IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Sub1

SUB1 homolog (S. cerevisiae)

(Aliases: Rpo2tc1,MGC109653)

Entrez: 192269
RGD: 621582
Ensembl: ENSRNOG00000011558
UniProtKB: Q63396

Process Predictions
Disease Predictions

Sub1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
regulation of nitric oxide synthase activity	GO:0050999	8	0.586
positive regulation of nitric oxide synthase activity	GO:0051000	5	0.480
positive regulation of oxidoreductase activity	GO:0051353	7	0.353
regulation of cyclase activity	GO:0031279	21	0.318
regulation of high voltage gated calcium channel activity	GO:1901841	3	0.316
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.303
regulation of adenylate cyclase activity	GO:0045761	18	0.282
response to glucocorticoid	GO:0051384	223	0.180
regulation of monooxygenase activity	GO:0032768	8	0.178
activation of adenylate cyclase activity	GO:0007190	7	0.149
regulation of secretion	GO:0051046	224	0.136
cell part morphogenesis	GO:0032990	123	0.135
regulation of camp biosynthetic process	GO:0030817	38	0.134
regulation of rna biosynthetic process	GO:2001141	381	0.122
regulation of purine nucleotide biosynthetic process	GO:1900371	46	0.117
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.115
ribonucleotide biosynthetic process	GO:0009260	85	0.114
cell morphogenesis involved in differentiation	GO:0000904	119	0.101
ribose phosphate metabolic process	GO:0019693	235	0.098
rna biosynthetic process	GO:0032774	380	0.097
regulation of calcium ion transmembrane transport	GO:1903169	18	0.094
regulation of ion transmembrane transporter activity	GO:0032412	48	0.093
regulation of ryanodine sensitive calcium release channel activity	GO:0060314	5	0.089
positive regulation of biosynthetic process	GO:0009891	319	0.088
cellular component biogenesis	GO:0044085	368	0.087
macromolecular complex assembly	GO:0065003	273	0.086
positive regulation of monooxygenase activity	GO:0032770	5	0.085
regulation of phosphorus metabolic process	GO:0051174	349	0.085
nucleoside phosphate metabolic process	GO:0006753	283	0.082
carbohydrate derivative metabolic process	GO:1901135	346	0.080
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	34	0.080
positive regulation of cyclase activity	GO:0031281	15	0.076
positive regulation of phosphate metabolic process	GO:0045937	262	0.074
regulation of cellular component organization	GO:0051128	368	0.073
purine nucleotide metabolic process	GO:0006163	229	0.073
rna metabolic process	GO:0016070	406	0.072
regulation of cellular localization	GO:0060341	263	0.071
positive regulation of response to stimulus	GO:0048584	285	0.070
cellular ketone metabolic process	GO:0042180	51	0.069
purine ribonucleotide metabolic process	GO:0009150	227	0.068
cyclic nucleotide biosynthetic process	GO:0009190	63	0.067
positive regulation of camp biosynthetic process	GO:0030819	28	0.067
cyclic nucleotide metabolic process	GO:0009187	80	0.064
regulation of nucleotide metabolic process	GO:0006140	117	0.064
divalent metal ion transport	GO:0070838	132	0.063
regulation of lyase activity	GO:0051339	22	0.061
regulation of molecular function	GO:0065009	398	0.061
developmental process involved in reproduction	GO:0003006	159	0.059
intracellular signal transduction	GO:0035556	314	0.059
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.058
response to ketone	GO:1901654	182	0.055
regulation of cellular amine metabolic process	GO:0033238	8	0.054
programmed cell death	GO:0012501	392	0.054
regulation of proteasomal protein catabolic process	GO:0061136	4	0.054
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.054
cellular amino acid metabolic process	GO:0006520	107	0.053
regulation of cyclic nucleotide metabolic process	GO:0030799	51	0.053
response to mineralocorticoid	GO:0051385	49	0.053
regulation of phosphate metabolic process	GO:0019220	349	0.053
positive regulation of multicellular organismal process	GO:0051240	387	0.053
protein complex subunit organization	GO:0071822	302	0.052
positive regulation of cellular amine metabolic process	GO:0033240	3	0.052
response to amphetamine	GO:0001975	25	0.051
single organism biosynthetic process	GO:0044711	342	0.050
response to peptide	GO:1901652	292	0.050
secretion	GO:0046903	307	0.050
regulation of calcium ion transmembrane transporter activity	GO:1901019	17	0.050
cellular component assembly	GO:0022607	360	0.050
reproduction	GO:0000003	245	0.050
homeostatic process	GO:0042592	331	0.049
regulation of rna metabolic process	GO:0051252	391	0.049
secretion by cell	GO:0032940	248	0.048
positive regulation of cellular biosynthetic process	GO:0031328	295	0.048
