Rattus norvegicus

21 known processes

D2hgdh

D-2-hydroxyglutarate dehydrogenase

(Aliases: RGD1307976)

D2hgdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.080
single organism catabolic processGO:00447122830.080
carboxylic acid metabolic processGO:00197522890.072
catabolic processGO:00090563510.067
lipid metabolic processGO:00066292830.061
oxoacid metabolic processGO:00434362900.057
organophosphate metabolic processGO:00196373700.047
cellular catabolic processGO:00442482950.047
organic substance catabolic processGO:19015753160.045
carbohydrate derivative metabolic processGO:19011353460.044
cellular lipid metabolic processGO:00442552080.043
programmed cell deathGO:00125013920.040
nucleoside phosphate metabolic processGO:00067532830.040
central nervous system developmentGO:00074173110.039
cellular component biogenesisGO:00440853680.039
organelle organizationGO:00069962660.038
regulation of phosphorus metabolic processGO:00511743490.038
macromolecular complex subunit organizationGO:00439333390.037
organophosphate catabolic processGO:00464341480.035
ribonucleotide metabolic processGO:00092592310.035
ribose phosphate metabolic processGO:00196932350.034
regulation of signal transductionGO:00099663180.034
cellular ketone metabolic processGO:0042180510.033
fatty acid metabolic processGO:0006631990.033
cellular amino acid metabolic processGO:00065201070.033
phosphatidylinositol dephosphorylationGO:004685640.032
response to metal ionGO:00100382530.031
regulation of cellular amino acid metabolic processGO:000652120.031
rna biosynthetic processGO:00327743800.031
amine metabolic processGO:0009308380.030
nucleoside metabolic processGO:00091161790.030
single organism biosynthetic processGO:00447113420.029
cellular nitrogen compound catabolic processGO:00442701630.029
response to nutrient levelsGO:00316673700.029
response to purine containing compoundGO:00140741260.029
nucleotide metabolic processGO:00091172790.028
nucleobase containing small molecule metabolic processGO:00550863160.027
apoptotic processGO:00069153810.027
regulation of cellular ketone metabolic processGO:0010565270.027
protein complex subunit organizationGO:00718223020.027
response to extracellular stimulusGO:00099913800.027
purine nucleotide catabolic processGO:00061951360.027
regulation of nucleic acid templated transcriptionGO:19035063800.027
oxidation reduction processGO:00551143040.027
ribonucleoside triphosphate catabolic processGO:00092031220.027
aromatic compound catabolic processGO:00194391680.026
organonitrogen compound catabolic processGO:19015651790.026
protein complex biogenesisGO:00702712630.026
purine ribonucleotide catabolic processGO:00091541360.026
monocarboxylic acid metabolic processGO:00327871520.025
positive regulation of nitrogen compound metabolic processGO:00511733340.025
cell projection organizationGO:00300303020.025
single organism reproductive processGO:00447022970.025
organic cyclic compound catabolic processGO:19013611750.025
cellular amine metabolic processGO:0044106380.025
purine nucleotide metabolic processGO:00061632290.025
response to nutrientGO:00075842480.025
purine containing compound metabolic processGO:00725212530.024
purine nucleoside triphosphate catabolic processGO:00091461220.024
regulation of cellular amine metabolic processGO:003323880.024
regulation of apoptotic processGO:00429813350.024
head developmentGO:00603222470.024
reproductionGO:00000032450.024
single organism organelle organizationGO:19025891800.024
monovalent inorganic cation transportGO:00156721720.023
regulation of phosphate metabolic processGO:00192203490.023
organonitrogen compound biosynthetic processGO:19015661670.023
cellular component assemblyGO:00226073600.023
nucleotide catabolic processGO:00091661390.023
positive regulation of cell communicationGO:00106472710.023
response to inorganic substanceGO:00100353770.023
regulation of cellular component organizationGO:00511283680.023
nucleoside phosphate catabolic processGO:19012921400.022
multicellular organism reproductionGO:00325042330.022
lipid modificationGO:0030258520.022
ribonucleoside metabolic processGO:00091191740.022
positive regulation of cellular amine metabolic processGO:003324030.022
regulation of organelle organizationGO:0033043800.022
purine ribonucleoside triphosphate catabolic processGO:00092071220.022
reproductive processGO:00224143720.022
macromolecular complex assemblyGO:00650032730.022
ribonucleotide catabolic processGO:00092611360.021
small gtpase mediated signal transductionGO:0007264360.021
multicellular organism growthGO:003526410.021
chemical homeostasisGO:00488782920.021
cation transportGO:00068123820.021
