Rattus norvegicus

0 known processes

Ier2

immediate early response 2

(Aliases: MGC72578)

Ier2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
bmp signaling pathwayGO:003050940.884
inactivation of mapk activityGO:000018820.775
cellular response to follicle stimulating hormone stimulusGO:0071372130.748
negative regulation of rna metabolic processGO:00512531230.710
regulation of rna biosynthetic processGO:20011413810.705
rna metabolic processGO:00160704060.677
nucleic acid templated transcriptionGO:00976593790.675
cellular response to mycophenolic acidGO:007150620.636
rna biosynthetic processGO:00327743800.586
positive regulation of neuron apoptotic processGO:0043525330.541
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.540
negative regulation of cellular biosynthetic processGO:00313271610.517
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.514
positive regulation of apoptotic processGO:00430651540.508
regulation of nucleic acid templated transcriptionGO:19035063800.505
regulation of transcription dna templatedGO:00063553740.499
regulation of transcription from rna polymerase ii promoterGO:00063572340.494
regulation of rna metabolic processGO:00512523910.481
negative regulation of nucleobase containing compound metabolic processGO:00459341530.439
negative regulation of nitrogen compound metabolic processGO:00511721610.415
regulation of metanephros developmentGO:007221540.402
transcription from rna polymerase ii promoterGO:00063662520.392
skeletal muscle cell differentiationGO:003591420.384
negative regulation of macromolecule biosynthetic processGO:00105581480.369
negative regulation of gene expressionGO:00106291990.353
transcription dna templatedGO:00063513770.347
response to campGO:0051591910.330
negative regulation of nucleic acid templated transcriptionGO:19035071170.315
negative regulation of biosynthetic processGO:00098901680.315
negative regulation of metabolic processGO:00098923310.268
negative regulation of transcription dna templatedGO:00458921160.261
regulation of apoptotic processGO:00429813350.259
negative regulation of macromolecule metabolic processGO:00106052600.243
interleukin 1 mediated signaling pathwayGO:007049820.243
negative regulation of apoptotic processGO:00430661810.241
regulation of signal transductionGO:00099663180.234
regulation of multicellular organismal developmentGO:20000263760.233
cellular response to cycloheximideGO:007140940.227
cellular response to cytokine stimulusGO:00713451270.211
regulation of cellular protein metabolic processGO:00322682670.210
negative regulation of cellular metabolic processGO:00313242810.199
cellular response to isoquinoline alkaloidGO:007131760.193
negative regulation of rna biosynthetic processGO:19026791180.186
regulation of phosphate metabolic processGO:00192203490.183
positive regulation of programmed cell deathGO:00430681570.172
positive regulation of myeloid leukocyte differentiationGO:000276370.171
tube developmentGO:0035295890.167
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.157
negative regulation of phosphorus metabolic processGO:0010563800.154
positive regulation of metanephric glomerulus developmentGO:007230010.153
negative regulation of canonical wnt signaling pathwayGO:009009040.153
protein phosphorylationGO:00064683450.151
regulation of protein modification processGO:00313991940.151
positive regulation of multicellular organismal processGO:00512403870.147
response to peptideGO:19016522920.146
regulation of protein metabolic processGO:00512462890.135
embryonic skeletal system morphogenesisGO:004870430.135
programmed cell deathGO:00125013920.132
collateral sproutingGO:004866820.132
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.130
regulation of programmed cell deathGO:00430673410.129
regulation of protein kinase activityGO:00458591050.128
mapk cascadeGO:00001651400.124
positive regulation of rna metabolic processGO:00512542030.124
leukocyte differentiationGO:0002521300.123
response to gamma radiationGO:0010332240.121
response to organophosphorusGO:00466831020.120
cell proliferation involved in metanephros developmentGO:007220320.118
cellular response to endogenous stimulusGO:00714953770.116
cellular response to stressGO:00335542690.112
regulation of molecular functionGO:00650093980.110
central nervous system developmentGO:00074173110.108
conditioned taste aversionGO:000166120.107
response to heparinGO:007150320.105
response to purine containing compoundGO:00140741260.100
cellular response to hormone stimulusGO:00328702470.100
carbohydrate derivative metabolic processGO:19011353460.099
positive regulation of neuron deathGO:1901216430.098
apoptotic processGO:00069153810.094
