Rattus norvegicus

0 known processes

Lgmn

legumain

(Aliases: Prsc1,MGC105274)

Lgmn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.149
organic acid metabolic processGO:00060822920.130
growthGO:00400071650.117
programmed cell deathGO:00125013920.114
response to nutrient levelsGO:00316673700.105
carboxylic acid metabolic processGO:00197522890.101
cellular response to endogenous stimulusGO:00714953770.100
response to estradiolGO:00323551640.092
response to glucocorticoidGO:00513842230.088
reproductive processGO:00224143720.079
response to peptide hormoneGO:00434342780.076
regulation of system processGO:00440572080.073
regulation of programmed cell deathGO:00430673410.071
response to estrogenGO:00436272320.070
response to extracellular stimulusGO:00099913800.070
regulation of cellular component organizationGO:00511283680.068
response to peptideGO:19016522920.064
response to corticosteroidGO:00319602350.064
response to biotic stimulusGO:00096072260.061
cellular response to hormone stimulusGO:00328702470.060
cell projection organizationGO:00300303020.060
response to monosaccharideGO:00342841590.058
multicellular organism reproductionGO:00325042330.058
response to woundingGO:00096112540.057
positive regulation of cell proliferationGO:00082842490.056
response to ethanolGO:00454711620.056
cellular amino acid metabolic processGO:00065201070.054
tissue developmentGO:00098882520.054
cation transportGO:00068123820.053
regulation of neuron differentiationGO:00456642080.052
regulation of leukocyte activationGO:0002694450.051
response to external biotic stimulusGO:00432072210.051
cellular response to organic cyclic compoundGO:00714072020.050
amine metabolic processGO:0009308380.050
lymphocyte activationGO:0046649430.050
vesicle mediated transportGO:00161921810.050
multi organism reproductive processGO:00447032620.049
cellular response to oxygen containing compoundGO:19017013860.047
wound healingGO:00420601220.046
organic substance catabolic processGO:19015753160.046
regulation of cellular ketone metabolic processGO:0010565270.046
regulation of vesicle mediated transportGO:0060627810.045
response to carbohydrateGO:00097431830.045
positive regulation of transportGO:00510502450.045
single organism biosynthetic processGO:00447113420.045
organic acid biosynthetic processGO:0016053830.045
regulation of locomotionGO:00400121480.045
cellular response to nitrogen compoundGO:19016992100.045
anatomical structure morphogenesisGO:00096532980.045
response to inorganic substanceGO:00100353770.044
reproductive structure developmentGO:00486081280.044
single organism reproductive processGO:00447022970.044
reproductionGO:00000032450.043
regulation of cell proliferationGO:00421273590.043
regulation of cell differentiationGO:00455953200.043
regulation of cellular component movementGO:00512701500.042
small molecule biosynthetic processGO:00442831240.041
positive regulation of multicellular organismal processGO:00512403870.040
anion transportGO:00068201780.040
regulation of cellular amino acid metabolic processGO:000652120.040
response to oxygen levelsGO:00704822650.040
cell activationGO:0001775970.039
organic acid transportGO:00158491160.039
nucleic acid templated transcriptionGO:00976593790.038
positive regulation of response to stimulusGO:00485842850.037
urogenital system developmentGO:0001655780.037
apoptotic processGO:00069153810.037
response to other organismGO:00517072200.037
regulation of transcription dna templatedGO:00063553740.037
response to hexoseGO:00097461440.037
developmental process involved in reproductionGO:00030061590.037
cellular amine metabolic processGO:0044106380.037
regulation of secretionGO:00510462240.037
organic anion transportGO:00157111320.036
kidney developmentGO:0001822670.036
cellular ketone metabolic processGO:0042180510.036
regulation of cellular localizationGO:00603412630.036
response to acid chemicalGO:00011012220.036
secretionGO:00469033070.036
catabolic processGO:00090563510.036
synaptic transmissionGO:00072682350.035
cellular response to external stimulusGO:00714961180.035
biological adhesionGO:00226101100.035
homeostatic processGO:00425923310.035
single organism catabolic processGO:00447122830.035
regulation of cell motilityGO:20001451310.034
agingGO:00075682410.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
response to bacteriumGO:00096172000.034
