Rattus norvegicus

0 known processes

A1i3

alpha-1-inhibitor III

A1i3 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
naphthalene containing compound metabolic processGO:009042020.663
response to peptide hormoneGO:00434342780.636
response to extracellular stimulusGO:00099913800.602
response to cesium ionGO:001016420.565
cellular response to lipidGO:00713962010.432
nicotine metabolic processGO:001893310.419
response to purine containing compoundGO:00140741260.391
alkaloid metabolic processGO:000982030.357
epoxygenase p450 pathwayGO:001937310.325
carbohydrate derivative metabolic processGO:19011353460.319
organic substance catabolic processGO:19015753160.303
response to nutrient levelsGO:00316673700.302
aromatic compound catabolic processGO:00194391680.298
unsaturated fatty acid metabolic processGO:0033559390.298
cellular catabolic processGO:00442482950.266
icosanoid metabolic processGO:0006690380.254
naphthalene metabolic processGO:001893120.249
halogenated hydrocarbon metabolic processGO:004219740.237
fatty acid derivative metabolic processGO:1901568380.232
chlorinated hydrocarbon metabolic processGO:004219640.219
lipid metabolic processGO:00066292830.215
estrogen biosynthetic processGO:000670360.211
negative regulation of serine type peptidase activityGO:190257210.207
purine nucleoside metabolic processGO:00422781690.203
response to peptideGO:19016522920.201
organophosphate metabolic processGO:00196373700.196
response to sulfur dioxideGO:001047730.191
long chain fatty acid metabolic processGO:0001676320.189
response to xenobiotic stimulusGO:0009410230.189
response to campGO:0051591910.184
organic acid metabolic processGO:00060822920.182
purine containing compound metabolic processGO:00725212530.177
cellular response to hormone stimulusGO:00328702470.171
nucleotide metabolic processGO:00091172790.170
response to metal ionGO:00100382530.167
regulation of vasculature developmentGO:1901342440.166
response to nutrientGO:00075842480.164
monocarboxylic acid metabolic processGO:00327871520.163
organic cyclic compound catabolic processGO:19013611750.158
xenobiotic metabolic processGO:0006805190.157
phenylpropanoid metabolic processGO:000969850.156
response to acid chemicalGO:00011012220.154
purine ribonucleoside metabolic processGO:00461281680.149
ribonucleotide metabolic processGO:00092592310.149
nucleoside phosphate metabolic processGO:00067532830.142
response to vitaminGO:00332731310.139
cellular amino acid metabolic processGO:00065201070.137
heterocycle catabolic processGO:00467001670.136
single organism catabolic processGO:00447122830.134
nucleobase containing small molecule metabolic processGO:00550863160.134
cellular lipid metabolic processGO:00442552080.130
ribonucleoside metabolic processGO:00091191740.128
cellular sodium ion homeostasisGO:000688340.125
oxoacid metabolic processGO:00434362900.121
fatty acid metabolic processGO:0006631990.121
transmission of nerve impulseGO:0019226420.120
negative regulation of serine type endopeptidase activityGO:190000410.118
regulation of hydrolase activityGO:00513361430.117
blood circulationGO:00080151830.115
multi multicellular organism processGO:00447061380.114
triglyceride metabolic processGO:0006641210.110
cellular response to steroid hormone stimulusGO:0071383930.109
cellular response to xenobiotic stimulusGO:0071466190.104
organophosphate catabolic processGO:00464341480.103
organonitrogen compound biosynthetic processGO:19015661670.103
response to lipopolysaccharideGO:00324961910.103
cellular response to interleukin 6GO:007135490.102
response to herbicideGO:0009635160.098
cofactor metabolic processGO:0051186950.097
regulation of programmed cell deathGO:00430673410.093
coumarin metabolic processGO:000980450.093
glycerolipid metabolic processGO:0046486670.092
amine metabolic processGO:0009308380.091
pyridine containing compound metabolic processGO:0072524320.090