anatomical structure morphogenesisGO:00096532980.094
regulation of phosphorus metabolic processGO:00511743490.094
response to acid chemicalGO:00011012220.093
cytokine mediated signaling pathwayGO:0019221430.092
long term synaptic potentiationGO:0060291210.092
regulation of cell proliferationGO:00421273590.092
positive regulation of cell proliferationGO:00082842490.089
response to amphetamineGO:0001975250.087
intracellular signal transductionGO:00355563140.086
negative regulation of programmed cell deathGO:00430691830.085
response to decreased oxygen levelsGO:00362932370.084
positive regulation of cell deathGO:00109421840.083
circulatory system developmentGO:00723591340.082
cell proliferation involved in kidney developmentGO:007211150.081
transforming growth factor beta receptor signaling pathwayGO:0007179180.081
positive regulation of nitrogen compound metabolic processGO:00511733340.080
glomerular mesangial cell proliferationGO:007211040.080
negative regulation of mapk cascadeGO:0043409200.079
response to catecholamineGO:0071869160.078
response to extracellular stimulusGO:00099913800.077
cellular response to insulin stimulusGO:0032869810.075
multi organism reproductive processGO:00447032620.072
cellular response to organic cyclic compoundGO:00714072020.072
positive regulation of signalingGO:00230562700.072
response to growth factorGO:00708481890.072
response to nutrient levelsGO:00316673700.071
response to cytokineGO:00340972150.071
sensory organ developmentGO:0007423740.070
cellular response to lipidGO:00713962010.068
immune system developmentGO:0002520410.068
regulation of catalytic activityGO:00507903040.068
positive regulation of cell proliferation involved in kidney developmentGO:190172440.068
immune system processGO:00023762040.068
negative regulation of cell communicationGO:00106481580.067
positive regulation of nucleic acid templated transcriptionGO:19035081970.066
tissue developmentGO:00098882520.065
rhythmic processGO:00485111560.065
positive regulation of transcription dna templatedGO:00458931970.064
negative regulation of response to stimulusGO:00485851550.063
positive regulation of biosynthetic processGO:00098913190.061
response to ketoneGO:19016541820.061
regulation of cell differentiationGO:00455953200.060
metanephric nephron developmentGO:007221070.060
response to interleukin 1GO:0070555550.060
response to amineGO:0014075460.060
myeloid leukocyte differentiationGO:0002573200.059
regulation of intracellular signal transductionGO:19025312180.059
metanephric glomerulus developmentGO:007222430.059
regulation of immune system processGO:00026821230.059
cellular response to oxygen containing compoundGO:19017013860.059
cellular response to gonadotropin stimulusGO:0071371170.058
negative regulation of multicellular organismal processGO:00512412030.058
cellular response to campGO:0071320260.058
cellular response to interleukin 1GO:0071347370.058
glomerular mesangium developmentGO:007210940.057
negative regulation of oligodendrocyte differentiationGO:004871530.057
positive regulation of gene expressionGO:00106282440.056
positive regulation of cellular biosynthetic processGO:00313282950.055
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
response to follicle stimulating hormoneGO:0032354180.055
negative regulation of signal transductionGO:0009968830.055
positive regulation of macromolecule biosynthetic processGO:00105572470.054
cellular response to growth factor stimulusGO:00713631620.054
enzyme linked receptor protein signaling pathwayGO:00071671160.054
response to inorganic substanceGO:00100353770.054
response to light stimulusGO:0009416520.053
regulation of neuron apoptotic processGO:0043523830.052
cognitionGO:0050890920.051
regulation of myeloid cell differentiationGO:0045637120.051
cellular response to acid chemicalGO:0071229750.050
response to radiationGO:00093141370.050
negative regulation of molecular functionGO:00440921330.049
mrna 3 end processingGO:003112410.048
positive regulation of rna biosynthetic processGO:19026801970.048
regulation of erk1 and erk2 cascadeGO:0070372410.048
negative regulation of sequence specific dna binding transcription factor activityGO:0043433110.047
response to alkaloidGO:00432791320.047
response to mycophenolic acidGO:007150520.046
response to hydrogen peroxideGO:0042542890.045
cellular response to abiotic stimulusGO:0071214850.045
embryonic cranial skeleton morphogenesisGO:004870120.044
circadian rhythmGO:0007623880.044
single organism reproductive processGO:00447022970.044
regulation of neurogenesisGO:00507672470.043
multicellular organismal reproductive processGO:00486092330.043
metanephros developmentGO:0001656140.043
