Rattus norvegicus

7 known processes

Psen2

presenilin 2

Psen2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
metal ion transportGO:00300012890.107
positive regulation of multicellular organismal processGO:00512403870.084
negative regulation of macromolecule metabolic processGO:00106052600.084
cation transportGO:00068123820.079
cellular ion homeostasisGO:00068731840.071
negative regulation of cellular metabolic processGO:00313242810.067
negative regulation of metabolic processGO:00098923310.064
cellular response to oxygen containing compoundGO:19017013860.062
cellular response to endogenous stimulusGO:00714953770.059
regulation of cellular component organizationGO:00511283680.058
chemical homeostasisGO:00488782920.058
positive regulation of cell communicationGO:00106472710.055
regulation of catalytic activityGO:00507903040.055
intracellular signal transductionGO:00355563140.053
positive regulation of signalingGO:00230562700.053
response to external biotic stimulusGO:00432072210.052
multi organism reproductive processGO:00447032620.052
regulation of multicellular organismal developmentGO:20000263760.052
organelle organizationGO:00069962660.051
regulation of signal transductionGO:00099663180.051
programmed cell deathGO:00125013920.049
regulation of ion transportGO:00432692450.049
single organism intracellular transportGO:19025821660.048
cellular chemical homeostasisGO:00550822470.047
positive regulation of response to stimulusGO:00485842850.047
response to mechanical stimulusGO:00096121340.047
oxoacid metabolic processGO:00434362900.046
response to inorganic substanceGO:00100353770.046
response to extracellular stimulusGO:00099913800.046
homeostatic processGO:00425923310.045
response to nutrient levelsGO:00316673700.044
neuron differentiationGO:00301823680.044
anion transportGO:00068201780.044
regulation of cell differentiationGO:00455953200.042
organic acid metabolic processGO:00060822920.042
defense responseGO:00069521940.042
positive regulation of nitrogen compound metabolic processGO:00511733340.042
intracellular transportGO:00469071850.042
neurological system processGO:00508772190.042
negative regulation of macromolecule biosynthetic processGO:00105581480.041
apoptotic processGO:00069153810.041
cellular homeostasisGO:00197252520.041
cellular response to hormone stimulusGO:00328702470.041
response to biotic stimulusGO:00096072260.041
ion transmembrane transportGO:00342203650.040
response to peptideGO:19016522920.040
response to lipopolysaccharideGO:00324961910.039
cellular amino acid metabolic processGO:00065201070.039
negative regulation of biosynthetic processGO:00098901680.038
positive regulation of cell differentiationGO:00455972170.038
regulation of protein metabolic processGO:00512462890.038
regulation of neurogenesisGO:00507672470.038
positive regulation of intracellular signal transductionGO:19025331380.038
response to other organismGO:00517072200.038
regulation of nervous system developmentGO:00519602640.038
transcription dna templatedGO:00063513770.037
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.037
cellular component biogenesisGO:00440853680.037
negative regulation of multicellular organismal processGO:00512412030.036
regulation of molecular functionGO:00650093980.036
carbohydrate derivative metabolic processGO:19011353460.036
regulation of cell developmentGO:00602842630.035
positive regulation of programmed cell deathGO:00430681570.035
regulation of transcription dna templatedGO:00063553740.035
regulation of cellular protein metabolic processGO:00322682670.035
positive regulation of signal transductionGO:00099671750.035
response to peptide hormoneGO:00434342780.035
regulation of neuron differentiationGO:00456642080.034
reproductive processGO:00224143720.034
cellular cation homeostasisGO:00300031800.034
rna metabolic processGO:00160704060.034
cellular response to lipidGO:00713962010.034
negative regulation of gene expressionGO:00106291990.034
response to molecule of bacterial originGO:00022371940.033
positive regulation of cellular biosynthetic processGO:00313282950.033
positive regulation of neurogenesisGO:00507691650.033
single organism organelle organizationGO:19025891800.033
positive regulation of cell proliferationGO:00082842490.033
circulatory system processGO:00030131830.033
carboxylic acid metabolic processGO:00197522890.032
