Rattus norvegicus

11 known processes

Dio3

deiodinase, iodothyronine, type III

(Aliases: DIOIII,5DIII)

Dio3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.391
locomotionGO:00400112370.275
g protein coupled receptor signaling pathwayGO:00071862420.236
nitrogen compound transportGO:00717052290.209
cellular response to endogenous stimulusGO:00714953770.184
learning or memoryGO:0007611900.179
protein complex biogenesisGO:00702712630.171
protein complex subunit organizationGO:00718223020.162
cellular component biogenesisGO:00440853680.148
anion transportGO:00068201780.146
cellular component movementGO:00069282480.146
macromolecular complex subunit organizationGO:00439333390.144
protein complex assemblyGO:00064612630.142
hormone transportGO:00099141210.137
cell projection morphogenesisGO:00488581230.133
regulation of cellular component movementGO:00512701500.133
inorganic cation transmembrane transportGO:00986622020.124
cellular component assemblyGO:00226073600.122
regulation of catalytic activityGO:00507903040.112
cell part morphogenesisGO:00329901230.110
cation transportGO:00068123820.110
protein phosphorylationGO:00064683450.107
regulation of molecular functionGO:00650093980.106
cation transmembrane transportGO:00986552630.105
protein oligomerizationGO:00512591910.101
multi multicellular organism processGO:00447061380.095
cellular component morphogenesisGO:00329891550.095
ion transmembrane transportGO:00342203650.095
reproductive processGO:00224143720.094
regulation of phosphorus metabolic processGO:00511743490.093
positive regulation of ion transportGO:0043270940.092
homeostatic processGO:00425923310.092
protein heterooligomerizationGO:0051291890.091
negative regulation of cell deathGO:00605482290.091
epithelial cell differentiationGO:0030855710.089
localization of cellGO:00516742020.088
female pregnancyGO:00075651220.088
cell projection organizationGO:00300303020.087
macromolecular complex assemblyGO:00650032730.086
regulation of cell motilityGO:20001451310.082
regulation of cell proliferationGO:00421273590.082
organic acid transportGO:00158491160.080
regulation of blood pressureGO:0008217830.079
neuron projection morphogenesisGO:00488121220.077
neuron projection developmentGO:00311752730.077
carboxylic acid transportGO:00469421150.075
cellular amino acid metabolic processGO:00065201070.074
negative regulation of cellular biosynthetic processGO:00313271610.073
tissue developmentGO:00098882520.073
secretionGO:00469033070.073
regulation of phosphate metabolic processGO:00192203490.072
response to estradiolGO:00323551640.069
cardiovascular system developmentGO:00723581340.068
regulation of phosphorylationGO:00423252480.068
positive regulation of response to stimulusGO:00485842850.068
regulation of hormone levelsGO:00108171870.067
regulation of multicellular organismal developmentGO:20000263760.067
chemical homeostasisGO:00488782920.066
positive regulation of cell proliferationGO:00082842490.066
response to peptide hormoneGO:00434342780.065
cell morphogenesisGO:00009021420.065
rna metabolic processGO:00160704060.064
regulation of cellular component organizationGO:00511283680.063
multi organism reproductive processGO:00447032620.063
reproductionGO:00000032450.061
regulation of cell differentiationGO:00455953200.060
regulation of locomotionGO:00400121480.060
neuron differentiationGO:00301823680.060
positive regulation of cellular biosynthetic processGO:00313282950.059
multicellular organism reproductionGO:00325042330.057
amide transportGO:00428861050.057
neuron developmentGO:00486662860.057
negative regulation of biosynthetic processGO:00098901680.055
potassium ion transportGO:0006813970.054
regulation of rna metabolic processGO:00512523910.054
organic acid metabolic processGO:00060822920.054
negative regulation of multicellular organismal processGO:00512412030.053
oxoacid metabolic processGO:00434362900.053
anatomical structure morphogenesisGO:00096532980.052
blood circulationGO:00080151830.052
organophosphate metabolic processGO:00196373700.052
positive regulation of neurogenesisGO:00507691650.051
cell morphogenesis involved in neuron differentiationGO:00486671060.051
negative regulation of macromolecule metabolic processGO:00106052600.048
cell migrationGO:00164771970.047
regulation of transcription from rna polymerase ii promoterGO:00063572340.047
positive regulation of protein modification processGO:00314011420.047
urinary bladder smooth muscle contractionGO:001483240.047
behaviorGO:00076102050.047
negative regulation of macromolecule biosynthetic processGO:00105581480.047
regulation of neurogenesisGO:00507672470.046
amino acid transportGO:0006865700.045
negative regulation of cell communicationGO:00106481580.044
secretion by cellGO:00329402480.044
positive regulation of molecular functionGO:00440932300.043
