Rattus norvegicus

147 known processes

Pak3

p21 protein (Cdc42/Rac)-activated kinase 3

(Aliases: beta-PAK)

Pak3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecular complex assemblyGO:00650032730.338
Human Yeast
cellular response to endogenous stimulusGO:00714953770.302
Rat
cation transportGO:00068123820.248
regulation of cellular component organizationGO:00511283680.221
response to inorganic substanceGO:00100353770.189
anatomical structure morphogenesisGO:00096532980.179
reproductive processGO:00224143720.171
Yeast Worm
metal ion transportGO:00300012890.160
regulation of multicellular organismal developmentGO:20000263760.150
neuron developmentGO:00486662860.144
cell morphogenesisGO:00009021420.142
cellular response to peptide hormone stimulusGO:00713751200.134
Rat
regulation of membrane potentialGO:00423911100.133
neuron differentiationGO:00301823680.131
neuron projection developmentGO:00311752730.124
ion transmembrane transportGO:00342203650.124
cell cell signalingGO:00072673350.119
regulation of cell differentiationGO:00455953200.114
intracellular signal transductionGO:00355563140.113
Human Yeast
transmembrane transportGO:00550854120.113
Yeast
carboxylic acid metabolic processGO:00197522890.107
rna metabolic processGO:00160704060.105
organic acid metabolic processGO:00060822920.103
regulation of neurogenesisGO:00507672470.103
macromolecule localizationGO:00330362520.103
Yeast
cellular macromolecule localizationGO:00707271220.101
Yeast
cellular response to cytokine stimulusGO:00713451270.100
apoptotic processGO:00069153810.099
behaviorGO:00076102050.098
cellular response to organonitrogen compoundGO:00714171970.097
Rat
neurological system processGO:00508772190.096
regulation of cellular localizationGO:00603412630.095
Yeast
response to metal ionGO:00100382530.095
response to nutrient levelsGO:00316673700.093
cellular component movementGO:00069282480.091
Worm
secretion by cellGO:00329402480.089
positive regulation of locomotionGO:00400171020.089
positive regulation of nervous system developmentGO:00519621780.089
regulation of transcription dna templatedGO:00063553740.088
reproductionGO:00000032450.088
Yeast
rna biosynthetic processGO:00327743800.086
response to cytokineGO:00340972150.086
cellular response to hormone stimulusGO:00328702470.084
Rat
cell migrationGO:00164771970.082
Worm
negative regulation of nitrogen compound metabolic processGO:00511721610.081
regulation of neuron projection developmentGO:00109751610.080
lipid metabolic processGO:00066292830.078
synaptic growth at neuromuscular junctionGO:005112410.078
protein heterooligomerizationGO:0051291890.078
cellular component biogenesisGO:00440853680.077
Human Yeast Worm
growthGO:00400071650.076
Yeast
regulation of cell developmentGO:00602842630.075
regulation of system processGO:00440572080.075
cellular response to organic cyclic compoundGO:00714072020.074
cell projection organizationGO:00300303020.073
regulation of rna metabolic processGO:00512523910.072
positive regulation of signalingGO:00230562700.072
Human Yeast
organ morphogenesisGO:0009887750.072
Worm
protein complex assemblyGO:00064612630.071
Human
positive regulation of developmental processGO:00510942830.070
response to peptideGO:19016522920.069
Rat
regulation of hormone levelsGO:00108171870.068
transcription dna templatedGO:00063513770.067
regulation of neuron differentiationGO:00456642080.067
cell morphogenesis involved in differentiationGO:00009041190.066
central nervous system developmentGO:00074173110.066
protein transportGO:00150311320.065
Yeast
positive regulation of multicellular organismal processGO:00512403870.065
cell motilityGO:00488702020.065
Worm
programmed cell deathGO:00125013920.062
response to extracellular stimulusGO:00099913800.062
establishment of protein localizationGO:00451841410.062
Yeast
oxoacid metabolic processGO:00434362900.060
macromolecular complex subunit organizationGO:00439333390.060
Human Yeast
cellular lipid metabolic processGO:00442552080.059
carboxylic acid transportGO:00469421150.057
single organism biosynthetic processGO:00447113420.057