protein phosphorylationGO:00064683450.032
positive regulation of nervous system developmentGO:00519621780.032
central nervous system developmentGO:00074173110.032
regulation of phosphorus metabolic processGO:00511743490.031
positive regulation of cell developmentGO:00107201760.031
cellular response to organic cyclic compoundGO:00714072020.031
cation homeostasisGO:00550801950.031
regulation of rna metabolic processGO:00512523910.031
nucleic acid templated transcriptionGO:00976593790.031
cellular response to peptide hormone stimulusGO:00713751200.030
response to metal ionGO:00100382530.030
positive regulation of molecular functionGO:00440932300.030
regulation of nucleic acid templated transcriptionGO:19035063800.030
response to cytokineGO:00340972150.030
regulation of cellular amine metabolic processGO:003323880.030
regulation of cell proliferationGO:00421273590.030
organic acid transportGO:00158491160.030
cell projection organizationGO:00300303020.030
ion homeostasisGO:00508012120.029
response to acid chemicalGO:00011012220.029
single organism biosynthetic processGO:00447113420.029
positive regulation of phosphorus metabolic processGO:00105622620.029
negative regulation of cellular biosynthetic processGO:00313271610.029
positive regulation of phosphate metabolic processGO:00459372620.029
positive regulation of biosynthetic processGO:00098913190.029
regulation of rna biosynthetic processGO:20011413810.029
negative regulation of transcription dna templatedGO:00458921160.027
regulation of apoptotic processGO:00429813350.027
positive regulation of cell deathGO:00109421840.027
cellular response to stressGO:00335542690.027
rna biosynthetic processGO:00327743800.027
response to bacteriumGO:00096172000.027
cellular response to organonitrogen compoundGO:00714171970.027
cell type specific apoptotic processGO:00972851340.026
negative regulation of cell communicationGO:00106481580.026
transmembrane transportGO:00550854120.026
cellular amine metabolic processGO:0044106380.026
regulation of cellular amino acid metabolic processGO:000652120.026
regulation of programmed cell deathGO:00430673410.026
establishment of protein localizationGO:00451841410.026
carboxylic acid transportGO:00469421150.026
regulation of intracellular signal transductionGO:19025312180.025
cellular component assemblyGO:00226073600.025
positive regulation of developmental processGO:00510942830.024
small gtpase mediated signal transductionGO:0007264360.024
agingGO:00075682410.024
mapk cascadeGO:00001651400.024
negative regulation of protein metabolic processGO:00512481140.024
response to carbohydrateGO:00097431830.024
regulation of immune system processGO:00026821230.024
vesicle mediated transportGO:00161921810.023
cellular response to nitrogen compoundGO:19016992100.023
divalent inorganic cation transportGO:00725111340.023
multicellular organismal reproductive processGO:00486092330.023
purine containing compound metabolic processGO:00725212530.023
macromolecular complex subunit organizationGO:00439333390.023
organic substance catabolic processGO:19015753160.022
macromolecule localizationGO:00330362520.022
divalent inorganic cation homeostasisGO:00725071650.022
inflammatory responseGO:00069541500.022
oxidation reduction processGO:00551143040.022
cytosolic calcium ion homeostasisGO:00514801400.022
muscle system processGO:00030121150.022
nucleoside phosphate metabolic processGO:00067532830.022
brain developmentGO:00074202470.022
cellular response to cytokine stimulusGO:00713451270.022
positive regulation of apoptotic processGO:00430651540.022
cell migrationGO:00164771970.022
regulation of phosphorylationGO:00423252480.022
response to ketoneGO:19016541820.022
reactive oxygen species metabolic processGO:0072593370.022
negative regulation of cell deathGO:00605482290.021
metal ion homeostasisGO:00550651860.021
nitrogen compound transportGO:00717052290.021
regulation of system processGO:00440572080.021
blood circulationGO:00080151830.021
organophosphate metabolic processGO:00196373700.021
amine metabolic processGO:0009308380.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
nucleobase containing small molecule metabolic processGO:00550863160.021
anatomical structure morphogenesisGO:00096532980.021
neuron deathGO:00709971270.021
regulation of membrane potentialGO:00423911100.021
organonitrogen compound biosynthetic processGO:19015661670.020
