Rattus norvegicus

62 known processes

Ptges

prostaglandin E synthase

(Aliases: MGC124930,Pges)

Ptges biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to molecule of bacterial originGO:00022371940.308
response to other organismGO:00517072200.287
response to lipopolysaccharideGO:00324961910.180
regulation of cell motilityGO:20001451310.169
single organism reproductive processGO:00447022970.160
Rat
cation transportGO:00068123820.149
response to bacteriumGO:00096172000.133
response to biotic stimulusGO:00096072260.132
lipid metabolic processGO:00066292830.118
regulation of cell proliferationGO:00421273590.111
macromolecular complex assemblyGO:00650032730.108
Rat
cellular amino acid metabolic processGO:00065201070.104
regulation of cellular component organizationGO:00511283680.100
female pregnancyGO:00075651220.096
organic acid metabolic processGO:00060822920.096
cellular response to cytokine stimulusGO:00713451270.092
regulation of neuron differentiationGO:00456642080.090
positive regulation of developmental processGO:00510942830.090
positive regulation of cellular component organizationGO:00511302000.089
protein complex assemblyGO:00064612630.088
Rat
response to nutrient levelsGO:00316673700.086
regulation of programmed cell deathGO:00430673410.086
response to purine containing compoundGO:00140741260.086
multi multicellular organism processGO:00447061380.084
regulation of anatomical structure morphogenesisGO:00226031410.084
regulation of protein metabolic processGO:00512462890.084
apoptotic processGO:00069153810.083
response to peptide hormoneGO:00434342780.082
negative regulation of cell proliferationGO:00082851190.082
regulation of system processGO:00440572080.081
response to mechanical stimulusGO:00096121340.081
transmission of nerve impulseGO:0019226420.079
response to organophosphorusGO:00466831020.079
response to peptideGO:19016522920.079
response to woundingGO:00096112540.078
reproductive system developmentGO:00614581280.075
Rat
anatomical structure morphogenesisGO:00096532980.073
protein complex biogenesisGO:00702712630.073
Rat
locomotionGO:00400112370.073
response to acid chemicalGO:00011012220.073
regulation of multicellular organismal developmentGO:20000263760.072
positive regulation of cell motilityGO:2000147970.071
wound healingGO:00420601220.070
cellular ketone metabolic processGO:0042180510.068
programmed cell deathGO:00125013920.068
reproductive processGO:00224143720.067
Rat
neuron developmentGO:00486662860.067
development of primary sexual characteristicsGO:00451371070.067
Rat
organic substance catabolic processGO:19015753160.064
protein homooligomerizationGO:0051260910.064
Rat
amine metabolic processGO:0009308380.063
cellular response to oxygen containing compoundGO:19017013860.061
cellular amine metabolic processGO:0044106380.061
regulation of secretionGO:00510462240.061
nitrogen compound transportGO:00717052290.061
tissue developmentGO:00098882520.060
cell cell signalingGO:00072673350.060
reproductionGO:00000032450.059
organic anion transportGO:00157111320.059
response to campGO:0051591910.059
sexual reproductionGO:00199531480.059
neuron differentiationGO:00301823680.058
developmental process involved in reproductionGO:00030061590.057
Rat
glomerular epithelial cell differentiationGO:007231120.056
neurological system processGO:00508772190.056
heart morphogenesisGO:000300730.056
regulation of cell differentiationGO:00455953200.055
carboxylic acid metabolic processGO:00197522890.054
cellular response to organonitrogen compoundGO:00714171970.054
multi organism reproductive processGO:00447032620.053
cellular response to lipopolysaccharideGO:0071222550.053
small molecule biosynthetic processGO:00442831240.052
response to external biotic stimulusGO:00432072210.052
anion transportGO:00068201780.052
cellular response to molecule of bacterial originGO:0071219560.051
response to decreased oxygen levelsGO:00362932370.051
cellular component biogenesisGO:00440853680.051
Rat
regulation of apoptotic processGO:00429813350.051
circulatory system developmentGO:00723591340.050
