IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Rabep1

rabaptin, RAB GTPase binding effector protein 1

Entrez: 54190
Ensembl: ENSRNOG00000005015
RGD: 708568
UniProtKB: O35550

Process Predictions
Disease Predictions

Rabep1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
multicellular organismal signaling	GO:0035637	44	0.189
neurological system process	GO:0050877	219	0.160
cellular component assembly	GO:0022607	360	0.147
axon ensheathment	GO:0008366	40	0.137
neuronal action potential	GO:0019228	35	0.134
myelination	GO:0042552	39	0.133
transmission of nerve impulse	GO:0019226	42	0.129
catabolic process	GO:0009056	351	0.119
regulation of cellular component organization	GO:0051128	368	0.107
action potential	GO:0001508	54	0.080
cell morphogenesis involved in differentiation	GO:0000904	119	0.079
macromolecule localization	GO:0033036	252	0.078
intracellular signal transduction	GO:0035556	314	0.078
macromolecular complex assembly	GO:0065003	273	0.073
protein complex assembly	GO:0006461	263	0.063
ensheathment of neurons	GO:0007272	40	0.062
regulation of membrane potential	GO:0042391	110	0.061
negative regulation of nervous system development	GO:0051961	79	0.057
amine metabolic process	GO:0009308	38	0.057
regulation of programmed cell death	GO:0043067	341	0.057
regulation of cellular localization	GO:0060341	263	0.055
regulation of signal transduction	GO:0009966	318	0.055
vesicle mediated transport	GO:0016192	181	0.052
nucleotide catabolic process	GO:0009166	139	0.052
cellular component biogenesis	GO:0044085	368	0.051
cellular amine metabolic process	GO:0044106	38	0.050
secretion	GO:0046903	307	0.050
neuron development	GO:0048666	286	0.049
macromolecular complex subunit organization	GO:0043933	339	0.049
regulation of ion transport	GO:0043269	245	0.049
secretion by cell	GO:0032940	248	0.047
organophosphate metabolic process	GO:0019637	370	0.046
negative regulation of cellular metabolic process	GO:0031324	281	0.045
organelle organization	GO:0006996	266	0.045
organic hydroxy compound metabolic process	GO:1901615	115	0.045
multi organism reproductive process	GO:0044703	262	0.045
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.044
growth	GO:0040007	165	0.044
regulation of phosphate metabolic process	GO:0019220	349	0.043
glycosyl compound catabolic process	GO:1901658	126	0.043
protein localization	GO:0008104	191	0.042
purine nucleotide metabolic process	GO:0006163	229	0.042
regulation of locomotion	GO:0040012	148	0.042
regulation of secretion	GO:0051046	224	0.042
regulation of neurogenesis	GO:0050767	247	0.041
purine containing compound metabolic process	GO:0072521	253	0.041
neuron differentiation	GO:0030182	368	0.041
regulation of phosphorus metabolic process	GO:0051174	349	0.040
nitrogen compound transport	GO:0071705	229	0.039
purine ribonucleotide metabolic process	GO:0009150	227	0.039
negative regulation of multicellular organismal process	GO:0051241	203	0.038
protein complex biogenesis	GO:0070271	263	0.038
single organism cellular localization	GO:1902580	102	0.037
response to aluminum ion	GO:0010044	10	0.037
cellular component movement	GO:0006928	248	0.037
nucleic acid templated transcription	GO:0097659	379	0.035
developmental growth	GO:0048589	100	0.035
negative regulation of mitotic cell cycle phase transition	GO:1901991	3	0.035
cation transport	GO:0006812	382	0.034
regulation of molecular function	GO:0065009	398	0.034
regulation of hydrolase activity	GO:0051336	143	0.034
response to interleukin 15	GO:0070672	4	0.034
establishment of protein localization	GO:0045184	141	0.033
regulation of cellular amine metabolic process	GO:0033238	8	0.033
positive regulation of phosphate metabolic process	GO:0045937	262	0.033
ribonucleotide metabolic process	GO:0009259	231	0.033
regulation of catalytic activity	GO:0050790	304	0.032
