Rattus norvegicus

0 known processes

Top2b

topoisomerase (DNA) II beta

Top2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.243
tissue developmentGO:00098882520.241
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.232
regulation of molecular functionGO:00650093980.221
transcription dna templatedGO:00063513770.214
positive regulation of transportGO:00510502450.209
protein complex assemblyGO:00064612630.195
positive regulation of cell communicationGO:00106472710.178
signal transduction by phosphorylationGO:00230141440.176
regulation of multicellular organismal developmentGO:20000263760.173
regulation of cell proliferationGO:00421273590.157
macromolecular complex assemblyGO:00650032730.146
purine nucleoside triphosphate metabolic processGO:00091441410.144
ribonucleoside triphosphate catabolic processGO:00092031220.138
positive regulation of multicellular organismal processGO:00512403870.135
positive regulation of cell differentiationGO:00455972170.132
positive regulation of biosynthetic processGO:00098913190.131
macromolecule localizationGO:00330362520.130
nucleobase containing small molecule metabolic processGO:00550863160.123
glycosyl compound metabolic processGO:19016571820.120
regulation of cellular component organizationGO:00511283680.117
purine ribonucleotide metabolic processGO:00091502270.113
purine nucleoside triphosphate catabolic processGO:00091461220.113
regulation of cell differentiationGO:00455953200.112
protein phosphorylationGO:00064683450.105
release of cytochrome c from mitochondriaGO:000183680.104
positive regulation of phosphate metabolic processGO:00459372620.104
protein complex biogenesisGO:00702712630.101
regulation of cellular localizationGO:00603412630.101
single organism catabolic processGO:00447122830.100
positive regulation of developmental processGO:00510942830.099
regulation of nucleic acid templated transcriptionGO:19035063800.097
multicellular organism growthGO:003526410.097
rna biosynthetic processGO:00327743800.095
purine ribonucleoside triphosphate metabolic processGO:00092051400.095
cellular nitrogen compound catabolic processGO:00442701630.092
nucleic acid templated transcriptionGO:00976593790.089
regulation of catalytic activityGO:00507903040.089
carbohydrate derivative metabolic processGO:19011353460.088
cellular component biogenesisGO:00440853680.088
positive regulation of cellular component organizationGO:00511302000.087
positive regulation of response to stimulusGO:00485842850.087
positive regulation of cell developmentGO:00107201760.085
regulation of protein metabolic processGO:00512462890.084
regulation of cellular amino acid metabolic processGO:000652120.084
organophosphate catabolic processGO:00464341480.082
positive regulation of molecular functionGO:00440932300.080
glycosyl compound catabolic processGO:19016581260.080
programmed cell deathGO:00125013920.080
regulation of phosphorus metabolic processGO:00511743490.080
positive regulation of nucleobase containing compound metabolic processGO:00459353190.079
macromolecular complex subunit organizationGO:00439333390.078
cellular response to stressGO:00335542690.077
apoptotic processGO:00069153810.076
regulation of phosphorylationGO:00423252480.076
purine ribonucleoside metabolic processGO:00461281680.074
positive regulation of nitrogen compound metabolic processGO:00511733340.074
nucleoside phosphate metabolic processGO:00067532830.073
regulation of transcription from rna polymerase ii promoterGO:00063572340.073
oxoacid metabolic processGO:00434362900.072
amine metabolic processGO:0009308380.071
regulation of transcription dna templatedGO:00063553740.071
cellular component assemblyGO:00226073600.071
positive regulation of cellular biosynthetic processGO:00313282950.071
regulation of rna biosynthetic processGO:20011413810.071
synaptic transmissionGO:00072682350.070
ribose phosphate metabolic processGO:00196932350.070
nucleoside catabolic processGO:00091641260.070
cellular response to growth factor stimulusGO:00713631620.069
negative regulation of metabolic processGO:00098923310.069
head developmentGO:00603222470.068
transcription from rna polymerase ii promoterGO:00063662520.068
intracellular signal transductionGO:00355563140.068
