Rattus norvegicus

129 known processes

Hes5

hairy and enhancer of split 5 (Drosophila)

Hes5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000263760.444
regulation of neuron differentiationGO:00456642080.311
regulation of cell developmentGO:00602842630.309
regulation of secretionGO:00510462240.241
central nervous system developmentGO:00074173110.221
brain developmentGO:00074202470.173
response to metal ionGO:00100382530.165
head developmentGO:00603222470.162
negative regulation of nitrogen compound metabolic processGO:00511721610.145
response to inorganic substanceGO:00100353770.144
positive regulation of nervous system developmentGO:00519621780.136
Fly
negative regulation of cell developmentGO:0010721820.134
neuron differentiationGO:00301823680.115
regulation of phosphorus metabolic processGO:00511743490.109
Mouse
regulation of intracellular signal transductionGO:19025312180.107
Mouse
secretionGO:00469033070.095
circulatory system processGO:00030131830.095
response to nutrient levelsGO:00316673700.094
gliogenesisGO:0042063930.092
regulation of ion transportGO:00432692450.091
transmembrane transportGO:00550854120.086
negative regulation of biosynthetic processGO:00098901680.084
locomotionGO:00400112370.083
Fly
carboxylic acid transportGO:00469421150.079
negative regulation of neuron differentiationGO:0045665620.076
oxoacid metabolic processGO:00434362900.075
cation homeostasisGO:00550801950.075
negative regulation of cell differentiationGO:0045596990.070
positive regulation of neurogenesisGO:00507691650.069
Fly
positive regulation of cell developmentGO:00107201760.067
Fly
cation transportGO:00068123820.066
epithelial cell differentiationGO:0030855710.065
Mouse Worm
regulation of neural precursor cell proliferationGO:2000177160.064
Fly
blood circulationGO:00080151830.063
cellular amino acid metabolic processGO:00065201070.063
regulation of cell differentiationGO:00455953200.062
negative regulation of macromolecule biosynthetic processGO:00105581480.062
vesicle mediated transportGO:00161921810.062
positive regulation of cell differentiationGO:00455972170.061
Fly
positive regulation of cell proliferationGO:00082842490.059
Human Fly
positive regulation of macromolecule biosynthetic processGO:00105572470.058
Mouse
nucleoside metabolic processGO:00091161790.058
negative regulation of multicellular organismal processGO:00512412030.058
positive regulation of nucleic acid templated transcriptionGO:19035081970.056
Mouse
regulation of neurogenesisGO:00507672470.055
transcription dna templatedGO:00063513770.055
heart morphogenesisGO:000300730.054
localization of cellGO:00516742020.054
carbohydrate derivative metabolic processGO:19011353460.054
transcription from rna polymerase ii promoterGO:00063662520.054
positive regulation of rna metabolic processGO:00512542030.052
Mouse
organophosphate metabolic processGO:00196373700.051
negative regulation of neurogenesisGO:0050768780.050
negative regulation of transcription regulatory region dna bindingGO:200067820.049
regulation of purine nucleotide metabolic processGO:19005421150.049
nucleobase containing small molecule metabolic processGO:00550863160.049
single organism reproductive processGO:00447022970.048
positive regulation of transportGO:00510502450.048
response to acid chemicalGO:00011012220.048
immune system processGO:00023762040.047
regulation of nervous system developmentGO:00519602640.047
anatomical structure morphogenesisGO:00096532980.046
Zebrafish Mouse Worm Fly
synaptic transmissionGO:00072682350.045
cell motilityGO:00488702020.045
response to hexoseGO:00097461440.045
glial cell differentiationGO:0010001650.044
regulation of nucleic acid templated transcriptionGO:19035063800.044
positive regulation of neuron projection developmentGO:0010976990.044
regulation of cell projection organizationGO:00313441750.044
sulfur compound metabolic processGO:0006790700.044
cellular response to lipidGO:00713962010.043
protein complex assemblyGO:00064612630.043
Mouse
cellular component movementGO:00069282480.042
cell projection organizationGO:00300303020.042
Zebrafish Fly
positive regulation of hydrolase activityGO:0051345860.042
calcium ion transportGO:00068161310.042
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.041
Mouse
positive regulation of developmental processGO:00510942830.041
Fly
negative regulation of nervous system developmentGO:0051961790.041
purine nucleoside triphosphate metabolic processGO:00091441410.040
