Rattus norvegicus

49 known processes

Slc12a2

solute carrier family 12 (sodium/potassium/chloride transporters), member 2

(Aliases: Bsc2,Nkcc1)

Slc12a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203650.214
transmembrane transportGO:00550854120.158
positive regulation of multicellular organismal processGO:00512403870.136
neuron differentiationGO:00301823680.124
carboxylic acid metabolic processGO:00197522890.122
neuron developmentGO:00486662860.109
regulation of cell projection organizationGO:00313441750.103
cellular component movementGO:00069282480.099
localization of cellGO:00516742020.098
cation transportGO:00068123820.098
oxoacid metabolic processGO:00434362900.098
organic acid metabolic processGO:00060822920.093
cellular response to stressGO:00335542690.088
regulation of multicellular organismal developmentGO:20000263760.088
cell cell signalingGO:00072673350.086
intracellular signal transductionGO:00355563140.084
cell migrationGO:00164771970.083
regulation of neuron projection developmentGO:00109751610.080
nitrogen compound transportGO:00717052290.079
positive regulation of cellular component organizationGO:00511302000.078
regulation of cellular component organizationGO:00511283680.078
regulation of neuron differentiationGO:00456642080.078
regulation of signal transductionGO:00099663180.076
neuron projection developmentGO:00311752730.074
metal ion transportGO:00300012890.074
response to extracellular stimulusGO:00099913800.073
response to nutrient levelsGO:00316673700.073
cell projection organizationGO:00300303020.072
regulation of neurogenesisGO:00507672470.071
regulation of nucleic acid templated transcriptionGO:19035063800.070
regulation of nervous system developmentGO:00519602640.069
cellular response to oxygen containing compoundGO:19017013860.069
regulation of cell differentiationGO:00455953200.069
cellular response to endogenous stimulusGO:00714953770.067
regulation of cell developmentGO:00602842630.066
positive regulation of developmental processGO:00510942830.066
cation transmembrane transportGO:00986552630.062
cellular response to organic cyclic compoundGO:00714072020.061
response to metal ionGO:00100382530.060
regulation of cellular component movementGO:00512701500.060
positive regulation of biosynthetic processGO:00098913190.060
nucleic acid templated transcriptionGO:00976593790.060
regulation of transcription dna templatedGO:00063553740.059
negative regulation of signalingGO:00230571570.059
response to inorganic substanceGO:00100353770.059
single organism biosynthetic processGO:00447113420.059
negative regulation of response to stimulusGO:00485851550.057
cell motilityGO:00488702020.057
organophosphate metabolic processGO:00196373700.057
catabolic processGO:00090563510.056
lipid metabolic processGO:00066292830.055
Rat
inorganic ion transmembrane transportGO:00986602290.055
positive regulation of neurogenesisGO:00507691650.053
locomotionGO:00400112370.052
response to acid chemicalGO:00011012220.052
positive regulation of nitrogen compound metabolic processGO:00511733340.052
regulation of rna biosynthetic processGO:20011413810.051
defense responseGO:00069521940.051
regulation of transcription from rna polymerase ii promoterGO:00063572340.051
negative regulation of multicellular organismal processGO:00512412030.051
rna biosynthetic processGO:00327743800.050
inorganic cation transmembrane transportGO:00986622020.050
Rat
central nervous system developmentGO:00074173110.049
transcription from rna polymerase ii promoterGO:00063662520.048
rna metabolic processGO:00160704060.048
negative regulation of metabolic processGO:00098923310.048
regulation of intracellular signal transductionGO:19025312180.048
cellular lipid metabolic processGO:00442552080.047
Rat
cellular component assemblyGO:00226073600.047
cellular catabolic processGO:00442482950.047
positive regulation of cellular biosynthetic processGO:00313282950.046
transcription dna templatedGO:00063513770.045
regulation of molecular functionGO:00650093980.044
protein phosphorylationGO:00064683450.043
positive regulation of cell differentiationGO:00455972170.043
positive regulation of nervous system developmentGO:00519621780.043
