Rattus norvegicus

72 known processes

Cftr

cystic fibrosis transmembrane conductance regulator homolog (human)

(Aliases: RGD1561193)

Cftr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrientGO:00075842480.126
response to extracellular stimulusGO:00099913800.100
positive regulation of multicellular organismal processGO:00512403870.098
cell projection organizationGO:00300303020.081
response to molecule of bacterial originGO:00022371940.074
cellular response to oxygen containing compoundGO:19017013860.073
Mouse
response to bacteriumGO:00096172000.071
Zebrafish
regulation of multicellular organismal developmentGO:20000263760.069
cellular response to nitrogen compoundGO:19016992100.064
Mouse
organ regenerationGO:00311001010.057
response to other organismGO:00517072200.057
Zebrafish
reproductive processGO:00224143720.056
Mouse
positive regulation of developmental processGO:00510942830.056
response to nutrient levelsGO:00316673700.056
locomotionGO:00400112370.054
Zebrafish
rna biosynthetic processGO:00327743800.053
regulation of molecular functionGO:00650093980.051
Human
cellular component movementGO:00069282480.051
Zebrafish
intracellular signal transductionGO:00355563140.051
neuron differentiationGO:00301823680.051
cellular homeostasisGO:00197252520.050
Mouse
multicellular organismal reproductive processGO:00486092330.049
Mouse
regulation of nervous system developmentGO:00519602640.048
response to amino acidGO:0043200750.046
regulation of nucleic acid templated transcriptionGO:19035063800.045
head developmentGO:00603222470.043
regulation of angiogenesisGO:0045765390.042
response to external biotic stimulusGO:00432072210.041
Zebrafish
regenerationGO:00310991630.041
reactive oxygen species metabolic processGO:0072593370.039
homeostatic processGO:00425923310.039
Mouse
neurological system processGO:00508772190.039
cell motilityGO:00488702020.038
Zebrafish
positive regulation of cell differentiationGO:00455972170.038
cell migrationGO:00164771970.037
Zebrafish
regulation of anatomical structure morphogenesisGO:00226031410.037
response to lipopolysaccharideGO:00324961910.037
single organism reproductive processGO:00447022970.037
Mouse
chemical homeostasisGO:00488782920.036
Mouse
anatomical structure morphogenesisGO:00096532980.036
response to ketoneGO:19016541820.036
regulation of system processGO:00440572080.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
circulatory system processGO:00030131830.035
positive regulation of cell communicationGO:00106472710.034
regulation of cell motilityGO:20001451310.034
Zebrafish
tissue developmentGO:00098882520.033
cellular response to alcoholGO:0097306870.033
regulation of cell differentiationGO:00455953200.032
positive regulation of angiogenesisGO:0045766280.032
cellular response to biotic stimulusGO:0071216590.031
prostate gland epithelium morphogenesisGO:006074020.030
regulation of blood circulationGO:19035221100.030
cellular response to endogenous stimulusGO:00714953770.030
positive regulation of molecular functionGO:00440932300.030
Human
cardiovascular system developmentGO:00723581340.030
leukocyte migrationGO:0050900380.029
Zebrafish
aromatic compound catabolic processGO:00194391680.029
neuron projection developmentGO:00311752730.029
neuron developmentGO:00486662860.028
proteolysisGO:00065081750.028
amine metabolic processGO:0009308380.028
response to oxidative stressGO:00069791860.027
rna metabolic processGO:00160704060.027
programmed cell deathGO:00125013920.027
central nervous system developmentGO:00074173110.026
circulatory system developmentGO:00723591340.026
transcription dna templatedGO:00063513770.026
catabolic processGO:00090563510.025
defense responseGO:00069521940.025
Zebrafish
regulation of hormone levelsGO:00108171870.025
urogenital system developmentGO:0001655780.025
regulation of cell proliferationGO:00421273590.025
regulation of rna metabolic processGO:00512523910.024
negative regulation of metabolic processGO:00098923310.024
response to monosaccharideGO:00342841590.024
cellular response to organic cyclic compoundGO:00714072020.024
Mouse
response to oxygen levelsGO:00704822650.024
small gtpase mediated signal transductionGO:0007264360.023
positive regulation of catalytic activityGO:00430851840.023
regulation of oxidoreductase activityGO:0051341110.022
transcription from rna polymerase ii promoterGO:00063662520.022
single organism catabolic processGO:00447122830.022
positive regulation of biosynthetic processGO:00098913190.022