ribose phosphate metabolic processGO:00196932350.088
steroid metabolic processGO:0008202730.087
angiotensin mediated drinking behaviorGO:000305120.087
insecticide metabolic processGO:001714340.085
glycosyl compound metabolic processGO:19016571820.085
regulation of serine type peptidase activityGO:190257110.084
trichloroethylene metabolic processGO:001897910.083
negative regulation of peptidase activityGO:0010466380.083
lipid localizationGO:0010876620.083
response to calcium ionGO:0051592590.083
nucleoside triphosphate metabolic processGO:00091411440.082
response to chromateGO:004668730.082
purine nucleotide catabolic processGO:00061951360.080
behaviorGO:00076102050.080
regulation of purine nucleotide catabolic processGO:0033121650.079
response to insulinGO:00328681330.078
response to corticosteroidGO:00319602350.077
vasculature developmentGO:0001944700.075
organic acid biosynthetic processGO:0016053830.075
response to triglycerideGO:003401430.075
response to oxygen levelsGO:00704822650.073
purine nucleotide metabolic processGO:00061632290.073
response to lead ionGO:0010288330.073
positive regulation of nitrogen compound metabolic processGO:00511733340.073
liver developmentGO:0001889900.072
angiogenesisGO:0001525530.072
norepinephrine secretionGO:0048243160.071
response to other organismGO:00517072200.071
single organism biosynthetic processGO:00447113420.071
multi organism reproductive processGO:00447032620.068
organ regenerationGO:00311001010.067
anion transportGO:00068201780.067
response to decreased oxygen levelsGO:00362932370.067
cellular nitrogen compound catabolic processGO:00442701630.066
purine ribonucleotide catabolic processGO:00091541360.065
arachidonic acid metabolic processGO:0019369200.065
response to molecule of bacterial originGO:00022371940.064
response to hypoxiaGO:00016662310.063
nucleoside triphosphate catabolic processGO:00091431230.063
homeostatic processGO:00425923310.062
response to glucocorticoidGO:00513842230.062
oxidation reduction processGO:00551143040.061
drug metabolic processGO:0017144110.061
androgen biosynthetic processGO:0006702100.060
coenzyme metabolic processGO:0006732860.060
catechol containing compound biosynthetic processGO:000971390.059
positive regulation of nucleobase containing compound metabolic processGO:00459353190.059
agingGO:00075682410.059
neutral lipid metabolic processGO:0006638210.058
ribonucleoside catabolic processGO:00424541260.058
lipid biosynthetic processGO:00086101280.058
catabolic processGO:00090563510.057
macromolecule localizationGO:00330362520.057
phenol containing compound metabolic processGO:0018958300.056
response to bacteriumGO:00096172000.056
purine ribonucleoside triphosphate catabolic processGO:00092071220.055
response to organophosphorusGO:00466831020.055
response to external biotic stimulusGO:00432072210.055
female pregnancyGO:00075651220.053
purine nucleotide biosynthetic processGO:0006164830.053
regulation of angiogenesisGO:0045765390.052
hepaticobiliary system developmentGO:0061008900.052
ion homeostasisGO:00508012120.052
response to transition metal nanoparticleGO:19902671220.051
negative regulation of cellular metabolic processGO:00313242810.051
lipid transportGO:0006869610.050
purine ribonucleotide metabolic processGO:00091502270.050
positive regulation of homeostatic processGO:0032846490.049
positive regulation of extracellular matrix organizationGO:190305540.049
nucleoside phosphate catabolic processGO:19012921400.049
cellular hormone metabolic processGO:0034754490.048
organophosphate biosynthetic processGO:00904071430.048
benzene containing compound metabolic processGO:0042537220.048
carbohydrate derivative catabolic processGO:19011361470.048
cell cell signalingGO:00072673350.047
cellular ketone metabolic processGO:0042180510.047
regulation of molecular functionGO:00650093980.046
organonitrogen compound catabolic processGO:19015651790.046
