Rattus norvegicus

116 known processes

P2ry12

purinergic receptor P2Y, G-protein coupled, 12

(Aliases: P2y12)

P2ry12 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to bacteriumGO:00096172000.239
agingGO:00075682410.133
defense responseGO:00069521940.128
regulation of cell proliferationGO:00421273590.092
vasculature developmentGO:0001944700.087
blood circulationGO:00080151830.086
g protein coupled receptor signaling pathwayGO:00071862420.074
positive regulation of nitrogen compound metabolic processGO:00511733340.074
positive regulation of response to stimulusGO:00485842850.066
response to inorganic substanceGO:00100353770.064
circulatory system processGO:00030131830.062
t cell chemotaxisGO:001081820.060
oxoacid metabolic processGO:00434362900.059
cellular response to endogenous stimulusGO:00714953770.057
central nervous system developmentGO:00074173110.057
response to nutrientGO:00075842480.057
negative regulation of developmental processGO:00510931250.055
response to estrogenGO:00436272320.055
chemical homeostasisGO:00488782920.055
head developmentGO:00603222470.054
cellular response to lipidGO:00713962010.054
neuron developmentGO:00486662860.054
catabolic processGO:00090563510.051
angiogenesisGO:0001525530.050
regulation of neutrophil migrationGO:190262260.049
regulation of protein phosphorylationGO:00019321830.048
cellular amino acid metabolic processGO:00065201070.047
regulation of angiogenesisGO:0045765390.047
cellular catabolic processGO:00442482950.047
inflammatory responseGO:00069541500.047
macromolecular complex assemblyGO:00650032730.046
response to extracellular stimulusGO:00099913800.045
anatomical structure morphogenesisGO:00096532980.044
inorganic cation transmembrane transportGO:00986622020.044
positive regulation of multicellular organismal processGO:00512403870.043
reproductionGO:00000032450.043
regulation of molecular functionGO:00650093980.043
cellular response to growth factor stimulusGO:00713631620.042
regulation of phosphate metabolic processGO:00192203490.042
blood vessel developmentGO:0001568690.041
response to woundingGO:00096112540.041
small gtpase mediated signal transductionGO:0007264360.041
regulation of cell developmentGO:00602842630.041
immune system processGO:00023762040.040
regulation of signal transductionGO:00099663180.040
cellular response to oxygen containing compoundGO:19017013860.039
locomotionGO:00400112370.039
blood vessel morphogenesisGO:0048514580.039
response to toxic substanceGO:00096361330.038
response to growth factorGO:00708481890.038
regulation of sodium ion transmembrane transporter activityGO:200064940.037
cation homeostasisGO:00550801950.037
regulation of nucleic acid templated transcriptionGO:19035063800.037
negative regulation of response to stimulusGO:00485851550.036
ras protein signal transductionGO:0007265290.036
neuron differentiationGO:00301823680.035
cell activationGO:0001775970.035
response to other organismGO:00517072200.035
regulation of intracellular signal transductionGO:19025312180.035
regulation of phosphorus metabolic processGO:00511743490.034
reproductive processGO:00224143720.034
gastrulationGO:000736920.033
regulation of chronic inflammatory response to non antigenic stimulusGO:000288010.032
circulatory system developmentGO:00723591340.032
response to cytokineGO:00340972150.031
cellular response to nitrogen compoundGO:19016992100.031
positive regulation of phosphorus metabolic processGO:00105622620.031
protein complex biogenesisGO:00702712630.031
regulation of phosphorylationGO:00423252480.031
cellular response to organonitrogen compoundGO:00714171970.031
positive regulation of phosphate metabolic processGO:00459372620.030
intracellular signal transductionGO:00355563140.030
cellular amine metabolic processGO:0044106380.030
regulation of apoptotic processGO:00429813350.030
regulation of response to stressGO:00801341260.030
developmental growthGO:00485891000.030
negative regulation of cell proliferationGO:00082851190.029
response to external biotic stimulusGO:00432072210.029
cellular response to histamineGO:007142030.029
vascular process in circulatory systemGO:0003018960.029
positive regulation of cell communicationGO:00106472710.029
