Rattus norvegicus

23 known processes

Mthfd1

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

Mthfd1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.190
Yeast
alpha amino acid metabolic processGO:1901605710.121
Yeast
single organism biosynthetic processGO:00447113420.118
Yeast
oxoacid metabolic processGO:00434362900.099
Yeast
cellular amino acid metabolic processGO:00065201070.077
Yeast
carboxylic acid metabolic processGO:00197522890.072
Yeast
response to nutrientGO:00075842480.071
cellular amino acid biosynthetic processGO:0008652320.065
response to extracellular stimulusGO:00099913800.065
small molecule biosynthetic processGO:00442831240.064
response to decreased oxygen levelsGO:00362932370.063
response to oxygen levelsGO:00704822650.062
organonitrogen compound biosynthetic processGO:19015661670.054
Yeast
macromolecular complex subunit organizationGO:00439333390.053
response to inorganic substanceGO:00100353770.053
organelle organizationGO:00069962660.051
organic acid biosynthetic processGO:0016053830.048
alpha amino acid biosynthetic processGO:1901607230.048
carboxylic acid biosynthetic processGO:0046394830.047
cellular ketone metabolic processGO:0042180510.046
carbohydrate derivative metabolic processGO:19011353460.044
cellular component assemblyGO:00226073600.044
cellular response to oxygen containing compoundGO:19017013860.043
cellular modified amino acid metabolic processGO:0006575610.043
Yeast
positive regulation of cell communicationGO:00106472710.042
apoptotic processGO:00069153810.042
response to bacteriumGO:00096172000.041
rna metabolic processGO:00160704060.041
response to hypoxiaGO:00016662310.041
reproductive processGO:00224143720.041
response to nutrient levelsGO:00316673700.041
amine metabolic processGO:0009308380.039
cofactor metabolic processGO:0051186950.038
Yeast
behaviorGO:00076102050.038
nucleobase containing small molecule metabolic processGO:00550863160.037
regulation of cellular amino acid metabolic processGO:000652120.036
carboxylic acid catabolic processGO:0046395490.035
single organism organelle organizationGO:19025891800.035
protein complex subunit organizationGO:00718223020.035
catabolic processGO:00090563510.035
regulation of molecular functionGO:00650093980.035
response to acid chemicalGO:00011012220.033
response to toxic substanceGO:00096361330.032
homeostatic processGO:00425923310.032
cellular amine metabolic processGO:0044106380.031
organic substance catabolic processGO:19015753160.031
purine containing compound metabolic processGO:00725212530.030
Yeast
response to peptide hormoneGO:00434342780.029
protein phosphorylationGO:00064683450.028
cellular catabolic processGO:00442482950.028
positive regulation of transportGO:00510502450.028
regulation of signal transductionGO:00099663180.028
gland developmentGO:00487321550.028
regulation of programmed cell deathGO:00430673410.027
sulfur compound metabolic processGO:0006790700.027
regulation of apoptotic processGO:00429813350.027
regulation of multicellular organismal developmentGO:20000263760.027
regulation of cellular protein metabolic processGO:00322682670.026
macromolecular complex assemblyGO:00650032730.026
defense responseGO:00069521940.026
rna biosynthetic processGO:00327743800.026
protein complex assemblyGO:00064612630.025
secretionGO:00469033070.025
positive regulation of nitrogen compound metabolic processGO:00511733340.025
regulation of cellular amine metabolic processGO:003323880.024
positive regulation of cellular amine metabolic processGO:003324030.024
response to biotic stimulusGO:00096072260.024
response to growth factorGO:00708481890.024
small molecule catabolic processGO:0044282590.024
head developmentGO:00603222470.024
protein oligomerizationGO:00512591910.023
central nervous system developmentGO:00074173110.023
regulation of cellular component organizationGO:00511283680.023
single organism reproductive processGO:00447022970.023
positive regulation of cell proliferationGO:00082842490.023
rhythmic processGO:00485111560.023
response to metal ionGO:00100382530.023
positive regulation of molecular functionGO:00440932300.023
programmed cell deathGO:00125013920.023
regulation of transcription dna templatedGO:00063553740.023
cellular response to growth factor stimulusGO:00713631620.022
response to transition metal nanoparticleGO:19902671220.022
transcription dna templatedGO:00063513770.022
protein complex biogenesisGO:00702712630.022
multicellular organismal reproductive processGO:00486092330.022
response to lipopolysaccharideGO:00324961910.022
response to external biotic stimulusGO:00432072210.022
organic acid catabolic processGO:0016054490.021
cellular homeostasisGO:00197252520.021
carbohydrate derivative biosynthetic processGO:19011371240.021
lipid metabolic processGO:00066292830.021
