Rattus norvegicus

5 known processes

Dio1

deiodinase, iodothyronine, type I

(Aliases: MGC93462,ITDI1,5DI,TXDI1)

Dio1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to monosaccharideGO:00342841590.430
response to carbohydrateGO:00097431830.343
transmembrane transportGO:00550854120.309
regulation of programmed cell deathGO:00430673410.308
response to peptideGO:19016522920.280
nitrogen compound transportGO:00717052290.272
carbohydrate metabolic processGO:00059751300.255
response to extracellular stimulusGO:00099913800.249
vesicle mediated transportGO:00161921810.208
growthGO:00400071650.199
response to nutrient levelsGO:00316673700.199
alpha amino acid metabolic processGO:1901605710.192
cellular ketone metabolic processGO:0042180510.189
cellular response to endogenous stimulusGO:00714953770.188
cellular amino acid metabolic processGO:00065201070.186
response to hexoseGO:00097461440.177
carboxylic acid metabolic processGO:00197522890.161
homeostatic processGO:00425923310.158
response to glucoseGO:00097491360.151
oxoacid metabolic processGO:00434362900.149
cation transportGO:00068123820.135
chemical homeostasisGO:00488782920.131
organophosphate metabolic processGO:00196373700.127
rhythmic processGO:00485111560.124
negative regulation of response to external stimulusGO:0032102370.121
hormone transportGO:00099141210.105
divalent inorganic cation transportGO:00725111340.104
cellular response to external stimulusGO:00714961180.098
response to transition metal nanoparticleGO:19902671220.095
apoptotic processGO:00069153810.095
regulation of molecular functionGO:00650093980.094
metal ion transportGO:00300012890.090
coenzyme metabolic processGO:0006732860.089
positive regulation of secretion by cellGO:19035321280.087
peptide secretionGO:0002790860.085
negative regulation of response to extracellular stimulusGO:003210570.085
negative regulation of response to foodGO:003209670.083
organic anion transportGO:00157111320.083
negative regulation of response to stimulusGO:00485851550.082
amine metabolic processGO:0009308380.080
cofactor metabolic processGO:0051186950.080
endocytosisGO:0006897840.079
glucagon secretionGO:007009150.078
cellular carbohydrate metabolic processGO:0044262720.077
cellular amine metabolic processGO:0044106380.076
anatomical structure morphogenesisGO:00096532980.075
secretionGO:00469033070.075
programmed cell deathGO:00125013920.074
cellular response to insulin stimulusGO:0032869810.073
ion transmembrane transportGO:00342203650.073
divalent metal ion transportGO:00708381320.073
regulation of vesicle mediated transportGO:0060627810.072
cell motilityGO:00488702020.072
negative regulation of growthGO:0045926370.071
amide transportGO:00428861050.070
cellular response to stressGO:00335542690.067
regulation of cellular ketone metabolic processGO:0010565270.066
behaviorGO:00076102050.066
response to toxic substanceGO:00096361330.066
lipid biosynthetic processGO:00086101280.066
reproductive processGO:00224143720.064
regulation of apoptotic processGO:00429813350.063
single organism carbohydrate metabolic processGO:00447231180.063
central nervous system developmentGO:00074173110.063
positive regulation of cellular component organizationGO:00511302000.062
regulation of cellular localizationGO:00603412630.062
carbohydrate derivative metabolic processGO:19011353460.061
generation of precursor metabolites and energyGO:0006091620.061
secretion by cellGO:00329402480.061
response to nutrientGO:00075842480.060
regulation of catalytic activityGO:00507903040.060
regulation of carbohydrate metabolic processGO:0006109410.060
sensory organ developmentGO:0007423740.059
regulation of peptide hormone secretionGO:0090276800.058
regulation of locomotionGO:00400121480.058
organic substance catabolic processGO:19015753160.057
regulation of peptide secretionGO:0002791820.057
small molecule biosynthetic processGO:00442831240.055
positive regulation of secretionGO:00510471400.055
regulation of blood pressureGO:0008217830.054
rna metabolic processGO:00160704060.053
agingGO:00075682410.053
multicellular organism growthGO:003526410.052