nitrogen compound transportGO:00717052290.033
regulation of cell developmentGO:00602842630.033
negative regulation of cell deathGO:00605482290.033
regulation of nervous system developmentGO:00519602640.033
regulation of multicellular organismal developmentGO:20000263760.033
regulation of secretion by cellGO:19035302080.033
multicellular organismal reproductive processGO:00486092330.033
regulation of cellular protein metabolic processGO:00322682670.032
response to glucoseGO:00097491360.032
regulation of apoptotic processGO:00429813350.032
blood circulationGO:00080151830.032
positive regulation of nitrogen compound metabolic processGO:00511733340.031
regulation of ion transportGO:00432692450.031
secretion by cellGO:00329402480.031
cellular response to stressGO:00335542690.031
reproductive system developmentGO:00614581280.031
response to cytokineGO:00340972150.031
metal ion transportGO:00300012890.030
response to molecule of bacterial originGO:00022371940.030
positive regulation of biosynthetic processGO:00098913190.030
carboxylic acid biosynthetic processGO:0046394830.030
positive regulation of macromolecule biosynthetic processGO:00105572470.030
neuron differentiationGO:00301823680.030
cell growthGO:00160491040.030
locomotionGO:00400112370.029
sexual reproductionGO:00199531480.029
positive regulation of cell motilityGO:2000147970.029
developmental growthGO:00485891000.029
regulation of neurogenesisGO:00507672470.029
cellular response to glucocorticoid stimulusGO:0071385680.029
single organism carbohydrate catabolic processGO:0044724400.029
regulation of protein modification processGO:00313991940.029
response to mechanical stimulusGO:00096121340.028
intracellular signal transductionGO:00355563140.028
regulation of rna metabolic processGO:00512523910.028
regulation of cell migrationGO:00303341280.028
cellular lipid metabolic processGO:00442552080.028
positive regulation of cellular component movementGO:00512721020.028
regulation of signal transductionGO:00099663180.028
protein phosphorylationGO:00064683450.027
transcription from rna polymerase ii promoterGO:00063662520.027
transcription dna templatedGO:00063513770.027
cellular chemical homeostasisGO:00550822470.027
response to oxidative stressGO:00069791860.027
negative regulation of cellular biosynthetic processGO:00313271610.027
neuron projection developmentGO:00311752730.027
negative regulation of metabolic processGO:00098923310.027
regulation of hormone levelsGO:00108171870.027
cellular response to mechanical stimulusGO:0071260480.027
immunoglobulin mediated immune responseGO:001606440.026
positive regulation of nervous system developmentGO:00519621780.026
leukocyte activationGO:0045321760.026
cell type specific apoptotic processGO:00972851340.026
monocarboxylic acid metabolic processGO:00327871520.026
cellular catabolic processGO:00442482950.026
regulation of cellular amine metabolic processGO:003323880.026
carbohydrate derivative metabolic processGO:19011353460.026
positive regulation of cell differentiationGO:00455972170.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
b cell mediated immunityGO:001972440.025
epithelium developmentGO:0060429960.025
organic hydroxy compound metabolic processGO:19016151150.025
negative regulation of multicellular organismal processGO:00512412030.025
gamete generationGO:00072761240.024
positive regulation of cell communicationGO:00106472710.024
organophosphate metabolic processGO:00196373700.024
carboxylic acid transportGO:00469421150.024
regulation of protein metabolic processGO:00512462890.024
response to lipopolysaccharideGO:00324961910.024
intracellular transportGO:00469071850.024
response to hypoxiaGO:00016662310.024
regulation of catalytic activityGO:00507903040.024
cellular response to corticosteroid stimulusGO:0071384690.024
rna biosynthetic processGO:00327743800.024
regulation of cell activationGO:0050865500.023
mononuclear cell proliferationGO:0032943290.023
regulation of metal ion transportGO:00109591180.023
single organism carbohydrate metabolic processGO:00447231180.023
female pregnancyGO:00075651220.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
response to nutrientGO:00075842480.023
central nervous system developmentGO:00074173110.023
proteolysisGO:00065081750.023
cell morphogenesisGO:00009021420.023
positive regulation of cellular biosynthetic processGO:00313282950.023
