Rattus norvegicus

7 known processes

Gzmm

granzyme M (lymphocyte met-ase 1)

Gzmm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of natural killer cell mediated immunityGO:000271640.280
immune system processGO:00023762040.270
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.214
rna biosynthetic processGO:00327743800.177
inflammatory responseGO:00069541500.158
negative regulation of multicellular organismal processGO:00512412030.156
response to tumor cellGO:000234740.156
negative regulation of innate immune responseGO:004582440.150
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.147
negative regulation of immune response to tumor cellGO:000283820.135
cellular response to organic cyclic compoundGO:00714072020.132
positive regulation of transportGO:00510502450.126
cellular response to oxygen containing compoundGO:19017013860.115
negative regulation of nervous system developmentGO:0051961790.114
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.113
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.109
immune response to tumor cellGO:000241830.101
negative regulation of response to tumor cellGO:000283520.100
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.099
positive regulation of lipid kinase activityGO:009021820.096
blood circulationGO:00080151830.095
organophosphate metabolic processGO:00196373700.088
cell activationGO:0001775970.087
negative regulation of developmental processGO:00510931250.086
positive regulation of multicellular organismal processGO:00512403870.086
negative regulation of macromolecule metabolic processGO:00106052600.085
regulation of immune response to tumor cellGO:000283730.080
negative regulation of nucleobase containing compound metabolic processGO:00459341530.078
cellular amine metabolic processGO:0044106380.073
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.073
cellular response to lipidGO:00713962010.073
programmed cell deathGO:00125013920.072
negative regulation of biosynthetic processGO:00098901680.071
innate immune responseGO:0045087350.069
positive regulation of biosynthetic processGO:00098913190.068
regulation of catalytic activityGO:00507903040.068
apoptotic processGO:00069153810.066
negative regulation of cellular metabolic processGO:00313242810.065
metal ion transportGO:00300012890.065
biological adhesionGO:00226101100.064
natural killer cell mediated immune response to tumor cellGO:000242310.064
circulatory system processGO:00030131830.064
proteolysisGO:00065081750.063
intracellular signal transductionGO:00355563140.063
cellular response to endogenous stimulusGO:00714953770.062
cellular lipid metabolic processGO:00442552080.062
response to insulinGO:00328681330.059
negative regulation of macromolecule biosynthetic processGO:00105581480.059
cell type specific apoptotic processGO:00972851340.058
organ morphogenesisGO:0009887750.058
positive regulation of cellular amine metabolic processGO:003324030.057
ion transmembrane transportGO:00342203650.056
cellular ketone metabolic processGO:0042180510.056
cellular homeostasisGO:00197252520.055
regulation of necroptotic processGO:006054420.055
regulation of purine nucleotide metabolic processGO:19005421150.054
leukocyte cell cell adhesionGO:000715940.054
nucleoside phosphate metabolic processGO:00067532830.052
cellular response to steroid hormone stimulusGO:0071383930.052
negative regulation of cell developmentGO:0010721820.052
cell chemotaxisGO:0060326310.052
negative regulation of nitrogen compound metabolic processGO:00511721610.051
chemical homeostasisGO:00488782920.050
negative regulation of immune system processGO:0002683390.050
negative regulation of cell proliferationGO:00082851190.048
negative regulation of response to stimulusGO:00485851550.048
response to growth factorGO:00708481890.047
regulation of cellular amino acid metabolic processGO:000652120.047
positive regulation of programmed cell deathGO:00430681570.047
amine metabolic processGO:0009308380.046
regulation of hydrolase activityGO:00513361430.046
regulation of phosphorus metabolic processGO:00511743490.046
regulation of cellular localizationGO:00603412630.045
vesicle mediated transportGO:00161921810.045
response to biotic stimulusGO:00096072260.045
regulation of cell proliferationGO:00421273590.045
muscle system processGO:00030121150.044
positive regulation of molecular functionGO:00440932300.042
