Rattus norvegicus

0 known processes

Sh2d4a

SH2 domain containing 4A

Sh2d4a biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular localizationGO:00603412630.107
positive regulation of transportGO:00510502450.107
regulation of nucleic acid templated transcriptionGO:19035063800.095
positive regulation of nitrogen compound metabolic processGO:00511733340.090
response to mineralocorticoidGO:0051385490.081
positive regulation of macromolecule biosynthetic processGO:00105572470.080
positive regulation of biosynthetic processGO:00098913190.077
wnt signaling pathway calcium modulating pathwayGO:000722310.070
regulation of rna metabolic processGO:00512523910.068
cellular metal ion homeostasisGO:00068751720.068
cation homeostasisGO:00550801950.068
macromolecule localizationGO:00330362520.068
regulation of ion transportGO:00432692450.067
cation transportGO:00068123820.064
cellular cation homeostasisGO:00300031800.064
secretion by cellGO:00329402480.061
positive regulation of cellular biosynthetic processGO:00313282950.059
regulation of cellular component organizationGO:00511283680.058
macromolecular complex subunit organizationGO:00439333390.056
nitrogen compound transportGO:00717052290.055
reproductive processGO:00224143720.055
positive regulation of rna metabolic processGO:00512542030.055
positive regulation of rna biosynthetic processGO:19026801970.052
positive regulation of nucleic acid templated transcriptionGO:19035081970.051
response to external biotic stimulusGO:00432072210.049
positive regulation of gene expressionGO:00106282440.047
response to peptide hormoneGO:00434342780.047
regulation of hormone levelsGO:00108171870.046
positive regulation of nucleobase containing compound metabolic processGO:00459353190.046
negative regulation of gene expressionGO:00106291990.045
transcription dna templatedGO:00063513770.044
metal ion transportGO:00300012890.044
regulation of transcription dna templatedGO:00063553740.043
regulation of stem cell differentiationGO:200073620.040
regulation of rna biosynthetic processGO:20011413810.040
hepaticobiliary system developmentGO:0061008900.040
response to bacteriumGO:00096172000.040
response to molecule of bacterial originGO:00022371940.040
oxoacid metabolic processGO:00434362900.039
tissue developmentGO:00098882520.038
cellular component assemblyGO:00226073600.038
gland developmentGO:00487321550.037
intracellular signal transductionGO:00355563140.037
cellular ion homeostasisGO:00068731840.037
response to metal ionGO:00100382530.037
transmembrane transportGO:00550854120.036
rna metabolic processGO:00160704060.036
nucleic acid templated transcriptionGO:00976593790.036
regulation of response to woundingGO:1903034690.035
amine metabolic processGO:0009308380.035
protein phosphorylationGO:00064683450.035
organic acid metabolic processGO:00060822920.035
negative regulation of macromolecule metabolic processGO:00106052600.035
negative regulation of metabolic processGO:00098923310.035
Human
nucleobase containing small molecule metabolic processGO:00550863160.034
cellular amino acid metabolic processGO:00065201070.034
cellular amine metabolic processGO:0044106380.032
response to estrogenGO:00436272320.032
calcium ion homeostasisGO:00550741620.031
rna biosynthetic processGO:00327743800.030
negative regulation of cellular metabolic processGO:00313242810.030
Human
response to nutrientGO:00075842480.030
negative regulation of cell communicationGO:00106481580.030
cellular homeostasisGO:00197252520.030
response to inorganic substanceGO:00100353770.029
negative regulation of multicellular organismal processGO:00512412030.029
negative regulation of nitrogen compound metabolic processGO:00511721610.029
regulation of cellular ketone metabolic processGO:0010565270.029
positive regulation of multicellular organismal processGO:00512403870.029
cellular divalent inorganic cation homeostasisGO:00725031620.028
regulation of catalytic activityGO:00507903040.027
Human
regulation of protein metabolic processGO:00512462890.027
negative regulation of response to stimulusGO:00485851550.027
negative regulation of macromolecule biosynthetic processGO:00105581480.027
circulatory system processGO:00030131830.026
response to oxidative stressGO:00069791860.026
lipid biosynthetic processGO:00086101280.026
regulation of phosphorus metabolic processGO:00511743490.026
Human
defense responseGO:00069521940.026
response to nutrient levelsGO:00316673700.026
regulation of programmed cell deathGO:00430673410.025
positive regulation of transcription dna templatedGO:00458931970.025
single organism intracellular transportGO:19025821660.025
regulation of cell developmentGO:00602842630.025
nucleotide metabolic processGO:00091172790.025
positive regulation of molecular functionGO:00440932300.025
regulation of molecular functionGO:00650093980.025
Human
gonad developmentGO:00084061040.024
carboxylic acid metabolic processGO:00197522890.024
cellular chemical homeostasisGO:00550822470.024
regulation of transcription from rna polymerase ii promoterGO:00063572340.024
protein localization to organelleGO:0033365570.024
response to hypoxiaGO:00016662310.024
organelle organizationGO:00069962660.023
positive regulation of developmental processGO:00510942830.023
regulation of cell proliferationGO:00421273590.023
head developmentGO:00603222470.023
