processGO:00313991940.021
nucleoside phosphate metabolic processGO:00067532830.021
cellular response to peptideGO:19016531330.021
ion transmembrane transportGO:00342203650.021
Rat
positive regulation of phosphate metabolic processGO:00459372620.021
regulation of protein phosphorylationGO:00019321830.021
cellular response to nitrogen compoundGO:19016992100.021
regulation of cell developmentGO:00602842630.021
cation transmembrane transportGO:00986552630.020
Rat
lipid biosynthetic processGO:00086101280.020
oxidation reduction processGO:00551143040.020
cardiac muscle cell contractionGO:0086003100.020
regulation of protein metabolic processGO:00512462890.020
ras protein signal transductionGO:0007265290.020
regulation of cellular protein metabolic processGO:00322682670.020
anion transportGO:00068201780.020
Rat
positive regulation of signalingGO:00230562700.020
response to oxygen levelsGO:00704822650.020
negative regulation of response to stimulusGO:00485851550.019
neuron projection morphogenesisGO:00488121220.019
regulation of secretionGO:00510462240.019
cell migrationGO:00164771970.019
nucleoside metabolic processGO:00091161790.019
positive regulation of transportGO:00510502450.019
cellular homeostasisGO:00197252520.019
vesicle mediated transportGO:00161921810.019
cell morphogenesis involved in neuron differentiationGO:00486671060.019
organic hydroxy compound metabolic processGO:19016151150.019
negative regulation of nervous system developmentGO:0051961790.018
catabolic processGO:00090563510.018
positive regulation of neurogenesisGO:00507691650.018
cellular response to organic cyclic compoundGO:00714072020.018
localization of cellGO:00516742020.018
transmission of nerve impulseGO:0019226420.018
cardiac muscle cell action potential involved in contractionGO:008600220.018
cell motilityGO:00488702020.018
central nervous system developmentGO:00074173110.018
small gtpase mediated signal transductionGO:0007264360.018
reproductive processGO:00224143720.018
inorganic ion transmembrane transportGO:00986602290.018
Rat
signal releaseGO:00230611450.018
response to metal ionGO:00100382530.018
axis specificationGO:000979840.018
response to extracellular stimulusGO:00099913800.018
cell part morphogenesisGO:00329901230.017
response to insulinGO:00328681330.017
organophosphate biosynthetic processGO:00904071430.017
actin mediated cell contractionGO:0070252120.017
immune system processGO:00023762040.017
regulation of catabolic processGO:00098941130.017
cellular chemical homeostasisGO:00550822470.017
Rat
multicellular organism growthGO:003526410.017
cellular cation homeostasisGO:00300031800.016
Rat
hepaticobiliary system developmentGO:0061008900.016
mesoderm developmentGO:000749820.016
nucleobase containing small molecule metabolic processGO:00550863160.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
locomotionGO:00400112370.016
positive regulation of cellular amine metabolic processGO:003324030.016
regulation of mapk cascadeGO:00434081160.016
cellular metal ion homeostasisGO:00068751720.016
positive regulation of phosphorylationGO:00423271770.016
cation homeostasisGO:00550801950.016
Rat
cardiac ventricle developmentGO:000323110.016
nucleotide metabolic processGO:00091172790.016
oligopeptide transportGO:000685740.016
reproductionGO:00000032450.016
carbohydrate derivative biosynthetic processGO:19011371240.016
dephosphorylationGO:0016311980.016
regulation of neuron projection developmentGO:00109751610.015
positive regulation of response to stimulusGO:00485842850.015
gliogenesisGO:0042063930.015
behaviorGO:00076102050.015
cellular response to external stimulusGO:00714961180.015
regulation of tube sizeGO:0035150890.015
negative regulation of cell proliferationGO:00082851190.015
regulation of cellular catabolic processGO:00313291010.015
positive regulation of cellular component organizationGO:00511302000.015
motor neuron axon guidanceGO:000804510.015
positive regulation of gene expressionGO:00106282440.015
positive regulation of cell differentiationGO:00455972170.015
regulation of purine nucleotide metabolic processGO:19005421150.015
inorganic cation transmembrane transportGO:00986622020.015
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.015
response to growth factorGO:00708481890.015
heart morphogenesisGO:000300730.015