maintenance of locationGO:0051235170.020
negative regulation of developmental processGO:00510931250.020
growthGO:00400071650.020
positive regulation of transcription dna templatedGO:00458931970.020
negative regulation of apoptotic processGO:00430661810.020
reproductionGO:00000032450.020
g protein coupled receptor signaling pathwayGO:00071862420.020
single organism reproductive processGO:00447022970.020
purine nucleotide metabolic processGO:00061632290.020
nucleotide metabolic processGO:00091172790.020
single organism catabolic processGO:00447122830.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
regulation of cell projection organizationGO:00313441750.019
positive regulation of phosphorylationGO:00423271770.019
membrane organizationGO:0061024940.019
regulation of phosphate metabolic processGO:00192203490.019
response to vitaminGO:00332731310.019
actin filament based processGO:0030029860.019
negative regulation of signalingGO:00230571570.019
cellular response to biotic stimulusGO:0071216590.019
regulation of nucleotide metabolic processGO:00061401170.019
catabolic processGO:00090563510.019
negative regulation of nitrogen compound metabolic processGO:00511721610.019
protein localizationGO:00081041910.019
organic anion transportGO:00157111320.019
positive regulation of cellular amine metabolic processGO:003324030.019
cellular catabolic processGO:00442482950.019
ras protein signal transductionGO:0007265290.018
regulation of reactive oxygen species metabolic processGO:2000377260.018
positive regulation of gene expressionGO:00106282440.018
positive regulation of catalytic activityGO:00430851840.018
positive regulation of cellular protein metabolic processGO:00322701670.018
response to oxygen levelsGO:00704822650.018
ribose phosphate metabolic processGO:00196932350.018
regulation of cellular ketone metabolic processGO:0010565270.018
cytoplasmic transportGO:00164821150.018
neuron developmentGO:00486662860.018
negative regulation of programmed cell deathGO:00430691830.018
immune system processGO:00023762040.018
regulation of neuron deathGO:19012141150.018
response to hypoxiaGO:00016662310.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
response to insulinGO:00328681330.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
cell cell signalingGO:00072673350.018
tissue developmentGO:00098882520.018
neuron projection developmentGO:00311752730.018
inorganic ion transmembrane transportGO:00986602290.018
organic hydroxy compound transportGO:0015850770.018
multicellular organismal signalingGO:0035637440.018
signal transduction by phosphorylationGO:00230141440.018
regulation of protein modification processGO:00313991940.018
reactive nitrogen species metabolic processGO:200105710.017
regulation of cell migrationGO:00303341280.017
positive regulation of transportGO:00510502450.017
positive regulation of neuron differentiationGO:00456661260.017
positive regulation of rna metabolic processGO:00512542030.017
transmission of nerve impulseGO:0019226420.017
head developmentGO:00603222470.017
divalent metal ion transportGO:00708381320.017
behaviorGO:00076102050.017
sexual reproductionGO:00199531480.017
multicellular organism reproductionGO:00325042330.017
cellular response to abiotic stimulusGO:0071214850.017
cellular response to external stimulusGO:00714961180.017
positive regulation of rna biosynthetic processGO:19026801970.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
negative regulation of rna biosynthetic processGO:19026791180.017
monovalent inorganic cation transportGO:00156721720.017
lipid metabolic processGO:00066292830.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
regulation of protein phosphorylationGO:00019321830.017
gastrulationGO:000736920.017
gamete generationGO:00072761240.016
regulation of response to stressGO:00801341260.016
negative regulation of cell proliferationGO:00082851190.016
cellular calcium ion homeostasisGO:00068741600.016
response to oxidative stressGO:00069791860.016
nucleoside phosphate biosynthetic processGO:19012931020.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
positive regulation of protein phosphorylationGO:00019341350.016
positive regulation of cellular component organizationGO:00511302000.016
protein transportGO:00150311320.016
regulation of cell motilityGO:20001451310.016
regulation of neuron projection developmentGO:00109751610.016