cellular catabolic processGO:00442482950.043
response to mechanical stimulusGO:00096121340.042
glial cell differentiationGO:0010001650.042
response to toxic substanceGO:00096361330.042
cellular ketone metabolic processGO:0042180510.042
signal transduction by phosphorylationGO:00230141440.042
regulation of glomerular mesangial cell proliferationGO:007212440.042
multicellular organism reproductionGO:00325042330.041
muscle tissue developmentGO:0060537580.041
response to isoquinoline alkaloidGO:0014072280.040
cellular response to mechanical stimulusGO:0071260480.040
positive regulation of cellular catabolic processGO:0031331710.040
negative regulation of cellular protein metabolic processGO:00322691060.039
positive regulation of molecular functionGO:00440932300.039
negative regulation of nervous system developmentGO:0051961790.039
regulation of mapk cascadeGO:00434081160.039
reproductive processGO:00224143720.039
negative regulation of developmental processGO:00510931250.038
organic substance catabolic processGO:19015753160.038
response to metal ionGO:00100382530.038
negative regulation of cell deathGO:00605482290.038
developmental growthGO:00485891000.038
regulation of catabolic processGO:00098941130.037
regulation of kidney developmentGO:0090183150.037
positive regulation of developmental processGO:00510942830.037
striated muscle tissue developmentGO:0014706580.037
positive regulation of cell differentiationGO:00455972170.037
negative regulation of signalingGO:00230571570.036
regulation of kinase activityGO:00435491170.036
eye developmentGO:0001654500.035
protein sumoylationGO:001692540.035
response to other organismGO:00517072200.035
regulation of smooth muscle cell proliferationGO:0048660750.034
positive regulation of glomerular metanephric mesangial cell proliferationGO:007230310.034
negative regulation of phosphate metabolic processGO:0045936800.034
protein dephosphorylationGO:0006470380.034
cellular response to steroid hormone stimulusGO:0071383930.033
motor neuron axon guidanceGO:000804510.033
dna metabolic processGO:0006259960.033
neuron deathGO:00709971270.032
cellular response to organonitrogen compoundGO:00714171970.032
cellular response to nitrogen compoundGO:19016992100.032
metanephric glomerulus vasculature developmentGO:007223910.032
positive regulation of cellular protein metabolic processGO:00322701670.032
leukocyte activationGO:0045321760.032
neuron differentiationGO:00301823680.032
positive regulation of phosphate metabolic processGO:00459372620.032
cardiovascular system developmentGO:00723581340.031
regulation of phosphorylationGO:00423252480.031
response to gonadotropinGO:0034698340.031
response to peptide hormoneGO:00434342780.031
negative regulation of neuron apoptotic processGO:0043524450.031
negative regulation of cell differentiationGO:0045596990.031
nucleotide metabolic processGO:00091172790.030
positive regulation of phosphorus metabolic processGO:00105622620.030
neurological system processGO:00508772190.030
nucleobase containing compound catabolic processGO:00346551520.030
cellular response to alkaloidGO:0071312250.030
cellular response to external stimulusGO:00714961180.030
cell projection organizationGO:00300303020.029
regulation of glomerulus developmentGO:009019240.028
activation of mapkkk activityGO:000018510.028
cellular macromolecule catabolic processGO:0044265290.027
hematopoietic or lymphoid organ developmentGO:0048534360.026
cellular response to peptide hormone stimulusGO:00713751200.026
purine nucleotide metabolic processGO:00061632290.026
wound healingGO:00420601220.026
chemical homeostasisGO:00488782920.026
neuron projection developmentGO:00311752730.025
cell type specific apoptotic processGO:00972851340.025
nucleobase containing small molecule metabolic processGO:00550863160.025
response to carbohydrateGO:00097431830.025
regulation of protein phosphorylationGO:00019321830.025
positive regulation of catalytic activityGO:00430851840.025
response to oxygen levelsGO:00704822650.025
glycosyl compound metabolic processGO:19016571820.025
behaviorGO:00076102050.024
positive regulation of myeloid cell differentiationGO:004563970.024
response to corticosteroidGO:00319602350.024
response to ethanolGO:00454711620.024
synaptic transmissionGO:00072682350.024
positive regulation of response to stimulusGO:00485842850.024
positive regulation of protein metabolic processGO:00512471780.024
cellular response to drugGO:0035690300.023
oligodendrocyte differentiationGO:0048709320.023
response to monosaccharideGO:00342841590.023
response to antibioticGO:0046677390.022
connective tissue developmentGO:0061448330.022
response to glucocorticoidGO:00513842230.022