cellular response to hormone stimulusGO:00328702470.043
cell morphogenesis involved in differentiationGO:00009041190.043
sexual reproductionGO:00199531480.043
response to extracellular stimulusGO:00099913800.043
negative regulation of signalingGO:00230571570.042
positive regulation of phosphorylationGO:00423271770.042
cyclic purine nucleotide metabolic processGO:0052652620.042
response to nutrient levelsGO:00316673700.041
regulation of nervous system developmentGO:00519602640.041
organic anion transportGO:00157111320.041
response to alkaloidGO:00432791320.040
negative regulation of cellular metabolic processGO:00313242810.040
cellular amine metabolic processGO:0044106380.040
cell motilityGO:00488702020.040
positive regulation of phosphate metabolic processGO:00459372620.040
regulation of signal transductionGO:00099663180.039
positive regulation of protein phosphorylationGO:00019341350.038
positive regulation of multicellular organismal processGO:00512403870.038
choline transportGO:001587140.038
response to growth factorGO:00708481890.038
neurological system processGO:00508772190.037
multicellular organismal reproductive processGO:00486092330.037
regulation of rna biosynthetic processGO:20011413810.037
carboxylic acid metabolic processGO:00197522890.037
synaptic transmissionGO:00072682350.037
sensory perceptionGO:00076001010.036
hormone secretionGO:00468791150.036
peptide hormone secretionGO:0030072840.036
response to corticosteroidGO:00319602350.036
single organism biosynthetic processGO:00447113420.036
purine ribonucleotide metabolic processGO:00091502270.036
regulation of secretion by cellGO:19035302080.036
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
sleepGO:0030431300.035
gastrulationGO:000736920.035
positive regulation of signal transductionGO:00099671750.035
negative regulation of gene expressionGO:00106291990.034
regulation of nucleic acid templated transcriptionGO:19035063800.034
negative regulation of secretion by cellGO:1903531720.034
regulation of mapk cascadeGO:00434081160.034
brain developmentGO:00074202470.034
carbohydrate derivative biosynthetic processGO:19011371240.034
programmed cell deathGO:00125013920.033
monocarboxylic acid transportGO:0015718520.033
organonitrogen compound biosynthetic processGO:19015661670.033
calcium ion transportGO:00068161310.033
actin filament based processGO:0030029860.033
regulation of blood vessel sizeGO:0050880890.033
divalent inorganic cation transportGO:00725111340.033
purine nucleotide biosynthetic processGO:0006164830.033
chemotaxisGO:0006935660.032
metal ion transportGO:00300012890.032
regulation of protein phosphorylationGO:00019321830.032
negative regulation of developmental processGO:00510931250.032
single organism behaviorGO:00447081300.032
amine metabolic processGO:0009308380.032
rna biosynthetic processGO:00327743800.032
response to dexamethasoneGO:0071548490.031
amino acid transmembrane transportGO:0003333330.031
regulation of protein metabolic processGO:00512462890.031
cellular chemical homeostasisGO:00550822470.030
response to peptideGO:19016522920.030
regulation of reactive oxygen species metabolic processGO:2000377260.030
cytosolic calcium ion homeostasisGO:00514801400.030
positive regulation of phosphorus metabolic processGO:00105622620.030
cellular response to oxygen containing compoundGO:19017013860.030
cyclic nucleotide biosynthetic processGO:0009190630.029
regulation of cellular protein metabolic processGO:00322682670.029
peptide secretionGO:0002790860.029
signal transduction by phosphorylationGO:00230141440.029
catecholamine transportGO:0051937370.029
cellular lipid metabolic processGO:00442552080.029
single organism reproductive processGO:00447022970.029
central nervous system developmentGO:00074173110.029
nucleoside phosphate biosynthetic processGO:19012931020.029
vascular process in circulatory systemGO:0003018960.028
positive regulation of cellular protein metabolic processGO:00322701670.028
negative regulation of response to stimulusGO:00485851550.028
muscle structure developmentGO:0061061870.028
negative regulation of nitrogen compound metabolic processGO:00511721610.028
nucleobase containing small molecule metabolic processGO:00550863160.028
cellular homeostasisGO:00197252520.028
regulation of body fluid levelsGO:0050878900.028
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.028
metal ion homeostasisGO:00550651860.028
peptide transportGO:0015833970.027
sensory perception of painGO:0019233730.027
organic hydroxy compound transportGO:0015850770.027
ribonucleotide biosynthetic processGO:0009260850.027
regulation of cell migrationGO:00303341280.027
phasic smooth muscle contractionGO:001482130.027
regulation of programmed cell deathGO:00430673410.027
