Rattus norvegicus

0 known processes

Slc11a1

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

(Aliases: MGC124692,Itg,Bcg,Lsh,Nramp1)

Slc11a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of natural killer cell mediated immunityGO:000271640.050
intracellular signal transductionGO:00355563140.043
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.041
transmembrane transportGO:00550854120.038
Human Yeast Rat
secretionGO:00469033070.038
regulation of molecular functionGO:00650093980.037
programmed cell deathGO:00125013920.037
regulation of cell proliferationGO:00421273590.036
organophosphate metabolic processGO:00196373700.036
response to nutrient levelsGO:00316673700.036
apoptotic processGO:00069153810.034
regulation of apoptotic processGO:00429813350.034
response to extracellular stimulusGO:00099913800.033
nitrogen compound transportGO:00717052290.033
homeostatic processGO:00425923310.033
Human Yeast Rat
protein phosphorylationGO:00064683450.033
regulation of phosphate metabolic processGO:00192203490.032
negative regulation of innate immune responseGO:004582440.032
response to biotic stimulusGO:00096072260.031
Human
cellular component movementGO:00069282480.031
cell projection organizationGO:00300303020.031
metal ion transportGO:00300012890.031
Human Yeast Rat
response to inorganic substanceGO:00100353770.031
Rat
cell cell signalingGO:00072673350.030
cellular component biogenesisGO:00440853680.030
carbohydrate derivative metabolic processGO:19011353460.030
cation transportGO:00068123820.029
Human Yeast Rat
regulation of cell differentiationGO:00455953200.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
carboxylic acid metabolic processGO:00197522890.029
cellular response to oxygen containing compoundGO:19017013860.029
regulation of phosphorus metabolic processGO:00511743490.028
regulation of programmed cell deathGO:00430673410.028
secretion by cellGO:00329402480.028
chemical homeostasisGO:00488782920.028
Human Yeast Rat
rna biosynthetic processGO:00327743800.028
immune system processGO:00023762040.028
response to other organismGO:00517072200.027
Human
regulation of multicellular organismal developmentGO:20000263760.027
regulation of secretion by cellGO:19035302080.027
response to external biotic stimulusGO:00432072210.027
Human
positive regulation of developmental processGO:00510942830.027
central nervous system developmentGO:00074173110.027
regulation of rna biosynthetic processGO:20011413810.027
negative regulation of metabolic processGO:00098923310.027
cellular amine metabolic processGO:0044106380.027
metal ion homeostasisGO:00550651860.026
Human Yeast Rat
catabolic processGO:00090563510.026
positive regulation of response to stimulusGO:00485842850.026
cation transmembrane transportGO:00986552630.026
Human Yeast Rat
positive regulation of cell communicationGO:00106472710.026
cellular component assemblyGO:00226073600.026
defense responseGO:00069521940.026
regulation of signal transductionGO:00099663180.026
positive regulation of cellular biosynthetic processGO:00313282950.026
macromolecular complex assemblyGO:00650032730.026
cation homeostasisGO:00550801950.026
Human Yeast Rat
positive regulation of cell proliferationGO:00082842490.026
rna metabolic processGO:00160704060.026
reproductive processGO:00224143720.026
organic acid metabolic processGO:00060822920.026
response to woundingGO:00096112540.026
regulation of catalytic activityGO:00507903040.026
regulation of cellular amino acid metabolic processGO:000652120.026
positive regulation of multicellular organismal processGO:00512403870.026
cellular homeostasisGO:00197252520.025
Human Yeast Rat
neuron differentiationGO:00301823680.025
positive regulation of biosynthetic processGO:00098913190.025
ion transmembrane transportGO:00342203650.025
Human Yeast Rat
regulation of cellular component organizationGO:00511283680.025
regulation of system processGO:00440572080.025
response to bacteriumGO:00096172000.025
Human
response to nutrientGO:00075842480.025
transcription dna templatedGO:00063513770.025
oxoacid metabolic processGO:00434362900.025
nucleic acid templated transcriptionGO:00976593790.025
response to hypoxiaGO:00016662310.025
Rat
regulation of cellular amine metabolic processGO:003323880.025
regulation of intracellular signal transductionGO:19025312180.025
negative regulation of cell deathGO:00605482290.025
g protein coupled receptor signaling pathwayGO:00071862420.025
regulation of secretionGO:00510462240.025
cellular cation homeostasisGO:00300031800.025
