Rattus norvegicus

0 known processes

Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

(Aliases: RGD1563028)

Appl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.058
carboxylic acid metabolic processGO:00197522890.052
organic acid metabolic processGO:00060822920.048
oxoacid metabolic processGO:00434362900.047
cell projection organizationGO:00300303020.046
positive regulation of multicellular organismal processGO:00512403870.045
intracellular signal transductionGO:00355563140.042
positive regulation of neuron projection developmentGO:0010976990.042
cellular amino acid metabolic processGO:00065201070.040
regulation of phosphate metabolic processGO:00192203490.039
protein complex biogenesisGO:00702712630.038
amine metabolic processGO:0009308380.038
small gtpase mediated signal transductionGO:0007264360.037
positive regulation of developmental processGO:00510942830.037
regulation of phosphorus metabolic processGO:00511743490.036
regulation of cellular component organizationGO:00511283680.035
protein complex assemblyGO:00064612630.034
regulation of phosphorylationGO:00423252480.034
neuron projection developmentGO:00311752730.034
lipid metabolic processGO:00066292830.033
carbohydrate derivative metabolic processGO:19011353460.033
regulation of neuron projection developmentGO:00109751610.033
regulation of cellular localizationGO:00603412630.033
ribose phosphate metabolic processGO:00196932350.032
cellular amine metabolic processGO:0044106380.032
positive regulation of cellular component organizationGO:00511302000.032
ras protein signal transductionGO:0007265290.030
cellular response to stressGO:00335542690.030
macromolecular complex assemblyGO:00650032730.029
neuron developmentGO:00486662860.029
nucleobase containing small molecule metabolic processGO:00550863160.029
positive regulation of intracellular signal transductionGO:19025331380.028
purine containing compound metabolic processGO:00725212530.028
positive regulation of cellular amine metabolic processGO:003324030.028
regulation of multicellular organismal developmentGO:20000263760.027
catabolic processGO:00090563510.027
glycosyl compound metabolic processGO:19016571820.027
positive regulation of phosphorus metabolic processGO:00105622620.027
regulation of molecular functionGO:00650093980.027
regulation of cellular amine metabolic processGO:003323880.026
organophosphate metabolic processGO:00196373700.026
regulation of canonical wnt signaling pathwayGO:006082840.026
positive regulation of phosphate metabolic processGO:00459372620.026
regulation of nervous system developmentGO:00519602640.026
protein oligomerizationGO:00512591910.026
negative regulation of cellular metabolic processGO:00313242810.026
cellular catabolic processGO:00442482950.025
regulation of neuron differentiationGO:00456642080.025
macromolecule localizationGO:00330362520.025
cellular component biogenesisGO:00440853680.025
positive regulation of cellular protein metabolic processGO:00322701670.025
regulation of catalytic activityGO:00507903040.024
protein complex subunit organizationGO:00718223020.024
purine containing compound catabolic processGO:00725231380.024
positive regulation of cell developmentGO:00107201760.024
positive regulation of neurogenesisGO:00507691650.024
organonitrogen compound catabolic processGO:19015651790.024
positive regulation of cellular amino acid metabolic processGO:004576410.024
rna metabolic processGO:00160704060.024
regulation of cell projection organizationGO:00313441750.024
positive regulation of nervous system developmentGO:00519621780.024
regulation of cell developmentGO:00602842630.024
positive regulation of cell differentiationGO:00455972170.024
positive regulation of protein metabolic processGO:00512471780.023
response to inorganic substanceGO:00100353770.022
regulation of programmed cell deathGO:00430673410.022
positive regulation of molecular functionGO:00440932300.022
ribonucleotide metabolic processGO:00092592310.022
negative regulation of metabolic processGO:00098923310.022
secretionGO:00469033070.022
cation transportGO:00068123820.021
cellular lipid metabolic processGO:00442552080.021
central nervous system developmentGO:00074173110.021
positive regulation of phosphorylationGO:00423271770.021
protein localizationGO:00081041910.021
response to extracellular stimulusGO:00099913800.020
positive regulation of neuron differentiationGO:00456661260.020
organic cyclic compound catabolic processGO:19013611750.020
ribonucleoside triphosphate metabolic processGO:00091991410.020
regulation of intracellular signal transductionGO:19025312180.020
regulation of protein metabolic processGO:00512462890.020
regulation of protein localizationGO:0032880810.020
