Rattus norvegicus

103 known processes

Btk

Bruton agammaglobulinemia tyrosine kinase

Btk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune response regulating signaling pathwayGO:0002764190.219
Rat
purine ribonucleoside triphosphate metabolic processGO:00092051400.154
nucleoside metabolic processGO:00091161790.129
lymphocyte migrationGO:007267630.123
nucleoside catabolic processGO:00091641260.118
cell activationGO:0001775970.104
regulation of cellular ketone metabolic processGO:0010565270.104
purine ribonucleoside catabolic processGO:00461301240.102
organic acid metabolic processGO:00060822920.101
response to molecule of bacterial originGO:00022371940.097
Rat
immune response activating signal transductionGO:0002757150.093
Rat
immune responseGO:00069551040.090
cellular amino acid metabolic processGO:00065201070.087
immune system processGO:00023762040.087
positive regulation of response to stimulusGO:00485842850.082
Rat
cellular calcium ion homeostasisGO:00068741600.077
Rat
nucleoside phosphate metabolic processGO:00067532830.076
response to biotic stimulusGO:00096072260.076
regulation of immune system processGO:00026821230.072
Rat
regulation of cellular amino acid metabolic processGO:000652120.070
ribonucleoside catabolic processGO:00424541260.069
cation homeostasisGO:00550801950.068
Rat
purine containing compound metabolic processGO:00725212530.068
t cell migrationGO:007267820.068
purine ribonucleotide catabolic processGO:00091541360.065
purine containing compound catabolic processGO:00725231380.065
cellular amine metabolic processGO:0044106380.065
organophosphate metabolic processGO:00196373700.063
Rat
glycosyl compound metabolic processGO:19016571820.061
regulation of cellular amine metabolic processGO:003323880.061
ribonucleoside metabolic processGO:00091191740.060
regulation of phosphate metabolic processGO:00192203490.060
Rat
oxoacid metabolic processGO:00434362900.058
negative regulation of metabolic processGO:00098923310.057
Rat
single organism intracellular transportGO:19025821660.056
positive regulation of immune system processGO:0002684900.054
Rat
atp metabolic processGO:0046034720.053
ribonucleoside triphosphate metabolic processGO:00091991410.052
positive regulation of biosynthetic processGO:00098913190.051
Rat
amine metabolic processGO:0009308380.050
carboxylic acid metabolic processGO:00197522890.049
nucleobase containing small molecule metabolic processGO:00550863160.048
regulation of phosphorus metabolic processGO:00511743490.048
Rat
carbohydrate derivative catabolic processGO:19011361470.047
behaviorGO:00076102050.047
Fly
carbohydrate derivative metabolic processGO:19011353460.046
nucleoside triphosphate metabolic processGO:00091411440.046
lipid metabolic processGO:00066292830.046
Rat
organophosphate catabolic processGO:00464341480.045
regulation of cellular localizationGO:00603412630.044
Rat
nucleotide metabolic processGO:00091172790.043
organonitrogen compound catabolic processGO:19015651790.042
macromolecule localizationGO:00330362520.042
Rat
regulation of locomotionGO:00400121480.042
Rat
programmed cell deathGO:00125013920.041
Rat
cellular response to oxygen containing compoundGO:19017013860.041
response to other organismGO:00517072200.041
antigen receptor mediated signaling pathwayGO:005085110.041
regenerationGO:00310991630.040
Rat
single organism membrane organizationGO:0044802740.040
ribonucleoside triphosphate catabolic processGO:00092031220.040
positive regulation of cellular amino acid metabolic processGO:004576410.040
chemical homeostasisGO:00488782920.040
Rat
protein complex subunit organizationGO:00718223020.040
Fly
positive regulation of transcription factor import into nucleusGO:004299340.040
positive regulation of protein metabolic processGO:00512471780.039
Rat
glycosyl compound catabolic processGO:19016581260.039
nucleoside monophosphate catabolic processGO:0009125560.039
macromolecular complex subunit organizationGO:00439333390.038
Fly
positive regulation of immune responseGO:0050778420.038
Rat
nucleobase containing compound catabolic processGO:00346551520.038
divalent inorganic cation homeostasisGO:00725071650.038
Rat