nucleotide metabolic process	GO:0009117	279	0.032
carbohydrate derivative catabolic process	GO:1901136	147	0.032
aromatic compound catabolic process	GO:0019439	168	0.032
regulation of secretion by cell	GO:1903530	208	0.032
cellular catabolic process	GO:0044248	295	0.031
single organism biosynthetic process	GO:0044711	342	0.031
negative regulation of cell differentiation	GO:0045596	99	0.031
reproductive process	GO:0022414	372	0.031
response to corticosteroid	GO:0031960	235	0.030
axonogenesis	GO:0007409	71	0.030
multicellular organismal reproductive process	GO:0048609	233	0.030
positive regulation of nucleoside metabolic process	GO:0045979	55	0.030
positive regulation of neurogenesis	GO:0050769	165	0.030
negative regulation of neuron differentiation	GO:0045665	62	0.030
locomotion	GO:0040011	237	0.030
negative regulation of signaling	GO:0023057	157	0.030
small molecule biosynthetic process	GO:0044283	124	0.030
head development	GO:0060322	247	0.030
nucleobase containing small molecule metabolic process	GO:0055086	316	0.029
transcription dna templated	GO:0006351	377	0.029
lipid biosynthetic process	GO:0008610	128	0.029
protein complex subunit organization	GO:0071822	302	0.028
single organism reproductive process	GO:0044702	297	0.028
cellular response to oxygen containing compound	GO:1901701	386	0.028
negative regulation of developmental process	GO:0051093	125	0.028
neuron projection development	GO:0031175	273	0.028
central nervous system development	GO:0007417	311	0.027
lipid metabolic process	GO:0006629	283	0.027
membrane organization	GO:0061024	94	0.027
response to peptide	GO:1901652	292	0.027
cellular protein localization	GO:0034613	122	0.027
regulation of multicellular organismal development	GO:2000026	376	0.026
regulation of cell development	GO:0060284	263	0.026
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.026
negative regulation of metabolic process	GO:0009892	331	0.026
positive regulation of biosynthetic process	GO:0009891	319	0.026
negative regulation of programmed cell death	GO:0043069	183	0.026
single organism intracellular transport	GO:1902582	166	0.026
intracellular transport	GO:0046907	185	0.025
sexual reproduction	GO:0019953	148	0.025
carbohydrate derivative metabolic process	GO:1901135	346	0.025
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.025
response to growth factor	GO:0070848	189	0.025
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.025
positive regulation of response to stimulus	GO:0048584	285	0.024
negative regulation of apoptotic process	GO:0043066	181	0.024
response to peptide hormone	GO:0043434	278	0.024
negative regulation of neurogenesis	GO:0050768	78	0.024
ribose phosphate metabolic process	GO:0019693	235	0.024
regulation of apoptotic process	GO:0042981	335	0.023
cell projection organization	GO:0030030	302	0.023
regulation of cell morphogenesis	GO:0022604	77	0.023
alcohol metabolic process	GO:0006066	77	0.023
behavior	GO:0007610	205	0.023
negative regulation of biosynthetic process	GO:0009890	168	0.023
bmp signaling pathway	GO:0030509	4	0.023
purine nucleoside metabolic process	GO:0042278	169	0.022
organophosphate biosynthetic process	GO:0090407	143	0.022
negative regulation of cell development	GO:0010721	82	0.022
organic substance catabolic process	GO:1901575	316	0.022
negative regulation of response to stimulus	GO:0048585	155	0.022
rna biosynthetic process	GO:0032774	380	0.022
synaptic growth at neuromuscular junction	GO:0051124	1	0.022
regulation of cellular ketone metabolic process	GO:0010565	27	0.022
regulation of growth	GO:0040008	105	0.022
programmed cell death	GO:0012501	392	0.022
regulation of protein metabolic process	GO:0051246	289	0.021
cellular component morphogenesis	GO:0032989	155	0.021
cgmp biosynthetic process	GO:0006182	15	0.021
