Rattus norvegicus

0 known processes

Sppl2a

signal peptide peptidase-like 2A

(Aliases: RGD1563001)

Sppl2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123820.125
brain developmentGO:00074202470.109
anatomical structure morphogenesisGO:00096532980.097
homeostatic processGO:00425923310.094
transcription dna templatedGO:00063513770.093
immune system processGO:00023762040.087
Human
anion transportGO:00068201780.086
regulation of nucleic acid templated transcriptionGO:19035063800.085
head developmentGO:00603222470.079
transmembrane transportGO:00550854120.078
regulation of cell proliferationGO:00421273590.070
carbohydrate derivative metabolic processGO:19011353460.069
single organism reproductive processGO:00447022970.067
neuron developmentGO:00486662860.066
metal ion homeostasisGO:00550651860.065
ion homeostasisGO:00508012120.064
cellular ion homeostasisGO:00068731840.061
rna biosynthetic processGO:00327743800.061
regulation of apoptotic processGO:00429813350.060
organelle organizationGO:00069962660.060
cation homeostasisGO:00550801950.058
cellular response to hormone stimulusGO:00328702470.058
cellular amino acid metabolic processGO:00065201070.057
rna metabolic processGO:00160704060.056
regulation of molecular functionGO:00650093980.055
regulation of rna biosynthetic processGO:20011413810.054
reproductive system developmentGO:00614581280.053
oxoacid metabolic processGO:00434362900.053
cellular cation homeostasisGO:00300031800.052
central nervous system developmentGO:00074173110.052
neuron differentiationGO:00301823680.052
regulation of transcription dna templatedGO:00063553740.051
regulation of system processGO:00440572080.050
metal ion transportGO:00300012890.050
cellular homeostasisGO:00197252520.049
regulation of cellular amino acid metabolic processGO:000652120.048
regulation of kinase activityGO:00435491170.046
ion transmembrane transportGO:00342203650.045
amine metabolic processGO:0009308380.045
regulation of cell differentiationGO:00455953200.045
cellular component biogenesisGO:00440853680.045
protein phosphorylationGO:00064683450.044
macromolecular complex subunit organizationGO:00439333390.044
cellular amine metabolic processGO:0044106380.043
cell projection organizationGO:00300303020.042
ribonucleoside triphosphate catabolic processGO:00092031220.041
cellular ketone metabolic processGO:0042180510.040
regulation of rna metabolic processGO:00512523910.040
regulation of cellular component organizationGO:00511283680.038
regulation of multicellular organismal developmentGO:20000263760.038
positive regulation of response to stimulusGO:00485842850.038
agingGO:00075682410.037
regulation of phosphorylationGO:00423252480.037
cell part morphogenesisGO:00329901230.037
organic substance catabolic processGO:19015753160.037
protein localizationGO:00081041910.037
tissue developmentGO:00098882520.036
single organism organelle organizationGO:19025891800.036
positive regulation of nucleobase containing compound metabolic processGO:00459353190.036
carbohydrate metabolic processGO:00059751300.035
positive regulation of molecular functionGO:00440932300.035
regulation of transferase activityGO:00513381230.034
regulation of cellular amine metabolic processGO:003323880.034
regulation of synaptic growth at neuromuscular junctionGO:000858210.034
response to ketoneGO:19016541820.034
regulation of nervous system developmentGO:00519602640.034
actin cytoskeleton organizationGO:0030036730.034
positive regulation of biosynthetic processGO:00098913190.034
single organism catabolic processGO:00447122830.034
regulation of cellular ketone metabolic processGO:0010565270.033
positive regulation of developmental processGO:00510942830.033
reproductionGO:00000032450.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
reproductive processGO:00224143720.033
response to peptideGO:19016522920.033
cellular metal ion homeostasisGO:00068751720.032
positive regulation of cell proliferationGO:00082842490.032
chemical homeostasisGO:00488782920.032
positive regulation of phosphorylationGO:00423271770.031
response to woundingGO:00096112540.031
nucleobase containing small molecule metabolic processGO:00550863160.031
cellular chemical homeostasisGO:00550822470.030
positive regulation of protein metabolic processGO:00512471780.030
signal transduction by phosphorylationGO:00230141440.030
nucleic acid templated transcriptionGO:00976593790.030
epithelium developmentGO:0060429960.030
positive regulation of cellular amino acid metabolic processGO:004576410.029
response to mechanical stimulusGO:00096121340.029
divalent inorganic cation homeostasisGO:00725071650.029
nucleotide metabolic processGO:00091172790.029
regulation of intracellular signal transductionGO:19025312180.029
inorganic ion transmembrane transportGO:00986602290.028
membrane organizationGO:0061024940.028
neuron projection developmentGO:00311752730.028
