IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Klrh1

killer cell lectin-like receptor subfamily H, member 1

RGD: 621452
Entrez: 246043
UniProtKB: Q8K4F1

Process Predictions
Disease Predictions

Klrh1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
response to biotic stimulus	GO:0009607	226	0.459
response to external biotic stimulus	GO:0043207	221	0.265
response to lipopolysaccharide	GO:0032496	191	0.183
regulation of hormone levels	GO:0010817	187	0.165
reproductive process	GO:0022414	372	0.155
cation transport	GO:0006812	382	0.144
cation transmembrane transport	GO:0098655	263	0.124
response to molecule of bacterial origin	GO:0002237	194	0.120
response to cytokine	GO:0034097	215	0.112
hormone metabolic process	GO:0042445	69	0.100
response to peptide	GO:1901652	292	0.100
growth	GO:0040007	165	0.096
blood circulation	GO:0008015	183	0.093
cellular chemical homeostasis	GO:0055082	247	0.081
response to other organism	GO:0051707	220	0.080
nitrogen compound transport	GO:0071705	229	0.080
monovalent inorganic cation transport	GO:0015672	172	0.078
positive regulation of multicellular organismal process	GO:0051240	387	0.077
lipid metabolic process	GO:0006629	283	0.073
response to peptide hormone	GO:0043434	278	0.073
homeostatic process	GO:0042592	331	0.072
cellular ion homeostasis	GO:0006873	184	0.064
response to radiation	GO:0009314	137	0.064
chemical homeostasis	GO:0048878	292	0.063
neurological system process	GO:0050877	219	0.062
intracellular signal transduction	GO:0035556	314	0.060
cation homeostasis	GO:0055080	195	0.060
regulation of protein phosphorylation	GO:0001932	183	0.059
regulation of secretion	GO:0051046	224	0.058
multi organism reproductive process	GO:0044703	262	0.057
apoptotic process	GO:0006915	381	0.057
reproduction	GO:0000003	245	0.057
circulatory system process	GO:0003013	183	0.056
sensory perception	GO:0007600	101	0.055
ion transmembrane transport	GO:0034220	365	0.055
response to growth factor	GO:0070848	189	0.054
regulation of nervous system development	GO:0051960	264	0.051
response to estrogen	GO:0043627	232	0.051
negative regulation of cell death	GO:0060548	229	0.050
single organism reproductive process	GO:0044702	297	0.046
positive regulation of biosynthetic process	GO:0009891	319	0.044
response to nutrient	GO:0007584	248	0.044
response to reactive oxygen species	GO:0000302	120	0.044
positive regulation of cell communication	GO:0010647	271	0.043
regulation of ion transport	GO:0043269	245	0.043
inorganic cation transmembrane transport	GO:0098662	202	0.042
regulation of cellular protein metabolic process	GO:0032268	267	0.041
cellular homeostasis	GO:0019725	252	0.041
response to ethanol	GO:0045471	162	0.041
negative regulation of metabolic process	GO:0009892	331	0.041
response to carbohydrate	GO:0009743	183	0.041
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.040
metal ion transport	GO:0030001	289	0.040
positive regulation of protein phosphorylation	GO:0001934	135	0.039
sexual reproduction	GO:0019953	148	0.039
single organism biosynthetic process	GO:0044711	342	0.038
positive regulation of nervous system development	GO:0051962	178	0.038
positive regulation of phosphorus metabolic process	GO:0010562	262	0.038
regulation of protein metabolic process	GO:0051246	289	0.038
positive regulation of cellular protein metabolic process	GO:0032270	167	0.037
circadian rhythm	GO:0007623	88	0.036
regulation of neurogenesis	GO:0050767	247	0.036
multicellular organism reproduction	GO:0032504	233	0.036
regulation of transferase activity	GO:0051338	123	0.035
multicellular organismal reproductive process	GO:0048609	233	0.035
regulation of cell development	GO:0060284	263	0.035
cellular cation homeostasis	GO:0030003	180	0.035
regulation of system process	GO:0044057	208	0.033
inorganic ion transmembrane transport	GO:0098660	229	0.032
regulation of molecular function	GO:0065009	398	0.032
cellular response to oxygen containing compound	GO:1901701	386	0.032
regulation of programmed cell death	GO:0043067	341	0.032
activation of janus kinase activity	GO:0042976	5	0.032
protein phosphorylation	GO:0006468	345	0.032
response to bacterium	GO:0009617	200	0.031
programmed cell death	GO:0012501	392	0.031
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.031
regulation of secretion by cell	GO:1903530	208	0.031
response to extracellular stimulus	GO:0009991	380	0.030
positive regulation of secretion by cell	GO:1903532	128	0.030
protein complex subunit organization	GO:0071822	302	0.030
anatomical structure morphogenesis	GO:0009653	298	0.029
ion homeostasis	GO:0050801	212	0.029
metal ion homeostasis	GO:0055065	186	0.029
regulation of protein modification process	GO:0031399	194	0.029