regulation of molecular functionGO:00650093980.042
positive regulation of necroptotic processGO:006054520.042
protein complex assemblyGO:00064612630.042
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.041
regulation of programmed cell deathGO:00430673410.041
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.041
negative regulation of neurogenesisGO:0050768780.040
nucleotide metabolic processGO:00091172790.040
purine ribonucleotide metabolic processGO:00091502270.039
positive regulation of cellular amino acid metabolic processGO:004576410.039
central nervous system developmentGO:00074173110.037
response to extracellular stimulusGO:00099913800.037
immune responseGO:00069551040.037
cellular response to cytokine stimulusGO:00713451270.037
defense responseGO:00069521940.036
regulation of defense responseGO:0031347680.036
regulation of immune system processGO:00026821230.035
cell adhesionGO:00071551100.035
regulation of cellular protein metabolic processGO:00322682670.035
response to lipopolysaccharideGO:00324961910.035
negative regulation of gene expressionGO:00106291990.034
negative regulation of signalingGO:00230571570.034
leukocyte activationGO:0045321760.034
regulation of cellular amine metabolic processGO:003323880.033
positive regulation of cell proliferationGO:00082842490.032
regulation of nucleic acid templated transcriptionGO:19035063800.032
response to vitaminGO:00332731310.032
transmembrane transportGO:00550854120.032
positive regulation of phosphorylationGO:00423271770.032
regulation of rna metabolic processGO:00512523910.031
muscle contractionGO:0006936880.031
regulation of neurogenesisGO:00507672470.031
regulation of myeloid cell differentiationGO:0045637120.031
epithelial cell differentiationGO:0030855710.031
inorganic cation transmembrane transportGO:00986622020.030
regulation of multicellular organismal developmentGO:20000263760.030
cell projection organizationGO:00300303020.030
regulation of system processGO:00440572080.030
regulation of ion transportGO:00432692450.030
t cell activationGO:0042110290.030
mast cell migrationGO:009753140.029
head developmentGO:00603222470.029
purine containing compound metabolic processGO:00725212530.029
carboxylic acid metabolic processGO:00197522890.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
positive regulation of phosphate metabolic processGO:00459372620.029
protein complex subunit organizationGO:00718223020.029
positive regulation of gene expressionGO:00106282440.029
alcohol metabolic processGO:0006066770.029
circulatory system developmentGO:00723591340.028
enzyme linked receptor protein signaling pathwayGO:00071671160.028
regulation of response to stressGO:00801341260.028
cellular response to organonitrogen compoundGO:00714171970.028
ribonucleotide metabolic processGO:00092592310.028
cation transmembrane transportGO:00986552630.028
cytokine productionGO:0001816610.028
regulation of hormone levelsGO:00108171870.028
single organism reproductive processGO:00447022970.028
positive regulation of purine nucleotide metabolic processGO:1900544910.028
cellular response to alcoholGO:0097306870.028
ribose phosphate metabolic processGO:00196932350.027
cell motilityGO:00488702020.027
neuron differentiationGO:00301823680.027
response to external biotic stimulusGO:00432072210.027
regulation of signal transductionGO:00099663180.027
anatomical structure morphogenesisGO:00096532980.027
regulation of neuron differentiationGO:00456642080.026
response to hexoseGO:00097461440.026
organic substance catabolic processGO:19015753160.026
single organism intracellular transportGO:19025821660.026
inorganic ion transmembrane transportGO:00986602290.026
positive regulation of macromolecule biosynthetic processGO:00105572470.025
negative regulation of metabolic processGO:00098923310.025
nitrogen compound transportGO:00717052290.025
positive regulation of phosphorus metabolic processGO:00105622620.025
lipid metabolic processGO:00066292830.025
cellular amino acid metabolic processGO:00065201070.025
cellular component assemblyGO:00226073600.025
cellular response to growth factor stimulusGO:00713631620.025
cellular component biogenesisGO:00440853680.025
ion homeostasisGO:00508012120.024
cellular chemical homeostasisGO:00550822470.024
regulation of rna biosynthetic processGO:20011413810.024
cellular cation homeostasisGO:00300031800.024
cellular response to nitrogen compoundGO:19016992100.024
