Rattus norvegicus

55 known processes

Pde8b

phosphodiesterase 8B

(Aliases: RNPDE8B)

Pde8b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.156
Rat
regulation of signal transductionGO:00099663180.120
positive regulation of cellular biosynthetic processGO:00313282950.095
regulation of phosphorus metabolic processGO:00511743490.093
protein phosphorylationGO:00064683450.093
positive regulation of nitrogen compound metabolic processGO:00511733340.085
lipid metabolic processGO:00066292830.083
Mouse
regulation of protein metabolic processGO:00512462890.079
metal ion transportGO:00300012890.077
transmembrane transportGO:00550854120.076
positive regulation of nucleic acid templated transcriptionGO:19035081970.075
positive regulation of cell communicationGO:00106472710.074
neuron differentiationGO:00301823680.073
negative regulation of metabolic processGO:00098923310.072
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353190.071
negative regulation of cellular metabolic processGO:00313242810.070
Mouse
positive regulation of biosynthetic processGO:00098913190.070
regulation of cellular component organizationGO:00511283680.069
positive regulation of signalingGO:00230562700.068
chemical homeostasisGO:00488782920.067
calcium ion homeostasisGO:00550741620.067
metal ion homeostasisGO:00550651860.066
cellular metal ion homeostasisGO:00068751720.066
cellular response to oxygen containing compoundGO:19017013860.064
homeostatic processGO:00425923310.061
macromolecular complex subunit organizationGO:00439333390.060
positive regulation of gene expressionGO:00106282440.059
cellular ion homeostasisGO:00068731840.059
programmed cell deathGO:00125013920.059
divalent inorganic cation homeostasisGO:00725071650.058
cell cell signalingGO:00072673350.058
regulation of cellular protein metabolic processGO:00322682670.056
ion homeostasisGO:00508012120.056
positive regulation of phosphate metabolic processGO:00459372620.056
regulation of phosphorylationGO:00423252480.055
cellular component biogenesisGO:00440853680.055
cellular divalent inorganic cation homeostasisGO:00725031620.055
positive regulation of macromolecule biosynthetic processGO:00105572470.055
organophosphate metabolic processGO:00196373700.054
Rat
regulation of phosphate metabolic processGO:00192203490.052
brain developmentGO:00074202470.052
regulation of transcription from rna polymerase ii promoterGO:00063572340.051
ribonucleotide metabolic processGO:00092592310.051
Rat
positive regulation of response to stimulusGO:00485842850.051
positive regulation of transcription dna templatedGO:00458931970.051
nucleic acid templated transcriptionGO:00976593790.050
cell projection organizationGO:00300303020.049
neurological system processGO:00508772190.049
Mouse Rat
single organism reproductive processGO:00447022970.048
cellular response to endogenous stimulusGO:00714953770.048
positive regulation of rna biosynthetic processGO:19026801970.048
transcription from rna polymerase ii promoterGO:00063662520.047
cation homeostasisGO:00550801950.046
apoptotic processGO:00069153810.046
regulation of multicellular organismal developmentGO:20000263760.046
rna metabolic processGO:00160704060.045
regulation of rna metabolic processGO:00512523910.044
regulation of apoptotic processGO:00429813350.044
cytosolic calcium ion homeostasisGO:00514801400.044
ion transmembrane transportGO:00342203650.044
cellular cation homeostasisGO:00300031800.043
catabolic processGO:00090563510.043
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.043
regulation of secretionGO:00510462240.043
positive regulation of phosphorylationGO:00423271770.042
macromolecule localizationGO:00330362520.041
positive regulation of protein metabolic processGO:00512471780.040
positive regulation of rna metabolic processGO:00512542030.040
rna biosynthetic processGO:00327743800.040
nucleoside phosphate metabolic processGO:00067532830.040
Rat
macromolecular complex assemblyGO:00650032730.040
single organism biosynthetic processGO:00447113420.040
Mouse
cellular calcium ion homeostasisGO:00068741600.039
protein complex assemblyGO:00064612630.039
organic acid metabolic processGO:00060822920.039
cellular response to hormone stimulusGO:00328702470.039
nitrogen compound transportGO:00717052290.039
regulation of intracellular signal transductionGO:19025312180.039