reproductive processGO:00224143720.046
response to vitamin b6GO:003451610.045
negative regulation of endopeptidase activityGO:0010951360.044
response to biotic stimulusGO:00096072260.044
response to ketoneGO:19016541820.044
catenin import into nucleusGO:003541110.044
fibrinolysisGO:004273020.044
purine nucleoside catabolic processGO:00061521240.043
c21 steroid hormone biosynthetic processGO:0006700100.042
androgen metabolic processGO:0008209140.042
circulatory system developmentGO:00723591340.042
cell projection organizationGO:00300303020.042
carboxylic acid metabolic processGO:00197522890.042
nucleobase containing compound catabolic processGO:00346551520.041
secondary metabolic processGO:0019748150.040
regulation of apoptotic processGO:00429813350.040
cellular response to gonadotropin stimulusGO:0071371170.040
negative regulation of cellular protein metabolic processGO:00322691060.040
adrenal gland developmentGO:0030325110.039
cellular response to peptide hormone stimulusGO:00713751200.039
renin angiotensin regulation of aldosterone productionGO:000201830.039
regulation of purine nucleotide metabolic processGO:19005421150.039
nucleoside catabolic processGO:00091641260.038
programmed cell deathGO:00125013920.038
lipid catabolic processGO:0016042460.037
negative regulation of metabolic processGO:00098923310.037
regulation of neuron projection developmentGO:00109751610.036
sulfur compound metabolic processGO:0006790700.036
purine ribonucleoside catabolic processGO:00461301240.036
regulation of neuronal synaptic plasticityGO:0048168310.036
positive regulation of multicellular organismal processGO:00512403870.035
nucleoside metabolic processGO:00091161790.035
cellular response to insulin stimulusGO:0032869810.034
metal ion homeostasisGO:00550651860.034
tetrapyrrole metabolic processGO:0033013110.034
regulation of tolerance inductionGO:000264320.034
regulation of protein processingGO:0070613500.033
blood vessel morphogenesisGO:0048514580.033
progesterone metabolic processGO:004244880.033
cellular response to nitrogen compoundGO:19016992100.033
cellular response to organic cyclic compoundGO:00714072020.033
regenerationGO:00310991630.033
catecholamine biosynthetic processGO:004242390.033
nucleotide catabolic processGO:00091661390.033
carboxylic acid biosynthetic processGO:0046394830.033
phenol containing compound biosynthetic processGO:004618990.033
positive regulation of extracellular matrix constituent secretionGO:000333120.032
cellular response to campGO:0071320260.032
ribonucleotide catabolic processGO:00092611360.031
innate immune responseGO:0045087350.031
response to foodGO:0032094270.031
multicellular organismal signalingGO:0035637440.031
gland developmentGO:00487321550.031
regulation of reactive oxygen species biosynthetic processGO:190342650.031
negative regulation of molecular functionGO:00440921330.031
regulation of excretionGO:0044062210.031
response to toxic substanceGO:00096361330.030
purine ribonucleoside triphosphate metabolic processGO:00092051400.030
negative regulation of gene expressionGO:00106291990.030
negative regulation of phosphate metabolic processGO:0045936800.030
protein targetingGO:0006605610.029
steroid biosynthetic processGO:0006694480.029
organic hydroxy compound biosynthetic processGO:1901617510.029
regulation of cell growthGO:0001558850.029
regulation of fibrinolysisGO:005191720.029
regulation of long term neuronal synaptic plasticityGO:0048169150.029
regulation of cellular protein metabolic processGO:00322682670.028
regulation of extracellular matrix constituent secretionGO:000333020.028
regulation of norepinephrine secretionGO:0014061150.028
apoptotic processGO:00069153810.028
exogenous drug catabolic processGO:004273810.028
purine nucleoside triphosphate metabolic processGO:00091441410.027
carbohydrate derivative biosynthetic processGO:19011371240.027
response to cytokineGO:00340972150.027
