Rattus norvegicus

37 known processes

Psen1

presenilin 1

Psen1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of signal transductionGO:00099671750.382
regulation of cell proliferationGO:00421273590.336
immune system processGO:00023762040.320
response to cytokineGO:00340972150.289
mapk cascadeGO:00001651400.275
regulation of cellular protein metabolic processGO:00322682670.251
anatomical structure morphogenesisGO:00096532980.241
carboxylic acid metabolic processGO:00197522890.232
endocytosisGO:0006897840.229
growthGO:00400071650.223
agingGO:00075682410.223
regulation of protein metabolic processGO:00512462890.215
positive regulation of multicellular organismal processGO:00512403870.207
cell motilityGO:00488702020.204
cellular catabolic processGO:00442482950.196
cellular response to endogenous stimulusGO:00714953770.195
rhythmic processGO:00485111560.190
single organism intracellular transportGO:19025821660.178
positive regulation of cell communicationGO:00106472710.176
positive regulation of response to stimulusGO:00485842850.175
response to peptide hormoneGO:00434342780.157
wound healingGO:00420601220.150
regulation of intracellular signal transductionGO:19025312180.149
organic substance catabolic processGO:19015753160.149
transcription dna templatedGO:00063513770.147
localization of cellGO:00516742020.147
intracellular transportGO:00469071850.146
digestive tract developmentGO:0048565390.138
response to woundingGO:00096112540.137
cellular response to oxygen containing compoundGO:19017013860.135
intracellular signal transductionGO:00355563140.134
positive regulation of protein metabolic processGO:00512471780.133
catabolic processGO:00090563510.129
organic acid metabolic processGO:00060822920.127
response to peptideGO:19016522920.126
carbohydrate derivative metabolic processGO:19011353460.124
positive regulation of signalingGO:00230562700.123
regulation of phosphorus metabolic processGO:00511743490.122
cellular component assemblyGO:00226073600.111
leukocyte activationGO:0045321760.111
regulation of multicellular organismal developmentGO:20000263760.111
positive regulation of cellular protein metabolic processGO:00322701670.109
single organism catabolic processGO:00447122830.108
secretionGO:00469033070.106
cellular amino acid metabolic processGO:00065201070.105
rna biosynthetic processGO:00327743800.105
regulation of cellular component organizationGO:00511283680.103
reproductive processGO:00224143720.103
nucleic acid templated transcriptionGO:00976593790.103
regulation of catalytic activityGO:00507903040.100
negative regulation of apoptotic processGO:00430661810.100
positive regulation of nitrogen compound metabolic processGO:00511733340.100
positive regulation of immune system processGO:0002684900.099
regulation of cellular localizationGO:00603412630.099
response to extracellular stimulusGO:00099913800.097
negative regulation of metabolic processGO:00098923310.095
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.094
negative regulation of developmental processGO:00510931250.093
protein phosphorylationGO:00064683450.091
regulation of response to stressGO:00801341260.091
positive regulation of molecular functionGO:00440932300.091
immune responseGO:00069551040.091
response to other organismGO:00517072200.090
negative regulation of nitrogen compound metabolic processGO:00511721610.087
cellular response to hormone stimulusGO:00328702470.086
negative regulation of cellular metabolic processGO:00313242810.086
signal transduction by phosphorylationGO:00230141440.085
cellular component movementGO:00069282480.085
positive regulation of secretionGO:00510471400.084
programmed cell deathGO:00125013920.082
regulation of apoptotic processGO:00429813350.082
regulation of transcription dna templatedGO:00063553740.080
digestive system developmentGO:0055123410.080
positive regulation of transportGO:00510502450.080
regulation of immune system processGO:00026821230.078
protein complex subunit organizationGO:00718223020.078
cellular component biogenesisGO:00440853680.076
bmp signaling pathwayGO:003050940.076
positive regulation of nucleobase containing compound metabolic processGO:00459353190.075
rna metabolic processGO:00160704060.074
