Rattus norvegicus

55 known processes

Shmt2

serine hydroxymethyltransferase 2 (mitochondrial)

(Aliases: MGC105820)

Shmt2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
folic acid containing compound metabolic processGO:0006760100.088
apoptotic processGO:00069153810.065
alpha amino acid metabolic processGO:1901605710.065
regulation of programmed cell deathGO:00430673410.061
regulation of apoptotic processGO:00429813350.056
rna metabolic processGO:00160704060.053
rna biosynthetic processGO:00327743800.050
carboxylic acid metabolic processGO:00197522890.049
nucleic acid templated transcriptionGO:00976593790.048
cofactor metabolic processGO:0051186950.047
cellular amino acid metabolic processGO:00065201070.040
positive regulation of nitrogen compound metabolic processGO:00511733340.040
coenzyme metabolic processGO:0006732860.040
cellular amino acid biosynthetic processGO:0008652320.039
brain developmentGO:00074202470.039
negative regulation of apoptotic processGO:00430661810.038
programmed cell deathGO:00125013920.036
regulation of cellular component organizationGO:00511283680.036
head developmentGO:00603222470.036
cellular modified amino acid metabolic processGO:0006575610.035
oxoacid metabolic processGO:00434362900.034
organelle organizationGO:00069962660.032
positive regulation of biosynthetic processGO:00098913190.032
regulation of nervous system developmentGO:00519602640.031
response to inorganic substanceGO:00100353770.030
negative regulation of macromolecule metabolic processGO:00106052600.030
negative regulation of metabolic processGO:00098923310.027
negative regulation of programmed cell deathGO:00430691830.027
anatomical structure morphogenesisGO:00096532980.026
amine metabolic processGO:0009308380.026
pteridine containing compound metabolic processGO:0042558140.026
reproductionGO:00000032450.025
regulation of transcription dna templatedGO:00063553740.025
agingGO:00075682410.025
negative regulation of cell deathGO:00605482290.025
cellular amine metabolic processGO:0044106380.024
nucleotide metabolic processGO:00091172790.024
positive regulation of apoptotic processGO:00430651540.024
neuron differentiationGO:00301823680.024
regulation of cell differentiationGO:00455953200.023
transcription dna templatedGO:00063513770.023
tetrahydrofolate metabolic processGO:004665390.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
organophosphate metabolic processGO:00196373700.022
positive regulation of immune system processGO:0002684900.022
regulation of rna biosynthetic processGO:20011413810.022
positive regulation of cell deathGO:00109421840.022
positive regulation of gene expressionGO:00106282440.022
cellular component assemblyGO:00226073600.021
regulation of neuron differentiationGO:00456642080.021
organonitrogen compound biosynthetic processGO:19015661670.021
positive regulation of programmed cell deathGO:00430681570.021
transmembrane transportGO:00550854120.021
negative regulation of cellular metabolic processGO:00313242810.020
regulation of neurogenesisGO:00507672470.020
response to metal ionGO:00100382530.020
response to oxygen levelsGO:00704822650.020
ion transmembrane transportGO:00342203650.020
transcription from rna polymerase ii promoterGO:00063662520.020
cellular modified amino acid biosynthetic processGO:0042398180.020
regulation of rna metabolic processGO:00512523910.020
single organism biosynthetic processGO:00447113420.019
regulation of intracellular signal transductionGO:19025312180.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
nucleoside phosphate metabolic processGO:00067532830.019
nucleobase containing small molecule metabolic processGO:00550863160.019
organic acid metabolic processGO:00060822920.019
blood circulationGO:00080151830.019
reproductive processGO:00224143720.019
homeostatic processGO:00425923310.018
positive regulation of mitochondrion organizationGO:001082240.018
regulation of response to stressGO:00801341260.018
response to ketoneGO:19016541820.018
single organism reproductive processGO:00447022970.018
central nervous system developmentGO:00074173110.017
positive regulation of cellular component organizationGO:00511302000.017
response to hypoxiaGO:00016662310.017
positive regulation of cellular biosynthetic processGO:00313282950.017
response to decreased oxygen levelsGO:00362932370.017
cellular response to cytokine stimulusGO:00713451270.017
cell type specific apoptotic processGO:00972851340.017
regulation of cell developmentGO:00602842630.016
response to oxidative stressGO:00069791860.016
chemical homeostasisGO:00488782920.016
cation transportGO:00068123820.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
regulation of cellular protein metabolic processGO:00322682670.016
single organism organelle organizationGO:19025891800.016
regulation of protein metabolic processGO:00512462890.016
circulatory system processGO:00030131830.015
positive regulation of multicellular organismal processGO:00512403870.015
positive regulation of response to stimulusGO:00485842850.015
cellular response to oxygen containing compoundGO:19017013860.015
response to toxic substanceGO:00096361330.015
nitrogen compound transportGO:00717052290.015
regulation of multicellular organismal developmentGO:20000263760.015
organic substance catabolic processGO:19015753160.015
response to corticosteroidGO:00319602350.014
