Rattus norvegicus

22 known processes

Lipa

lipase A, lysosomal acid, cholesterol esterase

(Aliases: Chole,LAL,Chole2,Lip1)

Lipa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.392
organic acid metabolic processGO:00060822920.336
oxoacid metabolic processGO:00434362900.230
single organism biosynthetic processGO:00447113420.192
organic substance catabolic processGO:19015753160.147
cellular component assemblyGO:00226073600.134
catabolic processGO:00090563510.128
response to inorganic substanceGO:00100353770.112
cellular catabolic processGO:00442482950.107
protein complex biogenesisGO:00702712630.105
response to nutrient levelsGO:00316673700.102
response to peptideGO:19016522920.099
lipid metabolic processGO:00066292830.098
cellular amino acid metabolic processGO:00065201070.096
macromolecular complex subunit organizationGO:00439333390.087
single organism catabolic processGO:00447122830.082
cellular lipid metabolic processGO:00442552080.081
cellular component biogenesisGO:00440853680.078
oxidation reduction processGO:00551143040.078
Rat
macromolecular complex assemblyGO:00650032730.075
cellular amide metabolic processGO:0043603440.075
cellular modified amino acid metabolic processGO:0006575610.073
small molecule biosynthetic processGO:00442831240.068
protein oligomerizationGO:00512591910.067
carbohydrate metabolic processGO:00059751300.066
protein complex assemblyGO:00064612630.066
small molecule catabolic processGO:0044282590.065
lipid oxidationGO:0034440300.060
response to acid chemicalGO:00011012220.060
programmed cell deathGO:00125013920.059
homeostatic processGO:00425923310.059
Fly
positive regulation of developmental processGO:00510942830.057
regulation of multicellular organismal developmentGO:20000263760.056
secretionGO:00469033070.056
protein complex subunit organizationGO:00718223020.056
organic hydroxy compound metabolic processGO:19016151150.056
carbohydrate derivative metabolic processGO:19011353460.055
reproductive processGO:00224143720.055
organelle organizationGO:00069962660.054
response to extracellular stimulusGO:00099913800.054
response to corticosteroidGO:00319602350.053
organic acid biosynthetic processGO:0016053830.053
response to peptide hormoneGO:00434342780.053
carboxylic acid biosynthetic processGO:0046394830.053
positive regulation of nitrogen compound metabolic processGO:00511733340.052
cellular ketone metabolic processGO:0042180510.052
cellular response to oxygen containing compoundGO:19017013860.052
regulation of cell proliferationGO:00421273590.052
cellular response to endogenous stimulusGO:00714953770.052
organophosphate metabolic processGO:00196373700.051
nitrogen compound transportGO:00717052290.051
regulation of cellular ketone metabolic processGO:0010565270.051
monocarboxylic acid metabolic processGO:00327871520.050
ion homeostasisGO:00508012120.050
regulation of cellular component organizationGO:00511283680.050
apoptotic processGO:00069153810.050
single organism carbohydrate metabolic processGO:00447231180.050
response to metal ionGO:00100382530.049
nucleobase containing small molecule metabolic processGO:00550863160.049
regenerationGO:00310991630.048
cellular response to hormone stimulusGO:00328702470.048
regulation of secretionGO:00510462240.048
fatty acid beta oxidationGO:0006635220.048
response to glucocorticoidGO:00513842230.047
chemical homeostasisGO:00488782920.047
Fly
positive regulation of cell communicationGO:00106472710.047
positive regulation of biosynthetic processGO:00098913190.046
transmembrane transportGO:00550854120.046
cellular amine metabolic processGO:0044106380.046
fatty acid oxidationGO:0019395290.046
reproductionGO:00000032450.045
Fly
amine metabolic processGO:0009308380.045
regulation of apoptotic processGO:00429813350.045
regulation of programmed cell deathGO:00430673410.044
carboxylic acid catabolic processGO:0046395490.044
regulation of cellular amine metabolic processGO:003323880.044
response to oxidative stressGO:00069791860.044
anion transportGO:00068201780.043
response to decreased oxygen levelsGO:00362932370.043
response to estrogenGO:00436272320.042
intracellular signal transductionGO:00355563140.042