Human Yeast Rat
positive regulation of transportGO:00510502450.025
amine metabolic processGO:0009308380.025
regulation of ion transportGO:00432692450.024
negative regulation of cellular metabolic processGO:00313242810.024
localization of cellGO:00516742020.024
response to glucocorticoidGO:00513842230.024
nucleoside phosphate metabolic processGO:00067532830.024
cellular response to stressGO:00335542690.024
Rat
response to oxygen levelsGO:00704822650.024
Rat
positive regulation of phosphate metabolic processGO:00459372620.024
locomotionGO:00400112370.024
regulation of cellular protein metabolic processGO:00322682670.024
cell motilityGO:00488702020.024
purine containing compound metabolic processGO:00725212530.024
cellular catabolic processGO:00442482950.024
response to decreased oxygen levelsGO:00362932370.023
Rat
cellular ketone metabolic processGO:0042180510.023
positive regulation of phosphorus metabolic processGO:00105622620.023
regulation of cellular ketone metabolic processGO:0010565270.023
divalent inorganic cation homeostasisGO:00725071650.023
Human Yeast
protein localizationGO:00081041910.023
response to growth factorGO:00708481890.023
regulation of neurogenesisGO:00507672470.023
regulation of protein metabolic processGO:00512462890.023
positive regulation of signalingGO:00230562700.023
response to metal ionGO:00100382530.023
Rat
regulation of cellular localizationGO:00603412630.023
ion homeostasisGO:00508012120.023
Human Yeast Rat
regulation of rna metabolic processGO:00512523910.023
neurological system processGO:00508772190.023
immune responseGO:00069551040.023
neuron projection developmentGO:00311752730.023
protein complex biogenesisGO:00702712630.023
cell migrationGO:00164771970.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
response to peptideGO:19016522920.022
negative regulation of macromolecule metabolic processGO:00106052600.022
multi organism reproductive processGO:00447032620.022
positive regulation of nucleobase containing compound metabolic processGO:00459353190.022
cellular ion homeostasisGO:00068731840.022
Human Yeast Rat
cellular chemical homeostasisGO:00550822470.022
Human Yeast Rat
blood circulationGO:00080151830.022
negative regulation of response to stimulusGO:00485851550.022
positive regulation of cell differentiationGO:00455972170.022
nucleobase containing small molecule metabolic processGO:00550863160.022
regulation of phosphorylationGO:00423252480.021
ribose phosphate metabolic processGO:00196932350.021
protein complex subunit organizationGO:00718223020.021
agingGO:00075682410.021
cellular response to endogenous stimulusGO:00714953770.021
circulatory system processGO:00030131830.021
regulation of cell developmentGO:00602842630.021
regulation of transcription dna templatedGO:00063553740.021
positive regulation of protein metabolic processGO:00512471780.021
regulation of locomotionGO:00400121480.021
divalent metal ion transportGO:00708381320.021
Human Yeast Rat
cellular amino acid metabolic processGO:00065201070.021
regulation of cellular component movementGO:00512701500.021
organic substance catabolic processGO:19015753160.021
response to estrogenGO:00436272320.021
positive regulation of macromolecule biosynthetic processGO:00105572470.021
transcription from rna polymerase ii promoterGO:00063662520.020
response to molecule of bacterial originGO:00022371940.020
lipid metabolic processGO:00066292830.020
head developmentGO:00603222470.020
nucleotide metabolic processGO:00091172790.020
behaviorGO:00076102050.020
positive regulation of gene expressionGO:00106282440.020
ribonucleotide metabolic processGO:00092592310.020
positive regulation of secretion by cellGO:19035321280.020
response to cytokineGO:00340972150.020
Rat
positive regulation of molecular functionGO:00440932300.020
positive regulation of cellular amine metabolic processGO:003324030.019
cellular metal ion homeostasisGO:00068751720.019
Human Yeast Rat
macromolecular complex subunit organizationGO:00439333390.019
negative regulation of programmed cell deathGO:00430691830.019
regulation of immune system processGO:00026821230.019
t cell tolerance inductionGO:000251730.019
signal releaseGO:00230611450.019
inorganic ion transmembrane transportGO:00986602290.019
Human Rat
response to peptide hormoneGO:00434342780.019
purine nucleotide metabolic processGO:00061632290.019
single organism reproductive processGO:00447022970.019
reproductionGO:00000032450.019
cellular response to hormone stimulusGO:00328702470.019