protein oligomerizationGO:00512591910.022
reproductionGO:00000032450.022
Mouse
macromolecular complex assemblyGO:00650032730.022
muscle structure developmentGO:0061061870.022
multicellular organism reproductionGO:00325042330.022
Mouse
cellular response to stressGO:00335542690.021
organic cyclic compound catabolic processGO:19013611750.021
blood circulationGO:00080151830.021
alpha amino acid metabolic processGO:1901605710.021
regulation of immune system processGO:00026821230.021
Zebrafish
sensory organ developmentGO:0007423740.021
negative regulation of cell deathGO:00605482290.020
positive regulation of response to stimulusGO:00485842850.020
response to biotic stimulusGO:00096072260.020
Zebrafish
lipid metabolic processGO:00066292830.020
Mouse
regulation of cell developmentGO:00602842630.020
regulation of programmed cell deathGO:00430673410.020
response to peptideGO:19016522920.020
response to ethanolGO:00454711620.019
response to acid chemicalGO:00011012220.019
cellular component assemblyGO:00226073600.019
reproductive structure developmentGO:00486081280.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
protein complex subunit organizationGO:00718223020.019
regulation of neurogenesisGO:00507672470.019
macromolecular complex subunit organizationGO:00439333390.019
cellular catabolic processGO:00442482950.019
regulation of signal transductionGO:00099663180.019
protein complex biogenesisGO:00702712630.019
response to growth factorGO:00708481890.018
protein complex assemblyGO:00064612630.018
regulation of apoptotic processGO:00429813350.018
blood vessel developmentGO:0001568690.018
cellular chemical homeostasisGO:00550822470.018
Mouse
cellular response to organonitrogen compoundGO:00714171970.018
Mouse
positive regulation of locomotionGO:00400171020.018
positive regulation of transportGO:00510502450.017
Human
embryonic appendage morphogenesisGO:003511340.017
cell cell signalingGO:00072673350.017
reactive oxygen species biosynthetic processGO:190340980.017
cellular response to growth factor stimulusGO:00713631620.017
regulation of cell cycleGO:0051726730.017
gland developmentGO:00487321550.017
wound healingGO:00420601220.017
localization of cellGO:00516742020.017
Zebrafish
embryonic limb morphogenesisGO:003032640.017
regulation of kinase activityGO:00435491170.017
protein localizationGO:00081041910.016
negative regulation of multicellular organismal processGO:00512412030.016
estrogen catabolic processGO:000671110.016
regulation of blood vessel sizeGO:0050880890.016
response to woundingGO:00096112540.016
regulation of neuron differentiationGO:00456642080.016
ras protein signal transductionGO:0007265290.016
renal system developmentGO:0072001670.016
appendage morphogenesisGO:003510740.016
cellular response to peptideGO:19016531330.015
cellular amine metabolic processGO:0044106380.015
single organism carbohydrate metabolic processGO:00447231180.015
positive regulation of cellular biosynthetic processGO:00313282950.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
organic substance catabolic processGO:19015753160.015
vascular process in circulatory systemGO:0003018960.015
regulation of mapk cascadeGO:00434081160.015
prostate gland morphogenesisGO:006051220.015
regulation of intracellular signal transductionGO:19025312180.015
secretion by cellGO:00329402480.015
positive regulation of immune system processGO:0002684900.015
regulation of ion transportGO:00432692450.015
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.015
oxoacid metabolic processGO:00434362900.015
positive regulation of intracellular signal transductionGO:19025331380.014
regulation of rna biosynthetic processGO:20011413810.014
cytokine productionGO:0001816610.014
4 chlorobiphenyl metabolic processGO:001888010.014
embryo developmentGO:0009790490.014
response to carbohydrateGO:00097431830.014
regulation of locomotionGO:00400121480.014
Zebrafish
negative regulation of programmed cell deathGO:00430691830.014
gamete generationGO:00072761240.014
Mouse
regulation of protein modification processGO:00313991940.014
regulation of immunoglobulin secretionGO:005102310.014
positive regulation of signalingGO:00230562700.014
regulation of protein secretionGO:0050708280.014
cellular ketone metabolic processGO:0042180510.014
sexual reproductionGO:00199531480.014
Mouse
nitrogen compound transportGO:00717052290.014
response to vitaminGO:00332731310.014
regulation of catalytic activityGO:00507903040.013