negative regulation of multicellular organismal processGO:00512412030.052
negative regulation of programmed cell deathGO:00430691830.051
regulation of cellular amino acid metabolic processGO:000652120.051
negative regulation of apoptotic processGO:00430661810.051
regulation of hormone levelsGO:00108171870.051
response to inorganic substanceGO:00100353770.051
signal releaseGO:00230611450.051
carbohydrate homeostasisGO:0033500750.050
learning or memoryGO:0007611900.050
response to vitaminGO:00332731310.050
regulation of peptide transportGO:0090087870.050
nucleobase containing small molecule metabolic processGO:00550863160.049
organic acid metabolic processGO:00060822920.049
energy derivation by oxidation of organic compoundsGO:0015980460.047
positive regulation of transportGO:00510502450.047
cellular homeostasisGO:00197252520.046
cellular response to vitamin dGO:0071305120.046
cognitionGO:0050890920.046
circadian rhythmGO:0007623880.045
head developmentGO:00603222470.044
calcium ion transportGO:00068161310.043
carbohydrate biosynthetic processGO:0016051420.043
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.042
cellular chemical homeostasisGO:00550822470.042
positive regulation of rna metabolic processGO:00512542030.042
regulation of developmental growthGO:0048638450.042
brain developmentGO:00074202470.041
response to vitamin dGO:0033280340.041
catabolic processGO:00090563510.040
regulation of cellular amine metabolic processGO:003323880.040
organelle organizationGO:00069962660.040
mrna transcriptionGO:000929920.039
lipid metabolic processGO:00066292830.039
positive regulation of multicellular organismal processGO:00512403870.039
locomotionGO:00400112370.038
peptide hormone secretionGO:0030072840.038
cellular amino acid catabolic processGO:0009063210.038
regulation of phosphorus metabolic processGO:00511743490.038
positive regulation of cell proliferationGO:00082842490.038
cell cycleGO:00070491010.038
cellular response to hexose stimulusGO:0071331650.038
single organism reproductive processGO:00447022970.037
maintenance of locationGO:0051235170.037
glucose homeostasisGO:0042593750.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.036
anion transportGO:00068201780.036
neurological system processGO:00508772190.036
cellular response to oxygen containing compoundGO:19017013860.036
single organism organelle organizationGO:19025891800.036
kidney developmentGO:0001822670.035
eye developmentGO:0001654500.035
forebrain developmentGO:0030900980.035
regulation of metal ion transportGO:00109591180.035
regulation of homeostatic processGO:00328441010.034
negative regulation of transportGO:00510511360.034
response to decreased oxygen levelsGO:00362932370.034
protein localizationGO:00081041910.034
gastric motilityGO:003548230.034
negative regulation of molecular functionGO:00440921330.034
hormone secretionGO:00468791150.034
single organism biosynthetic processGO:00447113420.034
exploration behaviorGO:003564010.034
sequestering of metal ionGO:005123890.034
single organism behaviorGO:00447081300.034
peptide transportGO:0015833970.034
oxidation reduction processGO:00551143040.033
response to mechanical stimulusGO:00096121340.033
ion homeostasisGO:00508012120.033
vitamin d receptor signaling pathwayGO:007056110.033
positive regulation of signalingGO:00230562700.032
defecationGO:003042110.032
positive regulation of macromolecule biosynthetic processGO:00105572470.032
regulation of cellular component organizationGO:00511283680.032
protein complex assemblyGO:00064612630.032
reproductionGO:00000032450.032
cellular response to peptide hormone stimulusGO:00713751200.031
regulation of response to stressGO:00801341260.031
synaptic transmissionGO:00072682350.031
organic hydroxy compound metabolic processGO:19016151150.031
regulation of cell projection organizationGO:00313441750.031
negative regulation of metabolic processGO:00098923310.030
single organism catabolic processGO:00447122830.030
response to woundingGO:00096112540.029
negative regulation of response to nutrient levelsGO:003210870.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
