Rattus norvegicus

204 known processes

Shc1

SHC (Src homology 2 domain containing) transforming protein 1

(Aliases: P66shc)

Shc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
enzyme linked receptor protein signaling pathwayGO:00071671160.206
regulation of signal transductionGO:00099663180.198
intracellular signal transductionGO:00355563140.190
oxoacid metabolic processGO:00434362900.173
cellular amino acid metabolic processGO:00065201070.166
organic acid metabolic processGO:00060822920.156
cellular response to stressGO:00335542690.126
Worm
regulation of intracellular signal transductionGO:19025312180.125
signal transduction by phosphorylationGO:00230141440.122
response to mechanical stimulusGO:00096121340.119
amine metabolic processGO:0009308380.119
cellular response to oxygen containing compoundGO:19017013860.116
positive regulation of intracellular signal transductionGO:19025331380.112
regulation of cellular protein metabolic processGO:00322682670.111
negative regulation of protein metabolic processGO:00512481140.110
developmental process involved in reproductionGO:00030061590.110
regulation of protein metabolic processGO:00512462890.110
response to metal ionGO:00100382530.105
Worm
single organism reproductive processGO:00447022970.105
regulation of cellular amine metabolic processGO:003323880.105
peptidyl tyrosine phosphorylationGO:0018108720.104
cellular response to hormone stimulusGO:00328702470.103
reproductive system developmentGO:00614581280.103
cellular response to nitrogen compoundGO:19016992100.102
positive regulation of signal transductionGO:00099671750.100
carboxylic acid metabolic processGO:00197522890.099
positive regulation of mapk cascadeGO:0043410920.096
cellular response to insulin stimulusGO:0032869810.091
positive regulation of cell communicationGO:00106472710.091
regulation of protein phosphorylationGO:00019321830.091
cellular response to peptideGO:19016531330.086
positive regulation of signalingGO:00230562700.085
reproductive structure developmentGO:00486081280.083
reproductive processGO:00224143720.081
positive regulation of response to stimulusGO:00485842850.080
positive regulation of phosphorus metabolic processGO:00105622620.076
cellular ketone metabolic processGO:0042180510.076
olfactory learningGO:000835510.072
cellular amine metabolic processGO:0044106380.071
negative regulation of cellular metabolic processGO:00313242810.071
regulation of protein modification processGO:00313991940.071
cellular response to peptide hormone stimulusGO:00713751200.070
negative regulation of signalingGO:00230571570.070
negative regulation of molecular functionGO:00440921330.069
negative regulation of macromolecule metabolic processGO:00106052600.069
negative regulation of metabolic processGO:00098923310.068
response to insulinGO:00328681330.066
carbohydrate derivative metabolic processGO:19011353460.065
peptidyl amino acid modificationGO:00181931260.065
protein phosphorylationGO:00064683450.064
negative regulation of signal transductionGO:0009968830.062
regulation of cellular ketone metabolic processGO:0010565270.059
regulation of phosphorylationGO:00423252480.058
epithelium developmentGO:0060429960.058
regulation of cellular amino acid metabolic processGO:000652120.058
homeostatic processGO:00425923310.056
erbb signaling pathwayGO:0038127230.053
Mouse Fly
response to nutrientGO:00075842480.052
apoptotic processGO:00069153810.052
central nervous system developmentGO:00074173110.051
mapk cascadeGO:00001651400.050
rhythmic processGO:00485111560.050
response to peptideGO:19016522920.049
cell motilityGO:00488702020.049
response to ethanolGO:00454711620.047
protein heterooligomerizationGO:0051291890.047
olfactory behaviorGO:004204820.047
nucleobase containing small molecule metabolic processGO:00550863160.047
programmed cell deathGO:00125013920.047
positive regulation of phosphate metabolic processGO:00459372620.046
chemosensory behaviorGO:000763520.043
negative regulation of cell communicationGO:00106481580.042
cellular response to endogenous stimulusGO:00714953770.042
cellular response to organonitrogen compoundGO:00714171970.042
regulation of protein kinase activityGO:00458591050.041
regulation of cellular component organizationGO:00511283680.041
response to estrogenGO:00436272320.040
regulation of rna metabolic processGO:00512523910.039
