Rattus norvegicus

41 known processes

Pfn2

profilin 2

Pfn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component organizationGO:00511283680.068
organic substance catabolic processGO:19015753160.056
intracellular signal transductionGO:00355563140.048
apoptotic processGO:00069153810.048
regulation of cellular protein metabolic processGO:00322682670.041
regulation of molecular functionGO:00650093980.040
protein modification by small protein conjugation or removalGO:0070647350.039
nucleic acid templated transcriptionGO:00976593790.038
Rat
regulation of transcription dna templatedGO:00063553740.038
Rat
regulation of ion transportGO:00432692450.037
cell projection organizationGO:00300303020.037
regulation of protein metabolic processGO:00512462890.036
central nervous system developmentGO:00074173110.036
regulation of catalytic activityGO:00507903040.035
transcription dna templatedGO:00063513770.034
Rat
head developmentGO:00603222470.033
multi organism reproductive processGO:00447032620.033
regulation of cellular localizationGO:00603412630.032
regulation of rna biosynthetic processGO:20011413810.032
Rat
positive regulation of signal transductionGO:00099671750.032
cation transportGO:00068123820.032
chemical homeostasisGO:00488782920.031
protein complex assemblyGO:00064612630.031
response to woundingGO:00096112540.030
carbohydrate derivative metabolic processGO:19011353460.029
neuron differentiationGO:00301823680.029
brain developmentGO:00074202470.028
negative regulation of response to stimulusGO:00485851550.028
regulation of signal transductionGO:00099663180.027
cellular catabolic processGO:00442482950.027
regulation of rna metabolic processGO:00512523910.026
Rat
response to nutrient levelsGO:00316673700.026
multicellular organism reproductionGO:00325042330.026
purine containing compound metabolic processGO:00725212530.025
anatomical structure morphogenesisGO:00096532980.025
positive regulation of ion transportGO:0043270940.025
negative regulation of metabolic processGO:00098923310.025
regulation of cell projection organizationGO:00313441750.025
regulation of apoptotic processGO:00429813350.024
regulation of programmed cell deathGO:00430673410.024
macromolecule localizationGO:00330362520.024
response to peptideGO:19016522920.024
catabolic processGO:00090563510.024
transmembrane transportGO:00550854120.024
regulation of protein modification processGO:00313991940.024
response to other organismGO:00517072200.023
negative regulation of cellular metabolic processGO:00313242810.023
regenerationGO:00310991630.023
multicellular organismal reproductive processGO:00486092330.023
negative regulation of neuron differentiationGO:0045665620.023
neuron projection developmentGO:00311752730.023
positive regulation of nervous system developmentGO:00519621780.022
response to biotic stimulusGO:00096072260.022
protein complex biogenesisGO:00702712630.022
rna biosynthetic processGO:00327743800.022
Rat
regulation of phosphorus metabolic processGO:00511743490.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
Rat
organelle organizationGO:00069962660.022
negative regulation of signalingGO:00230571570.021
cellular amine metabolic processGO:0044106380.021
regulation of secretionGO:00510462240.021
negative regulation of multicellular organismal processGO:00512412030.021
regulation of proteasomal protein catabolic processGO:006113640.021
cellular component biogenesisGO:00440853680.021
rna metabolic processGO:00160704060.021
Rat
single organism catabolic processGO:00447122830.020
chromosome segregationGO:000705920.020
single organism organelle organizationGO:19025891800.020
regulation of phosphate metabolic processGO:00192203490.020
response to peptide hormoneGO:00434342780.020
regulation of nervous system developmentGO:00519602640.020
positive regulation of transcription dna templatedGO:00458931970.020
Rat
response to external biotic stimulusGO:00432072210.020
regulation of cell growthGO:0001558850.020
protein phosphorylationGO:00064683450.019
cellular response to stressGO:00335542690.019
positive regulation of intracellular signal transductionGO:19025331380.019
organophosphate metabolic processGO:00196373700.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
Rat
organic acid metabolic processGO:00060822920.019
positive regulation of cellular component organizationGO:00511302000.019
Rat
regulation of intracellular signal transductionGO:19025312180.019
regulation of cell differentiationGO:00455953200.019
