Rattus norvegicus

4 known processes

Spink4

serine peptidase inhibitor, Kazal type 4

(Aliases: PEC-60)

Spink4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure morphogenesisGO:00096532980.082
cellular homeostasisGO:00197252520.073
intracellular signal transductionGO:00355563140.068
cellular chemical homeostasisGO:00550822470.055
metal ion transportGO:00300012890.051
neuron differentiationGO:00301823680.051
cell projection organizationGO:00300303020.050
regulation of multicellular organismal developmentGO:20000263760.049
regulation of cellular ketone metabolic processGO:0010565270.048
response to other organismGO:00517072200.047
cellular ketone metabolic processGO:0042180510.047
amine metabolic processGO:0009308380.046
regulation of nervous system developmentGO:00519602640.046
secretion by cellGO:00329402480.044
response to metal ionGO:00100382530.044
signal transduction by phosphorylationGO:00230141440.043
regulation of cell developmentGO:00602842630.043
cellular response to oxygen containing compoundGO:19017013860.042
secretionGO:00469033070.042
tissue developmentGO:00098882520.041
positive regulation of nucleobase containing compound metabolic processGO:00459353190.041
cellular metal ion homeostasisGO:00068751720.040
multicellular organismal signalingGO:0035637440.040
positive regulation of signalingGO:00230562700.040
cellular component biogenesisGO:00440853680.039
regulation of phosphorus metabolic processGO:00511743490.039
negative regulation of cell deathGO:00605482290.038
oxoacid metabolic processGO:00434362900.038
cellular amine metabolic processGO:0044106380.037
regulation of transcription dna templatedGO:00063553740.037
negative regulation of metabolic processGO:00098923310.036
response to inorganic substanceGO:00100353770.036
transcription from rna polymerase ii promoterGO:00063662520.036
homeostatic processGO:00425923310.035
positive regulation of secretion by cellGO:19035321280.035
transcription dna templatedGO:00063513770.034
programmed cell deathGO:00125013920.034
positive regulation of cell communicationGO:00106472710.034
cation transportGO:00068123820.034
positive regulation of nucleic acid templated transcriptionGO:19035081970.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
negative regulation of multicellular organismal processGO:00512412030.033
response to biotic stimulusGO:00096072260.032
positive regulation of cellular biosynthetic processGO:00313282950.032
carboxylic acid metabolic processGO:00197522890.032
regulation of cellular component organizationGO:00511283680.032
regulation of cellular amino acid metabolic processGO:000652120.032
regulation of cellular amine metabolic processGO:003323880.032
regulation of protein phosphorylationGO:00019321830.031
neuron projection developmentGO:00311752730.031
positive regulation of multicellular organismal processGO:00512403870.031
nucleic acid templated transcriptionGO:00976593790.031
macromolecule localizationGO:00330362520.031
positive regulation of phosphorylationGO:00423271770.031
positive regulation of gene expressionGO:00106282440.030
cellular component assemblyGO:00226073600.030
neurological system processGO:00508772190.029
regulation of protein metabolic processGO:00512462890.029
cellular divalent inorganic cation homeostasisGO:00725031620.029
regulation of nucleic acid templated transcriptionGO:19035063800.029
chemical homeostasisGO:00488782920.029
response to woundingGO:00096112540.028
purine nucleotide metabolic processGO:00061632290.028
response to extracellular stimulusGO:00099913800.028
locomotionGO:00400112370.028
regulation of catalytic activityGO:00507903040.027
mapk cascadeGO:00001651400.027
negative regulation of transportGO:00510511360.027
positive regulation of neurogenesisGO:00507691650.027
positive regulation of nervous system developmentGO:00519621780.027
response to external biotic stimulusGO:00432072210.026
regulation of cell differentiationGO:00455953200.026
organophosphate metabolic processGO:00196373700.026
calcium ion homeostasisGO:00550741620.026
regulation of molecular functionGO:00650093980.025
positive regulation of transcription dna templatedGO:00458931970.025
regulation of neuron differentiationGO:00456642080.025