negative regulation of cellular metabolic processGO:00313242810.056
regulation of cell proliferationGO:00421273590.055
cellular chemical homeostasisGO:00550822470.053
cell communication involved in cardiac conductionGO:008606520.051
regulation of cell morphogenesis involved in differentiationGO:0010769720.050
regulation of nervous system developmentGO:00519602640.050
regulation of dendrite developmentGO:0050773590.050
positive regulation of neurogenesisGO:00507691650.050
secretionGO:00469033070.048
response to corticosteroidGO:00319602350.048
regulation of phosphate metabolic processGO:00192203490.048
Human Yeast
organophosphate metabolic processGO:00196373700.048
regulation of cell morphogenesisGO:0022604770.047
cellular response to stressGO:00335542690.047
Yeast
cell projection morphogenesisGO:00488581230.047
cellular response to insulin stimulusGO:0032869810.047
Rat
cellular amino acid metabolic processGO:00065201070.046
negative regulation of biosynthetic processGO:00098901680.045
nucleic acid templated transcriptionGO:00976593790.045
regulation of rna biosynthetic processGO:20011413810.045
cation homeostasisGO:00550801950.045
cell part morphogenesisGO:00329901230.044
regulation of intracellular signal transductionGO:19025312180.044
Human Yeast
positive regulation of response to stimulusGO:00485842850.044
Human Yeast
response to ketoneGO:19016541820.043
anion transportGO:00068201780.043
rhythmic processGO:00485111560.043
cellular component assemblyGO:00226073600.043
Human Yeast Worm
positive regulation of cell differentiationGO:00455972170.042
protein complex biogenesisGO:00702712630.042
Human
regulation of apoptotic processGO:00429813350.042
g protein coupled receptor signaling pathwayGO:00071862420.042
Yeast
neuron deathGO:00709971270.042
cellular ketone metabolic processGO:0042180510.041
regulation of cellular ketone metabolic processGO:0010565270.041
response to estrogenGO:00436272320.040
organelle organizationGO:00069962660.040
Human Yeast Rat
positive regulation of cell proliferationGO:00082842490.040
regulation of synaptic transmissionGO:00508041410.040
monocarboxylic acid metabolic processGO:00327871520.039
transmission of nerve impulseGO:0019226420.039
response to glucocorticoidGO:00513842230.039
single organism reproductive processGO:00447022970.039
Worm
neuron projection morphogenesisGO:00488121220.039
chemosensory behaviorGO:000763520.039
cellular response to nitrogen compoundGO:19016992100.039
Rat
hormone metabolic processGO:0042445690.039
axonogenesisGO:0007409710.039
Mouse
head developmentGO:00603222470.038
nitrogen compound transportGO:00717052290.038
regulation of nucleic acid templated transcriptionGO:19035063800.038
cellular component morphogenesisGO:00329891550.038
mechanoreceptor differentiationGO:004249020.038
positive regulation of synaptic vesicle transportGO:190280530.038
synapse organizationGO:0050808460.037
cellular amide metabolic processGO:0043603440.037
cell cycleGO:00070491010.037
Yeast
regulation of cell projection organizationGO:00313441750.036
regulation of cellular component biogenesisGO:0044087860.036
Human
action potentialGO:0001508540.036
response to acid chemicalGO:00011012220.036
response to decreased oxygen levelsGO:00362932370.036
Rat
response to molecule of bacterial originGO:00022371940.036
regulation of secretionGO:00510462240.036
positive regulation of phosphorus metabolic processGO:00105622620.036
Human Yeast
regulation of programmed cell deathGO:00430673410.035
positive regulation of cell communicationGO:00106472710.035
Human Yeast
axon developmentGO:0061564960.035
Mouse
regulation of locomotionGO:00400121480.035
chemical homeostasisGO:00488782920.035
positive regulation of neuron projection developmentGO:0010976990.035
locomotionGO:00400112370.034
Worm
hormone transportGO:00099141210.034
positive regulation of cell developmentGO:00107201760.034
multicellular organismal reproductive processGO:00486092330.034
cellular response to ketoneGO:1901655510.033
biological adhesionGO:00226101100.033
calcium mediated signaling using intracellular calcium sourceGO:003558410.033
cellular hormone metabolic processGO:0034754490.033