positive regulation of programmed cell deathGO:00430681570.066
positive regulation of protein phosphorylationGO:00019341350.066
purine containing compound metabolic processGO:00725212530.066
ribonucleotide metabolic processGO:00092592310.065
positive regulation of phosphorus metabolic processGO:00105622620.065
organelle organizationGO:00069962660.064
receptor localization to synapseGO:009712020.064
rna metabolic processGO:00160704060.063
carbohydrate derivative catabolic processGO:19011361470.062
regulation of signal transductionGO:00099663180.062
purine ribonucleoside catabolic processGO:00461301240.061
nucleoside metabolic processGO:00091161790.061
ribonucleotide catabolic processGO:00092611360.060
aromatic compound catabolic processGO:00194391680.060
positive regulation of signal transductionGO:00099671750.059
response to monosaccharideGO:00342841590.059
cellular catabolic processGO:00442482950.059
cell cycle checkpointGO:000007520.059
positive regulation of rna metabolic processGO:00512542030.058
nucleoside triphosphate metabolic processGO:00091411440.058
immune system processGO:00023762040.057
heterocycle catabolic processGO:00467001670.057
positive regulation of rna biosynthetic processGO:19026801970.057
purine ribonucleotide catabolic processGO:00091541360.057
chromosome segregationGO:000705920.057
negative regulation of cellular metabolic processGO:00313242810.056
regulation of protein phosphorylationGO:00019321830.056
establishment of protein localizationGO:00451841410.056
positive regulation of gene expressionGO:00106282440.055
central nervous system developmentGO:00074173110.054
leukocyte activationGO:0045321760.054
response to decreased oxygen levelsGO:00362932370.054
negative regulation of macromolecule metabolic processGO:00106052600.054
regulation of cellular amine metabolic processGO:003323880.054
purine nucleotide metabolic processGO:00061632290.054
lens development in camera type eyeGO:0002088130.053
negative regulation of organ growthGO:004662130.053
purine nucleoside metabolic processGO:00422781690.053
protein transportGO:00150311320.053
positive regulation of signalingGO:00230562700.052
nucleotide catabolic processGO:00091661390.052
cytoskeleton organizationGO:00070101110.052
protein localizationGO:00081041910.052
negative regulation of cell cycle phase transitionGO:190198840.052
enzyme linked receptor protein signaling pathwayGO:00071671160.051
cell cycleGO:00070491010.051
regulation of intracellular signal transductionGO:19025312180.051
negative regulation of cell proliferationGO:00082851190.050
regulation of rna metabolic processGO:00512523910.050
organic acid metabolic processGO:00060822920.050
regulation of phosphate metabolic processGO:00192203490.050
positive regulation of protein metabolic processGO:00512471780.049
cellular ketone metabolic processGO:0042180510.049
cellular amine metabolic processGO:0044106380.048
growthGO:00400071650.048
organonitrogen compound catabolic processGO:19015651790.048
cellular protein localizationGO:00346131220.047
purine nucleotide catabolic processGO:00061951360.046
regulation of apoptotic processGO:00429813350.045
negative regulation of mitotic cell cycle phase transitionGO:190199130.045
response to radiationGO:00093141370.045
protein maturationGO:0051604680.045
positive regulation of transcription dna templatedGO:00458931970.045
positive regulation of macromolecule biosynthetic processGO:00105572470.044
negative regulation of nitrogen compound metabolic processGO:00511721610.044
positive regulation of catalytic activityGO:00430851840.043
intracellular transportGO:00469071850.043
nucleobase containing compound catabolic processGO:00346551520.043
protein processingGO:0016485680.042
regulation of programmed cell deathGO:00430673410.042
organophosphate metabolic processGO:00196373700.042
heart morphogenesisGO:000300730.041
positive regulation of secretionGO:00510471400.041
protein complex subunit organizationGO:00718223020.041
purine containing compound catabolic processGO:00725231380.041
response to metal ionGO:00100382530.040
positive regulation of nervous system developmentGO:00519621780.040
nucleotide metabolic processGO:00091172790.040