response to estradiolGO:00323551640.049
protein oligomerizationGO:00512591910.049
Rat
positive regulation of protein metabolic processGO:00512471780.049
head developmentGO:00603222470.049
monovalent inorganic cation transportGO:00156721720.048
single organism biosynthetic processGO:00447113420.048
cellular cation homeostasisGO:00300031800.047
cellular response to organic cyclic compoundGO:00714072020.047
regulation of cell developmentGO:00602842630.047
response to cytokineGO:00340972150.046
reactive oxygen species metabolic processGO:0072593370.046
regulation of phosphorylationGO:00423252480.046
cell migrationGO:00164771970.046
cellular response to interleukin 1GO:0071347370.046
positive regulation of transportGO:00510502450.046
regulation of nervous system developmentGO:00519602640.046
negative regulation of developmental processGO:00510931250.045
regulation of cell projection organizationGO:00313441750.044
response to vitaminGO:00332731310.044
positive regulation of cell deathGO:00109421840.044
secretionGO:00469033070.043
hormone metabolic processGO:0042445690.043
regulation of locomotionGO:00400121480.043
cellular calcium ion homeostasisGO:00068741600.043
neuronal action potentialGO:0019228350.043
rhythmic processGO:00485111560.042
regulation of cellular amino acid metabolic processGO:000652120.042
reproductive structure developmentGO:00486081280.042
Rat
calcium ion homeostasisGO:00550741620.041
regulation of transcription dna templatedGO:00063553740.041
response to tumor necrosis factorGO:0034612560.041
organic acid transportGO:00158491160.041
regulation of neurogenesisGO:00507672470.041
organ regenerationGO:00311001010.041
positive regulation of cell differentiationGO:00455972170.040
regulation of hormone levelsGO:00108171870.040
response to temperature stimulusGO:0009266940.040
positive regulation of multicellular organismal processGO:00512403870.040
cell projection organizationGO:00300303020.040
ion transmembrane transportGO:00342203650.039
response to hexoseGO:00097461440.039
positive regulation of cell developmentGO:00107201760.039
response to interleukin 1GO:0070555550.038
cellular homeostasisGO:00197252520.037
ion homeostasisGO:00508012120.037
catabolic processGO:00090563510.037
positive regulation of neurogenesisGO:00507691650.037
positive regulation of protein modification processGO:00314011420.037
regulation of cellular amine metabolic processGO:003323880.036
multicellular organism reproductionGO:00325042330.036
positive regulation of cellular amino acid metabolic processGO:004576410.036
cardiovascular system developmentGO:00723581340.036
response to nutrientGO:00075842480.036
positive regulation of cellular biosynthetic processGO:00313282950.035
blood circulationGO:00080151830.035
sex differentiationGO:00075481130.035
Rat
cellular response to tumor necrosis factorGO:0071356460.035
myelinationGO:0042552390.035
regulation of molecular functionGO:00650093980.035
response to ketoneGO:19016541820.035
multicellular organismal reproductive processGO:00486092330.035
cellular chemical homeostasisGO:00550822470.035
response to oxidative stressGO:00069791860.034
localization of cellGO:00516742020.034
signal releaseGO:00230611450.034
brain developmentGO:00074202470.034
cellular response to oxidative stressGO:0034599760.034
response to extracellular stimulusGO:00099913800.034
organic hydroxy compound metabolic processGO:19016151150.034
cell motilityGO:00488702020.033
metal ion transportGO:00300012890.033
positive regulation of cellular amine metabolic processGO:003324030.033
cellular response to lipidGO:00713962010.033
regulation of protein phosphorylationGO:00019321830.032
positive regulation of locomotionGO:00400171020.032
macromolecular complex subunit organizationGO:00439333390.032
Rat
signal transduction by phosphorylationGO:00230141440.032
cation homeostasisGO:00550801950.031
positive regulation of neuron projection developmentGO:0010976990.031
renal system processGO:0003014400.031
divalent inorganic cation homeostasisGO:00725071650.031