g protein coupled receptor signaling pathwayGO:00071862420.029
cellular lipid metabolic processGO:00442552080.029
camera type eye developmentGO:0043010480.029
regulation of pancreatic stellate cell proliferationGO:200022920.029
negative regulation of macromolecule metabolic processGO:00106052600.029
cellular component assemblyGO:00226073600.029
response to reactive oxygen speciesGO:00003021200.028
regulation of system processGO:00440572080.028
positive regulation of gene expressionGO:00106282440.028
cellular metal ion homeostasisGO:00068751720.028
negative regulation of cell deathGO:00605482290.028
membrane organizationGO:0061024940.028
cation homeostasisGO:00550801950.028
regulation of insulin secretionGO:0050796650.028
oligopeptide transportGO:000685740.028
macromolecular complex subunit organizationGO:00439333390.028
protein phosphorylationGO:00064683450.027
reproductive structure developmentGO:00486081280.027
insulin secretionGO:0030073690.027
regulation of cell proliferationGO:00421273590.027
cell morphogenesis involved in neuron differentiationGO:00486671060.027
positive regulation of cellular amine metabolic processGO:003324030.027
cellular ion homeostasisGO:00068731840.027
locomotory exploration behaviorGO:003564110.027
sequestering of calcium ionGO:005120880.027
positive regulation of rna biosynthetic processGO:19026801970.027
regulation of cell developmentGO:00602842630.027
regulation of organelle organizationGO:0033043800.026
positive regulation of peptide secretionGO:0002793520.026
regulation of intracellular signal transductionGO:19025312180.026
sex differentiationGO:00075481130.026
protein oligomerizationGO:00512591910.026
positive regulation of peptide hormone secretionGO:0090277500.026
negative regulation of cell proliferationGO:00082851190.026
response to peptide hormoneGO:00434342780.025
regulation of nervous system developmentGO:00519602640.025
regulation of cell cycleGO:0051726730.025
cell cell signalingGO:00072673350.025
endomembrane system organizationGO:0010256480.025
folic acid containing compound metabolic processGO:0006760100.025
reproductive system developmentGO:00614581280.025
regulation of hormone secretionGO:00468831060.025
negative regulation of secretionGO:0051048820.025
limbic system developmentGO:0021761380.025
response to electrical stimulusGO:0051602560.025
regulation of growthGO:00400081050.025
regulation of nucleic acid templated transcriptionGO:19035063800.025
striated muscle tissue developmentGO:0014706580.024
response to axon injuryGO:0048678590.024
lipid localizationGO:0010876620.024
positive regulation of developmental processGO:00510942830.024
cellular component movementGO:00069282480.024
intracellular transportGO:00469071850.024
regulation of endocytosisGO:0030100420.023
cell cycle processGO:0022402570.023
cellular response to peptideGO:19016531330.023
neuron projection developmentGO:00311752730.023
developmental process involved in reproductionGO:00030061590.023
positive regulation of nervous system developmentGO:00519621780.023
localization of cellGO:00516742020.022
phagocytosisGO:0006909170.022
response to oxygen levelsGO:00704822650.022
regulation of immune responseGO:0050776550.022
response to metal ionGO:00100382530.022
muscle tissue developmentGO:0060537580.022
response to estrogenGO:00436272320.022
single organism cellular localizationGO:19025801020.022
developmental growthGO:00485891000.022
macromolecular complex assemblyGO:00650032730.022
development of primary sexual characteristicsGO:00451371070.022
regulation of multicellular organismal developmentGO:20000263760.022
response to dexamethasoneGO:0071548490.022
inflammatory responseGO:00069541500.022
response to ethanolGO:00454711620.022
cellular modified amino acid metabolic processGO:0006575610.021
regulation of ion transportGO:00432692450.021
hexose metabolic processGO:0019318580.021
regulation of phosphate metabolic processGO:00192203490.021
tissue developmentGO:00098882520.021
organic acid transportGO:00158491160.021
regulation of immune system processGO:00026821230.021