positive regulation of hydrolase activityGO:0051345860.027
toxin catabolic processGO:000940710.027
negative regulation of protein metabolic processGO:00512481140.027
negative regulation of phosphorus metabolic processGO:0010563800.026
regulation of catalytic activityGO:00507903040.026
organic anion transportGO:00157111320.025
purine containing compound catabolic processGO:00725231380.025
positive regulation of cellular biosynthetic processGO:00313282950.025
ribonucleoside triphosphate metabolic processGO:00091991410.025
cellular amine metabolic processGO:0044106380.025
regulation of blood pressureGO:0008217830.025
purine nucleoside triphosphate catabolic processGO:00091461220.025
divalent metal ion transportGO:00708381320.025
cellular metal ion homeostasisGO:00068751720.024
intracellular transportGO:00469071850.024
fatty acid biosynthetic processGO:0006633330.024
regulation of anatomical structure morphogenesisGO:00226031410.024
cellular response to organonitrogen compoundGO:00714171970.024
cellular macromolecule localizationGO:00707271220.024
cation homeostasisGO:00550801950.024
regulation of atpase activityGO:004346270.023
positive regulation of cell projection organizationGO:00313461110.023
response to insecticideGO:0017085210.023
cellular response to glucocorticoid stimulusGO:0071385680.023
cellular ion homeostasisGO:00068731840.023
response to amino acidGO:0043200750.023
acylglycerol metabolic processGO:0006639210.023
chemical homeostasisGO:00488782920.023
regulation of calcium ion transportGO:0051924770.023
cellular response to oxygen containing compoundGO:19017013860.023
g protein coupled receptor signaling pathwayGO:00071862420.023
protein transportGO:00150311320.022
purine ribonucleoside monophosphate catabolic processGO:0009169550.022
proteolysisGO:00065081750.022
negative regulation of protein maturationGO:1903318470.022
ribonucleoside triphosphate catabolic processGO:00092031220.022
cellular cation homeostasisGO:00300031800.022
lipid storageGO:001991510.022
stress activated protein kinase signaling cascadeGO:0031098370.022
positive regulation of molecular functionGO:00440932300.022
synaptic transmissionGO:00072682350.022
response to ethanolGO:00454711620.022
response to ionizing radiationGO:0010212590.022
cellular response to corticosteroid stimulusGO:0071384690.021
protein complex assemblyGO:00064612630.021
positive regulation of reactive oxygen species biosynthetic processGO:190342820.021
response to cadmium ionGO:0046686350.021
growthGO:00400071650.021
regulation of phosphate metabolic processGO:00192203490.020
regulation of homeostatic processGO:00328441010.020
oxidative demethylationGO:007098920.020
response to carbohydrateGO:00097431830.020
transcription dna templatedGO:00063513770.020
alcohol metabolic processGO:0006066770.020
dopamine metabolic processGO:0042417120.020
regulation of proteolysisGO:0030162660.020
blood vessel developmentGO:0001568690.019
regulation of system processGO:00440572080.019
regulation of nucleotide metabolic processGO:00061401170.019
c21 steroid hormone metabolic processGO:0008207140.019
response to fatty acidGO:0070542650.019
regulation of peptidase activityGO:0052547550.019
mononuclear cell migrationGO:007167430.019
negative regulation of apoptotic processGO:00430661810.019
amino acid transportGO:0006865700.019
leydig cell differentiationGO:003332780.019
immune system processGO:00023762040.019
positive regulation of neuron projection developmentGO:0010976990.019
regulation of gtpase activityGO:0043087570.019
maintenance of locationGO:0051235170.019
negative regulation of macromolecule metabolic processGO:00106052600.019
cation transportGO:00068123820.019
nucleic acid templated transcriptionGO:00976593790.019
reproductionGO:00000032450.018
phenylpropanoid catabolic processGO:004627130.018
calcitriol biosynthetic process from calciolGO:003637820.018
response to ddtGO:004668010.018
