Rattus norvegicus

0 known processes

Oplah

5-oxoprolinase (ATP-hydrolysing)

(Aliases: MGC105359)

Oplah biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.475
carboxylic acid biosynthetic processGO:0046394830.355
organic acid biosynthetic processGO:0016053830.288
carboxylic acid metabolic processGO:00197522890.235
cellular amino acid biosynthetic processGO:0008652320.202
carboxylic acid catabolic processGO:0046395490.197
monocarboxylic acid metabolic processGO:00327871520.194
response to nutrient levelsGO:00316673700.164
organic acid catabolic processGO:0016054490.163
catabolic processGO:00090563510.158
oxoacid metabolic processGO:00434362900.155
small molecule biosynthetic processGO:00442831240.121
organonitrogen compound biosynthetic processGO:19015661670.110
oxidation reduction processGO:00551143040.108
single organism biosynthetic processGO:00447113420.101
fatty acid metabolic processGO:0006631990.100
fatty acid beta oxidationGO:0006635220.100
cellular lipid catabolic processGO:0044242370.086
cellular lipid metabolic processGO:00442552080.082
organic substance catabolic processGO:19015753160.080
single organism catabolic processGO:00447122830.076
response to extracellular stimulusGO:00099913800.074
cellular catabolic processGO:00442482950.072
monocarboxylic acid catabolic processGO:0072329280.072
response to nutrientGO:00075842480.071
neurological system processGO:00508772190.071
organophosphate metabolic processGO:00196373700.071
negative regulation of multicellular organismal processGO:00512412030.061
lipid metabolic processGO:00066292830.061
regulation of intracellular signal transductionGO:19025312180.060
response to other organismGO:00517072200.058
coenzyme metabolic processGO:0006732860.058
protein complex assemblyGO:00064612630.056
regulation of neurogenesisGO:00507672470.053
cellular response to hormone stimulusGO:00328702470.048
fatty acid oxidationGO:0019395290.047
cellular component assemblyGO:00226073600.046
small molecule catabolic processGO:0044282590.046
response to glucocorticoidGO:00513842230.046
positive regulation of multicellular organismal processGO:00512403870.046
response to external biotic stimulusGO:00432072210.045
ion transmembrane transportGO:00342203650.044
protein homooligomerizationGO:0051260910.044
cellular component biogenesisGO:00440853680.043
lipid modificationGO:0030258520.043
regulation of cell developmentGO:00602842630.042
transmembrane transportGO:00550854120.041
regulation of nervous system developmentGO:00519602640.041
cellular amino acid metabolic processGO:00065201070.041
nucleotide metabolic processGO:00091172790.040
protein homotetramerizationGO:0051289250.039
cellular response to oxygen containing compoundGO:19017013860.037
nucleoside phosphate metabolic processGO:00067532830.037
cation transportGO:00068123820.037
response to acid chemicalGO:00011012220.037
gland developmentGO:00487321550.037
nucleobase containing small molecule metabolic processGO:00550863160.037
cellular protein localizationGO:00346131220.037
macromolecular complex subunit organizationGO:00439333390.037
protein oligomerizationGO:00512591910.037
cellular amine metabolic processGO:0044106380.036
negative regulation of cell differentiationGO:0045596990.036
regulation of molecular functionGO:00650093980.036
organophosphate biosynthetic processGO:00904071430.035
negative regulation of metabolic processGO:00098923310.034
brain developmentGO:00074202470.033
macromolecular complex assemblyGO:00650032730.033
regulation of cellular localizationGO:00603412630.032
pyridine containing compound metabolic processGO:0072524320.032
cellular component morphogenesisGO:00329891550.032
response to ethanolGO:00454711620.031
positive regulation of cellular component organizationGO:00511302000.030
negative regulation of macromolecule metabolic processGO:00106052600.030
response to peptideGO:19016522920.030
intracellular signal transductionGO:00355563140.030
negative regulation of developmental processGO:00510931250.030
fatty acid catabolic processGO:0009062260.030
