Rattus norvegicus

5 known processes

Akr1d1

aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

Akr1d1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to inorganic substanceGO:00100353770.391
Rat
regulation of hormone levelsGO:00108171870.353
Human Rat
response to peptideGO:19016522920.332
Rat
cellular response to hormone stimulusGO:00328702470.298
response to peptide hormoneGO:00434342780.277
protein complex biogenesisGO:00702712630.258
biphenyl catabolic processGO:007098020.228
cellular response to peptide hormone stimulusGO:00713751200.212
blood circulationGO:00080151830.189
transmembrane transportGO:00550854120.176
response to nutrient levelsGO:00316673700.172
cellular response to lipidGO:00713962010.138
muscle cell proliferationGO:0033002840.131
Rat
response to extracellular stimulusGO:00099913800.130
response to acid chemicalGO:00011012220.128
Rat
regulation of cell proliferationGO:00421273590.120
Rat
heterocycle catabolic processGO:00467001670.119
regulation of ion transportGO:00432692450.117
oxoacid metabolic processGO:00434362900.113
Human
ion transmembrane transportGO:00342203650.110
carbohydrate derivative metabolic processGO:19011353460.107
cellular response to steroid hormone stimulusGO:0071383930.107
cellular response to oxygen containing compoundGO:19017013860.107
Rat
cellular response to organonitrogen compoundGO:00714171970.106
Rat
response to estradiolGO:00323551640.103
nitrogen compound transportGO:00717052290.098
circulatory system processGO:00030131830.097
response to estrogenGO:00436272320.097
Rat
macromolecular complex assemblyGO:00650032730.096
response to bacteriumGO:00096172000.095
response to vitaminGO:00332731310.094
steroid metabolic processGO:0008202730.088
Human
response to corticosteroidGO:00319602350.087
response to ketoneGO:19016541820.086
Rat
response to biotic stimulusGO:00096072260.085
agingGO:00075682410.085
aromatic compound catabolic processGO:00194391680.085
gland developmentGO:00487321550.084
nucleotide metabolic processGO:00091172790.080
catabolic processGO:00090563510.080
Human
lipid metabolic processGO:00066292830.079
Human Rat
cellular component biogenesisGO:00440853680.078
carboxylic acid metabolic processGO:00197522890.077
Human
single organism biosynthetic processGO:00447113420.077
Human Rat
single organism reproductive processGO:00447022970.071
Rat
hormone metabolic processGO:0042445690.070
Human Rat
secretionGO:00469033070.067
organic substance catabolic processGO:19015753160.066
Human
cofactor metabolic processGO:0051186950.065
multi multicellular organism processGO:00447061380.065
Rat
protein oligomerizationGO:00512591910.062
cellular response to organic cyclic compoundGO:00714072020.062
locomotionGO:00400112370.062
response to glucocorticoidGO:00513842230.062
cellular response to insulin stimulusGO:0032869810.061
organic acid metabolic processGO:00060822920.061
Human
negative regulation of apoptotic processGO:00430661810.060
cellular component assemblyGO:00226073600.060
regulation of molecular functionGO:00650093980.060
positive regulation of nitrogen compound metabolic processGO:00511733340.057
negative regulation of cell deathGO:00605482290.057
anion transportGO:00068201780.056
cellular hormone metabolic processGO:0034754490.056
Human Rat
cellular response to alcoholGO:0097306870.055
head developmentGO:00603222470.055
Rat
cellular response to endogenous stimulusGO:00714953770.055
Rat
metal ion transportGO:00300012890.054
g protein coupled receptor signaling pathwayGO:00071862420.054
response to insulinGO:00328681330.054
response to oxygen levelsGO:00704822650.051
organic anion transportGO:00157111320.051
cellular amino acid metabolic processGO:00065201070.051
steroid catabolic processGO:000670650.050
Human
response to lipopolysaccharideGO:00324961910.049
inorganic cation transmembrane transportGO:00986622020.049
positive regulation of multicellular organismal processGO:00512403870.049