cellular catabolic processGO:00442482950.031
prostate gland epithelium morphogenesisGO:006074020.031
multicellular organismal water homeostasisGO:005089140.030
cellular response to endogenous stimulusGO:00714953770.030
transcription dna templatedGO:00063513770.030
growthGO:00400071650.029
regulation of angiogenesisGO:0045765390.029
cellular response to peptide hormone stimulusGO:00713751200.029
cellular protein localizationGO:00346131220.029
regulation of neuron projection developmentGO:00109751610.028
embryonic skeletal system developmentGO:004870630.028
rna biosynthetic processGO:00327743800.028
regulation of cellular protein metabolic processGO:00322682670.028
agingGO:00075682410.028
enzyme linked receptor protein signaling pathwayGO:00071671160.027
organ morphogenesisGO:0009887750.027
anatomical structure formation involved in morphogenesisGO:0048646830.027
positive regulation of response to stimulusGO:00485842850.027
hindlimb morphogenesisGO:003513720.027
regulation of vasculature developmentGO:1901342440.026
cellular response to stressGO:00335542690.026
cellular response to biotic stimulusGO:0071216590.026
positive regulation of cellular component movementGO:00512721020.026
cellular ion homeostasisGO:00068731840.026
positive regulation of kinase activityGO:0033674770.026
positive regulation of nitrogen compound metabolic processGO:00511733340.026
positive regulation of nervous system developmentGO:00519621780.026
cellular response to nitrogen compoundGO:19016992100.026
divalent inorganic cation transportGO:00725111340.026
response to ethanolGO:00454711620.026
eye morphogenesisGO:004859240.025
gonad developmentGO:00084061040.025
Rat
response to inorganic substanceGO:00100353770.025
negative regulation of macromolecule metabolic processGO:00106052600.025
oxoacid metabolic processGO:00434362900.025
cellular hormone metabolic processGO:0034754490.025
organophosphate metabolic processGO:00196373700.025
positive regulation of cell migrationGO:0030335960.025
regulation of protein modification processGO:00313991940.025
response to estrogenGO:00436272320.025
ovulation cycle processGO:0022602500.024
regulation of cellular ketone metabolic processGO:0010565270.024
regulation of intracellular signal transductionGO:19025312180.024
positive regulation of molecular functionGO:00440932300.024
cellular response to peptideGO:19016531330.024
action potentialGO:0001508540.023
positive regulation of cell proliferationGO:00082842490.023
metal ion homeostasisGO:00550651860.023
erythrocyte differentiationGO:003021810.023
response to mineralocorticoidGO:0051385490.023
response to heatGO:0009408600.023
cellular component movementGO:00069282480.023
neuron projection developmentGO:00311752730.023
central nervous system developmentGO:00074173110.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
positive regulation of cell communicationGO:00106472710.023
response to hypoxiaGO:00016662310.023
cellular response to fluid shear stressGO:007149840.023
positive regulation of apoptotic processGO:00430651540.022
intracellular signal transductionGO:00355563140.022
regulation of signal transductionGO:00099663180.022
negative regulation of epithelial cell proliferationGO:0050680160.022
chemical homeostasisGO:00488782920.022
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.022
steroid metabolic processGO:0008202730.022
secretion by cellGO:00329402480.022
hormone transportGO:00099141210.022
negative regulation of cellular metabolic processGO:00313242810.022
synaptic transmissionGO:00072682350.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
cellular response to alcoholGO:0097306870.021
epibolyGO:009050420.021
cellular component assemblyGO:00226073600.021
Rat
regulation of cellular localizationGO:00603412630.021
regenerationGO:00310991630.021
regulation of response to woundingGO:1903034690.021
response to dexamethasoneGO:0071548490.021
protein complex subunit organizationGO:00718223020.021
Rat
regulation of lipid metabolic processGO:0019216680.021
regulation of secretion by cellGO:19035302080.021