lipid biosynthetic processGO:00086101280.042
metal ion transportGO:00300012890.041
organic acid catabolic processGO:0016054490.041
cation transportGO:00068123820.041
anatomical structure morphogenesisGO:00096532980.040
Fly
response to estradiolGO:00323551640.040
brain developmentGO:00074202470.040
cellular response to peptide hormone stimulusGO:00713751200.040
cellular response to stressGO:00335542690.040
cellular response to nitrogen compoundGO:19016992100.040
multicellular organism reproductionGO:00325042330.040
Fly
regulation of hormone levelsGO:00108171870.040
protein phosphorylationGO:00064683450.039
regulation of signal transductionGO:00099663180.039
coenzyme metabolic processGO:0006732860.039
positive regulation of cell deathGO:00109421840.038
response to mechanical stimulusGO:00096121340.038
ion transmembrane transportGO:00342203650.038
positive regulation of phosphate metabolic processGO:00459372620.038
regulation of system processGO:00440572080.038
fatty acid metabolic processGO:0006631990.038
cellular response to organonitrogen compoundGO:00714171970.038
positive regulation of multicellular organismal processGO:00512403870.038
response to oxygen levelsGO:00704822650.037
positive regulation of cellular biosynthetic processGO:00313282950.037
monocarboxylic acid catabolic processGO:0072329280.037
regulation of molecular functionGO:00650093980.036
cation homeostasisGO:00550801950.036
organonitrogen compound biosynthetic processGO:19015661670.036
regulation of secretion by cellGO:19035302080.035
regulation of ion transportGO:00432692450.035
membrane organizationGO:0061024940.035
neurological system processGO:00508772190.035
organophosphate biosynthetic processGO:00904071430.035
multicellular organismal reproductive processGO:00486092330.034
nucleotide metabolic processGO:00091172790.034
protein homooligomerizationGO:0051260910.034
response to hypoxiaGO:00016662310.033
single organism intracellular transportGO:19025821660.033
secretion by cellGO:00329402480.032
regulation of phosphorus metabolic processGO:00511743490.032
positive regulation of cell differentiationGO:00455972170.032
single organism organelle organizationGO:19025891800.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
monovalent inorganic cation transportGO:00156721720.031
regulation of cell differentiationGO:00455953200.031
central nervous system developmentGO:00074173110.031
response to nutrientGO:00075842480.030
localization of cellGO:00516742020.030
positive regulation of cellular amine metabolic processGO:003324030.030
positive regulation of phosphorus metabolic processGO:00105622620.030
cell cell signalingGO:00072673350.030
blood circulationGO:00080151830.030
regulation of protein phosphorylationGO:00019321830.030
intracellular transportGO:00469071850.030
regulation of nervous system developmentGO:00519602640.030
response to ethanolGO:00454711620.030
response to growth factorGO:00708481890.029
neuron projection developmentGO:00311752730.029
Fly
response to carbohydrateGO:00097431830.029
carboxylic acid transportGO:00469421150.029
metal ion homeostasisGO:00550651860.029
positive regulation of response to stimulusGO:00485842850.029
regulation of cellular amino acid metabolic processGO:000652120.029
regulation of protein modification processGO:00313991940.028
negative regulation of multicellular organismal processGO:00512412030.028
organic acid transportGO:00158491160.028
lipid modificationGO:0030258520.028
cellular lipid catabolic processGO:0044242370.028
regulation of phosphate metabolic processGO:00192203490.028
negative regulation of response to stimulusGO:00485851550.027
positive regulation of apoptotic processGO:00430651540.027
purine nucleoside monophosphate metabolic processGO:0009126840.027
cellular response to external stimulusGO:00714961180.027
multi organism reproductive processGO:00447032620.027
response to insulinGO:00328681330.027
transcription dna templatedGO:00063513770.027
negative regulation of programmed cell deathGO:00430691830.027
negative regulation of cell deathGO:00605482290.026
regulation of intracellular signal transductionGO:19025312180.026
cation transmembrane transportGO:00986552630.026