signal releaseGO:00230611450.023
regulation of immunoglobulin productionGO:000263740.023
cell cell signalingGO:00072673350.022
regulation of growthGO:00400081050.022
multicellular organism growthGO:003526410.022
regulation of protein phosphorylationGO:00019321830.022
macromolecule localizationGO:00330362520.022
regulation of immune system processGO:00026821230.022
cellular component morphogenesisGO:00329891550.022
negative regulation of macromolecule metabolic processGO:00106052600.022
positive regulation of signalingGO:00230562700.022
negative regulation of programmed cell deathGO:00430691830.022
cellular response to organonitrogen compoundGO:00714171970.022
negative regulation of cellular metabolic processGO:00313242810.021
negative regulation of apoptotic processGO:00430661810.021
response to growth factorGO:00708481890.021
hormone transportGO:00099141210.021
hematopoietic progenitor cell differentiationGO:000224420.021
regulation of phosphorylationGO:00423252480.021
regulation of cell growthGO:0001558850.021
lipid metabolic processGO:00066292830.021
positive regulation of cellular component organizationGO:00511302000.021
protein oligomerizationGO:00512591910.021
carbohydrate metabolic processGO:00059751300.021
negative regulation of biosynthetic processGO:00098901680.021
transmembrane transportGO:00550854120.021
positive regulation of cellular amine metabolic processGO:003324030.021
lymphocyte proliferationGO:0046651290.020
single organism intracellular transportGO:19025821660.020
muscle cell proliferationGO:0033002840.020
positive regulation of protein modification processGO:00314011420.020
reactive oxygen species metabolic processGO:0072593370.020
regulation of response to stressGO:00801341260.019
regulation of neuron projection developmentGO:00109751610.019
ion transmembrane transportGO:00342203650.019
cell migrationGO:00164771970.019
cellular component biogenesisGO:00440853680.019
regulation of rna biosynthetic processGO:20011413810.019
cellular response to growth factor stimulusGO:00713631620.019
circulatory system processGO:00030131830.019
oxidation reduction processGO:00551143040.019
neuron deathGO:00709971270.019
rna metabolic processGO:00160704060.019
monovalent inorganic cation transportGO:00156721720.019
interleukin 12 productionGO:003261530.019
negative regulation of nucleic acid templated transcriptionGO:19035071170.019
chemical homeostasisGO:00488782920.019
negative regulation of gene expressionGO:00106291990.018
regulation of cell projection organizationGO:00313441750.018
cellular component assemblyGO:00226073600.018
behaviorGO:00076102050.018
multi multicellular organism processGO:00447061380.018
organonitrogen compound biosynthetic processGO:19015661670.018
signal transduction by phosphorylationGO:00230141440.018
positive regulation of developmental processGO:00510942830.018
regulation of blood pressureGO:0008217830.018
response to reactive oxygen speciesGO:00003021200.018
macromolecular complex assemblyGO:00650032730.018
response to organophosphorusGO:00466831020.018
negative regulation of signalingGO:00230571570.018
brain developmentGO:00074202470.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
positive regulation of phosphorylationGO:00423271770.018
positive regulation of molecular functionGO:00440932300.018
localization of cellGO:00516742020.018
cellular response to reactive oxygen speciesGO:0034614550.017
negative regulation of cell communicationGO:00106481580.017
cellular response to peptideGO:19016531330.017
lipid biosynthetic processGO:00086101280.017
defense responseGO:00069521940.017
cell adhesionGO:00071551100.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
cytokine productionGO:0001816610.017
fatty acid metabolic processGO:0006631990.017
positive regulation of protein metabolic processGO:00512471780.017
regulation of anatomical structure sizeGO:00900661350.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
hepaticobiliary system developmentGO:0061008900.017
negative regulation of molecular functionGO:00440921330.017
dna metabolic processGO:0006259960.017
organ morphogenesisGO:0009887750.017
positive regulation of signal transductionGO:00099671750.017
protein localizationGO:00081041910.016
regulation of cell adhesionGO:0030155520.016
immune system processGO:00023762040.016