regulation of secretion by cellGO:19035302080.048
positive regulation of biosynthetic processGO:00098913190.048
apoptotic processGO:00069153810.048
sodium ion transmembrane transportGO:0035725670.047
nucleoside phosphate catabolic processGO:19012921400.047
lipid biosynthetic processGO:00086101280.047
Human
regulation of system processGO:00440572080.046
protein complex assemblyGO:00064612630.046
positive regulation of secretion by cellGO:19035321280.046
organophosphate metabolic processGO:00196373700.045
nucleobase containing small molecule metabolic processGO:00550863160.044
reproductive processGO:00224143720.044
Rat
cellular catabolic processGO:00442482950.044
positive regulation of transportGO:00510502450.044
cellular ion homeostasisGO:00068731840.044
cellular response to stressGO:00335542690.043
Rat
regulation of secretionGO:00510462240.042
hormone transportGO:00099141210.042
response to external biotic stimulusGO:00432072210.042
organophosphate catabolic processGO:00464341480.042
response to molecule of bacterial originGO:00022371940.041
regulation of programmed cell deathGO:00430673410.041
4 chlorobiphenyl metabolic processGO:001888010.040
cellular response to peptideGO:19016531330.040
Rat
cation transmembrane transportGO:00986552630.040
purine nucleotide metabolic processGO:00061632290.039
purine ribonucleotide metabolic processGO:00091502270.039
cation transportGO:00068123820.039
purine containing compound metabolic processGO:00725212530.038
central nervous system developmentGO:00074173110.038
Rat
vitamin transportGO:0051180140.038
cell morphogenesis involved in differentiationGO:00009041190.038
single organism catabolic processGO:00447122830.038
Human
macromolecular complex subunit organizationGO:00439333390.037
programmed cell deathGO:00125013920.037
homeostatic processGO:00425923310.037
Rat
divalent metal ion transportGO:00708381320.037
macromolecule localizationGO:00330362520.037
cellular response to nitrogen compoundGO:19016992100.037
Rat
behaviorGO:00076102050.037
regulation of cellular localizationGO:00603412630.036
cation homeostasisGO:00550801950.036
regulation of apoptotic processGO:00429813350.036
regulation of phosphorus metabolic processGO:00511743490.036
response to ethanolGO:00454711620.036
cell cell signalingGO:00072673350.036
negative regulation of macromolecule metabolic processGO:00106052600.036
response to nutrientGO:00075842480.035
transcription dna templatedGO:00063513770.035
tripeptide transportGO:004293920.035
phenylpropanoid catabolic processGO:004627130.035
response to other organismGO:00517072200.035
response to carbohydrateGO:00097431830.035
ion homeostasisGO:00508012120.034
response to xenobiotic stimulusGO:0009410230.034
response to metal ionGO:00100382530.034
cellular nitrogen compound catabolic processGO:00442701630.034
developmental process involved in reproductionGO:00030061590.034
cellular ketone metabolic processGO:0042180510.034
cellular response to external stimulusGO:00714961180.034
response to vitamin dGO:0033280340.033
secretion by cellGO:00329402480.033
protein complex subunit organizationGO:00718223020.033
hepaticobiliary system developmentGO:0061008900.033
metal ion homeostasisGO:00550651860.032
transmission of nerve impulseGO:0019226420.032
cell projection organizationGO:00300303020.032
neurological system processGO:00508772190.032
tissue developmentGO:00098882520.032
regulation of catalytic activityGO:00507903040.031
nucleoside catabolic processGO:00091641260.031
cytosolic calcium ion homeostasisGO:00514801400.031
regulation of epithelial cell proliferationGO:0050678490.031
purine ribonucleoside triphosphate metabolic processGO:00092051400.031
purine nucleoside metabolic processGO:00422781690.031
coenzyme metabolic processGO:0006732860.031
protein transportGO:00150311320.030
chlorinated hydrocarbon metabolic processGO:004219640.030
negative regulation of cellular metabolic processGO:00313242810.030
cellular response to ketoneGO:1901655510.030