renal system developmentGO:0072001670.040
Mouse
embryonic skeletal system morphogenesisGO:004870430.039
regulation of vesicle mediated transportGO:0060627810.039
catabolic processGO:00090563510.039
rna biosynthetic processGO:00327743800.039
organic substance catabolic processGO:19015753160.039
positive regulation of phosphorus metabolic processGO:00105622620.039
Mouse
nucleic acid templated transcriptionGO:00976593790.039
cellular response to organic cyclic compoundGO:00714072020.038
negative regulation of nucleic acid templated transcriptionGO:19035071170.038
ribonucleoside metabolic processGO:00091191740.037
epithelium developmentGO:0060429960.037
Zebrafish Mouse Worm
negative regulation of metabolic processGO:00098923310.037
response to extracellular stimulusGO:00099913800.037
regulation of neuron projection developmentGO:00109751610.036
tissue developmentGO:00098882520.036
Human Zebrafish Mouse Worm Fly
response to hypoxiaGO:00016662310.036
macromolecular complex subunit organizationGO:00439333390.036
Mouse
programmed cell deathGO:00125013920.036
positive regulation of intracellular signal transductionGO:19025331380.036
Mouse
neurological system processGO:00508772190.035
Mouse Fly
reproductive processGO:00224143720.035
Worm
organic acid transportGO:00158491160.035
purine ribonucleotide metabolic processGO:00091502270.035
kidney developmentGO:0001822670.035
Mouse
protein complex biogenesisGO:00702712630.035
Mouse
homeostatic processGO:00425923310.034
ribose phosphate metabolic processGO:00196932350.034
neuron developmentGO:00486662860.034
Zebrafish Fly
positive regulation of cellular component organizationGO:00511302000.034
positive regulation of multicellular organismal processGO:00512403870.033
Fly
divalent inorganic cation transportGO:00725111340.033
regulation of immune system processGO:00026821230.032
secretion by cellGO:00329402480.032
positive regulation of cell projection organizationGO:00313461110.031
embryonic skeletal system developmentGO:004870630.031
apoptotic processGO:00069153810.031
purine ribonucleoside metabolic processGO:00461281680.031
tube formationGO:003514830.031
Mouse
divalent metal ion transportGO:00708381320.030
cellular response to abiotic stimulusGO:0071214850.030
intracellular signal transductionGO:00355563140.030
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.030
nucleobase containing compound catabolic processGO:00346551520.030
negative regulation of transcription dna templatedGO:00458921160.029
cellular response to nitrogen compoundGO:19016992100.029
membrane organizationGO:0061024940.029
response to amino acidGO:0043200750.029
positive regulation of signal transductionGO:00099671750.029
Mouse
negative regulation of cellular metabolic processGO:00313242810.029
urogenital system developmentGO:0001655780.028
Mouse
purine nucleotide metabolic processGO:00061632290.028
protein tetramerizationGO:0051262380.028
positive regulation of neuron differentiationGO:00456661260.028
macromolecule localizationGO:00330362520.027
embryonic cranial skeleton morphogenesisGO:004870120.027
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.027
cellular chemical homeostasisGO:00550822470.027
response to calcium ionGO:0051592590.027
mesonephros developmentGO:0001823140.027
regulation of molecular functionGO:00650093980.027
cellular modified amino acid metabolic processGO:0006575610.027
organic acid metabolic processGO:00060822920.026
cellular component biogenesisGO:00440853680.026
Mouse
organ morphogenesisGO:0009887750.026
Mouse Fly
cell morphogenesis involved in differentiationGO:00009041190.026
Zebrafish Fly
positive regulation of catalytic activityGO:00430851840.026
positive regulation of nitrogen compound metabolic processGO:00511733340.026
Mouse
regulation of signal transductionGO:00099663180.026
Mouse
positive regulation of gene expressionGO:00106282440.026
Mouse
ribonucleotide metabolic processGO:00092592310.026
response to glucocorticoidGO:00513842230.026
detection of visible lightGO:000958430.025
regulation of rna metabolic processGO:00512523910.025
organonitrogen compound biosynthetic processGO:19015661670.025
response to woundingGO:00096112540.025
cell migrationGO:00164771970.025
regulation of protein modification processGO:00313991940.025
Mouse
glycosyl compound metabolic processGO:19016571820.025
positive regulation of rna biosynthetic processGO:19026801970.025
Mouse
cellular cation homeostasisGO:00300031800.025
positive regulation of cellular biosynthetic processGO:00313282950.025