positive regulation of biosynthetic processGO:00098913190.073
nucleobase containing small molecule metabolic processGO:00550863160.072
neurological system processGO:00508772190.072
enzyme linked receptor protein signaling pathwayGO:00071671160.072
oxoacid metabolic processGO:00434362900.072
negative regulation of cell differentiationGO:0045596990.072
response to external biotic stimulusGO:00432072210.071
negative regulation of cell proliferationGO:00082851190.071
positive regulation of rna biosynthetic processGO:19026801970.071
protein maturationGO:0051604680.070
positive regulation of macromolecule biosynthetic processGO:00105572470.069
cellular amine metabolic processGO:0044106380.069
behaviorGO:00076102050.069
regulation of cell differentiationGO:00455953200.069
renal system developmentGO:0072001670.069
cell projection organizationGO:00300303020.069
single organism reproductive processGO:00447022970.067
organelle organizationGO:00069962660.066
response to corticosteroidGO:00319602350.066
positive regulation of cellular biosynthetic processGO:00313282950.066
lens development in camera type eyeGO:0002088130.066
multicellular organism growthGO:003526410.066
central nervous system developmentGO:00074173110.065
cognitionGO:0050890920.065
organophosphate metabolic processGO:00196373700.065
positive regulation of rna metabolic processGO:00512542030.065
regulation of cell motilityGO:20001451310.064
positive regulation of gene expressionGO:00106282440.064
regulation of rna metabolic processGO:00512523910.063
regulation of secretionGO:00510462240.063
tissue developmentGO:00098882520.063
response to nutrient levelsGO:00316673700.062
defense responseGO:00069521940.062
chemical homeostasisGO:00488782920.062
neuron differentiationGO:00301823680.061
secretion by cellGO:00329402480.061
regulation of phosphate metabolic processGO:00192203490.061
positive regulation of cytokine secretionGO:005071590.061
head developmentGO:00603222470.060
cellular response to peptide hormone stimulusGO:00713751200.060
neuron projection developmentGO:00311752730.059
positive regulation of phosphate metabolic processGO:00459372620.058
cell cell signalingGO:00072673350.058
regulation of protein modification processGO:00313991940.058
organophosphate catabolic processGO:00464341480.058
transcription from rna polymerase ii promoterGO:00063662520.057
biological adhesionGO:00226101100.057
negative regulation of response to stimulusGO:00485851550.057
response to nicotineGO:0035094510.057
protein localizationGO:00081041910.057
response to ethanolGO:00454711620.056
transforming growth factor beta receptor signaling pathwayGO:0007179180.056
regulation of nucleic acid templated transcriptionGO:19035063800.056
response to temperature stimulusGO:0009266940.056
lymphocyte activationGO:0046649430.055
multi organism reproductive processGO:00447032620.055
sex differentiationGO:00075481130.055
regulation of response to external stimulusGO:00321011060.055
neuron projection morphogenesisGO:00488121220.055
negative regulation of multicellular organismal processGO:00512412030.054
positive regulation of protein kinase activityGO:0045860730.054
connective tissue developmentGO:0061448330.053
positive regulation of phosphorus metabolic processGO:00105622620.053
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.053
immune effector processGO:0002252530.053
male sex differentiationGO:0046661640.053
cell adhesionGO:00071551100.053
locomotionGO:00400112370.052
purine nucleotide metabolic processGO:00061632290.052
negative regulation of signalingGO:00230571570.052
regulation of phosphorylationGO:00423252480.052
homeostatic processGO:00425923310.051
positive regulation of cell proliferationGO:00082842490.051
blood circulationGO:00080151830.051
neuron deathGO:00709971270.051
muscle structure developmentGO:0061061870.051
regulation of protein transportGO:0051223680.051
response to hypoxiaGO:00016662310.050
purine ribonucleotide metabolic processGO:00091502270.050
regulation of signal transductionGO:00099663180.050
gland developmentGO:00487321550.050
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729610.050
vesicle mediated transportGO:00161921810.050
protein complex assemblyGO:00064612630.049