reproductionGO:00000032450.040
protein oligomerizationGO:00512591910.040
negative regulation of cell deathGO:00605482290.039
epithelial cell proliferationGO:0050673540.039
cellular amino acid metabolic processGO:00065201070.039
positive regulation of apoptotic processGO:00430651540.038
cell cycle processGO:0022402570.038
response to molecule of bacterial originGO:00022371940.038
regulation of cellular ketone metabolic processGO:0010565270.038
development of primary sexual characteristicsGO:00451371070.037
embryonic pattern specificationGO:000988010.037
ribonucleoside metabolic processGO:00091191740.036
behaviorGO:00076102050.036
immune responseGO:00069551040.035
regulation of hydrolase activityGO:00513361430.035
single organism organelle organizationGO:19025891800.035
developmental process involved in reproductionGO:00030061590.035
positive regulation of intracellular signal transductionGO:19025331380.035
multicellular organismal reproductive processGO:00486092330.035
neuron differentiationGO:00301823680.034
positive regulation of cellular protein metabolic processGO:00322701670.034
anatomical structure morphogenesisGO:00096532980.034
regulation of cell developmentGO:00602842630.033
nucleoside triphosphate catabolic processGO:00091431230.033
single organism reproductive processGO:00447022970.033
stress activated mapk cascadeGO:0051403350.032
regulation of nervous system developmentGO:00519602640.032
single organism intracellular transportGO:19025821660.032
positive regulation of phosphorylationGO:00423271770.032
positive regulation of retinal cell programmed cell deathGO:004667010.032
dna integrity checkpointGO:003157020.032
regulation of cellular protein metabolic processGO:00322682670.032
rhythmic processGO:00485111560.032
negative regulation of cell communicationGO:00106481580.032
organic cyclic compound catabolic processGO:19013611750.031
cell migrationGO:00164771970.031
regulation of growthGO:00400081050.031
regulation of immune system processGO:00026821230.031
protein heterooligomerizationGO:0051291890.031
ribonucleoside catabolic processGO:00424541260.031
ras protein signal transductionGO:0007265290.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.031
regulation of peptidase activityGO:0052547550.030
regulation of mapk cascadeGO:00434081160.030
epithelium developmentGO:0060429960.029
regulation of kinase activityGO:00435491170.029
regulation of cellular response to stressGO:0080135490.029
regulation of catabolic processGO:00098941130.029
positive regulation of neuron differentiationGO:00456661260.029
multi organism reproductive processGO:00447032620.029
response to oxygen levelsGO:00704822650.029
response to acid chemicalGO:00011012220.028
response to nutrient levelsGO:00316673700.028
cell projection organizationGO:00300303020.028
positive regulation of protein transportGO:0051222410.028
response to growth factorGO:00708481890.028
organelle localizationGO:0051640550.028
negative regulation of rna metabolic processGO:00512531230.027
cellular chemical homeostasisGO:00550822470.027
multicellular organism reproductionGO:00325042330.027
positive regulation of protein modification processGO:00314011420.027
cation homeostasisGO:00550801950.027
small gtpase mediated signal transductionGO:0007264360.027
regulation of anatomical structure sizeGO:00900661350.027
purine ribonucleoside triphosphate catabolic processGO:00092071220.027
nucleoside phosphate catabolic processGO:19012921400.027
inorganic cation transmembrane transportGO:00986622020.027
single organism cellular localizationGO:19025801020.026
brain developmentGO:00074202470.026
activation of protein kinase activityGO:0032147470.026
proteolysisGO:00065081750.026
reproductive processGO:00224143720.026
cellular calcium ion homeostasisGO:00068741600.026
regulation of behaviorGO:0050795610.026
gamete generationGO:00072761240.026
response to campGO:0051591910.025
regulation of cellular component movementGO:00512701500.025
cellular ion homeostasisGO:00068731840.025
homeostatic processGO:00425923310.025
circadian rhythmGO:0007623880.025
ribonucleoside triphosphate metabolic processGO:00091991410.025
reactive oxygen species biosynthetic processGO:190340980.025
