IMP: Integrative Multi-species Prediction

Rattus norvegicus

37 known processes

Gcdh

glutaryl-Coenzyme A dehydrogenase

Entrez: 364975
RGD: 1308829
Ensembl: ENSRNOG00000003307
UniProtKB: D3ZT90

Process Predictions
Disease Predictions

Gcdh biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
carboxylic acid catabolic process	GO:0046395	49	0.851
cellular amino acid catabolic process	GO:0009063	21	0.801
organic acid catabolic process	GO:0016054	49	0.713
organic acid metabolic process	GO:0006082	292	0.675
branched chain amino acid metabolic process	GO:0009081	4	0.519
branched chain amino acid catabolic process	GO:0009083	4	0.469
alpha amino acid catabolic process	GO:1901606	20	0.414
oxoacid metabolic process	GO:0043436	290	0.387
small molecule catabolic process	GO:0044282	59	0.376
alpha amino acid metabolic process	GO:1901605	71	0.313
carboxylic acid metabolic process	GO:0019752	289	0.295
catabolic process	GO:0009056	351	0.283
fatty acid oxidation	GO:0019395	29	0.236
organic substance catabolic process	GO:1901575	316	0.201
single organism catabolic process	GO:0044712	283	0.199
cellular amino acid metabolic process	GO:0006520	107	0.169
organonitrogen compound catabolic process	GO:1901565	179	0.152
cofactor metabolic process	GO:0051186	95	0.121
monocarboxylic acid catabolic process	GO:0072329	28	0.119
protein tetramerization	GO:0051262	38	0.115
protein complex assembly	GO:0006461	263	0.092
nucleobase containing small molecule metabolic process	GO:0055086	316	0.087
fatty acid beta oxidation	GO:0006635	22	0.080
lipid modification	GO:0030258	52	0.073
cellular ketone metabolic process	GO:0042180	51	0.070
valine metabolic process	GO:0006573	1	0.064
coenzyme metabolic process	GO:0006732	86	0.064
type b pancreatic cell proliferation	GO:0044342	3	0.058
protein homooligomerization	GO:0051260	91	0.057
protein oligomerization	GO:0051259	191	0.055
positive regulation of multicellular organismal process	GO:0051240	387	0.054
alcohol metabolic process	GO:0006066	77	0.054
macromolecular complex assembly	GO:0065003	273	0.052
cellular component assembly	GO:0022607	360	0.047
protein homotetramerization	GO:0051289	25	0.046
oxidation reduction process	GO:0055114	304	0.045
cellular catabolic process	GO:0044248	295	0.044
cellular lipid catabolic process	GO:0044242	37	0.043
carbohydrate derivative metabolic process	GO:1901135	346	0.042
glycosyl compound metabolic process	GO:1901657	182	0.040
cellular component biogenesis	GO:0044085	368	0.040
fatty acid catabolic process	GO:0009062	26	0.036
response to nutrient levels	GO:0031667	370	0.035
monocarboxylic acid metabolic process	GO:0032787	152	0.035
organic cyclic compound catabolic process	GO:1901361	175	0.035
positive regulation of biosynthetic process	GO:0009891	319	0.032
purine ribonucleoside metabolic process	GO:0046128	168	0.032
ribonucleoside metabolic process	GO:0009119	174	0.031
kidney development	GO:0001822	67	0.029
macromolecular complex subunit organization	GO:0043933	339	0.029
cellular amine metabolic process	GO:0044106	38	0.029
purine containing compound metabolic process	GO:0072521	253	0.028
cellular hormone metabolic process	GO:0034754	49	0.028
regulation of cellular amino acid metabolic process	GO:0006521	2	0.028
beta alanine metabolic process	GO:0019482	3	0.026
nucleoside metabolic process	GO:0009116	179	0.025
cation homeostasis	GO:0055080	195	0.024
retinal metabolic process	GO:0042574	3	0.024
lipid oxidation	GO:0034440	30	0.024
lipid metabolic process	GO:0006629	283	0.024
cellular cation homeostasis	GO:0030003	180	0.024
hepaticobiliary system development	GO:0061008	90	0.024
protein complex biogenesis	GO:0070271	263	0.023
dicarboxylic acid metabolic process	GO:0043648	42	0.023
gland development	GO:0048732	155	0.023
amine metabolic process	GO:0009308	38	0.022
regulation of cellular ketone metabolic process	GO:0010565	27	0.022
negative regulation of cell death	GO:0060548	229	0.022
protein complex subunit organization	GO:0071822	302	0.021
regulation of rna biosynthetic process	GO:2001141	381	0.021
rna metabolic process	GO:0016070	406	0.020
cellular response to oxygen containing compound	GO:1901701	386	0.020
muscle system process	GO:0003012	115	0.020
purine nucleoside metabolic process	GO:0042278	169	0.020
lipid catabolic process	GO:0016042	46	0.019
skeletal system development	GO:0001501	41	0.019
pyrimidine nucleobase catabolic process	GO:0006208	3	0.019
ncrna processing	GO:0034470	3	0.018
liver development	GO:0001889	90	0.018