Fly
nucleic acid templated transcriptionGO:00976593790.037
Fly
negative regulation of phosphorus metabolic processGO:0010563800.037
regulation of programmed cell deathGO:00430673410.036
response to extracellular stimulusGO:00099913800.036
ovulation cycleGO:0042698670.036
response to growth factorGO:00708481890.035
peptidyl tyrosine modificationGO:0018212720.035
transcription dna templatedGO:00063513770.035
Fly
cognitionGO:0050890920.035
sulfur compound metabolic processGO:0006790700.035
cellular response to abiotic stimulusGO:0071214850.034
cellular component assemblyGO:00226073600.033
reactive oxygen species metabolic processGO:0072593370.033
regulation of nucleic acid templated transcriptionGO:19035063800.032
Fly
positive regulation of macromolecule biosynthetic processGO:00105572470.032
heterocycle catabolic processGO:00467001670.032
regulation of phosphate metabolic processGO:00192203490.032
regulation of cell differentiationGO:00455953200.031
nitrogen compound transportGO:00717052290.031
response to inorganic substanceGO:00100353770.030
organophosphate biosynthetic processGO:00904071430.030
regulation of interleukin 6 productionGO:0032675120.030
nucleoside phosphate biosynthetic processGO:19012931020.029
cellular catabolic processGO:00442482950.029
nucleoside phosphate metabolic processGO:00067532830.029
gonad developmentGO:00084061040.029
positive regulation of developmental processGO:00510942830.029
regulation of phosphorus metabolic processGO:00511743490.029
multicellular organismal reproductive processGO:00486092330.029
glial cell differentiationGO:0010001650.028
nucleotide metabolic processGO:00091172790.028
regulation of cell morphogenesisGO:0022604770.028
regulation of cell proliferationGO:00421273590.028
regulation of kinase activityGO:00435491170.028
organophosphate metabolic processGO:00196373700.027
small gtpase mediated signal transductionGO:0007264360.027
ras protein signal transductionGO:0007265290.027
negative regulation of response to stimulusGO:00485851550.027
negative regulation of programmed cell deathGO:00430691830.027
negative regulation of gene expressionGO:00106291990.026
regulation of mapk cascadeGO:00434081160.026
response to oxidative stressGO:00069791860.026
response to cytokineGO:00340972150.026
positive regulation of transportGO:00510502450.026
organonitrogen compound biosynthetic processGO:19015661670.025
positive regulation of gene expressionGO:00106282440.025
positive regulation of cell proliferationGO:00082842490.025
carbohydrate derivative biosynthetic processGO:19011371240.025
astrocyte activationGO:004814340.025
blood circulationGO:00080151830.025
positive regulation of rna metabolic processGO:00512542030.025
tissue developmentGO:00098882520.025
response to nutrient levelsGO:00316673700.025
regulation of apoptotic processGO:00429813350.024
regulation of molecular functionGO:00650093980.024
regulation of transcription dna templatedGO:00063553740.024
Fly
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.023
interleukin 12 productionGO:003261530.023
interleukin 6 productionGO:0032635120.023
response to lipopolysaccharideGO:00324961910.023
defense responseGO:00069521940.023
Fly
negative regulation of apoptotic processGO:00430661810.023
development of primary sexual characteristicsGO:00451371070.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
multicellular organism reproductionGO:00325042330.023
chemical homeostasisGO:00488782920.022
tissue morphogenesisGO:0048729220.022
purine nucleotide metabolic processGO:00061632290.022
neuron projection developmentGO:00311752730.022
response to peptide hormoneGO:00434342780.022
sex differentiationGO:00075481130.022
response to woundingGO:00096112540.022
positive regulation of cellular protein metabolic processGO:00322701670.022
response to radiationGO:00093141370.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
regenerationGO:00310991630.021
protein oligomerizationGO:00512591910.021
positive regulation of nitrogen compound metabolic processGO:00511733340.021
response to transition metal nanoparticleGO:19902671220.021
inflammatory responseGO:00069541500.021
learning or memoryGO:0007611900.021
positive regulation of catalytic activityGO:00430851840.021
multicellular organism growthGO:003526410.021
nucleotide biosynthetic processGO:0009165980.020