protein autophosphorylationGO:0046777660.033
Rat
adult locomotory behaviorGO:000834440.033
nucleobase containing small molecule metabolic processGO:00550863160.033
cellular response to oxygen containing compoundGO:19017013860.032
Rat
heart morphogenesisGO:000300730.032
membrane depolarization during cardiac muscle cell action potentialGO:008601210.032
intracellular transportGO:00469071850.032
Yeast
positive regulation of signal transductionGO:00099671750.032
Human Yeast
cellular protein localizationGO:00346131220.032
Yeast
positive regulation of neuron differentiationGO:00456661260.032
cellular homeostasisGO:00197252520.031
organic acid transportGO:00158491160.031
cellular response to corticosteroid stimulusGO:0071384690.031
single organism cellular localizationGO:19025801020.031
Yeast
cellular response to glucocorticoid stimulusGO:0071385680.031
acid secretionGO:0046717480.031
cell growthGO:00160491040.031
Yeast
protein complex subunit organizationGO:00718223020.031
Human
regulation of synaptic growth at neuromuscular junctionGO:000858210.031
single organism behaviorGO:00447081300.031
single organism intracellular transportGO:19025821660.030
Yeast
protein localizationGO:00081041910.030
Yeast
rhythmic synaptic transmissionGO:006002410.030
intracellular protein transportGO:0006886790.030
Yeast
cognitionGO:0050890920.030
vesicle mediated transportGO:00161921810.030
cell cycle processGO:0022402570.029
Yeast
regulation of blood circulationGO:19035221100.029
divalent inorganic cation homeostasisGO:00725071650.029
regulation of axonogenesisGO:0050770370.029
epithelium developmentGO:0060429960.029
cellular response to alcoholGO:0097306870.029
negative regulation of nucleobase containing compound metabolic processGO:00459341530.028
carbohydrate derivative metabolic processGO:19011353460.028
response to estradiolGO:00323551640.028
positive regulation of gene expressionGO:00106282440.028
regulation of molecular functionGO:00650093980.028
Human Yeast
blood circulationGO:00080151830.028
negative regulation of neuron differentiationGO:0045665620.028
amino acid transportGO:0006865700.028
multicellular organismal signalingGO:0035637440.027
inorganic cation transmembrane transportGO:00986622020.027
learning or memoryGO:0007611900.027
response to hypoxiaGO:00016662310.027
Rat
response to peptide hormoneGO:00434342780.027
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.026
localization of cellGO:00516742020.026
Worm
anterior posterior pattern specificationGO:000995210.026
regulation of cellular amine metabolic processGO:003323880.026
cellular divalent inorganic cation homeostasisGO:00725031620.026
response to transition metal nanoparticleGO:19902671220.026
neuronal action potentialGO:0019228350.025
regulation of phosphorus metabolic processGO:00511743490.025
Human Yeast
protein phosphorylationGO:00064683450.025
cellular response to steroid hormone stimulusGO:0071383930.025
dendrite developmentGO:0016358720.025
regulation of protein metabolic processGO:00512462890.025
Human Yeast
regulation of phosphorylationGO:00423252480.024
Human Yeast
cellular cation homeostasisGO:00300031800.024
sensory perceptionGO:00076001010.024
positive regulation of synaptic vesicle exocytosisGO:200030230.024
regulation of synapse structure and activityGO:0050803210.024
catabolic processGO:00090563510.024
response to insulinGO:00328681330.024
Rat
hair cell differentiationGO:003531520.024
forebrain developmentGO:0030900980.023
single organism membrane organizationGO:0044802740.023
transcription from rna polymerase ii promoterGO:00063662520.023
brain developmentGO:00074202470.023
developmental growth involved in morphogenesisGO:0060560330.023
negative regulation of response to stimulusGO:00485851550.022
positive regulation of protein modification processGO:00314011420.022
Human Yeast
cellular amine metabolic processGO:0044106380.022
negative regulation of multicellular organismal processGO:00512412030.022
ion homeostasisGO:00508012120.022
positive regulation of transportGO:00510502450.022
Yeast
response to axon injuryGO:0048678590.022