regulation of transcription dna templatedGO:00063553740.027
receptor metabolic processGO:0043112180.026
regulation of cellular amine metabolic processGO:003323880.026
cellular response to external stimulusGO:00714961180.026
regulation of anatomical structure sizeGO:00900661350.026
regulation of membrane potentialGO:00423911100.026
nucleoside phosphate metabolic processGO:00067532830.026
positive regulation of cytosolic calcium ion concentrationGO:00072041220.026
positive regulation of cellular amine metabolic processGO:003324030.026
head developmentGO:00603222470.026
catabolic processGO:00090563510.026
negative regulation of blood pressureGO:0045776290.025
positive regulation of dopamine secretionGO:003360380.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
circulatory system processGO:00030131830.025
ribose phosphate metabolic processGO:00196932350.025
response to nutrientGO:00075842480.025
regulation of ion transportGO:00432692450.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.025
nucleotide metabolic processGO:00091172790.025
apoptotic processGO:00069153810.024
regulation of protein modification processGO:00313991940.024
cellular divalent inorganic cation homeostasisGO:00725031620.024
epithelium developmentGO:0060429960.024
single organism intracellular transportGO:19025821660.024
cellular metal ion homeostasisGO:00068751720.024
regulation of camp metabolic processGO:0030814430.024
response to ammonium ionGO:0060359710.024
mesoderm developmentGO:000749820.024
regulation of saliva secretionGO:004687730.024
negative regulation of programmed cell deathGO:00430691830.024
calcium ion homeostasisGO:00550741620.023
response to cytokineGO:00340972150.023
cellular response to nitrogen compoundGO:19016992100.023
negative regulation of metabolic processGO:00098923310.023
axon developmentGO:0061564960.022
regulation of cellular ketone metabolic processGO:0010565270.022
response to lipopolysaccharideGO:00324961910.022
positive regulation of biosynthetic processGO:00098913190.022
actin cytoskeleton organizationGO:0030036730.022
regulation of system processGO:00440572080.022
divalent inorganic cation homeostasisGO:00725071650.022
negative regulation of molecular functionGO:00440921330.022
cell cell signalingGO:00072673350.022
regulation of cellular localizationGO:00603412630.022
regulation of peptide transportGO:0090087870.022
heart morphogenesisGO:000300730.021
positive regulation of signalingGO:00230562700.021
renal system processGO:0003014400.021
gland developmentGO:00487321550.021
monovalent inorganic cation transportGO:00156721720.021
cardiac chamber developmentGO:000320510.021
circadian sleep wake cycle sleepGO:0050802210.021
purine containing compound biosynthetic processGO:0072522850.021
purine containing compound metabolic processGO:00725212530.021
regulation of kinase activityGO:00435491170.021
anterior posterior pattern specificationGO:000995210.021
regulation of camp biosynthetic processGO:0030817380.021
ribonucleotide metabolic processGO:00092592310.020
monoamine transportGO:0015844430.020
rhythmic processGO:00485111560.020
positive regulation of cell developmentGO:00107201760.020
detection of visible lightGO:000958430.020
muscle system processGO:00030121150.020
response to nicotineGO:0035094510.020
regulation of apoptotic processGO:00429813350.020
negative regulation of hormone secretionGO:0046888460.020
cellular response to alcoholGO:0097306870.020
positive regulation of catalytic activityGO:00430851840.019
regulation of cellular amino acid metabolic processGO:000652120.019
epithelial cell proliferationGO:0050673540.019
cellular response to growth factor stimulusGO:00713631620.019
positive regulation of cell communicationGO:00106472710.019
purine ribonucleotide biosynthetic processGO:0009152810.019
cellular calcium ion homeostasisGO:00068741600.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
anatomical structure formation involved in morphogenesisGO:0048646830.019
nucleotide biosynthetic processGO:0009165980.019
axonogenesisGO:0007409710.019
response to other organismGO:00517072200.019
regulation of transporter activityGO:0032409500.019
heart contractionGO:0060047570.019
response to ketoneGO:19016541820.019
ribose phosphate biosynthetic processGO:0046390870.019
regulation of cell projection organizationGO:00313441750.018
spermatogenesisGO:0007283990.018
regulation of peptide hormone secretionGO:0090276800.018
response to glucocorticoidGO:00513842230.018
reactive oxygen species metabolic processGO:0072593370.018
secretion by tissueGO:0032941370.018
circadian sleep wake cycleGO:0042745230.018
cellular carbohydrate metabolic processGO:0044262720.018
pancreatic a cell differentiationGO:000331010.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
arginine transportGO:001580950.018