amine metabolic processGO:0009308380.029
response to nutrient levelsGO:00316673700.029
cellular response to cytokine stimulusGO:00713451270.028
cardiovascular system developmentGO:00723581340.028
regulation of cellular protein metabolic processGO:00322682670.028
t cell tolerance inductionGO:000251730.027
positive regulation of cellular protein metabolic processGO:00322701670.027
response to oxygen levelsGO:00704822650.027
apoptotic processGO:00069153810.027
regulation of anatomical structure morphogenesisGO:00226031410.027
response to histamineGO:003477630.027
ion homeostasisGO:00508012120.027
positive regulation of protein modification processGO:00314011420.026
negative regulation of multicellular organismal processGO:00512412030.026
protein oligomerizationGO:00512591910.026
angioblast cell migrationGO:003547610.026
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.025
Human Mouse
positive regulation of cell proliferationGO:00082842490.025
muscle system processGO:00030121150.025
regulation of ion transmembrane transporter activityGO:0032412480.025
regulation of blood vessel sizeGO:0050880890.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
response to metal ionGO:00100382530.024
positive regulation of transcription dna templatedGO:00458931970.024
response to biotic stimulusGO:00096072260.024
positive regulation of protein phosphorylationGO:00019341350.024
lymphocyte chemotaxisGO:004824730.024
regulation of anatomical structure sizeGO:00900661350.024
multicellular organismal reproductive processGO:00486092330.024
cellular component biogenesisGO:00440853680.023
immune responseGO:00069551040.023
regulation of cellular amine metabolic processGO:003323880.023
transmembrane transportGO:00550854120.023
positive regulation of phosphorylationGO:00423271770.023
positive regulation of signalingGO:00230562700.023
intracellular transportGO:00469071850.022
regulation of cellular amino acid metabolic processGO:000652120.022
muscle tissue developmentGO:0060537580.022
negative regulation of programmed cell deathGO:00430691830.022
negative regulation of natural killer cell mediated immunityGO:000271640.022
regulation of protein modification processGO:00313991940.021
response to lipopolysaccharideGO:00324961910.021
cellular calcium ion homeostasisGO:00068741600.021
calcium ion transportGO:00068161310.021
regulation of cell differentiationGO:00455953200.021
wound healingGO:00420601220.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
macromolecule localizationGO:00330362520.021
brain developmentGO:00074202470.021
regulation of tube sizeGO:0035150890.020
striated muscle tissue developmentGO:0014706580.020
negative regulation of neutrophil apoptotic processGO:003303030.020
cellular macromolecule localizationGO:00707271220.020
cellular homeostasisGO:00197252520.020
telencephalon developmentGO:0021537620.020
regulation of chronic inflammatory responseGO:000267630.020
neuromuscular processGO:005090520.020
cardiac muscle contractionGO:0060048270.020
heart contractionGO:0060047570.020
glycosyl compound metabolic processGO:19016571820.020
regulation of system processGO:00440572080.019
proteolysisGO:00065081750.019
regulation of neurogenesisGO:00507672470.019
negative regulation of protein metabolic processGO:00512481140.019
regulation of protein metabolic processGO:00512462890.019
homeostatic processGO:00425923310.019
positive regulation of programmed cell deathGO:00430681570.019
regulation of cellular ketone metabolic processGO:0010565270.019
adenosine receptor signaling pathwayGO:000197370.019
regulation of vasculature developmentGO:1901342440.019
tube morphogenesisGO:0035239230.019
protein complex assemblyGO:00064612630.019
cell morphogenesis involved in differentiationGO:00009041190.018
forebrain developmentGO:0030900980.018
neuron projection developmentGO:00311752730.018
positive regulation of cellular amine metabolic processGO:003324030.018
regulation of programmed cell deathGO:00430673410.018
regulation of neuron projection developmentGO:00109751610.018
biological adhesionGO:00226101100.018
cell morphogenesis involved in neuron differentiationGO:00486671060.017
cytosolic calcium ion homeostasisGO:00514801400.017
negative regulation of apoptotic processGO:00430661810.017
