Rattus norvegicus

0 known processes

Spink8

serine peptidase inhibitor, Kazal type 8

(Aliases: RGD1307150)

Spink8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure morphogenesisGO:00096532980.083
positive regulation of multicellular organismal processGO:00512403870.083
response to temperature stimulusGO:0009266940.078
response to woundingGO:00096112540.078
regulation of phosphorus metabolic processGO:00511743490.076
response to oxygen levelsGO:00704822650.071
programmed cell deathGO:00125013920.068
regulation of programmed cell deathGO:00430673410.066
cellular component biogenesisGO:00440853680.062
positive regulation of cellular component organizationGO:00511302000.057
positive regulation of response to stimulusGO:00485842850.057
biological adhesionGO:00226101100.056
reproductive processGO:00224143720.055
tissue developmentGO:00098882520.055
cellular component assemblyGO:00226073600.055
cellular component morphogenesisGO:00329891550.054
cell adhesionGO:00071551100.053
reproductionGO:00000032450.049
organ morphogenesisGO:0009887750.048
multicellular organism reproductionGO:00325042330.048
monovalent inorganic cation transportGO:00156721720.048
regulation of apoptotic processGO:00429813350.046
cation transportGO:00068123820.046
regulation of cellular component organizationGO:00511283680.044
striated muscle tissue developmentGO:0014706580.044
single organism reproductive processGO:00447022970.043
multicellular organismal reproductive processGO:00486092330.041
secretionGO:00469033070.041
signal transduction by phosphorylationGO:00230141440.040
response to peptideGO:19016522920.040
positive regulation of biosynthetic processGO:00098913190.039
response to inorganic substanceGO:00100353770.039
gland developmentGO:00487321550.038
regulation of hormone levelsGO:00108171870.038
cell projection organizationGO:00300303020.037
single organismal cell cell adhesionGO:0016337420.037
single organism biosynthetic processGO:00447113420.037
macromolecular complex subunit organizationGO:00439333390.037
organelle organizationGO:00069962660.036
metal ion transportGO:00300012890.036
muscle system processGO:00030121150.035
transmembrane transportGO:00550854120.035
cellular response to stressGO:00335542690.035
positive regulation of cell proliferationGO:00082842490.035
regulation of body fluid levelsGO:0050878900.034
intracellular signal transductionGO:00355563140.034
reproductive system developmentGO:00614581280.034
growthGO:00400071650.034
positive regulation of phosphate metabolic processGO:00459372620.033
anion transportGO:00068201780.033
organic anion transportGO:00157111320.033
secretion by cellGO:00329402480.032
neuron projection developmentGO:00311752730.032
regulation of multicellular organismal developmentGO:20000263760.032
liver developmentGO:0001889900.032
neuron developmentGO:00486662860.032
positive regulation of transportGO:00510502450.032
response to extracellular stimulusGO:00099913800.031
organic cyclic compound catabolic processGO:19013611750.031
positive regulation of secretionGO:00510471400.031
nucleic acid templated transcriptionGO:00976593790.030
positive regulation of macromolecule biosynthetic processGO:00105572470.030
regulation of anatomical structure morphogenesisGO:00226031410.030
carboxylic acid transportGO:00469421150.030
negative regulation of programmed cell deathGO:00430691830.030
positive regulation of signalingGO:00230562700.029
regulation of cell proliferationGO:00421273590.029
sodium ion transportGO:0006814820.028
sulfur compound biosynthetic processGO:0044272190.028
head developmentGO:00603222470.028
cell growthGO:00160491040.027
hormone transportGO:00099141210.027
purine nucleoside metabolic processGO:00422781690.027
regulation of response to external stimulusGO:00321011060.027
response to peptide hormoneGO:00434342780.026
cation transmembrane transportGO:00986552630.026
single organism cell adhesionGO:0098602460.026
cell morphogenesisGO:00009021420.026
protein complex subunit organizationGO:00718223020.026
hepaticobiliary system developmentGO:0061008900.026
developmental process involved in reproductionGO:00030061590.026
muscle tissue developmentGO:0060537580.026
regulation of phosphate metabolic processGO:00192203490.025
sensory organ developmentGO:0007423740.025
behaviorGO:00076102050.025
sexual reproductionGO:00199531480.025
homeostatic processGO:00425923310.025
ribose phosphate metabolic processGO:00196932350.025