response to fibroblast growth factorGO:0071774290.022
synaptic growth at neuromuscular junctionGO:005112410.022
response to cycloheximideGO:004689860.022
cell activationGO:0001775970.022
positive regulation of mesenchymal cell proliferationGO:000205340.022
response to insulinGO:00328681330.022
regulation of synaptic transmissionGO:00508041410.021
negative regulation of protein modification processGO:0031400520.021
response to reactive oxygen speciesGO:00003021200.021
regulation of bmp signaling pathwayGO:003051020.021
proteolysisGO:00065081750.021
female pregnancyGO:00075651220.021
neuron developmentGO:00486662860.021
positive regulation of phosphorylationGO:00423271770.020
nucleoside phosphate metabolic processGO:00067532830.020
positive regulation of metanephros developmentGO:007221620.020
regulation of dna metabolic processGO:0051052600.020
cellular response to peptideGO:19016531330.020
response to calcium ionGO:0051592590.020
mrna stabilizationGO:004825520.019
cellular component assemblyGO:00226073600.019
catabolic processGO:00090563510.019
regulation of cellular ketone metabolic processGO:0010565270.019
response to estradiolGO:00323551640.019
circadian behaviorGO:0048512240.019
regulation of cell developmentGO:00602842630.019
purine containing compound metabolic processGO:00725212530.019
positive regulation of cell communicationGO:00106472710.019
negative regulation of kinase activityGO:0033673270.018
intracellular transportGO:00469071850.018
rna catabolic processGO:000640130.018
interleukin 6 productionGO:0032635120.018
response to cocaineGO:0042220390.018
dephosphorylationGO:0016311980.018
negative regulation of neuron deathGO:1901215690.018
single organism biosynthetic processGO:00447113420.018
regulation of jnk cascadeGO:0046328190.018
hemopoiesisGO:0030097340.018
multi multicellular organism processGO:00447061380.018
response to external biotic stimulusGO:00432072210.018
positive regulation of mrna catabolic processGO:006101420.018
regulation of neuron deathGO:19012141150.018
regulation of myeloid leukocyte differentiationGO:0002761120.017
cellular component biogenesisGO:00440853680.017
positive regulation of cellular component organizationGO:00511302000.017
small gtpase mediated signal transductionGO:0007264360.017
ras protein signal transductionGO:0007265290.017
ribose phosphate metabolic processGO:00196932350.017
cellular cation homeostasisGO:00300031800.017
gamete generationGO:00072761240.017
cell cycleGO:00070491010.017
muscle structure developmentGO:0061061870.017
single organism carbohydrate metabolic processGO:00447231180.017
negative regulation of transferase activityGO:0051348290.017
growthGO:00400071650.017
cell cell signalingGO:00072673350.017
vesicle mediated transportGO:00161921810.017
negative regulation of cell developmentGO:0010721820.017
heterocycle catabolic processGO:00467001670.017
cell cycle phase transitionGO:0044770210.017
cellular response to hypoxiaGO:0071456510.017
organic acid metabolic processGO:00060822920.017
brain developmentGO:00074202470.016
response to testosteroneGO:0033574550.016
anatomical structure formation involved in morphogenesisGO:0048646830.016
skeletal muscle organ developmentGO:0060538330.016
regulation of peptidase activityGO:0052547550.016
nucleoside metabolic processGO:00091161790.016
regulation of nervous system developmentGO:00519602640.016
homeostatic processGO:00425923310.016
positive regulation of osteoclast differentiationGO:004567250.016
negative regulation of catalytic activityGO:00430861030.016
gastrulationGO:000736920.015
protein complex assemblyGO:00064612630.015
response to hypoxiaGO:00016662310.015
reproductionGO:00000032450.015
response to electrical stimulusGO:0051602560.015
positive regulation of immune system processGO:0002684900.015
regulation of system processGO:00440572080.015
regulation of cell proliferation involved in kidney developmentGO:190172240.015
cellular response to vascular endothelial growth factor stimulusGO:003592460.015
response to estrogenGO:00436272320.015
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154170.015
regulation of cellular amino acid metabolic processGO:000652120.015
positive regulation of hydrolase activityGO:0051345860.015
response to oxidative stressGO:00069791860.015
cellular homeostasisGO:00197252520.015
cellular response to oxygen levelsGO:0071453600.015
organelle organizationGO:00069962660.015
regulation of synaptic plasticityGO:0048167700.014
negative regulation of osteoblast differentiationGO:004566820.014
regulation of cellular component organizationGO:00511283680.014
response to ammonium ionGO:0060359710.014