dna metabolic processGO:0006259960.014
negative regulation of gene expressionGO:00106291990.014
positive regulation of nervous system developmentGO:00519621780.014
cellular homeostasisGO:00197252520.014
response to acid chemicalGO:00011012220.014
positive regulation of rna biosynthetic processGO:19026801970.014
regulation of cellular amino acid metabolic processGO:000652120.014
neuron projection developmentGO:00311752730.014
negative regulation of cellular biosynthetic processGO:00313271610.014
organic acid biosynthetic processGO:0016053830.014
protein complex biogenesisGO:00702712630.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
response to purine containing compoundGO:00140741260.014
neurological system processGO:00508772190.014
multicellular organismal reproductive processGO:00486092330.014
positive regulation of cellular amine metabolic processGO:003324030.014
negative regulation of protein metabolic processGO:00512481140.014
regulation of cellular amine metabolic processGO:003323880.014
regulation of nucleic acid templated transcriptionGO:19035063800.013
small gtpase mediated signal transductionGO:0007264360.013
carbohydrate derivative metabolic processGO:19011353460.013
signal transduction by phosphorylationGO:00230141440.013
single organism catabolic processGO:00447122830.013
cell cycle checkpointGO:000007520.013
organic anion transportGO:00157111320.013
purine containing compound metabolic processGO:00725212530.013
response to alkaloidGO:00432791320.013
macromolecular complex subunit organizationGO:00439333390.013
positive regulation of rna metabolic processGO:00512542030.013
vesicle mediated transportGO:00161921810.013
response to biotic stimulusGO:00096072260.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
single organism carbohydrate metabolic processGO:00447231180.013
anion transportGO:00068201780.013
positive regulation of intracellular signal transductionGO:19025331380.013
organic acid transportGO:00158491160.013
organophosphate biosynthetic processGO:00904071430.012
regulation of catalytic activityGO:00507903040.012
response to molecule of bacterial originGO:00022371940.012
protein complex assemblyGO:00064612630.012
negative regulation of signalingGO:00230571570.012
protein phosphorylationGO:00064683450.012
response to cytokineGO:00340972150.012
neuron deathGO:00709971270.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
sex differentiationGO:00075481130.012
negative regulation of biosynthetic processGO:00098901680.012
cellular response to biotic stimulusGO:0071216590.012
cellular chemical homeostasisGO:00550822470.012
response to bacteriumGO:00096172000.012
mapk cascadeGO:00001651400.012
carboxylic acid biosynthetic processGO:0046394830.012
regulation of signal transductionGO:00099663180.012
response to extracellular stimulusGO:00099913800.012
cofactor biosynthetic processGO:0051188280.012
cellular ketone metabolic processGO:0042180510.012
macromolecule localizationGO:00330362520.012
macromolecular complex assemblyGO:00650032730.012
response to lipopolysaccharideGO:00324961910.012
gliogenesisGO:0042063930.011
intracellular signal transductionGO:00355563140.011
neural crest cell developmentGO:001403220.011
negative regulation of multicellular organismal processGO:00512412030.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
cellular component biogenesisGO:00440853680.011
smooth muscle cell proliferationGO:0048659770.011
asymmetric protein localizationGO:000810520.011
positive regulation of cell developmentGO:00107201760.011
purine nucleoside metabolic processGO:00422781690.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
amino acid transportGO:0006865700.011
cellular cation homeostasisGO:00300031800.011
coenzyme biosynthetic processGO:0009108220.011
regulation of anatomical structure morphogenesisGO:00226031410.011
cellular response to stressGO:00335542690.011
response to light stimulusGO:0009416520.011
positive regulation of molecular functionGO:00440932300.011
chromosome segregationGO:000705920.011
nucleoside metabolic processGO:00091161790.011
lipid storageGO:001991510.011
regulation of cellular ketone metabolic processGO:0010565270.011
positive regulation of protein metabolic processGO:00512471780.011
ribose phosphate metabolic processGO:00196932350.010
immune system processGO:00023762040.010
nucleoside monophosphate biosynthetic processGO:0009124280.010
glial cell differentiationGO:0010001650.010
oxidation reduction processGO:00551143040.010
folic acid containing compound biosynthetic processGO:000939640.010
response to ethanolGO:00454711620.010
negative regulation of cell communicationGO:00106481580.010
positive regulation of phosphorylationGO:00423271770.010
gastrulationGO:000736920.010
response to nutrient levelsGO:00316673700.010
negative regulation of neurogenesisGO:0050768780.010
regulation of phosphorylationGO:00423252480.010
regulation of molecular functionGO:00650093980.010
cellular nitrogen compound catabolic processGO:00442701630.010

Shmt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
disease of metabolismDOID:001466700.016
organ system cancerDOID:005068600.013
gastrointestinal system cancerDOID:311900.013
large intestine cancerDOID:567200.013
intestinal cancerDOID:1015500.013
colorectal cancerDOID:925600.013
colon cancerDOID:21900.013
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
myopathyDOID:42300.012