cellular response to peptideGO:19016531330.026
circulatory system processGO:00030131830.026
locomotionGO:00400112370.026
fatty acid catabolic processGO:0009062260.026
immune system processGO:00023762040.026
negative regulation of signalingGO:00230571570.026
cellular carbohydrate metabolic processGO:0044262720.026
positive regulation of cellular component organizationGO:00511302000.026
lipid catabolic processGO:0016042460.026
cellular response to lipidGO:00713962010.026
positive regulation of cell developmentGO:00107201760.025
organonitrogen compound catabolic processGO:19015651790.025
single organism reproductive processGO:00447022970.025
peptide metabolic processGO:0006518320.025
alpha amino acid metabolic processGO:1901605710.025
regulation of phosphorylationGO:00423252480.025
positive regulation of signalingGO:00230562700.025
sulfur compound metabolic processGO:0006790700.024
nucleoside phosphate metabolic processGO:00067532830.024
negative regulation of cellular component organizationGO:0051129830.024
cellular component movementGO:00069282480.024
synaptic transmissionGO:00072682350.024
agingGO:00075682410.024
tissue developmentGO:00098882520.024
regulation of neuron differentiationGO:00456642080.024
cofactor metabolic processGO:0051186950.023
single organism membrane organizationGO:0044802740.023
response to toxic substanceGO:00096361330.023
cellular homeostasisGO:00197252520.023
positive regulation of transportGO:00510502450.023
growthGO:00400071650.023
reproductive structure developmentGO:00486081280.023
regulation of neuron projection developmentGO:00109751610.023
positive regulation of cell proliferationGO:00082842490.022
purine ribonucleotide metabolic processGO:00091502270.022
negative regulation of transportGO:00510511360.022
regulation of transcription dna templatedGO:00063553740.022
positive regulation of rna metabolic processGO:00512542030.022
purine ribonucleoside monophosphate metabolic processGO:0009167840.022
epithelium developmentGO:0060429960.022
alcohol metabolic processGO:0006066770.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
cellular nitrogen compound catabolic processGO:00442701630.022
response to external biotic stimulusGO:00432072210.022
regulation of cell developmentGO:00602842630.022
alpha amino acid biosynthetic processGO:1901607230.022
cellular glucan metabolic processGO:0006073230.022
behaviorGO:00076102050.022
ribonucleotide metabolic processGO:00092592310.022
multi multicellular organism processGO:00447061380.022
reproductive system developmentGO:00614581280.022
positive regulation of programmed cell deathGO:00430681570.022
macromolecule localizationGO:00330362520.022
response to bacteriumGO:00096172000.021
positive regulation of phosphorylationGO:00423271770.021
regulation of neurogenesisGO:00507672470.021
regulation of protein metabolic processGO:00512462890.021
response to other organismGO:00517072200.021
cell type specific apoptotic processGO:00972851340.021
ribonucleoside metabolic processGO:00091191740.021
regulation of rna biosynthetic processGO:20011413810.021
organophosphate catabolic processGO:00464341480.021
nucleoside phosphate biosynthetic processGO:19012931020.020
purine containing compound metabolic processGO:00725212530.020
regulation of membrane potentialGO:00423911100.020
positive regulation of gene expressionGO:00106282440.020
positive regulation of lipid catabolic processGO:005099640.020
neuron differentiationGO:00301823680.020
Fly
response to reactive oxygen speciesGO:00003021200.020
cell projection organizationGO:00300303020.020
Fly
response to vitaminGO:00332731310.020
organic cyclic compound catabolic processGO:19013611750.020
g protein coupled receptor signaling pathwayGO:00071862420.020
neuron developmentGO:00486662860.020
Fly
negative regulation of metabolic processGO:00098923310.020
response to ketoneGO:19016541820.020
regulation of cellular localizationGO:00603412630.020
regulation of cell projection organizationGO:00313441750.020
negative regulation of cellular metabolic processGO:00313242810.020
regulation of lipid metabolic processGO:0019216680.019
head developmentGO:00603222470.019
response to molecule of bacterial originGO:00022371940.019