g protein coupled receptor signaling pathwayGO:00071862420.039
regulation of system processGO:00440572080.038
signal transduction by phosphorylationGO:00230141440.038
positive regulation of signal transductionGO:00099671750.038
transcription dna templatedGO:00063513770.037
secretionGO:00469033070.037
carboxylic acid metabolic processGO:00197522890.037
negative regulation of nitrogen compound metabolic processGO:00511721610.037
positive regulation of cellular protein metabolic processGO:00322701670.037
neuron developmentGO:00486662860.036
regulation of rna biosynthetic processGO:20011413810.036
cellular component assemblyGO:00226073600.036
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.036
negative regulation of macromolecule metabolic processGO:00106052600.036
cellular chemical homeostasisGO:00550822470.035
positive regulation of phosphorus metabolic processGO:00105622620.035
regulation of transcription dna templatedGO:00063553740.035
organelle organizationGO:00069962660.035
nucleobase containing small molecule metabolic processGO:00550863160.035
Rat
negative regulation of nucleobase containing compound metabolic processGO:00459341530.035
regulation of ion transportGO:00432692450.035
response to peptide hormoneGO:00434342780.035
tissue developmentGO:00098882520.035
Fly
negative regulation of signalingGO:00230571570.034
nucleotide metabolic processGO:00091172790.034
Rat
neuron projection developmentGO:00311752730.034
small molecule biosynthetic processGO:00442831240.034
central nervous system developmentGO:00074173110.034
purine ribonucleotide metabolic processGO:00091502270.033
Rat
behaviorGO:00076102050.033
Mouse
cation transportGO:00068123820.033
regulation of neurogenesisGO:00507672470.032
response to peptideGO:19016522920.032
regulation of molecular functionGO:00650093980.032
amine metabolic processGO:0009308380.032
regulation of protein modification processGO:00313991940.032
anatomical structure morphogenesisGO:00096532980.032
regulation of catalytic activityGO:00507903040.032
regulation of cellular localizationGO:00603412630.031
growthGO:00400071650.031
mapk cascadeGO:00001651400.031
regulation of programmed cell deathGO:00430673410.031
regulation of protein phosphorylationGO:00019321830.030
positive regulation of intracellular signal transductionGO:19025331380.030
cellular amine metabolic processGO:0044106380.030
reproductive processGO:00224143720.030
regulation of nervous system developmentGO:00519602640.030
positive regulation of cell proliferationGO:00082842490.029
positive regulation of catalytic activityGO:00430851840.029
carbohydrate derivative metabolic processGO:19011353460.029
Rat
regulation of cellular ketone metabolic processGO:0010565270.029
positive regulation of multicellular organismal processGO:00512403870.029
oxoacid metabolic processGO:00434362900.029
ribose phosphate metabolic processGO:00196932350.028
Rat
positive regulation of developmental processGO:00510942830.028
amide transportGO:00428861050.026
cellular amino acid metabolic processGO:00065201070.026
cellular ketone metabolic processGO:0042180510.026
positive regulation of protein phosphorylationGO:00019341350.025
response to external biotic stimulusGO:00432072210.025
negative regulation of cell communicationGO:00106481580.025
regulation of cell differentiationGO:00455953200.025
cellular response to abiotic stimulusGO:0071214850.025
regulation of cell proliferationGO:00421273590.024
regulation of mapk cascadeGO:00434081160.024
intracellular transportGO:00469071850.024
protein oligomerizationGO:00512591910.024
positive regulation of protein modification processGO:00314011420.024
divalent metal ion transportGO:00708381320.024
organonitrogen compound biosynthetic processGO:19015661670.024
positive regulation of programmed cell deathGO:00430681570.023
regulation of cellular amino acid metabolic processGO:000652120.023
response to growth factorGO:00708481890.023
ribonucleoside metabolic processGO:00091191740.023
response to lipopolysaccharideGO:00324961910.023
cellular homeostasisGO:00197252520.023
negative regulation of transcription dna templatedGO:00458921160.023
calcium ion transportGO:00068161310.023
cell morphogenesis involved in neuron differentiationGO:00486671060.023
anion transportGO:00068201780.023
response to biotic stimulusGO:00096072260.022
