IMP: Integrative Multi-species Prediction

Rattus norvegicus

85 known processes

Myh6

myosin, heavy chain 6, cardiac muscle, alpha

(Aliases: Myhca)

Ensembl: ENSRNOG00000025757
Entrez: 29556
RGD: 62029
UniProtKB: G3V885

Process Predictions
Disease Predictions

Myh6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cardiac ventricle development	GO:0003231	1	0.802	Human
cardiac chamber development	GO:0003205	1	0.740	Human
muscle contraction	GO:0006936	88	0.678
cardiac muscle contraction	GO:0060048	27	0.655
cardiac muscle tissue morphogenesis	GO:0055008	1	0.620	Human
striated muscle contraction	GO:0006941	44	0.556	Human Zebrafish Mouse
ventricular cardiac muscle cell action potential	GO:0086005	2	0.440
slow twitch skeletal muscle fiber contraction	GO:0031444	2	0.423	Zebrafish
muscle organ morphogenesis	GO:0048644	1	0.340	Human
muscle tissue morphogenesis	GO:0060415	1	0.330	Human
circulatory system development	GO:0072359	134	0.327	Human Mouse
muscle system process	GO:0003012	115	0.310
transmembrane transport	GO:0055085	412	0.308
heart contraction	GO:0060047	57	0.305	Human Mouse
actin myosin filament sliding	GO:0033275	2	0.298	Human
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.288
ion transmembrane transport	GO:0034220	365	0.269
cellular potassium ion transport	GO:0071804	72	0.260
nucleoside triphosphate catabolic process	GO:0009143	123	0.251
cellular component biogenesis	GO:0044085	368	0.247	Mouse Fly
membrane depolarization during action potential	GO:0086010	1	0.244
myosin filament assembly	GO:0031034	1	0.229	Fly
heart process	GO:0003015	57	0.216	Human Mouse
twitch skeletal muscle contraction	GO:0014721	3	0.204	Zebrafish
heart morphogenesis	GO:0003007	3	0.194	Human
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.192
nucleotide metabolic process	GO:0009117	279	0.188
purine ribonucleoside monophosphate catabolic process	GO:0009169	55	0.182
cation transport	GO:0006812	382	0.180
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.171
protein complex biogenesis	GO:0070271	263	0.170	Fly
cardiac myofibril assembly	GO:0055003	1	0.167
cation transmembrane transport	GO:0098655	263	0.165
actin filament based process	GO:0030029	86	0.164	Human Mouse Fly
nucleotide catabolic process	GO:0009166	139	0.157
carbohydrate derivative catabolic process	GO:1901136	147	0.157
nucleoside catabolic process	GO:0009164	126	0.155
macromolecular complex subunit organization	GO:0043933	339	0.151	Fly
cellular component assembly	GO:0022607	360	0.148	Mouse Fly
purine nucleotide metabolic process	GO:0006163	229	0.148
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.147
response to purine containing compound	GO:0014074	126	0.145
myosin filament organization	GO:0031033	2	0.143	Fly
purine containing compound metabolic process	GO:0072521	253	0.140
ribonucleotide metabolic process	GO:0009259	231	0.139
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.139	Mouse Fly
inorganic cation transmembrane transport	GO:0098662	202	0.138
homeostatic process	GO:0042592	331	0.138
ribonucleoside metabolic process	GO:0009119	174	0.136
nucleoside monophosphate metabolic process	GO:0009123	93	0.133
regulation of ion transport	GO:0043269	245	0.133
positive regulation of transport	GO:0051050	245	0.132
glycosyl compound metabolic process	GO:1901657	182	0.131
circulatory system process	GO:0003013	183	0.128	Human Mouse
ribonucleotide catabolic process	GO:0009261	136	0.126
purine ribonucleotide metabolic process	GO:0009150	227	0.122
regulation of muscle system process	GO:0090257	79	0.120
ribose phosphate metabolic process	GO:0019693	235	0.115
metal ion transport	GO:0030001	289	0.113
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.110
blood circulation	GO:0008015	183	0.108	Human Mouse
regulation of muscle contraction	GO:0006937	53	0.107