response to ketoneGO:19016541820.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
regulation of protein modification processGO:00313991940.019
multicellular organismal reproductive processGO:00486092330.019
calcium ion transportGO:00068161310.019
positive regulation of rna metabolic processGO:00512542030.019
cellular response to organonitrogen compoundGO:00714171970.018
purine ribonucleotide metabolic processGO:00091502270.018
protein complex assemblyGO:00064612630.018
regulation of protein phosphorylationGO:00019321830.018
positive regulation of cell deathGO:00109421840.018
cellular response to nitrogen compoundGO:19016992100.018
inflammatory responseGO:00069541500.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
Human Yeast
cellular response to lipidGO:00713962010.018
positive regulation of intracellular signal transductionGO:19025331380.018
regulation of hormone levelsGO:00108171870.018
anatomical structure morphogenesisGO:00096532980.018
response to ethanolGO:00454711620.018
single organism catabolic processGO:00447122830.018
neuron developmentGO:00486662860.018
response to acid chemicalGO:00011012220.018
regulation of nervous system developmentGO:00519602640.018
negative regulation of nitrogen compound metabolic processGO:00511721610.018
positive regulation of phosphorylationGO:00423271770.018
anion transportGO:00068201780.018
single organism biosynthetic processGO:00447113420.017
response to corticosteroidGO:00319602350.017
tissue developmentGO:00098882520.017
brain developmentGO:00074202470.017
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
response to oxidative stressGO:00069791860.017
synaptic transmissionGO:00072682350.017
cellular calcium ion homeostasisGO:00068741600.017
negative regulation of apoptotic processGO:00430661810.017
multicellular organism reproductionGO:00325042330.017
positive regulation of catalytic activityGO:00430851840.017
macromolecule localizationGO:00330362520.017
positive regulation of tolerance inductionGO:000264510.017
monovalent inorganic cation transportGO:00156721720.017
Human Yeast
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
response to lipopolysaccharideGO:00324961910.017
heterocycle catabolic processGO:00467001670.017
positive regulation of rna biosynthetic processGO:19026801970.016
regulation of cell motilityGO:20001451310.016
response to mechanical stimulusGO:00096121340.016
positive regulation of apoptotic processGO:00430651540.016
nucleoside metabolic processGO:00091161790.016
cellular nitrogen compound catabolic processGO:00442701630.016
ras protein signal transductionGO:0007265290.016
regulation of cell migrationGO:00303341280.016
positive regulation of secretionGO:00510471400.016
positive regulation of protein modification processGO:00314011420.016
calcium ion homeostasisGO:00550741620.016
positive regulation of cell developmentGO:00107201760.016
regulation of tolerance induction dependent upon immune responseGO:000265210.016
positive regulation of transcription dna templatedGO:00458931970.016
positive regulation of cellular component organizationGO:00511302000.016
ribonucleoside metabolic processGO:00091191740.016
negative regulation of cell communicationGO:00106481580.016
cellular response to cytokine stimulusGO:00713451270.016
Rat
divalent inorganic cation transportGO:00725111340.016
Human Yeast Rat
muscle system processGO:00030121150.016
positive regulation of cellular protein metabolic processGO:00322701670.016
regulation of membrane potentialGO:00423911100.015
negative regulation of molecular functionGO:00440921330.015
regulation of anatomical structure sizeGO:00900661350.015
protein oligomerizationGO:00512591910.015
cellular response to external stimulusGO:00714961180.015
positive regulation of nervous system developmentGO:00519621780.015
small gtpase mediated signal transductionGO:0007264360.015
cellular response to organic cyclic compoundGO:00714072020.015
single organism intracellular transportGO:19025821660.015
sensory perceptionGO:00076001010.015
cytosolic calcium ion homeostasisGO:00514801400.015
positive regulation of protein phosphorylationGO:00019341350.015
cellular response to growth factor stimulusGO:00713631620.015
negative regulation of signalingGO:00230571570.015
anterior posterior pattern specificationGO:000995210.015
organic cyclic compound catabolic processGO:19013611750.015
negative regulation of gene expressionGO:00106291990.015
response to estradiolGO:00323551640.015
growthGO:00400071650.015
