IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Uba2

ubiquitin-like modifier activating enzyme 2

(Aliases: Sae2,Uble1b)

RGD: 1312023
Entrez: 308508
Ensembl: ENSRNOG00000021113
UniProtKB: B1WC32

Process Predictions
Disease Predictions

Uba2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
regulation of rna metabolic process	GO:0051252	391	0.232
rna metabolic process	GO:0016070	406	0.158
regulation of transcription dna templated	GO:0006355	374	0.134
single organism reproductive process	GO:0044702	297	0.113
regulation of nucleic acid templated transcription	GO:1903506	380	0.105
transcription dna templated	GO:0006351	377	0.100
multi organism reproductive process	GO:0044703	262	0.094
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.081
nucleic acid templated transcription	GO:0097659	379	0.080
cellular component biogenesis	GO:0044085	368	0.079
rna biosynthetic process	GO:0032774	380	0.079
negative regulation of rna metabolic process	GO:0051253	123	0.079
regulation of rna biosynthetic process	GO:2001141	381	0.075
cellular response to endogenous stimulus	GO:0071495	377	0.068
regulation of multicellular organismal development	GO:2000026	376	0.068
negative regulation of metabolic process	GO:0009892	331	0.065
negative regulation of rna splicing	GO:0033119	3	0.064
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.064
reproductive process	GO:0022414	372	0.063
transcription from rna polymerase ii promoter	GO:0006366	252	0.060
negative regulation of cellular metabolic process	GO:0031324	281	0.060
positive regulation of rna metabolic process	GO:0051254	203	0.056
organelle organization	GO:0006996	266	0.052
cellular component assembly	GO:0022607	360	0.051
multicellular organism reproduction	GO:0032504	233	0.051
transforming growth factor beta3 production	GO:0032907	2	0.048
reproduction	GO:0000003	245	0.048
regulation of mrna splicing via spliceosome	GO:0048024	3	0.046
lipid metabolic process	GO:0006629	283	0.044
positive regulation of biosynthetic process	GO:0009891	319	0.042
response to extracellular stimulus	GO:0009991	380	0.041
negative regulation of transcription dna templated	GO:0045892	116	0.040
protein complex assembly	GO:0006461	263	0.038
positive regulation of transcription dna templated	GO:0045893	197	0.035
regulation of signal transduction	GO:0009966	318	0.034
positive regulation of gene expression	GO:0010628	244	0.034
negative regulation of gene expression	GO:0010629	199	0.033
regulation of cell development	GO:0060284	263	0.031
negative regulation of developmental process	GO:0051093	125	0.031
response to nutrient levels	GO:0031667	370	0.031
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.031
protein complex subunit organization	GO:0071822	302	0.031
embryonic pattern specification	GO:0009880	1	0.031
cellular response to hormone stimulus	GO:0032870	247	0.030
negative regulation of biosynthetic process	GO:0009890	168	0.030
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.029
regulation of cell proliferation	GO:0042127	359	0.029
sexual reproduction	GO:0019953	148	0.029
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.028
positive regulation of rna biosynthetic process	GO:1902680	197	0.028
response to peptide hormone	GO:0043434	278	0.028
spindle organization	GO:0007051	2	0.028
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.027
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.026
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.026
regulation of cell differentiation	GO:0045595	320	0.024
axis specification	GO:0009798	4	0.024
regulation of alternative mrna splicing via spliceosome	GO:0000381	2	0.024
regulation of stem cell differentiation	GO:2000736	2	0.023
negative regulation of macromolecule metabolic process	GO:0010605	260	0.023
negative regulation of rna biosynthetic process	GO:1902679	118	0.023
single organism biosynthetic process	GO:0044711	342	0.023
response to peptide	GO:1901652	292	0.022
neurological system process	GO:0050877	219	0.022
positive regulation of response to stimulus	GO:0048584	285	0.022
intracellular transport	GO:0046907	185	0.022
negative regulation of mrna splicing via spliceosome	GO:0048025	2	0.022
protein oligomerization	GO:0051259	191	0.021
mitotic spindle organization	GO:0007052	2	0.021
positive regulation of cellular biosynthetic process	GO:0031328	295	0.021
protein complex biogenesis	GO:0070271	263	0.021
tissue development	GO:0009888	252	0.021
macromolecular complex assembly	GO:0065003	273	0.020
regulation of programmed cell death	GO:0043067	341	0.019