potassium ion transport	GO:0006813	97	0.106
anatomical structure morphogenesis	GO:0009653	298	0.105	Human Mouse Fly
regulation of actin filament based movement	GO:1903115	12	0.102
cellular component movement	GO:0006928	248	0.101	Human Mouse Fly
organophosphate metabolic process	GO:0019637	370	0.100
purine nucleoside catabolic process	GO:0006152	124	0.098
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.097
anion transport	GO:0006820	178	0.096
nucleoside triphosphate metabolic process	GO:0009141	144	0.096
response to hypoxia	GO:0001666	231	0.095
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	GO:0014808	4	0.094
atp catabolic process	GO:0006200	54	0.094
carbohydrate derivative metabolic process	GO:1901135	346	0.094
organophosphate catabolic process	GO:0046434	148	0.093
tissue morphogenesis	GO:0048729	22	0.091	Human
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.090
potassium ion transmembrane transport	GO:0071805	71	0.090
cell projection organization	GO:0030030	302	0.088
muscle structure development	GO:0061061	87	0.086	Human Mouse Fly
cardiovascular system development	GO:0072358	134	0.086	Human Mouse
cellular protein complex assembly	GO:0043623	44	0.082	Fly
aromatic compound catabolic process	GO:0019439	168	0.081
response to extracellular stimulus	GO:0009991	380	0.080
regulation of striated muscle contraction	GO:0006942	21	0.078
regulation of multicellular organismal development	GO:2000026	376	0.078	Mouse
regulation of molecular function	GO:0065009	398	0.077	Mouse
ribonucleoside monophosphate catabolic process	GO:0009158	55	0.076
regulation of actin filament based process	GO:0032970	42	0.075
protein complex subunit organization	GO:0071822	302	0.074	Fly
sarcomere organization	GO:0045214	6	0.074	Mouse Fly
chemical homeostasis	GO:0048878	292	0.074
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.074
nitrogen compound transport	GO:0071705	229	0.072
cellular component morphogenesis	GO:0032989	155	0.071	Mouse Fly
regulation of system process	GO:0044057	208	0.071	Human Mouse
cardiac muscle tissue development	GO:0048738	26	0.068	Human Mouse
monovalent inorganic cation transport	GO:0015672	172	0.066
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.066
nucleoside metabolic process	GO:0009116	179	0.066
purine ribonucleoside catabolic process	GO:0046130	124	0.066
purine nucleotide catabolic process	GO:0006195	136	0.065
cardiac muscle cell contraction	GO:0086003	10	0.065
organic acid transport	GO:0015849	116	0.063
nucleoside phosphate catabolic process	GO:1901292	140	0.062
purine nucleoside metabolic process	GO:0042278	169	0.062
apoptotic process	GO:0006915	381	0.060
carboxylic acid transport	GO:0046942	115	0.058
cellular macromolecule localization	GO:0070727	122	0.057
organelle organization	GO:0006996	266	0.057	Mouse Fly
actin filament based movement	GO:0030048	16	0.057	Human Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.057
tissue development	GO:0009888	252	0.055	Human Mouse Fly
cardiac muscle cell action potential involved in contraction	GO:0086002	2	0.054
cellular response to endogenous stimulus	GO:0071495	377	0.054
cellular protein localization	GO:0034613	122	0.052
cytoskeleton organization	GO:0007010	111	0.052	Mouse Fly
nucleoside phosphate metabolic process	GO:0006753	283	0.052
response to reactive oxygen species	GO:0000302	120	0.051	Rat
divalent inorganic cation homeostasis	GO:0072507	165	0.050
response to decreased oxygen levels	GO:0036293	237	0.049
regulation of blood circulation	GO:1903522	110	0.049	Human Mouse
regulation of transmembrane transporter activity	GO:0022898	49	0.049
inorganic ion transmembrane transport	GO:0098660	229	0.048
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.047
regulation of potassium ion transport	GO:0043266	29	0.047