organophosphate metabolic processGO:00196373700.025
regulation of catalytic activityGO:00507903040.024
hepatocyte proliferationGO:007257430.024
brain developmentGO:00074202470.024
positive regulation of cell communicationGO:00106472710.024
regulation of cell developmentGO:00602842630.024
response to estrogenGO:00436272320.023
negative regulation of cell deathGO:00605482290.023
response to mechanical stimulusGO:00096121340.023
organic acid biosynthetic processGO:0016053830.022
regulation of establishment of planar polarityGO:009017520.022
purine containing compound catabolic processGO:00725231380.022
response to hypoxiaGO:00016662310.022
anterior posterior pattern specificationGO:000995210.022
cellular chemical homeostasisGO:00550822470.022
positive regulation of signal transductionGO:00099671750.022
response to decreased oxygen levelsGO:00362932370.022
carboxylic acid metabolic processGO:00197522890.022
response to heatGO:0009408600.021
epithelium developmentGO:0060429960.021
neuron differentiationGO:00301823680.021
positive regulation of cellular biosynthetic processGO:00313282950.021
muscle filament slidingGO:003004920.021
cation homeostasisGO:00550801950.021
oxoacid metabolic processGO:00434362900.021
carbohydrate derivative catabolic processGO:19011361470.020
fibrinolysisGO:004273020.020
epithelial cell proliferationGO:0050673540.020
protein phosphorylationGO:00064683450.020
regulation of response to stressGO:00801341260.020
macromolecular complex assemblyGO:00650032730.020
muscle structure developmentGO:0061061870.020
actin filament based processGO:0030029860.020
rhythmic processGO:00485111560.020
regulation of rna metabolic processGO:00512523910.020
acrosome assemblyGO:000167530.020
cellular response to endogenous stimulusGO:00714953770.020
regulation of neuron projection developmentGO:00109751610.020
negative regulation of developmental processGO:00510931250.020
response to nutrient levelsGO:00316673700.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
response to carbohydrateGO:00097431830.020
organic acid metabolic processGO:00060822920.020
potassium ion transportGO:0006813970.020
catabolic processGO:00090563510.020
central nervous system developmentGO:00074173110.020
intestinal absorptionGO:005089230.020
positive regulation of cell differentiationGO:00455972170.019
positive regulation of intracellular signal transductionGO:19025331380.019
regulation of epithelial cell proliferationGO:0050678490.019
purine ribonucleotide metabolic processGO:00091502270.019
negative regulation of apoptotic processGO:00430661810.019
cellular metal ion homeostasisGO:00068751720.019
regulation of transcription dna templatedGO:00063553740.019
single organism carbohydrate metabolic processGO:00447231180.019
immune system processGO:00023762040.019
monocarboxylic acid metabolic processGO:00327871520.019
inorganic cation transmembrane transportGO:00986622020.019
negative regulation of signalingGO:00230571570.019
organonitrogen compound catabolic processGO:19015651790.019
epithelial cell differentiationGO:0030855710.019
regulation of secretion by cellGO:19035302080.018
regulation of response to woundingGO:1903034690.018
macromolecule localizationGO:00330362520.018
positive regulation of phosphorus metabolic processGO:00105622620.018
protein complex assemblyGO:00064612630.018
apoptotic processGO:00069153810.018
cell cycleGO:00070491010.018
divalent inorganic cation homeostasisGO:00725071650.018
spermatogenesisGO:0007283990.018
purine ribonucleoside metabolic processGO:00461281680.018
chemical homeostasisGO:00488782920.018
regulation of secretionGO:00510462240.018
cellular homeostasisGO:00197252520.018
organic substance catabolic processGO:19015753160.018
positive regulation of apoptotic processGO:00430651540.018
nitrogen compound transportGO:00717052290.018
cytoskeleton organizationGO:00070101110.017
negative regulation of wound healingGO:006104580.017
liver morphogenesisGO:007257630.017
positive regulation of secretion by cellGO:19035321280.017
nucleobase containing small molecule metabolic processGO:00550863160.017
response to nutrientGO:00075842480.017
positive regulation of gene expressionGO:00106282440.017
cell cell signalingGO:00072673350.017
cell type specific apoptotic processGO:00972851340.017
ion transmembrane transportGO:00342203650.017
response to monosaccharideGO:00342841590.017
heart morphogenesisGO:000300730.017
signal releaseGO:00230611450.017