epithelial cell proliferationGO:0050673540.023
cellular response to oxygen containing compoundGO:19017013860.023
ribonucleotide metabolic processGO:00092592310.023
central nervous system developmentGO:00074173110.023
female pregnancyGO:00075651220.023
divalent inorganic cation homeostasisGO:00725071650.023
transcription from rna polymerase ii promoterGO:00063662520.023
ion homeostasisGO:00508012120.023
calcium ion transportGO:00068161310.022
regulation of growthGO:00400081050.022
multi organism reproductive processGO:00447032620.021
positive regulation of programmed cell deathGO:00430681570.021
positive regulation of response to stimulusGO:00485842850.021
negative regulation of protein metabolic processGO:00512481140.021
negative regulation of biosynthetic processGO:00098901680.021
cellular response to endogenous stimulusGO:00714953770.021
metal ion homeostasisGO:00550651860.021
protein oligomerizationGO:00512591910.021
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
muscle contractionGO:0006936880.020
response to acid chemicalGO:00011012220.020
jak stat cascadeGO:0007259260.020
immune system processGO:00023762040.020
positive regulation of cell developmentGO:00107201760.020
multi multicellular organism processGO:00447061380.020
cellular ketone metabolic processGO:0042180510.020
single organism organelle organizationGO:19025891800.020
g protein coupled receptor signaling pathwayGO:00071862420.020
protein localizationGO:00081041910.020
divalent inorganic cation transportGO:00725111340.020
hepatocyte proliferationGO:007257430.020
single organism reproductive processGO:00447022970.020
response to toxic substanceGO:00096361330.020
cellular response to stressGO:00335542690.020
establishment of protein localization to organelleGO:0072594440.019
cellular modified amino acid metabolic processGO:0006575610.019
salivary gland developmentGO:000743130.019
positive regulation of nervous system developmentGO:00519621780.019
intracellular transportGO:00469071850.019
growthGO:00400071650.019
positive regulation of secretionGO:00510471400.019
synaptic transmissionGO:00072682350.019
response to woundingGO:00096112540.019
cellular calcium ion homeostasisGO:00068741600.019
peptidyl tyrosine modificationGO:0018212720.019
epithelial cell differentiationGO:0030855710.018
positive regulation of ion transportGO:0043270940.018
muscle system processGO:00030121150.018
regulation of cell differentiationGO:00455953200.018
secretionGO:00469033070.018
organ regenerationGO:00311001010.018
response to other organismGO:00517072200.018
response to vitaminGO:00332731310.018
liver developmentGO:0001889900.018
regulation of secretion by cellGO:19035302080.018
regulation of cellular amino acid metabolic processGO:000652120.017
rhythmic processGO:00485111560.017
cell projection organizationGO:00300303020.017
carbohydrate derivative metabolic processGO:19011353460.017
chemical homeostasisGO:00488782920.017
programmed cell deathGO:00125013920.017
negative regulation of signal transductionGO:0009968830.017
negative regulation of apoptotic processGO:00430661810.017
negative regulation of transcription dna templatedGO:00458921160.017
ribose phosphate metabolic processGO:00196932350.017
purine nucleotide metabolic processGO:00061632290.017
cytosolic calcium ion homeostasisGO:00514801400.017
multicellular organismal reproductive processGO:00486092330.017
anion transportGO:00068201780.017
organophosphate metabolic processGO:00196373700.017
cellular nitrogen compound catabolic processGO:00442701630.017
organic cyclic compound catabolic processGO:19013611750.017
peptidyl tyrosine phosphorylationGO:0018108720.016
peptide transportGO:0015833970.016
single organism cellular localizationGO:19025801020.016
protein transportGO:00150311320.016
oxidation reduction processGO:00551143040.016
positive regulation of cell differentiationGO:00455972170.016
regulation of protein phosphorylationGO:00019321830.016
regulation of calcium ion transportGO:0051924770.016
regulation of kinase activityGO:00435491170.016
positive regulation of neurogenesisGO:00507691650.016
response to lipopolysaccharideGO:00324961910.016
regulation of nervous system developmentGO:00519602640.016
regulation of secretionGO:00510462240.016
cellular component biogenesisGO:00440853680.015
cellular response to growth factor stimulusGO:00713631620.015
negative regulation of rna biosynthetic processGO:19026791180.015
protein targetingGO:0006605610.015
positive regulation of cellular amine metabolic processGO:003324030.015
cell morphogenesis involved in differentiationGO:00009041190.015
regulation of extracellular matrix constituent secretionGO:000333020.015
coagulationGO:0050817280.015
cellular response to oxidative stressGO:0034599760.015
developmental process involved in reproductionGO:00030061590.015
cellular response to hormone stimulusGO:00328702470.015
negative regulation of cellular protein metabolic processGO:00322691060.015
potassium ion transportGO:0006813970.014
divalent metal ion transportGO:00708381320.014
regulation of immune system processGO:00026821230.014
development of primary sexual characteristicsGO:00451371070.014
intracellular protein transportGO:0006886790.014
nucleoside phosphate metabolic processGO:00067532830.014
negative regulation of nucleic acid templated transcriptionGO:19035071170.014
