Rattus norvegicus

0 known processes

Hfe2

hemochromatosis type 2 (juvenile) homolog (human)

(Aliases: MGC105910,Rgmc)

Hfe2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.209
organic acid metabolic processGO:00060822920.177
carboxylic acid metabolic processGO:00197522890.136
oxidation reduction processGO:00551143040.072
monocarboxylic acid metabolic processGO:00327871520.071
homeostatic processGO:00425923310.064
Human
regulation of cellular ketone metabolic processGO:0010565270.057
carbohydrate metabolic processGO:00059751300.051
single organism carbohydrate metabolic processGO:00447231180.050
cellular chemical homeostasisGO:00550822470.047
response to nutrient levelsGO:00316673700.045
regulation of cell proliferationGO:00421273590.043
response to decreased oxygen levelsGO:00362932370.042
cellular ketone metabolic processGO:0042180510.042
cellular metal ion homeostasisGO:00068751720.042
cation transportGO:00068123820.042
chemical homeostasisGO:00488782920.041
Human
monosaccharide metabolic processGO:0005996610.039
single organism biosynthetic processGO:00447113420.037
response to nutrientGO:00075842480.036
reproductionGO:00000032450.035
proteolysisGO:00065081750.034
negative regulation of cellular metabolic processGO:00313242810.034
anion transportGO:00068201780.034
response to inorganic substanceGO:00100353770.033
regulation of catalytic activityGO:00507903040.032
single organism reproductive processGO:00447022970.032
cellular lipid metabolic processGO:00442552080.032
response to acid chemicalGO:00011012220.032
multicellular organismal reproductive processGO:00486092330.032
response to estrogenGO:00436272320.032
response to extracellular stimulusGO:00099913800.032
response to peptideGO:19016522920.032
metal ion transportGO:00300012890.032
reproductive processGO:00224143720.031
cellular component assemblyGO:00226073600.031
response to metal ionGO:00100382530.031
agingGO:00075682410.031
multicellular organism reproductionGO:00325042330.030
regulation of metal ion transportGO:00109591180.030
hexose metabolic processGO:0019318580.030
nucleic acid templated transcriptionGO:00976593790.030
ion homeostasisGO:00508012120.030
Human
organic substance catabolic processGO:19015753160.029
multi organism reproductive processGO:00447032620.028
response to peptide hormoneGO:00434342780.028
cellular homeostasisGO:00197252520.028
cellular ion homeostasisGO:00068731840.028
cellular component biogenesisGO:00440853680.028
regulation of ion transportGO:00432692450.027
regulation of programmed cell deathGO:00430673410.027
metal ion homeostasisGO:00550651860.027
Human
transmembrane transportGO:00550854120.027
cellular response to stressGO:00335542690.026
cholesterol homeostasisGO:004263230.026
lipid biosynthetic processGO:00086101280.026
cellular cation homeostasisGO:00300031800.026
multi multicellular organism processGO:00447061380.025
cellular amino acid metabolic processGO:00065201070.025
response to carbohydrateGO:00097431830.025
fatty acid metabolic processGO:0006631990.025
catabolic processGO:00090563510.025
macromolecular complex assemblyGO:00650032730.025
growthGO:00400071650.025
intracellular transportGO:00469071850.024
carbohydrate catabolic processGO:0016052400.024
central nervous system developmentGO:00074173110.024
negative regulation of metabolic processGO:00098923310.024
divalent inorganic cation transportGO:00725111340.024
response to monosaccharideGO:00342841590.024
amine metabolic processGO:0009308380.024
sterol homeostasisGO:005509230.024
negative regulation of gene expressionGO:00106291990.024
rna metabolic processGO:00160704060.024
response to hexoseGO:00097461440.023
cellular response to oxygen containing compoundGO:19017013860.023
calcium ion homeostasisGO:00550741620.023
regenerationGO:00310991630.023
regulation of cellular amino acid metabolic processGO:000652120.023
response to hypoxiaGO:00016662310.023
brain developmentGO:00074202470.023
organic anion transportGO:00157111320.023
cellular response to nitrogen compoundGO:19016992100.023
regulation of molecular functionGO:00650093980.023
response to oxygen levelsGO:00704822650.023
cellular amine metabolic processGO:0044106380.022
negative regulation of macromolecule metabolic processGO:00106052600.022
response to woundingGO:00096112540.022
secretionGO:00469033070.022
glucose metabolic processGO:0006006520.021
regulation of apoptotic processGO:00429813350.021
organic acid biosynthetic processGO:0016053830.021
lipid metabolic processGO:00066292830.021
single organism catabolic processGO:00447122830.021
response to glucoseGO:00097491360.021
positive regulation of nitrogen compound metabolic processGO:00511733340.021
divalent inorganic cation homeostasisGO:00725071650.021
carbohydrate derivative metabolic processGO:19011353460.021