positive regulation of cell projection organizationGO:00313461110.022
positive regulation of ion transportGO:0043270940.022
response to histamineGO:003477630.022
somatic stem cell divisionGO:004810320.022
nucleotide metabolic processGO:00091172790.022
regulation of synaptic vesicle recyclingGO:190342110.022
positive regulation of cellular component organizationGO:00511302000.022
cellular ion homeostasisGO:00068731840.022
organic acid biosynthetic processGO:0016053830.022
organelle localizationGO:0051640550.022
regulation of synaptic vesicle endocytosisGO:190024210.022
multi organism reproductive processGO:00447032620.021
Yeast
response to bacteriumGO:00096172000.021
sensory organ developmentGO:0007423740.021
regulation of cellular amino acid metabolic processGO:000652120.021
regulation of ion transportGO:00432692450.021
cellular response to peptideGO:19016531330.021
Rat
response to growth factorGO:00708481890.021
peptidyl amino acid modificationGO:00181931260.021
Yeast
positive regulation of dendritic spine developmentGO:006099990.021
cardiac chamber developmentGO:000320510.021
anion transmembrane transportGO:0098656770.020
regulation of anatomical structure morphogenesisGO:00226031410.020
response to woundingGO:00096112540.020
neuron neuron synaptic transmissionGO:0007270600.020
negative regulation of programmed cell deathGO:00430691830.020
sexual reproductionGO:00199531480.020
Yeast
response to lipopolysaccharideGO:00324961910.020
single organism organelle organizationGO:19025891800.020
Human Yeast Rat
response to external biotic stimulusGO:00432072210.020
positive regulation of cellular biosynthetic processGO:00313282950.020
cell type specific apoptotic processGO:00972851340.020
amide transportGO:00428861050.020
gamete generationGO:00072761240.020
response to ethanolGO:00454711620.020
regulation of organic acid transportGO:0032890350.019
multicellular organism reproductionGO:00325042330.019
cytoplasmic transportGO:00164821150.019
Yeast
protein oligomerizationGO:00512591910.019
cellular metal ion homeostasisGO:00068751720.019
negative regulation of cellular component organizationGO:0051129830.019
mapk cascadeGO:00001651400.019
Human Yeast
regulation of cell cycleGO:0051726730.019
Yeast
cell morphogenesis involved in neuron differentiationGO:00486671060.019
negative regulation of cell communicationGO:00106481580.019
organonitrogen compound biosynthetic processGO:19015661670.019
response to interleukin 1GO:0070555550.019
response to oxygen levelsGO:00704822650.019
Rat
agingGO:00075682410.019
response to toxic substanceGO:00096361330.019
amine metabolic processGO:0009308380.019
positive regulation of cellular amino acid metabolic processGO:004576410.018
regulation of cell migrationGO:00303341280.018
mitotic cell cycle processGO:1903047350.018
Yeast
purine ribonucleotide metabolic processGO:00091502270.018
signal releaseGO:00230611450.018
positive regulation of cellular component movementGO:00512721020.018
neuron cell cell adhesionGO:000715830.018
developmental process involved in reproductionGO:00030061590.018
Worm
negative regulation of cell deathGO:00605482290.018
telencephalon developmentGO:0021537620.017
purine containing compound catabolic processGO:00725231380.017
response to biotic stimulusGO:00096072260.017
regulation of alternative mrna splicing via spliceosomeGO:000038120.017
divalent inorganic cation transportGO:00725111340.017
positive regulation of cellular amine metabolic processGO:003324030.017
ribose phosphate metabolic processGO:00196932350.017
limb morphogenesisGO:003510840.017
positive regulation of apoptotic processGO:00430651540.017
response to hydrogen peroxideGO:0042542890.017
regulation of protein localizationGO:0032880810.016
Yeast
fatty acid metabolic processGO:0006631990.016
peptide secretionGO:0002790860.016
tissue developmentGO:00098882520.016
regulation of cellular protein metabolic processGO:00322682670.016
Human Yeast
nucleoside phosphate metabolic processGO:00067532830.016
negative regulation of cellular biosynthetic processGO:00313271610.016
cellular response to external stimulusGO:00714961180.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.016