regulation of cell developmentGO:00602842630.018
response to hexoseGO:00097461440.018
regulation of peptide secretionGO:0002791820.018
cellular cation homeostasisGO:00300031800.018
circulatory system developmentGO:00723591340.018
divalent metal ion transportGO:00708381320.018
negative regulation of cell differentiationGO:0045596990.018
limb morphogenesisGO:003510840.017
glucose homeostasisGO:0042593750.017
regulation of vasoconstrictionGO:0019229440.017
anion transmembrane transportGO:0098656770.017
negative regulation of transcription dna templatedGO:00458921160.017
intracellular signal transductionGO:00355563140.017
response to decreased oxygen levelsGO:00362932370.017
camp biosynthetic processGO:0006171470.017
gamete generationGO:00072761240.017
regulation of purine nucleotide biosynthetic processGO:1900371460.017
regulation of secretionGO:00510462240.017
regulation of vesicle mediated transportGO:0060627810.017
muscle cell proliferationGO:0033002840.017
neurotransmitter uptakeGO:000150430.016
carbohydrate homeostasisGO:0033500750.016
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.016
multicellular organismal signalingGO:0035637440.016
protein homooligomerizationGO:0051260910.016
positive regulation of protein metabolic processGO:00512471780.016
embryonic appendage morphogenesisGO:003511340.016
negative regulation of secretionGO:0051048820.016
regulation of angiogenesisGO:0045765390.016
female gonad developmentGO:0008585530.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.016
positive regulation of amine transportGO:0051954260.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
regulation of cyclic nucleotide metabolic processGO:0030799510.016
negative regulation of rna biosynthetic processGO:19026791180.016
cardiac ventricle developmentGO:000323110.016
response to woundingGO:00096112540.016
response to mineralocorticoidGO:0051385490.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.015
positive regulation of gene expressionGO:00106282440.015
positive regulation of long term synaptic potentiationGO:190027340.015
phospholipid metabolic processGO:0006644610.015
regulation of amine transportGO:0051952540.015
regulation of insulin secretionGO:0050796650.015
regulation of catecholamine secretionGO:0050433320.015
transcription from rna polymerase ii promoterGO:00063662520.015
response to activityGO:0014823730.014
response to purine containing compoundGO:00140741260.014
regulation of response to external stimulusGO:00321011060.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
regulation of nucleotide metabolic processGO:00061401170.014
cellular response to ammonium ionGO:0071242170.014
regulation of neuron differentiationGO:00456642080.014
regulation of muscle system processGO:0090257790.014
positive regulation of intracellular signal transductionGO:19025331380.014
regulation of cell growthGO:0001558850.014
regulation of blood circulationGO:19035221100.014
dendrite morphogenesisGO:0048813430.014
positive regulation of camp biosynthetic processGO:0030819280.014
positive regulation of purine nucleotide biosynthetic processGO:1900373360.014
digestive system processGO:0022600240.014
circadian rhythmGO:0007623880.014
proteolysisGO:00065081750.014
response to morphineGO:0043278270.014
protein catabolic processGO:0030163300.014
organonitrogen compound catabolic processGO:19015651790.014
regulation of defense responseGO:0031347680.014
cell type specific apoptotic processGO:00972851340.014
cellular catabolic processGO:00442482950.014
action potentialGO:0001508540.013
negative regulation of apoptotic processGO:00430661810.013
alpha amino acid metabolic processGO:1901605710.013
neuromuscular processGO:005090520.013
negative regulation of catalytic activityGO:00430861030.013
positive regulation of developmental processGO:00510942830.013
nucleic acid templated transcriptionGO:00976593790.013
negative regulation of transportGO:00510511360.013
organophosphate biosynthetic processGO:00904071430.013
negative regulation of purine nucleotide metabolic processGO:1900543230.013
regulation of homeostatic processGO:00328441010.013
cytoskeleton organizationGO:00070101110.013
striated muscle contractionGO:0006941440.013
lipid biosynthetic processGO:00086101280.013
visual perceptionGO:000760130.013
response to hyperoxiaGO:0055093450.013
regulation of protein kinase activityGO:00458591050.013
response to monosaccharideGO:00342841590.013
potassium ion transmembrane transportGO:0071805710.013
alcohol metabolic processGO:0006066770.013
positive regulation of cell differentiationGO:00455972170.013
regulation of response to woundingGO:1903034690.013
neural crest cell differentiationGO:001403320.013
negative regulation of signal transductionGO:0009968830.013
insulin secretionGO:0030073690.013