brain developmentGO:00074202470.020
positive regulation of purine nucleotide metabolic processGO:1900544910.020
secretion by cellGO:00329402480.020
regulation of transferase activityGO:00513381230.020
response to vitaminGO:00332731310.019
positive regulation of protein phosphorylationGO:00019341350.019
regulation of rna biosynthetic processGO:20011413810.019
Fly
organic anion transportGO:00157111320.019
positive regulation of cellular amine metabolic processGO:003324030.019
positive regulation of smooth muscle cell proliferationGO:0048661510.019
regulation of reactive oxygen species metabolic processGO:2000377260.019
positive regulation of protein metabolic processGO:00512471780.019
rna metabolic processGO:00160704060.019
Fly
positive regulation of cellular biosynthetic processGO:00313282950.019
purine ribonucleotide metabolic processGO:00091502270.019
cell morphogenesisGO:00009021420.019
negative regulation of catalytic activityGO:00430861030.018
regulation of neuron deathGO:19012141150.018
metal ion homeostasisGO:00550651860.018
cellular response to acid chemicalGO:0071229750.018
positive regulation of multicellular organismal processGO:00512403870.018
ion homeostasisGO:00508012120.018
circulatory system processGO:00030131830.018
gliogenesisGO:0042063930.017
response to decreased oxygen levelsGO:00362932370.017
positive regulation of phosphorylationGO:00423271770.017
negative regulation of biosynthetic processGO:00098901680.017
organic substance catabolic processGO:19015753160.017
oxidation reduction processGO:00551143040.016
ribose phosphate metabolic processGO:00196932350.016
negative regulation of protein phosphorylationGO:0001933440.016
cellular response to cytokine stimulusGO:00713451270.016
ion transmembrane transportGO:00342203650.016
cytokine mediated signaling pathwayGO:0019221430.016
morphogenesis of an epitheliumGO:0002009200.016
cellular component biogenesisGO:00440853680.016
gland developmentGO:00487321550.016
single organism carbohydrate metabolic processGO:00447231180.016
protein complex assemblyGO:00064612630.016
cellular response to growth factor stimulusGO:00713631620.016
reproductionGO:00000032450.016
catabolic processGO:00090563510.016
single organism behaviorGO:00447081300.015
positive regulation of transcription dna templatedGO:00458931970.015
response to ketoneGO:19016541820.015
salivary gland developmentGO:000743130.015
macromolecular complex subunit organizationGO:00439333390.015
development of primary female sexual characteristicsGO:0046545560.015
macromolecular complex assemblyGO:00650032730.015
ribose phosphate biosynthetic processGO:0046390870.015
negative regulation of developmental processGO:00510931250.015
transmembrane transportGO:00550854120.015
cell activationGO:0001775970.015
negative regulation of mitotic cell cycle phase transitionGO:190199130.015
neuron projection morphogenesisGO:00488121220.015
regulation of anatomical structure sizeGO:00900661350.015
female sex differentiationGO:0046660590.015
cation homeostasisGO:00550801950.015
cellular response to alcoholGO:0097306870.015
axis specificationGO:000979840.015
liver developmentGO:0001889900.014
divalent inorganic cation homeostasisGO:00725071650.014
negative regulation of cell cycle g1 s phase transitionGO:190280720.014
single organism biosynthetic processGO:00447113420.014
regulation of organelle organizationGO:0033043800.014
negative regulation of cell cycle phase transitionGO:190198840.014
response to estradiolGO:00323551640.014
muscle cell proliferationGO:0033002840.014
ribonucleotide biosynthetic processGO:0009260850.013
cytokine biosynthetic processGO:004208930.013
purine nucleoside metabolic processGO:00422781690.013
ribonucleotide metabolic processGO:00092592310.013
organic cyclic compound catabolic processGO:19013611750.013
learningGO:0007612330.013
regulation of blood vessel sizeGO:0050880890.013
regulation of cellular localizationGO:00603412630.013
anion transportGO:00068201780.013
axon developmentGO:0061564960.013
muscle structure developmentGO:0061061870.013
placenta developmentGO:0001890220.013
negative regulation of phosphorylationGO:0042326570.013
multi organism reproductive processGO:00447032620.013
anatomical structure morphogenesisGO:00096532980.013
Mouse Fly
cellular response to mechanical stimulusGO:0071260480.013