regulation of anatomical structure morphogenesisGO:00226031410.016
fatty acid biosynthetic processGO:0006633330.016
leukocyte proliferationGO:0070661290.016
protein complex biogenesisGO:00702712630.016
regulation of phosphate metabolic processGO:00192203490.016
positive regulation of neuron differentiationGO:00456661260.016
protein complex assemblyGO:00064612630.016
spermatogenesisGO:0007283990.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
response to decreased oxygen levelsGO:00362932370.016
cellular modified amino acid metabolic processGO:0006575610.016
regulation of neuron deathGO:19012141150.016
negative regulation of cell proliferationGO:00082851190.016
positive regulation of rna metabolic processGO:00512542030.016
epithelial cell differentiationGO:0030855710.016
inflammatory responseGO:00069541500.015
muscle system processGO:00030121150.015
cellular response to abiotic stimulusGO:0071214850.015
multicellular organismal homeostasisGO:0048871490.015
salivary gland developmentGO:000743130.015
cellular response to steroid hormone stimulusGO:0071383930.015
regulation of response to external stimulusGO:00321011060.015
amino acid transportGO:0006865700.015
positive regulation of cell developmentGO:00107201760.015
cell projection morphogenesisGO:00488581230.015
cellular homeostasisGO:00197252520.015
autophagic cell deathGO:004810240.015
regenerationGO:00310991630.015
smooth muscle cell proliferationGO:0048659770.015
positive regulation of secretionGO:00510471400.015
nucleotide metabolic processGO:00091172790.015
positive regulation of gene expressionGO:00106282440.015
negative regulation of transportGO:00510511360.015
response to hydrogen peroxideGO:0042542890.015
positive regulation of endothelial cell migrationGO:001059540.015
regulation of cytokine productionGO:0001817560.015
sex differentiationGO:00075481130.015
membrane organizationGO:0061024940.015
motor neuron axon guidanceGO:000804510.015
renal system developmentGO:0072001670.014
positive regulation of cellular protein metabolic processGO:00322701670.014
positive regulation of phosphorus metabolic processGO:00105622620.014
positive regulation of smooth muscle cell proliferationGO:0048661510.014
cell substrate adhesionGO:0031589290.014
regulation of organelle organizationGO:0033043800.014
positive regulation of cell migrationGO:0030335960.014
head developmentGO:00603222470.014
gonad developmentGO:00084061040.014
negative regulation of secretion by cellGO:1903531720.014
response to insulinGO:00328681330.014
immune response regulating signaling pathwayGO:0002764190.014
cellular response to extracellular stimulusGO:0031668730.014
amide transportGO:00428861050.014
response to purine containing compoundGO:00140741260.014
tissue regenerationGO:0042246360.014
leukocyte mediated immunityGO:0002443280.014
g protein coupled receptor signaling pathwayGO:00071862420.013
regulation of blood vessel sizeGO:0050880890.013
regulation of molecular functionGO:00650093980.013
cellular response to peptide hormone stimulusGO:00713751200.013
organelle organizationGO:00069962660.013
negative regulation of protein metabolic processGO:00512481140.013
positive regulation of cell projection organizationGO:00313461110.013
salivary gland morphogenesisGO:000743510.013
regulation of body fluid levelsGO:0050878900.013
protein complex subunit organizationGO:00718223020.013
positive regulation of protein phosphorylationGO:00019341350.013
positive regulation of neurogenesisGO:00507691650.013
regulation of phosphorus metabolic processGO:00511743490.013
negative regulation of response to stimulusGO:00485851550.013
positive regulation of phosphate metabolic processGO:00459372620.013
cell morphogenesis involved in neuron differentiationGO:00486671060.013
regulation of muscle system processGO:0090257790.013
cellular response to alcoholGO:0097306870.013
alcohol metabolic processGO:0006066770.013
organonitrogen compound catabolic processGO:19015651790.013
positive regulation of programmed cell deathGO:00430681570.013
steroid metabolic processGO:0008202730.013
neuron apoptotic processGO:0051402880.013
single organism cellular localizationGO:19025801020.013
regulation of membrane potentialGO:00423911100.012
mesoderm developmentGO:000749820.012
embryonic pattern specificationGO:000988010.012
fatty acid derivative metabolic processGO:1901568380.012