positive regulation of cell differentiationGO:00455972170.049
ribose phosphate metabolic processGO:00196932350.049
blood vessel developmentGO:0001568690.049
regulation of transcription from rna polymerase ii promoterGO:00063572340.049
negative regulation of macromolecule metabolic processGO:00106052600.049
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010060.048
regulation of cellular component movementGO:00512701500.048
macromolecule localizationGO:00330362520.047
ion homeostasisGO:00508012120.047
apoptotic processGO:00069153810.047
amine metabolic processGO:0009308380.046
ribonucleotide catabolic processGO:00092611360.046
regulation of cell migrationGO:00303341280.046
positive regulation of cellular component movementGO:00512721020.046
positive regulation of nucleic acid templated transcriptionGO:19035081970.046
cell morphogenesisGO:00009021420.045
regulation of secretion by cellGO:19035302080.045
response to biotic stimulusGO:00096072260.045
cell growthGO:00160491040.045
single organism behaviorGO:00447081300.044
neuron developmentGO:00486662860.044
response to organophosphorusGO:00466831020.044
regulation of protein localizationGO:0032880810.043
organ morphogenesisGO:0009887750.043
regulation of rna biosynthetic processGO:20011413810.043
immune system developmentGO:0002520410.043
cell morphogenesis involved in neuron differentiationGO:00486671060.043
response to monosaccharideGO:00342841590.043
female gonad developmentGO:0008585530.043
negative regulation of cell deathGO:00605482290.043
positive regulation of protein modification processGO:00314011420.043
cellular response to stressGO:00335542690.042
positive regulation of phosphorylationGO:00423271770.042
purine containing compound metabolic processGO:00725212530.042
negative regulation of gene expressionGO:00106291990.042
organophosphate biosynthetic processGO:00904071430.042
development of primary sexual characteristicsGO:00451371070.042
multicellular organismal reproductive processGO:00486092330.041
cellular component morphogenesisGO:00329891550.041
positive regulation of cytokine productionGO:0001819420.041
positive regulation of secretion by cellGO:19035321280.041
proteolysisGO:00065081750.041
regulation of growthGO:00400081050.041
synaptic transmissionGO:00072682350.041
nitrogen compound transportGO:00717052290.040
gonad developmentGO:00084061040.040
regulation of response to woundingGO:1903034690.040
response to amino acidGO:0043200750.040
cellular ketone metabolic processGO:0042180510.040
cellular response to lipidGO:00713962010.040
response to toxic substanceGO:00096361330.040
cellular response to nitrogen compoundGO:19016992100.039
protein processingGO:0016485680.039
nucleotide metabolic processGO:00091172790.039
response to transforming growth factor betaGO:0071559460.039
macromolecule catabolic processGO:0009057580.038
regulation of hormone levelsGO:00108171870.038
positive regulation of transcription dna templatedGO:00458931970.038
response to oxidative stressGO:00069791860.038
response to decreased oxygen levelsGO:00362932370.038
positive regulation of cell motilityGO:2000147970.038
regulation of molecular functionGO:00650093980.038
response to nutrientGO:00075842480.038
embryonic cranial skeleton morphogenesisGO:004870120.037
establishment of protein localizationGO:00451841410.037
purine nucleoside monophosphate metabolic processGO:0009126840.037
sexual reproductionGO:00199531480.037
positive regulation of developmental processGO:00510942830.036
ribonucleotide metabolic processGO:00092592310.036
cellular lipid metabolic processGO:00442552080.036
negative regulation of cell communicationGO:00106481580.036
regulation of hormone secretionGO:00468831060.036
protein complex biogenesisGO:00702712630.035
response to reactive oxygen speciesGO:00003021200.035
macromolecular complex subunit organizationGO:00439333390.035
positive regulation of nucleocytoplasmic transportGO:0046824170.035
purine nucleotide catabolic processGO:00061951360.035
regulation of anatomical structure morphogenesisGO:00226031410.035
regulation of defense responseGO:0031347680.034
cytoskeleton organizationGO:00070101110.034
regulation of cellular ketone metabolic processGO:0010565270.034