Rat
organic cyclic compound catabolic processGO:19013611750.030
Human
cellular response to xenobiotic stimulusGO:0071466190.030
diterpenoid metabolic processGO:0016101330.030
Rat
divalent inorganic cation homeostasisGO:00725071650.030
negative regulation of metabolic processGO:00098923310.029
cellular response to glucocorticoid stimulusGO:0071385680.028
terpenoid metabolic processGO:0006721370.028
Rat
brain developmentGO:00074202470.028
Rat
regulation of metal ion transportGO:00109591180.028
sulfur compound metabolic processGO:0006790700.028
positive regulation of phosphate metabolic processGO:00459372620.027
organelle organizationGO:00069962660.027
organonitrogen compound catabolic processGO:19015651790.027
phenol containing compound metabolic processGO:0018958300.027
Rat
peptide secretionGO:0002790860.027
multi organism reproductive processGO:00447032620.027
Rat
anatomical structure morphogenesisGO:00096532980.027
positive regulation of cell communicationGO:00106472710.027
Rat
glycosyl compound metabolic processGO:19016571820.027
stress activated protein kinase signaling cascadeGO:0031098370.027
Rat
glycosyl compound catabolic processGO:19016581260.027
smooth muscle cell proliferationGO:0048659770.027
Rat
regulation of anatomical structure sizeGO:00900661350.027
coumarin catabolic processGO:004622630.026
regulation of hormone secretionGO:00468831060.026
divalent inorganic cation transportGO:00725111340.026
regulation of cellular component organizationGO:00511283680.026
lipid localizationGO:0010876620.026
cellular divalent inorganic cation homeostasisGO:00725031620.026
regulation of cell differentiationGO:00455953200.025
liver developmentGO:0001889900.025
ribonucleotide catabolic processGO:00092611360.025
calcium ion homeostasisGO:00550741620.025
regulation of blood circulationGO:19035221100.025
positive regulation of blood circulationGO:1903524650.025
alcohol metabolic processGO:0006066770.025
Human Rat
small molecule biosynthetic processGO:00442831240.025
Human Rat
rna biosynthetic processGO:00327743800.025
organic hydroxy compound metabolic processGO:19016151150.025
Human Rat
regulation of transcription dna templatedGO:00063553740.024
response to toxic substanceGO:00096361330.024
4 nitrophenol metabolic processGO:001896010.024
ribonucleotide metabolic processGO:00092592310.024
peptide transportGO:0015833970.024
negative regulation of programmed cell deathGO:00430691830.024
regulation of growthGO:00400081050.024
cellular chemical homeostasisGO:00550822470.024
multicellular organismal reproductive processGO:00486092330.024
Rat
regulation of blood pressureGO:0008217830.024
response to starvationGO:0042594590.023
neuron differentiationGO:00301823680.023
purine nucleotide catabolic processGO:00061951360.023
regulation of purine nucleotide metabolic processGO:19005421150.023
cellular cation homeostasisGO:00300031800.023
single organism intracellular transportGO:19025821660.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
regulation of peptide hormone secretionGO:0090276800.023
protein homooligomerizationGO:0051260910.023
response to monosaccharideGO:00342841590.023
defense responseGO:00069521940.023
purine ribonucleoside catabolic processGO:00461301240.023
insulin secretionGO:0030073690.022
regulation of phosphate metabolic processGO:00192203490.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
positive regulation of molecular functionGO:00440932300.022
regulation of peptide transportGO:0090087870.022
developmental growthGO:00485891000.022
regulation of rna metabolic processGO:00512523910.022
single organism carbohydrate metabolic processGO:00447231180.022
Rat
catecholamine transportGO:0051937370.022
ribonucleoside triphosphate metabolic processGO:00091991410.022
nucleic acid templated transcriptionGO:00976593790.022
nucleoside triphosphate catabolic processGO:00091431230.022
carbohydrate derivative catabolic processGO:19011361470.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