ribonucleotide catabolic processGO:00092611360.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
Rat
regulation of secretion by cellGO:19035302080.037
Rat
cytosolic calcium ion homeostasisGO:00514801400.037
Rat
defense responseGO:00069521940.036
ion homeostasisGO:00508012120.036
Rat
positive regulation of cellular component movementGO:00512721020.036
Rat
nucleoside phosphate catabolic processGO:19012921400.035
ribose phosphate metabolic processGO:00196932350.034
nucleotide catabolic processGO:00091661390.034
metal ion homeostasisGO:00550651860.034
Rat
cellular chemical homeostasisGO:00550822470.033
Rat
purine nucleoside triphosphate catabolic processGO:00091461220.033
single organism catabolic processGO:00447122830.033
heterocycle catabolic processGO:00467001670.033
cellular nitrogen compound catabolic processGO:00442701630.032
cytokine productionGO:0001816610.032
Rat
inflammatory responseGO:00069541500.032
positive regulation of phosphorus metabolic processGO:00105622620.032
Rat
cellular ketone metabolic processGO:0042180510.032
protein phosphorylationGO:00064683450.032
response to lipopolysaccharideGO:00324961910.032
Rat
gland developmentGO:00487321550.032
Fly
response to metal ionGO:00100382530.031
Rat
g protein coupled receptor signaling pathwayGO:00071862420.031
regulation of molecular functionGO:00650093980.030
Rat
positive regulation of cellular amine metabolic processGO:003324030.030
cellular protein localizationGO:00346131220.030
response to inorganic substanceGO:00100353770.030
Rat
response to carbohydrateGO:00097431830.029
Rat
cellular component movementGO:00069282480.029
Rat
purine nucleoside metabolic processGO:00422781690.029
secretionGO:00469033070.029
positive regulation of signalingGO:00230562700.029
Rat
calcium ion homeostasisGO:00550741620.028
Rat
cellular divalent inorganic cation homeostasisGO:00725031620.028
Rat
regulation of protein modification processGO:00313991940.028
Rat
reproductive processGO:00224143720.028
Fly
transcription dna templatedGO:00063513770.027
Rat
purine nucleotide catabolic processGO:00061951360.027
purine ribonucleoside metabolic processGO:00461281680.027
small molecule biosynthetic processGO:00442831240.027
atp catabolic processGO:0006200540.027
purine ribonucleoside monophosphate metabolic processGO:0009167840.027
peptidyl amino acid modificationGO:00181931260.026
reactive oxygen species metabolic processGO:0072593370.026
cellular homeostasisGO:00197252520.026
Rat
response to growth factorGO:00708481890.026
Rat
erk1 and erk2 cascadeGO:0070371480.026
Rat
purine nucleoside triphosphate metabolic processGO:00091441410.026
intracellular signal transductionGO:00355563140.025
Mouse Rat
vesicle mediated transportGO:00161921810.025
negative regulation of cellular metabolic processGO:00313242810.025
Rat
leukocyte activationGO:0045321760.024
response to acid chemicalGO:00011012220.024
Rat
organic cyclic compound catabolic processGO:19013611750.024
multicellular organismal reproductive processGO:00486092330.024
Fly
nucleoside monophosphate metabolic processGO:0009123930.024
cellular response to lipopolysaccharideGO:0071222550.024
Rat
homeostatic processGO:00425923310.024
Rat
regulation of establishment of protein localizationGO:0070201690.023
Rat
catabolic processGO:00090563510.023
purine nucleoside monophosphate metabolic processGO:0009126840.023
regulation of lymphocyte migrationGO:200040110.023
response to nutrientGO:00075842480.023
response to peptide hormoneGO:00434342780.023
Rat
protein secretionGO:0009306340.023
Rat
purine ribonucleoside monophosphate catabolic processGO:0009169550.023
cellular response to endogenous stimulusGO:00714953770.023
Rat
positive regulation of developmental processGO:00510942830.023
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.023
Rat
intracellular transportGO:00469071850.023
response to estrogenGO:00436272320.023
neurological system processGO:00508772190.023
Fly
regulation of metal ion transportGO:00109591180.023
Rat
positive regulation of cellular biosynthetic processGO:00313282950.023
Rat
regulation of catalytic activityGO:00507903040.022
Rat
negative regulation of multicellular organismal processGO:00512412030.022
protein complex assemblyGO:00064612630.022
Fly