cellular response to organic cyclic compoundGO:00714072020.021
transmembrane transportGO:00550854120.021
response to vitaminGO:00332731310.021
reproductionGO:00000032450.020
folic acid containing compound metabolic processGO:0006760100.020
Yeast
regulation of cell differentiationGO:00455953200.020
cellular component biogenesisGO:00440853680.020
positive regulation of signalingGO:00230562700.020
cellular response to stressGO:00335542690.020
regulation of protein metabolic processGO:00512462890.019
regulation of cellular ketone metabolic processGO:0010565270.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
purine nucleoside metabolic processGO:00422781690.019
nitrogen compound transportGO:00717052290.019
cellular modified amino acid biosynthetic processGO:0042398180.019
neurological system processGO:00508772190.019
brain developmentGO:00074202470.019
single organism intracellular transportGO:19025821660.018
alpha amino acid catabolic processGO:1901606200.018
positive regulation of response to stimulusGO:00485842850.018
cellular response to endogenous stimulusGO:00714953770.018
positive regulation of biosynthetic processGO:00098913190.018
coenzyme metabolic processGO:0006732860.018
Yeast
anatomical structure morphogenesisGO:00096532980.018
regulation of rna biosynthetic processGO:20011413810.018
intracellular signal transductionGO:00355563140.018
macromolecule localizationGO:00330362520.018
pteridine containing compound metabolic processGO:0042558140.017
Yeast
positive regulation of phosphorus metabolic processGO:00105622620.017
organophosphate metabolic processGO:00196373700.017
positive regulation of cellular biosynthetic processGO:00313282950.017
negative regulation of programmed cell deathGO:00430691830.017
response to corticosteroidGO:00319602350.017
protein localizationGO:00081041910.017
neuron differentiationGO:00301823680.017
intracellular transportGO:00469071850.017
multicellular organism reproductionGO:00325042330.017
cellular amino acid catabolic processGO:0009063210.017
cellular response to nitrogen compoundGO:19016992100.017
response to molecule of bacterial originGO:00022371940.016
purine containing compound biosynthetic processGO:0072522850.016
Yeast
regulation of rna metabolic processGO:00512523910.016
nucleotide metabolic processGO:00091172790.016
regulation of phosphorus metabolic processGO:00511743490.016
ion transmembrane transportGO:00342203650.016
sex differentiationGO:00075481130.016
pigment biosynthetic processGO:004614840.016
Yeast
positive regulation of catalytic activityGO:00430851840.016
ribonucleotide metabolic processGO:00092592310.016
ribose phosphate metabolic processGO:00196932350.015
positive regulation of developmental processGO:00510942830.015
positive regulation of phosphorylationGO:00423271770.015
peptidyl amino acid modificationGO:00181931260.015
response to estrogenGO:00436272320.015
glycosyl compound metabolic processGO:19016571820.015
chemical homeostasisGO:00488782920.015
growthGO:00400071650.015
regulation of cell proliferationGO:00421273590.015
regulation of growthGO:00400081050.015
response to peptideGO:19016522920.015
sensory organ developmentGO:0007423740.015
regulation of phosphorylationGO:00423252480.015
cellular lipid metabolic processGO:00442552080.015
regulation of cell developmentGO:00602842630.015
purine nucleotide metabolic processGO:00061632290.015
negative regulation of response to stimulusGO:00485851550.014
single organism catabolic processGO:00447122830.014
nucleoside phosphate biosynthetic processGO:19012931020.014
cellular response to lipidGO:00713962010.014
response to ketoneGO:19016541820.014
multi organism reproductive processGO:00447032620.014
gonad developmentGO:00084061040.014
muscle structure developmentGO:0061061870.014
positive regulation of cell deathGO:00109421840.014
proteolysisGO:00065081750.014
neuron projection developmentGO:00311752730.014
regenerationGO:00310991630.014
nucleoside metabolic processGO:00091161790.014
ribonucleoside metabolic processGO:00091191740.014
cell projection organizationGO:00300303020.014
nucleoside phosphate metabolic processGO:00067532830.014
positive regulation of phosphate metabolic processGO:00459372620.014
response to carbohydrateGO:00097431830.014
regulation of protein phosphorylationGO:00019321830.014
cell growthGO:00160491040.014
axis specificationGO:000979840.014
cation transportGO:00068123820.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
regulation of secretionGO:00510462240.014
response to radiationGO:00093141370.014
cellular chemical homeostasisGO:00550822470.014
negative regulation of apoptotic processGO:00430661810.014
lipid biosynthetic processGO:00086101280.013
organic anion transportGO:00157111320.013
negative regulation of cell communicationGO:00106481580.013