regulation of apoptotic process	GO:0042981	335	0.029
cell growth	GO:0016049	104	0.029
multi multicellular organism process	GO:0044706	138	0.028
innate immune response	GO:0045087	35	0.028
transmembrane transport	GO:0055085	412	0.028
cellular response to stress	GO:0033554	269	0.027
response to inorganic substance	GO:0010035	377	0.027
calcitriol biosynthetic process from calciol	GO:0036378	2	0.027
regulation of multicellular organismal development	GO:2000026	376	0.026
cellular response to abiotic stimulus	GO:0071214	85	0.026
hormone transport	GO:0009914	121	0.025
regulation of growth	GO:0040008	105	0.025
regulation of catalytic activity	GO:0050790	304	0.025
regulation of phosphorylation	GO:0042325	248	0.025
cellular component biogenesis	GO:0044085	368	0.024
protein complex assembly	GO:0006461	263	0.024
positive regulation of protein modification process	GO:0031401	142	0.024
regulation of blood pressure	GO:0008217	83	0.024
regulation of cell differentiation	GO:0045595	320	0.023
divalent inorganic cation homeostasis	GO:0072507	165	0.023
response to oxidative stress	GO:0006979	186	0.022
divalent metal ion transport	GO:0070838	132	0.022
regulation of peptide transport	GO:0090087	87	0.022
potassium ion transmembrane transport	GO:0071805	71	0.022
macromolecule localization	GO:0033036	252	0.022
negative regulation of programmed cell death	GO:0043069	183	0.022
reactive oxygen species metabolic process	GO:0072593	37	0.021
aging	GO:0007568	241	0.021
peptidyl tyrosine modification	GO:0018212	72	0.021
positive regulation of protein metabolic process	GO:0051247	178	0.021
respiratory system development	GO:0060541	45	0.021
response to ionizing radiation	GO:0010212	59	0.020
jak stat cascade	GO:0007259	26	0.020
signal release	GO:0023061	145	0.020
regulation of phosphate metabolic process	GO:0019220	349	0.020
positive regulation of cell proliferation	GO:0008284	249	0.019
regulation of kinase activity	GO:0043549	117	0.019
positive regulation of cellular biosynthetic process	GO:0031328	295	0.019
rna metabolic process	GO:0016070	406	0.019
response to ketone	GO:1901654	182	0.019
cellular catabolic process	GO:0044248	295	0.019
cellular amine metabolic process	GO:0044106	38	0.019
response to mechanical stimulus	GO:0009612	134	0.018
cellular component assembly	GO:0022607	360	0.018
response to estradiol	GO:0032355	164	0.018
positive regulation of molecular function	GO:0044093	230	0.018
heart morphogenesis	GO:0003007	3	0.018
response to nutrient levels	GO:0031667	370	0.018
amine metabolic process	GO:0009308	38	0.018
response to transforming growth factor beta	GO:0071559	46	0.018
cellular response to cytokine stimulus	GO:0071345	127	0.017
developmental process involved in reproduction	GO:0003006	159	0.017
response to decreased oxygen levels	GO:0036293	237	0.017
positive regulation of cell development	GO:0010720	176	0.017
activation of protein kinase activity	GO:0032147	47	0.016
regulation of protein kinase activity	GO:0045859	105	0.016
lipid biosynthetic process	GO:0008610	128	0.016
macromolecular complex assembly	GO:0065003	273	0.016
negative regulation of apoptotic process	GO:0043066	181	0.016
regulation of neuron death	GO:1901214	115	0.016
regulation of cell proliferation	GO:0042127	359	0.016
cellular response to endogenous stimulus	GO:0071495	377	0.016
immune response	GO:0006955	104	0.016
carbohydrate derivative metabolic process	GO:1901135	346	0.016
regulation of cellular ketone metabolic process	GO:0010565	27	0.015
cellular response to oxidative stress	GO:0034599	76	0.015
cellular metal ion homeostasis	GO:0006875	172	0.015
behavior	GO:0007610	205	0.015
cellular amino acid metabolic process	GO:0006520	107	0.015
positive regulation of phosphate metabolic process	GO:0045937	262	0.015
regulation of membrane potential	GO:0042391	110	0.015
positive regulation of neuron differentiation	GO:0045666	126	0.015
cellular response to reactive oxygen species	GO:0034614	55	0.015
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.015
positive regulation of intracellular signal transduction	GO:1902533	138	0.015
steroid metabolic process	GO:0008202	73	0.015
regulation of neuron differentiation	GO:0045664	208	0.015
regulation of intracellular signal transduction	GO:1902531	218	0.014
positive regulation of transport	GO:0051050	245	0.014
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
rhythmic process	GO:0048511	156	0.014
cellular response to hormone stimulus	GO:0032870	247	0.014
protein maturation	GO:0051604	68	0.014
male gonad development	GO:0008584	59	0.014
potassium ion transport	GO:0006813	97	0.014
response to hydrogen peroxide	GO:0042542	89	0.014
male sex differentiation	GO:0046661	64	0.014
cellular calcium ion homeostasis	GO:0006874	160	0.014