purine nucleoside triphosphate metabolic processGO:00091441410.021
inorganic ion transmembrane transportGO:00986602290.021
regulation of intracellular signal transductionGO:19025312180.021
multicellular organismal reproductive processGO:00486092330.021
purine containing compound catabolic processGO:00725231380.020
nucleoside triphosphate metabolic processGO:00091411440.020
regulation of cell differentiationGO:00455953200.020
multi organism reproductive processGO:00447032620.020
purine ribonucleoside catabolic processGO:00461301240.020
purine nucleoside metabolic processGO:00422781690.020
regulation of membrane potentialGO:00423911100.020
ribonucleoside triphosphate metabolic processGO:00091991410.020
metal ion transportGO:00300012890.020
carbohydrate derivative catabolic processGO:19011361470.020
response to external biotic stimulusGO:00432072210.019
nucleoside triphosphate catabolic processGO:00091431230.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
neuronal action potentialGO:0019228350.019
purine ribonucleotide metabolic processGO:00091502270.019
protein phosphorylationGO:00064683450.019
nucleobase containing compound catabolic processGO:00346551520.019
response to decreased oxygen levelsGO:00362932370.019
glycosyl compound metabolic processGO:19016571820.019
rna metabolic processGO:00160704060.019
protein oligomerizationGO:00512591910.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
fatty acid catabolic processGO:0009062260.018
locomotionGO:00400112370.018
intracellular signal transductionGO:00355563140.018
protein complex assemblyGO:00064612630.018
negative regulation of metabolic processGO:00098923310.018
purine ribonucleoside metabolic processGO:00461281680.018
transcription dna templatedGO:00063513770.018
response to organophosphorusGO:00466831020.018
heterocycle catabolic processGO:00467001670.018
cellular component movementGO:00069282480.018
ras protein signal transductionGO:0007265290.018
regulation of neuron projection developmentGO:00109751610.017
nucleic acid templated transcriptionGO:00976593790.017
secretionGO:00469033070.017
regulation of programmed cell deathGO:00430673410.017
cellular response to oxygen containing compoundGO:19017013860.017
positive regulation of phosphate metabolic processGO:00459372620.017
brain developmentGO:00074202470.017
regulation of rna metabolic processGO:00512523910.017
positive regulation of response to stimulusGO:00485842850.017
cellular response to endogenous stimulusGO:00714953770.017
neurological system processGO:00508772190.017
action potentialGO:0001508540.017
neuron differentiationGO:00301823680.017
regulation of rna biosynthetic processGO:20011413810.017
nucleoside catabolic processGO:00091641260.017
organic acid catabolic processGO:0016054490.017
regulation of cell projection organizationGO:00313441750.016
agingGO:00075682410.016
negative regulation of apoptotic processGO:00430661810.016
ribonucleoside catabolic processGO:00424541260.016
vesicle mediated transportGO:00161921810.016
positive regulation of phosphorus metabolic processGO:00105622620.016
small molecule catabolic processGO:0044282590.016
regulation of ion transportGO:00432692450.015
purine nucleoside catabolic processGO:00061521240.015
regulation of cellular localizationGO:00603412630.015
positive regulation of rna metabolic processGO:00512542030.015
response to bacteriumGO:00096172000.015
membrane organizationGO:0061024940.015
response to oxygen levelsGO:00704822650.015
regenerationGO:00310991630.015
positive regulation of signal transductionGO:00099671750.015
negative regulation of programmed cell deathGO:00430691830.015
response to hypoxiaGO:00016662310.015
regulation of transcription dna templatedGO:00063553740.015
regulation of cell proliferationGO:00421273590.015
protein homooligomerizationGO:0051260910.015
ion transmembrane transportGO:00342203650.015
tissue developmentGO:00098882520.015
intracellular transportGO:00469071850.014
regulation of neurogenesisGO:00507672470.014
response to starvationGO:0042594590.014
glycosyl compound catabolic processGO:19016581260.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
nitrogen compound transportGO:00717052290.014
gland developmentGO:00487321550.014
regulation of system processGO:00440572080.014
neuron developmentGO:00486662860.014
adult locomotory behaviorGO:000834440.014
regulation of purine nucleotide metabolic processGO:19005421150.014
sexual reproductionGO:00199531480.014
cofactor metabolic processGO:0051186950.014
peptidyl amino acid modificationGO:00181931260.014
cellular homeostasisGO:00197252520.014
lipid catabolic processGO:0016042460.013
response to corticosteroidGO:00319602350.013