macromolecule localization	GO:0033036	252	0.046
cellular homeostasis	GO:0019725	252	0.046
regulation of heart rate	GO:0002027	16	0.046	Human Mouse
striated muscle tissue development	GO:0014706	58	0.046	Human Mouse
purine containing compound catabolic process	GO:0072523	138	0.046
regulation of catalytic activity	GO:0050790	304	0.045	Mouse
regulation of cardiac muscle cell contraction	GO:0086004	11	0.045
cellular calcium ion homeostasis	GO:0006874	160	0.044
heart development	GO:0007507	72	0.044	Human Mouse
cell cell signaling	GO:0007267	335	0.043
positive regulation of ion transport	GO:0043270	94	0.043
heterocycle catabolic process	GO:0046700	167	0.042
cellular nitrogen compound catabolic process	GO:0044270	163	0.041
response to nutrient levels	GO:0031667	370	0.041
response to oxygen levels	GO:0070482	265	0.041
regulation of cardiac muscle contraction	GO:0055117	17	0.040
regulation of secretion	GO:0051046	224	0.040
nucleoside monophosphate catabolic process	GO:0009125	56	0.040
negative regulation of cellular metabolic process	GO:0031324	281	0.039
regulation of cytoskeleton organization	GO:0051493	49	0.039
regulation of cardiac muscle contraction by calcium ion signaling	GO:0010882	3	0.039
nucleobase containing small molecule metabolic process	GO:0055086	316	0.039
glycosyl compound catabolic process	GO:1901658	126	0.039
calcium ion homeostasis	GO:0055074	162	0.039
response to camp	GO:0051591	91	0.039
regulation of ion homeostasis	GO:2000021	63	0.038
locomotion	GO:0040011	237	0.038	Fly
response to corticosteroid	GO:0031960	235	0.038
cardiocyte differentiation	GO:0035051	22	0.037	Mouse
response to oxidative stress	GO:0006979	186	0.037	Rat
metal ion homeostasis	GO:0055065	186	0.037
cardiac muscle cell action potential	GO:0086001	5	0.036
intracellular signal transduction	GO:0035556	314	0.036
regulation of dendritic spine morphogenesis	GO:0061001	6	0.036
regulation of homeostatic process	GO:0032844	101	0.036
cellular response to mechanical stimulus	GO:0071260	48	0.036
cation homeostasis	GO:0055080	195	0.036
positive regulation of molecular function	GO:0044093	230	0.035
regulation of cellular component organization	GO:0051128	368	0.035
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.035
regulation of hormone levels	GO:0010817	187	0.035
response to ketone	GO:1901654	182	0.035
organelle assembly	GO:0070925	22	0.034	Mouse Fly
organ morphogenesis	GO:0009887	75	0.034	Human
response to metal ion	GO:0010038	253	0.034
sequestering of metal ion	GO:0051238	9	0.034
membrane depolarization during cardiac muscle cell action potential	GO:0086012	1	0.034
regulation of membrane potential	GO:0042391	110	0.034
muscle tissue development	GO:0060537	58	0.034	Human Mouse
purine ribonucleoside metabolic process	GO:0046128	168	0.034
brain development	GO:0007420	247	0.034
purine ribonucleotide catabolic process	GO:0009154	136	0.033
ribonucleoside catabolic process	GO:0042454	126	0.033
purine ribonucleotide biosynthetic process	GO:0009152	81	0.033
cellular response to stress	GO:0033554	269	0.033
l glutamate import	GO:0051938	2	0.033
response to growth factor	GO:0070848	189	0.033
regulation of purine nucleotide metabolic process	GO:1900542	115	0.033	Mouse
cellular response to alkaloid	GO:0071312	25	0.032
organonitrogen compound biosynthetic process	GO:1901566	167	0.032
response to peptide hormone	GO:0043434	278	0.032
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.031
secretion	GO:0046903	307	0.031
negative regulation of response to stimulus	GO:0048585	155	0.031
regulation of blood pressure	GO:0008217	83	0.030	Mouse
macromolecular complex assembly	GO:0065003	273	0.030	Fly
microtubule polymerization or depolymerization	GO:0031109	13	0.030
regulation of transporter activity	GO:0032409	50	0.030
response to glucocorticoid	GO:0051384	223	0.029