positive regulation of cellular amine metabolic processGO:003324030.025
purine nucleotide catabolic processGO:00061951360.025
negative regulation of gene expressionGO:00106291990.025
response to acid chemicalGO:00011012220.025
cellular cation homeostasisGO:00300031800.024
negative regulation of cellular metabolic processGO:00313242810.024
protein phosphorylationGO:00064683450.024
cellular ion homeostasisGO:00068731840.024
eye morphogenesisGO:004859240.024
regulation of ion transportGO:00432692450.024
negative regulation of macromolecule metabolic processGO:00106052600.024
positive regulation of developmental processGO:00510942830.024
blood circulationGO:00080151830.023
positive regulation of phosphorus metabolic processGO:00105622620.023
ras protein signal transductionGO:0007265290.023
rna metabolic processGO:00160704060.023
regulation of intracellular signal transductionGO:19025312180.023
regulation of cellular localizationGO:00603412630.023
purine ribonucleoside metabolic processGO:00461281680.023
regulation of phosphate metabolic processGO:00192203490.023
organic acid metabolic processGO:00060822920.023
organic cyclic compound catabolic processGO:19013611750.023
calcium ion transportGO:00068161310.023
intracellular transportGO:00469071850.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
divalent inorganic cation homeostasisGO:00725071650.022
positive regulation of rna metabolic processGO:00512542030.022
organelle organizationGO:00069962660.021
cellular calcium ion homeostasisGO:00068741600.021
regulation of signal transductionGO:00099663180.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
cation homeostasisGO:00550801950.021
cellular component movementGO:00069282480.020
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.020
regulation of hormone secretionGO:00468831060.020
response to bacteriumGO:00096172000.020
regulation of neurogenesisGO:00507672470.020
cellular catabolic processGO:00442482950.020
regulation of protein modification processGO:00313991940.020
metal ion homeostasisGO:00550651860.020
divalent inorganic cation transportGO:00725111340.020
response to lipopolysaccharideGO:00324961910.020
purine ribonucleoside triphosphate metabolic processGO:00092051400.020
positive regulation of cellular component organizationGO:00511302000.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.020
regulation of blood vessel sizeGO:0050880890.020
positive regulation of molecular functionGO:00440932300.020
regulation of apoptotic processGO:00429813350.020
protein complex subunit organizationGO:00718223020.019
multi organism reproductive processGO:00447032620.019
ribonucleotide metabolic processGO:00092592310.019
sensory organ developmentGO:0007423740.019
cytosolic calcium ion homeostasisGO:00514801400.019
cellular amino acid metabolic processGO:00065201070.019
positive regulation of rna biosynthetic processGO:19026801970.019
neuron developmentGO:00486662860.019
positive regulation of cell proliferationGO:00082842490.019
multicellular organismal reproductive processGO:00486092330.019
regulation of secretion by cellGO:19035302080.019
regulation of transferase activityGO:00513381230.019
cellular response to acid chemicalGO:0071229750.019
ribonucleotide catabolic processGO:00092611360.019
positive regulation of response to stimulusGO:00485842850.018
response to growth factorGO:00708481890.018
positive regulation of cell developmentGO:00107201760.018
regulation of secretionGO:00510462240.018
apoptotic processGO:00069153810.018
cell growthGO:00160491040.018
nucleobase containing small molecule metabolic processGO:00550863160.018
nucleoside phosphate metabolic processGO:00067532830.018
reproductive processGO:00224143720.018
purine containing compound metabolic processGO:00725212530.018
purine ribonucleotide metabolic processGO:00091502270.018
positive regulation of phosphate metabolic processGO:00459372620.018
protein localizationGO:00081041910.018
growthGO:00400071650.018
regulation of rna biosynthetic processGO:20011413810.017
positive regulation of cellular component movementGO:00512721020.017
carbohydrate derivative catabolic processGO:19011361470.017