nucleoside monophosphate biosynthetic processGO:0009124280.013
response to other organismGO:00517072200.013
negative regulation of cell deathGO:00605482290.013
cytoplasmic transportGO:00164821150.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
cell cell signalingGO:00072673350.013
development of primary female sexual characteristicsGO:0046545560.013
synaptic transmissionGO:00072682350.013
protein maturationGO:0051604680.013
regulation of intracellular signal transductionGO:19025312180.013
positive regulation of cellular protein metabolic processGO:00322701670.013
nucleotide biosynthetic processGO:0009165980.013
ion homeostasisGO:00508012120.013
nucleic acid templated transcriptionGO:00976593790.013
cellular response to cytokine stimulusGO:00713451270.012
circulatory system processGO:00030131830.012
organophosphate biosynthetic processGO:00904071430.012
regulation of cellular localizationGO:00603412630.012
cellular cation homeostasisGO:00300031800.012
regulation of canonical wnt signaling pathwayGO:006082840.012
tissue developmentGO:00098882520.012
cellular response to organonitrogen compoundGO:00714171970.012
regulation of nucleic acid templated transcriptionGO:19035063800.012
regulation of response to stressGO:00801341260.012
positive regulation of gene expressionGO:00106282440.012
anterior posterior pattern specificationGO:000995210.012
secretion by cellGO:00329402480.012
regulation of catalytic activityGO:00507903040.012
cellular response to abiotic stimulusGO:0071214850.012
single organism behaviorGO:00447081300.012
positive regulation of transcription dna templatedGO:00458931970.012
protein processingGO:0016485680.012
eye morphogenesisGO:004859240.012
reactive oxygen species metabolic processGO:0072593370.012
cellular response to hormone stimulusGO:00328702470.012
purine ribonucleotide metabolic processGO:00091502270.012
response to ethanolGO:00454711620.012
neuron developmentGO:00486662860.012
regulation of organelle organizationGO:0033043800.012
negative regulation of cellular component organizationGO:0051129830.012
female gonad developmentGO:0008585530.012
g protein coupled receptor signaling pathwayGO:00071862420.012
cellular ion homeostasisGO:00068731840.012
immune system processGO:00023762040.012
heart morphogenesisGO:000300730.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
response to glucocorticoidGO:00513842230.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
regulation of cell growthGO:0001558850.011
purine ribonucleoside metabolic processGO:00461281680.011
negative regulation of signalingGO:00230571570.011
positive regulation of rna metabolic processGO:00512542030.011
blood circulationGO:00080151830.011
defense response to gram negative bacteriumGO:005082930.011
hepaticobiliary system developmentGO:0061008900.011
development of primary sexual characteristicsGO:00451371070.011
regulation of ion transportGO:00432692450.011
cytoskeleton organizationGO:00070101110.011
metal ion homeostasisGO:00550651860.011
liver developmentGO:0001889900.011
anion transportGO:00068201780.011
embryonic pattern specificationGO:000988010.011
cell cycle checkpointGO:000007520.011
regulation of secretion by cellGO:19035302080.011
female sex differentiationGO:0046660590.011
cell morphogenesis involved in differentiationGO:00009041190.011
neuron projection morphogenesisGO:00488121220.011
positive regulation of rna biosynthetic processGO:19026801970.011
cation transmembrane transportGO:00986552630.011
positive regulation of protein metabolic processGO:00512471780.011
protein transportGO:00150311320.011
agingGO:00075682410.011
metal ion transportGO:00300012890.011
cation homeostasisGO:00550801950.011
cell part morphogenesisGO:00329901230.011
cognitionGO:0050890920.010
immune responseGO:00069551040.010
positive regulation of nucleic acid templated transcriptionGO:19035081970.010
regulation of neurogenesisGO:00507672470.010
regulation of nervous system developmentGO:00519602640.010
response to woundingGO:00096112540.010
ribonucleotide biosynthetic processGO:0009260850.010
cellular component movementGO:00069282480.010
cellular response to steroid hormone stimulusGO:0071383930.010
positive regulation of protein phosphorylationGO:00019341350.010
inflammatory responseGO:00069541500.010
developmental process involved in reproductionGO:00030061590.010
cellular protein localizationGO:00346131220.010
purine nucleotide biosynthetic processGO:0006164830.010
response to oxidative stressGO:00069791860.010
organonitrogen compound catabolic processGO:19015651790.010

Mthfd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.020
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
inherited metabolic disorderDOID:65500.012
sensory system diseaseDOID:005015500.011