single organism organelle organization	GO:1902589	180	0.029	Mouse Fly
cellular macromolecular complex assembly	GO:0034622	58	0.029	Fly
multicellular organismal movement	GO:0050879	17	0.029	Zebrafish
cellular chemical homeostasis	GO:0055082	247	0.029
striated muscle cell development	GO:0055002	26	0.028	Mouse Fly
regulation of phosphorylation	GO:0042325	248	0.027
organic anion transport	GO:0015711	132	0.027
atp metabolic process	GO:0046034	72	0.027
negative regulation of cell communication	GO:0010648	158	0.027
action potential	GO:0001508	54	0.027
organonitrogen compound catabolic process	GO:1901565	179	0.027
divalent metal ion transport	GO:0070838	132	0.027
pyruvate metabolic process	GO:0006090	27	0.026
musculoskeletal movement	GO:0050881	17	0.026	Zebrafish
regulation of sodium ion transmembrane transporter activity	GO:2000649	4	0.026
carbohydrate derivative biosynthetic process	GO:1901137	124	0.026
response to organophosphorus	GO:0046683	102	0.026
endoplasmic reticulum to cytosol transport	GO:1903513	4	0.026
cellular ion homeostasis	GO:0006873	184	0.026
neurological system process	GO:0050877	219	0.026
multi organism reproductive process	GO:0044703	262	0.026	Fly
intracellular transport	GO:0046907	185	0.026
programmed cell death	GO:0012501	392	0.026
cellular component assembly involved in morphogenesis	GO:0010927	17	0.025	Mouse Fly
positive regulation of cellular component organization	GO:0051130	200	0.025
response to temperature stimulus	GO:0009266	94	0.025
regulation of nucleic acid templated transcription	GO:1903506	380	0.025	Mouse
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.025
cellular response to growth factor stimulus	GO:0071363	162	0.025
response to electrical stimulus involved in regulation of muscle adaptation	GO:0014878	4	0.025
ribose phosphate biosynthetic process	GO:0046390	87	0.025
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.024
cytosolic calcium ion homeostasis	GO:0051480	140	0.024
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.024
organic cyclic compound catabolic process	GO:1901361	175	0.024
regulation of catabolic process	GO:0009894	113	0.024	Mouse
positive regulation of ion transmembrane transport	GO:0034767	24	0.023
protein complex assembly	GO:0006461	263	0.023	Fly
regulation of ion transmembrane transporter activity	GO:0032412	48	0.023
purine nucleotide biosynthetic process	GO:0006164	83	0.023
positive regulation of potassium ion transmembrane transport	GO:1901381	4	0.023
cellular response to nitrogen compound	GO:1901699	210	0.023
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.023
membrane hyperpolarization	GO:0060081	11	0.023
protein homooligomerization	GO:0051260	91	0.023
positive regulation of multicellular organismal process	GO:0051240	387	0.023
muscle cell differentiation	GO:0042692	52	0.022	Mouse Fly
cardiac conduction	GO:0061337	2	0.022
positive regulation of cytoskeleton organization	GO:0051495	26	0.022
positive regulation of catalytic activity	GO:0043085	184	0.022
negative regulation of macromolecule metabolic process	GO:0010605	260	0.022
single organism biosynthetic process	GO:0044711	342	0.022
cellular catabolic process	GO:0044248	295	0.022
head development	GO:0060322	247	0.022
actomyosin structure organization	GO:0031032	22	0.022	Mouse Fly
actin cytoskeleton organization	GO:0030036	73	0.022	Mouse Fly
regulation of purine nucleotide catabolic process	GO:0033121	65	0.021	Mouse
maintenance of location	GO:0051235	17	0.021
negative regulation of cellular biosynthetic process	GO:0031327	161	0.021
response to blue light	GO:0009637	1	0.021
nucleoside phosphate biosynthetic process	GO:1901293	102	0.021
purine containing compound biosynthetic process	GO:0072522	85	0.021
negative regulation of apoptotic process	GO:0043066	181	0.020