leukocyte activationGO:0045321760.021
regulation of phagocytosisGO:0050764130.021
gland developmentGO:00487321550.020
eye morphogenesisGO:004859240.020
negative regulation of defense responseGO:0031348190.020
establishment of protein localizationGO:00451841410.020
blood circulationGO:00080151830.020
response to estradiolGO:00323551640.020
metal ion homeostasisGO:00550651860.020
carbohydrate derivative biosynthetic processGO:19011371240.020
cellular component biogenesisGO:00440853680.020
divalent inorganic cation homeostasisGO:00725071650.020
regulation of secretion by cellGO:19035302080.020
positive regulation of cell differentiationGO:00455972170.020
glutathione transportGO:003463520.020
positive regulation of response to stimulusGO:00485842850.020
acyl coa metabolic processGO:0006637280.019
positive regulation of homeostatic processGO:0032846490.019
regulation of protein metabolic processGO:00512462890.019
cell morphogenesis involved in differentiationGO:00009041190.019
defense response to other organismGO:0098542170.019
transcription dna templatedGO:00063513770.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
regulation of cell migrationGO:00303341280.019
indole containing compound metabolic processGO:0042430110.019
regulation of calcium ion transportGO:0051924770.019
positive regulation of neurogenesisGO:00507691650.019
response to corticosteroidGO:00319602350.019
rna biosynthetic processGO:00327743800.018
negative regulation of pancreatic stellate cell proliferationGO:200023010.018
cellular polysaccharide metabolic processGO:0044264230.018
regulation of transcription dna templatedGO:00063553740.018
regulation of gluconeogenesisGO:000611140.018
phospholipid metabolic processGO:0006644610.018
cell part morphogenesisGO:00329901230.018
dicarboxylic acid metabolic processGO:0043648420.018
regulation of serine type endopeptidase activityGO:190000310.018
cellular response to nitrogen compoundGO:19016992100.018
anatomical structure homeostasisGO:0060249290.018
cellular cation homeostasisGO:00300031800.018
female sex differentiationGO:0046660590.018
axis specificationGO:000979840.018
response to glucocorticoidGO:00513842230.018
regulation of transmembrane transportGO:00347621220.018
ensheathment of neuronsGO:0007272400.017
response to external biotic stimulusGO:00432072210.017
cellular response to glucose stimulusGO:0071333650.017
negative regulation of catalytic activityGO:00430861030.017
organonitrogen compound biosynthetic processGO:19015661670.017
negative regulation of calcium ion importGO:009028120.017
response to hypoxiaGO:00016662310.017
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
catecholamine secretionGO:0050432330.017
regulation of cell motilityGO:20001451310.017
negative regulation of ion transportGO:0043271510.017
transmission of nerve impulseGO:0019226420.017
monosaccharide metabolic processGO:0005996610.017
glucose metabolic processGO:0006006520.017
positive regulation of insulin secretionGO:0032024360.017
response to cocaineGO:0042220390.017
cellular response to vitamin eGO:007130630.017
small gtpase mediated signal transductionGO:0007264360.017
dicarboxylic acid transportGO:0006835340.017
positive regulation of transcription dna templatedGO:00458931970.017
carboxylic acid transportGO:00469421150.017
regulation of cell growthGO:0001558850.017
response to activityGO:0014823730.016
multi organism reproductive processGO:00447032620.016
multicellular organismal signalingGO:0035637440.016
cellular response to nutrient levelsGO:0031669600.016
negative regulation of luteinizing hormone secretionGO:003368540.016
drug transmembrane transportGO:0006855130.016
positive regulation of synaptic transmissionGO:0050806620.016
nucleic acid templated transcriptionGO:00976593790.016
cell activationGO:0001775970.016
monocarboxylic acid metabolic processGO:00327871520.016
cell morphogenesisGO:00009021420.016
alpha amino acid catabolic processGO:1901606200.016
regulation of hydrolase activityGO:00513361430.016
cellular catabolic processGO:00442482950.016
protein complex biogenesisGO:00702712630.016