programmed cell deathGO:00125013920.019
single organism reproductive processGO:00447022970.018
negative regulation of macromolecule metabolic processGO:00106052600.018
negative regulation of cell communicationGO:00106481580.018
cell cycleGO:00070491010.018
homeostatic processGO:00425923310.018
organonitrogen compound catabolic processGO:19015651790.018
negative regulation of mitotic cell cycle phase transitionGO:190199130.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
Rat
agingGO:00075682410.018
positive regulation of biosynthetic processGO:00098913190.018
Rat
protein catabolic processGO:0030163300.018
cellular amino acid metabolic processGO:00065201070.017
response to insulinGO:00328681330.017
ribonucleotide metabolic processGO:00092592310.017
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
Rat
regulation of hormone levelsGO:00108171870.017
response to molecule of bacterial originGO:00022371940.017
negative regulation of molecular functionGO:00440921330.017
single organism biosynthetic processGO:00447113420.017
protein tetramerizationGO:0051262380.017
oxoacid metabolic processGO:00434362900.017
cellular response to oxygen containing compoundGO:19017013860.017
cell cycle checkpointGO:000007520.016
ion homeostasisGO:00508012120.016
transcription from rna polymerase ii promoterGO:00063662520.016
Rat
organonitrogen compound biosynthetic processGO:19015661670.016
cell growthGO:00160491040.016
response to nutrientGO:00075842480.016
cellular component assemblyGO:00226073600.016
regulation of cell developmentGO:00602842630.016
positive regulation of cell developmentGO:00107201760.016
response to decreased oxygen levelsGO:00362932370.016
negative regulation of gene expressionGO:00106291990.016
nucleoside phosphate biosynthetic processGO:19012931020.016
nucleobase containing small molecule metabolic processGO:00550863160.016
alpha amino acid metabolic processGO:1901605710.016
positive regulation of transportGO:00510502450.016
amine metabolic processGO:0009308380.015
purine nucleotide metabolic processGO:00061632290.015
positive regulation of developmental processGO:00510942830.015
purine containing compound biosynthetic processGO:0072522850.015
synaptic transmissionGO:00072682350.015
response to extracellular stimulusGO:00099913800.015
regulation of neuron projection developmentGO:00109751610.015
response to bacteriumGO:00096172000.015
regulation of cellular component biogenesisGO:0044087860.015
regulation of metal ion transportGO:00109591180.015
cellular homeostasisGO:00197252520.015
growthGO:00400071650.015
positive regulation of cell differentiationGO:00455972170.014
organophosphate biosynthetic processGO:00904071430.014
organ regenerationGO:00311001010.014
defense responseGO:00069521940.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
Rat
regulation of cellular amino acid metabolic processGO:000652120.014
cellular response to peptideGO:19016531330.014
positive regulation of protein metabolic processGO:00512471780.014
response to carbohydrateGO:00097431830.014
response to radiationGO:00093141370.014
positive regulation of protein phosphorylationGO:00019341350.014
nucleotide biosynthetic processGO:0009165980.014
response to oxygen levelsGO:00704822650.014
positive regulation of signalingGO:00230562700.014
proteolysisGO:00065081750.014
behaviorGO:00076102050.014
regulation of body fluid levelsGO:0050878900.014
organic acid biosynthetic processGO:0016053830.014
positive regulation of phosphorus metabolic processGO:00105622620.014
positive regulation of secretionGO:00510471400.014
positive regulation of multicellular organismal processGO:00512403870.013
positive regulation of cellular biosynthetic processGO:00313282950.013
Rat
cellular response to hormone stimulusGO:00328702470.013
regulation of multicellular organismal developmentGO:20000263760.013
regulation of protein phosphorylationGO:00019321830.013
small molecule biosynthetic processGO:00442831240.013
positive regulation of rna biosynthetic processGO:19026801970.013
Rat
secretionGO:00469033070.013
regulation of cellular amine metabolic processGO:003323880.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
Rat
regulation of cell migrationGO:00303341280.013
ribonucleoside metabolic processGO:00091191740.013
protein homooligomerizationGO:0051260910.013
regulation of neuron differentiationGO:00456642080.013
metal ion transportGO:00300012890.013
nucleotide metabolic processGO:00091172790.013
cellular component morphogenesisGO:00329891550.013