regulation of cell development	GO:0060284	263	0.020
nucleotide biosynthetic process	GO:0009165	98	0.020
transcription from rna polymerase ii promoter	GO:0006366	252	0.020	Mouse
proteolysis	GO:0006508	175	0.020
defense response	GO:0006952	194	0.020
limbic system development	GO:0021761	38	0.020
cellular response to abiotic stimulus	GO:0071214	85	0.020
regulation of neurogenesis	GO:0050767	247	0.020
regulation of phosphorus metabolic process	GO:0051174	349	0.019	Mouse
negative regulation of gene expression	GO:0010629	199	0.019
sequestering of calcium ion	GO:0051208	8	0.019
positive regulation of phosphorus metabolic process	GO:0010562	262	0.019
organophosphate biosynthetic process	GO:0090407	143	0.019
nucleic acid templated transcription	GO:0097659	379	0.019	Mouse
positive regulation of ion transmembrane transporter activity	GO:0032414	13	0.019
response to carbohydrate	GO:0009743	183	0.019
erythrocyte differentiation	GO:0030218	1	0.019
neuron projection development	GO:0031175	273	0.018
single organism intracellular transport	GO:1902582	166	0.018
catabolic process	GO:0009056	351	0.018
multi multicellular organism process	GO:0044706	138	0.018
positive regulation of biosynthetic process	GO:0009891	319	0.018
regeneration	GO:0031099	163	0.018
response to wounding	GO:0009611	254	0.018
lipid transport	GO:0006869	61	0.018
response to insulin	GO:0032868	133	0.018
positive regulation of rna biosynthetic process	GO:1902680	197	0.018
regulation of rna metabolic process	GO:0051252	391	0.018	Mouse
neuron differentiation	GO:0030182	368	0.018
carboxylic acid metabolic process	GO:0019752	289	0.018
lipid metabolic process	GO:0006629	283	0.018
negative regulation of metabolic process	GO:0009892	331	0.017
response to calcium ion	GO:0051592	59	0.017
amine metabolic process	GO:0009308	38	0.017
positive regulation of transmembrane transport	GO:0034764	25	0.017
membrane repolarization	GO:0086009	1	0.017
bmp signaling pathway	GO:0030509	4	0.017	Mouse
response to peptide	GO:1901652	292	0.017
actin mediated cell contraction	GO:0070252	12	0.017	Human
single organism catabolic process	GO:0044712	283	0.016
response to tumor necrosis factor	GO:0034612	56	0.016
organic hydroxy compound transport	GO:0015850	77	0.016
axis specification	GO:0009798	4	0.016
negative regulation of molecular function	GO:0044092	133	0.016
organic acid metabolic process	GO:0006082	292	0.016
locomotor rhythm	GO:0045475	1	0.016
cellular response to organic cyclic compound	GO:0071407	202	0.016
response to alkaloid	GO:0043279	132	0.016
cyclic purine nucleotide metabolic process	GO:0052652	62	0.016
central nervous system development	GO:0007417	311	0.016
monocarboxylic acid transport	GO:0015718	52	0.016
regulation of microtubule polymerization or depolymerization	GO:0031110	12	0.016
embryo development	GO:0009790	49	0.016	Mouse
response to follicle stimulating hormone	GO:0032354	18	0.015
calcium ion transport from endoplasmic reticulum to cytosol	GO:1903514	4	0.015
cellular amine metabolic process	GO:0044106	38	0.015
regulation of apoptotic process	GO:0042981	335	0.015
rhythmic process	GO:0048511	156	0.015
response to inorganic substance	GO:0010035	377	0.015
positive regulation of microtubule polymerization or depolymerization	GO:0031112	7	0.015
regulation of membrane repolarization	GO:0060306	1	0.015
regulation of heart contraction	GO:0008016	48	0.015	Human Mouse
microtubule based process	GO:0007017	36	0.015
sensory perception of light stimulus	GO:0050953	3	0.015
cellular response to cytokine stimulus	GO:0071345	127	0.015
regulation of blood vessel size	GO:0050880	89	0.015
skeletal muscle contraction	GO:0003009	17	0.015	Zebrafish
muscle organ development	GO:0007517	50	0.015	Human Mouse Fly
cellular response to organonitrogen compound	GO:0071417	197	0.015