positive regulation of neuron differentiationGO:00456661260.021
protein localizationGO:00081041910.020
negative regulation of cell differentiationGO:0045596990.020
transcription from rna polymerase ii promoterGO:00063662520.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
peptidyl amino acid modificationGO:00181931260.020
hormone secretionGO:00468791150.020
positive regulation of protein phosphorylationGO:00019341350.020
cell cycleGO:00070491010.020
response to glucoseGO:00097491360.020
blood vessel developmentGO:0001568690.020
negative regulation of transcription dna templatedGO:00458921160.020
gland developmentGO:00487321550.020
negative regulation of multicellular organismal processGO:00512412030.020
regulation of blood pressureGO:0008217830.020
response to corticosteroidGO:00319602350.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
positive regulation of phosphorus metabolic processGO:00105622620.020
regulation of blood vessel sizeGO:0050880890.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
organonitrogen compound biosynthetic processGO:19015661670.019
blood vessel morphogenesisGO:0048514580.019
defense responseGO:00069521940.019
vasculature developmentGO:0001944700.019
positive regulation of cellular protein metabolic processGO:00322701670.019
glomerular visceral epithelial cell developmentGO:007201520.019
epiboly involved in wound healingGO:009050520.019
retina morphogenesis in camera type eyeGO:006004210.019
alcohol metabolic processGO:0006066770.019
regulation of body fluid levelsGO:0050878900.019
cellular metal ion homeostasisGO:00068751720.019
regulation of systemic arterial blood pressureGO:0003073300.019
positive regulation of transferase activityGO:0051347810.019
positive regulation of signal transductionGO:00099671750.019
rna metabolic processGO:00160704060.019
positive regulation of cell projection organizationGO:00313461110.019
regulation of catalytic activityGO:00507903040.019
response to activityGO:0014823730.018
regulation of reactive oxygen species metabolic processGO:2000377260.018
cell differentiation involved in kidney developmentGO:006100540.018
regulation of protein kinase activityGO:00458591050.018
response to monosaccharideGO:00342841590.018
single organism catabolic processGO:00447122830.018
negative regulation of hormone secretionGO:0046888460.018
positive regulation of gene expressionGO:00106282440.018
cellular response to external stimulusGO:00714961180.018
angiogenesisGO:0001525530.018
axon ensheathmentGO:0008366400.018
neuron deathGO:00709971270.018
macromolecule localizationGO:00330362520.018
regulation of cell migrationGO:00303341280.018
response to retinoic acidGO:0032526630.018
regulation of rna metabolic processGO:00512523910.018
negative regulation of secretionGO:0051048820.018
response to radiationGO:00093141370.018
positive regulation of secretionGO:00510471400.018
regulation of response to stressGO:00801341260.018
lung developmentGO:0030324430.017
positive regulation of phosphorylationGO:00423271770.017
proteolysisGO:00065081750.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
amide transportGO:00428861050.017
negative regulation of programmed cell deathGO:00430691830.017
regulation of rna biosynthetic processGO:20011413810.017
embryonic hindlimb morphogenesisGO:003511620.017
embryonic cranial skeleton morphogenesisGO:004870120.017
carbohydrate derivative metabolic processGO:19011353460.017
homeostatic processGO:00425923310.017
skeletal system developmentGO:0001501410.017
cellular response to acid chemicalGO:0071229750.017
monocarboxylic acid metabolic processGO:00327871520.017
negative regulation of cell deathGO:00605482290.017
regulation of fat cell differentiationGO:004559830.017
response to ionizing radiationGO:0010212590.017
regulation of transferase activityGO:00513381230.017
cellular lipid metabolic processGO:00442552080.017
regulation of hormone secretionGO:00468831060.016
protein phosphorylationGO:00064683450.016
hematopoietic progenitor cell differentiationGO:000224420.016