Mouse
diencephalon developmentGO:0021536210.024
positive regulation of immune system processGO:0002684900.024
rna metabolic processGO:00160704060.024
regulation of cellular component organizationGO:00511283680.024
purine nucleoside metabolic processGO:00422781690.024
negative regulation of rna metabolic processGO:00512531230.024
positive regulation of phosphate metabolic processGO:00459372620.024
Mouse
protein oligomerizationGO:00512591910.023
metal ion transportGO:00300012890.023
response to cytokineGO:00340972150.023
regulation of hydrolase activityGO:00513361430.023
negative regulation of cellular biosynthetic processGO:00313271610.023
cardiac chamber developmentGO:000320510.023
cell adhesionGO:00071551100.023
Mouse
response to vitaminGO:00332731310.023
regulation of cellular ketone metabolic processGO:0010565270.023
regulation of canonical wnt signaling pathwayGO:006082840.023
positive regulation of secretionGO:00510471400.022
male gonad developmentGO:0008584590.022
ras protein signal transductionGO:0007265290.021
dephosphorylationGO:0016311980.021
regulation of catalytic activityGO:00507903040.021
development of primary sexual characteristicsGO:00451371070.021
response to corticosteroidGO:00319602350.021
response to alkaloidGO:00432791320.021
amino acid transportGO:0006865700.021
positive regulation of transcription dna templatedGO:00458931970.021
Mouse
regulation of synaptic transmissionGO:00508041410.021
protein transportGO:00150311320.021
organophosphate biosynthetic processGO:00904071430.021
positive regulation of molecular functionGO:00440932300.021
response to molecule of bacterial originGO:00022371940.021
negative regulation of cell deathGO:00605482290.021
positive regulation of gtp catabolic processGO:0033126480.021
chemical homeostasisGO:00488782920.021
acid secretionGO:0046717480.020
telencephalon developmentGO:0021537620.020
Mouse
nucleoside phosphate metabolic processGO:00067532830.020
cellular calcium ion homeostasisGO:00068741600.020
positive regulation of response to stimulusGO:00485842850.020
Mouse
cell morphogenesisGO:00009021420.020
Zebrafish Fly
cellular response to endogenous stimulusGO:00714953770.020
cardiac ventricle developmentGO:000323110.020
eye morphogenesisGO:004859240.020
Fly
negative regulation of transportGO:00510511360.019
hematopoietic or lymphoid organ developmentGO:0048534360.019
mesenchymal to epithelial transitionGO:006023130.019
response to decreased oxygen levelsGO:00362932370.019
muscle organ morphogenesisGO:004864410.019
cellular nitrogen compound catabolic processGO:00442701630.019
divalent inorganic cation homeostasisGO:00725071650.019
organic hydroxy compound metabolic processGO:19016151150.019
skeletal system developmentGO:0001501410.019
Human Mouse
positive regulation of amine transportGO:0051954260.018
ribonucleoside triphosphate metabolic processGO:00091991410.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
Mouse
reproductionGO:00000032450.018
protein complex subunit organizationGO:00718223020.018
Mouse
regulation of transcription regulatory region dna bindingGO:200067740.018
guanosine containing compound metabolic processGO:1901068740.018
response to growth factorGO:00708481890.018
nucleoside triphosphate metabolic processGO:00091411440.018
forebrain developmentGO:0030900980.017
intracellular protein transportGO:0006886790.017
negative regulation of synaptic transmission dopaminergicGO:003222740.017
neuron deathGO:00709971270.017
hematopoietic progenitor cell differentiationGO:000224420.017
cellular catabolic processGO:00442482950.017
eye developmentGO:0001654500.017
Zebrafish Mouse Fly
regulation of phosphate metabolic processGO:00192203490.017
Mouse
intracellular transportGO:00469071850.017
regulation of nucleotide metabolic processGO:00061401170.017
purine nucleotide catabolic processGO:00061951360.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.017
learning or memoryGO:0007611900.017
response to ethanolGO:00454711620.017
regulation of calcium ion transportGO:0051924770.017
regulation of behaviorGO:0050795610.017
nucleoside phosphate catabolic processGO:19012921400.017
cellular response to cgmpGO:007132120.017
regulation of transcription dna templatedGO:00063553740.017
protein localizationGO:00081041910.017
pancreas developmentGO:0031016190.016
negative regulation of response to stimulusGO:00485851550.016
tissue morphogenesisGO:0048729220.016
Mouse