micturitionGO:006007340.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
acute inflammatory responseGO:0002526580.013
regulation of purine nucleotide metabolic processGO:19005421150.013
reproductive system developmentGO:00614581280.013
positive regulation of secretionGO:00510471400.013
bmp signaling pathwayGO:003050940.013
regulation of neuron projection developmentGO:00109751610.013
response to estrogenGO:00436272320.013
cellular response to drugGO:0035690300.013
cellular ketone metabolic processGO:0042180510.013
regulation of behaviorGO:0050795610.012
dna metabolic processGO:0006259960.012
circadian sleep wake cycle processGO:0022410210.012
negative regulation of nervous system developmentGO:0051961790.012
response to insulinGO:00328681330.012
grooming behaviorGO:000762540.012
phototransduction visible lightGO:000760320.012
lipid metabolic processGO:00066292830.012
motor neuron axon guidanceGO:000804510.012
dendrite developmentGO:0016358720.012
regulation of smooth muscle cell proliferationGO:0048660750.012
actin mediated cell contractionGO:0070252120.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.012
cellular amide metabolic processGO:0043603440.012
smooth muscle contractionGO:0006939370.012
regulation of cellular component biogenesisGO:0044087860.012
response to biotic stimulusGO:00096072260.012
purine nucleotide metabolic processGO:00061632290.012
inflammatory responseGO:00069541500.012
salivary gland developmentGO:000743130.012
cyclic nucleotide metabolic processGO:0009187800.012
camp metabolic processGO:0046058630.012
cellular response to organonitrogen compoundGO:00714171970.012
regulation of transmembrane transportGO:00347621220.012
cellular response to steroid hormone stimulusGO:0071383930.012
response to metal ionGO:00100382530.012
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.012
forebrain developmentGO:0030900980.012
regulation of epithelial cell proliferationGO:0050678490.012
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.012
ameboidal type cell migrationGO:0001667260.012
negative regulation of cell developmentGO:0010721820.012
l glutamate importGO:005193820.012
digestionGO:0007586260.012
negative regulation of circadian rhythmGO:004275450.011
regulation of synaptic transmissionGO:00508041410.011
actin filament organizationGO:0007015420.011
response to glucoseGO:00097491360.011
response to oxygen levelsGO:00704822650.011
mapk cascadeGO:00001651400.011
muscle contractionGO:0006936880.011
organic substance catabolic processGO:19015753160.011
positive regulation of nervous system developmentGO:00519621780.011
saliva secretionGO:004654130.011
male gamete generationGO:0048232990.011
regulation of transferase activityGO:00513381230.011
muscle cell apoptotic processGO:0010657300.011
positive regulation of rna biosynthetic processGO:19026801970.011
embryonic limb morphogenesisGO:003032640.011
cellular potassium ion transportGO:0071804720.011
regulation of dopamine secretionGO:0014059150.011
dephosphorylationGO:0016311980.011
regulation of ion transmembrane transportGO:00347651210.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
regulation of systemic arterial blood pressureGO:0003073300.011
inorganic ion transmembrane transportGO:00986602290.011
urogenital system developmentGO:0001655780.011
cellular response to dexamethasone stimulusGO:0071549360.011
embryonic pattern specificationGO:000988010.011
organelle organizationGO:00069962660.011
feeding behaviorGO:0007631530.011
dicarboxylic acid transportGO:0006835340.011
transcription dna templatedGO:00063513770.011
positive regulation of cell migrationGO:0030335960.011
response to cocaineGO:0042220390.011
carbohydrate derivative metabolic processGO:19011353460.011
cellular response to alkaloidGO:0071312250.011
regulation of heart contractionGO:0008016480.011
response to hypoxiaGO:00016662310.011
sensory perception of light stimulusGO:005095330.011
positive regulation of peptide hormone secretionGO:0090277500.011
development of primary sexual characteristicsGO:00451371070.010
embryo developmentGO:0009790490.010
agingGO:00075682410.010
axis specificationGO:000979840.010
response to increased oxygen levelsGO:0036296450.010
urinary tract smooth muscle contractionGO:001484840.010
regulation of canonical wnt signaling pathwayGO:006082840.010
development of primary female sexual characteristicsGO:0046545560.010
regulation of hormone secretionGO:00468831060.010
regulation of hydrolase activityGO:00513361430.010
coronary vasculature morphogenesisGO:006097730.010
positive regulation of transportGO:00510502450.010
negative regulation of protein metabolic processGO:00512481140.010

Dio3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
sensory system diseaseDOID:005015500.017
eye and adnexa diseaseDOID:149200.015
eye diseaseDOID:561400.015