localization of cellGO:00516742020.024
temperature homeostasisGO:0001659170.024
positive regulation of cellular biosynthetic processGO:00313282950.023
regulation of cell differentiationGO:00455953200.023
ribose phosphate biosynthetic processGO:0046390870.023
positive regulation of nucleotide metabolic processGO:0045981910.023
regulation of protein phosphorylationGO:00019321830.023
response to carbohydrateGO:00097431830.023
intracellular transportGO:00469071850.023
brain developmentGO:00074202470.023
cellular response to hormone stimulusGO:00328702470.023
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.023
immune effector processGO:0002252530.023
purine nucleotide metabolic processGO:00061632290.022
response to ethanolGO:00454711620.022
myeloid leukocyte activationGO:0002274360.022
response to other organismGO:00517072200.022
negative regulation of cell differentiationGO:0045596990.022
response to inorganic substanceGO:00100353770.022
phospholipid metabolic processGO:0006644610.022
negative regulation of signal transductionGO:0009968830.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
regulation of immune responseGO:0050776550.022
nucleic acid templated transcriptionGO:00976593790.022
response to monosaccharideGO:00342841590.022
rna metabolic processGO:00160704060.022
single organism biosynthetic processGO:00447113420.021
epithelium developmentGO:0060429960.021
homeostatic processGO:00425923310.021
response to oxygen levelsGO:00704822650.021
regulation of secretion by cellGO:19035302080.021
actin cytoskeleton organizationGO:0030036730.021
positive regulation of fever generationGO:003162250.021
cgmp biosynthetic processGO:0006182150.021
positive regulation of cell deathGO:00109421840.021
cytoplasmic transportGO:00164821150.021
response to nutrient levelsGO:00316673700.021
development of primary sexual characteristicsGO:00451371070.021
regulation of phosphate metabolic processGO:00192203490.021
positive regulation of cellular component movementGO:00512721020.021
negative regulation of neuron differentiationGO:0045665620.021
response to reactive oxygen speciesGO:00003021200.021
hematopoietic or lymphoid organ developmentGO:0048534360.021
cell morphogenesisGO:00009021420.021
carbohydrate derivative metabolic processGO:19011353460.020
transcription dna templatedGO:00063513770.020
response to purine containing compoundGO:00140741260.020
regulation of neuron projection developmentGO:00109751610.020
protein phosphorylationGO:00064683450.020
forebrain developmentGO:0030900980.020
eye morphogenesisGO:004859240.020
organic acid metabolic processGO:00060822920.020
positive regulation of rna biosynthetic processGO:19026801970.020
cellular response to molecule of bacterial originGO:0071219560.020
monocarboxylic acid metabolic processGO:00327871520.019
catabolic processGO:00090563510.019
regulation of peptide transportGO:0090087870.019
response to corticosteroidGO:00319602350.019
chemokine mediated signaling pathwayGO:007009850.019
regulation of response to tumor cellGO:000283430.019
positive regulation of nervous system developmentGO:00519621780.019
reproductionGO:00000032450.019
eosinophil migrationGO:007267730.019
carboxylic acid transportGO:00469421150.019
cellular response to alkaloidGO:0071312250.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
response to hydrogen peroxideGO:0042542890.018
cellular potassium ion transportGO:0071804720.018
response to hypoxiaGO:00016662310.018
necroptotic processGO:007026620.018
positive regulation of rna metabolic processGO:00512542030.018
rhythmic processGO:00485111560.018
response to estrogenGO:00436272320.018
response to peptideGO:19016522920.018
regulation of transcription dna templatedGO:00063553740.018
retinal ganglion cell axon guidanceGO:003129010.018
response to cgmpGO:007030530.018
b cell activation involved in immune responseGO:000231210.018
nucleobase containing small molecule metabolic processGO:00550863160.018
response to oxidative stressGO:00069791860.018
regulation of cellular ketone metabolic processGO:0010565270.018
organophosphate biosynthetic processGO:00904071430.018
alpha beta t cell activationGO:004663130.018
leukocyte mediated immunityGO:0002443280.018
response to nutrientGO:00075842480.017
positive regulation of response to stimulusGO:00485842850.017
cellular response to oxidative stressGO:0034599760.017