regulation of stem cell proliferationGO:0072091140.016
Fly
positive regulation of signalingGO:00230562700.016
Mouse
regulation of cell proliferationGO:00421273590.016
Human Fly
muscle organ developmentGO:0007517500.016
action potentialGO:0001508540.016
Mouse
immune system developmentGO:0002520410.016
regulation of response to stressGO:00801341260.016
Fly
thyroid gland developmentGO:003087810.016
response to mechanical stimulusGO:00096121340.016
nucleotide metabolic processGO:00091172790.016
exocytosisGO:0006887600.016
ossificationGO:0001503700.016
regulation of apoptotic processGO:00429813350.016
biological adhesionGO:00226101100.016
Mouse
multicellular organism reproductionGO:00325042330.016
anion transportGO:00068201780.016
cell proliferation in external granule layerGO:002192410.016
striated muscle tissue developmentGO:0014706580.016
response to peptideGO:19016522920.016
positive regulation of purine nucleotide metabolic processGO:1900544910.016
hepaticobiliary system developmentGO:0061008900.015
carbohydrate derivative catabolic processGO:19011361470.015
cellular macromolecule localizationGO:00707271220.015
cellular homeostasisGO:00197252520.015
morphogenesis of embryonic epitheliumGO:001633130.015
Mouse
dendrite developmentGO:0016358720.015
Fly
endocrine system developmentGO:0035270300.015
regulation of locomotionGO:00400121480.015
detection of stimulusGO:0051606240.015
developmental maturationGO:0021700250.015
Mouse
negative regulation of defecationGO:200029310.015
regulation of neuron apoptotic processGO:0043523830.015
response to cgmpGO:007030530.015
negative regulation of developmental processGO:00510931250.015
cellular protein localizationGO:00346131220.014
single organism behaviorGO:00447081300.014
single organism membrane organizationGO:0044802740.014
ribonucleoside catabolic processGO:00424541260.014
metal ion homeostasisGO:00550651860.014
protein phosphorylationGO:00064683450.014
Mouse
purine containing compound catabolic processGO:00725231380.014
regulation of programmed cell deathGO:00430673410.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
axon developmentGO:0061564960.014
Zebrafish
positive regulation of phosphorylationGO:00423271770.014
Mouse
muscle tissue morphogenesisGO:006041510.014
single organism catabolic processGO:00447122830.014
regulation of system processGO:00440572080.014
single organism intracellular transportGO:19025821660.014
negative regulation of programmed cell deathGO:00430691830.014
positive regulation of cellular amine metabolic processGO:003324030.014
nucleotide catabolic processGO:00091661390.014
regulation of cellular localizationGO:00603412630.014
myeloid leukocyte differentiationGO:0002573200.014
positive regulation of secretion by cellGO:19035321280.014
carbohydrate metabolic processGO:00059751300.014
regulation of protein metabolic processGO:00512462890.014
Mouse
metanephros developmentGO:0001656140.014
Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
response to ammonium ionGO:0060359710.014
defense responseGO:00069521940.014
cellular response to growth factor stimulusGO:00713631620.013
response to oxygen levelsGO:00704822650.013
establishment of protein localizationGO:00451841410.013
leukocyte differentiationGO:0002521300.013
palate developmentGO:006002120.013
regulation of small gtpase mediated signal transductionGO:0051056480.013
regulation of nucleoside metabolic processGO:0009118660.013
cation transmembrane transportGO:00986552630.013
carboxylic acid metabolic processGO:00197522890.013
circulatory system developmentGO:00723591340.013
regulation of anatomical structure morphogenesisGO:00226031410.013
forebrain generation of neuronsGO:002187280.013
multicellular organismal reproductive processGO:00486092330.013
lymphoid progenitor cell differentiationGO:000232020.013
response to glucoseGO:00097491360.013
osteoblast differentiationGO:0001649260.013
s shaped body morphogenesisGO:007205020.013
Mouse
organonitrogen compound catabolic processGO:19015651790.013
cell part morphogenesisGO:00329901230.013
Zebrafish Fly
cellular component assemblyGO:00226073600.013
Mouse
positive regulation of erk1 and erk2 cascadeGO:0070374290.013
aromatic compound catabolic processGO:00194391680.013
reproductive structure developmentGO:00486081280.012
negative regulation of gene expressionGO:00106291990.012
response to ketoneGO:19016541820.012
regulation of anion transportGO:0044070430.012
regulation of catabolic processGO:00098941130.012
ion homeostasisGO:00508012120.012
