Rattus norvegicus

83 known processes

Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

(Aliases: Dmt1,Nramp2)

Slc11a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell projection organizationGO:00300303020.066
response to inorganic substanceGO:00100353770.058
chemical homeostasisGO:00488782920.056
oxoacid metabolic processGO:00434362900.054
response to extracellular stimulusGO:00099913800.053
carboxylic acid metabolic processGO:00197522890.052
single organism biosynthetic processGO:00447113420.052
cation transportGO:00068123820.050
organic acid metabolic processGO:00060822920.050
response to nutrient levelsGO:00316673700.048
cellular response to oxygen containing compoundGO:19017013860.047
secretionGO:00469033070.045
organonitrogen compound biosynthetic processGO:19015661670.044
organophosphate metabolic processGO:00196373700.041
central nervous system developmentGO:00074173110.041
cellular response to stressGO:00335542690.040
macromolecular complex subunit organizationGO:00439333390.040
vesicle mediated transportGO:00161921810.040
neuron projection developmentGO:00311752730.039
cellular amino acid metabolic processGO:00065201070.039
monocarboxylic acid metabolic processGO:00327871520.039
macromolecule localizationGO:00330362520.038
gland developmentGO:00487321550.036
regulation of neurogenesisGO:00507672470.036
regulation of cell proliferationGO:00421273590.036
lipid biosynthetic processGO:00086101280.036
lipid metabolic processGO:00066292830.036
anion transportGO:00068201780.035
regulation of cellular component organizationGO:00511283680.035
protein localizationGO:00081041910.035
organophosphate biosynthetic processGO:00904071430.034
regulation of cell developmentGO:00602842630.033
cell cell signalingGO:00072673350.033
hepaticobiliary system developmentGO:0061008900.033
regulation of apoptotic processGO:00429813350.032
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.032
regulation of programmed cell deathGO:00430673410.032
Human
positive regulation of developmental processGO:00510942830.032
response to hypoxiaGO:00016662310.032
ion transmembrane transportGO:00342203650.032
neuron differentiationGO:00301823680.031
programmed cell deathGO:00125013920.031
Human
reproductive processGO:00224143720.030
positive regulation of multicellular organismal processGO:00512403870.030
regulation of multicellular organismal developmentGO:20000263760.030
ras protein signal transductionGO:0007265290.030
regulation of transcription dna templatedGO:00063553740.030
protein transportGO:00150311320.029
secretion by cellGO:00329402480.028
cellular amine metabolic processGO:0044106380.028
cellular protein localizationGO:00346131220.028
inorganic ion transmembrane transportGO:00986602290.028
cellular component biogenesisGO:00440853680.028
ion homeostasisGO:00508012120.028
macromolecular complex assemblyGO:00650032730.028
homeostatic processGO:00425923310.028
liver developmentGO:0001889900.027
signal releaseGO:00230611450.027
regulation of nervous system developmentGO:00519602640.027
organic anion transportGO:00157111320.027
protein complex biogenesisGO:00702712630.027
intracellular signal transductionGO:00355563140.026
multi organism reproductive processGO:00447032620.026
agingGO:00075682410.026
positive regulation of cell differentiationGO:00455972170.026
positive regulation of nervous system developmentGO:00519621780.026
response to decreased oxygen levelsGO:00362932370.026
amine metabolic processGO:0009308380.026
response to peptideGO:19016522920.025
rna biosynthetic processGO:00327743800.025
regulation of rna metabolic processGO:00512523910.025
synaptic transmissionGO:00072682350.025
response to oxygen levelsGO:00704822650.025
regulation of cellular localizationGO:00603412630.025
regulation of neuron projection developmentGO:00109751610.025
transmembrane transportGO:00550854120.025
cellular response to endogenous stimulusGO:00714953770.024
nucleobase containing small molecule metabolic processGO:00550863160.024
single organism carbohydrate metabolic processGO:00447231180.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
carbohydrate derivative metabolic processGO:19011353460.024
carboxylic acid transportGO:00469421150.024
positive regulation of neurogenesisGO:00507691650.024
reproductionGO:00000032450.024
oxidation reduction processGO:00551143040.024
nucleotide metabolic processGO:00091172790.024
proteolysisGO:00065081750.023
Human
regulation of catalytic activityGO:00507903040.022
Human
cellular lipid metabolic processGO:00442552080.022
positive regulation of cell developmentGO:00107201760.022
response to peptide hormoneGO:00434342780.022
negative regulation of metabolic processGO:00098923310.022