ensheathment of neuronsGO:0007272400.013
hormone transportGO:00099141210.013
peptide secretionGO:0002790860.013
regulation of hormone levelsGO:00108171870.013
negative regulation of macromolecule metabolic processGO:00106052600.013
growthGO:00400071650.013
telencephalon developmentGO:0021537620.013
cellular response to stressGO:00335542690.013
homeostatic processGO:00425923310.013
response to carbohydrateGO:00097431830.013
single organism membrane organizationGO:0044802740.013
negative regulation of cellular metabolic processGO:00313242810.013
inorganic cation transmembrane transportGO:00986622020.013
cell morphogenesisGO:00009021420.013
response to biotic stimulusGO:00096072260.013
regulation of phosphorylationGO:00423252480.013
amide transportGO:00428861050.013
guanosine containing compound metabolic processGO:1901068740.013
response to acid chemicalGO:00011012220.013
blood circulationGO:00080151830.012
cellular response to extracellular stimulusGO:0031668730.012
dephosphorylationGO:0016311980.012
multi multicellular organism processGO:00447061380.012
transmission of nerve impulseGO:0019226420.012
cation transmembrane transportGO:00986552630.012
cell adhesionGO:00071551100.012
gtp metabolic processGO:0046039720.012
regulation of peptide transportGO:0090087870.012
macromolecule localizationGO:00330362520.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
negative regulation of cell deathGO:00605482290.012
gamete generationGO:00072761240.012
positive regulation of cellular component organizationGO:00511302000.012
regulation of secretionGO:00510462240.012
carbohydrate derivative biosynthetic processGO:19011371240.012
cellular response to lipidGO:00713962010.012
regulation of catabolic processGO:00098941130.012
ion homeostasisGO:00508012120.012
transcription from rna polymerase ii promoterGO:00063662520.012
regulation of multicellular organismal developmentGO:20000263760.012
transmembrane transportGO:00550854120.011
axon ensheathmentGO:0008366400.011
cell part morphogenesisGO:00329901230.011
regulation of neuron differentiationGO:00456642080.011
cellular response to nutrient levelsGO:0031669600.011
rho protein signal transductionGO:0007266110.011
peptide hormone secretionGO:0030072840.011
cellular response to metal ionGO:0071248550.011
cellular response to external stimulusGO:00714961180.011
regulation of peptide hormone secretionGO:0090276800.011
hormone secretionGO:00468791150.011
response to vitaminGO:00332731310.011
peptide transportGO:0015833970.011
cell cell signalingGO:00072673350.011
regulation of hormone secretionGO:00468831060.011
negative regulation of transportGO:00510511360.011
developmental process involved in reproductionGO:00030061590.011
embryonic pattern specificationGO:000988010.011
metal ion homeostasisGO:00550651860.011
response to peptideGO:19016522920.011
regulation of catalytic activityGO:00507903040.011
cellular lipid catabolic processGO:0044242370.011
response to peptide hormoneGO:00434342780.011
cellular macromolecule localizationGO:00707271220.011
localization of cellGO:00516742020.011
regulation of phosphatidylinositol dephosphorylationGO:006030410.011
cellular response to hormone stimulusGO:00328702470.011
protein targetingGO:0006605610.011
negative regulation of cellular component organizationGO:0051129830.010
regulation of nucleotide metabolic processGO:00061401170.010
anion transportGO:00068201780.010
cellular protein localizationGO:00346131220.010
response to ethanolGO:00454711620.010
signal releaseGO:00230611450.010
positive regulation of protein metabolic processGO:00512471780.010
protein localizationGO:00081041910.010
establishment of protein localizationGO:00451841410.010
cytoplasmic transportGO:00164821150.010
single organism intracellular transportGO:19025821660.010
g protein coupled receptor signaling pathwayGO:00071862420.010
regulation of cell growthGO:0001558850.010
female pregnancyGO:00075651220.010
positive regulation of macromolecule biosynthetic processGO:00105572470.010
olfactory behaviorGO:004204820.010
regulation of nucleotide catabolic processGO:0030811650.010
lipid storageGO:001991510.010
cellular component maintenanceGO:004395440.010
synaptic transmissionGO:00072682350.010
nucleotide biosynthetic processGO:0009165980.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
actin filament based processGO:0030029860.010

D2hgdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.023
nervous system diseaseDOID:86300.022
disease of anatomical entityDOID:700.022
inherited metabolic disorderDOID:65500.016
central nervous system diseaseDOID:33100.015
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
organ system cancerDOID:005068600.010