phenol containing compound metabolic processGO:0018958300.012
regulation of cellular amine metabolic processGO:003323880.012
muscle structure developmentGO:0061061870.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
Zebrafish Fly
rhythmic processGO:00485111560.012
positive regulation of biosynthetic processGO:00098913190.012
Mouse
liver developmentGO:0001889900.012
cell cell signalingGO:00072673350.012
regulation of rna biosynthetic processGO:20011413810.012
autonomic nervous system developmentGO:004848330.012
glycerolipid metabolic processGO:0046486670.012
regulation of protein transportGO:0051223680.012
purine ribonucleoside catabolic processGO:00461301240.012
positive regulation of cell communicationGO:00106472710.012
Mouse
purine nucleoside triphosphate catabolic processGO:00091461220.012
regulation of metal ion transportGO:00109591180.012
regulation of cellular catabolic processGO:00313291010.012
inner ear receptor cell differentiationGO:006011320.012
Mouse
response to nutrientGO:00075842480.012
cellular response to alcoholGO:0097306870.012
triglyceride homeostasisGO:007032820.012
liver morphogenesisGO:007257630.012
glycosyl compound catabolic processGO:19016581260.012
neural crest cell developmentGO:001403220.012
ureteric bud developmentGO:0001657140.011
regulation of tube sizeGO:0035150890.011
kidney epithelium developmentGO:0072073190.011
Mouse
tube developmentGO:0035295890.011
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
cellular component morphogenesisGO:00329891550.011
Zebrafish Fly
cellular response to oxygen containing compoundGO:19017013860.011
regulation of response to woundingGO:1903034690.011
cerebellar granule cell precursor proliferationGO:002193010.011
calcium ion transmembrane transportGO:0070588700.011
regulation of camp biosynthetic processGO:0030817380.011
positive regulation of nucleotide metabolic processGO:0045981910.011
gland developmentGO:00487321550.011
gtp catabolic processGO:0006184710.011
neuroepithelial cell differentiationGO:006056320.011
regulation of peptide hormone secretionGO:0090276800.011
peptide transportGO:0015833970.011
neural crest cell migrationGO:000175510.011
purine ribonucleotide catabolic processGO:00091541360.011
negative regulation of molecular functionGO:00440921330.011
positive regulation of intracellular transportGO:0032388390.011
regulation of neurotransmitter levelsGO:0001505420.011
organic anion transportGO:00157111320.011
skin developmentGO:0043588170.011
Mouse Worm
nucleotide biosynthetic processGO:0009165980.011
gamete generationGO:00072761240.011
vascular process in circulatory systemGO:0003018960.011
sensory perceptionGO:00076001010.011
negative regulation of cellular component organizationGO:0051129830.011
mesonephric tubule developmentGO:0072164140.011
amide transportGO:00428861050.011
response to dexamethasoneGO:0071548490.010
macromolecular complex assemblyGO:00650032730.010
Mouse
neurotransmitter uptakeGO:000150430.010
nucleoside catabolic processGO:00091641260.010
neuron projection morphogenesisGO:00488121220.010
Zebrafish Fly
dicarboxylic acid transportGO:0006835340.010
regulation of gtpase activityGO:0043087570.010
regulation of secretion by cellGO:19035302080.010
cellular ion homeostasisGO:00068731840.010
organophosphate catabolic processGO:00464341480.010
gastrulationGO:000736920.010
regulation of homeostatic processGO:00328441010.010
signal releaseGO:00230611450.010
regulation of establishment of protein localizationGO:0070201690.010
negative regulation of ion transportGO:0043271510.010
regulation of phosphorylationGO:00423252480.010
Mouse
regulation of mapk cascadeGO:00434081160.010
developmental programmed cell deathGO:001062320.010
regulation of gtp catabolic processGO:0033124580.010
axonogenesisGO:0007409710.010
Zebrafish
regulation of metanephros developmentGO:007221540.010
regulation of reactive oxygen species metabolic processGO:2000377260.010
cellular amine metabolic processGO:0044106380.010

Hes5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
gastrointestinal system diseaseDOID:7700.042
nervous system diseaseDOID:86300.027
sensory system diseaseDOID:005015500.021
eye and adnexa diseaseDOID:149200.019
eye diseaseDOID:561400.019
musculoskeletal system diseaseDOID:1700.017
heart diseaseDOID:11400.015
cardiovascular system diseaseDOID:128700.015
retinal diseaseDOID:567900.013
retinal degenerationDOID:846600.013
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011