muscle tissue developmentGO:0060537580.012
synaptic vesicle endocytosisGO:004848840.012
monocarboxylic acid biosynthetic processGO:0072330480.012
positive regulation of cell deathGO:00109421840.012
nucleoside phosphate biosynthetic processGO:19012931020.012
peptide hormone secretionGO:0030072840.012
regulation of tube sizeGO:0035150890.012
anterior posterior pattern specificationGO:000995210.012
positive regulation of transcription dna templatedGO:00458931970.012
cellular response to insulin stimulusGO:0032869810.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
neurological system processGO:00508772190.012
negative regulation of secretionGO:0051048820.012
insulin secretionGO:0030073690.012
gland developmentGO:00487321550.012
single organismal cell cell adhesionGO:0016337420.012
cellular component movementGO:00069282480.012
regulation of mapk cascadeGO:00434081160.012
mapk cascadeGO:00001651400.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
hormone secretionGO:00468791150.012
neuron developmentGO:00486662860.012
cell activation involved in immune responseGO:0002263160.012
neuron projection morphogenesisGO:00488121220.012
regulation of epithelial cell proliferationGO:0050678490.012
muscle organ developmentGO:0007517500.012
regulation of homotypic cell cell adhesionGO:003411040.012
circulatory system developmentGO:00723591340.012
heart morphogenesisGO:000300730.012
respiratory system developmentGO:0060541450.011
response to metal ionGO:00100382530.011
regulation of hormone secretionGO:00468831060.011
ribose phosphate metabolic processGO:00196932350.011
calcium ion transportGO:00068161310.011
cytokine biosynthetic processGO:004208930.011
endocytosisGO:0006897840.011
development of primary sexual characteristicsGO:00451371070.011
regulation of lipid biosynthetic processGO:0046890380.011
positive regulation of neuron projection developmentGO:0010976990.011
response to activityGO:0014823730.011
vascular process in circulatory systemGO:0003018960.011
cellular amide metabolic processGO:0043603440.011
response to starvationGO:0042594590.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
liver developmentGO:0001889900.011
positive regulation of immune system processGO:0002684900.011
cellular response to oxidative stressGO:0034599760.011
positive regulation of kinase activityGO:0033674770.011
cell motilityGO:00488702020.011
organelle localizationGO:0051640550.011
cellular response to lipidGO:00713962010.011
cell morphogenesis involved in differentiationGO:00009041190.011
positive regulation of locomotionGO:00400171020.011
response to fatty acidGO:0070542650.011
regulation of b cell mediated immunityGO:000271220.011
regulation of response to woundingGO:1903034690.011
exocytosisGO:0006887600.011
regulation of endocytosisGO:0030100420.011
macromolecular complex subunit organizationGO:00439333390.011
multicellular organismal signalingGO:0035637440.011
axis specificationGO:000979840.011
ion homeostasisGO:00508012120.011
negative regulation of rna biosynthetic processGO:19026791180.011
regulation of immune responseGO:0050776550.010
regulation of ion transmembrane transportGO:00347651210.010
negative regulation of macromolecule biosynthetic processGO:00105581480.010
muscle contractionGO:0006936880.010
tube developmentGO:0035295890.010
protein maturationGO:0051604680.010
establishment of organelle localizationGO:0051656370.010
positive regulation of transferase activityGO:0051347810.010
single organism organelle organizationGO:19025891800.010
hair cycle processGO:002240520.010
regulation of synaptic transmissionGO:00508041410.010
decidualizationGO:0046697140.010
negative regulation of cellular protein metabolic processGO:00322691060.010
gastrulationGO:000736920.010
negative regulation of neuron deathGO:1901215690.010
regulation of cell morphogenesisGO:0022604770.010
negative regulation of cellular component organizationGO:0051129830.010
negative regulation of neurogenesisGO:0050768780.010

Lgmn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.068
disease of anatomical entityDOID:700.068
nervous system diseaseDOID:86300.045
disease of metabolismDOID:001466700.027
inherited metabolic disorderDOID:65500.026
sensory system diseaseDOID:005015500.018
connective tissue diseaseDOID:6500.013
immune system diseaseDOID:291400.012
central nervous system diseaseDOID:33100.011