regulation of secretion by cellGO:19035302080.016
regulation of purine nucleotide metabolic processGO:19005421150.016
localization of cellGO:00516742020.016
cyclic nucleotide biosynthetic processGO:0009190630.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
negative regulation of rna metabolic processGO:00512531230.015
regulation of canonical wnt signaling pathwayGO:006082840.015
anion transmembrane transportGO:0098656770.015
regulation of metal ion transportGO:00109591180.015
cellular component movementGO:00069282480.015
response to ethanolGO:00454711620.015
regulation of cellular localizationGO:00603412630.015
cellular ketone metabolic processGO:0042180510.015
response to growth factorGO:00708481890.015
negative regulation of cellular protein metabolic processGO:00322691060.015
glial cell differentiationGO:0010001650.015
cytokine productionGO:0001816610.015
response to estrogenGO:00436272320.015
regulation of blood pressureGO:0008217830.015
action potentialGO:0001508540.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
calcium ion transportGO:00068161310.015
ribonucleotide metabolic processGO:00092592310.015
nucleotide biosynthetic processGO:0009165980.015
kidney developmentGO:0001822670.014
organophosphate biosynthetic processGO:00904071430.014
multicellular organism growthGO:003526410.014
chemosensory behaviorGO:000763520.014
single organism cellular localizationGO:19025801020.014
developmental process involved in reproductionGO:00030061590.014
regulation of neuron apoptotic processGO:0043523830.014
regulation of catabolic processGO:00098941130.014
nucleoside metabolic processGO:00091161790.014
response to transition metal nanoparticleGO:19902671220.014
cellular response to acid chemicalGO:0071229750.014
embryonic pattern specificationGO:000988010.014
cellular response to peptideGO:19016531330.014
cardiac chamber developmentGO:000320510.014
protein localization to organelleGO:0033365570.014
cellular metal ion homeostasisGO:00068751720.014
muscle contractionGO:0006936880.014
negative regulation of cellular component organizationGO:0051129830.014
regulation of synaptic transmissionGO:00508041410.014
glycosyl compound metabolic processGO:19016571820.014
negative regulation of cell differentiationGO:0045596990.014
positive regulation of protein metabolic processGO:00512471780.014
salivary gland developmentGO:000743130.014
positive regulation of ion transportGO:0043270940.014
renal system developmentGO:0072001670.014
response to decreased oxygen levelsGO:00362932370.013
positive regulation of cell projection organizationGO:00313461110.013
cellular response to tumor necrosis factorGO:0071356460.013
single organism behaviorGO:00447081300.013
regulation of blood circulationGO:19035221100.013
response to glucocorticoidGO:00513842230.013
cellular protein localizationGO:00346131220.013
purine ribonucleotide metabolic processGO:00091502270.013
response to woundingGO:00096112540.013
regenerationGO:00310991630.013
nucleobase containing compound catabolic processGO:00346551520.013
regulation of hydrolase activityGO:00513361430.013
axis specificationGO:000979840.013
locomotionGO:00400112370.013
amide transportGO:00428861050.013
gland developmentGO:00487321550.013
positive regulation of locomotionGO:00400171020.013
response to nutrientGO:00075842480.013
reactive oxygen species biosynthetic processGO:190340980.013
calcium ion homeostasisGO:00550741620.013
response to hexoseGO:00097461440.013
organonitrogen compound catabolic processGO:19015651790.013
peptide metabolic processGO:0006518320.013
negative regulation of cell developmentGO:0010721820.013
positive regulation of neuron projection developmentGO:0010976990.013
regulation of nucleotide catabolic processGO:0030811650.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.013
cellular response to growth factor stimulusGO:00713631620.013
development of primary sexual characteristicsGO:00451371070.013
negative regulation of response to stimulusGO:00485851550.013
response to tumor necrosis factorGO:0034612560.013
positive regulation of protein modification processGO:00314011420.013
response to corticosteroidGO:00319602350.012
cell growthGO:00160491040.012
regulation of cellular component movementGO:00512701500.012
intracellular protein transportGO:0006886790.012
cellular response to insulin stimulusGO:0032869810.012