sodium ion transportGO:0006814820.016
purine containing compound metabolic processGO:00725212530.016
cellular response to monosaccharide stimulusGO:0071326670.015
reactive nitrogen species metabolic processGO:200105710.015
regulation of lipid metabolic processGO:0019216680.015
positive regulation of intracellular signal transductionGO:19025331380.015
regulation of defense responseGO:0031347680.015
regulation of glucagon secretionGO:007009250.015
heart morphogenesisGO:000300730.015
reactive oxygen species biosynthetic processGO:190340980.015
ovulation cycleGO:0042698670.015
muscle structure developmentGO:0061061870.015
macromolecule localizationGO:00330362520.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
tetrahydrofolate metabolic processGO:004665390.015
protein complex subunit organizationGO:00718223020.015
cellular response to extracellular stimulusGO:0031668730.015
cell projection organizationGO:00300303020.015
digestive tract developmentGO:0048565390.015
fatty acid metabolic processGO:0006631990.015
regulation of synaptic plasticityGO:0048167700.015
regulation of neuron projection developmentGO:00109751610.015
skeletal muscle tissue developmentGO:0007519310.015
negative regulation of cellular metabolic processGO:00313242810.015
thioester metabolic processGO:0035383280.014
regulation of membrane potentialGO:00423911100.014
positive regulation of cellular biosynthetic processGO:00313282950.014
associative learningGO:0008306190.014
ras protein signal transductionGO:0007265290.014
regulation of response to external stimulusGO:00321011060.014
regulation of cellular catabolic processGO:00313291010.014
regulation of defecationGO:200029210.014
intracellular receptor signaling pathwayGO:0030522350.014
nucleoside phosphate metabolic processGO:00067532830.014
lipid storageGO:001991510.014
retina development in camera type eyeGO:0060041270.014
ribose phosphate metabolic processGO:00196932350.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
lipid modificationGO:0030258520.014
digestive system developmentGO:0055123410.014
myeloid leukocyte activationGO:0002274360.014
development of primary female sexual characteristicsGO:0046545560.014
multi multicellular organism processGO:00447061380.014
organophosphate biosynthetic processGO:00904071430.014
neuronal action potentialGO:0019228350.014
negative regulation of cellular protein metabolic processGO:00322691060.014
inorganic ion transmembrane transportGO:00986602290.014
regulation of neurogenesisGO:00507672470.014
intracellular signal transductionGO:00355563140.014
neuron differentiationGO:00301823680.014
cellular calcium ion homeostasisGO:00068741600.013
organelle localizationGO:0051640550.013
purine ribonucleotide metabolic processGO:00091502270.013
cellular response to carbohydrate stimulusGO:0071322720.013
regulation of generation of precursor metabolites and energyGO:0043467180.013
proteolysisGO:00065081750.013
amine transportGO:0015837570.013
cell growthGO:00160491040.013
renal system developmentGO:0072001670.013
multicellular organismal homeostasisGO:0048871490.013
vesicle localizationGO:0051648330.013
phenol containing compound metabolic processGO:0018958300.013
female pregnancyGO:00075651220.013
monosaccharide transportGO:0015749310.013
response to mineralocorticoidGO:0051385490.013
cellular protein localizationGO:00346131220.013
response to cytokineGO:00340972150.013
adult behaviorGO:0030534160.013
multicellular organism reproductionGO:00325042330.013
cellular glucose homeostasisGO:0001678660.013
positive regulation of biosynthetic processGO:00098913190.013
single organism intracellular transportGO:19025821660.013
regulation of cell differentiationGO:00455953200.013
response to chromateGO:004668730.013
excretionGO:0007588240.012
aromatic amino acid family catabolic processGO:000907470.012
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.012
gonad developmentGO:00084061040.012
regulation of neuron deathGO:19012141150.012
regulation of cellular carbohydrate metabolic processGO:0010675390.012
nucleotide metabolic processGO:00091172790.012