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
divalent inorganic cation transportGO:00725111340.022
negative regulation of macromolecule biosynthetic processGO:00105581480.022
purine nucleotide metabolic processGO:00061632290.022
Rat
head developmentGO:00603222470.022
protein complex biogenesisGO:00702712630.022
establishment of protein localizationGO:00451841410.022
protein complex subunit organizationGO:00718223020.022
negative regulation of apoptotic processGO:00430661810.022
negative regulation of cell deathGO:00605482290.022
cellular response to nitrogen compoundGO:19016992100.022
response to organophosphorusGO:00466831020.021
peptidyl amino acid modificationGO:00181931260.021
inorganic ion transmembrane transportGO:00986602290.021
protein localizationGO:00081041910.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
adult locomotory behaviorGO:000834440.021
developmental growthGO:00485891000.021
regulation of neuron deathGO:19012141150.021
regulation of cellular amine metabolic processGO:003323880.021
positive regulation of transportGO:00510502450.021
forebrain developmentGO:0030900980.021
synaptic transmissionGO:00072682350.021
purine containing compound metabolic processGO:00725212530.021
Rat
multicellular organismal reproductive processGO:00486092330.020
response to nutrient levelsGO:00316673700.020
positive regulation of molecular functionGO:00440932300.020
cellular component movementGO:00069282480.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
response to extracellular stimulusGO:00099913800.020
blood circulationGO:00080151830.020
regulation of transferase activityGO:00513381230.020
small gtpase mediated signal transductionGO:0007264360.020
secretion by cellGO:00329402480.020
organophosphate biosynthetic processGO:00904071430.020
negative regulation of biosynthetic processGO:00098901680.019
Mouse
cellular nitrogen compound catabolic processGO:00442701630.019
Rat
single organism intracellular transportGO:19025821660.019
positive regulation of cellular component organizationGO:00511302000.019
cellular response to stressGO:00335542690.019
cellular catabolic processGO:00442482950.019
Rat
hormone transportGO:00099141210.019
purine nucleoside metabolic processGO:00422781690.019
cellular response to growth factor stimulusGO:00713631620.019
response to bacteriumGO:00096172000.019
response to woundingGO:00096112540.019
ribonucleotide catabolic processGO:00092611360.018
Rat
regulation of protein kinase activityGO:00458591050.018
regulation of peptide hormone secretionGO:0090276800.018
response to estradiolGO:00323551640.018
regulation of kinase activityGO:00435491170.018
regulation of membrane potentialGO:00423911100.018
protein autophosphorylationGO:0046777660.018
negative regulation of response to stimulusGO:00485851550.017
positive regulation of cell differentiationGO:00455972170.017
cell morphogenesis involved in differentiationGO:00009041190.017
cellular lipid metabolic processGO:00442552080.017
response to cytokineGO:00340972150.017
embryonic pattern specificationGO:000988010.017
chemosensory behaviorGO:000763520.017
proteolysisGO:00065081750.017
positive regulation of mapk cascadeGO:0043410920.017
muscle cell proliferationGO:0033002840.017
protein transportGO:00150311320.017
regulation of purine nucleotide metabolic processGO:19005421150.017
negative regulation of signal transductionGO:0009968830.017
peptide hormone secretionGO:0030072840.017
regulation of neuron differentiationGO:00456642080.017
nucleobase containing compound catabolic processGO:00346551520.017
Rat
positive regulation of neurogenesisGO:00507691650.016
monovalent inorganic cation transportGO:00156721720.016
negative regulation of gene expressionGO:00106291990.016
negative regulation of rna biosynthetic processGO:19026791180.016
cell morphogenesisGO:00009021420.016
nucleoside metabolic processGO:00091161790.016
circulatory system processGO:00030131830.016
negative regulation of secretion by cellGO:1903531720.016
positive regulation of transferase activityGO:0051347810.016
organic substance catabolic processGO:19015753160.016
Rat
glycosyl compound metabolic processGO:19016571820.016
regenerationGO:00310991630.016
inflammatory responseGO:00069541500.016
negative regulation of transportGO:00510511360.016