response to biotic stimulusGO:00096072260.029
chemical homeostasisGO:00488782920.029
regulation of cellular component organizationGO:00511283680.029
nicotinamide nucleotide metabolic processGO:0046496280.029
response to vitaminGO:00332731310.029
regulation of cell differentiationGO:00455953200.028
cation transmembrane transportGO:00986552630.028
response to lipopolysaccharideGO:00324961910.028
carbohydrate derivative biosynthetic processGO:19011371240.028
multicellular organismal reproductive processGO:00486092330.028
lipid biosynthetic processGO:00086101280.028
signal releaseGO:00230611450.028
protein tetramerizationGO:0051262380.028
protein phosphorylationGO:00064683450.028
dicarboxylic acid catabolic processGO:004364910.027
regulation of signal transductionGO:00099663180.027
urogenital system developmentGO:0001655780.027
neuron differentiationGO:00301823680.027
secretionGO:00469033070.027
regulation of cell projection organizationGO:00313441750.027
cellular response to organic cyclic compoundGO:00714072020.027
positive regulation of nitrogen compound metabolic processGO:00511733340.027
positive regulation of biosynthetic processGO:00098913190.026
purine nucleotide metabolic processGO:00061632290.026
purine ribonucleotide metabolic processGO:00091502270.026
metal ion homeostasisGO:00550651860.026
monovalent inorganic cation transportGO:00156721720.026
nucleic acid templated transcriptionGO:00976593790.026
regulation of multicellular organismal developmentGO:20000263760.025
rna metabolic processGO:00160704060.025
protein complex biogenesisGO:00702712630.025
metal ion transportGO:00300012890.025
regulation of neuron differentiationGO:00456642080.025
response to hyperoxiaGO:0055093450.025
protein complex subunit organizationGO:00718223020.025
cell projection morphogenesisGO:00488581230.025
purine containing compound metabolic processGO:00725212530.025
regulation of phosphorylationGO:00423252480.025
organonitrogen compound catabolic processGO:19015651790.025
cellular response to lipidGO:00713962010.024
transcription dna templatedGO:00063513770.024
monocarboxylic acid biosynthetic processGO:0072330480.024
central nervous system developmentGO:00074173110.024
positive regulation of phosphate metabolic processGO:00459372620.024
glutamate catabolic processGO:000653810.024
sensory perceptionGO:00076001010.024
regulation of secretion by cellGO:19035302080.024
tube developmentGO:0035295890.024
carbohydrate derivative metabolic processGO:19011353460.024
reproductive processGO:00224143720.023
apoptotic processGO:00069153810.023
inorganic cation transmembrane transportGO:00986622020.023
cell cell signalingGO:00072673350.023
negative regulation of cellular biosynthetic processGO:00313271610.023
regulation of neuron projection developmentGO:00109751610.023
neuron projection developmentGO:00311752730.023
homeostatic processGO:00425923310.023
multicellular organism reproductionGO:00325042330.023
regulation of canonical wnt signaling pathwayGO:006082840.023
negative regulation of cellular metabolic processGO:00313242810.023
positive regulation of nervous system developmentGO:00519621780.023
cellular amino acid catabolic processGO:0009063210.023
single organism reproductive processGO:00447022970.023
cell projection organizationGO:00300303020.022
cardiovascular system developmentGO:00723581340.022
positive regulation of cellular amine metabolic processGO:003324030.022
positive regulation of phosphorus metabolic processGO:00105622620.022
negative regulation of biosynthetic processGO:00098901680.022
programmed cell deathGO:00125013920.022
organic hydroxy compound metabolic processGO:19016151150.022
cell morphogenesis involved in differentiationGO:00009041190.021
lipid catabolic processGO:0016042460.021
nucleoside phosphate biosynthetic processGO:19012931020.021
response to corticosteroidGO:00319602350.021
response to organophosphorusGO:00466831020.021
cofactor metabolic processGO:0051186950.021
cofactor biosynthetic processGO:0051188280.021
hexose metabolic processGO:0019318580.021
inorganic ion transmembrane transportGO:00986602290.021