negative regulation of gene expressionGO:00106291990.017
positive regulation of long term synaptic potentiationGO:190027340.017
cellular chemical homeostasisGO:00550822470.017
axon developmentGO:0061564960.017
organophosphate catabolic processGO:00464341480.017
cellular cation homeostasisGO:00300031800.017
organonitrogen compound catabolic processGO:19015651790.017
transcription from rna polymerase ii promoterGO:00063662520.017
gliogenesisGO:0042063930.017
regulation of blood circulationGO:19035221100.017
regulation of rna biosynthetic processGO:20011413810.017
multicellular organism growthGO:003526410.017
multi organism reproductive processGO:00447032620.017
cellular response to alcoholGO:0097306870.017
positive regulation of mapk cascadeGO:0043410920.017
motor neuron axon guidanceGO:000804510.017
lymphocyte migrationGO:007267630.017
purine ribonucleoside metabolic processGO:00461281680.017
organic acid metabolic processGO:00060822920.017
macrophage chemotaxisGO:004824620.016
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.016
response to alkaloidGO:00432791320.016
positive regulation of biosynthetic processGO:00098913190.016
organ morphogenesisGO:0009887750.016
carbohydrate derivative metabolic processGO:19011353460.016
multicellular organism reproductionGO:00325042330.016
negative regulation of cell differentiationGO:0045596990.016
purine nucleoside catabolic processGO:00061521240.016
metanephric tubule morphogenesisGO:007217320.016
organic cyclic compound catabolic processGO:19013611750.016
neutrophil apoptotic processGO:000178140.016
choline transportGO:001587140.016
sequestering of metal ionGO:005123890.015
positive regulation of rna metabolic processGO:00512542030.015
g protein coupled purinergic receptor signaling pathwayGO:003558880.015
negative regulation of chronic inflammatory responseGO:000267720.015
acute inflammatory responseGO:0002526580.015
positive regulation of blood circulationGO:1903524650.015
programmed cell deathGO:00125013920.015
regulation of neuron differentiationGO:00456642080.015
regenerationGO:00310991630.015
response to oxidative stressGO:00069791860.015
response to purine containing compoundGO:00140741260.014
single organism biosynthetic processGO:00447113420.014
regulation of response to external stimulusGO:00321011060.014
regulation of transporter activityGO:0032409500.014
sequestering of calcium ionGO:005120880.014
vasodilationGO:0042311440.014
regulation of catabolic processGO:00098941130.014
protein transportGO:00150311320.014
regulation of synaptic plasticityGO:0048167700.014
regulation of cellular component movementGO:00512701500.014
response to carbohydrateGO:00097431830.014
growthGO:00400071650.014
negative regulation of innate immune responseGO:004582440.014
response to glucocorticoidGO:00513842230.014
protein phosphorylationGO:00064683450.014
positive regulation of protein metabolic processGO:00512471780.014
positive regulation of intracellular signal transductionGO:19025331380.014
positive regulation of molecular functionGO:00440932300.014
female sex differentiationGO:0046660590.014
potassium ion transportGO:0006813970.014
regulation of cellular localizationGO:00603412630.014
single organismal cell cell adhesionGO:0016337420.013
regulation of transmembrane transporter activityGO:0022898490.013
cellular protein localizationGO:00346131220.013
negative regulation of cell communicationGO:00106481580.013
positive regulation of developmental processGO:00510942830.013
rna biosynthetic processGO:00327743800.013
positive regulation of cellular biosynthetic processGO:00313282950.013
cellular component movementGO:00069282480.013
organ formationGO:004864530.013
negative regulation of signalingGO:00230571570.013
platelet aggregationGO:007052740.013
axonogenesisGO:0007409710.013
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.013
leukocyte activationGO:0045321760.013
cell part morphogenesisGO:00329901230.013
single organism reproductive processGO:00447022970.013
response to mechanical stimulusGO:00096121340.013
rho protein signal transductionGO:0007266110.013
adult locomotory behaviorGO:000834440.013
carboxylic acid metabolic processGO:00197522890.013