circulatory system processGO:00030131830.022
cellular response to peptideGO:19016531330.022
Rat
localization of cellGO:00516742020.022
Rat
membrane organizationGO:0061024940.022
positive regulation of transportGO:00510502450.022
Rat
positive regulation of multicellular organismal processGO:00512403870.022
Rat
cellular cation homeostasisGO:00300031800.022
Rat
cellular catabolic processGO:00442482950.022
cellular response to biotic stimulusGO:0071216590.022
regulation of lymphocyte chemotaxisGO:190162310.022
purine nucleotide metabolic processGO:00061632290.022
cellular macromolecule localizationGO:00707271220.021
positive regulation of cell deathGO:00109421840.021
Rat
ribonucleoside monophosphate metabolic processGO:0009161880.021
nucleoside triphosphate catabolic processGO:00091431230.021
response to nutrient levelsGO:00316673700.021
Rat
learning or memoryGO:0007611900.021
Fly
purine nucleoside catabolic processGO:00061521240.021
reactive nitrogen species metabolic processGO:200105710.021
regulation of intracellular signal transductionGO:19025312180.021
Rat
positive regulation of programmed cell deathGO:00430681570.021
Rat
regulation of apoptotic processGO:00429813350.020
Rat
establishment of protein localizationGO:00451841410.020
Rat
purine nucleoside monophosphate catabolic processGO:0009128550.020
regulation of cellular protein metabolic processGO:00322682670.020
Rat
response to reactive oxygen speciesGO:00003021200.020
regulation of secretionGO:00510462240.020
Rat
response to toxic substanceGO:00096361330.020
Rat
organic substance catabolic processGO:19015753160.020
hormone secretionGO:00468791150.020
regulation of defense responseGO:0031347680.020
negative regulation of molecular functionGO:00440921330.020
secretion by cellGO:00329402480.020
receptor mediated endocytosisGO:0006898420.019
innate immune responseGO:0045087350.019
regulation of protein phosphorylationGO:00019321830.019
Rat
cytokine biosynthetic processGO:004208930.019
hematopoietic or lymphoid organ developmentGO:0048534360.019
purine ribonucleotide metabolic processGO:00091502270.019
protein localizationGO:00081041910.019
Rat
cellular component biogenesisGO:00440853680.019
Rat Fly
g protein coupled purinergic nucleotide receptor signaling pathwayGO:003558930.019
cellular ion homeostasisGO:00068731840.019
Rat
regulation of transcription dna templatedGO:00063553740.019
Rat
response to extracellular stimulusGO:00099913800.019
Rat
immunoglobulin mediated immune responseGO:001606440.019
positive regulation of cytosolic calcium ion concentrationGO:00072041220.019
Rat
positive regulation of molecular functionGO:00440932300.019
Rat
response to cytokineGO:00340972150.019
regulation of programmed cell deathGO:00430673410.019
Rat
negative regulation of transportGO:00510511360.019
purine ribonucleoside triphosphate catabolic processGO:00092071220.019
immune effector processGO:0002252530.018
cellular lipid metabolic processGO:00442552080.018
Rat
immune system developmentGO:0002520410.018
cytoplasmic transportGO:00164821150.018
Rat
positive regulation of nucleocytoplasmic transportGO:0046824170.018
positive regulation of protein modification processGO:00314011420.018
Rat
response to hypoxiaGO:00016662310.018
Rat
positive regulation of cell adhesionGO:0045785300.018
Rat
aromatic compound catabolic processGO:00194391680.018
cellular metal ion homeostasisGO:00068751720.018
Rat
regulation of cytokine productionGO:0001817560.017
Rat
central nervous system developmentGO:00074173110.017
Rat
negative regulation of macromolecule metabolic processGO:00106052600.017
Rat
response to hydrogen peroxideGO:0042542890.017
Rat
positive regulation of intracellular signal transductionGO:19025331380.017
Rat
protein complex biogenesisGO:00702712630.017
Fly
positive regulation of endothelial cell migrationGO:001059540.017
regulation of ion homeostasisGO:2000021630.017
Rat
cardiovascular system developmentGO:00723581340.017
regulation of neurogenesisGO:00507672470.017
Rat
protein transportGO:00150311320.016
Rat
response to organophosphorusGO:00466831020.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
Rat
small gtpase mediated signal transductionGO:0007264360.016