cardiovascular system developmentGO:00723581340.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
ventricular cardiac muscle cell action potentialGO:008600520.016
single organism catabolic processGO:00447122830.016
bmp signaling pathwayGO:003050940.015
regulation of hormone secretionGO:00468831060.015
cytosolic calcium ion homeostasisGO:00514801400.015
homeostatic processGO:00425923310.015
protein localization to membraneGO:0072657360.015
organic anion transportGO:00157111320.015
negative regulation of transportGO:00510511360.015
cellular calcium ion homeostasisGO:00068741600.015
ribonucleotide metabolic processGO:00092592310.015
response to reactive oxygen speciesGO:00003021200.015
olfactory learningGO:000835510.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
cellular response to lipidGO:00713962010.015
response to fatty acidGO:0070542650.015
negative regulation of cell proliferationGO:00082851190.015
synaptic vesicle endocytosisGO:004848840.015
negative regulation of nervous system developmentGO:0051961790.015
regulation of calcineurin nfat signaling cascadeGO:007088430.015
synaptic vesicle localizationGO:0097479240.015
negative regulation of developmental processGO:00510931250.015
olfactory behaviorGO:004204820.015
circulatory system processGO:00030131830.015
cellular response to growth factor stimulusGO:00713631620.015
synaptic transmissionGO:00072682350.015
axis specificationGO:000979840.015
response to other organismGO:00517072200.015
protein localization to organelleGO:0033365570.014
Yeast
establishment of vesicle localizationGO:0051650310.014
embryonic pattern specificationGO:000988010.014
positive regulation of molecular functionGO:00440932300.014
Human Yeast
protein tetramerizationGO:0051262380.014
calcium ion homeostasisGO:00550741620.014
developmental growthGO:00485891000.014
response to purine containing compoundGO:00140741260.014
metal ion homeostasisGO:00550651860.014
regulation of anion transportGO:0044070430.014
monovalent inorganic cation transportGO:00156721720.014
eye morphogenesisGO:004859240.014
negative regulation of gene expressionGO:00106291990.014
Yeast
organic substance catabolic processGO:19015753160.014
nucleoside phosphate biosynthetic processGO:19012931020.014
positive regulation of cell deathGO:00109421840.013
negative regulation of signalingGO:00230571570.013
salivary gland morphogenesisGO:000743510.013
locomotory exploration behaviorGO:003564110.013
negative regulation of cell differentiationGO:0045596990.013
positive regulation of transcription dna templatedGO:00458931970.013
gliogenesisGO:0042063930.013
dephosphorylationGO:0016311980.013
peptide transportGO:0015833970.013
regulation of cell motilityGO:20001451310.013
carbohydrate derivative biosynthetic processGO:19011371240.013
regulation of mrna splicing via spliceosomeGO:004802430.013
regulation of peptide hormone secretionGO:0090276800.013
synapse assemblyGO:0007416290.013
multi multicellular organism processGO:00447061380.013
establishment of protein localization to organelleGO:0072594440.013
Yeast
gap junction assemblyGO:001626420.013
inner ear receptor cell differentiationGO:006011320.013
regulation of secretion by cellGO:19035302080.013
tube developmentGO:0035295890.013
muscle tissue developmentGO:0060537580.013
neurotransmitter secretionGO:0007269330.013
cellular catabolic processGO:00442482950.013
regulation of synaptic plasticityGO:0048167700.013
steroid metabolic processGO:0008202730.013
peptidyl serine phosphorylationGO:0018105330.013
Yeast
positive regulation of phosphate metabolic processGO:00459372620.012
Human Yeast
cellular response to extracellular stimulusGO:0031668730.012
cardiac ventricle developmentGO:000323110.012
regulation of neuron deathGO:19012141150.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.012
regulation of catalytic activityGO:00507903040.012
Human Yeast
gland developmentGO:00487321550.012
inorganic ion transmembrane transportGO:00986602290.012
purine ribonucleoside metabolic processGO:00461281680.012
regulation of metal ion transportGO:00109591180.012