regulation of phosphate metabolic process	GO:0019220	349	0.015	Mouse
regulation of nucleotide metabolic process	GO:0006140	117	0.015	Mouse
protein localization to membrane	GO:0072657	36	0.015
nucleobase containing compound catabolic process	GO:0034655	152	0.015
response to starvation	GO:0042594	59	0.015
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.015
regulation of nucleoside metabolic process	GO:0009118	66	0.015	Mouse
oxoacid metabolic process	GO:0043436	290	0.014
positive regulation of calcium ion transport	GO:0051928	36	0.014
positive regulation of transporter activity	GO:0032411	14	0.014
regulation of calcium ion transport	GO:0051924	77	0.014
vasculature development	GO:0001944	70	0.014
adult locomotory behavior	GO:0008344	4	0.014
response to radiation	GO:0009314	137	0.014
negative regulation of programmed cell death	GO:0043069	183	0.014
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	GO:0010880	4	0.014
muscle cell development	GO:0055001	26	0.014	Mouse Fly
rna metabolic process	GO:0016070	406	0.014	Mouse
positive regulation of phosphate metabolic process	GO:0045937	262	0.014
secretion by cell	GO:0032940	248	0.014
positive regulation of nucleotide metabolic process	GO:0045981	91	0.014
regulation of cellular localization	GO:0060341	263	0.014
cytoplasmic transport	GO:0016482	115	0.013
organic substance catabolic process	GO:1901575	316	0.013
multicellular organismal signaling	GO:0035637	44	0.013
sodium ion transport	GO:0006814	82	0.013
positive regulation of long term synaptic potentiation	GO:1900273	4	0.013
response to transition metal nanoparticle	GO:1990267	122	0.013
positive regulation of response to stimulus	GO:0048584	285	0.013
cellular response to external stimulus	GO:0071496	118	0.013
negative regulation of cell death	GO:0060548	229	0.013
regulation of neuron differentiation	GO:0045664	208	0.013
regulation of peptide hormone secretion	GO:0090276	80	0.013
regulation of ion transmembrane transport	GO:0034765	121	0.013
synaptic transmission	GO:0007268	235	0.013
reproduction	GO:0000003	245	0.013	Fly
actin filament organization	GO:0007015	42	0.013	Fly
choline transport	GO:0015871	4	0.013
cellular metal ion homeostasis	GO:0006875	172	0.013
regulation of neuron projection development	GO:0010975	161	0.013
cell projection morphogenesis	GO:0048858	123	0.013
organic hydroxy compound metabolic process	GO:1901615	115	0.013
divalent inorganic cation transport	GO:0072511	134	0.013
protein oligomerization	GO:0051259	191	0.013
rhythmic behavior	GO:0007622	24	0.013
reproductive process	GO:0022414	372	0.013	Fly
response to nicotine	GO:0035094	51	0.013
peptide transport	GO:0015833	97	0.013
response to acid chemical	GO:0001101	222	0.013
cellular lipid metabolic process	GO:0044255	208	0.013
single organism behavior	GO:0044708	130	0.012
regulation of tube size	GO:0035150	89	0.012
response to hexose	GO:0009746	144	0.012
regulation of cellular component movement	GO:0051270	150	0.012
negative regulation of signal transduction	GO:0009968	83	0.012
amino acid transport	GO:0006865	70	0.012
mapk cascade	GO:0000165	140	0.012
regulation of cell proliferation	GO:0042127	359	0.012
cellular cation homeostasis	GO:0030003	180	0.012
response to mechanical stimulus	GO:0009612	134	0.012
cellular response to camp	GO:0071320	26	0.012
regulation of programmed cell death	GO:0043067	341	0.012
regulation of hydrolase activity	GO:0051336	143	0.012	Mouse
gtp metabolic process	GO:0046039	72	0.012
regulation of cellular amine metabolic process	GO:0033238	8	0.012
negative regulation of potassium ion transmembrane transport	GO:1901380	3	0.012
regulation of cellular component biogenesis	GO:0044087	86	0.012
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.012
cellular response to insulin stimulus	GO:0032869	81	0.011