developmental process involved in reproductionGO:00030061590.019
cellular response to organic cyclic compoundGO:00714072020.019
positive regulation of intracellular signal transductionGO:19025331380.019
calcium ion homeostasisGO:00550741620.019
carbohydrate derivative catabolic processGO:19011361470.018
positive regulation of nervous system developmentGO:00519621780.018
regulation of organelle organizationGO:0033043800.018
nucleoside metabolic processGO:00091161790.018
negative regulation of cell communicationGO:00106481580.018
cognitionGO:0050890920.018
cellular calcium ion homeostasisGO:00068741600.018
peptidyl amino acid modificationGO:00181931260.018
cellular chemical homeostasisGO:00550822470.018
monocarboxylic acid biosynthetic processGO:0072330480.018
regulation of anatomical structure sizeGO:00900661350.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
gonad developmentGO:00084061040.018
cellular cation homeostasisGO:00300031800.018
development of primary sexual characteristicsGO:00451371070.018
cellular ion homeostasisGO:00068731840.018
generation of precursor metabolites and energyGO:0006091620.018
response to amino acidGO:0043200750.018
defense responseGO:00069521940.018
mapk cascadeGO:00001651400.018
purine nucleotide metabolic processGO:00061632290.018
proteolysisGO:00065081750.018
response to hexoseGO:00097461440.018
steroid metabolic processGO:0008202730.018
amide transportGO:00428861050.017
inorganic cation transmembrane transportGO:00986622020.017
cellular macromolecule localizationGO:00707271220.017
regulation of lipid biosynthetic processGO:0046890380.017
positive regulation of molecular functionGO:00440932300.017
cellular component morphogenesisGO:00329891550.017
Fly
signal releaseGO:00230611450.017
purine nucleoside metabolic processGO:00422781690.017
organic anion transportGO:00157111320.017
female pregnancyGO:00075651220.017
negative regulation of apoptotic processGO:00430661810.017
response to purine containing compoundGO:00140741260.017
response to lipopolysaccharideGO:00324961910.017
inorganic ion transmembrane transportGO:00986602290.017
protein heterooligomerizationGO:0051291890.017
urogenital system developmentGO:0001655780.017
positive regulation of cell projection organizationGO:00313461110.017
divalent inorganic cation homeostasisGO:00725071650.017
negative regulation of macromolecule metabolic processGO:00106052600.017
positive regulation of protein phosphorylationGO:00019341350.016
rna biosynthetic processGO:00327743800.016
positive regulation of signal transductionGO:00099671750.016
response to woundingGO:00096112540.016
dephosphorylationGO:0016311980.016
response to starvationGO:0042594590.016
cellular response to abiotic stimulusGO:0071214850.016
positive regulation of transcription dna templatedGO:00458931970.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
macromolecule catabolic processGO:0009057580.016
learning or memoryGO:0007611900.016
single organism cellular localizationGO:19025801020.016
cellular metal ion homeostasisGO:00068751720.016
negative regulation of molecular functionGO:00440921330.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
regulation of anatomical structure morphogenesisGO:00226031410.016
forebrain developmentGO:0030900980.016
cell motilityGO:00488702020.015
single organism behaviorGO:00447081300.015
nucleobase containing compound catabolic processGO:00346551520.015
regulation of body fluid levelsGO:0050878900.015
developmental growthGO:00485891000.015
cytosolic calcium ion homeostasisGO:00514801400.015
negative regulation of secretionGO:0051048820.015
synaptic growth at neuromuscular junctionGO:005112410.015
negative regulation of cell proliferationGO:00082851190.015
response to monosaccharideGO:00342841590.015
nucleic acid templated transcriptionGO:00976593790.015
glycerolipid metabolic processGO:0046486670.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
response to retinoic acidGO:0032526630.015
regulation of blood circulationGO:19035221100.015
transmission of nerve impulseGO:0019226420.015
regulation of cellular component movementGO:00512701500.015
regulation of cell migrationGO:00303341280.015