cytoplasmic transportGO:00164821150.016
circulatory system developmentGO:00723591340.016
negative regulation of cellular biosynthetic processGO:00313271610.016
Mouse
regulation of cell developmentGO:00602842630.016
single organism behaviorGO:00447081300.016
Mouse
ras protein signal transductionGO:0007265290.016
developmental process involved in reproductionGO:00030061590.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
negative regulation of programmed cell deathGO:00430691830.015
organic cyclic compound catabolic processGO:19013611750.015
Rat
cell projection morphogenesisGO:00488581230.015
eye morphogenesisGO:004859240.015
response to other organismGO:00517072200.015
purine ribonucleoside metabolic processGO:00461281680.015
positive regulation of secretionGO:00510471400.015
regulation of neuron projection developmentGO:00109751610.015
positive regulation of cellular amine metabolic processGO:003324030.015
response to carbohydrateGO:00097431830.015
neuron deathGO:00709971270.015
regulation of calcium ion transportGO:0051924770.015
cellular component morphogenesisGO:00329891550.015
response to estrogenGO:00436272320.015
nucleotide catabolic processGO:00091661390.015
Rat
single organism organelle organizationGO:19025891800.015
negative regulation of cellular protein metabolic processGO:00322691060.015
positive regulation of cell deathGO:00109421840.015
negative regulation of phosphate metabolic processGO:0045936800.015
regulation of cell projection organizationGO:00313441750.015
regulation of hormone levelsGO:00108171870.015
epithelial cell differentiationGO:0030855710.015
rhythmic processGO:00485111560.014
organonitrogen compound catabolic processGO:19015651790.014
Rat
negative regulation of rna metabolic processGO:00512531230.014
positive regulation of kinase activityGO:0033674770.014
peptide secretionGO:0002790860.014
neuron projection morphogenesisGO:00488121220.014
locomotionGO:00400112370.014
regulation of nucleotide metabolic processGO:00061401170.014
phospholipid metabolic processGO:0006644610.014
negative regulation of protein metabolic processGO:00512481140.014
carboxylic acid transportGO:00469421150.014
sequestering of calcium ionGO:005120880.014
epithelium developmentGO:0060429960.014
regulation of proteasomal protein catabolic processGO:006113640.014
regulation of insulin secretionGO:0050796650.014
nucleoside phosphate biosynthetic processGO:19012931020.014
regulation of response to stressGO:00801341260.014
cellular response to organic cyclic compoundGO:00714072020.014
regulation of growthGO:00400081050.014
axis specificationGO:000979840.014
positive regulation of nervous system developmentGO:00519621780.014
olfactory behaviorGO:004204820.014
tube developmentGO:0035295890.014
learning or memoryGO:0007611900.014
Mouse
nucleoside phosphate catabolic processGO:19012921400.014
Rat
agingGO:00075682410.014
cardiac chamber developmentGO:000320510.013
establishment of planar polarityGO:000173610.013
regulation of smooth muscle cell proliferationGO:0048660750.013
regulation of secretion by cellGO:19035302080.013
cell migrationGO:00164771970.013
salivary gland developmentGO:000743130.013
heterocycle catabolic processGO:00467001670.013
Rat
cation transmembrane transportGO:00986552630.013
dendrite developmentGO:0016358720.013
hormone secretionGO:00468791150.013
multi organism reproductive processGO:00447032620.013
peptide transportGO:0015833970.013
cardiovascular system developmentGO:00723581340.013
purine ribonucleotide catabolic processGO:00091541360.013
Rat
regulation of metal ion transportGO:00109591180.013
carbohydrate derivative biosynthetic processGO:19011371240.013
nucleotide biosynthetic processGO:0009165980.013
single organism cellular localizationGO:19025801020.013
smooth muscle cell proliferationGO:0048659770.013
positive regulation of protein kinase activityGO:0045860730.013
aromatic compound catabolic processGO:00194391680.013
Rat
centrosome organizationGO:005129710.013
reproductionGO:00000032450.013
signal releaseGO:00230611450.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
inorganic cation transmembrane transportGO:00986622020.012
maintenance of locationGO:0051235170.012
positive regulation of apoptotic processGO:00430651540.012
regulation of anatomical structure morphogenesisGO:00226031410.012