regulation of calcium ion transportGO:0051924770.016
sensory perceptionGO:00076001010.016
negative regulation of cell developmentGO:0010721820.016
response to carbohydrateGO:00097431830.016
response to glucocorticoidGO:00513842230.016
multicellular organismal signalingGO:0035637440.016
cellular response to reactive oxygen speciesGO:0034614550.016
response to growth factorGO:00708481890.016
response to vitamin dGO:0033280340.016
immune responseGO:00069551040.016
ovulation cycleGO:0042698670.015
male sex differentiationGO:0046661640.015
Rat
regulation of membrane potentialGO:00423911100.015
regulation of cell adhesionGO:0030155520.015
gamete generationGO:00072761240.015
peptidyl tyrosine phosphorylationGO:0018108720.015
negative regulation of rna metabolic processGO:00512531230.015
cellular response to growth factor stimulusGO:00713631620.015
multicellular organism growthGO:003526410.015
positive regulation of cytokine secretionGO:005071590.015
tissue morphogenesisGO:0048729220.015
male gonad developmentGO:0008584590.015
Rat
response to reactive oxygen speciesGO:00003021200.015
ossificationGO:0001503700.015
protein maturationGO:0051604680.015
bmp signaling pathwayGO:003050940.015
negative regulation of neurogenesisGO:0050768780.014
positive regulation of neuron migrationGO:200122420.014
negative regulation of metabolic processGO:00098923310.014
cellular response to metal ionGO:0071248550.014
positive regulation of catalytic activityGO:00430851840.014
negative regulation of rna biosynthetic processGO:19026791180.014
regulation of cellular component movementGO:00512701500.014
acute inflammatory responseGO:0002526580.014
positive regulation of signalingGO:00230562700.014
cellular modified amino acid metabolic processGO:0006575610.014
reactive oxygen species biosynthetic processGO:190340980.014
positive regulation of fat cell differentiationGO:004560020.014
lipid storageGO:001991510.014
negative regulation of gene expressionGO:00106291990.014
oxidation reduction processGO:00551143040.014
regulation of response to external stimulusGO:00321011060.014
regulation of proteolysisGO:0030162660.013
regulation of cell morphogenesisGO:0022604770.013
carboxylic acid transportGO:00469421150.013
glucose homeostasisGO:0042593750.013
coenzyme metabolic processGO:0006732860.013
peptide transportGO:0015833970.013
urogenital system developmentGO:0001655780.013
development of primary female sexual characteristicsGO:0046545560.013
developmental growthGO:00485891000.013
cell growthGO:00160491040.013
negative regulation of protein metabolic processGO:00512481140.013
prostate gland morphogenesisGO:006051220.013
response to fluid shear stressGO:0034405160.013
ameboidal type cell migrationGO:0001667260.013
lipid biosynthetic processGO:00086101280.013
intracellular transportGO:00469071850.013
immune system processGO:00023762040.013
sensory perception of light stimulusGO:005095330.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
tissue regenerationGO:0042246360.013
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.013
axis specificationGO:000979840.013
muscle system processGO:00030121150.013
negative regulation of cellular biosynthetic processGO:00313271610.013
negative regulation of molecular functionGO:00440921330.013
regulation of canonical wnt signaling pathwayGO:006082840.013
embryonic appendage morphogenesisGO:003511340.013
response to corticosteroneGO:0051412400.013
cellular response to insulin stimulusGO:0032869810.013
epithelial cell differentiation involved in kidney developmentGO:003585030.012
cell morphogenesisGO:00009021420.012
positive regulation of secretion by cellGO:19035321280.012
regulation of phosphate metabolic processGO:00192203490.012
cytosolic calcium ion homeostasisGO:00514801400.012
regulation of protein localizationGO:0032880810.012
single organism organelle organizationGO:19025891800.012
positive regulation of cell activationGO:0050867340.012
positive regulation of biosynthetic processGO:00098913190.012
epidermis developmentGO:0008544110.012