positive regulation of calcium ion transportGO:0051928360.017
leukocyte migrationGO:0050900380.017
response to metal ionGO:00100382530.017
macromolecular complex subunit organizationGO:00439333390.017
positive regulation of hydrolase activityGO:0051345860.017
gonad developmentGO:00084061040.017
cellular catabolic processGO:00442482950.017
lymphocyte activationGO:0046649430.017
cellular component morphogenesisGO:00329891550.017
protein oligomerizationGO:00512591910.017
regulation of muscle contractionGO:0006937530.017
myeloid leukocyte migrationGO:0097529200.017
organic acid transportGO:00158491160.016
t cell proliferationGO:0042098190.016
sexual reproductionGO:00199531480.016
regulation of cell developmentGO:00602842630.016
response to organophosphorusGO:00466831020.016
positive regulation of immune responseGO:0050778420.016
striated muscle contractionGO:0006941440.016
positive regulation of necrotic cell deathGO:001094040.016
cardiovascular system developmentGO:00723581340.016
gastrulationGO:000736920.016
tumor necrosis factor mediated signaling pathwayGO:003320940.016
cyclic nucleotide metabolic processGO:0009187800.016
regulation of apoptotic processGO:00429813350.016
regulation of natural killer cell mediated immunityGO:000271560.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
negative regulation of leukocyte mediated immunityGO:000270460.015
cellular component movementGO:00069282480.015
protein complex biogenesisGO:00702712630.015
sequestering of metal ionGO:005123890.015
oxoacid metabolic processGO:00434362900.015
secretionGO:00469033070.015
g protein coupled receptor signaling pathwayGO:00071862420.015
secretion by cellGO:00329402480.015
response to activityGO:0014823730.015
multicellular organism reproductionGO:00325042330.015
amide transportGO:00428861050.015
positive regulation of transcription dna templatedGO:00458931970.015
negative regulation of immune responseGO:0050777150.015
negative regulation of cellular biosynthetic processGO:00313271610.015
b cell mediated immunityGO:001972440.014
cellular response to lipopolysaccharideGO:0071222550.014
vascular process in circulatory systemGO:0003018960.014
smooth muscle cell proliferationGO:0048659770.014
positive regulation of protein modification processGO:00314011420.014
glycerolipid metabolic processGO:0046486670.014
divalent inorganic cation transportGO:00725111340.014
regulation of nucleotide metabolic processGO:00061401170.014
cellular response to tumor necrosis factorGO:0071356460.014
multicellular organismal homeostasisGO:0048871490.014
positive regulation of cellular protein metabolic processGO:00322701670.014
nucleotide biosynthetic processGO:0009165980.014
regulation of homeostatic processGO:00328441010.014
humoral immune responseGO:0006959120.014
sex differentiationGO:00075481130.014
positive regulation of cell activationGO:0050867340.013
negative regulation of molecular functionGO:00440921330.013
positive regulation of smooth muscle cell migrationGO:0014911270.013
carbohydrate derivative biosynthetic processGO:19011371240.013
positive regulation of protein metabolic processGO:00512471780.013
positive regulation of cell developmentGO:00107201760.013
glucose homeostasisGO:0042593750.013
regulation of metal ion transportGO:00109591180.013
transcription from rna polymerase ii promoterGO:00063662520.013
cellular metal ion homeostasisGO:00068751720.013
response to acid chemicalGO:00011012220.013
gamete generationGO:00072761240.013
cellular ion homeostasisGO:00068731840.013
multicellular organismal reproductive processGO:00486092330.013
positive regulation of angiogenesisGO:0045766280.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
response to cytokineGO:00340972150.013
macromolecule localizationGO:00330362520.013
cell cell signaling involved in cell fate commitmentGO:004516820.012
positive regulation of defense responseGO:0031349370.012
regulation of lymphocyte chemotaxisGO:190162310.012
regulation of vesicle mediated transportGO:0060627810.012
negative regulation of catalytic activityGO:00430861030.012
regulation of nervous system developmentGO:00519602640.012
regulation of synaptic transmissionGO:00508041410.012
myeloid leukocyte differentiationGO:0002573200.012
response to glucocorticoidGO:00513842230.012
regulation of hormone secretionGO:00468831060.012
lipid catabolic processGO:0016042460.012
negative regulation of secretion by cellGO:1903531720.012