cell migrationGO:00164771970.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.034
chemosensory behaviorGO:000763520.034
t cell activationGO:0042110290.034
ribonucleoside metabolic processGO:00091191740.034
brain developmentGO:00074202470.034
development of primary female sexual characteristicsGO:0046545560.033
cell type specific apoptotic processGO:00972851340.033
response to insulinGO:00328681330.033
response to heatGO:0009408600.033
embryonic skeletal system developmentGO:004870630.033
ras protein signal transductionGO:0007265290.032
nucleoside phosphate metabolic processGO:00067532830.032
regulation of cellular amino acid metabolic processGO:000652120.032
response to glucoseGO:00097491360.032
response to alkaloidGO:00432791320.032
regulation of programmed cell deathGO:00430673410.032
macromolecular complex assemblyGO:00650032730.032
reproductive structure developmentGO:00486081280.032
ovulation cycleGO:0042698670.032
regulation of cell adhesionGO:0030155520.032
regulation of mapk cascadeGO:00434081160.032
positive regulation of cellular amino acid metabolic processGO:004576410.031
cellular protein localizationGO:00346131220.031
negative regulation of growthGO:0045926370.031
learningGO:0007612330.031
multicellular organism reproductionGO:00325042330.031
response to purine containing compoundGO:00140741260.030
regulation of cell growthGO:0001558850.030
positive regulation of mesenchymal cell proliferationGO:000205340.030
ovulation cycle processGO:0022602500.030
response to mechanical stimulusGO:00096121340.030
regulation of intracellular transportGO:0032386650.030
response to lipopolysaccharideGO:00324961910.029
regulation of epithelial cell differentiationGO:0030856120.029
reproductionGO:00000032450.029
regulation of nervous system developmentGO:00519602640.029
heterocycle catabolic processGO:00467001670.029
response to carbohydrateGO:00097431830.029
regulation of mesenchymal cell proliferationGO:001046440.029
positive regulation of cellular component organizationGO:00511302000.029
purine ribonucleoside triphosphate metabolic processGO:00092051400.029
regulation of homotypic cell cell adhesionGO:003411040.028
positive regulation of catalytic activityGO:00430851840.028
actin filament based processGO:0030029860.028
cellular response to peptideGO:19016531330.028
lipid metabolic processGO:00066292830.028
cell activationGO:0001775970.028
hepaticobiliary system developmentGO:0061008900.028
negative regulation of programmed cell deathGO:00430691830.028
dna metabolic processGO:0006259960.028
response to growth factorGO:00708481890.028
activation of protein kinase activityGO:0032147470.028
regulation of catabolic processGO:00098941130.027
response to molecule of bacterial originGO:00022371940.027
negative regulation of phosphate metabolic processGO:0045936800.027
forebrain developmentGO:0030900980.027
inflammatory responseGO:00069541500.027
reproductive system developmentGO:00614581280.027
cell cycleGO:00070491010.027
positive regulation of protein transportGO:0051222410.027
regulation of cellular amine metabolic processGO:003323880.027
regulation of system processGO:00440572080.027
regulation of tube sizeGO:0035150890.026
response to hydrogen peroxideGO:0042542890.026
regulation of protein kinase activityGO:00458591050.026
glial cell apoptotic processGO:003434980.026
positive regulation of locomotionGO:00400171020.026
urogenital system developmentGO:0001655780.026
memoryGO:0007613540.026
organic cyclic compound catabolic processGO:19013611750.026
regulation of wound healingGO:0061041140.026
small gtpase mediated signal transductionGO:0007264360.026
positive regulation of nervous system developmentGO:00519621780.026
response to hexoseGO:00097461440.026
positive regulation of cell migrationGO:0030335960.026
negative regulation of transcription dna templatedGO:00458921160.026
olfactory learningGO:000835510.025
cardiovascular system developmentGO:00723581340.025
regulation of kinase activityGO:00435491170.025
cellular nitrogen compound catabolic processGO:00442701630.025
hemopoiesisGO:0030097340.025
response to ammonium ionGO:0060359710.025
generation of precursor metabolites and energyGO:0006091620.025
response to estrogenGO:00436272320.025