positive regulation of response to stimulusGO:00485842850.013
macromolecular complex assemblyGO:00650032730.013
nucleoside metabolic processGO:00091161790.013
nucleoside monophosphate metabolic processGO:0009123930.013
sensory perception of painGO:0019233730.013
carboxylic acid metabolic processGO:00197522890.013
response to hypoxiaGO:00016662310.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
positive regulation of cell proliferationGO:00082842490.013
response to mechanical stimulusGO:00096121340.013
regulation of neurogenesisGO:00507672470.013
positive regulation of phosphate metabolic processGO:00459372620.012
neuron developmentGO:00486662860.012
response to hexoseGO:00097461440.012
sister chromatid segregationGO:000081910.012
regulation of anatomical structure morphogenesisGO:00226031410.012
cellular response to nitrogen compoundGO:19016992100.012
nucleotide catabolic processGO:00091661390.012
regulation of system processGO:00440572080.012
negative regulation of transcription dna templatedGO:00458921160.012
negative regulation of apoptotic processGO:00430661810.012
cellular response to endogenous stimulusGO:00714953770.012
secretion by cellGO:00329402480.012
negative regulation of cellular protein metabolic processGO:00322691060.012
protein oligomerizationGO:00512591910.012
response to lipopolysaccharideGO:00324961910.012
negative regulation of protein metabolic processGO:00512481140.012
protein localizationGO:00081041910.012
positive regulation of rna metabolic processGO:00512542030.012
Rat
purine ribonucleotide metabolic processGO:00091502270.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
regulation of growthGO:00400081050.012
macromolecule catabolic processGO:0009057580.012
macromolecular complex subunit organizationGO:00439333390.012
positive regulation of phosphorylationGO:00423271770.012
cellular response to growth factor stimulusGO:00713631620.012
Rat
regulation of cell proliferationGO:00421273590.012
response to growth factorGO:00708481890.012
Rat
negative regulation of transportGO:00510511360.012
cellular response to organonitrogen compoundGO:00714171970.012
ion transmembrane transportGO:00342203650.012
response to starvationGO:0042594590.011
heart morphogenesisGO:000300730.011
negative regulation of programmed cell deathGO:00430691830.011
neurological system processGO:00508772190.011
ribose phosphate metabolic processGO:00196932350.011
nucleobase biosynthetic processGO:004611220.011
positive regulation of cellular amine metabolic processGO:003324030.011
positive regulation of cell communicationGO:00106472710.011
reproductionGO:00000032450.011
regulation of transferase activityGO:00513381230.011
sensory perceptionGO:00076001010.011
endomembrane system organizationGO:0010256480.011
negative regulation of growthGO:0045926370.011
response to glucoseGO:00097491360.011
negative regulation of catalytic activityGO:00430861030.011
multi multicellular organism processGO:00447061380.011
protein complex subunit organizationGO:00718223020.011
regulation of response to external stimulusGO:00321011060.011
protein modification by small protein conjugationGO:0032446310.011
muscle structure developmentGO:0061061870.011
response to axon injuryGO:0048678590.011
amp metabolic processGO:004603380.011
ubiquitin dependent protein catabolic processGO:0006511140.011
cell motilityGO:00488702020.011
cytoplasmic transportGO:00164821150.011
regulation of hydrolase activityGO:00513361430.011
nitrogen compound transportGO:00717052290.011
negative regulation of nitrogen compound metabolic processGO:00511721610.010
regulation of locomotionGO:00400121480.010
localization of cellGO:00516742020.010
spermatogenesisGO:0007283990.010
positive regulation of cellular protein metabolic processGO:00322701670.010
reproductive processGO:00224143720.010
regulation of canonical wnt signaling pathwayGO:006082840.010
positive regulation of neuron differentiationGO:00456661260.010
regulation of cellular ketone metabolic processGO:0010565270.010
cardiac chamber developmentGO:000320510.010
cellular response to peptide hormone stimulusGO:00713751200.010
purine nucleoside monophosphate metabolic processGO:0009126840.010
metal ion homeostasisGO:00550651860.010

Pfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
musculoskeletal system diseaseDOID:1700.017
muscle tissue diseaseDOID:6600.017
myopathyDOID:42300.017
muscular diseaseDOID:008000000.017
muscular dystrophyDOID:988400.017
sensory system diseaseDOID:005015500.012