purine containing compound metabolic process	GO:0072521	253	0.048
synaptic growth at neuromuscular junction	GO:0051124	1	0.046
transcription dna templated	GO:0006351	377	0.046
protein complex biogenesis	GO:0070271	263	0.045
regulation of blood circulation	GO:1903522	110	0.044
peptidyl amino acid modification	GO:0018193	126	0.044
organic acid metabolic process	GO:0006082	292	0.044
purine nucleotide biosynthetic process	GO:0006164	83	0.044
neuron differentiation	GO:0030182	368	0.044
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.043
amine metabolic process	GO:0009308	38	0.043
regulation of nucleic acid templated transcription	GO:1903506	380	0.042
nucleotide metabolic process	GO:0009117	279	0.041
nucleoside phosphate biosynthetic process	GO:1901293	102	0.041
cell morphogenesis	GO:0000902	142	0.041
negative regulation of response to stimulus	GO:0048585	155	0.040
purine nucleoside metabolic process	GO:0042278	169	0.040
regulation of nucleotide biosynthetic process	GO:0030808	47	0.040
circulatory system process	GO:0003013	183	0.040
ribonucleotide metabolic process	GO:0009259	231	0.039
regulation of purine nucleotide metabolic process	GO:1900542	115	0.038
cellular response to hormone stimulus	GO:0032870	247	0.038
ribose phosphate biosynthetic process	GO:0046390	87	0.038
macromolecular complex subunit organization	GO:0043933	339	0.037
chemical homeostasis	GO:0048878	292	0.037
regulation of transporter activity	GO:0032409	50	0.037
nucleotide biosynthetic process	GO:0009165	98	0.036
positive regulation of lyase activity	GO:0051349	15	0.036
multicellular organismal reproductive process	GO:0048609	233	0.036
transmembrane transport	GO:0055085	412	0.036
camp metabolic process	GO:0046058	63	0.035
regulation of catalytic activity	GO:0050790	304	0.035
cytosolic calcium ion homeostasis	GO:0051480	140	0.035
positive regulation of cyclic nucleotide metabolic process	GO:0030801	37	0.035
response to peptide hormone	GO:0043434	278	0.035
neuron projection morphogenesis	GO:0048812	122	0.035
neuron development	GO:0048666	286	0.035
negative regulation of cellular metabolic process	GO:0031324	281	0.034
carbohydrate derivative biosynthetic process	GO:1901137	124	0.034
blood circulation	GO:0008015	183	0.034
positive regulation of molecular function	GO:0044093	230	0.034
calcium ion transmembrane transport	GO:0070588	70	0.033
regulation of transcription dna templated	GO:0006355	374	0.033
camp biosynthetic process	GO:0006171	47	0.033
response to corticosteroid	GO:0031960	235	0.033
cellular metal ion homeostasis	GO:0006875	172	0.033
cation transmembrane transport	GO:0098655	263	0.033
neuron projection development	GO:0031175	273	0.032
positive regulation of catalytic activity	GO:0043085	184	0.032
cellular response to peptide	GO:1901653	133	0.032
regulation of cation channel activity	GO:2001257	23	0.032
immune system process	GO:0002376	204	0.032
inorganic cation transmembrane transport	GO:0098662	202	0.032
cellular response to organonitrogen compound	GO:0071417	197	0.031
nucleic acid templated transcription	GO:0097659	379	0.031
organonitrogen compound biosynthetic process	GO:1901566	167	0.030
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.030
purine ribonucleoside metabolic process	GO:0046128	168	0.030
protein phosphorylation	GO:0006468	345	0.029
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.029
regulation of cellular ketone metabolic process	GO:0010565	27	0.029
protein oligomerization	GO:0051259	191	0.029
cellular amine metabolic process	GO:0044106	38	0.029
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.029
cellular response to insulin stimulus	GO:0032869	81	0.028
regulation of oxidoreductase activity	GO:0051341	11	0.028
positive regulation of protein modification process	GO:0031401	142	0.028
positive regulation of phosphorus metabolic process	GO:0010562	262	0.028
carboxylic acid metabolic process	GO:0019752	289	0.028
transcription from rna polymerase ii promoter	GO:0006366	252	0.027
divalent inorganic cation transport	GO:0072511	134	0.027
regulation of transmembrane transport	GO:0034762	122	0.027
cellular response to endogenous stimulus	GO:0071495	377	0.027
organic substance catabolic process	GO:1901575	316	0.027
cyclic purine nucleotide metabolic process	GO:0052652	62	0.027
response to hexose	GO:0009746	144	0.027
regulation of multicellular organismal development	GO:2000026	376	0.027
cation homeostasis	GO:0055080	195	0.027
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.027
protein complex assembly	GO:0006461	263	0.026
cation transport	GO:0006812	382	0.026
purine ribonucleotide biosynthetic process	GO:0009152	81	0.026