ion homeostasisGO:00508012120.017
regulation of neuron differentiationGO:00456642080.017
calcium ion homeostasisGO:00550741620.017
negative regulation of cell differentiationGO:0045596990.017
negative regulation of metabolic processGO:00098923310.016
aromatic compound catabolic processGO:00194391680.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
inorganic ion transmembrane transportGO:00986602290.016
regulation of nervous system developmentGO:00519602640.016
nucleoside phosphate metabolic processGO:00067532830.016
developmental growthGO:00485891000.016
rna metabolic processGO:00160704060.016
development of primary sexual characteristicsGO:00451371070.016
cellular nitrogen compound catabolic processGO:00442701630.016
multi organism reproductive processGO:00447032620.016
cellular protein complex assemblyGO:0043623440.016
response to tumor necrosis factorGO:0034612560.016
wound healingGO:00420601220.016
proteolysisGO:00065081750.016
regulation of molecular functionGO:00650093980.016
ras protein signal transductionGO:0007265290.016
regulation of intracellular signal transductionGO:19025312180.016
regulation of fibrinolysisGO:005191720.016
coenzyme metabolic processGO:0006732860.015
negative regulation of canonical wnt signaling pathwayGO:009009040.015
regenerationGO:00310991630.015
regulation of cell projection organizationGO:00313441750.015
regulation of canonical wnt signaling pathwayGO:006082840.015
gamete generationGO:00072761240.015
regulation of cell adhesionGO:0030155520.015
gastrulationGO:000736920.015
positive regulation of programmed cell deathGO:00430681570.015
regulation of protein metabolic processGO:00512462890.015
cellular ion homeostasisGO:00068731840.015
purine containing compound metabolic processGO:00725212530.014
nucleoside phosphate catabolic processGO:19012921400.014
positive regulation of nervous system developmentGO:00519621780.014
negative regulation of multicellular organismal processGO:00512412030.014
amide transportGO:00428861050.014
regulation of cell growthGO:0001558850.014
nucleotide metabolic processGO:00091172790.014
lipid biosynthetic processGO:00086101280.014
alcohol metabolic processGO:0006066770.014
positive regulation of ion transportGO:0043270940.014
negative regulation of response to stimulusGO:00485851550.014
carboxylic acid biosynthetic processGO:0046394830.014
ribonucleoside catabolic processGO:00424541260.014
positive regulation of blood coagulationGO:003019440.014
embryonic appendage morphogenesisGO:003511340.014
acetyl coa metabolic processGO:0006084170.014
regulation of cell differentiationGO:00455953200.013
response to insulinGO:00328681330.013
cardiac muscle tissue morphogenesisGO:005500810.013
establishment of tissue polarityGO:000716420.013
regulation of neurogenesisGO:00507672470.013
peptide transportGO:0015833970.013
smooth muscle contractionGO:0006939370.013
protein localizationGO:00081041910.013
coagulationGO:0050817280.013
male gamete generationGO:0048232990.013
single organism organelle organizationGO:19025891800.013
action potentialGO:0001508540.013
digestionGO:0007586260.013
axis specificationGO:000979840.013
sodium ion transmembrane transportGO:0035725670.013
inflammatory responseGO:00069541500.013
cell motilityGO:00488702020.013
negative regulation of cellular metabolic processGO:00313242810.013
cell part morphogenesisGO:00329901230.013
fractalkine metabolic processGO:005075630.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
cellular response to low density lipoprotein particle stimulusGO:007140430.013
cell morphogenesis involved in neuron differentiationGO:00486671060.013
cellular response to lipidGO:00713962010.012
cardiovascular system developmentGO:00723581340.012
amine metabolic processGO:0009308380.012
ribonucleoside metabolic processGO:00091191740.012
organic hydroxy compound metabolic processGO:19016151150.012
ovulation cycleGO:0042698670.012
negative regulation of macromolecule metabolic processGO:00106052600.012
positive regulation of developmental processGO:00510942830.012
localization of cellGO:00516742020.012
cellular response to abiotic stimulusGO:0071214850.012
chromosome segregationGO:000705920.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
regulation of ion transportGO:00432692450.012
positive regulation of cell deathGO:00109421840.012
organ regenerationGO:00311001010.012
ribonucleotide catabolic processGO:00092611360.012
regulation of cellular protein metabolic processGO:00322682670.012