vesicle mediated transportGO:00161921810.022
muscle system processGO:00030121150.022
hormone secretionGO:00468791150.021
ribose phosphate metabolic processGO:00196932350.021
positive regulation of transcription dna templatedGO:00458931970.021
rna metabolic processGO:00160704060.021
positive regulation of peptide hormone secretionGO:0090277500.021
cellular response to extracellular stimulusGO:0031668730.021
lipid transportGO:0006869610.021
negative regulation of molecular functionGO:00440921330.021
growthGO:00400071650.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
negative regulation of biosynthetic processGO:00098901680.021
response to campGO:0051591910.020
hormone catabolic processGO:004244720.020
amide transportGO:00428861050.020
drug transmembrane transportGO:0006855130.020
organic hydroxy compound transportGO:0015850770.020
purine containing compound catabolic processGO:00725231380.020
single organism behaviorGO:00447081300.020
negative regulation of transportGO:00510511360.020
ribonucleoside triphosphate catabolic processGO:00092031220.020
regulation of neuron deathGO:19012141150.020
toxin catabolic processGO:000940710.020
ribonucleoside catabolic processGO:00424541260.020
cellular homeostasisGO:00197252520.020
regulation of homeostatic processGO:00328441010.020
multicellular organism reproductionGO:00325042330.019
Rat
regulation of rna biosynthetic processGO:20011413810.019
nucleobase containing compound catabolic processGO:00346551520.019
monocarboxylic acid transportGO:0015718520.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
response to activityGO:0014823730.019
negative regulation of nitrogen compound metabolic processGO:00511721610.018
halogenated hydrocarbon metabolic processGO:004219740.018
cellular amine metabolic processGO:0044106380.018
linoleic acid metabolic processGO:004365140.018
cytoplasmic transportGO:00164821150.018
regulation of cellular ketone metabolic processGO:0010565270.018
response to decreased oxygen levelsGO:00362932370.018
response to glucoseGO:00097491360.018
cellular lipid metabolic processGO:00442552080.018
Rat
purine ribonucleotide catabolic processGO:00091541360.018
cellular calcium ion homeostasisGO:00068741600.018
nucleoside phosphate metabolic processGO:00067532830.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
nucleoside metabolic processGO:00091161790.017
cellular response to testosterone stimulusGO:007139450.017
nucleoside triphosphate metabolic processGO:00091411440.017
positive regulation of phosphorus metabolic processGO:00105622620.017
purine ribonucleoside metabolic processGO:00461281680.017
signal releaseGO:00230611450.017
cellular metal ion homeostasisGO:00068751720.017
glutathione transportGO:003463520.017
localization of cellGO:00516742020.017
epithelium developmentGO:0060429960.017
reproductive system developmentGO:00614581280.017
multicellular organism growthGO:003526410.017
synaptic transmissionGO:00072682350.017
regulation of body fluid levelsGO:0050878900.017
cell motilityGO:00488702020.017
negative regulation of monooxygenase activityGO:003276930.017
neuron developmentGO:00486662860.016
feeding behaviorGO:0007631530.016
anion transmembrane transportGO:0098656770.016
negative regulation of secretionGO:0051048820.016
circadian sleep wake cycle processGO:0022410210.016
reproductionGO:00000032450.016
Rat
response to hypoxiaGO:00016662310.016
regulation of immune system processGO:00026821230.016
cellular response to corticosteroid stimulusGO:0071384690.016
positive regulation of catalytic activityGO:00430851840.016
response to transition metal nanoparticleGO:19902671220.016
cellular response to abiotic stimulusGO:0071214850.016
positive regulation of gene expressionGO:00106282440.016
regulation of signal transductionGO:00099663180.016
Rat
negative regulation of protein metabolic processGO:00512481140.016
positive regulation of catabolic processGO:0009896780.016