peptide hormone secretion	GO:0030072	84	0.011
protein phosphorylation	GO:0006468	345	0.011
myoblast fusion	GO:0007520	2	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.011
ribonucleotide biosynthetic process	GO:0009260	85	0.011
regulation of cellular catabolic process	GO:0031329	101	0.011	Mouse
inflammatory response	GO:0006954	150	0.011
regulation of metal ion transport	GO:0010959	118	0.011
regulation of mapk cascade	GO:0043408	116	0.011
spindle organization	GO:0007051	2	0.011
optic nerve development	GO:0021554	3	0.011
cgmp biosynthetic process	GO:0006182	15	0.011
regulation of organelle organization	GO:0033043	80	0.011
carbohydrate homeostasis	GO:0033500	75	0.011
negative regulation of cell proliferation	GO:0008285	119	0.011
establishment of planar polarity	GO:0001736	1	0.011
cytosolic calcium ion transport	GO:0060401	39	0.011
signal transduction by phosphorylation	GO:0023014	144	0.011
male gamete generation	GO:0048232	99	0.011
neural crest cell differentiation	GO:0014033	2	0.011
negative regulation of transcription dna templated	GO:0045892	116	0.011
metanephric comma shaped body morphogenesis	GO:0072278	2	0.011
response to estradiol	GO:0032355	164	0.011
alcohol metabolic process	GO:0006066	77	0.011
regulation of secretion by cell	GO:1903530	208	0.011
regulation of signal transduction	GO:0009966	318	0.010
establishment of anatomical structure orientation	GO:0048560	1	0.010
regulation of microtubule based process	GO:0032886	14	0.010
regulation of skeletal muscle tissue regeneration	GO:0043416	2	0.010
ossification	GO:0001503	70	0.010
positive regulation of organelle organization	GO:0010638	48	0.010
response to heat	GO:0009408	60	0.010
c21 steroid hormone biosynthetic process	GO:0006700	10	0.010
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.010
protein heterooligomerization	GO:0051291	89	0.010
response to other organism	GO:0051707	220	0.010
positive regulation of cellular amine metabolic process	GO:0033240	3	0.010
cellular response to oxygen containing compound	GO:1901701	386	0.010
small gtpase mediated signal transduction	GO:0007264	36	0.010
regulation of cellular amino acid metabolic process	GO:0006521	2	0.010
response to estrogen	GO:0043627	232	0.010
cell morphogenesis	GO:0000902	142	0.010
positive regulation of sodium ion transmembrane transporter activity	GO:2000651	1	0.010
cellular response to peptide hormone stimulus	GO:0071375	120	0.010
syncytium formation	GO:0006949	4	0.010
ion homeostasis	GO:0050801	212	0.010

Myh6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability	Func Analog Org
intrinsic cardiomyopathy	DOID:0060036	0.991	Human
cardiovascular system disease	DOID:1287	0.991	Human
disease of anatomical entity	DOID:7	0.991	Human
heart disease	DOID:114	0.991	Human
muscular disease	DOID:0080000	0.991	Human
musculoskeletal system disease	DOID:17	0.991	Human
muscle tissue disease	DOID:66	0.991	Human
cardiomyopathy	DOID:0050700	0.991	Human
myopathy	DOID:423	0.991	Human
dilated cardiomyopathy	DOID:12930	0.946	Human
muscular dystrophy	DOID:9884	0.233
long qt syndrome	DOID:2843	0.106
hypertrophic cardiomyopathy	DOID:11984	0.074	Human
sensory system disease	DOID:0050155	0.032
nervous system disease	DOID:863	0.032
eye disease	DOID:5614	0.032
eye and adnexa disease	DOID:1492	0.032
retinal disease	DOID:5679	0.032
retinitis pigmentosa	DOID:10584	0.032
retinal degeneration	DOID:8466	0.032
arrhythmogenic right ventricular cardiomyopathy	DOID:0050431	0.031
congenital heart disease	DOID:1682	0.024	Human
heart septal defect	DOID:1681	0.024	Human
inherited metabolic disorder	DOID:655	0.021
disease of metabolism	DOID:0014667	0.021
heart conduction disease	DOID:10273	0.013	Human
neuropathy	DOID:870	0.012
neuromuscular disease	DOID:440	0.012

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