multicellular organismal reproductive processGO:00486092330.022
regulation of cellular ketone metabolic processGO:0010565270.022
cofactor metabolic processGO:0051186950.022
cellular chemical homeostasisGO:00550822470.022
cellular component movementGO:00069282480.021
negative regulation of cellular metabolic processGO:00313242810.021
cellular response to peptideGO:19016531330.021
catabolic processGO:00090563510.021
regulation of signal transductionGO:00099663180.021
ribose phosphate metabolic processGO:00196932350.021
protein complex subunit organizationGO:00718223020.021
regulation of cell projection organizationGO:00313441750.021
single organism reproductive processGO:00447022970.021
protein complex assemblyGO:00064612630.021
regulation of phosphate metabolic processGO:00192203490.021
carbohydrate metabolic processGO:00059751300.021
positive regulation of cellular biosynthetic processGO:00313282950.021
cellular macromolecule localizationGO:00707271220.021
negative regulation of macromolecule metabolic processGO:00106052600.020
regulation of rna biosynthetic processGO:20011413810.020
regulation of neuron differentiationGO:00456642080.020
cellular response to growth factor stimulusGO:00713631620.020
regulation of anatomical structure sizeGO:00900661350.020
nitrogen compound transportGO:00717052290.020
head developmentGO:00603222470.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
transcription dna templatedGO:00063513770.020
cellular ion homeostasisGO:00068731840.020
positive regulation of cell proliferationGO:00082842490.020
response to acid chemicalGO:00011012220.020
regulation of secretionGO:00510462240.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
carbohydrate derivative biosynthetic processGO:19011371240.020
cellular response to external stimulusGO:00714961180.020
response to lipopolysaccharideGO:00324961910.020
rhythmic processGO:00485111560.020
cellular ketone metabolic processGO:0042180510.019
multicellular organism reproductionGO:00325042330.019
cell motilityGO:00488702020.019
cation homeostasisGO:00550801950.019
response to ethanolGO:00454711620.019
organelle organizationGO:00069962660.019
cellular homeostasisGO:00197252520.019
metal ion homeostasisGO:00550651860.019
regulation of ion transportGO:00432692450.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
brain developmentGO:00074202470.019
single organism cellular localizationGO:19025801020.019
positive regulation of cellular amino acid metabolic processGO:004576410.018
metal ion transportGO:00300012890.018
cellular catabolic processGO:00442482950.018
regulation of molecular functionGO:00650093980.018
Human
protein phosphorylationGO:00064683450.018
divalent inorganic cation homeostasisGO:00725071650.018
Yeast
regulation of cellular amino acid metabolic processGO:000652120.018
embryonic pattern specificationGO:000988010.018
alpha amino acid metabolic processGO:1901605710.018
blood circulationGO:00080151830.017
rna metabolic processGO:00160704060.017
gastrulationGO:000736920.017
single organism intracellular transportGO:19025821660.017
response to insulinGO:00328681330.017
anion transmembrane transportGO:0098656770.017
establishment of protein localizationGO:00451841410.017
cellular response to nitrogen compoundGO:19016992100.017
response to growth factorGO:00708481890.017
organic substance catabolic processGO:19015753160.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
response to nutrientGO:00075842480.017
positive regulation of cellular component organizationGO:00511302000.017
intracellular transportGO:00469071850.017
negative regulation of biosynthetic processGO:00098901680.017
nucleic acid templated transcriptionGO:00976593790.016
positive regulation of response to stimulusGO:00485842850.016
axis specificationGO:000979840.016
cellular component assemblyGO:00226073600.016
small molecule biosynthetic processGO:00442831240.016
negative regulation of gene expressionGO:00106291990.016
cytoplasmic transportGO:00164821150.016
coenzyme metabolic processGO:0006732860.016
positive regulation of biosynthetic processGO:00098913190.016
negative regulation of cellular biosynthetic processGO:00313271610.016
eye morphogenesisGO:004859240.016
response to carbohydrateGO:00097431830.016
regulation of cellular component movementGO:00512701500.016
hormone secretionGO:00468791150.016
response to radiationGO:00093141370.016
cellular response to organonitrogen compoundGO:00714171970.016
negative regulation of cell communicationGO:00106481580.016
negative regulation of cell deathGO:00605482290.016
cellular response to hormone stimulusGO:00328702470.016
response to bacteriumGO:00096172000.016
response to estrogenGO:00436272320.016
protein oligomerizationGO:00512591910.016