peptide hormone secretionGO:0030072840.017
nitrogen compound transportGO:00717052290.017
regulation of rna metabolic processGO:00512523910.017
regulation of cell proliferationGO:00421273590.017
regulation of system processGO:00440572080.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
positive regulation of biosynthetic processGO:00098913190.017
cell cell signalingGO:00072673350.017
positive regulation of cellular protein metabolic processGO:00322701670.017
regulation of metal ion transportGO:00109591180.017
single organism catabolic processGO:00447122830.016
response to nutrientGO:00075842480.016
organonitrogen compound biosynthetic processGO:19015661670.016
negative regulation of secretionGO:0051048820.016
regulation of neuron projection developmentGO:00109751610.016
nucleotide catabolic processGO:00091661390.016
cytoplasmic transportGO:00164821150.016
positive regulation of locomotionGO:00400171020.016
positive regulation of cell differentiationGO:00455972170.016
brain developmentGO:00074202470.016
negative regulation of cell differentiationGO:0045596990.016
ribose phosphate metabolic processGO:00196932350.016
cellular response to growth factor stimulusGO:00713631620.016
response to glucocorticoidGO:00513842230.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
negative regulation of cell communicationGO:00106481580.015
negative regulation of programmed cell deathGO:00430691830.015
cellular response to stressGO:00335542690.015
nucleoside metabolic processGO:00091161790.015
single organism intracellular transportGO:19025821660.015
protein transportGO:00150311320.015
purine ribonucleotide catabolic processGO:00091541360.015
lipid metabolic processGO:00066292830.015
negative regulation of signalingGO:00230571570.015
negative regulation of cellular biosynthetic processGO:00313271610.015
ion homeostasisGO:00508012120.015
negative regulation of biosynthetic processGO:00098901680.015
small gtpase mediated signal transductionGO:0007264360.015
glycosyl compound metabolic processGO:19016571820.015
single organism reproductive processGO:00447022970.015
rna biosynthetic processGO:00327743800.015
negative regulation of catalytic activityGO:00430861030.015
nucleoside triphosphate catabolic processGO:00091431230.014
central nervous system developmentGO:00074173110.014
nucleoside phosphate catabolic processGO:19012921400.014
organophosphate catabolic processGO:00464341480.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
response to glucoseGO:00097491360.014
localization of cellGO:00516742020.014
transmission of nerve impulseGO:0019226420.014
nucleobase containing compound catabolic processGO:00346551520.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
negative regulation of molecular functionGO:00440921330.014
regulation of anatomical structure sizeGO:00900661350.014
cellular lipid metabolic processGO:00442552080.013
transmembrane transportGO:00550854120.013
carbohydrate derivative metabolic processGO:19011353460.013
divalent metal ion transportGO:00708381320.013
catabolic processGO:00090563510.013
regulation of cell migrationGO:00303341280.013
regulation of response to stressGO:00801341260.013
positive regulation of protein phosphorylationGO:00019341350.013
organ morphogenesisGO:0009887750.013
positive regulation of intracellular signal transductionGO:19025331380.013
defense responseGO:00069521940.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
response to molecule of bacterial originGO:00022371940.013
peptide transportGO:0015833970.013
nucleotide metabolic processGO:00091172790.013
circulatory system processGO:00030131830.013
heterocycle catabolic processGO:00467001670.013
response to vitaminGO:00332731310.013
cellular response to endogenous stimulusGO:00714953770.013
regulation of homeostatic processGO:00328441010.013
organophosphate biosynthetic processGO:00904071430.013
gliogenesisGO:0042063930.013
regenerationGO:00310991630.013
organonitrogen compound catabolic processGO:19015651790.013
macromolecular complex subunit organizationGO:00439333390.012
single organism organelle organizationGO:19025891800.012
protein complex biogenesisGO:00702712630.012
reactive oxygen species biosynthetic processGO:190340980.012