regulation of anatomical structure sizeGO:00900661350.025
g protein coupled receptor signaling pathwayGO:00071862420.025
regulation of body fluid levelsGO:0050878900.025
regulation of synaptic transmissionGO:00508041410.025
response to oxygen levelsGO:00704822650.025
neuron apoptotic processGO:0051402880.025
neural crest cell differentiationGO:001403320.024
hormone transportGO:00099141210.024
eye morphogenesisGO:004859240.024
developmental growthGO:00485891000.024
response to radiationGO:00093141370.024
protein transportGO:00150311320.024
response to uv cGO:001022520.024
negative regulation of neuron apoptotic processGO:0043524450.024
negative regulation of phosphorus metabolic processGO:0010563800.024
cell morphogenesis involved in differentiationGO:00009041190.024
hematopoietic progenitor cell differentiationGO:000224420.024
peptidyl tyrosine phosphorylationGO:0018108720.024
purine nucleoside triphosphate metabolic processGO:00091441410.024
positive regulation of cell developmentGO:00107201760.024
regulation of cellular component biogenesisGO:0044087860.024
nucleoside triphosphate catabolic processGO:00091431230.024
cellular metal ion homeostasisGO:00068751720.024
negative regulation of cellular protein metabolic processGO:00322691060.024
single organism biosynthetic processGO:00447113420.023
divalent inorganic cation transportGO:00725111340.023
learning or memoryGO:0007611900.023
single organism carbohydrate metabolic processGO:00447231180.023
negative regulation of protein metabolic processGO:00512481140.023
cellular chemical homeostasisGO:00550822470.023
circulatory system developmentGO:00723591340.023
positive regulation of intracellular signal transductionGO:19025331380.023
protein targetingGO:0006605610.023
regulation of establishment of protein localizationGO:0070201690.023
regulation of cytokine productionGO:0001817560.023
carbohydrate derivative biosynthetic processGO:19011371240.022
positive regulation of intracellular transportGO:0032388390.022
response to ketoneGO:19016541820.022
regulation of transforming growth factor beta3 productionGO:003291020.022
negative regulation of organ growthGO:004662130.022
gastrulationGO:000736920.022
dendrite morphogenesisGO:0048813430.022
response to cocaineGO:0042220390.022
sensory organ developmentGO:0007423740.022
positive regulation of kinase activityGO:0033674770.022
regulation of neurogenesisGO:00507672470.022
negative regulation of cell cycle phase transitionGO:190198840.022
reactive oxygen species metabolic processGO:0072593370.022
negative regulation of mitotic cell cycle phase transitionGO:190199130.021
nucleoside triphosphate metabolic processGO:00091411440.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
single organism organelle organizationGO:19025891800.021
epithelium developmentGO:0060429960.021
gamete generationGO:00072761240.021
cytokine productionGO:0001816610.021
regulation of locomotionGO:00400121480.021
erythrocyte differentiationGO:003021810.021
positive regulation of mapk cascadeGO:0043410920.020
cellular homeostasisGO:00197252520.020
regulation of cellular catabolic processGO:00313291010.020
cellular response to organonitrogen compoundGO:00714171970.020
response to vitaminGO:00332731310.020
eye developmentGO:0001654500.020
ribonucleoside monophosphate metabolic processGO:0009161880.020
anatomical structure formation involved in morphogenesisGO:0048646830.020
spindle organizationGO:000705120.020
hematopoietic or lymphoid organ developmentGO:0048534360.020
cellular response to insulin stimulusGO:0032869810.019
regulation of protein phosphorylationGO:00019321830.019
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.019
negative regulation of rna metabolic processGO:00512531230.019
regulation of cell cycleGO:0051726730.019
positive regulation of transferase activityGO:0051347810.019
female sex differentiationGO:0046660590.019
negative regulation of rna biosynthetic processGO:19026791180.019
purine nucleoside catabolic processGO:00061521240.019
regulation of transferase activityGO:00513381230.019
response to inorganic substanceGO:00100353770.019
mullerian duct regressionGO:000188020.019
cellular protein complex assemblyGO:0043623440.019
positive regulation of response to woundingGO:1903036340.019
