Rattus norvegicus

21 known processes

Cyp4f5

cytochrome P450, family 4, subfamily f, polypeptide 5

Cyp4f5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.249
macromolecule localizationGO:00330362520.215
oxoacid metabolic processGO:00434362900.154
protein phosphorylationGO:00064683450.144
cellular component biogenesisGO:00440853680.140
cellular response to oxygen containing compoundGO:19017013860.137
single organism catabolic processGO:00447122830.131
response to metal ionGO:00100382530.131
cellular lipid metabolic processGO:00442552080.127
single organism biosynthetic processGO:00447113420.127
Rat
response to woundingGO:00096112540.121
catabolic processGO:00090563510.121
Rat
response to biotic stimulusGO:00096072260.117
tissue developmentGO:00098882520.116
regulation of phosphate metabolic processGO:00192203490.113
intracellular signal transductionGO:00355563140.111
anatomical structure morphogenesisGO:00096532980.106
response to inorganic substanceGO:00100353770.103
organonitrogen compound catabolic processGO:19015651790.098
organic substance catabolic processGO:19015753160.095
organic acid metabolic processGO:00060822920.094
cellular component assemblyGO:00226073600.092
regulation of protein modification processGO:00313991940.091
positive regulation of cell deathGO:00109421840.090
secretionGO:00469033070.090
intracellular transportGO:00469071850.088
lipid metabolic processGO:00066292830.087
regulation of molecular functionGO:00650093980.087
regulation of transcription dna templatedGO:00063553740.085
rna metabolic processGO:00160704060.085
regulation of nucleic acid templated transcriptionGO:19035063800.085
response to cytokineGO:00340972150.083
regulation of phosphorus metabolic processGO:00511743490.082
response to other organismGO:00517072200.081
nucleobase containing small molecule metabolic processGO:00550863160.081
protein localizationGO:00081041910.078
single organism intracellular transportGO:19025821660.078
cellular response to cytokine stimulusGO:00713451270.078
response to bacteriumGO:00096172000.076
neuron differentiationGO:00301823680.076
establishment of protein localizationGO:00451841410.075
central nervous system developmentGO:00074173110.075
cation transportGO:00068123820.074
reproductive processGO:00224143720.074
response to hypoxiaGO:00016662310.073
response to external biotic stimulusGO:00432072210.073
positive regulation of multicellular organismal processGO:00512403870.071
neurological system processGO:00508772190.069
regulation of cell proliferationGO:00421273590.069
positive regulation of signal transductionGO:00099671750.068
defense responseGO:00069521940.068
homeostatic processGO:00425923310.068
nucleic acid templated transcriptionGO:00976593790.067
aromatic compound catabolic processGO:00194391680.067
macromolecular complex subunit organizationGO:00439333390.067
positive regulation of response to stimulusGO:00485842850.066
apoptotic processGO:00069153810.065
regulation of homeostatic processGO:00328441010.064
multi organism reproductive processGO:00447032620.064
nitrogen compound transportGO:00717052290.064
cell projection organizationGO:00300303020.063
transcription dna templatedGO:00063513770.063
carbohydrate derivative metabolic processGO:19011353460.062
positive regulation of phosphate metabolic processGO:00459372620.062
ribonucleoside catabolic processGO:00424541260.062
regulation of apoptotic processGO:00429813350.062
response to acid chemicalGO:00011012220.062
positive regulation of catalytic activityGO:00430851840.061
cellular amino acid metabolic processGO:00065201070.060
neuron developmentGO:00486662860.060
regulation of protein metabolic processGO:00512462890.059
response to peptideGO:19016522920.059
regulation of cellular protein metabolic processGO:00322682670.059
regulation of rna metabolic processGO:00512523910.058
cellular component movementGO:00069282480.058
regulation of cellular ketone metabolic processGO:0010565270.058
protein transportGO:00150311320.057
macromolecular complex assemblyGO:00650032730.057
regulation of catalytic activityGO:00507903040.057
cellular catabolic processGO:00442482950.057
Rat
regulation of rna biosynthetic processGO:20011413810.056
nucleoside phosphate metabolic processGO:00067532830.056