cellular response to peptide hormone stimulusGO:00713751200.021
response to cytokineGO:00340972150.021
positive regulation of intracellular signal transductionGO:19025331380.021
regulation of cellular protein metabolic processGO:00322682670.020
cellular response to endogenous stimulusGO:00714953770.020
regulation of hormone levelsGO:00108171870.020
immune system processGO:00023762040.020
response to molecule of bacterial originGO:00022371940.020
cellular macromolecule localizationGO:00707271220.020
circulatory system developmentGO:00723591340.020
regulation of protein metabolic processGO:00512462890.020
response to mechanical stimulusGO:00096121340.020
positive regulation of cellular protein metabolic processGO:00322701670.020
response to campGO:0051591910.020
positive regulation of cellular biosynthetic processGO:00313282950.020
positive regulation of protein metabolic processGO:00512471780.019
cellular response to nitrogen compoundGO:19016992100.019
negative regulation of signalingGO:00230571570.019
nucleoside monophosphate metabolic processGO:0009123930.019
hepaticobiliary system developmentGO:0061008900.019
regulation of programmed cell deathGO:00430673410.019
cellular response to stressGO:00335542690.019
positive regulation of developmental processGO:00510942830.019
single organism membrane organizationGO:0044802740.019
regulation of cell proliferationGO:00421273590.019
multicellular organism growthGO:003526410.019
nucleotide biosynthetic processGO:0009165980.019
positive regulation of cellular amino acid metabolic processGO:004576410.018
regenerationGO:00310991630.018
negative regulation of programmed cell deathGO:00430691830.018
negative regulation of cell communicationGO:00106481580.018
regulation of phosphorus metabolic processGO:00511743490.018
regulation of cellular amine metabolic processGO:003323880.018
positive regulation of phosphorylationGO:00423271770.018
regulation of phosphate metabolic processGO:00192203490.018
regulation of apoptotic processGO:00429813350.018
multi organism reproductive processGO:00447032620.018
gastrulationGO:000736920.018
blood circulationGO:00080151830.018
response to insulinGO:00328681330.018
nitrogen compound transportGO:00717052290.018
synaptic transmissionGO:00072682350.018
cellular ketone metabolic processGO:0042180510.018
regulation of cellular amino acid metabolic processGO:000652120.018
digestive system developmentGO:0055123410.017
multicellular organismal signalingGO:0035637440.017
positive regulation of transportGO:00510502450.017
macromolecule localizationGO:00330362520.017
alpha amino acid catabolic processGO:1901606200.017
single organism carbohydrate metabolic processGO:00447231180.017
digestive tract developmentGO:0048565390.017
carbohydrate metabolic processGO:00059751300.017
defense responseGO:00069521940.017
nadp metabolic processGO:0006739130.017
cellular response to acid chemicalGO:0071229750.017
response to peptide hormoneGO:00434342780.017
response to oxygen levelsGO:00704822650.017
purine nucleotide biosynthetic processGO:0006164830.017
heart morphogenesisGO:000300730.017
regulation of proteasomal protein catabolic processGO:006113640.017
neuron developmentGO:00486662860.017
negative regulation of cell deathGO:00605482290.017
positive regulation of ion transportGO:0043270940.016
rna biosynthetic processGO:00327743800.016
growthGO:00400071650.016
liver developmentGO:0001889900.016
ion homeostasisGO:00508012120.016
purine nucleoside metabolic processGO:00422781690.016
response to purine containing compoundGO:00140741260.016
behaviorGO:00076102050.016
regulation of response to stressGO:00801341260.016
response to retinoic acidGO:0032526630.016
muscle contractionGO:0006936880.016
ribonucleotide metabolic processGO:00092592310.016
negative regulation of molecular functionGO:00440921330.016
regulation of protein modification processGO:00313991940.016
amine metabolic processGO:0009308380.016
regulation of ion transportGO:00432692450.016
localization of cellGO:00516742020.016
cellular ion homeostasisGO:00068731840.015