programmed cell death	GO:0012501	392	0.019
cellular lipid metabolic process	GO:0044255	208	0.019
negative regulation of cell proliferation	GO:0008285	119	0.019
positive regulation of cell death	GO:0010942	184	0.019
positive regulation of signaling	GO:0023056	270	0.018
multicellular organismal reproductive process	GO:0048609	233	0.018
developmental process involved in reproduction	GO:0003006	159	0.018
amine metabolic process	GO:0009308	38	0.018
cellular macromolecular complex assembly	GO:0034622	58	0.017
negative regulation of cell differentiation	GO:0045596	99	0.017
bmp signaling pathway	GO:0030509	4	0.017
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.016
regulation of cellular localization	GO:0060341	263	0.016
gamete generation	GO:0007276	124	0.016
organic acid metabolic process	GO:0006082	292	0.016
alternative mrna splicing via spliceosome	GO:0000380	4	0.016
response to growth factor	GO:0070848	189	0.016
multi multicellular organism process	GO:0044706	138	0.016
anterior posterior pattern specification	GO:0009952	1	0.016
regulation of apoptotic process	GO:0042981	335	0.015
positive regulation of transforming growth factor beta3 production	GO:0032916	2	0.015
reproductive system development	GO:0061458	128	0.015
regulation of molecular function	GO:0065009	398	0.015
positive regulation of programmed cell death	GO:0043068	157	0.015
positive regulation of multicellular organismal process	GO:0051240	387	0.015
positive regulation of cell communication	GO:0010647	271	0.015
olfactory behavior	GO:0042048	2	0.015
nucleosome organization	GO:0034728	1	0.015
negative regulation of multicellular organismal process	GO:0051241	203	0.014
macromolecular complex subunit organization	GO:0043933	339	0.014
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.014
embryonic axis specification	GO:0000578	1	0.014
lipid biosynthetic process	GO:0008610	128	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.014
monocarboxylic acid metabolic process	GO:0032787	152	0.014
neuron development	GO:0048666	286	0.014
cellular response to growth factor stimulus	GO:0071363	162	0.014
nitrogen compound transport	GO:0071705	229	0.014
homeostatic process	GO:0042592	331	0.014
chromatin assembly or disassembly	GO:0006333	1	0.013
oxoacid metabolic process	GO:0043436	290	0.013
rna splicing	GO:0008380	11	0.013
response to oxygen levels	GO:0070482	265	0.013
negative regulation of cellular biosynthetic process	GO:0031327	161	0.013
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO:0097296	1	0.013
urogenital system development	GO:0001655	78	0.013
cellular amine metabolic process	GO:0044106	38	0.013
carbohydrate metabolic process	GO:0005975	130	0.013
embryo development	GO:0009790	49	0.013
cellular response to oxygen containing compound	GO:1901701	386	0.013
response to estrogen	GO:0043627	232	0.013
sex differentiation	GO:0007548	113	0.013
positive regulation of apoptotic process	GO:0043065	154	0.013
dendrite development	GO:0016358	72	0.013
regulation of protein metabolic process	GO:0051246	289	0.012
mrna stabilization	GO:0048255	2	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
regulation of neurogenesis	GO:0050767	247	0.012
protein sumoylation	GO:0016925	4	0.012
macromolecule localization	GO:0033036	252	0.012
chemosensory behavior	GO:0007635	2	0.012
regulation of epithelial cell proliferation	GO:0050678	49	0.011
positive regulation of neuron differentiation	GO:0045666	126	0.011
single organism carbohydrate metabolic process	GO:0044723	118	0.011
chromosome segregation	GO:0007059	2	0.011
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
microtubule cytoskeleton organization	GO:0000226	25	0.011
cellular homeostasis	GO:0019725	252	0.011
male mating behavior	GO:0060179	3	0.011
positive regulation of protein metabolic process	GO:0051247	178	0.011
regulation of cellular component organization	GO:0051128	368	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
chemical homeostasis	GO:0048878	292	0.011
positive regulation of cell differentiation	GO:0045597	217	0.010
behavior	GO:0007610	205	0.010
cell cycle process	GO:0022402	57	0.010
male gamete generation	GO:0048232	99	0.010
plasminogen activation	GO:0031639	2	0.010
positive regulation of cell development	GO:0010720	176	0.010
apoptotic process	GO:0006915	381	0.010
neuron projection development	GO:0031175	273	0.010

Uba2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.013
disease of anatomical entity	DOID:7	0.013
disease of metabolism	DOID:0014667	0.011

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