response to transition metal nanoparticleGO:19902671220.015
organic acid transportGO:00158491160.015
positive regulation of biosynthetic processGO:00098913190.015
regulation of muscle system processGO:0090257790.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
synaptic growth at neuromuscular junctionGO:005112410.015
intracellular transportGO:00469071850.015
regulation of muscle contractionGO:0006937530.015
positive regulation of protein phosphorylationGO:00019341350.014
cellular response to peptide hormone stimulusGO:00713751200.014
cellular response to growth factor stimulusGO:00713631620.014
regulation of neuron apoptotic processGO:0043523830.014
positive regulation of cell developmentGO:00107201760.014
chemical homeostasisGO:00488782920.014
Rat
purine containing compound metabolic processGO:00725212530.014
response to estrogenGO:00436272320.014
regulation of blood circulationGO:19035221100.014
gastrulationGO:000736920.014
nucleic acid templated transcriptionGO:00976593790.014
regenerationGO:00310991630.014
multicellular organismal reproductive processGO:00486092330.014
negative regulation of neurogenesisGO:0050768780.014
establishment of protein localizationGO:00451841410.014
cellular response to organonitrogen compoundGO:00714171970.014
organic anion transportGO:00157111320.014
growthGO:00400071650.014
protein autophosphorylationGO:0046777660.014
transcription from rna polymerase ii promoterGO:00063662520.014
response to ethanolGO:00454711620.014
cell cell junction organizationGO:0045216200.013
positive regulation of cellular protein metabolic processGO:00322701670.013
rhythmic processGO:00485111560.013
regulation of cellular component movementGO:00512701500.013
regulation of hormone levelsGO:00108171870.013
regulation of protein kinase activityGO:00458591050.013
single organism intracellular transportGO:19025821660.013
regulation of kinase activityGO:00435491170.013
regulation of ion transportGO:00432692450.013
ribonucleoside metabolic processGO:00091191740.013
liver developmentGO:0001889900.013
ribose phosphate metabolic processGO:00196932350.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
regulation of vesicle mediated transportGO:0060627810.013
metal ion homeostasisGO:00550651860.013
anion transmembrane transportGO:0098656770.013
Rat
heart contractionGO:0060047570.013
cellular response to tumor necrosis factorGO:0071356460.013
regulation of hormone secretionGO:00468831060.013
regulation of striated muscle contractionGO:0006942210.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
single organism reproductive processGO:00447022970.013
neurotransmitter transportGO:0006836420.013
chromosome segregationGO:000705920.013
regulation of nucleotide metabolic processGO:00061401170.013
carboxylic acid transportGO:00469421150.013
tube developmentGO:0035295890.013
regulation of blood vessel sizeGO:0050880890.013
protein heterooligomerizationGO:0051291890.013
negative regulation of transportGO:00510511360.013
response to cytokineGO:00340972150.012
positive regulation of kinase activityGO:0033674770.012
mechanoreceptor differentiationGO:004249020.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
divalent inorganic cation homeostasisGO:00725071650.012
regulation of canonical wnt signaling pathwayGO:006082840.012
negative regulation of developmental processGO:00510931250.012
cellular calcium ion homeostasisGO:00068741600.012
cellular lipid metabolic processGO:00442552080.012
positive regulation of secretion by cellGO:19035321280.012
epithelium developmentGO:0060429960.012
dna metabolic processGO:0006259960.012
membrane organizationGO:0061024940.012
cellular ion homeostasisGO:00068731840.012
Rat
positive regulation of programmed cell deathGO:00430681570.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of protein serine threonine kinase activityGO:0071902520.012
negative regulation of cell developmentGO:0010721820.012
positive regulation of cell projection organizationGO:00313461110.012
negative regulation of neuron differentiationGO:0045665620.012
positive regulation of nervous system developmentGO:00519621780.012
heart processGO:0003015570.012
multicellular organism reproductionGO:00325042330.012
negative regulation of phosphorus metabolic processGO:0010563800.012
single organism carbohydrate metabolic processGO:00447231180.012