regulation of intracellular signal transductionGO:19025312180.056
organic acid biosynthetic processGO:0016053830.055
Rat
rna biosynthetic processGO:00327743800.055
regulation of multicellular organismal developmentGO:20000263760.055
regulation of anatomical structure morphogenesisGO:00226031410.055
purine containing compound metabolic processGO:00725212530.054
organelle organizationGO:00069962660.053
small molecule biosynthetic processGO:00442831240.053
Rat
cellular ketone metabolic processGO:0042180510.053
regulation of signal transductionGO:00099663180.053
regulation of programmed cell deathGO:00430673410.052
organophosphate metabolic processGO:00196373700.052
agingGO:00075682410.051
regulation of secretionGO:00510462240.051
nucleoside metabolic processGO:00091161790.051
protein complex assemblyGO:00064612630.051
ion homeostasisGO:00508012120.050
nucleoside catabolic processGO:00091641260.050
regulation of kinase activityGO:00435491170.050
cellular response to hormone stimulusGO:00328702470.049
protein complex biogenesisGO:00702712630.049
positive regulation of developmental processGO:00510942830.049
cellular response to peptideGO:19016531330.049
immune system processGO:00023762040.048
positive regulation of programmed cell deathGO:00430681570.047
response to carbohydrateGO:00097431830.047
chemical homeostasisGO:00488782920.047
purine nucleoside catabolic processGO:00061521240.047
response to lipopolysaccharideGO:00324961910.047
response to ketoneGO:19016541820.046
Rat
lipid biosynthetic processGO:00086101280.046
brain developmentGO:00074202470.046
positive regulation of phosphorylationGO:00423271770.046
ribonucleoside metabolic processGO:00091191740.046
glycosyl compound catabolic processGO:19016581260.046
ribonucleotide catabolic processGO:00092611360.046
cellular nitrogen compound catabolic processGO:00442701630.045
locomotionGO:00400112370.045
glycosyl compound metabolic processGO:19016571820.045
purine ribonucleoside catabolic processGO:00461301240.045
organophosphate catabolic processGO:00464341480.044
renal system developmentGO:0072001670.044
Rat
cellular homeostasisGO:00197252520.044
response to decreased oxygen levelsGO:00362932370.044
signal transduction by phosphorylationGO:00230141440.044
positive regulation of cytosolic calcium ion concentrationGO:00072041220.044
cellular response to endogenous stimulusGO:00714953770.043
positive regulation of intracellular signal transductionGO:19025331380.043
transmembrane transportGO:00550854120.043
positive regulation of apoptotic processGO:00430651540.043
positive regulation of cell proliferationGO:00082842490.043
regulation of phosphorylationGO:00423252480.043
purine containing compound catabolic processGO:00725231380.042
positive regulation of protein metabolic processGO:00512471780.042
negative regulation of cellular metabolic processGO:00313242810.042
positive regulation of cellular protein metabolic processGO:00322701670.042
carbohydrate metabolic processGO:00059751300.041
cellular response to organonitrogen compoundGO:00714171970.041
positive regulation of cell communicationGO:00106472710.041
single organism organelle organizationGO:19025891800.041
response to insulinGO:00328681330.041
cellular response to peptide hormone stimulusGO:00713751200.041
cellular response to nitrogen compoundGO:19016992100.041
cytosolic calcium ion homeostasisGO:00514801400.040
head developmentGO:00603222470.040
nucleotide metabolic processGO:00091172790.040
nucleobase containing compound catabolic processGO:00346551520.040
negative regulation of nitrogen compound metabolic processGO:00511721610.040
reproductionGO:00000032450.040
response to oxygen levelsGO:00704822650.040
regulation of nervous system developmentGO:00519602640.040
cation homeostasisGO:00550801950.040
carbohydrate derivative catabolic processGO:19011361470.040
neuron projection developmentGO:00311752730.040
anion transportGO:00068201780.040
ribonucleoside triphosphate catabolic processGO:00092031220.039
localization of cellGO:00516742020.039
response to corticosteroidGO:00319602350.039
negative regulation of transportGO:00510511360.039
regulation of protein kinase activityGO:00458591050.039