response to oxidative stress	GO:0006979	186	0.026
negative regulation of cell communication	GO:0010648	158	0.026
positive regulation of camp metabolic process	GO:0030816	31	0.026
regulation of voltage gated calcium channel activity	GO:1901385	6	0.026
regulation of protein metabolic process	GO:0051246	289	0.026
mitochondrion organization	GO:0007005	35	0.026
regulation of cellular amino acid metabolic process	GO:0006521	2	0.026
negative regulation of signaling	GO:0023057	157	0.025
response to monosaccharide	GO:0034284	159	0.025
purine containing compound biosynthetic process	GO:0072522	85	0.025
positive regulation of nucleotide metabolic process	GO:0045981	91	0.025
cellular response to nitrogen compound	GO:1901699	210	0.025
metal ion transport	GO:0030001	289	0.025
cellular response to peptide hormone stimulus	GO:0071375	120	0.024
regulation of protein localization	GO:0032880	81	0.024
regulation of metal ion transport	GO:0010959	118	0.024
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.024
cellular response to oxygen containing compound	GO:1901701	386	0.024
nucleobase containing small molecule metabolic process	GO:0055086	316	0.024
reproductive process	GO:0022414	372	0.023
cellular homeostasis	GO:0019725	252	0.023
positive regulation of adenylate cyclase activity	GO:0045762	12	0.023
cellular ion homeostasis	GO:0006873	184	0.023
catabolic process	GO:0009056	351	0.023
striated muscle contraction	GO:0006941	44	0.023
regulation of ion transmembrane transport	GO:0034765	121	0.023
regulation of ion transport	GO:0043269	245	0.023
neuron death	GO:0070997	127	0.022
tissue development	GO:0009888	252	0.022
neuron apoptotic process	GO:0051402	88	0.022
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.022
dendrite morphogenesis	GO:0048813	43	0.022
negative regulation of metabolic process	GO:0009892	331	0.021
positive regulation of transport	GO:0051050	245	0.021
regulation of secretion by cell	GO:1903530	208	0.021
negative regulation of transport	GO:0051051	136	0.021
ion homeostasis	GO:0050801	212	0.021
cell cell signaling	GO:0007267	335	0.021
regulation of phosphorylation	GO:0042325	248	0.021
muscle tissue development	GO:0060537	58	0.020
cell projection morphogenesis	GO:0048858	123	0.020
multi organism reproductive process	GO:0044703	262	0.020
muscle structure development	GO:0061061	87	0.020
regulation of muscle organ development	GO:0048634	26	0.020
small gtpase mediated signal transduction	GO:0007264	36	0.020
positive regulation of transcription dna templated	GO:0045893	197	0.020
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.020
positive regulation of cellular protein metabolic process	GO:0032270	167	0.019
central nervous system development	GO:0007417	311	0.019
regulation of homeostatic process	GO:0032844	101	0.019
negative regulation of macromolecule metabolic process	GO:0010605	260	0.019
lipid biosynthetic process	GO:0008610	128	0.019
calcium ion transport	GO:0006816	131	0.019
response to hypoxia	GO:0001666	231	0.019
adult locomotory behavior	GO:0008344	4	0.018
response to glucose	GO:0009749	136	0.018
negative regulation of signal transduction	GO:0009968	83	0.018
nucleoside metabolic process	GO:0009116	179	0.018
regulation of cell differentiation	GO:0045595	320	0.018
single organism reproductive process	GO:0044702	297	0.018
regulation of camp metabolic process	GO:0030814	43	0.018
regulation of cellular response to stress	GO:0080135	49	0.017
regulation of catabolic process	GO:0009894	113	0.017
second messenger mediated signaling	GO:0019932	51	0.017
regulation of neuron death	GO:1901214	115	0.017
aromatic compound catabolic process	GO:0019439	168	0.017
gamete generation	GO:0007276	124	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.017
regulation of transmembrane transporter activity	GO:0022898	49	0.016
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.016
regulation of calcium ion transport	GO:0051924	77	0.016
locomotion	GO:0040011	237	0.016
phosphatidylinositol dephosphorylation	GO:0046856	4	0.016
calcium mediated signaling	GO:0019722	23	0.016
multicellular organism reproduction	GO:0032504	233	0.016
regulation of cellular protein metabolic process	GO:0032268	267	0.016
hormone transport	GO:0009914	121	0.016
cellular component morphogenesis	GO:0032989	155	0.016
cellular lipid metabolic process	GO:0044255	208	0.016
positive regulation of intracellular signal transduction	GO:1902533	138	0.016
viral genome replication	GO:0019079	2	0.016
purine nucleoside catabolic process	GO:0006152	124	0.015
regulation of heart contraction	GO:0008016	48	0.015
negative regulation of cellular biosynthetic process	GO:0031327	161	0.015