regulation of catabolic processGO:00098941130.018
cellular component biogenesisGO:00440853680.018
retinoid metabolic processGO:0001523240.018
immune responseGO:00069551040.018
regulation of growthGO:00400081050.017
terpenoid metabolic processGO:0006721370.017
regulation of cyclic nucleotide biosynthetic processGO:0030802450.017
response to estrogenGO:00436272320.017
brain developmentGO:00074202470.017
regulation of body fluid levelsGO:0050878900.017
positive regulation of biosynthetic processGO:00098913190.017
monocarboxylic acid biosynthetic processGO:0072330480.017
cellular homeostasisGO:00197252520.017
demethylationGO:007098870.017
carbohydrate metabolic processGO:00059751300.017
porphyrin containing compound metabolic processGO:000677880.017
glycosyl compound catabolic processGO:19016581260.016
cellular response to cytokine stimulusGO:00713451270.016
negative regulation of programmed cell deathGO:00430691830.016
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.016
regulation of cellular ketone metabolic processGO:0010565270.016
intracellular protein transportGO:0006886790.016
acute phase responseGO:0006953200.016
protein processingGO:0016485680.016
regulation of blood circulationGO:19035221100.016
regulation of multicellular organismal developmentGO:20000263760.016
regulation of protein maturationGO:1903317500.016
establishment of protein localization to organelleGO:0072594440.016
regulation of transcription dna templatedGO:00063553740.016
regulation of cell projection organizationGO:00313441750.016
estrogen metabolic processGO:0008210110.016
toxin metabolic processGO:000940490.016
cytoplasmic transportGO:00164821150.016
hormone metabolic processGO:0042445690.016
regulation of cellular catabolic processGO:00313291010.015
response to inorganic substanceGO:00100353770.015
follicle stimulating hormone signaling pathwayGO:004269950.015
regulation of cellular amino acid metabolic processGO:000652120.015
central nervous system developmentGO:00074173110.015
testosterone biosynthetic processGO:006137050.015
negative regulation of catalytic activityGO:00430861030.015
nucleoside monophosphate catabolic processGO:0009125560.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
cell growthGO:00160491040.015
gtp metabolic processGO:0046039720.015
positive regulation of reactive oxygen species metabolic processGO:2000379160.015
response to starvationGO:0042594590.015
cellular response to peptideGO:19016531330.015
cellular response to endogenous stimulusGO:00714953770.015
response to prostaglandin fGO:003469640.014
response to muscle activity involved in regulation of muscle adaptationGO:001487320.014
sodium ion homeostasisGO:0055078230.014
acid secretionGO:0046717480.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
carboxylic acid transportGO:00469421150.014
response to interferon gammaGO:0034341200.014
monosaccharide metabolic processGO:0005996610.014
positive regulation of rna biosynthetic processGO:19026801970.014
response to acetateGO:001003430.014
regulation of amine transportGO:0051952540.014
drinking behaviorGO:0042756110.014
response to mercury ionGO:0046689150.013
circulatory system processGO:00030131830.013
reactive nitrogen species metabolic processGO:200105710.013
regulation of neurogenesisGO:00507672470.013
response to methanolGO:003398610.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.013
positive regulation of nucleotide catabolic processGO:0030813530.013
regulation of ovulationGO:006027820.013
positive regulation of catalytic activityGO:00430851840.013
regulation of hormone levelsGO:00108171870.013
small molecule biosynthetic processGO:00442831240.013
regulation of renal sodium excretionGO:0035813200.013
action potentialGO:0001508540.013
establishment of protein localizationGO:00451841410.013
negative regulation of fibrinolysisGO:005191820.013
catecholamine metabolic processGO:0006584190.013
calcium ion transportGO:00068161310.013