g protein coupled receptor signaling pathwayGO:00071862420.039
positive regulation of protein phosphorylationGO:00019341350.039
negative regulation of multicellular organismal processGO:00512412030.038
positive regulation of phosphorus metabolic processGO:00105622620.038
regulation of cell differentiationGO:00455953200.038
heterocycle catabolic processGO:00467001670.038
multicellular organism reproductionGO:00325042330.037
organic cyclic compound catabolic processGO:19013611750.037
anatomical structure formation involved in morphogenesisGO:0048646830.037
response to hydrogen peroxideGO:0042542890.037
amine metabolic processGO:0009308380.037
regulation of protein phosphorylationGO:00019321830.037
negative regulation of macromolecule metabolic processGO:00106052600.036
response to estrogenGO:00436272320.036
response to transition metal nanoparticleGO:19902671220.036
ribonucleotide metabolic processGO:00092592310.036
metal ion homeostasisGO:00550651860.036
cellular response to lipopolysaccharideGO:0071222550.036
cellular response to biotic stimulusGO:0071216590.036
circulatory system developmentGO:00723591340.036
cellular chemical homeostasisGO:00550822470.035
response to temperature stimulusGO:0009266940.035
purine nucleoside metabolic processGO:00422781690.035
secretion by cellGO:00329402480.035
cell cell signalingGO:00072673350.035
cellular amine metabolic processGO:0044106380.035
nucleoside triphosphate metabolic processGO:00091411440.035
monocarboxylic acid metabolic processGO:00327871520.035
purine nucleoside triphosphate catabolic processGO:00091461220.035
response to extracellular stimulusGO:00099913800.035
regulation of cellular amine metabolic processGO:003323880.034
regulation of cellular component organizationGO:00511283680.034
cellular ion homeostasisGO:00068731840.034
cardiovascular system developmentGO:00723581340.034
behaviorGO:00076102050.033
nucleoside phosphate catabolic processGO:19012921400.033
b cell activation involved in immune responseGO:000231210.033
divalent inorganic cation homeostasisGO:00725071650.033
response to peptide hormoneGO:00434342780.033
purine ribonucleoside metabolic processGO:00461281680.033
cellular calcium ion homeostasisGO:00068741600.033
cellular response to stressGO:00335542690.032
regenerationGO:00310991630.032
nucleoside triphosphate catabolic processGO:00091431230.032
response to nutrientGO:00075842480.032
protein complex subunit organizationGO:00718223020.032
regulation of cellular localizationGO:00603412630.032
positive regulation of transportGO:00510502450.032
vesicle mediated transportGO:00161921810.032
cellular metal ion homeostasisGO:00068751720.031
cellular cation homeostasisGO:00300031800.031
cell motilityGO:00488702020.031
purine nucleotide metabolic processGO:00061632290.031
divalent metal ion transportGO:00708381320.031
multicellular organismal reproductive processGO:00486092330.031
cell type specific apoptotic processGO:00972851340.031
negative regulation of phosphorus metabolic processGO:0010563800.031
purine nucleotide catabolic processGO:00061951360.031
purine ribonucleotide metabolic processGO:00091502270.031
cellular macromolecule localizationGO:00707271220.031
leukocyte activationGO:0045321760.030
ribose phosphate metabolic processGO:00196932350.030
regulation of response to stressGO:00801341260.030
immune responseGO:00069551040.030
inflammatory responseGO:00069541500.030
cellular response to lipidGO:00713962010.030
negative regulation of biosynthetic processGO:00098901680.030
metal ion transportGO:00300012890.030
response to molecule of bacterial originGO:00022371940.030
sensory perceptionGO:00076001010.030
regulation of neurogenesisGO:00507672470.029
organic hydroxy compound metabolic processGO:19016151150.029
response to growth factorGO:00708481890.029
purine ribonucleotide catabolic processGO:00091541360.029
regulation of transferase activityGO:00513381230.029
angiogenesisGO:0001525530.029
regulation of neuron deathGO:19012141150.029
regulation of protein localizationGO:0032880810.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
positive regulation of mapk cascadeGO:0043410920.028
response to mechanical stimulusGO:00096121340.028
cellular divalent inorganic cation homeostasisGO:00725031620.028