purine nucleoside monophosphate catabolic processGO:0009128550.025
positive regulation of cell proliferationGO:00082842490.025
catabolic processGO:00090563510.024
cellular response to hormone stimulusGO:00328702470.024
regulation of protein transportGO:0051223680.024
ion transmembrane transportGO:00342203650.024
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.024
positive regulation of cell deathGO:00109421840.024
organic substance catabolic processGO:19015753160.024
negative regulation of transcription dna templatedGO:00458921160.024
cellular macromolecule localizationGO:00707271220.024
response to nicotineGO:0035094510.024
actin filament based processGO:0030029860.024
response to tumor necrosis factorGO:0034612560.023
regulation of cell cycleGO:0051726730.023
response to carbohydrateGO:00097431830.023
protein homooligomerizationGO:0051260910.023
negative regulation of biosynthetic processGO:00098901680.023
lipid metabolic processGO:00066292830.023
carbohydrate derivative biosynthetic processGO:19011371240.023
neurological system processGO:00508772190.023
cytosolic calcium ion homeostasisGO:00514801400.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.022
negative regulation of cellular protein metabolic processGO:00322691060.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
cellular response to endogenous stimulusGO:00714953770.022
developmental growthGO:00485891000.022
positive regulation of cell migrationGO:0030335960.022
metaphase anaphase transition of cell cycleGO:004478410.022
guanosine containing compound metabolic processGO:1901068740.021
response to hexoseGO:00097461440.021
carbohydrate metabolic processGO:00059751300.021
regulation of secretionGO:00510462240.021
regulation of feeding behaviorGO:0060259140.021
sexual reproductionGO:00199531480.021
regulation of response to stressGO:00801341260.021
mapk cascadeGO:00001651400.020
regulation of protein localizationGO:0032880810.020
divalent inorganic cation homeostasisGO:00725071650.020
metaphase anaphase transition of mitotic cell cycleGO:000709110.020
response to hypoxiaGO:00016662310.020
eye morphogenesisGO:004859240.020
cellular metal ion homeostasisGO:00068751720.020
response to ethanolGO:00454711620.020
regulation of cellular component biogenesisGO:0044087860.020
cell adhesionGO:00071551100.020
cellular response to oxygen containing compoundGO:19017013860.020
negative regulation of rna biosynthetic processGO:19026791180.020
cellular response to biotic stimulusGO:0071216590.020
regulation of neurogenesisGO:00507672470.019
circadian sleep wake cycleGO:0042745230.019
regulation of ion transmembrane transportGO:00347651210.019
regenerationGO:00310991630.019
response to inorganic substanceGO:00100353770.019
purine nucleoside catabolic processGO:00061521240.019
positive regulation of neurogenesisGO:00507691650.019
cellular response to peptide hormone stimulusGO:00713751200.019
transmission of nerve impulseGO:0019226420.019
tube developmentGO:0035295890.019
mitotic cell cycle phase transitionGO:0044772200.019
guanosine containing compound catabolic processGO:1901069710.019
regulation of membrane potentialGO:00423911100.019
response to cytokineGO:00340972150.019
agingGO:00075682410.018
neuron developmentGO:00486662860.018
gtp metabolic processGO:0046039720.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
negative regulation of protein phosphorylationGO:0001933440.018
regulation of vesicle mediated transportGO:0060627810.018
feeding behaviorGO:0007631530.018
response to peptide hormoneGO:00434342780.018
cellular component movementGO:00069282480.018
cell cell signalingGO:00072673350.018
negative regulation of developmental processGO:00510931250.018
regulation of cell cycle processGO:0010564310.018
sex differentiationGO:00075481130.018
regulation of protein modification processGO:00313991940.018
response to extracellular stimulusGO:00099913800.018
taxisGO:0042330670.017
action potentialGO:0001508540.017
negative regulation of protein metabolic processGO:00512481140.017
regulation of proteolysisGO:0030162660.017
peptidyl threonine phosphorylationGO:001810770.017
immune effector processGO:0002252530.017
regulation of neuron differentiationGO:00456642080.017