carboxylic acid biosynthetic processGO:0046394830.020
positive regulation of cell proliferationGO:00082842490.019
regulation of rna biosynthetic processGO:20011413810.019
nitrogen compound transportGO:00717052290.019
small molecule biosynthetic processGO:00442831240.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
protein complex assemblyGO:00064612630.018
response to glucocorticoidGO:00513842230.018
regulation of cellular component organizationGO:00511283680.018
carboxylic acid transportGO:00469421150.018
cell projection organizationGO:00300303020.018
positive regulation of biosynthetic processGO:00098913190.018
cellular response to organonitrogen compoundGO:00714171970.018
macromolecular complex subunit organizationGO:00439333390.018
positive regulation of cellular amine metabolic processGO:003324030.018
regulation of homeostatic processGO:00328441010.018
lipid storageGO:001991510.018
divalent metal ion transportGO:00708381320.018
regulation of catabolic processGO:00098941130.018
regulation of cellular amine metabolic processGO:003323880.017
fatty acid oxidationGO:0019395290.017
calcium ion transportGO:00068161310.017
regulation of hormone levelsGO:00108171870.017
positive regulation of cell developmentGO:00107201760.017
negative regulation of cell deathGO:00605482290.017
intracellular signal transductionGO:00355563140.017
negative regulation of programmed cell deathGO:00430691830.017
regulation of cellular localizationGO:00603412630.017
organophosphate metabolic processGO:00196373700.017
regulation of calcium ion transportGO:0051924770.017
cell growthGO:00160491040.016
sexual reproductionGO:00199531480.016
cellular response to hormone stimulusGO:00328702470.016
reactive nitrogen species metabolic processGO:200105710.016
cellular catabolic processGO:00442482950.016
multicellular organism growthGO:003526410.016
regulation of cell developmentGO:00602842630.016
ras protein signal transductionGO:0007265290.016
positive regulation of cell differentiationGO:00455972170.016
regulation of cell differentiationGO:00455953200.016
small gtpase mediated signal transductionGO:0007264360.016
head developmentGO:00603222470.015
defense responseGO:00069521940.015
protein complex subunit organizationGO:00718223020.015
regulation of transcription dna templatedGO:00063553740.015
response to purine containing compoundGO:00140741260.015
single organism carbohydrate catabolic processGO:0044724400.015
cytoplasmic transportGO:00164821150.015
cellular response to peptideGO:19016531330.015
regulation of nervous system developmentGO:00519602640.015
negative regulation of apoptotic processGO:00430661810.015
apoptotic processGO:00069153810.015
response to corticosteroidGO:00319602350.015
positive regulation of molecular functionGO:00440932300.015
regulation of multicellular organismal developmentGO:20000263760.015
cation homeostasisGO:00550801950.015
Human
generation of precursor metabolites and energyGO:0006091620.015
regulation of protein maturationGO:1903317500.014
ion transmembrane transportGO:00342203650.014
cellular calcium ion homeostasisGO:00068741600.014
response to ketoneGO:19016541820.014
regulation of growthGO:00400081050.014
response to estradiolGO:00323551640.014
regulation of peptide transportGO:0090087870.014
positive regulation of transportGO:00510502450.014
lipid localizationGO:0010876620.014
regulation of fatty acid metabolic processGO:0019217180.014
protein maturationGO:0051604680.014
response to cytokineGO:00340972150.014
response to insulinGO:00328681330.014
regulation of protein metabolic processGO:00512462890.014
muscle system processGO:00030121150.014
regulation of reactive oxygen species biosynthetic processGO:190342650.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
female pregnancyGO:00075651220.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
sequestering of metal ionGO:005123890.014
cellular response to vitamin eGO:007130630.014
regulation of neurogenesisGO:00507672470.014
blood circulationGO:00080151830.014
programmed cell deathGO:00125013920.014
response to molecule of bacterial originGO:00022371940.014
regulation of cell projection organizationGO:00313441750.013
organ regenerationGO:00311001010.013
response to ethanolGO:00454711620.013
negative regulation of transportGO:00510511360.013
cellular response to external stimulusGO:00714961180.013
regulation of hydrolase activityGO:00513361430.013
lipid transportGO:0006869610.013
response to bacteriumGO:00096172000.013
circulatory system processGO:00030131830.013
macromolecule localizationGO:00330362520.013
cellular polysaccharide metabolic processGO:0044264230.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
regulation of rna metabolic processGO:00512523910.013
positive regulation of gene expressionGO:00106282440.013