cellular response to peptide hormone stimulusGO:00713751200.012
response to lipopolysaccharideGO:00324961910.012
epithelial cell proliferation involved in liver morphogenesisGO:007257530.012
regulation of nucleotide metabolic processGO:00061401170.012
gonad developmentGO:00084061040.012
positive regulation of phosphorylationGO:00423271770.012
regulation of peptide secretionGO:0002791820.012
regulation of cellular localizationGO:00603412630.012
cellular response to oxygen levelsGO:0071453600.012
response to ethanolGO:00454711620.012
regulation of homotypic cell cell adhesionGO:003411040.012
regulation of growthGO:00400081050.012
blood coagulationGO:0007596260.012
response to bacteriumGO:00096172000.012
ribonucleotide metabolic processGO:00092592310.012
metal ion homeostasisGO:00550651860.012
hepatocyte differentiationGO:007036580.012
purine nucleotide catabolic processGO:00061951360.012
regulation of rna biosynthetic processGO:20011413810.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
regulation of hormone secretionGO:00468831060.012
nucleoside metabolic processGO:00091161790.012
small gtpase mediated signal transductionGO:0007264360.012
cellular calcium ion homeostasisGO:00068741600.011
transcription dna templatedGO:00063513770.011
circulatory system developmentGO:00723591340.011
organophosphate biosynthetic processGO:00904071430.011
purine ribonucleotide catabolic processGO:00091541360.011
limb morphogenesisGO:003510840.011
response to fatty acidGO:0070542650.011
regulation of signal transductionGO:00099663180.011
response to hexoseGO:00097461440.011
purine nucleoside catabolic processGO:00061521240.011
regulation of muscle system processGO:0090257790.011
cellular response to oxygen containing compoundGO:19017013860.011
meiotic cell cycle processGO:190304630.011
regulation of muscle contractionGO:0006937530.011
heart processGO:0003015570.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
hormone metabolic processGO:0042445690.011
carbohydrate derivative metabolic processGO:19011353460.011
positive regulation of transferase activityGO:0051347810.011
response to ketoneGO:19016541820.011
nucleoside catabolic processGO:00091641260.011
negative regulation of fibrinolysisGO:005191820.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
reactive oxygen species metabolic processGO:0072593370.011
cellular amine metabolic processGO:0044106380.011
cellular catabolic processGO:00442482950.011
cellular macromolecular complex assemblyGO:0034622580.011
response to growth factorGO:00708481890.011
heterocycle catabolic processGO:00467001670.011
response to other organismGO:00517072200.011
positive regulation of rna metabolic processGO:00512542030.011
hemostasisGO:0007599260.011
dicarboxylic acid metabolic processGO:0043648420.011
cellular cation homeostasisGO:00300031800.011
respiratory system developmentGO:0060541450.011
actin cytoskeleton organizationGO:0030036730.011
positive regulation of renin secretion into blood streamGO:190013510.011
positive regulation of protein phosphorylationGO:00019341350.011
response to cytokineGO:00340972150.010
regulation of behaviorGO:0050795610.010
positive regulation of nitrogen compound metabolic processGO:00511733340.010
potassium ion transmembrane transportGO:0071805710.010
response to glucoseGO:00097491360.010
carbohydrate metabolic processGO:00059751300.010
axon developmentGO:0061564960.010
positive regulation of kinase activityGO:0033674770.010
locomotionGO:00400112370.010
single organism catabolic processGO:00447122830.010
regulation of protein kinase activityGO:00458591050.010
positive regulation of cell developmentGO:00107201760.010
small molecule biosynthetic processGO:00442831240.010
mapk cascadeGO:00001651400.010
nucleotide catabolic processGO:00091661390.010
positive regulation of peptide hormone secretionGO:0090277500.010
rho protein signal transductionGO:0007266110.010
peptide hormone secretionGO:0030072840.010

Spink8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.036
disease of anatomical entityDOID:700.036
muscular diseaseDOID:008000000.015
nervous system diseaseDOID:86300.015
cardiovascular system diseaseDOID:128700.014
myopathyDOID:42300.013
muscle tissue diseaseDOID:6600.013
intrinsic cardiomyopathyDOID:006003600.013
cardiomyopathyDOID:005070000.013
heart diseaseDOID:11400.013
central nervous system diseaseDOID:33100.011
disease of metabolismDOID:001466700.011