positive regulation of cell developmentGO:00107201760.043
regulation of catalytic activityGO:00507903040.042
response to peptideGO:19016522920.042
positive regulation of transportGO:00510502450.042
negative regulation of signal transductionGO:0009968830.042
negative regulation of cell communicationGO:00106481580.042
nucleobase containing small molecule metabolic processGO:00550863160.042
regulation of ion transportGO:00432692450.042
neurological system processGO:00508772190.041
positive regulation of neuron projection developmentGO:0010976990.041
regulation of membrane potentialGO:00423911100.041
regulation of phosphate metabolic processGO:00192203490.041
programmed cell deathGO:00125013920.041
response to woundingGO:00096112540.040
positive regulation of gene expressionGO:00106282440.040
negative regulation of transportGO:00510511360.040
regulation of rna metabolic processGO:00512523910.040
homeostatic processGO:00425923310.040
gland developmentGO:00487321550.040
positive regulation of response to stimulusGO:00485842850.040
positive regulation of cell projection organizationGO:00313461110.039
cellular response to hormone stimulusGO:00328702470.039
chemical homeostasisGO:00488782920.039
cellular amino acid metabolic processGO:00065201070.039
anion transportGO:00068201780.038
response to other organismGO:00517072200.038
response to hypoxiaGO:00016662310.038
intracellular transportGO:00469071850.038
positive regulation of signalingGO:00230562700.037
cellular response to organonitrogen compoundGO:00714171970.037
positive regulation of cell communicationGO:00106472710.037
response to oxygen levelsGO:00704822650.037
cellular component biogenesisGO:00440853680.036
response to glucocorticoidGO:00513842230.036
single organism catabolic processGO:00447122830.036
regulation of protein metabolic processGO:00512462890.036
regulation of cell proliferationGO:00421273590.036
carboxylic acid transportGO:00469421150.035
positive regulation of phosphate metabolic processGO:00459372620.035
positive regulation of catalytic activityGO:00430851840.035
synaptic transmissionGO:00072682350.035
positive regulation of neuron differentiationGO:00456661260.035
agingGO:00075682410.034
positive regulation of phosphorus metabolic processGO:00105622620.034
single organism intracellular transportGO:19025821660.034
carbohydrate derivative metabolic processGO:19011353460.034
cellular ketone metabolic processGO:0042180510.034
cellular chemical homeostasisGO:00550822470.034
regulation of response to external stimulusGO:00321011060.033
circulatory system developmentGO:00723591340.033
regulation of protein modification processGO:00313991940.033
cellular homeostasisGO:00197252520.033
tissue developmentGO:00098882520.033
amine metabolic processGO:0009308380.033
regulation of phosphorylationGO:00423252480.033
response to growth factorGO:00708481890.033
response to decreased oxygen levelsGO:00362932370.033
positive regulation of macromolecule biosynthetic processGO:00105572470.032
organic substance catabolic processGO:19015753160.032
regulation of cellular protein metabolic processGO:00322682670.031
cellular ion homeostasisGO:00068731840.031
macromolecule localizationGO:00330362520.031
Rat
neuronal action potentialGO:0019228350.031
regulation of cell migrationGO:00303341280.031
positive regulation of rna metabolic processGO:00512542030.030
cellular amine metabolic processGO:0044106380.030
regulation of locomotionGO:00400121480.030
macromolecular complex assemblyGO:00650032730.030
response to peptide hormoneGO:00434342780.030
neuron projection morphogenesisGO:00488121220.030
response to monosaccharideGO:00342841590.030
regenerationGO:00310991630.030
regulation of cellular amino acid metabolic processGO:000652120.030
potassium ion transportGO:0006813970.030
cardiovascular system developmentGO:00723581340.029
cellular response to nitrogen compoundGO:19016992100.029
regulation of phosphorus metabolic processGO:00511743490.029
action potentialGO:0001508540.029
regulation of synaptic transmissionGO:00508041410.029
ras protein signal transductionGO:0007265290.029
positive regulation of rna biosynthetic processGO:19026801970.028