nucleoside phosphate metabolic processGO:00067532830.020
regulation of rna metabolic processGO:00512523910.020
purine ribonucleotide metabolic processGO:00091502270.020
positive regulation of cell projection organizationGO:00313461110.020
nitrogen compound transportGO:00717052290.020
regulation of cellular protein metabolic processGO:00322682670.019
response to nutrient levelsGO:00316673700.019
transmembrane transportGO:00550854120.019
cellular component assemblyGO:00226073600.019
regulation of cellular amino acid metabolic processGO:000652120.019
apoptotic processGO:00069153810.019
nucleotide catabolic processGO:00091661390.019
ion transmembrane transportGO:00342203650.019
regulation of system processGO:00440572080.019
carboxylic acid transportGO:00469421150.018
cellular ketone metabolic processGO:0042180510.018
regulation of cell differentiationGO:00455953200.018
organic substance catabolic processGO:19015753160.018
anatomical structure morphogenesisGO:00096532980.018
brain developmentGO:00074202470.018
response to oxidative stressGO:00069791860.018
regulation of apoptotic processGO:00429813350.018
cellular nitrogen compound catabolic processGO:00442701630.018
head developmentGO:00603222470.017
protein heterooligomerizationGO:0051291890.017
regulation of mapk cascadeGO:00434081160.017
positive regulation of nitrogen compound metabolic processGO:00511733340.017
nucleic acid templated transcriptionGO:00976593790.017
programmed cell deathGO:00125013920.017
single organism reproductive processGO:00447022970.017
organelle organizationGO:00069962660.017
ribonucleoside metabolic processGO:00091191740.017
positive regulation of protein modification processGO:00314011420.017
nucleobase containing compound catabolic processGO:00346551520.017
cell cycle checkpointGO:000007520.017
regulation of cellular ketone metabolic processGO:0010565270.017
cellular macromolecule localizationGO:00707271220.017
purine nucleotide metabolic processGO:00061632290.016
reproductionGO:00000032450.016
regenerationGO:00310991630.016
single organism organelle organizationGO:19025891800.016
response to hypoxiaGO:00016662310.016
cell cell signalingGO:00072673350.016
regulation of secretionGO:00510462240.016
purine nucleotide catabolic processGO:00061951360.016
negative regulation of programmed cell deathGO:00430691830.016
nucleoside metabolic processGO:00091161790.016
response to woundingGO:00096112540.016
nucleoside catabolic processGO:00091641260.016
intracellular transportGO:00469071850.015
female gonad developmentGO:0008585530.015
regulation of neurogenesisGO:00507672470.015
regulation of nucleic acid templated transcriptionGO:19035063800.015
regulation of protein phosphorylationGO:00019321830.015
heterocycle catabolic processGO:00467001670.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
rhythmic processGO:00485111560.015
negative regulation of biosynthetic processGO:00098901680.015
regulation of protein modification processGO:00313991940.015
organic acid transportGO:00158491160.015
negative regulation of macromolecule metabolic processGO:00106052600.014
positive regulation of protein phosphorylationGO:00019341350.014
aromatic compound catabolic processGO:00194391680.014
response to decreased oxygen levelsGO:00362932370.014
nucleotide metabolic processGO:00091172790.014
negative regulation of transportGO:00510511360.014
oligopeptide transportGO:000685740.014
regulation of transcription dna templatedGO:00063553740.014
sex differentiationGO:00075481130.014
negative regulation of cell deathGO:00605482290.014
mapk cascadeGO:00001651400.014
signal transduction by phosphorylationGO:00230141440.014
phospholipid metabolic processGO:0006644610.014
cation homeostasisGO:00550801950.014
blood circulationGO:00080151830.014
positive regulation of transportGO:00510502450.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
response to oxygen levelsGO:00704822650.014
neurological system processGO:00508772190.013
organophosphate biosynthetic processGO:00904071430.013
response to metal ionGO:00100382530.013
amide transportGO:00428861050.013
anion transportGO:00068201780.013
agingGO:00075682410.013
response to growth factorGO:00708481890.013
purine ribonucleoside metabolic processGO:00461281680.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
actin filament based processGO:0030029860.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
positive regulation of cellular biosynthetic processGO:00313282950.013
single organism biosynthetic processGO:00447113420.013
organonitrogen compound biosynthetic processGO:19015661670.013
multicellular organismal reproductive processGO:00486092330.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
positive regulation of mapk cascadeGO:0043410920.013