negative regulation of multicellular organismal processGO:00512412030.016
circulatory system processGO:00030131830.016
neuron developmentGO:00486662860.016
membrane organizationGO:0061024940.016
small gtpase mediated signal transductionGO:0007264360.016
response to hexoseGO:00097461440.015
positive regulation of phosphorus metabolic processGO:00105622620.015
asymmetric protein localizationGO:000810520.015
single organism membrane organizationGO:0044802740.015
organic acid transportGO:00158491160.015
anterior posterior pattern specificationGO:000995210.015
purine containing compound metabolic processGO:00725212530.015
monovalent inorganic cation transportGO:00156721720.015
Human Yeast
regulation of cellular amine metabolic processGO:003323880.015
cellular response to organic cyclic compoundGO:00714072020.015
ribonucleotide biosynthetic processGO:0009260850.015
sexual reproductionGO:00199531480.015
regulation of secretion by cellGO:19035302080.015
nucleoside metabolic processGO:00091161790.015
tissue developmentGO:00098882520.015
nucleoside phosphate metabolic processGO:00067532830.015
regulation of synaptic transmissionGO:00508041410.015
g protein coupled receptor signaling pathwayGO:00071862420.015
regulation of nucleotide metabolic processGO:00061401170.015
cellular metal ion homeostasisGO:00068751720.015
regulation of cell differentiationGO:00455953200.015
positive regulation of programmed cell deathGO:00430681570.015
Human
peptide transportGO:0015833970.015
negative regulation of programmed cell deathGO:00430691830.015
transcription from rna polymerase ii promoterGO:00063662520.015
cellular response to insulin stimulusGO:0032869810.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
anatomical structure morphogenesisGO:00096532980.015
response to metal ionGO:00100382530.015
cellular response to cytokine stimulusGO:00713451270.015
response to retinoic acidGO:0032526630.015
neurological system processGO:00508772190.015
single organism catabolic processGO:00447122830.014
regulation of intracellular signal transductionGO:19025312180.014
regulation of phosphorus metabolic processGO:00511743490.014
defense responseGO:00069521940.014
forebrain developmentGO:0030900980.014
regulation of system processGO:00440572080.014
ribonucleotide metabolic processGO:00092592310.014
cellular component morphogenesisGO:00329891550.014
positive regulation of apoptotic processGO:00430651540.014
Human
response to cytokineGO:00340972150.014
purine nucleotide metabolic processGO:00061632290.014
cellular response to peptide hormone stimulusGO:00713751200.014
response to oxidative stressGO:00069791860.014
Human
cellular cation homeostasisGO:00300031800.014
calcium ion homeostasisGO:00550741620.014
positive regulation of cell communicationGO:00106472710.014
ribose phosphate biosynthetic processGO:0046390870.014
positive regulation of signalingGO:00230562700.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
amide transportGO:00428861050.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
Yeast
cell migrationGO:00164771970.014
locomotionGO:00400112370.014
regulation of phosphorylationGO:00423252480.014
organic hydroxy compound metabolic processGO:19016151150.014
positive regulation of cellular amine metabolic processGO:003324030.013
regulation of hormone levelsGO:00108171870.013
chemosensory behaviorGO:000763520.013
apoptotic processGO:00069153810.013
Human
response to monosaccharideGO:00342841590.013
olfactory behaviorGO:004204820.013
positive regulation of ion transportGO:0043270940.013
generation of precursor metabolites and energyGO:0006091620.013
peptide secretionGO:0002790860.013
positive regulation of phosphate metabolic processGO:00459372620.013
gamete generationGO:00072761240.013
hormone transportGO:00099141210.013
sex differentiationGO:00075481130.013
regulation of protein metabolic processGO:00512462890.013
Human
glycosyl compound metabolic processGO:19016571820.013
positive regulation of secretion by cellGO:19035321280.013
multicellular organism growthGO:003526410.013
negative regulation of innate immune responseGO:004582440.013
purine ribonucleoside metabolic processGO:00461281680.013
circadian rhythmGO:0007623880.013
purine containing compound biosynthetic processGO:0072522850.013
cellular carbohydrate metabolic processGO:0044262720.013
positive regulation of transportGO:00510502450.013
multicellular organismal homeostasisGO:0048871490.013
Human
cellular response to lipidGO:00713962010.013
regulation of peptide secretionGO:0002791820.013
response to ionizing radiationGO:0010212590.013
response to other organismGO:00517072200.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
tube developmentGO:0035295890.012