glutathione metabolic processGO:0006749150.015
regulation of homeostatic processGO:00328441010.015
ribose phosphate metabolic processGO:00196932350.015
liver developmentGO:0001889900.014
glutamine family amino acid biosynthetic processGO:000908420.014
hepaticobiliary system developmentGO:0061008900.014
cellular amino acid biosynthetic processGO:0008652320.014
positive regulation of mapk cascadeGO:0043410920.014
hormone secretionGO:00468791150.014
glycosyl compound metabolic processGO:19016571820.014
glycogen metabolic processGO:0005977230.014
heterocycle catabolic processGO:00467001670.014
protein localization to membraneGO:0072657360.014
aromatic compound catabolic processGO:00194391680.014
carbohydrate derivative biosynthetic processGO:19011371240.014
organic hydroxy compound transportGO:0015850770.014
rhythmic processGO:00485111560.014
nucleotide biosynthetic processGO:0009165980.014
reactive oxygen species metabolic processGO:0072593370.014
purine containing compound catabolic processGO:00725231380.014
multicellular organismal signalingGO:0035637440.014
response to alkaloidGO:00432791320.014
energy derivation by oxidation of organic compoundsGO:0015980460.014
regulation of heart contractionGO:0008016480.014
small gtpase mediated signal transductionGO:0007264360.014
positive regulation of neurogenesisGO:00507691650.014
heart contractionGO:0060047570.014
gland developmentGO:00487321550.014
positive regulation of secretion by cellGO:19035321280.014
cellular response to oxidative stressGO:0034599760.014
neuron neuron synaptic transmissionGO:0007270600.014
ribonucleoside catabolic processGO:00424541260.013
neuron deathGO:00709971270.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
exocytosisGO:0006887600.013
cytoplasmic transportGO:00164821150.013
protein homotetramerizationGO:0051289250.013
ras protein signal transductionGO:0007265290.013
regulation of synaptic transmissionGO:00508041410.013
dicarboxylic acid metabolic processGO:0043648420.013
Rat
response to organophosphorusGO:00466831020.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
muscle system processGO:00030121150.013
response to transition metal nanoparticleGO:19902671220.013
vesicle mediated transportGO:00161921810.013
regulation of catalytic activityGO:00507903040.013
sexual reproductionGO:00199531480.013
positive regulation of catalytic activityGO:00430851840.013
nucleoside monophosphate metabolic processGO:0009123930.013
cellular response to extracellular stimulusGO:0031668730.013
regulation of cellular component biogenesisGO:0044087860.013
cardiac conductionGO:006133720.013
wound healingGO:00420601220.013
regulation of cellular protein metabolic processGO:00322682670.013
rna metabolic processGO:00160704060.013
cell migrationGO:00164771970.013
regulation of locomotionGO:00400121480.013
signal transduction by phosphorylationGO:00230141440.013
transcription from rna polymerase ii promoterGO:00063662520.013
positive regulation of ion transportGO:0043270940.013
axis specificationGO:000979840.013
cellular response to growth factor stimulusGO:00713631620.013
protein localizationGO:00081041910.013
sex differentiationGO:00075481130.013
cellular response to insulin stimulusGO:0032869810.013
response to cytokineGO:00340972150.013
positive regulation of protein metabolic processGO:00512471780.013
regulation of reactive oxygen species biosynthetic processGO:190342650.012
positive regulation of neuron differentiationGO:00456661260.012
neuronal action potentialGO:0019228350.012
cell morphogenesis involved in differentiationGO:00009041190.012
regulation of blood vessel sizeGO:0050880890.012
regulation of anion transportGO:0044070430.012
hormone transportGO:00099141210.012
cellular protein localizationGO:00346131220.012
purine containing compound biosynthetic processGO:0072522850.012
cellular response to steroid hormone stimulusGO:0071383930.012
regulation of peptide transportGO:0090087870.012
positive regulation of organelle organizationGO:0010638480.012
response to temperature stimulusGO:0009266940.012
regulation of hydrolase activityGO:00513361430.012
regulation of response to external stimulusGO:00321011060.012