neuron developmentGO:00486662860.012
protein tetramerizationGO:0051262380.012
sphingolipid biosynthetic processGO:003014840.012
cation transmembrane transportGO:00986552630.012
cellular response to steroid hormone stimulusGO:0071383930.012
muscle cell proliferationGO:0033002840.012
nucleoside metabolic processGO:00091161790.012
response to corticosteroneGO:0051412400.012
cellular response to mechanical stimulusGO:0071260480.012
positive regulation of hormone secretionGO:0046887650.012
response to vitamin kGO:003257140.012
inner medullary collecting duct developmentGO:007206110.012
response to potassium ionGO:003586490.012
negative regulation of acute inflammatory responseGO:000267440.012
olfactory learningGO:000835510.012
olfactory behaviorGO:004204820.012
carboxylic acid biosynthetic processGO:0046394830.012
exogenous drug catabolic processGO:004273810.012
nucleotide biosynthetic processGO:0009165980.012
maternal process involved in female pregnancyGO:0060135380.012
defense response to gram positive bacteriumGO:005083020.012
nucleoside phosphate biosynthetic processGO:19012931020.012
phospholipid biosynthetic processGO:0008654290.012
cellular response to ketoneGO:1901655510.012
axonogenesisGO:0007409710.012
carboxylic acid catabolic processGO:0046395490.012
positive regulation of vasodilationGO:0045909290.012
positive regulation of neuron projection developmentGO:0010976990.012
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.012
calcium ion importGO:0070509220.012
purine nucleotide metabolic processGO:00061632290.011
circulatory system processGO:00030131830.011
cellular response to organonitrogen compoundGO:00714171970.011
regulation of intracellular transportGO:0032386650.011
cytoplasmic transportGO:00164821150.011
sodium independent organic anion transportGO:004325220.011
regulation of corticotropin secretionGO:005145970.011
4 nitrophenol metabolic processGO:001896010.011
defense response to gram negative bacteriumGO:005082930.011
insulin like growth factor receptor signaling pathwayGO:004800930.011
cytoskeleton organizationGO:00070101110.011
response to zinc ionGO:0010043390.011
response to acid chemicalGO:00011012220.011
muscle organ developmentGO:0007517500.011
antibiotic transportGO:004289120.011
protein importGO:0017038370.011
sulfur compound metabolic processGO:0006790700.011
ribonucleoside metabolic processGO:00091191740.011
cellular macromolecular complex assemblyGO:0034622580.011
sensory perception of bitter tasteGO:005091340.011
regulation of cellular component movementGO:00512701500.011
toxin transportGO:190199830.011
aspartate family amino acid metabolic processGO:0009066100.011
cellular component morphogenesisGO:00329891550.011
organonitrogen compound catabolic processGO:19015651790.011
cytokine productionGO:0001816610.011
gluconeogenesisGO:0006094150.011
negative regulation of sequestering of calcium ionGO:0051283250.011
protein maturationGO:0051604680.011
response to antibioticGO:0046677390.011
regulation of synaptic transmissionGO:00508041410.011
monovalent inorganic cation transportGO:00156721720.011
negative regulation of signalingGO:00230571570.011
gastrulationGO:000736920.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
pancreatic stellate cell proliferationGO:007234320.011
liver developmentGO:0001889900.010
cell projection morphogenesisGO:00488581230.010
positive regulation of cytoplasmic transportGO:1903651320.010
regulation of amine transportGO:0051952540.010
peptidyl tyrosine phosphorylationGO:0018108720.010
positive regulation of mast cell activationGO:003300540.010
hexose biosynthetic processGO:0019319150.010
wound healingGO:00420601220.010
kidney epithelium developmentGO:0072073190.010
response to foodGO:0032094270.010

Dio1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
disease of metabolismDOID:001466700.025
vascular diseaseDOID:17800.025
cardiovascular system diseaseDOID:128700.025
central nervous system diseaseDOID:33100.017
inherited metabolic disorderDOID:65500.015
acquired metabolic diseaseDOID:006015800.012
long qt syndromeDOID:284300.012