positive regulation of cell communicationGO:00106472710.028
apoptotic processGO:00069153810.028
synaptic transmissionGO:00072682350.028
negative regulation of cell communicationGO:00106481580.028
g protein coupled receptor signaling pathwayGO:00071862420.028
nucleoside triphosphate catabolic processGO:00091431230.027
cellular response to insulin stimulusGO:0032869810.027
mesoderm developmentGO:000749820.027
cellular response to endogenous stimulusGO:00714953770.027
response to radiationGO:00093141370.027
nucleoside phosphate metabolic processGO:00067532830.027
single organism carbohydrate metabolic processGO:00447231180.026
carbohydrate derivative biosynthetic processGO:19011371240.026
regulation of signal transductionGO:00099663180.026
positive regulation of phosphorus metabolic processGO:00105622620.026
secretionGO:00469033070.026
cell type specific apoptotic processGO:00972851340.026
response to insulinGO:00328681330.026
circulatory system processGO:00030131830.025
positive regulation of cellular amine metabolic processGO:003324030.025
negative regulation of signalingGO:00230571570.025
purine containing compound metabolic processGO:00725212530.025
positive regulation of cellular component organizationGO:00511302000.025
positive regulation of transferase activityGO:0051347810.025
cellular response to oxygen containing compoundGO:19017013860.025
heterocycle catabolic processGO:00467001670.025
cellular response to stressGO:00335542690.024
regulation of ion transportGO:00432692450.024
regulation of protein metabolic processGO:00512462890.024
positive regulation of multicellular organismal processGO:00512403870.024
cytosolic calcium ion homeostasisGO:00514801400.024
actin filament based processGO:0030029860.024
positive regulation of cellular biosynthetic processGO:00313282950.024
calcium ion homeostasisGO:00550741620.024
cell projection morphogenesisGO:00488581230.024
single organism biosynthetic processGO:00447113420.024
regulation of ion transmembrane transportGO:00347651210.024
reproductive structure developmentGO:00486081280.024
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
motor neuron axon guidanceGO:000804510.023
purine ribonucleoside metabolic processGO:00461281680.023
secretion by cellGO:00329402480.023
regulation of protein modification processGO:00313991940.023
carbohydrate derivative catabolic processGO:19011361470.022
organic acid metabolic processGO:00060822920.022
growthGO:00400071650.022
positive regulation of phosphate metabolic processGO:00459372620.022
organophosphate metabolic processGO:00196373700.022
cellular catabolic processGO:00442482950.022
response to corticosteroidGO:00319602350.022
response to extracellular stimulusGO:00099913800.022
positive regulation of signal transductionGO:00099671750.022
positive regulation of signalingGO:00230562700.022
regulation of metal ion transportGO:00109591180.021
sexual reproductionGO:00199531480.021
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.021
ras protein signal transductionGO:0007265290.021
vesicle mediated transportGO:00161921810.021
developmental process involved in reproductionGO:00030061590.021
blood circulationGO:00080151830.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
proteolysisGO:00065081750.021
Human
cellular response to organic cyclic compoundGO:00714072020.020
neurological system processGO:00508772190.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
response to inorganic substanceGO:00100353770.020
cardiovascular system developmentGO:00723581340.020
neuron projection morphogenesisGO:00488121220.020
cellular component movementGO:00069282480.020
regulation of protein kinase activityGO:00458591050.020
regulation of cell developmentGO:00602842630.020
regulation of organelle organizationGO:0033043800.020
establishment of protein localizationGO:00451841410.020
cation transmembrane transportGO:00986552630.020
regulation of neuron deathGO:19012141150.020
cellular response to peptideGO:19016531330.020
ribose phosphate metabolic processGO:00196932350.019
protein localization to organelleGO:0033365570.019
purine ribonucleotide catabolic processGO:00091541360.019
positive regulation of catalytic activityGO:00430851840.019
tube developmentGO:0035295890.019
transcription from rna polymerase ii promoterGO:00063662520.019
purine nucleotide catabolic processGO:00061951360.019
sensory organ developmentGO:0007423740.019
alternative mrna splicing via spliceosomeGO:000038040.019
response to nutrient levelsGO:00316673700.019
cell motilityGO:00488702020.019
regulation of neuron differentiationGO:00456642080.019
regulation of alternative mrna splicing via spliceosomeGO:000038120.019
developmental growthGO:00485891000.018
regulation of cell projection organizationGO:00313441750.018
intracellular transportGO:00469071850.018
cellular component morphogenesisGO:00329891550.018