muscle contractionGO:0006936880.013
positive regulation of developmental processGO:00510942830.013
positive regulation of phosphorus metabolic processGO:00105622620.013
negative regulation of biosynthetic processGO:00098901680.013
positive regulation of catalytic activityGO:00430851840.013
organic acid transportGO:00158491160.013
polysaccharide metabolic processGO:0005976250.013
sequestering of calcium ionGO:005120880.013
positive regulation of neurogenesisGO:00507691650.012
cell cell signalingGO:00072673350.012
response to campGO:0051591910.012
monocarboxylic acid transportGO:0015718520.012
monovalent inorganic cation transportGO:00156721720.012
protein processingGO:0016485680.012
maintenance of locationGO:0051235170.012
transcription dna templatedGO:00063513770.012
gamete generationGO:00072761240.012
organic hydroxy compound metabolic processGO:19016151150.012
reactive oxygen species metabolic processGO:0072593370.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
positive regulation of nervous system developmentGO:00519621780.012
regulation of nucleic acid templated transcriptionGO:19035063800.012
muscle cell proliferationGO:0033002840.012
regulation of ion homeostasisGO:2000021630.012
energy reserve metabolic processGO:0006112250.012
developmental process involved in reproductionGO:00030061590.012
glycogen metabolic processGO:0005977230.012
peptide transportGO:0015833970.012
negative regulation of response to stimulusGO:00485851550.012
regulation of protein processingGO:0070613500.012
cell cycle checkpointGO:000007520.012
cytosolic calcium ion homeostasisGO:00514801400.012
negative regulation of innate immune responseGO:004582440.012
reactive oxygen species biosynthetic processGO:190340980.012
regulation of fat cell differentiationGO:004559830.012
transmission of nerve impulseGO:0019226420.012
rhythmic processGO:00485111560.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
regulation of phosphorus metabolic processGO:00511743490.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
protein oligomerizationGO:00512591910.012
negative regulation of multicellular organismal processGO:00512412030.011
neuron differentiationGO:00301823680.011
regulation of phagocytosis engulfmentGO:006009940.011
cellular carbohydrate metabolic processGO:0044262720.011
spermatogenesisGO:0007283990.011
response to organophosphorusGO:00466831020.011
action potentialGO:0001508540.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
regulation of cell growthGO:0001558850.011
response to vitaminGO:00332731310.011
cellular response to ketoneGO:1901655510.011
epithelial cell proliferationGO:0050673540.011
regulation of signal transductionGO:00099663180.011
positive regulation of cellular component organizationGO:00511302000.011
rho protein signal transductionGO:0007266110.011
neuron projection developmentGO:00311752730.011
neuronal action potentialGO:0019228350.011
single organism intracellular transportGO:19025821660.011
neuron developmentGO:00486662860.011
negative regulation of cellular protein metabolic processGO:00322691060.011
response to lipopolysaccharideGO:00324961910.011
multicellular organismal signalingGO:0035637440.011
negative regulation of cellular biosynthetic processGO:00313271610.011
regulation of epithelial cell proliferationGO:0050678490.011
positive regulation of rna metabolic processGO:00512542030.011
cellular response to insulin stimulusGO:0032869810.010
nucleobase containing small molecule metabolic processGO:00550863160.010
protein homooligomerizationGO:0051260910.010
jak stat cascadeGO:0007259260.010
reproductive structure developmentGO:00486081280.010
protein phosphorylationGO:00064683450.010
cellular response to endogenous stimulusGO:00714953770.010
negative regulation of catalytic activityGO:00430861030.010
negative regulation of cell cycle phase transitionGO:190198840.010
smooth muscle cell proliferationGO:0048659770.010
behaviorGO:00076102050.010
coenzyme metabolic processGO:0006732860.010
regulation of system processGO:00440572080.010
response to transition metal nanoparticleGO:19902671220.010
protein complex biogenesisGO:00702712630.010
regulation of secretionGO:00510462240.010
cation transmembrane transportGO:00986552630.010
regulation of carbohydrate metabolic processGO:0006109410.010
cellular glucan metabolic processGO:0006073230.010
negative regulation of protein metabolic processGO:00512481140.010

Hfe2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:42300.022
disease of anatomical entityDOID:700.022
muscular diseaseDOID:008000000.022
musculoskeletal system diseaseDOID:1700.022
muscle tissue diseaseDOID:6600.022
disease of metabolismDOID:001466700.021
Human
inherited metabolic disorderDOID:65500.014
Human
nervous system diseaseDOID:86300.010