response to corticosteroidGO:00319602350.014
homeostatic processGO:00425923310.014
protein complex biogenesisGO:00702712630.014
response to oxygen levelsGO:00704822650.014
peptidyl amino acid modificationGO:00181931260.014
artery smooth muscle contractionGO:001482440.014
organic substance catabolic processGO:19015753160.014
regulation of protein modification processGO:00313991940.014
regulation of cellular amine metabolic processGO:003323880.014
purine containing compound metabolic processGO:00725212530.014
multicellular organism reproductionGO:00325042330.014
monocarboxylic acid metabolic processGO:00327871520.014
reactive oxygen species metabolic processGO:0072593370.014
male sex differentiationGO:0046661640.014
immune responseGO:00069551040.013
regulation of body fluid levelsGO:0050878900.013
response to extracellular stimulusGO:00099913800.013
response to glucocorticoidGO:00513842230.013
negative regulation of signalingGO:00230571570.013
dephosphorylationGO:0016311980.013
Human
inorganic ion transmembrane transportGO:00986602290.013
epithelium developmentGO:0060429960.013
negative regulation of kidney developmentGO:009018520.013
sequestering of metal ionGO:005123890.013
small gtpase mediated signal transductionGO:0007264360.013
anatomical structure morphogenesisGO:00096532980.013
regulation of metal ion transportGO:00109591180.013
regulation of reactive oxygen species biosynthetic processGO:190342650.013
cytoplasmic transportGO:00164821150.013
behaviorGO:00076102050.013
cellular protein localizationGO:00346131220.013
multicellular organismal signalingGO:0035637440.013
regulation of phosphorylationGO:00423252480.013
response to corticosteroneGO:0051412400.013
regulation of multicellular organismal developmentGO:20000263760.013
negative regulation of metanephros developmentGO:007221720.012
protein import into nucleusGO:0006606350.012
positive regulation of phosphorus metabolic processGO:00105622620.012
spermatogenesisGO:0007283990.012
gastrulationGO:000736920.012
response to carbohydrateGO:00097431830.012
response to peptideGO:19016522920.012
regulation of canonical wnt signaling pathwayGO:006082840.012
regulation of signal transductionGO:00099663180.012
hormone biosynthetic processGO:0042446250.012
regulation of jak stat cascadeGO:0046425210.012
ras protein signal transductionGO:0007265290.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
regulation of system processGO:00440572080.012
positive regulation of phosphate metabolic processGO:00459372620.012
negative regulation of cell deathGO:00605482290.012
establishment of protein localizationGO:00451841410.012
positive regulation of signal transductionGO:00099671750.012
reactive oxygen species biosynthetic processGO:190340980.012
neuronal action potentialGO:0019228350.012
cellular response to reactive oxygen speciesGO:0034614550.012
glycosyl compound metabolic processGO:19016571820.012
positive regulation of apoptotic processGO:00430651540.012
sex differentiationGO:00075481130.012
hormone secretionGO:00468791150.012
nucleocytoplasmic transportGO:0006913480.012
cellular response to external stimulusGO:00714961180.012
catabolic processGO:00090563510.012
negative regulation of developmental processGO:00510931250.012
metanephric comma shaped body morphogenesisGO:007227820.012
synaptic growth at neuromuscular junctionGO:005112410.012
protein localization to nucleusGO:0034504390.011
male gonad developmentGO:0008584590.011
reactive nitrogen species metabolic processGO:200105710.011
protein targeting to nucleusGO:0044744350.011
rho protein signal transductionGO:0007266110.011
positive regulation of transferase activityGO:0051347810.011
heart morphogenesisGO:000300730.011
cellular response to organic cyclic compoundGO:00714072020.011
steroid biosynthetic processGO:0006694480.011
apoptotic processGO:00069153810.011
chemotaxisGO:0006935660.011
protein complex assemblyGO:00064612630.011
cell cell signalingGO:00072673350.011
negative regulation of rna metabolic processGO:00512531230.011
macromolecular complex assemblyGO:00650032730.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
monovalent inorganic cation transportGO:00156721720.011
tonic smooth muscle contractionGO:001482040.011
axis specificationGO:000979840.011
positive regulation of signalingGO:00230562700.011
single organism biosynthetic processGO:00447113420.011
hormone metabolic processGO:0042445690.010
regulation of neurogenesisGO:00507672470.010
single organism nuclear importGO:1902593350.010
cellular response to hypoxiaGO:0071456510.010
small molecule biosynthetic processGO:00442831240.010
neuron projection developmentGO:00311752730.010
ossificationGO:0001503700.010
ion transmembrane transportGO:00342203650.010
energy derivation by oxidation of organic compoundsGO:0015980460.010
protein heterooligomerizationGO:0051291890.010
brain developmentGO:00074202470.010
circadian rhythmGO:0007623880.010
regulation of t cell migrationGO:200040410.010
morphogenesis of a polarized epitheliumGO:000173810.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
regulation of intracellular signal transductionGO:19025312180.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010

Sh2d4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.014
organ system cancerDOID:005068600.013
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013