cellular chemical homeostasis	GO:0055082	247	0.015
positive regulation of cellular component organization	GO:0051130	200	0.015
oxoacid metabolic process	GO:0043436	290	0.015
reproductive structure development	GO:0048608	128	0.015
apoptotic process	GO:0006915	381	0.015
inorganic ion transmembrane transport	GO:0098660	229	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.015
regulation of cell growth	GO:0001558	85	0.015
negative regulation of phosphorus metabolic process	GO:0010563	80	0.014
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	4	0.014
cellular nitrogen compound catabolic process	GO:0044270	163	0.014
organonitrogen compound catabolic process	GO:1901565	179	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.014
heterocycle catabolic process	GO:0046700	167	0.014
regulation of cellular catabolic process	GO:0031329	101	0.014
cell projection organization	GO:0030030	302	0.014
single organism organelle organization	GO:1902589	180	0.014
positive regulation of signaling	GO:0023056	270	0.014
regulation of system process	GO:0044057	208	0.014
organophosphate biosynthetic process	GO:0090407	143	0.014
regulation of cell development	GO:0060284	263	0.014
organic cyclic compound catabolic process	GO:1901361	175	0.014
dephosphorylation	GO:0016311	98	0.014
nucleoside phosphate catabolic process	GO:1901292	140	0.014
divalent inorganic cation homeostasis	GO:0072507	165	0.013
regulation of hydrolase activity	GO:0051336	143	0.013
mitotic spindle organization	GO:0007052	2	0.013
ion transmembrane transport	GO:0034220	365	0.013
positive regulation of secretion	GO:0051047	140	0.013
regulation of signal transduction	GO:0009966	318	0.013
metal ion homeostasis	GO:0055065	186	0.013
negative regulation of rna metabolic process	GO:0051253	123	0.013
response to extracellular stimulus	GO:0009991	380	0.013
response to insulin	GO:0032868	133	0.013
anatomical structure morphogenesis	GO:0009653	298	0.013
olfactory learning	GO:0008355	1	0.013
response to carbohydrate	GO:0009743	183	0.013
brain development	GO:0007420	247	0.013
ncrna processing	GO:0034470	3	0.013
organophosphate metabolic process	GO:0019637	370	0.012
positive regulation of developmental process	GO:0051094	283	0.012
cellular calcium ion homeostasis	GO:0006874	160	0.012
heart contraction	GO:0060047	57	0.012
positive regulation of blood circulation	GO:1903524	65	0.012
sensory perception of pain	GO:0019233	73	0.012
positive regulation of rna biosynthetic process	GO:1902680	197	0.012
behavior	GO:0007610	205	0.012
positive regulation of phosphorylation	GO:0042327	177	0.012
regulation of neuron apoptotic process	GO:0043523	83	0.012
regulation of viral genome replication	GO:0045069	2	0.012
development of primary sexual characteristics	GO:0045137	107	0.012
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.012
head development	GO:0060322	247	0.012
nucleobase containing compound catabolic process	GO:0034655	152	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.012
inflammatory response	GO:0006954	150	0.011
regulation of embryonic development	GO:0045995	2	0.011
regulation of muscle system process	GO:0090257	79	0.011
negative regulation of gene expression	GO:0010629	199	0.011
positive regulation of cell differentiation	GO:0045597	217	0.011
response to corticosterone	GO:0051412	40	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
synapse organization	GO:0050808	46	0.011
muscle cell differentiation	GO:0042692	52	0.011
regulation of striated muscle tissue development	GO:0016202	25	0.011
ribonucleoside metabolic process	GO:0009119	174	0.011
embryonic axis specification	GO:0000578	1	0.011
regulation of neuron differentiation	GO:0045664	208	0.011
gonad development	GO:0008406	104	0.011
positive regulation of apoptotic process	GO:0043065	154	0.011
cellular cation homeostasis	GO:0030003	180	0.011
developmental growth	GO:0048589	100	0.010
regulation of intracellular signal transduction	GO:1902531	218	0.010
muscle organ development	GO:0007517	50	0.010
neurological system process	GO:0050877	219	0.010
male gamete generation	GO:0048232	99	0.010
negative regulation of transcription dna templated	GO:0045892	116	0.010
regulation of programmed cell death	GO:0043067	341	0.010
skeletal muscle organ development	GO:0060538	33	0.010
striated muscle tissue development	GO:0014706	58	0.010
cellular response to organic cyclic compound	GO:0071407	202	0.010
regulation of organelle organization	GO:0033043	80	0.010
regulation of neurogenesis	GO:0050767	247	0.010
cell cycle	GO:0007049	101	0.010

Sub1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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