negative regulation of cellular metabolic processGO:00313242810.028
small gtpase mediated signal transductionGO:0007264360.028
secretionGO:00469033070.028
positive regulation of protein modification processGO:00314011420.028
organophosphate catabolic processGO:00464341480.028
ion homeostasisGO:00508012120.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
macromolecular complex subunit organizationGO:00439333390.027
nucleoside phosphate metabolic processGO:00067532830.027
g protein coupled receptor signaling pathwayGO:00071862420.027
response to corticosteroidGO:00319602350.027
regulation of response to stressGO:00801341260.027
protein localizationGO:00081041910.027
Rat
brain developmentGO:00074202470.026
positive regulation of locomotionGO:00400171020.026
regulation of system processGO:00440572080.026
positive regulation of cell deathGO:00109421840.026
positive regulation of cell proliferationGO:00082842490.026
response to external biotic stimulusGO:00432072210.026
reproductionGO:00000032450.026
positive regulation of molecular functionGO:00440932300.026
positive regulation of signal transductionGO:00099671750.026
regulation of hydrolase activityGO:00513361430.026
immune system processGO:00023762040.026
carbohydrate metabolic processGO:00059751300.026
head developmentGO:00603222470.026
secretion by cellGO:00329402480.026
regulation of apoptotic processGO:00429813350.025
negative regulation of cell proliferationGO:00082851190.025
regulation of cellular amine metabolic processGO:003323880.025
cellular component morphogenesisGO:00329891550.025
cellular response to cytokine stimulusGO:00713451270.025
monovalent inorganic cation transportGO:00156721720.025
cellular cation homeostasisGO:00300031800.025
cellular response to growth factor stimulusGO:00713631620.025
dephosphorylationGO:0016311980.025
negative regulation of macromolecule metabolic processGO:00106052600.025
response to biotic stimulusGO:00096072260.025
regulation of secretion by cellGO:19035302080.025
vesicle mediated transportGO:00161921810.025
taxisGO:0042330670.025
nucleotide metabolic processGO:00091172790.025
negative regulation of cell deathGO:00605482290.024
regulation of cell motilityGO:20001451310.024
multicellular organismal reproductive processGO:00486092330.024
enzyme linked receptor protein signaling pathwayGO:00071671160.024
divalent metal ion transportGO:00708381320.024
protein complex subunit organizationGO:00718223020.024
cell projection morphogenesisGO:00488581230.024
biological adhesionGO:00226101100.024
response to glucoseGO:00097491360.024
response to cytokineGO:00340972150.024
cation homeostasisGO:00550801950.023
negative regulation of developmental processGO:00510931250.023
protein transportGO:00150311320.023
single organism reproductive processGO:00447022970.023
reproductive processGO:00224143720.023
positive regulation of protein phosphorylationGO:00019341350.023
regulation of protein phosphorylationGO:00019321830.023
cell morphogenesisGO:00009021420.023
response to hexoseGO:00097461440.023
organic cyclic compound catabolic processGO:19013611750.023
growthGO:00400071650.023
regulation of catabolic processGO:00098941130.023
cellular response to insulin stimulusGO:0032869810.023
heart morphogenesisGO:000300730.023
cellular metal ion homeostasisGO:00068751720.022
regulation of cellular localizationGO:00603412630.022
response to estradiolGO:00323551640.022
divalent inorganic cation homeostasisGO:00725071650.022
axon ensheathmentGO:0008366400.022
regulation of cellular ketone metabolic processGO:0010565270.022
positive regulation of cellular component movementGO:00512721020.022
regulation of secretionGO:00510462240.022
response to estrogenGO:00436272320.022
circulatory system processGO:00030131830.022
cellular macromolecule localizationGO:00707271220.022
Rat
mapk cascadeGO:00001651400.022
calcium ion transportGO:00068161310.022
positive regulation of protein metabolic processGO:00512471780.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
regulation of transmembrane transportGO:00347621220.022
muscle system processGO:00030121150.022