calcitriol biosynthetic process from calciolGO:003637820.016
regulation of locomotionGO:00400121480.016
regenerationGO:00310991630.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
response to hexoseGO:00097461440.015
cellular component movementGO:00069282480.015
xenobiotic metabolic processGO:0006805190.015
nucleoside monophosphate catabolic processGO:0009125560.015
gonad developmentGO:00084061040.015
nuclear transportGO:0051169490.015
regulation of phosphorylationGO:00423252480.015
neuron deathGO:00709971270.015
positive regulation of cellular biosynthetic processGO:00313282950.015
multicellular organismal signalingGO:0035637440.015
kidney developmentGO:0001822670.015
Rat
immune responseGO:00069551040.015
cardiac muscle contractionGO:0060048270.015
organ regenerationGO:00311001010.015
transcription from rna polymerase ii promoterGO:00063662520.015
positive regulation of nucleotide metabolic processGO:0045981910.015
positive regulation of serotonin secretionGO:001406410.015
heart morphogenesisGO:000300730.015
positive regulation of homeostatic processGO:0032846490.015
regulation of smooth muscle cell proliferationGO:0048660750.015
Rat
negative regulation of gene expressionGO:00106291990.015
positive regulation of developmental processGO:00510942830.014
striated muscle tissue developmentGO:0014706580.014
regulation of protein metabolic processGO:00512462890.014
isoprenoid metabolic processGO:0006720450.014
Rat
monoamine transportGO:0015844430.014
chemical homeostasisGO:00488782920.014
rhythmic processGO:00485111560.014
protein localizationGO:00081041910.014
regulation of cellular amine metabolic processGO:003323880.014
carbohydrate biosynthetic processGO:0016051420.014
Rat
cellular component morphogenesisGO:00329891550.014
estrogen catabolic processGO:000671110.014
sodium ion transportGO:0006814820.014
positive regulation of response to stimulusGO:00485842850.014
Rat
positive regulation of cellular component organizationGO:00511302000.014
carboxylic acid transportGO:00469421150.014
telencephalon developmentGO:0021537620.014
Rat
anatomical structure formation involved in morphogenesisGO:0048646830.014
regulation of peptide secretionGO:0002791820.013
response to alkaloidGO:00432791320.013
establishment of protein localizationGO:00451841410.013
organic hydroxy compound biosynthetic processGO:1901617510.013
Human Rat
epithelial cell differentiationGO:0030855710.013
regulation of nervous system developmentGO:00519602640.013
establishment of protein localization to organelleGO:0072594440.013
positive regulation of protein metabolic processGO:00512471780.013
cell communication involved in cardiac conductionGO:008606520.013
oligopeptide transportGO:000685740.013
reproductive structure developmentGO:00486081280.013
lipid storageGO:001991510.013
single organism nuclear importGO:1902593350.013
regulation of catecholamine secretionGO:0050433320.013
protein targetingGO:0006605610.013
acyl coa metabolic processGO:0006637280.013
positive regulation of blood pressureGO:0045777310.013
neuronal action potentialGO:0019228350.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
response to growth factorGO:00708481890.013
protein processingGO:0016485680.013
positive regulation of smooth muscle cell proliferationGO:0048661510.013
Rat
positive regulation of programmed cell deathGO:00430681570.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
response to organophosphorusGO:00466831020.013
calcium ion transportGO:00068161310.012
signal transduction by phosphorylationGO:00230141440.012
single organism organelle organizationGO:19025891800.012
kidney morphogenesisGO:0060993130.012
positive regulation of rna metabolic processGO:00512542030.012
response to insecticideGO:0017085210.012
regulation of cellular protein metabolic processGO:00322682670.012
neuron apoptotic processGO:0051402880.012
response to corticosteroneGO:0051412400.012
tissue remodelingGO:0048771400.012
intracellular signal transductionGO:00355563140.012