programmed cell deathGO:00125013920.028
positive regulation of nitrogen compound metabolic processGO:00511733340.028
positive regulation of hydrolase activityGO:0051345860.028
single organism carbohydrate metabolic processGO:00447231180.028
circulatory system processGO:00030131830.028
ion transmembrane transportGO:00342203650.028
ribonucleoside triphosphate metabolic processGO:00091991410.028
response to radiationGO:00093141370.028
positive regulation of molecular functionGO:00440932300.028
response to organophosphorusGO:00466831020.028
mapk cascadeGO:00001651400.028
cytoplasmic transportGO:00164821150.027
regulation of cellular amino acid metabolic processGO:000652120.027
regulation of cell developmentGO:00602842630.027
regulation of hormone levelsGO:00108171870.027
response to glucocorticoidGO:00513842230.027
positive regulation of protein modification processGO:00314011420.027
cognitionGO:0050890920.027
regulation of membrane potentialGO:00423911100.027
developmental process involved in reproductionGO:00030061590.027
negative regulation of metabolic processGO:00098923310.027
negative regulation of cell communicationGO:00106481580.027
response to purine containing compoundGO:00140741260.027
biological adhesionGO:00226101100.027
regulation of hydrolase activityGO:00513361430.027
negative regulation of phosphate metabolic processGO:0045936800.026
purine nucleoside triphosphate metabolic processGO:00091441410.026
regulation of mapk cascadeGO:00434081160.026
forebrain developmentGO:0030900980.026
single organism reproductive processGO:00447022970.026
protein oligomerizationGO:00512591910.026
negative regulation of response to stimulusGO:00485851550.026
purine ribonucleoside triphosphate metabolic processGO:00092051400.026
calcium ion homeostasisGO:00550741620.026
regulation of secretion by cellGO:19035302080.025
response to oxidative stressGO:00069791860.025
neuron deathGO:00709971270.025
oxidation reduction processGO:00551143040.025
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
purine ribonucleoside triphosphate catabolic processGO:00092071220.025
vascular process in circulatory systemGO:0003018960.025
protein autophosphorylationGO:0046777660.025
membrane organizationGO:0061024940.025
positive regulation of cellular component organizationGO:00511302000.025
cellular protein localizationGO:00346131220.025
organophosphate biosynthetic processGO:00904071430.024
nucleotide catabolic processGO:00091661390.024
ras protein signal transductionGO:0007265290.024
carboxylic acid biosynthetic processGO:0046394830.024
Rat
synaptic transmissionGO:00072682350.024
fatty acid metabolic processGO:0006631990.024
regulation of metal ion transportGO:00109591180.024
rhythmic processGO:00485111560.024
positive regulation of signalingGO:00230562700.024
positive regulation of cell differentiationGO:00455972170.024
regulation of ion transportGO:00432692450.024
regulation of response to external stimulusGO:00321011060.024
organic anion transportGO:00157111320.024
vasculature developmentGO:0001944700.023
positive regulation of nervous system developmentGO:00519621780.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
carboxylic acid transportGO:00469421150.023
muscle system processGO:00030121150.023
cellular response to tumor necrosis factorGO:0071356460.023
positive regulation of cell developmentGO:00107201760.023
response to reactive oxygen speciesGO:00003021200.023
eye morphogenesisGO:004859240.023
positive regulation of cellular biosynthetic processGO:00313282950.023
blood circulationGO:00080151830.023
dna metabolic processGO:0006259960.023
peptidyl amino acid modificationGO:00181931260.023
negative regulation of protein metabolic processGO:00512481140.023
negative regulation of signalingGO:00230571570.022
negative regulation of cell deathGO:00605482290.022
peptidyl tyrosine phosphorylationGO:0018108720.022
single organism membrane organizationGO:0044802740.022
gastrulationGO:000736920.022
organic acid transportGO:00158491160.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
regulation of blood vessel sizeGO:0050880890.022
organonitrogen compound biosynthetic processGO:19015661670.022
regulation of cellular component movementGO:00512701500.022