response to purine containing compoundGO:00140741260.022
ensheathment of neuronsGO:0007272400.021
regulation of hormone levelsGO:00108171870.021
cellular response to peptideGO:19016531330.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
behaviorGO:00076102050.021
regulation of ion transmembrane transportGO:00347651210.021
positive regulation of transcription dna templatedGO:00458931970.021
multicellular organism reproductionGO:00325042330.021
multi organism reproductive processGO:00447032620.021
transmission of nerve impulseGO:0019226420.021
metal ion homeostasisGO:00550651860.021
organic acid transportGO:00158491160.021
multicellular organismal signalingGO:0035637440.020
apoptotic processGO:00069153810.020
response to nutrientGO:00075842480.020
learning or memoryGO:0007611900.020
blood circulationGO:00080151830.020
cardiac chamber developmentGO:000320510.020
ribonucleotide metabolic processGO:00092592310.020
rhythmic processGO:00485111560.020
response to carbohydrateGO:00097431830.020
regulation of programmed cell deathGO:00430673410.020
cellular calcium ion homeostasisGO:00068741600.020
positive regulation of cellular protein metabolic processGO:00322701670.020
aromatic compound catabolic processGO:00194391680.020
protein oligomerizationGO:00512591910.020
hormone transportGO:00099141210.020
cellular response to peptide hormone stimulusGO:00713751200.019
purine nucleoside metabolic processGO:00422781690.019
establishment of protein localizationGO:00451841410.019
Rat
positive regulation of phosphorylationGO:00423271770.019
cell morphogenesis involved in differentiationGO:00009041190.019
axon developmentGO:0061564960.019
regulation of cellular catabolic processGO:00313291010.019
inflammatory responseGO:00069541500.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
organelle organizationGO:00069962660.019
cell adhesionGO:00071551100.019
positive regulation of cellular amine metabolic processGO:003324030.019
regulation of anatomical structure morphogenesisGO:00226031410.019
organonitrogen compound catabolic processGO:19015651790.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
negative regulation of programmed cell deathGO:00430691830.018
divalent inorganic cation transportGO:00725111340.018
negative regulation of neurogenesisGO:0050768780.018
chemotaxisGO:0006935660.018
regulation of hormone secretionGO:00468831060.018
anatomical structure morphogenesisGO:00096532980.018
purine containing compound catabolic processGO:00725231380.018
protein complex assemblyGO:00064612630.018
response to alkaloidGO:00432791320.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
cellular response to alcoholGO:0097306870.018
protein complex biogenesisGO:00702712630.018
cellular protein localizationGO:00346131220.018
Rat
single organism carbohydrate metabolic processGO:00447231180.018
endocytosisGO:0006897840.018
amide transportGO:00428861050.018
ribose phosphate metabolic processGO:00196932350.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
single organism organelle organizationGO:19025891800.017
proteolysisGO:00065081750.017
cellular response to corticosteroid stimulusGO:0071384690.017
negative regulation of molecular functionGO:00440921330.017
anterior posterior pattern specificationGO:000995210.017
single organism cellular localizationGO:19025801020.017
Rat
actin filament based processGO:0030029860.017
nucleotide catabolic processGO:00091661390.017
organic hydroxy compound metabolic processGO:19016151150.017
response to ketoneGO:19016541820.017
regulation of anatomical structure sizeGO:00900661350.017
regulation of transferase activityGO:00513381230.017
regulation of growthGO:00400081050.017
regulation of response to woundingGO:1903034690.017
regulation of blood circulationGO:19035221100.017
glycosyl compound catabolic processGO:19016581260.017
epithelium developmentGO:0060429960.017
calcium ion homeostasisGO:00550741620.017
cell type specific apoptotic processGO:00972851340.017
response to bacteriumGO:00096172000.017
glycosyl compound metabolic processGO:19016571820.016
purine ribonucleoside metabolic processGO:00461281680.016
cell growthGO:00160491040.016
regulation of cell growthGO:0001558850.016