regulation of rna metabolic process	GO:0051252	391	0.021
regulation of cell differentiation	GO:0045595	320	0.021
brain development	GO:0007420	247	0.021
nucleobase containing compound catabolic process	GO:0034655	152	0.021
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.021
positive regulation of catalytic activity	GO:0043085	184	0.021
purine containing compound catabolic process	GO:0072523	138	0.021
purine nucleotide catabolic process	GO:0006195	136	0.021
regulation of nucleotide metabolic process	GO:0006140	117	0.021
regulation of nucleic acid templated transcription	GO:1903506	380	0.021
cellular nitrogen compound catabolic process	GO:0044270	163	0.021
immune system process	GO:0002376	204	0.021
regulation of neuron differentiation	GO:0045664	208	0.021
cellular response to hormone stimulus	GO:0032870	247	0.021
regulation of nervous system development	GO:0051960	264	0.021
nucleoside phosphate metabolic process	GO:0006753	283	0.021
cell morphogenesis	GO:0000902	142	0.021
positive regulation of cell differentiation	GO:0045597	217	0.021
anatomical structure morphogenesis	GO:0009653	298	0.020
protein phosphorylation	GO:0006468	345	0.020
localization of cell	GO:0051674	202	0.020
synaptic transmission	GO:0007268	235	0.020
organic hydroxy compound transport	GO:0015850	77	0.019
positive regulation of secretion	GO:0051047	140	0.019
negative regulation of cellular component organization	GO:0051129	83	0.019
positive regulation of cellular amine metabolic process	GO:0033240	3	0.019
negative regulation of macromolecule metabolic process	GO:0010605	260	0.019
phosphatidylcholine biosynthetic process	GO:0006656	5	0.019
response to inorganic substance	GO:0010035	377	0.019
reproduction	GO:0000003	245	0.019
organic cyclic compound catabolic process	GO:1901361	175	0.019
gamete generation	GO:0007276	124	0.019
microtubule based process	GO:0007017	36	0.019
transcription from rna polymerase ii promoter	GO:0006366	252	0.019
positive regulation of multicellular organismal process	GO:0051240	387	0.019
regulation of neuron projection development	GO:0010975	161	0.018
axon development	GO:0061564	96	0.018
cellular lipid metabolic process	GO:0044255	208	0.018
nucleoside triphosphate metabolic process	GO:0009141	144	0.018
nucleoside phosphate catabolic process	GO:1901292	140	0.018
nucleoside triphosphate catabolic process	GO:0009143	123	0.018
regulation of rna biosynthetic process	GO:2001141	381	0.018
regulation of purine nucleotide metabolic process	GO:1900542	115	0.018
ribonucleoside metabolic process	GO:0009119	174	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.018
regulation of cell projection organization	GO:0031344	175	0.017
organophosphate catabolic process	GO:0046434	148	0.017
positive regulation of nervous system development	GO:0051962	178	0.017
cellular macromolecule localization	GO:0070727	122	0.017
negative regulation of cell communication	GO:0010648	158	0.017
spindle organization	GO:0007051	2	0.017
cellular amino acid metabolic process	GO:0006520	107	0.017
regulation of transcription dna templated	GO:0006355	374	0.017
response to glucocorticoid	GO:0051384	223	0.017
axon cargo transport	GO:0008088	1	0.017
rna metabolic process	GO:0016070	406	0.017
regulation of developmental growth	GO:0048638	45	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.017
glycerophospholipid metabolic process	GO:0006650	47	0.017
endomembrane system organization	GO:0010256	48	0.017
alcohol biosynthetic process	GO:0046165	38	0.016
positive regulation of molecular function	GO:0044093	230	0.016
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.016
axis specification	GO:0009798	4	0.016
multicellular organism reproduction	GO:0032504	233	0.016
response to nutrient levels	GO:0031667	370	0.016
positive regulation of transport	GO:0051050	245	0.016