Rat
cellular response to nutrient levelsGO:0031669600.012
response to testosteroneGO:0033574550.012
regulation of neurogenesisGO:00507672470.012
thioester metabolic processGO:0035383280.012
peptide hormone secretionGO:0030072840.012
response to woundingGO:00096112540.012
cellular macromolecule localizationGO:00707271220.012
regulation of nucleic acid templated transcriptionGO:19035063800.012
positive regulation of cell developmentGO:00107201760.012
axis specificationGO:000979840.012
regulation of nucleoside metabolic processGO:0009118660.012
inorganic anion transportGO:0015698410.012
regulation of insulin secretionGO:0050796650.012
carbohydrate metabolic processGO:00059751300.012
Rat
gamete generationGO:00072761240.012
neuron projection developmentGO:00311752730.012
dopamine secretionGO:0014046150.012
defense response to gram negative bacteriumGO:005082930.012
cell part morphogenesisGO:00329901230.012
heart developmentGO:0007507720.011
cell migrationGO:00164771970.011
sulfationGO:005192320.011
response to cytokineGO:00340972150.011
development of primary sexual characteristicsGO:00451371070.011
monocarboxylic acid biosynthetic processGO:0072330480.011
Human
cellular macromolecular complex assemblyGO:0034622580.011
positive regulation of cell growthGO:0030307440.011
neural crest cell differentiationGO:001403320.011
regulation of lipid metabolic processGO:0019216680.011
regulation of cellular amino acid metabolic processGO:000652120.011
positive regulation of ion transportGO:0043270940.011
digestive tract developmentGO:0048565390.011
sterol homeostasisGO:005509230.011
sex differentiationGO:00075481130.011
activation of protein kinase activityGO:0032147470.011
response to fluorideGO:190261730.011
positive regulation of rna biosynthetic processGO:19026801970.011
cell morphogenesisGO:00009021420.011
embryonic pattern specificationGO:000988010.011
positive regulation of apoptotic processGO:00430651540.011
regulation of systemic arterial blood pressureGO:0003073300.011
inflammatory responseGO:00069541500.011
regulation of multicellular organismal developmentGO:20000263760.011
regulation of hydrolase activityGO:00513361430.011
endocrine system developmentGO:0035270300.011
intracellular protein transportGO:0006886790.011
dendrite developmentGO:0016358720.011
female pregnancyGO:00075651220.011
Rat
actin filament based processGO:0030029860.011
carbohydrate derivative biosynthetic processGO:19011371240.011
inorganic ion transmembrane transportGO:00986602290.011
purine nucleoside monophosphate metabolic processGO:0009126840.011
regulation of neuron apoptotic processGO:0043523830.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
lipid modificationGO:0030258520.011
estrogen metabolic processGO:0008210110.011
response to foodGO:0032094270.011
regulation of neuron differentiationGO:00456642080.010
amine metabolic processGO:0009308380.010
regulation of ion homeostasisGO:2000021630.010
nucleoside monophosphate metabolic processGO:0009123930.010
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.010
regulation of carbohydrate metabolic processGO:0006109410.010
response to vitamin aGO:0033189360.010
negative regulation of catalytic activityGO:00430861030.010
regulation of proteolysisGO:0030162660.010
regulation of transferase activityGO:00513381230.010
proteolysisGO:00065081750.010
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.010
taxisGO:0042330670.010
inner medullary collecting duct developmentGO:007206110.010
Rat
regulation of catabolic processGO:00098941130.010

Akr1d1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hypertensionDOID:1076300.022
vascular diseaseDOID:17800.022
essential hypertensionDOID:1082500.022
disease of anatomical entityDOID:700.022
cardiovascular system diseaseDOID:128700.022
artery diseaseDOID:005082800.022
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.014
endocrine system diseaseDOID:2800.011
brain diseaseDOID:93600.010