regulation of anatomical structure sizeGO:00900661350.016
Fly
blood coagulationGO:0007596260.016
regulation of multicellular organismal developmentGO:20000263760.016
Rat
regulation of cellular extravasationGO:000269120.016
single organism cellular localizationGO:19025801020.016
cellular response to red or far red lightGO:007148910.016
positive regulation of immunoglobulin mediated immune responseGO:000289120.016
positive regulation of phosphate metabolic processGO:00459372620.016
Rat
regulation of reactive oxygen species biosynthetic processGO:190342650.016
positive regulation of cell communicationGO:00106472710.015
Rat
developmental process involved in reproductionGO:00030061590.015
Fly
single organism organelle organizationGO:19025891800.015
Fly
reactive oxygen species biosynthetic processGO:190340980.015
cation transportGO:00068123820.015
rna metabolic processGO:00160704060.015
Rat
positive regulation of protein phosphorylationGO:00019341350.015
Rat
positive regulation of cell migrationGO:0030335960.015
Rat
response to bacteriumGO:00096172000.015
Rat
immune response regulating cell surface receptor signaling pathwayGO:0002768100.015
Rat
cellular response to oxidative stressGO:0034599760.015
agingGO:00075682410.015
Rat Fly
divalent inorganic cation transportGO:00725111340.015
Rat
regulation of ion transportGO:00432692450.015
Rat
alpha beta t cell activationGO:004663130.015
positive regulation of innate immune responseGO:0045089110.015
regulation of t cell chemotaxisGO:001081910.015
negative regulation of apoptotic processGO:00430661810.015
Rat
regulation of t cell migrationGO:200040410.015
protein oligomerizationGO:00512591910.014
sequestering of calcium ionGO:005120880.014
response to peptideGO:19016522920.014
Rat
apoptotic processGO:00069153810.014
Rat
positive regulation of t cell migrationGO:200040610.014
cellular response to mechanical stimulusGO:0071260480.014
response to oxygen levelsGO:00704822650.014
Rat
locomotionGO:00400112370.014
Rat
cellular response to abiotic stimulusGO:0071214850.014
signal releaseGO:00230611450.014
organic hydroxy compound metabolic processGO:19016151150.014
positive regulation of neurogenesisGO:00507691650.014
Rat
regulation of behaviorGO:0050795610.014
reproductive system developmentGO:00614581280.014
Fly
alpha beta t cell differentiationGO:004663220.014
anatomical structure morphogenesisGO:00096532980.014
Fly
regulation of catabolic processGO:00098941130.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
histamine production involved in inflammatory responseGO:000234930.014
negative regulation of signalingGO:00230571570.014
Rat
biological adhesionGO:00226101100.014
Rat
positive regulation of secretion by cellGO:19035321280.014
Rat
negative regulation of phosphorus metabolic processGO:0010563800.014
positive regulation of cellular protein metabolic processGO:00322701670.014
Rat
cellular response to insulin stimulusGO:0032869810.014
Rat
positive regulation of defense responseGO:0031349370.014
multi organism reproductive processGO:00447032620.014
Fly
hemopoiesisGO:0030097340.014
positive regulation of protein localization to nucleusGO:1900182150.013
positive regulation of phosphorylationGO:00423271770.013
Rat
regulation of cell motilityGO:20001451310.013
Rat
dna metabolic processGO:0006259960.013
Rat Fly
regulation of cytokine biosynthetic processGO:004203530.013
response to oxidative stressGO:00069791860.013
signal transduction by phosphorylationGO:00230141440.013
Rat
regulation of protein metabolic processGO:00512462890.013
Rat
positive regulation of rna biosynthetic processGO:19026801970.013
Rat
icosanoid metabolic processGO:0006690380.013
multicellular organism reproductionGO:00325042330.013
Fly
monocarboxylic acid metabolic processGO:00327871520.013
ribonucleotide metabolic processGO:00092592310.013
t cell extravasationGO:007268310.013
positive regulation of cytoplasmic transportGO:1903651320.013
negative regulation of developmental processGO:00510931250.013
single organism reproductive processGO:00447022970.013
Fly
response to purine containing compoundGO:00140741260.013
cellular response to nitrogen compoundGO:19016992100.013
Rat
negative regulation of ion transportGO:0043271510.013