regulation of nucleotide catabolic processGO:0030811650.013
intracellular signal transductionGO:00355563140.012
protein n linked glycosylationGO:000648720.012
4 nitrophenol metabolic processGO:001896010.012
cellular response to stressGO:00335542690.012
purine nucleoside monophosphate catabolic processGO:0009128550.012
positive regulation of gene expressionGO:00106282440.012
norepinephrine transportGO:0015874180.012
regulation of nucleoside metabolic processGO:0009118660.012
regulation of circadian sleep wake cycle sleepGO:0045187180.012
positive regulation of calcium ion transportGO:0051928360.012
catechol containing compound metabolic processGO:0009712190.012
alpha amino acid metabolic processGO:1901605710.012
cyclic nucleotide metabolic processGO:0009187800.012
organic hydroxy compound transportGO:0015850770.012
regulation of nervous system developmentGO:00519602640.012
macromolecular complex subunit organizationGO:00439333390.012
brain renin angiotensin systemGO:000203530.012
icosanoid biosynthetic processGO:0046456180.012
regulation of phosphorus metabolic processGO:00511743490.012
hexose metabolic processGO:0019318580.012
artery smooth muscle contractionGO:001482440.012
protein localizationGO:00081041910.012
secretion by cellGO:00329402480.012
positive regulation of nitric oxide biosynthetic processGO:0045429140.012
response to vitamin aGO:0033189360.012
positive regulation of neuron differentiationGO:00456661260.012
positive regulation of tolerance inductionGO:000264510.011
response to platinum ionGO:007054140.011
neuron developmentGO:00486662860.011
response to gonadotropinGO:0034698340.011
nitrogen compound transportGO:00717052290.011
response to amphetamineGO:0001975250.011
isoprenoid metabolic processGO:0006720450.011
positive regulation of cell developmentGO:00107201760.011
organic acid transportGO:00158491160.011
negative regulation of hydrolase activityGO:0051346520.011
response to testosteroneGO:0033574550.011
regulation of cellular component organizationGO:00511283680.011
positive regulation of blood coagulationGO:003019440.011
regulation of endopeptidase activityGO:0052548510.011
neuron projection regenerationGO:0031102350.011
amide transportGO:00428861050.011
regulation of rna metabolic processGO:00512523910.011
negative regulation of proteolysisGO:0045861410.011
muscle structure developmentGO:0061061870.011
regulation of rna biosynthetic processGO:20011413810.011
regulation of nucleic acid templated transcriptionGO:19035063800.011
smooth muscle cell apoptotic processGO:003439070.011
guanosine containing compound metabolic processGO:1901068740.011
phosphatidylethanolamine metabolic processGO:004633710.011
positive regulation of blood pressureGO:0045777310.011
atp metabolic processGO:0046034720.011
rna metabolic processGO:00160704060.011
ribonucleoside monophosphate catabolic processGO:0009158550.010
hormone biosynthetic processGO:0042446250.010
response to radiationGO:00093141370.010
tolerance induction dependent upon immune responseGO:000246120.010
response to corticosteroneGO:0051412400.010
response to oxidative stressGO:00069791860.010
regulation of lipid biosynthetic processGO:0046890380.010
cellular carbohydrate metabolic processGO:0044262720.010
regulation of ion homeostasisGO:2000021630.010
macromolecular complex assemblyGO:00650032730.010
regulation of secretion by cellGO:19035302080.010
cellular response to starvationGO:0009267270.010

A1i3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.053
disease of metabolismDOID:001466700.053
musculoskeletal system diseaseDOID:1700.042
disease of anatomical entityDOID:700.042
cardiovascular system diseaseDOID:128700.036
artery diseaseDOID:005082800.028
vascular diseaseDOID:17800.028
steroid inherited metabolic disorderDOID:170100.014
congenital adrenal hyperplasiaDOID:005081100.014
lipid metabolism disorderDOID:314600.014
heart diseaseDOID:11400.013