rna biosynthetic processGO:00327743800.013
purine nucleoside metabolic processGO:00422781690.013
regulation of secretion by cellGO:19035302080.013
multicellular organism reproductionGO:00325042330.013
regulation of purine nucleotide metabolic processGO:19005421150.013
actin cytoskeleton organizationGO:0030036730.013
circulatory system processGO:00030131830.013
positive regulation of catalytic activityGO:00430851840.013
ribonucleotide catabolic processGO:00092611360.013
defense responseGO:00069521940.013
positive regulation of signal transductionGO:00099671750.013
sulfur compound metabolic processGO:0006790700.013
establishment of protein localizationGO:00451841410.013
regulation of kinase activityGO:00435491170.012
single organism intracellular transportGO:19025821660.012
positive regulation of catabolic processGO:0009896780.012
protein transportGO:00150311320.012
transcription dna templatedGO:00063513770.012
regulation of nucleotide metabolic processGO:00061401170.012
negative regulation of apoptotic processGO:00430661810.012
macromolecular complex subunit organizationGO:00439333390.012
positive regulation of cell communicationGO:00106472710.012
positive regulation of gene expressionGO:00106282440.012
regulation of cellular catabolic processGO:00313291010.012
regulation of catabolic processGO:00098941130.012
response to other organismGO:00517072200.012
response to peptide hormoneGO:00434342780.012
response to molecule of bacterial originGO:00022371940.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
gonad developmentGO:00084061040.012
positive regulation of biosynthetic processGO:00098913190.012
regulation of nucleotide catabolic processGO:0030811650.012
response to bacteriumGO:00096172000.012
protein phosphorylationGO:00064683450.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
amino acid transportGO:0006865700.011
axis specificationGO:000979840.011
response to glucoseGO:00097491360.011
positive regulation of nucleotide metabolic processGO:0045981910.011
carbohydrate derivative catabolic processGO:19011361470.011
rho protein signal transductionGO:0007266110.011
secretion by cellGO:00329402480.011
purine ribonucleoside catabolic processGO:00461301240.011
response to carbohydrateGO:00097431830.011
chromosome segregationGO:000705920.011
proteolysisGO:00065081750.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
nucleoside phosphate catabolic processGO:19012921400.011
regulation of organelle organizationGO:0033043800.011
response to hexoseGO:00097461440.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
response to monosaccharideGO:00342841590.011
regulation of response to stressGO:00801341260.011
ovulation cycleGO:0042698670.011
multi organism reproductive processGO:00447032620.011
positive regulation of apoptotic processGO:00430651540.011
regulation of anatomical structure sizeGO:00900661350.011
purine ribonucleotide catabolic processGO:00091541360.011
cellular response to oxygen containing compoundGO:19017013860.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
response to acid chemicalGO:00011012220.011
cellular protein localizationGO:00346131220.011
regulation of membrane potentialGO:00423911100.011
ribonucleoside catabolic processGO:00424541260.011
development of primary sexual characteristicsGO:00451371070.011
dna integrity checkpointGO:003157020.011
defense response to gram negative bacteriumGO:005082930.011
regulation of transferase activityGO:00513381230.011
cation transmembrane transportGO:00986552630.011
reproductive processGO:00224143720.011
regulation of signal transductionGO:00099663180.011
cellular component movementGO:00069282480.010
cellular response to cytokine stimulusGO:00713451270.010
response to purine containing compoundGO:00140741260.010
positive regulation of cellular catabolic processGO:0031331710.010
response to external biotic stimulusGO:00432072210.010
female sex differentiationGO:0046660590.010
negative regulation of response to stimulusGO:00485851550.010
positive regulation of response to stimulusGO:00485842850.010
mitotic cell cycle checkpointGO:000709310.010
regulation of hydrolase activityGO:00513361430.010
negative regulation of nervous system developmentGO:0051961790.010
positive regulation of signalingGO:00230562700.010
cellular homeostasisGO:00197252520.010
single organism catabolic processGO:00447122830.010
synaptic transmissionGO:00072682350.010
reproductive system developmentGO:00614581280.010
metal ion transportGO:00300012890.010
inflammatory responseGO:00069541500.010

Appl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.034
sensory system diseaseDOID:005015500.020
eye diseaseDOID:561400.015
eye and adnexa diseaseDOID:149200.015
central nervous system diseaseDOID:33100.014