heterocycle catabolic processGO:00467001670.016
response to lipopolysaccharideGO:00324961910.016
negative regulation of response to external stimulusGO:0032102370.016
peptidyl amino acid modificationGO:00181931260.016
purine ribonucleotide metabolic processGO:00091502270.016
ribonucleoside metabolic processGO:00091191740.016
carbohydrate derivative catabolic processGO:19011361470.016
cell part morphogenesisGO:00329901230.016
signal transduction by phosphorylationGO:00230141440.016
cellular response to external stimulusGO:00714961180.016
axis specificationGO:000979840.016
purine containing compound metabolic processGO:00725212530.016
glycerolipid metabolic processGO:0046486670.016
organophosphate biosynthetic processGO:00904071430.016
positive regulation of cell migrationGO:0030335960.015
regulation of canonical wnt signaling pathwayGO:006082840.015
synaptic growth at neuromuscular junctionGO:005112410.015
signal releaseGO:00230611450.015
small molecule biosynthetic processGO:00442831240.015
nucleoside triphosphate catabolic processGO:00091431230.015
organonitrogen compound biosynthetic processGO:19015661670.015
eye morphogenesisGO:004859240.015
gliogenesisGO:0042063930.015
positive regulation of secretion by cellGO:19035321280.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
nucleoside phosphate catabolic processGO:19012921400.015
negative regulation of secretionGO:0051048820.015
cellular response to lipidGO:00713962010.015
organic hydroxy compound transportGO:0015850770.015
cytosolic calcium ion homeostasisGO:00514801400.015
regulation of kinase activityGO:00435491170.015
positive regulation of programmed cell deathGO:00430681570.015
nucleoside metabolic processGO:00091161790.015
cardiac muscle cell contractionGO:0086003100.015
alpha amino acid metabolic processGO:1901605710.015
mesoderm developmentGO:000749820.014
intracellular protein transportGO:0006886790.014
cytoplasmic transportGO:00164821150.014
purine ribonucleotide catabolic processGO:00091541360.014
gastrulationGO:000736920.014
negative regulation of gene expressionGO:00106291990.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
regulation of peptide transportGO:0090087870.014
synapse organizationGO:0050808460.014
positive regulation of cell motilityGO:2000147970.014
heart developmentGO:0007507720.014
regulation of neuron deathGO:19012141150.014
response to vitaminGO:00332731310.014
nucleobase containing compound catabolic processGO:00346551520.014
female pregnancyGO:00075651220.014
neural crest cell developmentGO:001403220.014
ribonucleoside catabolic processGO:00424541260.014
developmental process involved in reproductionGO:00030061590.014
chromosome segregationGO:000705920.014
multi multicellular organism processGO:00447061380.014
purine ribonucleoside catabolic processGO:00461301240.014
regulation of metal ion transportGO:00109591180.014
peptide hormone secretionGO:0030072840.014
regulation of proteasomal protein catabolic processGO:006113640.014
ribonucleotide catabolic processGO:00092611360.014
dendrite developmentGO:0016358720.014
positive regulation of secretionGO:00510471400.014
purine nucleotide metabolic processGO:00061632290.014
reproductive system developmentGO:00614581280.013
monocarboxylic acid metabolic processGO:00327871520.013
positive regulation of catabolic processGO:0009896780.013
organ regenerationGO:00311001010.013
positive regulation of ion transportGO:0043270940.013
protein heterooligomerizationGO:0051291890.013
myelinationGO:0042552390.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
amino acid transportGO:0006865700.013
protein homooligomerizationGO:0051260910.013
circadian rhythmGO:0007623880.013
multicellular organism growthGO:003526410.013
negative regulation of nervous system developmentGO:0051961790.013
negative regulation of apoptotic processGO:00430661810.013
small molecule catabolic processGO:0044282590.013
response to organophosphorusGO:00466831020.013
adult locomotory behaviorGO:000834440.013
anion transmembrane transportGO:0098656770.013
dna metabolic processGO:0006259960.013
regulation of synaptic plasticityGO:0048167700.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