leukocyte activation	GO:0045321	76	0.018
fatty acid metabolic process	GO:0006631	99	0.018
cellular homeostasis	GO:0019725	252	0.018
ion homeostasis	GO:0050801	212	0.017
brain development	GO:0007420	247	0.017
chemical homeostasis	GO:0048878	292	0.017
nucleic acid templated transcription	GO:0097659	379	0.017
response to extracellular stimulus	GO:0009991	380	0.017
protein phosphorylation	GO:0006468	345	0.017
response to inorganic substance	GO:0010035	377	0.016
single organism reproductive process	GO:0044702	297	0.016
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.016
regulation of immune system process	GO:0002682	123	0.016
positive regulation of cellular amine metabolic process	GO:0033240	3	0.016
neuron differentiation	GO:0030182	368	0.016
negative regulation of programmed cell death	GO:0043069	183	0.015
urogenital system development	GO:0001655	78	0.015
response to nutrient	GO:0007584	248	0.015
regulation of rna metabolic process	GO:0051252	391	0.015
carboxylic acid biosynthetic process	GO:0046394	83	0.015
cellular chemical homeostasis	GO:0055082	247	0.015
tissue development	GO:0009888	252	0.014
terpenoid metabolic process	GO:0006721	37	0.014
organophosphate metabolic process	GO:0019637	370	0.014
heterocycle catabolic process	GO:0046700	167	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
negative regulation of macromolecule metabolic process	GO:0010605	260	0.013
multicellular organism growth	GO:0035264	1	0.013
multicellular organismal reproductive process	GO:0048609	233	0.013
homeostatic process	GO:0042592	331	0.013
hormone metabolic process	GO:0042445	69	0.013
regulation of system process	GO:0044057	208	0.013
organelle organization	GO:0006996	266	0.013
positive regulation of triglyceride biosynthetic process	GO:0010867	4	0.013
cellular biogenic amine catabolic process	GO:0042402	9	0.013
central nervous system development	GO:0007417	311	0.013
thymine metabolic process	GO:0019859	2	0.013
thioester metabolic process	GO:0035383	28	0.013
neurological system process	GO:0050877	219	0.012
purine nucleotide metabolic process	GO:0006163	229	0.012
response to peptide hormone	GO:0043434	278	0.012
connective tissue development	GO:0061448	33	0.012
response to metal ion	GO:0010038	253	0.012
circadian regulation of gene expression	GO:0032922	3	0.012
positive regulation of cell development	GO:0010720	176	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
reactive nitrogen species metabolic process	GO:2001057	1	0.012
heart morphogenesis	GO:0003007	3	0.012
cell activation	GO:0001775	97	0.012
regulation of neurogenesis	GO:0050767	247	0.012
steroid metabolic process	GO:0008202	73	0.012
mitochondrial rna metabolic process	GO:0000959	1	0.012
progesterone biosynthetic process	GO:0006701	3	0.012
cellular metal ion homeostasis	GO:0006875	172	0.012
male gamete generation	GO:0048232	99	0.012
regulation of transcription dna templated	GO:0006355	374	0.011
head development	GO:0060322	247	0.011
metal ion homeostasis	GO:0055065	186	0.011
amine catabolic process	GO:0009310	9	0.011
regulation of cellular amine metabolic process	GO:0033238	8	0.011
ribonucleotide metabolic process	GO:0009259	231	0.011
regulation of nucleic acid templated transcription	GO:1903506	380	0.011
gamete generation	GO:0007276	124	0.011
programmed cell death	GO:0012501	392	0.011
negative regulation of cellular biosynthetic process	GO:0031327	161	0.011
immune system process	GO:0002376	204	0.011
response to aluminum ion	GO:0010044	10	0.011
positive regulation of cellular biosynthetic process	GO:0031328	295	0.011
cellular ion homeostasis	GO:0006873	184	0.011
multicellular organism reproduction	GO:0032504	233	0.011
positive regulation of lymphocyte proliferation	GO:0050671	20	0.011
tricarboxylic acid metabolic process	GO:0072350	10	0.010
positive regulation of immune system process	GO:0002684	90	0.010
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.010
forebrain development	GO:0030900	98	0.010
rhythmic process	GO:0048511	156	0.010
regulation of secretion by cell	GO:1903530	208	0.010
protein localization	GO:0008104	191	0.010

Gcdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.485
amino acid metabolic disorder	DOID:9252	0.485
disease of metabolism	DOID:0014667	0.485
organic acidemia	DOID:0060159	0.180
carbohydrate metabolic disorder	DOID:2978	0.072
disease of cellular proliferation	DOID:14566	0.011
organ system cancer	DOID:0050686	0.011
cancer	DOID:162	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network