negative regulation of innate immune responseGO:004582440.013
cellular response to molecule of bacterial originGO:0071219560.013
cellular amino acid metabolic processGO:00065201070.013
secretionGO:00469033070.013
regulation of cellular amino acid metabolic processGO:000652120.013
vasculature developmentGO:0001944700.013
response to hexoseGO:00097461440.013
regulation of anatomical structure sizeGO:00900661350.013
multi organism reproductive processGO:00447032620.013
Mouse
regulation of transferase activityGO:00513381230.013
tube developmentGO:0035295890.013
regulation of synaptic transmissionGO:00508041410.012
response to alkaloidGO:00432791320.012
response to purine containing compoundGO:00140741260.012
Mouse
regulation of cell adhesionGO:0030155520.012
biological adhesionGO:00226101100.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
axon developmentGO:0061564960.012
regulation of phosphorylationGO:00423252480.012
positive regulation of gene expressionGO:00106282440.012
regulation of cell migrationGO:00303341280.012
Zebrafish
steroid metabolic processGO:0008202730.012
Mouse
inorganic cation transmembrane transportGO:00986622020.012
regulation of neuron projection developmentGO:00109751610.012
negative regulation of response to tumor cellGO:000283520.012
regulation of reactive oxygen species metabolic processGO:2000377260.012
response to starvationGO:0042594590.012
gliogenesisGO:0042063930.012
regulation of renin secretion into blood streamGO:190013310.012
apoptotic processGO:00069153810.012
positive regulation of cell deathGO:00109421840.012
epithelium developmentGO:0060429960.012
regulation of cell projection organizationGO:00313441750.012
response to campGO:0051591910.011
Mouse
sex differentiationGO:00075481130.011
telencephalon developmentGO:0021537620.011
cellular response to lipidGO:00713962010.011
inflammatory responseGO:00069541500.011
male gamete generationGO:0048232990.011
Mouse
regulation of tube sizeGO:0035150890.011
vesicle mediated transportGO:00161921810.011
positive regulation of secretionGO:00510471400.011
regulation of cellular ketone metabolic processGO:0010565270.011
regulation of secretion by cellGO:19035302080.011
negative regulation of molecular functionGO:00440921330.011
ion homeostasisGO:00508012120.011
Mouse
organonitrogen compound catabolic processGO:19015651790.011
growthGO:00400071650.011
spermatogenesisGO:0007283990.011
Mouse
cellular response to ketoneGO:1901655510.011
response to activityGO:0014823730.011
brain developmentGO:00074202470.011
response to hydrogen peroxideGO:0042542890.011
positive regulation of cell developmentGO:00107201760.011
carboxylic acid metabolic processGO:00197522890.011
behavioral response to ethanolGO:004814910.011
phenylpropanoid catabolic processGO:004627130.011
benzene containing compound metabolic processGO:0042537220.011
cell adhesionGO:00071551100.011
positive regulation of protein metabolic processGO:00512471780.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
cell type specific apoptotic processGO:00972851340.011
cellular metal ion homeostasisGO:00068751720.011
regulation of cell cycle g2 m phase transitionGO:190274940.011
protein phosphorylationGO:00064683450.011
response to estrogenGO:00436272320.011
metal ion homeostasisGO:00550651860.011
positive regulation of cellular protein metabolic processGO:00322701670.011
response to hyperoxiaGO:0055093450.011
cofactor metabolic processGO:0051186950.011
cofactor biosynthetic processGO:0051188280.011
positive regulation of cellular amine metabolic processGO:003324030.010
cellular component biogenesisGO:00440853680.010
regulation of cellular amine metabolic processGO:003323880.010
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.010
positive regulation of phosphate metabolic processGO:00459372620.010
agingGO:00075682410.010
antral ovarian follicle growthGO:000154730.010
positive regulation of nucleic acid templated transcriptionGO:19035081970.010
b cell mediated immunityGO:001972440.010
response to axon injuryGO:0048678590.010
regulation of nitric oxide synthase activityGO:005099980.010
hepaticobiliary system developmentGO:0061008900.010
axis specificationGO:000979840.010
regulation of protein transportGO:0051223680.010
negative regulation of oxidoreductase activityGO:005135440.010

Cftr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.016
central nervous system diseaseDOID:33100.012
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
Human