nucleoside monophosphate metabolic processGO:0009123930.018
aromatic compound catabolic processGO:00194391680.018
anatomical structure formation involved in morphogenesisGO:0048646830.018
immune system developmentGO:0002520410.018
purine ribonucleoside catabolic processGO:00461301240.018
macromolecule localizationGO:00330362520.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
regulation of protein phosphorylationGO:00019321830.017
regulation of cellular protein metabolic processGO:00322682670.017
response to metal ionGO:00100382530.017
localization of cellGO:00516742020.017
inorganic cation transmembrane transportGO:00986622020.017
negative regulation of cellular metabolic processGO:00313242810.017
regulation of fat cell differentiationGO:004559830.017
rhythmic processGO:00485111560.017
erythrocyte differentiationGO:003021810.017
positive regulation of rna metabolic processGO:00512542030.017
regulation of phosphorus metabolic processGO:00511743490.017
regulation of transmembrane transportGO:00347621220.017
regulation of mapk cascadeGO:00434081160.017
action potentialGO:0001508540.017
peptidyl amino acid modificationGO:00181931260.017
programmed cell deathGO:00125013920.017
myeloid cell differentiationGO:0030099220.017
response to peptide hormoneGO:00434342780.017
cellular component assemblyGO:00226073600.016
intracellular protein transportGO:0006886790.016
locomotionGO:00400112370.016
circulatory system developmentGO:00723591340.016
positive regulation of gene expressionGO:00106282440.016
purine nucleotide metabolic processGO:00061632290.016
cilium morphogenesisGO:006027120.016
intracellular signal transductionGO:00355563140.016
regulation of immune system processGO:00026821230.016
Human
muscle structure developmentGO:0061061870.016
positive regulation of cell deathGO:00109421840.016
response to light stimulusGO:0009416520.016
negative regulation of metabolic processGO:00098923310.016
carboxylic acid metabolic processGO:00197522890.016
organelle inheritanceGO:004830820.016
positive regulation of cellular protein metabolic processGO:00322701670.016
lipid metabolic processGO:00066292830.016
axis specificationGO:000979840.016
negative regulation of transcription dna templatedGO:00458921160.016
response to ethanolGO:00454711620.015
embryo developmentGO:0009790490.015
response to transition metal nanoparticleGO:19902671220.015
multicellular organism reproductionGO:00325042330.015
single organism intracellular transportGO:19025821660.015
anion transmembrane transportGO:0098656770.015
heart morphogenesisGO:000300730.015
multi organism reproductive processGO:00447032620.015
neuron deathGO:00709971270.015
nitrogen compound transportGO:00717052290.015
erythrocyte homeostasisGO:003410120.015
cilium assemblyGO:004238420.015
negative regulation of programmed cell deathGO:00430691830.015
response to decreased oxygen levelsGO:00362932370.015
regulation of blood circulationGO:19035221100.015
organic cyclic compound catabolic processGO:19013611750.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
positive regulation of cell differentiationGO:00455972170.015
response to molecule of bacterial originGO:00022371940.015
heart processGO:0003015570.015
multicellular organismal reproductive processGO:00486092330.015
regulation of neurogenesisGO:00507672470.015
protein transportGO:00150311320.015
regulation of growthGO:00400081050.014
positive regulation of protein modification processGO:00314011420.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
negative regulation of molecular functionGO:00440921330.014
cellular response to peptide hormone stimulusGO:00713751200.014
gland developmentGO:00487321550.014
positive regulation of nervous system developmentGO:00519621780.014
positive regulation of programmed cell deathGO:00430681570.014
monosaccharide metabolic processGO:0005996610.014
cell cell signalingGO:00072673350.014
positive regulation of rna biosynthetic processGO:19026801970.014
neuronal action potentialGO:0019228350.014
cellular calcium ion homeostasisGO:00068741600.014
response to vitaminGO:00332731310.014
cellular macromolecule localizationGO:00707271220.014
response to nutrientGO:00075842480.014
cellular response to growth factor stimulusGO:00713631620.014
retina development in camera type eyeGO:0060041270.014
salivary gland morphogenesisGO:000743510.014
embryonic placenta developmentGO:000189210.014
cellular response to nitrogen compoundGO:19016992100.014
negative regulation of gene expressionGO:00106291990.014
organonitrogen compound catabolic processGO:19015651790.014
single organism cellular localizationGO:19025801020.014
regulation of catalytic activityGO:00507903040.014
neural crest cell differentiationGO:001403320.013
regulation of canonical wnt signaling pathwayGO:006082840.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
response to other organismGO:00517072200.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