positive regulation of cell motilityGO:2000147970.012
inflammatory responseGO:00069541500.012
muscle structure developmentGO:0061061870.012
organic hydroxy compound metabolic processGO:19016151150.012
negative regulation of macromolecule metabolic processGO:00106052600.012
Yeast
axon guidanceGO:0007411240.012
cardiac conductionGO:006133720.012
detection of calcium ionGO:000551310.012
negative regulation of molecular functionGO:00440921330.012
protein localization to chromosome centromeric regionGO:007145910.012
regulation of respiratory gaseous exchange by neurological system processGO:000208710.012
protein homooligomerizationGO:0051260910.012
positive regulation of programmed cell deathGO:00430681570.012
hormone secretionGO:00468791150.012
neurotransmitter transportGO:0006836420.012
neuron projection extensionGO:1990138260.012
positive regulation of phosphorylationGO:00423271770.012
Human Yeast
purine containing compound metabolic processGO:00725212530.012
male gamete generationGO:0048232990.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
defense responseGO:00069521940.012
positive regulation of rna metabolic processGO:00512542030.011
protein targetingGO:0006605610.011
Yeast
regulation of canonical wnt signaling pathwayGO:006082840.011
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.011
regulation of protein phosphorylationGO:00019321830.011
Human Yeast
lipid modificationGO:0030258520.011
motor neuron axon guidanceGO:000804510.011
membrane organizationGO:0061024940.011
detection of visible lightGO:000958430.011
regulation of muscle system processGO:0090257790.011
purine nucleotide metabolic processGO:00061632290.011
axon ensheathmentGO:0008366400.011
small molecule catabolic processGO:0044282590.011
glutamate secretionGO:0014047190.011
response to radiationGO:00093141370.011
neuron fate commitmentGO:004866340.011
regulation of nucleotide metabolic processGO:00061401170.011
cellular response to histamineGO:007142030.011
cell cycle checkpointGO:000007520.011
response to vitaminGO:00332731310.011
response to nutrientGO:00075842480.011
regulation of growthGO:00400081050.011
positive regulation of protein metabolic processGO:00512471780.011
Human Yeast
asymmetric stem cell divisionGO:009872220.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
developmental maturationGO:0021700250.011
cellular response to oxidative stressGO:0034599760.011
auditory receptor cell differentiationGO:004249120.011
response to calcium ionGO:0051592590.011
cytokinetic processGO:003250610.011
Yeast
response to campGO:0051591910.011
nucleobase containing compound catabolic processGO:00346551520.011
activation of mapkkk activityGO:000018510.011
Yeast
cerebral cortex tangential migrationGO:002180010.011
peptidyl serine modificationGO:0018209340.011
Yeast
rna localizationGO:000640340.010
axon choice point recognitionGO:001619820.010
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.010
central nervous system neuron axonogenesisGO:002195510.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
negative regulation of apoptotic processGO:00430661810.010
positive regulation of cellular protein metabolic processGO:00322701670.010
Human Yeast
male sex differentiationGO:0046661640.010
dna metabolic processGO:0006259960.010
positive regulation of blood circulationGO:1903524650.010
response to activityGO:0014823730.010
muscle organ morphogenesisGO:004864410.010
stem cell divisionGO:001714540.010
regulation of homeostatic processGO:00328441010.010
endoplasmic reticulum organizationGO:000702910.010
neuromuscular processGO:005090520.010
positive regulation of rna biosynthetic processGO:19026801970.010
glucose homeostasisGO:0042593750.010
carboxylic acid biosynthetic processGO:0046394830.010

Pak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.034
cancerDOID:16200.034
disease of cellular proliferationDOID:1456600.034
substance dependenceDOID:997300.034
substance related disorderDOID:30300.034
disease of mental healthDOID:15000.034
Human
disease of anatomical entityDOID:700.013
musculoskeletal system diseaseDOID:1700.013
nervous system diseaseDOID:86300.011