sequestering of metal ionGO:005123890.012
cellular macromolecule localizationGO:00707271220.012
single organism catabolic processGO:00447122830.012
Rat
cell cell signaling involved in cell fate commitmentGO:004516820.012
wound healingGO:00420601220.012
regulation of catabolic processGO:00098941130.012
organic acid biosynthetic processGO:0016053830.012
regulation of neuron apoptotic processGO:0043523830.012
organ morphogenesisGO:0009887750.012
peptidyl tyrosine phosphorylationGO:0018108720.012
multicellular organism growthGO:003526410.012
organic hydroxy compound metabolic processGO:19016151150.012
negative regulation of multicellular organismal processGO:00512412030.012
striated muscle tissue developmentGO:0014706580.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
cytoskeleton organizationGO:00070101110.012
vesicle mediated transportGO:00161921810.012
carboxylic acid biosynthetic processGO:0046394830.012
cell type specific apoptotic processGO:00972851340.012
neuron apoptotic processGO:0051402880.012
regulation of lipid metabolic processGO:0019216680.012
Mouse
purine nucleotide biosynthetic processGO:0006164830.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
development of primary sexual characteristicsGO:00451371070.011
olfactory learningGO:000835510.011
regulation of blood vessel sizeGO:0050880890.011
sodium ion transportGO:0006814820.011
positive regulation of cell developmentGO:00107201760.011
leukocyte cell cell adhesionGO:000715940.011
cellular protein localizationGO:00346131220.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
purine containing compound biosynthetic processGO:0072522850.011
positive regulation of neuron projection developmentGO:0010976990.011
muscle contractionGO:0006936880.011
lipid transportGO:0006869610.011
response to hydrogen peroxideGO:0042542890.011
muscle structure developmentGO:0061061870.011
regulation of defense responseGO:0031347680.011
anion transmembrane transportGO:0098656770.011
cellular response to steroid hormone stimulusGO:0071383930.011
regulation of homeostatic processGO:00328441010.011
morphogenesis of embryonic epitheliumGO:001633130.011
microtubule organizing center organizationGO:003102310.011
carbohydrate derivative catabolic processGO:19011361470.011
Rat
cell growthGO:00160491040.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
defense responseGO:00069521940.011
Mouse
glycosyl compound catabolic processGO:19016581260.011
negative regulation of cell developmentGO:0010721820.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
localization of cellGO:00516742020.011
regulation of transmembrane transportGO:00347621220.011
reactive nitrogen species metabolic processGO:200105710.011
positive regulation of neuron differentiationGO:00456661260.011
spindle organizationGO:000705120.011
retina morphogenesis in camera type eyeGO:006004210.010
response to inorganic substanceGO:00100353770.010
Rat
cell adhesionGO:00071551100.010
ribonucleotide biosynthetic processGO:0009260850.010
response to transition metal nanoparticleGO:19902671220.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
heart morphogenesisGO:000300730.010
membrane organizationGO:0061024940.010
pallium developmentGO:0021543420.010
purine nucleoside triphosphate catabolic processGO:00091461220.010
ribose phosphate biosynthetic processGO:0046390870.010
regulation of synaptic transmissionGO:00508041410.010
sensory perception of light stimulusGO:005095330.010
negative regulation of molecular functionGO:00440921330.010
regulation of hormone secretionGO:00468831060.010
guanosine containing compound metabolic processGO:1901068740.010
cell part morphogenesisGO:00329901230.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
cellular response to organonitrogen compoundGO:00714171970.010
response to molecule of bacterial originGO:00022371940.010
sodium ion transmembrane transportGO:0035725670.010
cell cycleGO:00070491010.010
response to ketoneGO:19016541820.010

Pde8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
Human
nervous system diseaseDOID:86300.066
Human
sensory system diseaseDOID:005015500.042
eye and adnexa diseaseDOID:149200.019
eye diseaseDOID:561400.019
retinal diseaseDOID:567900.016
retinal degenerationDOID:846600.016
retinitis pigmentosaDOID:1058400.016
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011