positive regulation of signal transductionGO:00099671750.012
ribonucleoside metabolic processGO:00091191740.012
single organism behaviorGO:00447081300.012
chemosensory behaviorGO:000763520.012
amide transportGO:00428861050.012
gastrulationGO:000736920.012
purine ribonucleoside catabolic processGO:00461301240.012
glial cell differentiationGO:0010001650.012
ribonucleoside catabolic processGO:00424541260.012
negative regulation of cell proliferationGO:00082851190.012
response to oxidative stressGO:00069791860.012
neuronal action potentialGO:0019228350.012
spermatogenesisGO:0007283990.012
regulation of cell motilityGO:20001451310.012
cellular component morphogenesisGO:00329891550.012
regulation of mapk cascadeGO:00434081160.012
positive regulation of secretionGO:00510471400.012
regulation of cellular component movementGO:00512701500.012
positive regulation of neuron differentiationGO:00456661260.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
purine nucleoside catabolic processGO:00061521240.011
regulation of calcium ion transportGO:0051924770.011
positive regulation of ion transportGO:0043270940.011
gamete generationGO:00072761240.011
regulation of phosphorylationGO:00423252480.011
cell motilityGO:00488702020.011
regulation of behaviorGO:0050795610.011
carbohydrate derivative biosynthetic processGO:19011371240.011
cell part morphogenesisGO:00329901230.011
response to purine containing compoundGO:00140741260.011
purine nucleoside metabolic processGO:00422781690.011
response to ethanolGO:00454711620.011
regulation of membrane potentialGO:00423911100.011
response to decreased oxygen levelsGO:00362932370.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
axis specificationGO:000979840.011
axon developmentGO:0061564960.011
regulation of insulin secretionGO:0050796650.011
reactive oxygen species metabolic processGO:0072593370.011
regulation of response to woundingGO:1903034690.011
regulation of programmed cell deathGO:00430673410.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
regulation of locomotionGO:00400121480.011
regulation of canonical wnt signaling pathwayGO:006082840.011
multicellular organism growthGO:003526410.011
nucleoside catabolic processGO:00091641260.011
peptide secretionGO:0002790860.011
muscle system processGO:00030121150.011
cellular nitrogen compound catabolic processGO:00442701630.011
regulation of response to external stimulusGO:00321011060.011
embryonic pattern specificationGO:000988010.011
purine containing compound catabolic processGO:00725231380.011
glycosyl compound catabolic processGO:19016581260.011
regulation of kinase activityGO:00435491170.011
peptidyl amino acid modificationGO:00181931260.011
vascular process in circulatory systemGO:0003018960.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
retina morphogenesis in camera type eyeGO:006004210.011
negative regulation of cellular protein metabolic processGO:00322691060.011
cell cell signaling involved in cell fate commitmentGO:004516820.010
guanosine containing compound catabolic processGO:1901069710.010
hematopoietic progenitor cell differentiationGO:000224420.010
macromolecular complex assemblyGO:00650032730.010
regulation of hydrolase activityGO:00513361430.010
guanosine containing compound metabolic processGO:1901068740.010
multicellular organism reproductionGO:00325042330.010
cell morphogenesis involved in differentiationGO:00009041190.010
response to cytokineGO:00340972150.010
positive regulation of catalytic activityGO:00430851840.010
monovalent inorganic cation transportGO:00156721720.010
dna metabolic processGO:0006259960.010
response to ketoneGO:19016541820.010
negative regulation of apoptotic processGO:00430661810.010
negative regulation of transcription dna templatedGO:00458921160.010
camera type eye developmentGO:0043010480.010
regulation of cell projection organizationGO:00313441750.010
positive regulation of mapk cascadeGO:0043410920.010
agingGO:00075682410.010
epithelium developmentGO:0060429960.010
rho protein signal transductionGO:0007266110.010

Spink4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
sensory system diseaseDOID:005015500.012
disease of metabolismDOID:001466700.010