positive regulation of programmed cell deathGO:00430681570.015
cellular lipid metabolic processGO:00442552080.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
response to radiationGO:00093141370.015
regulation of neuron differentiationGO:00456642080.015
positive regulation of tolerance induction dependent upon immune responseGO:000265410.015
negative regulation of multicellular organismal processGO:00512412030.015
organelle organizationGO:00069962660.014
nucleoside triphosphate metabolic processGO:00091411440.014
organonitrogen compound biosynthetic processGO:19015661670.014
nucleobase containing compound catabolic processGO:00346551520.014
inorganic cation transmembrane transportGO:00986622020.014
Human Rat
mapk cascadeGO:00001651400.014
aromatic compound catabolic processGO:00194391680.014
cell morphogenesis involved in differentiationGO:00009041190.014
regulation of neuron deathGO:19012141150.014
regulation of homeostatic processGO:00328441010.014
negative regulation of transportGO:00510511360.014
cell activationGO:0001775970.014
purine ribonucleoside metabolic processGO:00461281680.014
regulation of kinase activityGO:00435491170.014
organophosphate catabolic processGO:00464341480.014
innate immune responseGO:0045087350.014
sexual reproductionGO:00199531480.014
cell morphogenesisGO:00009021420.014
regulation of transferase activityGO:00513381230.014
negative regulation of secretionGO:0051048820.014
regulation of cell projection organizationGO:00313441750.014
glycosyl compound metabolic processGO:19016571820.013
female pregnancyGO:00075651220.013
nucleotide catabolic processGO:00091661390.013
response to reactive oxygen speciesGO:00003021200.013
response to toxic substanceGO:00096361330.013
axis specificationGO:000979840.013
multi multicellular organism processGO:00447061380.013
amide transportGO:00428861050.013
negative regulation of cell proliferationGO:00082851190.013
reactive oxygen species metabolic processGO:0072593370.013
peptide transportGO:0015833970.013
positive regulation of neurogenesisGO:00507691650.013
regulation of hormone secretionGO:00468831060.013
carbohydrate derivative catabolic processGO:19011361470.013
purine nucleoside metabolic processGO:00422781690.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
positive regulation of neuron differentiationGO:00456661260.013
heart morphogenesisGO:000300730.013
tolerance induction dependent upon immune responseGO:000246120.013
wound healingGO:00420601220.013
cellular response to peptideGO:19016531330.013
establishment of protein localizationGO:00451841410.013
regulation of synaptic transmissionGO:00508041410.013
sensory perception of painGO:0019233730.013
cell adhesionGO:00071551100.013
proteolysisGO:00065081750.013
response to vitaminGO:00332731310.013
negative regulation of biosynthetic processGO:00098901680.013
regulation of metal ion transportGO:00109591180.013
nucleoside phosphate catabolic processGO:19012921400.013
embryonic pattern specificationGO:000988010.013
regulation of neuron projection developmentGO:00109751610.013
neuron deathGO:00709971270.013
hormone secretionGO:00468791150.013
cellular macromolecule localizationGO:00707271220.013
organic anion transportGO:00157111320.013
regulation of blood circulationGO:19035221100.012
positive regulation of signal transductionGO:00099671750.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
positive regulation of cell migrationGO:0030335960.012
organic acid transportGO:00158491160.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
muscle contractionGO:0006936880.012
glycosyl compound catabolic processGO:19016581260.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
gland developmentGO:00487321550.012
potassium ion transportGO:0006813970.012
developmental process involved in reproductionGO:00030061590.012
regulation of response to stressGO:00801341260.012
regulation of anatomical structure morphogenesisGO:00226031410.012
organophosphate biosynthetic processGO:00904071430.012
response to glucoseGO:00097491360.012
reactive nitrogen species metabolic processGO:200105710.012
regulation of hydrolase activityGO:00513361430.012
ribonucleotide catabolic processGO:00092611360.012
purine nucleotide catabolic processGO:00061951360.012
response to hexoseGO:00097461440.012
purine containing compound catabolic processGO:00725231380.012
response to carbohydrateGO:00097431830.012
nucleoside triphosphate catabolic processGO:00091431230.012
cytokine biosynthetic processGO:004208930.012
single organism carbohydrate metabolic processGO:00447231180.012