response to nutrient levelsGO:00316673700.022
response to monosaccharideGO:00342841590.022
cytokine productionGO:0001816610.022
divalent inorganic cation transportGO:00725111340.022
positive regulation of kinase activityGO:0033674770.022
regulation of system processGO:00440572080.022
wound healingGO:00420601220.022
regulation of neuron differentiationGO:00456642080.021
learning or memoryGO:0007611900.021
regulation of establishment of protein localizationGO:0070201690.021
negative regulation of protein phosphorylationGO:0001933440.021
transcription from rna polymerase ii promoterGO:00063662520.021
regulation of cell motilityGO:20001451310.021
positive regulation of secretionGO:00510471400.021
action potentialGO:0001508540.021
cell migrationGO:00164771970.021
negative regulation of innate immune responseGO:004582440.021
regulation of cell migrationGO:00303341280.021
negative regulation of gene expressionGO:00106291990.020
monovalent inorganic cation transportGO:00156721720.020
endocytosisGO:0006897840.020
unsaturated fatty acid metabolic processGO:0033559390.020
regulation of immune system processGO:00026821230.020
regulation of protein secretionGO:0050708280.020
b cell differentiationGO:003018320.020
cell adhesionGO:00071551100.020
positive regulation of cell projection organizationGO:00313461110.019
response to estradiolGO:00323551640.019
positive regulation of protein kinase activityGO:0045860730.019
response to amino acidGO:0043200750.019
cellular response to molecule of bacterial originGO:0071219560.019
intracellular protein transportGO:0006886790.019
response to alkaloidGO:00432791320.019
small gtpase mediated signal transductionGO:0007264360.019
response to hexoseGO:00097461440.019
urogenital system developmentGO:0001655780.019
Rat
single organism cellular localizationGO:19025801020.019
cellular response to organic cyclic compoundGO:00714072020.019
axis specificationGO:000979840.019
anterior posterior pattern specificationGO:000995210.019
regulation of purine nucleotide metabolic processGO:19005421150.019
gliogenesisGO:0042063930.019
blood vessel morphogenesisGO:0048514580.019
calcium ion transportGO:00068161310.019
positive regulation of gene expressionGO:00106282440.018
cofactor metabolic processGO:0051186950.018
gtp catabolic processGO:0006184710.018
response to ionizing radiationGO:0010212590.018
sexual reproductionGO:00199531480.018
heart morphogenesisGO:000300730.018
immunoglobulin mediated immune responseGO:001606440.018
immune effector processGO:0002252530.018
actin filament based processGO:0030029860.018
regulation of cellular catabolic processGO:00313291010.018
negative regulation of programmed cell deathGO:00430691830.018
negative regulation of immune system processGO:0002683390.018
cell morphogenesisGO:00009021420.018
cation transmembrane transportGO:00986552630.018
negative regulation of apoptotic processGO:00430661810.018
protein homooligomerizationGO:0051260910.017
positive regulation of neurogenesisGO:00507691650.017
negative regulation of transcription dna templatedGO:00458921160.017
positive regulation of transferase activityGO:0051347810.017
embryonic pattern specificationGO:000988010.017
negative regulation of molecular functionGO:00440921330.017
cellular response to external stimulusGO:00714961180.017
positive regulation of immune system processGO:0002684900.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
single organism behaviorGO:00447081300.017
negative regulation of secretionGO:0051048820.017
regulation of synaptic transmissionGO:00508041410.017
epithelium developmentGO:0060429960.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
positive regulation of rna metabolic processGO:00512542030.017
cell activationGO:0001775970.017
positive regulation of secretion by cellGO:19035321280.016
alcohol metabolic processGO:0006066770.016
regulation of locomotionGO:00400121480.016
regulation of catabolic processGO:00098941130.016
amide transportGO:00428861050.016
guanosine containing compound metabolic processGO:1901068740.016
protein secretionGO:0009306340.016
tube developmentGO:0035295890.016
response to tumor necrosis factorGO:0034612560.016
cytoskeleton organizationGO:00070101110.016
regulation of anatomical structure sizeGO:00900661350.016