cellular nitrogen compound catabolic processGO:00442701630.013
regulation of synaptic transmissionGO:00508041410.013
axonogenesisGO:0007409710.013
cell fate determinationGO:000170920.013
regulation of programmed cell deathGO:00430673410.013
positive regulation of intracellular signal transductionGO:19025331380.013
glycosyl compound metabolic processGO:19016571820.013
protein complex subunit organizationGO:00718223020.013
nucleobase containing compound catabolic processGO:00346551520.013
multicellular organismal signalingGO:0035637440.013
hemopoiesisGO:0030097340.013
regulation of locomotionGO:00400121480.013
positive regulation of transportGO:00510502450.013
regulation of protein localizationGO:0032880810.013
negative regulation of response to stimulusGO:00485851550.013
catabolic processGO:00090563510.013
nucleoside metabolic processGO:00091161790.013
response to hypoxiaGO:00016662310.013
negative regulation of signal transductionGO:0009968830.013
embryonic pattern specificationGO:000988010.013
cellular response to organonitrogen compoundGO:00714171970.012
gamete generationGO:00072761240.012
regulation of homeostatic processGO:00328441010.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
salivary gland developmentGO:000743130.012
cellular response to abiotic stimulusGO:0071214850.012
organic acid transportGO:00158491160.012
nucleoside phosphate biosynthetic processGO:19012931020.012
actin filament organizationGO:0007015420.012
positive regulation of transcription dna templatedGO:00458931970.012
negative regulation of developmental processGO:00510931250.012
protein targetingGO:0006605610.012
muscle contractionGO:0006936880.012
camera type eye morphogenesisGO:004859320.012
regulation of membrane potentialGO:00423911100.012
purine ribonucleotide metabolic processGO:00091502270.012
protein complex assemblyGO:00064612630.012
positive regulation of protein phosphorylationGO:00019341350.012
purine nucleoside catabolic processGO:00061521240.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
mapk cascadeGO:00001651400.012
cytoplasmic transportGO:00164821150.012
regulation of cell cycleGO:0051726730.012
development of primary sexual characteristicsGO:00451371070.012
positive regulation of cell projection organizationGO:00313461110.012
vasculature developmentGO:0001944700.012
response to estrogenGO:00436272320.012
response to bacteriumGO:00096172000.012
lipid biosynthetic processGO:00086101280.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
regulation of protein serine threonine kinase activityGO:0071900640.012
cell migrationGO:00164771970.012
sex differentiationGO:00075481130.011
negative regulation of organ growthGO:004662130.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
nucleotide catabolic processGO:00091661390.011
macromolecule catabolic processGO:0009057580.011
response to lipopolysaccharideGO:00324961910.011
organophosphate catabolic processGO:00464341480.011
peptidyl tyrosine modificationGO:0018212720.011
negative regulation of growthGO:0045926370.011
reactive oxygen species metabolic processGO:0072593370.011
neuromuscular processGO:005090520.011
purine ribonucleotide biosynthetic processGO:0009152810.011
mitochondrion organizationGO:0007005350.011
gonad developmentGO:00084061040.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
camera type eye developmentGO:0043010480.011
cell morphogenesis involved in differentiationGO:00009041190.011
cell morphogenesisGO:00009021420.011
regulation of phosphate metabolic processGO:00192203490.011
potassium ion transportGO:0006813970.011
regulation of mrna splicing via spliceosomeGO:004802430.011
forebrain developmentGO:0030900980.011
protein complex biogenesisGO:00702712630.011
cilium organizationGO:004478220.011
negative regulation of macromolecule metabolic processGO:00106052600.011
purine nucleoside metabolic processGO:00422781690.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
organic hydroxy compound metabolic processGO:19016151150.011
ribonucleoside metabolic processGO:00091191740.010
negative regulation of apoptotic processGO:00430661810.010
negative regulation of cellular biosynthetic processGO:00313271610.010
multicellular organism growthGO:003526410.010
response to calcium ionGO:0051592590.010
negative regulation of protein metabolic processGO:00512481140.010
regulation of anatomical structure sizeGO:00900661350.010
hormone transportGO:00099141210.010
monovalent inorganic cation transportGO:00156721720.010
cortical actin cytoskeleton organizationGO:003086620.010
cellular response to alcoholGO:0097306870.010
negative regulation of cell deathGO:00605482290.010

Sppl2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.017
disease of cellular proliferationDOID:1456600.011
inherited metabolic disorderDOID:65500.011
nervous system diseaseDOID:86300.011
disease of anatomical entityDOID:700.011