positive regulation of cell projection organizationGO:00313461110.012
actin cytoskeleton organizationGO:0030036730.012
response to transition metal nanoparticleGO:19902671220.012
regulation of cell cycleGO:0051726730.012
cellular modified amino acid metabolic processGO:0006575610.012
regulation of hormone secretionGO:00468831060.012
epithelial cell differentiationGO:0030855710.012
endoplasmic reticulum organizationGO:000702910.012
localization of cellGO:00516742020.012
regulation of anatomical structure morphogenesisGO:00226031410.012
ribonucleoside metabolic processGO:00091191740.012
organonitrogen compound catabolic processGO:19015651790.012
neuron deathGO:00709971270.012
inflammatory responseGO:00069541500.012
cellular calcium ion homeostasisGO:00068741600.012
negative regulation of cell proliferationGO:00082851190.012
negative regulation of apoptotic processGO:00430661810.012
intracellular protein transportGO:0006886790.012
developmental process involved in reproductionGO:00030061590.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
negative regulation of transportGO:00510511360.012
response to molecule of bacterial originGO:00022371940.012
response to glucoseGO:00097491360.012
response to biotic stimulusGO:00096072260.012
positive regulation of rna metabolic processGO:00512542030.011
cation transmembrane transportGO:00986552630.011
positive regulation of neuron differentiationGO:00456661260.011
negative regulation of response to stimulusGO:00485851550.011
negative regulation of rna metabolic processGO:00512531230.011
purine nucleoside metabolic processGO:00422781690.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
response to reactive oxygen speciesGO:00003021200.011
positive regulation of nucleotide metabolic processGO:0045981910.011
purine ribonucleotide metabolic processGO:00091502270.011
positive regulation of cellular protein metabolic processGO:00322701670.011
Human
negative regulation of signalingGO:00230571570.011
positive regulation of gene expressionGO:00106282440.011
peptide hormone secretionGO:0030072840.011
cellular response to reactive oxygen speciesGO:0034614550.011
nucleoside triphosphate metabolic processGO:00091411440.011
actin filament based processGO:0030029860.011
regulation of peptide transportGO:0090087870.011
protein homooligomerizationGO:0051260910.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
regulation of body fluid levelsGO:0050878900.011
positive regulation of rna biosynthetic processGO:19026801970.011
reactive oxygen species biosynthetic processGO:190340980.011
sensory organ developmentGO:0007423740.011
regulation of purine nucleotide metabolic processGO:19005421150.011
dephosphorylationGO:0016311980.011
response to hydrogen peroxideGO:0042542890.011
positive regulation of transcription dna templatedGO:00458931970.011
negative regulation of molecular functionGO:00440921330.011
response to toxic substanceGO:00096361330.011
regulation of neuron deathGO:19012141150.011
salivary gland developmentGO:000743130.011
regulation of locomotionGO:00400121480.011
potassium ion transportGO:0006813970.011
negative regulation of developmental processGO:00510931250.011
positive regulation of signal transductionGO:00099671750.011
spermatogenesisGO:0007283990.011
regulation of protein phosphorylationGO:00019321830.011
glycogen metabolic processGO:0005977230.011
peptidyl amino acid modificationGO:00181931260.011
gonad developmentGO:00084061040.010
cellular response to extracellular stimulusGO:0031668730.010
response to external biotic stimulusGO:00432072210.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
sodium ion transmembrane transportGO:0035725670.010
glucose metabolic processGO:0006006520.010
embryonic axis specificationGO:000057810.010
negative regulation of rna biosynthetic processGO:19026791180.010
nucleoside phosphate biosynthetic processGO:19012931020.010
carbohydrate homeostasisGO:0033500750.010
heart morphogenesisGO:000300730.010
response to estradiolGO:00323551640.010
negative regulation of signal transductionGO:0009968830.010
growthGO:00400071650.010
cellular amide metabolic processGO:0043603440.010
action potentialGO:0001508540.010
response to amineGO:0014075460.010
spindle organizationGO:000705120.010
organic acid biosynthetic processGO:0016053830.010
reproductive structure developmentGO:00486081280.010
regulation of growthGO:00400081050.010
glucose homeostasisGO:0042593750.010
male gamete generationGO:0048232990.010

Slc11a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
Human
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.020
central nervous system diseaseDOID:33100.014
musculoskeletal system diseaseDOID:1700.013
disease of cellular proliferationDOID:1456600.010