negative regulation of cell differentiationGO:0045596990.012
negative regulation of signal transductionGO:0009968830.012
response to glucoseGO:00097491360.012
response to biotic stimulusGO:00096072260.012
peptidyl tyrosine phosphorylationGO:0018108720.012
vascular process in circulatory systemGO:0003018960.012
adult locomotory behaviorGO:000834440.012
purine ribonucleoside metabolic processGO:00461281680.012
peptide secretionGO:0002790860.012
regulation of immune responseGO:0050776550.012
sequestering of calcium ionGO:005120880.012
glycosyl compound catabolic processGO:19016581260.012
regulation of fatty acid metabolic processGO:0019217180.012
glucan metabolic processGO:0044042230.012
multicellular organism growthGO:003526410.012
hexose metabolic processGO:0019318580.012
positive regulation of cell migrationGO:0030335960.012
cellular response to acid chemicalGO:0071229750.012
sensory perceptionGO:00076001010.012
response to campGO:0051591910.012
positive regulation of rna biosynthetic processGO:19026801970.012
response to radiationGO:00093141370.012
cellular response to oxygen levelsGO:0071453600.012
regulation of vesicle mediated transportGO:0060627810.012
tube developmentGO:0035295890.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of cell motilityGO:2000147970.012
endomembrane system organizationGO:0010256480.011
positive regulation of locomotionGO:00400171020.011
positive regulation of neuron projection developmentGO:0010976990.011
gamete generationGO:00072761240.011
kidney developmentGO:0001822670.011
regulation of smooth muscle cell proliferationGO:0048660750.011
regulation of neuron deathGO:19012141150.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
response to hydrogen peroxideGO:0042542890.011
cell morphogenesisGO:00009021420.011
Fly
regulation of cell motilityGO:20001451310.011
circulatory system developmentGO:00723591340.011
positive regulation of cellular component movementGO:00512721020.011
negative regulation of cell developmentGO:0010721820.011
embryonic pattern specificationGO:000988010.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
immune responseGO:00069551040.011
acetyl coa metabolic processGO:0006084170.011
chemosensory behaviorGO:000763520.011
regulation of metal ion transportGO:00109591180.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
purine nucleotide biosynthetic processGO:0006164830.011
actin filament based processGO:0030029860.011
negative regulation of neurogenesisGO:0050768780.011
negative regulation of nervous system developmentGO:0051961790.011
muscle contractionGO:0006936880.011
cellular response to reactive oxygen speciesGO:0034614550.011
fatty acid biosynthetic processGO:0006633330.011
nucleotide catabolic processGO:00091661390.011
organ regenerationGO:00311001010.011
cellular response to mechanical stimulusGO:0071260480.011
purine ribonucleoside catabolic processGO:00461301240.011
lipid transportGO:0006869610.011
positive regulation of fatty acid beta oxidationGO:003200040.011
glutamine family amino acid metabolic processGO:0009064150.010
divalent inorganic cation transportGO:00725111340.010
positive regulation of secretionGO:00510471400.010
phospholipid metabolic processGO:0006644610.010
multicellular organismal homeostasisGO:0048871490.010
regulation of muscle system processGO:0090257790.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.010
monosaccharide metabolic processGO:0005996610.010
cellular polysaccharide metabolic processGO:0044264230.010
potassium ion transportGO:0006813970.010
cellular macromolecular complex assemblyGO:0034622580.010
lipid localizationGO:0010876620.010
regulation of rna metabolic processGO:00512523910.010
hormone metabolic processGO:0042445690.010
energy reserve metabolic processGO:0006112250.010
reactive nitrogen species metabolic processGO:200105710.010
nucleoside phosphate catabolic processGO:19012921400.010
peptide transportGO:0015833970.010
negative regulation of secretion by cellGO:1903531720.010

Lipa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.020
central nervous system diseaseDOID:33100.015
musculoskeletal system diseaseDOID:1700.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011