regulation of hormone levelsGO:00108171870.012
negative regulation of transportGO:00510511360.012
positive regulation of hydrolase activityGO:0051345860.012
negative regulation of neurogenesisGO:0050768780.012
positive regulation of secretion by cellGO:19035321280.012
heart morphogenesisGO:000300730.012
secretion by cellGO:00329402480.012
regulation of growthGO:00400081050.012
protein complex assemblyGO:00064612630.012
regulation of defense responseGO:0031347680.012
response to radiationGO:00093141370.012
actin mediated cell contractionGO:0070252120.012
neuron apoptotic processGO:0051402880.012
response to glucoseGO:00097491360.012
learning or memoryGO:0007611900.012
synaptic transmissionGO:00072682350.012
neuronal action potentialGO:0019228350.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
secretionGO:00469033070.012
protein complex biogenesisGO:00702712630.012
regulation of anatomical structure morphogenesisGO:00226031410.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
regulation of locomotionGO:00400121480.012
positive regulation of mapk cascadeGO:0043410920.012
lipid storageGO:001991510.012
negative regulation of innate immune responseGO:004582440.012
cell motilityGO:00488702020.012
positive regulation of reactive oxygen species metabolic processGO:2000379160.012
transcription from rna polymerase ii promoterGO:00063662520.012
negative regulation of signal transductionGO:0009968830.012
regulation of protein kinase activityGO:00458591050.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
negative regulation of kidney developmentGO:009018520.012
organic cyclic compound catabolic processGO:19013611750.012
purine containing compound biosynthetic processGO:0072522850.012
lipid transportGO:0006869610.012
positive regulation of purine nucleotide metabolic processGO:1900544910.011
cytokine mediated signaling pathwayGO:0019221430.011
cell activationGO:0001775970.011
cation transmembrane transportGO:00986552630.011
purine nucleotide catabolic processGO:00061951360.011
response to fatty acidGO:0070542650.011
inorganic cation transmembrane transportGO:00986622020.011
sequestering of calcium ionGO:005120880.011
carbohydrate homeostasisGO:0033500750.011
negative regulation of molecular functionGO:00440921330.011
male gamete generationGO:0048232990.011
protein oligomerizationGO:00512591910.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.011
multi multicellular organism processGO:00447061380.011
carbohydrate derivative biosynthetic processGO:19011371240.011
purine nucleoside metabolic processGO:00422781690.011
response to estradiolGO:00323551640.011
rhythmic processGO:00485111560.011
cellular response to molecule of bacterial originGO:0071219560.011
macromolecular complex assemblyGO:00650032730.011
response to toxic substanceGO:00096361330.011
cellular response to lipopolysaccharideGO:0071222550.011
regulation of calcium ion transportGO:0051924770.011
spermatogenesisGO:0007283990.011
chromosome segregationGO:000705920.011
eye morphogenesisGO:004859240.010
negative regulation of neuron differentiationGO:0045665620.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
cellular amide metabolic processGO:0043603440.010
gliogenesisGO:0042063930.010
response to alkaloidGO:00432791320.010
steroid metabolic processGO:0008202730.010
sensory perceptionGO:00076001010.010
reproductive system developmentGO:00614581280.010
regulation of transferase activityGO:00513381230.010
purine ribonucleoside metabolic processGO:00461281680.010
regulation of cell growthGO:0001558850.010
nucleoside phosphate catabolic processGO:19012921400.010
circulatory system developmentGO:00723591340.010
response to purine containing compoundGO:00140741260.010
heterocycle catabolic processGO:00467001670.010
developmental growthGO:00485891000.010
cytoskeleton dependent cytokinesisGO:006164020.010
regulation of cell morphogenesisGO:0022604770.010
peptide transportGO:0015833970.010
ribonucleotide biosynthetic processGO:0009260850.010
regulation of secretionGO:00510462240.010
cellular response to alcoholGO:0097306870.010
response to monosaccharideGO:00342841590.010

Psen2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.033
inherited metabolic disorderDOID:65500.033
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
musculoskeletal system diseaseDOID:1700.015
cardiovascular system diseaseDOID:128700.011