regulation of synaptic transmissionGO:00508041410.017
positive regulation of immune system processGO:0002684900.017
positive regulation of secretion by cellGO:19035321280.017
negative regulation of response to stimulusGO:00485851550.017
camera type eye developmentGO:0043010480.017
biological adhesionGO:00226101100.017
cytoskeleton dependent cytokinesisGO:006164020.017
positive regulation of cellular component biogenesisGO:0044089550.017
cellular response to peptideGO:19016531330.017
negative regulation of signalingGO:00230571570.017
negative regulation of programmed cell deathGO:00430691830.017
organonitrogen compound biosynthetic processGO:19015661670.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
cellular response to nitrogen compoundGO:19016992100.016
regulation of cytokine productionGO:0001817560.016
establishment of organelle localizationGO:0051656370.016
regulation of transmembrane transportGO:00347621220.016
anterior posterior pattern specificationGO:000995210.016
regulation of reactive oxygen species biosynthetic processGO:190342650.016
metal ion homeostasisGO:00550651860.016
neuronal action potentialGO:0019228350.016
muscle contractionGO:0006936880.016
synapse organizationGO:0050808460.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
mitotic cell cycleGO:0000278490.016
cell cycle phase transitionGO:0044770210.016
secretionGO:00469033070.016
response to nutrientGO:00075842480.016
neuron fate commitmentGO:004866340.016
regulation of transferase activityGO:00513381230.016
chromosome organizationGO:0051276360.016
peptidyl amino acid modificationGO:00181931260.016
organ morphogenesisGO:0009887750.016
regulation of ras protein signal transductionGO:0046578450.016
regulation of system processGO:00440572080.016
cation transportGO:00068123820.016
muscle cell differentiationGO:0042692520.016
neuron neuron synaptic transmissionGO:0007270600.015
rhythmic behaviorGO:0007622240.015
response to lipopolysaccharideGO:00324961910.015
negative regulation of phosphate metabolic processGO:0045936800.015
pseudopodium assemblyGO:003126930.015
response to glucoseGO:00097491360.015
positive regulation of mapk cascadeGO:0043410920.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
female sex differentiationGO:0046660590.015
negative regulation of phosphorus metabolic processGO:0010563800.015
secretion by cellGO:00329402480.015
response to transition metal nanoparticleGO:19902671220.015
regulation of establishment of protein localizationGO:0070201690.015
protein autophosphorylationGO:0046777660.015
regulation of anatomical structure morphogenesisGO:00226031410.015
response to external biotic stimulusGO:00432072210.015
gtp catabolic processGO:0006184710.015
chemical homeostasisGO:00488782920.015
ovulation cycleGO:0042698670.015
response to temperature stimulusGO:0009266940.015
regulation of protein complex assemblyGO:0043254330.015
t cell activationGO:0042110290.014
multicellular organismal signalingGO:0035637440.014
positive regulation of mitochondrion organizationGO:001082240.014
negative regulation of cell differentiationGO:0045596990.014
single organism biosynthetic processGO:00447113420.014
cell activationGO:0001775970.014
mitotic cell cycle processGO:1903047350.014
cell part morphogenesisGO:00329901230.014
positive regulation of cellular amine metabolic processGO:003324030.014
response to alkaloidGO:00432791320.014
response to woundingGO:00096112540.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
positive regulation of endocytosisGO:0045807280.014
mitotic cell cycle checkpointGO:000709310.014
centrosome organizationGO:005129710.014
negative regulation of apoptotic processGO:00430661810.014
development of primary female sexual characteristicsGO:0046545560.014
locomotionGO:00400112370.014
response to other organismGO:00517072200.014
cellular protein complex assemblyGO:0043623440.014
dna damage checkpointGO:000007720.014
spermatogenesisGO:0007283990.014
tube formationGO:003514830.014
response to retinoic acidGO:0032526630.014
cellular response to dna damage stimulusGO:0006974190.014
lymphocyte activation involved in immune responseGO:000228530.014
response to organophosphorusGO:00466831020.014
regulation of cellular catabolic processGO:00313291010.013