cartilage developmentGO:0051216220.019
protein autophosphorylationGO:0046777660.019
positive regulation of biomineral tissue developmentGO:007016940.019
positive regulation of cellular amine metabolic processGO:003324030.019
carbohydrate metabolic processGO:00059751300.019
regulation of apoptotic signaling pathwayGO:2001233130.019
transforming growth factor beta receptor complex assemblyGO:000718120.019
exocytosisGO:0006887600.018
response to campGO:0051591910.018
interleukin 1 beta secretionGO:005070230.018
aromatic compound catabolic processGO:00194391680.018
olfactory behaviorGO:004204820.018
peptidyl tyrosine modificationGO:0018212720.018
cellular macromolecular complex assemblyGO:0034622580.018
response to transition metal nanoparticleGO:19902671220.018
ribonucleotide biosynthetic processGO:0009260850.018
regulation of membrane potentialGO:00423911100.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.018
protein import into nucleusGO:0006606350.018
positive regulation of skeletal muscle tissue regenerationGO:004341510.018
cell cycle checkpointGO:000007520.018
regulation of inflammatory responseGO:0050727480.018
membrane organizationGO:0061024940.018
organic anion transportGO:00157111320.018
purine ribonucleotide catabolic processGO:00091541360.018
response to bacteriumGO:00096172000.018
negative regulation of kidney developmentGO:009018520.018
cellular response to external stimulusGO:00714961180.018
kidney developmentGO:0001822670.018
developmental process involved in reproductionGO:00030061590.017
hormone secretionGO:00468791150.017
positive regulation of neurogenesisGO:00507691650.017
alpha beta t cell differentiationGO:004663220.017
establishment of protein localization to organelleGO:0072594440.017
regulation of smoothened signaling pathwayGO:000858920.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.017
transformation of host cell by virusGO:001908740.017
neural crest cell developmentGO:001403220.017
nucleocytoplasmic transportGO:0006913480.017
anion transportGO:00068201780.017
regulation of nucleotide metabolic processGO:00061401170.017
divalent metal ion transportGO:00708381320.017
cytoplasmic transportGO:00164821150.017
ribonucleoside triphosphate metabolic processGO:00091991410.017
glycosyl compound metabolic processGO:19016571820.017
vasoconstrictionGO:0042310540.017
cellular response to organic cyclic compoundGO:00714072020.017
peptidyl amino acid modificationGO:00181931260.017
transforming growth factor beta3 productionGO:003290720.017
negative regulation of pancreatic stellate cell proliferationGO:200023010.017
lipid storageGO:001991510.017
positive regulation of transforming growth factor beta3 productionGO:003291620.017
protein heterooligomerizationGO:0051291890.017
carbohydrate derivative catabolic processGO:19011361470.017
response to acid chemicalGO:00011012220.017
cell projection morphogenesisGO:00488581230.016
cation homeostasisGO:00550801950.016
embryonic skeletal system morphogenesisGO:004870430.016
regulation of blood vessel sizeGO:0050880890.016
nucleoside metabolic processGO:00091161790.016
organonitrogen compound catabolic processGO:19015651790.016
signal releaseGO:00230611450.016
embryo developmentGO:0009790490.016
myeloid leukocyte activationGO:0002274360.016
steroid metabolic processGO:0008202730.016
vascular process in circulatory systemGO:0003018960.016
mitotic spindle organizationGO:000705220.016
positive regulation of defense responseGO:0031349370.016
lipid localizationGO:0010876620.016
regulation of endocytosisGO:0030100420.016
mammary gland epithelium developmentGO:006118010.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126910.016
actin cytoskeleton organizationGO:0030036730.016
regulation of ossificationGO:0030278320.016
anterior posterior pattern specificationGO:000995210.016
hormone metabolic processGO:0042445690.016
maintenance of locationGO:0051235170.015
calcium ion transportGO:00068161310.015
cellular amide metabolic processGO:0043603440.015
skeletal system morphogenesisGO:0048705120.015
neuron projection guidanceGO:0097485240.015

Psen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
sensory system diseaseDOID:005015500.021
disease of anatomical entityDOID:700.021