camera type eye morphogenesisGO:004859320.012
negative regulation of cell communicationGO:00106481580.012
cellular response to campGO:0071320260.012
regulation of neuron deathGO:19012141150.012
transmembrane transportGO:00550854120.012
regulation of phosphorus metabolic processGO:00511743490.012
organonitrogen compound catabolic processGO:19015651790.012
peptide metabolic processGO:0006518320.012
behaviorGO:00076102050.012
calcium ion transportGO:00068161310.012
positive regulation of smooth muscle cell proliferationGO:0048661510.012
regulation of ossificationGO:0030278320.012
fatty acid biosynthetic processGO:0006633330.012
defense response to gram negative bacteriumGO:005082930.012
regulation of cell growthGO:0001558850.012
response to insulinGO:00328681330.012
erythrocyte homeostasisGO:003410120.012
respiratory tube developmentGO:0030323430.012
response to progesteroneGO:0032570480.012
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
response to electrical stimulusGO:0051602560.011
regulation of lipid biosynthetic processGO:0046890380.011
response to amino acidGO:0043200750.011
interleukin 1 secretionGO:005070130.011
positive regulation of defense responseGO:0031349370.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
positive regulation of ion transportGO:0043270940.011
lipid localizationGO:0010876620.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
nucleobase containing compound catabolic processGO:00346551520.011
negative regulation of kidney developmentGO:009018520.011
regulation of endothelial cell apoptotic processGO:200035130.011
hepaticobiliary system developmentGO:0061008900.011
fatty acid derivative metabolic processGO:1901568380.011
response to oxygen levelsGO:00704822650.011
negative regulation of biosynthetic processGO:00098901680.011
regulation of smooth muscle cell proliferationGO:0048660750.011
amino acid transmembrane transportGO:0003333330.011
cation transmembrane transportGO:00986552630.011
regulation of anion transportGO:0044070430.011
renal filtration cell differentiationGO:006131820.011
respiratory system developmentGO:0060541450.011
cellular response to interferon gammaGO:0071346140.011
ensheathment of neuronsGO:0007272400.011
negative regulation of mitotic cell cycle phase transitionGO:190199130.011
female gonad developmentGO:0008585530.011
embryonic limb morphogenesisGO:003032640.011
gastrulationGO:000736920.011
organelle organizationGO:00069962660.011
axon developmentGO:0061564960.011
regulation of tube sizeGO:0035150890.011
negative regulation of transportGO:00510511360.011
embryonic skeletal system morphogenesisGO:004870430.010
salivary gland morphogenesisGO:000743510.010
vasoconstrictionGO:0042310540.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
muscle structure developmentGO:0061061870.010
positive regulation of rna metabolic processGO:00512542030.010
gliogenesisGO:0042063930.010
regulation of cell cycleGO:0051726730.010
peptidyl tyrosine modificationGO:0018212720.010
regulation of peptide transportGO:0090087870.010
negative regulation of cellular component organizationGO:0051129830.010
inflammatory responseGO:00069541500.010
response to transition metal nanoparticleGO:19902671220.010
amino acid transportGO:0006865700.010
morphogenesis of embryonic epitheliumGO:001633130.010
sodium ion transportGO:0006814820.010
positive regulation of response to woundingGO:1903036340.010
positive regulation of phosphate metabolic processGO:00459372620.010

Ptges disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.050
urinary system diseaseDOID:1800.050
kidney diseaseDOID:55700.038
nervous system diseaseDOID:86300.029
retinal degenerationDOID:846600.029
retinal diseaseDOID:567900.029
eye diseaseDOID:561400.029
eye and adnexa diseaseDOID:149200.029
sensory system diseaseDOID:005015500.029
retinitis pigmentosaDOID:1058400.029
renal tubular transport diseaseDOID:44700.025
bone diseaseDOID:008000100.017
musculoskeletal system diseaseDOID:1700.017
connective tissue diseaseDOID:6500.017
disease of cellular proliferationDOID:1456600.010