cell morphogenesisGO:00009021420.013
cell motilityGO:00488702020.013
g protein coupled receptor signaling pathwayGO:00071862420.013
negative regulation of epithelial cell proliferationGO:0050680160.013
cellular response to organonitrogen compoundGO:00714171970.013
reactive oxygen species metabolic processGO:0072593370.013
protein localization to nucleusGO:0034504390.013
cellular homeostasisGO:00197252520.013
activation of cysteine type endopeptidase activity involved in apoptotic processGO:000691940.013
defense responseGO:00069521940.013
apoptotic mitochondrial changesGO:0008637100.013
regulation of nucleotide metabolic processGO:00061401170.013
ion homeostasisGO:00508012120.013
atp catabolic processGO:0006200540.013
protein polymerizationGO:0051258220.013
positive regulation of cell motilityGO:2000147970.013
positive regulation of reactive oxygen species metabolic processGO:2000379160.013
endomembrane system organizationGO:0010256480.013
atp metabolic processGO:0046034720.013
regulation of cell projection organizationGO:00313441750.013
cognitionGO:0050890920.013
cellular response to lipidGO:00713962010.013
transmembrane transportGO:00550854120.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
cytokine productionGO:0001816610.013
calcium ion homeostasisGO:00550741620.013
cellular cation homeostasisGO:00300031800.013
regulation of circadian sleep wake cycleGO:0042749180.013
mitotic sister chromatid separationGO:005130610.013
positive regulation of hydrolase activityGO:0051345860.012
lymphocyte activationGO:0046649430.012
kidney developmentGO:0001822670.012
positive regulation of interleukin 1 secretionGO:005071630.012
negative regulation of catalytic activityGO:00430861030.012
positive regulation of dna metabolic processGO:0051054390.012
stem cell maintenanceGO:001982760.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
regulation of organelle organizationGO:0033043800.012
cellular macromolecular complex assemblyGO:0034622580.012
monovalent inorganic cation transportGO:00156721720.012
axis specificationGO:000979840.012
muscle structure developmentGO:0061061870.012
metal ion transportGO:00300012890.012
response to oxidative stressGO:00069791860.012
protein targetingGO:0006605610.012
negative regulation of cellular biosynthetic processGO:00313271610.012
negative regulation of molecular functionGO:00440921330.012
positive regulation of catabolic processGO:0009896780.012
cytoplasmic transportGO:00164821150.012
regulation of gtp catabolic processGO:0033124580.012
positive regulation of pseudopodium assemblyGO:003127410.012
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.012
regulation of purine nucleotide metabolic processGO:19005421150.012
regulation of endocytosisGO:0030100420.012
regulation of transporter activityGO:0032409500.012
gonad developmentGO:00084061040.012
positive regulation of cell projection organizationGO:00313461110.012
positive regulation of organelle organizationGO:0010638480.012
dna metabolic processGO:0006259960.012
anion transportGO:00068201780.011
activation of cysteine type endopeptidase activityGO:009720240.011
memoryGO:0007613540.011
sensory organ developmentGO:0007423740.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
neuron projection morphogenesisGO:00488121220.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
glycoprotein metabolic processGO:0009100240.011
male gamete generationGO:0048232990.011
neuronal ion channel clusteringGO:004516130.011
sodium ion transportGO:0006814820.011
neuron projection developmentGO:00311752730.011
regulation of metal ion transportGO:00109591180.011
negative regulation of signal transductionGO:0009968830.011
regulation of developmental growthGO:0048638450.011
cellular response to tumor necrosis factorGO:0071356460.011
vasculature developmentGO:0001944700.011
forebrain developmentGO:0030900980.011

Top2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.016
intestinal cancerDOID:1015500.016
gastrointestinal system cancerDOID:311900.016
colon cancerDOID:21900.016
colorectal cancerDOID:925600.016
large intestine cancerDOID:567200.016
colon carcinomaDOID:152000.016
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012