anion transportGO:00068201780.015
organic acid transportGO:00158491160.015
acetyl coa metabolic processGO:0006084170.015
cellular homeostasisGO:00197252520.015
positive regulation of signalingGO:00230562700.015
amine catabolic processGO:000931090.015
locomotionGO:00400112370.015
response to testosteroneGO:0033574550.015
positive regulation of cell differentiationGO:00455972170.015
positive regulation of molecular functionGO:00440932300.015
inflammatory responseGO:00069541500.015
regulation of secretionGO:00510462240.015
secretion by cellGO:00329402480.015
reproductionGO:00000032450.015
axonogenesisGO:0007409710.015
acetate metabolic processGO:000608320.015
positive regulation of protein modification processGO:00314011420.015
neuron neuron synaptic transmissionGO:0007270600.015
cellular response to drugGO:0035690300.015
negative regulation of apoptotic processGO:00430661810.015
ribose phosphate metabolic processGO:00196932350.015
neuron projection morphogenesisGO:00488121220.015
positive regulation of response to stimulusGO:00485842850.015
protein localizationGO:00081041910.015
regulation of nucleic acid templated transcriptionGO:19035063800.014
positive regulation of transcription dna templatedGO:00458931970.014
response to ketoneGO:19016541820.014
positive regulation of cell developmentGO:00107201760.014
circulatory system processGO:00030131830.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
tissue developmentGO:00098882520.014
negative regulation of nervous system developmentGO:0051961790.014
ribonucleoside metabolic processGO:00091191740.014
cellular calcium ion homeostasisGO:00068741600.014
positive regulation of protein phosphorylationGO:00019341350.014
response to inorganic substanceGO:00100353770.014
alpha amino acid metabolic processGO:1901605710.014
regulation of cellular ketone metabolic processGO:0010565270.014
proteolysisGO:00065081750.014
positive regulation of cell projection organizationGO:00313461110.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
negative regulation of cellular component organizationGO:0051129830.013
positive regulation of neurogenesisGO:00507691650.013
calcium ion homeostasisGO:00550741620.013
small gtpase mediated signal transductionGO:0007264360.013
regulation of catabolic processGO:00098941130.013
hormone transportGO:00099141210.013
agingGO:00075682410.013
head developmentGO:00603222470.013
g protein coupled receptor signaling pathwayGO:00071862420.013
renal system developmentGO:0072001670.013
response to fatty acidGO:0070542650.013
response to vitamin aGO:0033189360.013
developmental inductionGO:003112820.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
divalent inorganic cation homeostasisGO:00725071650.013
cellular chemical homeostasisGO:00550822470.013
regulation of system processGO:00440572080.013
negative regulation of neuron projection developmentGO:0010977460.013
regulation of transcription dna templatedGO:00063553740.013
organic anion transportGO:00157111320.013
membrane organizationGO:0061024940.013
regulation of catalytic activityGO:00507903040.013
cellular component movementGO:00069282480.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
intracellular transportGO:00469071850.013
protein localization to membraneGO:0072657360.013
regulation of nucleotide metabolic processGO:00061401170.013
regulation of rna biosynthetic processGO:20011413810.012
cyclic nucleotide biosynthetic processGO:0009190630.012
cellular response to peptideGO:19016531330.012
positive regulation of neuron differentiationGO:00456661260.012
chromosome segregationGO:000705920.012
defense response to gram negative bacteriumGO:005082930.012
muscle system processGO:00030121150.012
negative regulation of neurogenesisGO:0050768780.012
cation homeostasisGO:00550801950.012
regulation of blood pressureGO:0008217830.012
heterocycle catabolic processGO:00467001670.012
epithelium developmentGO:0060429960.012
positive regulation of homeostatic processGO:0032846490.012
negative regulation of cell proliferationGO:00082851190.012
positive regulation of catalytic activityGO:00430851840.012