negative regulation of wnt signaling pathwayGO:003017870.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
response to increased oxygen levelsGO:0036296450.014
head developmentGO:00603222470.014
single organism behaviorGO:00447081300.014
positive regulation of neurogenesisGO:00507691650.014
response to hyperoxiaGO:0055093450.014
carbohydrate derivative biosynthetic processGO:19011371240.014
microtubule organizing center organizationGO:003102310.014
positive regulation of sequence specific dna binding transcription factor activityGO:0051091240.014
developmental process involved in reproductionGO:00030061590.014
positive regulation of glomerulus developmentGO:009019340.014
positive regulation of epithelial cell proliferationGO:0050679320.014
cellular nitrogen compound catabolic processGO:00442701630.014
regulation of neuronal synaptic plasticityGO:0048168310.013
negative regulation of protein metabolic processGO:00512481140.013
sexual reproductionGO:00199531480.013
cellular amino acid metabolic processGO:00065201070.013
kidney developmentGO:0001822670.013
positive regulation of cardiac muscle contractionGO:006045240.013
heart processGO:0003015570.013
divalent inorganic cation homeostasisGO:00725071650.013
response to molecule of bacterial originGO:00022371940.013
purine ribonucleoside metabolic processGO:00461281680.013
response to norepinephrineGO:007187350.013
metal ion homeostasisGO:00550651860.013
response to corticosteroneGO:0051412400.013
cellular amine metabolic processGO:0044106380.013
regulation of cellular catabolic processGO:00313291010.013
multicellular organism growthGO:003526410.013
rhombomere morphogenesisGO:002159310.013
regulation of mrna 3 end processingGO:003144010.013
cellular metal ion homeostasisGO:00068751720.013
regulation of cellular amine metabolic processGO:003323880.013
organ regenerationGO:00311001010.013
cellular response to transforming growth factor beta stimulusGO:0071560410.013
t cell activationGO:0042110290.012
inflammatory responseGO:00069541500.012
viral transcriptionGO:001908320.012
neuron projection morphogenesisGO:00488121220.012
regulation of purine nucleotide metabolic processGO:19005421150.012
anterior posterior pattern specificationGO:000995210.012
positive regulation of glomerular mesangial cell proliferationGO:007212640.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
cellular chemical homeostasisGO:00550822470.012
muscle organ developmentGO:0007517500.012
ion homeostasisGO:00508012120.012
locomotor rhythmGO:004547510.012
neuron apoptotic processGO:0051402880.012
regulation of viral transcriptionGO:004678220.012
regulation of protein serine threonine kinase activityGO:0071900640.012
male gamete generationGO:0048232990.012
response to hexoseGO:00097461440.011
ribonucleotide metabolic processGO:00092592310.011
gtp catabolic processGO:0006184710.011
cell cycle g2 m phase transitionGO:004483960.011
sex differentiationGO:00075481130.011
circadian regulation of gene expressionGO:003292230.011
canonical wnt signaling pathwayGO:006007090.011
organic cyclic compound catabolic processGO:19013611750.011
organ morphogenesisGO:0009887750.011
purine ribonucleotide metabolic processGO:00091502270.011
muscle cell proliferationGO:0033002840.011
mitotic cell cycleGO:0000278490.011
positive regulation of protein modification processGO:00314011420.011
vasculature developmentGO:0001944700.011
regulation of embryonic developmentGO:004599520.011
cell migration involved in sprouting angiogenesisGO:000204230.011
agingGO:00075682410.011
protein complex biogenesisGO:00702712630.011
regulation of metanephric glomerulus developmentGO:007229810.011
activation of cysteine type endopeptidase activityGO:009720240.011
cellular ion homeostasisGO:00068731840.011
positive regulation of mrna metabolic processGO:190331340.011
protein modification by small protein conjugationGO:0032446310.011
centrosome organizationGO:005129710.011
regulation of mrna stabilityGO:004348830.010
chondroblast differentiationGO:006059110.010
heart morphogenesisGO:000300730.010
regulation of cell cycleGO:0051726730.010
response to woundingGO:00096112540.010
skeletal muscle tissue developmentGO:0007519310.010
regulation of hydrolase activityGO:00513361430.010
metal ion transportGO:00300012890.010
positive regulation of cellular amine metabolic processGO:003324030.010
regulation of mesenchymal cell proliferationGO:001046440.010
regulation of nucleotide metabolic processGO:00061401170.010
regulation of notch signaling pathwayGO:000859330.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
response to monoamineGO:0071867170.010

Ier2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
organ system cancerDOID:005068600.021