cell type specific apoptotic processGO:00972851340.013
negative regulation of biosynthetic processGO:00098901680.013
nucleoside triphosphate catabolic processGO:00091431230.013
protein localizationGO:00081041910.013
positive regulation of cell deathGO:00109421840.012
negative regulation of protein modification processGO:0031400520.012
ion transmembrane transportGO:00342203650.012
negative regulation of macromolecule metabolic processGO:00106052600.012
divalent metal ion transportGO:00708381320.012
cellular response to extracellular stimulusGO:0031668730.012
startle responseGO:000196420.012
negative regulation of molecular functionGO:00440921330.012
cell projection organizationGO:00300303020.012
organic hydroxy compound transportGO:0015850770.012
regulation of ion transportGO:00432692450.012
regulation of response to woundingGO:1903034690.012
cellular response to biotic stimulusGO:0071216590.012
regulation of hydrolase activityGO:00513361430.012
tissue developmentGO:00098882520.012
positive regulation of neuron differentiationGO:00456661260.012
negative regulation of metabolic processGO:00098923310.012
axis specificationGO:000979840.012
regulation of kinase activityGO:00435491170.012
inflammatory response to antigenic stimulusGO:0002437180.012
cation transmembrane transportGO:00986552630.011
response to monosaccharideGO:00342841590.011
negative regulation of cellular metabolic processGO:00313242810.011
response to acid chemicalGO:00011012220.011
kidney developmentGO:0001822670.011
positive regulation of interleukin 1 beta secretionGO:005071830.011
cellular response to lipopolysaccharideGO:0071222550.011
response to radiationGO:00093141370.011
purine nucleoside metabolic processGO:00422781690.011
regulation of respiratory gaseous exchangeGO:004357620.011
single organism catabolic processGO:00447122830.011
transcription dna templatedGO:00063513770.011
protein homooligomerizationGO:0051260910.011
regulation of multicellular organismal developmentGO:20000263760.011
t cell migrationGO:007267820.011
regulation of defense responseGO:0031347680.011
sensory perceptionGO:00076001010.011
regulation of catalytic activityGO:00507903040.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
purine containing compound metabolic processGO:00725212530.011
cellular nitrogen compound catabolic processGO:00442701630.011
cell migrationGO:00164771970.011
cellular ketone metabolic processGO:0042180510.011
astrocyte activationGO:004814340.011
cellular component assemblyGO:00226073600.011
regulation of secretionGO:00510462240.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
purine nucleotide catabolic processGO:00061951360.011
negative regulation of cellular protein metabolic processGO:00322691060.011
response to testosteroneGO:0033574550.011
glucose homeostasisGO:0042593750.011
positive regulation of rna biosynthetic processGO:19026801970.011
regulation of transcription dna templatedGO:00063553740.010
nucleotide catabolic processGO:00091661390.010
regulation of cell motilityGO:20001451310.010
regulation of alpha beta t cell activationGO:004663420.010
muscle contractionGO:0006936880.010
organic substance catabolic processGO:19015753160.010
odontogenesisGO:0042476320.010
sensory perception of bitter tasteGO:005091340.010
negative regulation of vascular permeabilityGO:004311630.010
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.010
catecholamine secretionGO:0050432330.010
response to corticosteroidGO:00319602350.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
heterocycle catabolic processGO:00467001670.010
regulation of rna metabolic processGO:00512523910.010
reactive oxygen species metabolic processGO:0072593370.010
heart processGO:0003015570.010
rna metabolic processGO:00160704060.010
regulation of membrane potentialGO:00423911100.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
respiratory gaseous exchangeGO:000758540.010
l glutamate importGO:005193820.010
cellular response to external stimulusGO:00714961180.010
regulation of growthGO:00400081050.010
regulation of cell projection organizationGO:00313441750.010

P2ry12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
sensory system diseaseDOID:005015500.016
disease of metabolismDOID:001466700.013