cell projection morphogenesisGO:00488581230.012
negative regulation of macromolecule metabolic processGO:00106052600.012
negative regulation of cell communicationGO:00106481580.012
protein transportGO:00150311320.012
positive regulation of rna biosynthetic processGO:19026801970.012
vascular process in circulatory systemGO:0003018960.012
development of primary sexual characteristicsGO:00451371070.012
organic cyclic compound catabolic processGO:19013611750.012
positive regulation of rna metabolic processGO:00512542030.012
regulation of blood pressureGO:0008217830.012
positive regulation of protein kinase activityGO:0045860730.012
embryonic pattern specificationGO:000988010.011
sex differentiationGO:00075481130.011
heterocycle catabolic processGO:00467001670.011
cell differentiation involved in kidney developmentGO:006100540.011
monovalent inorganic cation transportGO:00156721720.011
Rat
cellular divalent inorganic cation homeostasisGO:00725031620.011
negative regulation of programmed cell deathGO:00430691830.011
regulation of proteasomal protein catabolic processGO:006113640.011
single organism behaviorGO:00447081300.011
neuron deathGO:00709971270.011
regulation of response to stressGO:00801341260.011
ribonucleotide metabolic processGO:00092592310.011
divalent metal ion transportGO:00708381320.011
organonitrogen compound catabolic processGO:19015651790.011
choline transportGO:001587140.011
developmental growthGO:00485891000.011
positive regulation of protein metabolic processGO:00512471780.011
adult locomotory behaviorGO:000834440.011
glycosyl compound metabolic processGO:19016571820.011
response to woundingGO:00096112540.011
glycerolipid metabolic processGO:0046486670.011
regulation of transferase activityGO:00513381230.011
appendage morphogenesisGO:003510740.011
regulation of cardiac muscle contractionGO:0055117170.011
purine nucleotide metabolic processGO:00061632290.011
nucleobase containing compound catabolic processGO:00346551520.011
regulation of locomotionGO:00400121480.011
g protein coupled receptor signaling pathwayGO:00071862420.011
eye morphogenesisGO:004859240.011
alcohol metabolic processGO:0006066770.011
protein homooligomerizationGO:0051260910.011
gonad developmentGO:00084061040.011
purine ribonucleoside metabolic processGO:00461281680.011
purine nucleoside metabolic processGO:00422781690.011
carbohydrate derivative catabolic processGO:19011361470.011
axon developmentGO:0061564960.011
single organism organelle organizationGO:19025891800.011
regulation of synaptic transmissionGO:00508041410.011
purine ribonucleotide metabolic processGO:00091502270.011
regulation of protein serine threonine kinase activityGO:0071900640.011
peptide transportGO:0015833970.010
negative regulation of biosynthetic processGO:00098901680.010
auditory receptor cell differentiationGO:004249120.010
negative regulation of cellular component organizationGO:0051129830.010
regulation of neurotransmitter levelsGO:0001505420.010
carbohydrate metabolic processGO:00059751300.010
anterior posterior pattern specificationGO:000995210.010
regulation of hydrolase activityGO:00513361430.010
cellular response to cytokine stimulusGO:00713451270.010
proteolysisGO:00065081750.010
cellular response to stressGO:00335542690.010
organophosphate catabolic processGO:00464341480.010
regulation of neuron deathGO:19012141150.010
negative regulation of cell deathGO:00605482290.010
nucleoside triphosphate metabolic processGO:00091411440.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
positive regulation of transcription dna templatedGO:00458931970.010
ovulation cycleGO:0042698670.010
hormone transportGO:00099141210.010
alpha amino acid metabolic processGO:1901605710.010

Slc12a7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.053
disease of anatomical entityDOID:700.053
myopathyDOID:42300.045
muscular diseaseDOID:008000000.045
muscle tissue diseaseDOID:6600.045
musculoskeletal system diseaseDOID:1700.045
heart diseaseDOID:11400.028
intrinsic cardiomyopathyDOID:006003600.020
cardiomyopathyDOID:005070000.020
nervous system diseaseDOID:86300.016
arrhythmogenic right ventricular cardiomyopathyDOID:005043100.015
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
disease of cellular proliferationDOID:1456600.010