protein modification by small protein conjugation or removal	GO:0070647	35	0.016
negative regulation of cell death	GO:0060548	229	0.016
single organism catabolic process	GO:0044712	283	0.016
cyclic purine nucleotide metabolic process	GO:0052652	62	0.016
cell part morphogenesis	GO:0032990	123	0.016
establishment of protein localization to organelle	GO:0072594	44	0.016
ras protein signal transduction	GO:0007265	29	0.016
apoptotic process	GO:0006915	381	0.016
positive regulation of cell communication	GO:0010647	271	0.016
positive regulation of cellular biosynthetic process	GO:0031328	295	0.016
asymmetric protein localization	GO:0008105	2	0.016
regulation of cell motility	GO:2000145	131	0.016
heterocycle catabolic process	GO:0046700	167	0.015
positive regulation of phosphorus metabolic process	GO:0010562	262	0.015
positive regulation of cellular component organization	GO:0051130	200	0.015
cellular response to endogenous stimulus	GO:0071495	377	0.015
cytoplasmic transport	GO:0016482	115	0.015
positive regulation of cell projection organization	GO:0031346	111	0.015
regulation of axonogenesis	GO:0050770	37	0.015
proteolysis	GO:0006508	175	0.015
cell migration	GO:0016477	197	0.015
cell motility	GO:0048870	202	0.015
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.015
regulation of kinase activity	GO:0043549	117	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.014
regulation of bmp signaling pathway	GO:0030510	2	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.014
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.014
cell projection morphogenesis	GO:0048858	123	0.014
regulation of establishment of protein localization	GO:0070201	69	0.014
transmembrane transport	GO:0055085	412	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.014
negative regulation of cell cycle phase transition	GO:1901988	4	0.014
response to extracellular stimulus	GO:0009991	380	0.014
ion transmembrane transport	GO:0034220	365	0.014
negative regulation of signal transduction	GO:0009968	83	0.014
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.014
cell fate determination	GO:0001709	2	0.014
positive regulation of secretion by cell	GO:1903532	128	0.014
antigen processing and presentation	GO:0019882	2	0.014
atp catabolic process	GO:0006200	54	0.014
exocytosis	GO:0006887	60	0.014
organic hydroxy compound biosynthetic process	GO:1901617	51	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.013
calcium ion transport	GO:0006816	131	0.013
cellular response to stress	GO:0033554	269	0.013
response to radiation	GO:0009314	137	0.013
negative regulation of gene expression	GO:0010629	199	0.013
cell cycle	GO:0007049	101	0.013
aging	GO:0007568	241	0.013
rna localization	GO:0006403	4	0.013
multicellular organism growth	GO:0035264	1	0.013
positive regulation of neuron projection development	GO:0010976	99	0.013
anion transport	GO:0006820	178	0.013
chromosome segregation	GO:0007059	2	0.013
regulation of purine nucleotide catabolic process	GO:0033121	65	0.013
cellular response to nitrogen compound	GO:1901699	210	0.013
protein homooligomerization	GO:0051260	91	0.013
small gtpase mediated signal transduction	GO:0007264	36	0.013
negative regulation of cellular biosynthetic process	GO:0031327	161	0.013
taxis	GO:0042330	67	0.013
nucleoside metabolic process	GO:0009116	179	0.013
cellular biogenic amine metabolic process	GO:0006576	30	0.013
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.013
positive regulation of developmental process	GO:0051094	283	0.013
centrosome cycle	GO:0007098	1	0.013
protein transport	GO:0015031	132	0.013
coenzyme metabolic process	GO:0006732	86	0.012
male gamete generation	GO:0048232	99	0.012
purine ribonucleotide biosynthetic process	GO:0009152	81	0.012
protein oligomerization	GO:0051259	191	0.012