cellular response to external stimulusGO:00714961180.013
Rat
regulation of membrane potentialGO:00423911100.013
regulation of dna metabolic processGO:0051052600.013
Rat
regulation of blood circulationGO:19035221100.013
regulation of system processGO:00440572080.013
Rat
regulation of transferase activityGO:00513381230.013
Rat
positive regulation of t cell chemotaxisGO:001082010.013
regulation of protein transportGO:0051223680.012
Rat
response to external biotic stimulusGO:00432072210.012
ras protein signal transductionGO:0007265290.012
positive regulation of cell projection organizationGO:00313461110.012
regulation of signal transductionGO:00099663180.012
Rat
hepaticobiliary system developmentGO:0061008900.012
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.012
ribonucleoside monophosphate catabolic processGO:0009158550.012
organ regenerationGO:00311001010.012
response to ethanolGO:00454711620.012
divalent metal ion transportGO:00708381320.012
Rat
b cell activation involved in immune responseGO:000231210.012
negative regulation of cellular protein metabolic processGO:00322691060.012
neuron deathGO:00709971270.012
Rat
negative regulation of protein metabolic processGO:00512481140.012
positive regulation of gene expressionGO:00106282440.012
Rat
regulation of nucleotide catabolic processGO:0030811650.012
cell cell signalingGO:00072673350.012
gtp catabolic processGO:0006184710.012
sensory perception of bitter tasteGO:005091340.012
defense response to gram negative bacteriumGO:005082930.012
sex differentiationGO:00075481130.012
Fly
mapk cascadeGO:00001651400.012
Rat
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
Rat
cellular response to acid chemicalGO:0071229750.012
Rat
regulation of phosphorylationGO:00423252480.012
Rat
regulation of blood vessel endothelial cell migrationGO:004353540.012
positive regulation of cellular component organizationGO:00511302000.012
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
Rat
negative regulation of cell proliferationGO:00082851190.011
macromolecular complex assemblyGO:00650032730.011
Fly
positive regulation of neuron differentiationGO:00456661260.011
sequestering of metal ionGO:005123890.011
positive regulation of protein import into nucleusGO:0042307140.011
amine transportGO:0015837570.011
gtp metabolic processGO:0046039720.011
positive regulation of cell motilityGO:2000147970.011
Rat
response to radiationGO:00093141370.011
regulation of hormone levelsGO:00108171870.011
neuron differentiationGO:00301823680.011
leukocyte differentiationGO:0002521300.011
positive regulation of protein kinase activityGO:0045860730.011
Rat
positive regulation of mapk cascadeGO:0043410920.011
Rat
regulation of mapk cascadeGO:00434081160.011
Rat
response to woundingGO:00096112540.011
Rat
cell motilityGO:00488702020.011
Rat
regulation of cellular catabolic processGO:00313291010.011
regulation of cellular component sizeGO:0032535510.011
Fly
regulation of reactive oxygen species metabolic processGO:2000377260.011
nitrogen compound transportGO:00717052290.011
cellular response to lipidGO:00713962010.011
Rat
regulation of cell developmentGO:00602842630.011
Rat
neuron developmentGO:00486662860.011
positive regulation of rna metabolic processGO:00512542030.011
Rat
regulation of rna biosynthetic processGO:20011413810.011
Rat
response to glucoseGO:00097491360.010
single organism behaviorGO:00447081300.010
Fly
response to activityGO:0014823730.010
response to monosaccharideGO:00342841590.010
positive regulation of neuron projection developmentGO:0010976990.010
reproductive structure developmentGO:00486081280.010
Fly
blood circulationGO:00080151830.010
positive regulation of intracellular protein transportGO:0090316200.010
positive regulation of map kinase activityGO:0043406460.010
Rat
regulation of leukocyte differentiationGO:1902105200.010
organelle organizationGO:00069962660.010
Fly
positive regulation of secretionGO:00510471400.010
Rat
positive regulation of angiogenesisGO:0045766280.010
regulation of anatomical structure morphogenesisGO:00226031410.010
cellular response to molecule of bacterial originGO:0071219560.010
Rat

Btk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org