heart developmentGO:0007507720.012
regulation of rna metabolic processGO:00512523910.012
response to alkaloidGO:00432791320.012
response to radiationGO:00093141370.012
negative regulation of gene expressionGO:00106291990.012
ras protein signal transductionGO:0007265290.012
negative regulation of synaptic transmissionGO:0050805290.012
glycosyl compound metabolic processGO:19016571820.011
lipid transportGO:0006869610.011
gamete generationGO:00072761240.011
carboxylic acid transportGO:00469421150.011
regulation of membrane potentialGO:00423911100.011
regulation of axonogenesisGO:0050770370.011
negative regulation of phosphorus metabolic processGO:0010563800.011
regulation of lipid metabolic processGO:0019216680.011
response to bacteriumGO:00096172000.011
negative regulation of cellular protein metabolic processGO:00322691060.011
regulation of body fluid levelsGO:0050878900.011
pyridine nucleotide metabolic processGO:0019362280.011
negative regulation of signal transductionGO:0009968830.011
single organism cellular localizationGO:19025801020.011
lipid oxidationGO:0034440300.011
negative regulation of transcription dna templatedGO:00458921160.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
negative regulation of response to stimulusGO:00485851550.011
response to hypoxiaGO:00016662310.011
negative regulation of catalytic activityGO:00430861030.011
oligopeptide transportGO:000685740.011
response to decreased oxygen levelsGO:00362932370.011
purine ribonucleoside metabolic processGO:00461281680.011
regulation of hormone secretionGO:00468831060.011
establishment of planar polarityGO:000173610.011
response to woundingGO:00096112540.011
developmental growthGO:00485891000.011
cellular response to alcoholGO:0097306870.011
positive regulation of cell proliferationGO:00082842490.011
positive regulation of rna biosynthetic processGO:19026801970.011
oxidoreduction coenzyme metabolic processGO:0006733310.011
single organism intracellular transportGO:19025821660.011
negative regulation of secretion by cellGO:1903531720.011
actin filament based processGO:0030029860.011
dephosphorylationGO:0016311980.011
cell motilityGO:00488702020.011
cytoplasmic transportGO:00164821150.011
regulation of immune system processGO:00026821230.011
sex differentiationGO:00075481130.011
positive regulation of cell deathGO:00109421840.011
nucleoside metabolic processGO:00091161790.011
regulation of cellular response to stressGO:0080135490.011
positive regulation of transferase activityGO:0051347810.011
positive regulation of cellular catabolic processGO:0031331710.011
axon developmentGO:0061564960.011
cell cycle checkpointGO:000007520.011
cellular biogenic amine metabolic processGO:0006576300.011
cell migrationGO:00164771970.010
anion transmembrane transportGO:0098656770.010
positive regulation of secretion by cellGO:19035321280.010
developmental process involved in reproductionGO:00030061590.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
mechanoreceptor differentiationGO:004249020.010
sulfur compound biosynthetic processGO:0044272190.010
regulation of transferase activityGO:00513381230.010
cellular metal ion homeostasisGO:00068751720.010
purine ribonucleotide biosynthetic processGO:0009152810.010
sensory organ developmentGO:0007423740.010
thioester biosynthetic processGO:003538470.010
cellular nitrogen compound catabolic processGO:00442701630.010
positive regulation of catabolic processGO:0009896780.010
response to osmotic stressGO:0006970420.010
synaptic growth at neuromuscular junctionGO:005112410.010
cellular response to cytokine stimulusGO:00713451270.010
very long chain fatty acid metabolic processGO:000003830.010
regulation of homeostatic processGO:00328441010.010
spindle organizationGO:000705120.010
neuron projection regenerationGO:0031102350.010

Oplah disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.045
disease of metabolismDOID:001466700.045
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
musculoskeletal system diseaseDOID:1700.014
central nervous system diseaseDOID:33100.012