reactive nitrogen species metabolic process	GO:2001057	1	0.014
divalent inorganic cation transport	GO:0072511	134	0.014
cellular response to external stimulus	GO:0071496	118	0.014
regulation of ossification	GO:0030278	32	0.014
response to metal ion	GO:0010038	253	0.013
isoprenoid metabolic process	GO:0006720	45	0.013
neuron differentiation	GO:0030182	368	0.013
circulatory system development	GO:0072359	134	0.013
regulation of cellular localization	GO:0060341	263	0.013
regulation of lipid biosynthetic process	GO:0046890	38	0.013
hormone biosynthetic process	GO:0042446	25	0.013
muscle cell proliferation	GO:0033002	84	0.013
gamete generation	GO:0007276	124	0.013
positive regulation of response to stimulus	GO:0048584	285	0.013
response to alkaloid	GO:0043279	132	0.013
positive regulation of transferase activity	GO:0051347	81	0.013
rna biosynthetic process	GO:0032774	380	0.013
peptidyl tyrosine phosphorylation	GO:0018108	72	0.013
sensory organ development	GO:0007423	74	0.013
negative regulation of multicellular organismal process	GO:0051241	203	0.013
protein complex biogenesis	GO:0070271	263	0.013
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.013
oxoacid metabolic process	GO:0043436	290	0.012
positive regulation of jak stat cascade	GO:0046427	19	0.012
regulation of anatomical structure morphogenesis	GO:0022603	141	0.012
response to oxygen levels	GO:0070482	265	0.012
female pregnancy	GO:0007565	122	0.012
organic anion transport	GO:0015711	132	0.012
cellular response to transforming growth factor beta stimulus	GO:0071560	41	0.012
response to monosaccharide	GO:0034284	159	0.012
anion transport	GO:0006820	178	0.012
transcription dna templated	GO:0006351	377	0.012
positive regulation of neurogenesis	GO:0050769	165	0.012
response to transition metal nanoparticle	GO:1990267	122	0.012
inflammatory response	GO:0006954	150	0.011
protein oligomerization	GO:0051259	191	0.011
negative regulation of natural killer cell mediated cytotoxicity	GO:0045953	4	0.011
regulation of cell motility	GO:2000145	131	0.011
positive regulation of growth	GO:0045927	55	0.011
heart development	GO:0007507	72	0.011
glucose homeostasis	GO:0042593	75	0.011
response to glucose	GO:0009749	136	0.011
negative regulation of innate immune response	GO:0045824	4	0.011
calcium ion transport	GO:0006816	131	0.011
organic acid metabolic process	GO:0006082	292	0.011
vitamin d3 metabolic process	GO:0070640	2	0.011
cellular nitrogen compound catabolic process	GO:0044270	163	0.011
cardiovascular system development	GO:0072358	134	0.011
defense response	GO:0006952	194	0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.011
catabolic process	GO:0009056	351	0.011
regulation of rna biosynthetic process	GO:2001141	381	0.011
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.011
positive regulation of protein kinase activity	GO:0045860	73	0.011
response to hypoxia	GO:0001666	231	0.011
response to hexose	GO:0009746	144	0.011
transcription from rna polymerase ii promoter	GO:0006366	252	0.011
regulation of homeostatic process	GO:0032844	101	0.011
regulation of rna metabolic process	GO:0051252	391	0.011
negative regulation of macromolecule metabolic process	GO:0010605	260	0.011
regulation of cellular amine metabolic process	GO:0033238	8	0.011
positive regulation of gene expression	GO:0010628	244	0.011
positive regulation of signal transduction	GO:0009967	175	0.010
response to light stimulus	GO:0009416	52	0.010
sensory perception of bitter taste	GO:0050913	4	0.010
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.010
peptidyl amino acid modification	GO:0018193	126	0.010
macromolecular complex subunit organization	GO:0043933	339	0.010
negative regulation of molecular function	GO:0044092	133	0.010
defense response to gram negative bacterium	GO:0050829	3	0.010
positive regulation of phosphorylation	GO:0042327	177	0.010
negative regulation of catalytic activity	GO:0043086	103	0.010
cellular hormone metabolic process	GO:0034754	49	0.010
positive regulation of programmed cell death	GO:0043068	157	0.010
lung development	GO:0030324	43	0.010
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.010
neuron projection development	GO:0031175	273	0.010
proteolysis	GO:0006508	175	0.010
cellular response to monosaccharide stimulus	GO:0071326	67	0.010
regulation of jak stat cascade	GO:0046425	21	0.010

Klrh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.023
sensory system disease	DOID:0050155	0.022
nervous system disease	DOID:863	0.022
disease of anatomical entity	DOID:7	0.022
eye and adnexa disease	DOID:1492	0.018
eye disease	DOID:5614	0.018
central nervous system disease	DOID:331	0.011

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