ribonucleoside catabolic process	GO:0042454	126	0.012
protein deubiquitination	GO:0016579	4	0.012
atp metabolic process	GO:0046034	72	0.012
organic anion transport	GO:0015711	132	0.012
microtubule organizing center organization	GO:0031023	1	0.012
negative regulation of immune system process	GO:0002683	39	0.012
fertilization	GO:0009566	3	0.012
anterior posterior pattern specification	GO:0009952	1	0.012
positive regulation of cellular component movement	GO:0051272	102	0.012
glycerolipid metabolic process	GO:0046486	67	0.012
organelle localization	GO:0051640	55	0.012
response to estradiol	GO:0032355	164	0.012
glycosyl compound metabolic process	GO:1901657	182	0.012
positive regulation of neuron differentiation	GO:0045666	126	0.012
negative regulation of protein metabolic process	GO:0051248	114	0.012
cellular homeostasis	GO:0019725	252	0.012
monoamine transport	GO:0015844	43	0.012
ribonucleotide catabolic process	GO:0009261	136	0.012
central nervous system neuron axonogenesis	GO:0021955	1	0.012
response to ketone	GO:1901654	182	0.012
regulation of cellular amino acid metabolic process	GO:0006521	2	0.012
regulation of gtpase activity	GO:0043087	57	0.012
cell cycle checkpoint	GO:0000075	2	0.012
cerebral cortex development	GO:0021987	18	0.012
protein modification by small protein conjugation	GO:0032446	31	0.011
single fertilization	GO:0007338	3	0.011
protein localization to organelle	GO:0033365	57	0.011
cyclic nucleotide metabolic process	GO:0009187	80	0.011
regulation of serotonin secretion	GO:0014062	5	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.011
developmental process involved in reproduction	GO:0003006	159	0.011
sensory perception	GO:0007600	101	0.011
spermatogenesis	GO:0007283	99	0.011
regulation of cell proliferation	GO:0042127	359	0.011
positive regulation of nucleotide metabolic process	GO:0045981	91	0.011
regulation of mapk cascade	GO:0043408	116	0.011
positive regulation of signaling	GO:0023056	270	0.011
response to oxidative stress	GO:0006979	186	0.011
nucleoside catabolic process	GO:0009164	126	0.011
regulation of exocytosis	GO:0017157	37	0.011
negative regulation of rna metabolic process	GO:0051253	123	0.011
regulation of cellular component biogenesis	GO:0044087	86	0.011
negative regulation of cell proliferation	GO:0008285	119	0.011
response to carbohydrate	GO:0009743	183	0.011
regulation of intracellular signal transduction	GO:1902531	218	0.011
sister chromatid segregation	GO:0000819	1	0.011
rho protein signal transduction	GO:0007266	11	0.011
regulation of phosphorylation	GO:0042325	248	0.011
carbohydrate derivative biosynthetic process	GO:1901137	124	0.011
cytokine mediated signaling pathway	GO:0019221	43	0.011
regulation of cell growth	GO:0001558	85	0.010
organic acid metabolic process	GO:0006082	292	0.010
neuromuscular process	GO:0050905	2	0.010
response to cytokine	GO:0034097	215	0.010
embryo development	GO:0009790	49	0.010
regulation of transferase activity	GO:0051338	123	0.010
response to external biotic stimulus	GO:0043207	221	0.010
regulation of canonical wnt signaling pathway	GO:0060828	4	0.010
negative regulation of neuron projection development	GO:0010977	46	0.010
metal ion transport	GO:0030001	289	0.010
cell activation	GO:0001775	97	0.010
response to oxygen levels	GO:0070482	265	0.010
regulation of cellular protein metabolic process	GO:0032268	267	0.010
guanosine containing compound catabolic process	GO:1901069	71	0.010
neuron projection morphogenesis	GO:0048812	122	0.010
chemical homeostasis	GO:0048878	292	0.010

Rabep1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.061
nervous system disease	DOID:863	0.061
brain disease	DOID:936	0.032
central nervous system disease	DOID:331	0.032
cerebral degeneration	DOID:1443	0.014

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