response to molecule of bacterial originGO:00022371940.012
carboxylic acid biosynthetic processGO:0046394830.012
regulation of peptide hormone secretionGO:0090276800.012
purine nucleotide catabolic processGO:00061951360.012
single organism behaviorGO:00447081300.012
regulation of body fluid levelsGO:0050878900.012
response to insulinGO:00328681330.012
cellular nitrogen compound catabolic processGO:00442701630.012
phospholipid metabolic processGO:0006644610.012
cellular response to glucocorticoid stimulusGO:0071385680.012
blood vessel morphogenesisGO:0048514580.012
regulation of dendrite developmentGO:0050773590.012
immune responseGO:00069551040.012
carbohydrate derivative biosynthetic processGO:19011371240.012
regulation of insulin secretionGO:0050796650.012
cellular response to steroid hormone stimulusGO:0071383930.012
negative regulation of cellular component organizationGO:0051129830.012
vasculogenesisGO:000157030.012
fatty acid metabolic processGO:0006631990.012
embryonic pattern specificationGO:000988010.012
regulation of peptide secretionGO:0002791820.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
regulation of transporter activityGO:0032409500.012
regulation of muscle system processGO:0090257790.012
protein autophosphorylationGO:0046777660.012
neuron deathGO:00709971270.011
tube formationGO:003514830.011
response to ethanolGO:00454711620.011
negative regulation of secretion by cellGO:1903531720.011
nucleoside catabolic processGO:00091641260.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
peptide secretionGO:0002790860.011
purine nucleoside catabolic processGO:00061521240.011
peptide transportGO:0015833970.011
negative regulation of ion transportGO:0043271510.011
maintenance of locationGO:0051235170.011
negative regulation of biosynthetic processGO:00098901680.011
regulation of protein kinase activityGO:00458591050.011
carbohydrate homeostasisGO:0033500750.011
metaphase anaphase transition of cell cycleGO:004478410.011
epithelial cell differentiationGO:0030855710.011
oxidation reduction processGO:00551143040.011
sensory organ developmentGO:0007423740.011
regulation of stem cell differentiationGO:200073620.011
regulation of sister chromatid segregationGO:003304510.011
positive regulation of apoptotic processGO:00430651540.011
developmental growthGO:00485891000.011
blood vessel developmentGO:0001568690.011
camera type eye morphogenesisGO:004859320.011
nucleoside triphosphate metabolic processGO:00091411440.011
regulation of mapk cascadeGO:00434081160.011
morphogenesis of embryonic epitheliumGO:001633130.011
organic acid biosynthetic processGO:0016053830.011
negative regulation of catalytic activityGO:00430861030.011
organic anion transportGO:00157111320.011
cardiac ventricle developmentGO:000323110.011
negative regulation of cell developmentGO:0010721820.010
lipid biosynthetic processGO:00086101280.010
cognitionGO:0050890920.010
neuron apoptotic processGO:0051402880.010
regulation of cellular component biogenesisGO:0044087860.010
sexual reproductionGO:00199531480.010
cellular response to extracellular stimulusGO:0031668730.010
regulation of protein serine threonine kinase activityGO:0071900640.010
response to calcium ionGO:0051592590.010
defense response to gram negative bacteriumGO:005082930.010
regulation of smooth muscle cell proliferationGO:0048660750.010
regulation of intracellular transportGO:0032386650.010
regulation of immune system processGO:00026821230.010
regulation of cell morphogenesisGO:0022604770.010
regulation of calcium ion transportGO:0051924770.010
neural crest cell differentiationGO:001403320.010
response to transition metal nanoparticleGO:19902671220.010
hormone secretionGO:00468791150.010
positive regulation of mapk cascadeGO:0043410920.010
positive regulation of cellular catabolic processGO:0031331710.010

Slc12a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.045
sensory system diseaseDOID:005015500.019
eye diseaseDOID:561400.016
eye and adnexa diseaseDOID:149200.016
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.011
organ system cancerDOID:005068600.011
central nervous system diseaseDOID:33100.011