tissue developmentGO:00098882520.012
regulation of cytokine productionGO:0001817560.012
neuron developmentGO:00486662860.012
protein maturationGO:0051604680.012
negative regulation of programmed cell deathGO:00430691830.012
cyclic nucleotide biosynthetic processGO:0009190630.012
regulation of cell motilityGO:20001451310.012
negative regulation of neuron projection developmentGO:0010977460.012
immune system developmentGO:0002520410.012
response to campGO:0051591910.012
protein processingGO:0016485680.012
negative regulation of defense responseGO:0031348190.012
hemopoiesisGO:0030097340.012
retina morphogenesis in camera type eyeGO:006004210.012
regulation of muscle cell apoptotic processGO:0010660260.012
response to bacteriumGO:00096172000.012
peptidyl amino acid modificationGO:00181931260.011
negative regulation of rna metabolic processGO:00512531230.011
kidney developmentGO:0001822670.011
regulation of acute inflammatory responseGO:0002673230.011
positive regulation of cellular component organizationGO:00511302000.011
cellular macromolecule catabolic processGO:0044265290.011
behaviorGO:00076102050.011
male sex differentiationGO:0046661640.011
glial cell differentiationGO:0010001650.011
viral genome replicationGO:001907920.011
eosinophil chemotaxisGO:004824530.011
cellular response to glucocorticoid stimulusGO:0071385680.011
reproductive processGO:00224143720.011
positive regulation of protein kinase activityGO:0045860730.011
positive regulation of cell differentiationGO:00455972170.011
negative regulation of leukocyte apoptotic processGO:200010740.011
monocarboxylic acid catabolic processGO:0072329280.011
negative regulation of apoptotic processGO:00430661810.011
organic cyclic compound catabolic processGO:19013611750.011
single organism organelle organizationGO:19025891800.011
positive regulation of neuron apoptotic processGO:0043525330.011
macromolecular complex assemblyGO:00650032730.011
adult locomotory behaviorGO:000834440.011
purine containing compound biosynthetic processGO:0072522850.011
response to tumor necrosis factorGO:0034612560.011
positive regulation of leukocyte activationGO:0002696300.011
regulation of membrane potentialGO:00423911100.011
positive regulation of cell motilityGO:2000147970.011
single organism cell adhesionGO:0098602460.011
developmental process involved in reproductionGO:00030061590.011
cation transportGO:00068123820.011
anterior posterior pattern specificationGO:000995210.011
formation of primary germ layerGO:000170410.011
regulation of protein localizationGO:0032880810.011
regulation of anatomical structure morphogenesisGO:00226031410.011
single organism cellular localizationGO:19025801020.011
transmission of nerve impulseGO:0019226420.011
positive regulation of ion transportGO:0043270940.011
regulation of peptide secretionGO:0002791820.010
positive regulation of cell communicationGO:00106472710.010
positive regulation of immune system processGO:0002684900.010
divalent metal ion transportGO:00708381320.010
negative regulation of cell communicationGO:00106481580.010
positive regulation of neuron differentiationGO:00456661260.010
morphogenesis of embryonic epitheliumGO:001633130.010
alcohol biosynthetic processGO:0046165380.010
rho protein signal transductionGO:0007266110.010
lymphocyte proliferationGO:0046651290.010
sensory perceptionGO:00076001010.010
neuron projection developmentGO:00311752730.010
smooth muscle contractionGO:0006939370.010
cellular response to biotic stimulusGO:0071216590.010
agingGO:00075682410.010
negative regulation of cell deathGO:00605482290.010
regulation of apoptotic signaling pathwayGO:2001233130.010
divalent inorganic cation homeostasisGO:00725071650.010
positive regulation of nucleic acid templated transcriptionGO:19035081970.010
camera type eye morphogenesisGO:004859320.010
response to morphineGO:0043278270.010
peptidyl tyrosine phosphorylationGO:0018108720.010
antigen processing and presentationGO:001988220.010

Gzmm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
musculoskeletal system diseaseDOID:1700.035
connective tissue diseaseDOID:6500.032
nervous system diseaseDOID:86300.030
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015
eye diseaseDOID:561400.015
lymphatic system diseaseDOID:7500.014
immune system diseaseDOID:291400.014
retinal diseaseDOID:567900.013
retinal degenerationDOID:846600.013
bone diseaseDOID:008000100.010