reactive oxygen species biosynthetic processGO:190340980.012
circulatory system developmentGO:00723591340.012
regulation of tube sizeGO:0035150890.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
oxidation reduction processGO:00551143040.012
response to transition metal nanoparticleGO:19902671220.012
Rat
positive regulation of t cell mediated cytotoxicityGO:000191640.012
purine ribonucleotide catabolic processGO:00091541360.012
actin filament based processGO:0030029860.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
eye morphogenesisGO:004859240.011
negative regulation of transcription dna templatedGO:00458921160.011
signal transduction by phosphorylationGO:00230141440.011
leukocyte cell cell adhesionGO:000715940.011
carbohydrate derivative biosynthetic processGO:19011371240.011
protein transportGO:00150311320.011
negative regulation of cellular biosynthetic processGO:00313271610.011
cardiovascular system developmentGO:00723581340.011
hormone transportGO:00099141210.011
response to monosaccharideGO:00342841590.011
sequestering of calcium ionGO:005120880.011
organonitrogen compound catabolic processGO:19015651790.011
cellular component morphogenesisGO:00329891550.011
regenerationGO:00310991630.011
cell type specific apoptotic processGO:00972851340.011
nucleoside catabolic processGO:00091641260.011
regulation of tolerance induction to nonself antigenGO:000265510.011
vesicle mediated transportGO:00161921810.011
positive regulation of locomotionGO:00400171020.011
negative regulation of catalytic activityGO:00430861030.011
regulation of purine nucleotide metabolic processGO:19005421150.011
positive regulation of immune system processGO:0002684900.011
regulation of peptide transportGO:0090087870.011
multicellular organismal signalingGO:0035637440.011
regulation of cytokine biosynthetic processGO:004203530.011
single organism organelle organizationGO:19025891800.011
carboxylic acid transportGO:00469421150.011
membrane organizationGO:0061024940.011
negative regulation of developmental processGO:00510931250.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
regulation of protein kinase activityGO:00458591050.011
sequestering of metal ionGO:005123890.011
cellular response to steroid hormone stimulusGO:0071383930.011
negative regulation of rna biosynthetic processGO:19026791180.011
vascular process in circulatory systemGO:0003018960.011
lipid biosynthetic processGO:00086101280.011
positive regulation of cellular component movementGO:00512721020.011
regulation of calcium ion transportGO:0051924770.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
purine nucleoside catabolic processGO:00061521240.011
dephosphorylationGO:0016311980.011
response to hydrogen peroxideGO:0042542890.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
negative regulation of rna metabolic processGO:00512531230.011
intracellular transportGO:00469071850.011
negative regulation of cell differentiationGO:0045596990.011
regulation of mapk cascadeGO:00434081160.011
positive regulation of cell projection organizationGO:00313461110.010
chromosome segregationGO:000705920.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
spindle organizationGO:000705120.010
biological adhesionGO:00226101100.010
response to alkaloidGO:00432791320.010
regulation of catabolic processGO:00098941130.010
peptide hormone secretionGO:0030072840.010
organic hydroxy compound transportGO:0015850770.010
rna localizationGO:000640340.010
negative regulation of secretion by cellGO:1903531720.010
gastrulationGO:000736920.010
peptidyl amino acid modificationGO:00181931260.010
sex differentiationGO:00075481130.010
response to insulinGO:00328681330.010
lipid storageGO:001991510.010
gamete generationGO:00072761240.010
regulation of canonical wnt signaling pathwayGO:006082840.010
insulin secretionGO:0030073690.010
organ regenerationGO:00311001010.010
positive regulation of transferase activityGO:0051347810.010
action potentialGO:0001508540.010
peptide secretionGO:0002790860.010
smooth muscle cell proliferationGO:0048659770.010
regulation of body fluid levelsGO:0050878900.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
regulation of defense responseGO:0031347680.010
transmission of nerve impulseGO:0019226420.010

Slc11a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
musculoskeletal system diseaseDOID:1700.015
disease of metabolismDOID:001466700.013
sensory system diseaseDOID:005015500.012
central nervous system diseaseDOID:33100.010