response to toxic substanceGO:00096361330.016
Rat
regulation of immune responseGO:0050776550.016
programmed necrotic cell deathGO:009730020.016
regulation of protein transportGO:0051223680.016
regulation of immunoglobulin secretionGO:005102310.015
gtp metabolic processGO:0046039720.015
transmission of nerve impulseGO:0019226420.015
positive regulation of isotype switchingGO:004583010.015
positive regulation of rna biosynthetic processGO:19026801970.015
acrosome assemblyGO:000167530.015
negative regulation of cellular biosynthetic processGO:00313271610.015
regulation of neuron projection developmentGO:00109751610.015
positive regulation of cellular amine metabolic processGO:003324030.015
positive regulation of biosynthetic processGO:00098913190.015
hormone metabolic processGO:0042445690.015
cellular response to insulin stimulusGO:0032869810.015
gamete generationGO:00072761240.015
kidney developmentGO:0001822670.015
Rat
regulation of cytokine productionGO:0001817560.015
negative regulation of cellular protein metabolic processGO:00322691060.015
negative regulation of homeostatic processGO:0032845470.015
peptidyl tyrosine modificationGO:0018212720.015
muscle contractionGO:0006936880.015
response to glucoseGO:00097491360.015
negative regulation of neurogenesisGO:0050768780.015
tumor necrosis factor mediated signaling pathwayGO:003320940.015
cellular response to growth factor stimulusGO:00713631620.015
organ morphogenesisGO:0009887750.014
response to interleukin 1GO:0070555550.014
multi multicellular organism processGO:00447061380.014
negative regulation of developmental processGO:00510931250.014
positive regulation of transcription dna templatedGO:00458931970.014
circadian rhythmGO:0007623880.014
regulation of map kinase activityGO:0043405530.014
cellular component morphogenesisGO:00329891550.014
positive regulation of nucleoside metabolic processGO:0045979550.014
peptide transportGO:0015833970.014
regulation of blood pressureGO:0008217830.014
positive regulation of cytokine productionGO:0001819420.014
response to retinoic acidGO:0032526630.014
axon developmentGO:0061564960.014
regulation of gtpase activityGO:0043087570.014
limb morphogenesisGO:003510840.014
growthGO:00400071650.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.014
maintenance of locationGO:0051235170.014
mesoderm developmentGO:000749820.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
fatty acid derivative metabolic processGO:1901568380.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
appendage morphogenesisGO:003510740.014
regulation of immunoglobulin productionGO:000263740.014
cellular response to acid chemicalGO:0071229750.013
telencephalon developmentGO:0021537620.013
chromosome segregationGO:000705920.013
positive regulation of locomotionGO:00400171020.013
positive regulation of protein transportGO:0051222410.013
coenzyme metabolic processGO:0006732860.013
protein targetingGO:0006605610.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
negative regulation of cellular component organizationGO:0051129830.013
negative regulation of cell differentiationGO:0045596990.013
positive regulation of gtpase activityGO:0043547470.013
regulation of protein serine threonine kinase activityGO:0071900640.013
positive regulation of angiogenesisGO:0045766280.013
activation of cysteine type endopeptidase activityGO:009720240.013
regulation of cell projection organizationGO:00313441750.013
multicellular organism growthGO:003526410.013
positive regulation of immunoglobulin productionGO:000263940.013
response to calcium ionGO:0051592590.013
sex differentiationGO:00075481130.013
regulation of nucleotide metabolic processGO:00061401170.013
dephosphorylationGO:0016311980.013
negative regulation of phosphorylationGO:0042326570.013
negative regulation of catalytic activityGO:00430861030.013
positive regulation of erk1 and erk2 cascadeGO:0070374290.013
negative regulation of collagen biosynthetic processGO:003296640.013

Cyp4f5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.022
disease of anatomical entityDOID:700.022
kidney diseaseDOID:55700.017
urinary system diseaseDOID:1800.017
disease of metabolismDOID:001466700.014
central nervous system diseaseDOID:33100.013