actin filament organizationGO:0007015420.013
behaviorGO:00076102050.013
positive regulation of biosynthetic processGO:00098913190.013
response to acid chemicalGO:00011012220.013
cellular nitrogen compound catabolic processGO:00442701630.012
regulation of hormone levelsGO:00108171870.012
purine containing compound metabolic processGO:00725212530.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
response to corticosteroidGO:00319602350.012
female gonad developmentGO:0008585530.012
sexual reproductionGO:00199531480.012
negative regulation of cell differentiationGO:0045596990.012
peptide transportGO:0015833970.012
regulation of catabolic processGO:00098941130.012
cell cycle g1 s phase transitionGO:0044843130.012
regulation of multicellular organismal developmentGO:20000263760.012
lipid localizationGO:0010876620.012
translationGO:0006412350.012
positive regulation of kinase activityGO:0033674770.012
positive regulation of cell developmentGO:00107201760.012
cellular protein complex assemblyGO:0043623440.012
localization of cellGO:00516742020.012
single organism organelle organizationGO:19025891800.012
regulation of nucleotide metabolic processGO:00061401170.012
positive regulation of neurogenesisGO:00507691650.012
purine ribonucleotide biosynthetic processGO:0009152810.012
adult locomotory behaviorGO:000834440.012
negative regulation of multicellular organismal processGO:00512412030.012
positive regulation of protein modification processGO:00314011420.012
hepaticobiliary system developmentGO:0061008900.012
neuron differentiationGO:00301823680.012
regulation of anatomical structure morphogenesisGO:00226031410.012
positive regulation of neuron differentiationGO:00456661260.012
female pregnancyGO:00075651220.012
purine nucleotide biosynthetic processGO:0006164830.012
negative regulation of transferase activityGO:0051348290.012
hexose transportGO:0008645290.011
negative regulation of cell deathGO:00605482290.011
organelle organizationGO:00069962660.011
regulation of nervous system developmentGO:00519602640.011
cellular response to external stimulusGO:00714961180.011
growthGO:00400071650.011
regulation of receptor activityGO:0010469290.011
inorganic ion transmembrane transportGO:00986602290.011
regulation of catalytic activityGO:00507903040.011
head developmentGO:00603222470.011
response to biotic stimulusGO:00096072260.011
regulation of defense responseGO:0031347680.011
regulation of tumor necrosis factor productionGO:0032680130.011
macromolecule catabolic processGO:0009057580.011
positive regulation of rna biosynthetic processGO:19026801970.011
hair cycleGO:004263330.011
rna biosynthetic processGO:00327743800.011
Fly
protein complex subunit organizationGO:00718223020.011
neuron deathGO:00709971270.011
negative regulation of cellular amine metabolic processGO:003323930.011
regulation of cellular catabolic processGO:00313291010.011
carboxylic acid transportGO:00469421150.011
regulation of purine nucleotide metabolic processGO:19005421150.011
regulation of system processGO:00440572080.011
response to oxygen levelsGO:00704822650.011
nucleoside triphosphate catabolic processGO:00091431230.011
positive regulation of synaptic transmissionGO:0050806620.011
embryo developmentGO:0009790490.011
neuron neuron synaptic transmissionGO:0007270600.011
regulation of neurogenesisGO:00507672470.011
glycosyl compound metabolic processGO:19016571820.011
embryonic pattern specificationGO:000988010.010
positive regulation of cell differentiationGO:00455972170.010
positive regulation of nucleotide metabolic processGO:0045981910.010
regulation of smooth muscle cell proliferationGO:0048660750.010
negative regulation of phosphate metabolic processGO:0045936800.010
positive regulation of cellular component biogenesisGO:0044089550.010
molting cycleGO:004230330.010
negative regulation of cellular amino acid metabolic processGO:004576300.010
hemopoiesisGO:0030097340.010
chordate embryonic developmentGO:0043009180.010
negative regulation of protein kinase activityGO:0006469230.010
purine containing compound biosynthetic processGO:0072522850.010

Shc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
musculoskeletal system diseaseDOID:1700.016
cancerDOID:16200.012
organ system cancerDOID:005068600.012
disease of cellular proliferationDOID:1456600.012
central nervous system diseaseDOID:33100.012