Rattus norvegicus

46 known processes

Shmt1

serine hydroxymethyltransferase 1 (soluble)

(Aliases: Shmt,mShmt,LRRGT00032)

Shmt1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid biosynthetic processGO:0008652320.288
pteridine containing compound metabolic processGO:0042558140.250
Human
cellular modified amino acid biosynthetic processGO:0042398180.174
response to metal ionGO:00100382530.159
alpha amino acid biosynthetic processGO:1901607230.150
response to inorganic substanceGO:00100353770.131
alpha amino acid metabolic processGO:1901605710.088
carboxylic acid metabolic processGO:00197522890.078
tetrahydrofolate metabolic processGO:004665390.073
cellular modified amino acid metabolic processGO:0006575610.063
Human
cellular amino acid metabolic processGO:00065201070.063
nucleobase containing small molecule metabolic processGO:00550863160.060
Human
response to transition metal nanoparticleGO:19902671220.058
liver developmentGO:0001889900.057
regulation of molecular functionGO:00650093980.056
macromolecular complex subunit organizationGO:00439333390.056
regulation of cell differentiationGO:00455953200.055
eye morphogenesisGO:004859240.052
regulation of interleukin 1 beta secretionGO:005070630.052
response to extracellular stimulusGO:00099913800.052
rna metabolic processGO:00160704060.051
response to decreased oxygen levelsGO:00362932370.051
response to woundingGO:00096112540.050
apoptotic processGO:00069153810.050
coenzyme metabolic processGO:0006732860.050
Human
dna metabolic processGO:0006259960.049
cellular response to stressGO:00335542690.049
head developmentGO:00603222470.049
response to nutrient levelsGO:00316673700.046
inflammatory responseGO:00069541500.045
cofactor metabolic processGO:0051186950.044
Human
oxoacid metabolic processGO:00434362900.044
transcription dna templatedGO:00063513770.043
multicellular organism reproductionGO:00325042330.043
brain developmentGO:00074202470.042
reproductive processGO:00224143720.042
organic substance catabolic processGO:19015753160.042
Human
organic acid metabolic processGO:00060822920.041
neuron differentiationGO:00301823680.040
response to hypoxiaGO:00016662310.039
protein complex biogenesisGO:00702712630.039
macromolecular complex assemblyGO:00650032730.038
response to amino acidGO:0043200750.036
single organism biosynthetic processGO:00447113420.036
regulation of programmed cell deathGO:00430673410.035
cellular component biogenesisGO:00440853680.035
central nervous system developmentGO:00074173110.035
positive regulation of response to stimulusGO:00485842850.034
regulation of protein modification processGO:00313991940.034
regulation of multicellular organismal developmentGO:20000263760.034
carboxylic acid biosynthetic processGO:0046394830.034
multicellular organismal reproductive processGO:00486092330.033
immune system processGO:00023762040.033
positive regulation of programmed cell deathGO:00430681570.032
regulation of nervous system developmentGO:00519602640.032
single organism reproductive processGO:00447022970.032
nucleoside phosphate metabolic processGO:00067532830.032
heterocycle catabolic processGO:00467001670.031
macromolecule localizationGO:00330362520.031
positive regulation of interleukin 1 beta secretionGO:005071830.030
cellular response to organic cyclic compoundGO:00714072020.030
protein complex subunit organizationGO:00718223020.030
response to bacteriumGO:00096172000.030
regulation of cell developmentGO:00602842630.030
cellular ketone metabolic processGO:0042180510.029
cell type specific apoptotic processGO:00972851340.029
positive regulation of protein metabolic processGO:00512471780.029
positive regulation of apoptotic processGO:00430651540.029
regulation of apoptotic processGO:00429813350.029
positive regulation of cell differentiationGO:00455972170.029
organic cyclic compound catabolic processGO:19013611750.029
dicarboxylic acid metabolic processGO:0043648420.028
Human
response to acid chemicalGO:00011012220.028
protein complex assemblyGO:00064612630.028
response to oxygen levelsGO:00704822650.028
cellular component assemblyGO:00226073600.028
regulation of transcription dna templatedGO:00063553740.027
response to toxic substanceGO:00096361330.027
cellular response to cytokine stimulusGO:00713451270.027
regulation of rna metabolic processGO:00512523910.027
single organism catabolic processGO:00447122830.027
Human
defense responseGO:00069521940.026
nucleic acid templated transcriptionGO:00976593790.026
cellular component movementGO:00069282480.026
regulation of cellular protein metabolic processGO:00322682670.026
negative regulation of cellular metabolic processGO:00313242810.026
protein oligomerizationGO:00512591910.025
response to external biotic stimulusGO:00432072210.025
protein localizationGO:00081041910.025
positive regulation of cellular protein metabolic processGO:00322701670.025
regulation of cellular amino acid metabolic processGO:000652120.025
positive regulation of multicellular organismal processGO:00512403870.025
response to vitaminGO:00332731310.025
organelle organizationGO:00069962660.025
reproductionGO:00000032450.024
anterior posterior pattern specificationGO:000995210.024
response to corticosteroidGO:00319602350.024
response to ethanolGO:00454711620.024
response to molecule of bacterial originGO:00022371940.024
amine metabolic processGO:0009308380.024
regulation of neurogenesisGO:00507672470.023
chemical homeostasisGO:00488782920.023
ribonucleoside metabolic processGO:00091191740.023
regulation of cell morphogenesis involved in differentiationGO:0010769720.023
programmed cell deathGO:00125013920.023
regulation of neuron projection developmentGO:00109751610.023
response to glucocorticoidGO:00513842230.023
nucleoside metabolic processGO:00091161790.023
acute inflammatory response to non antigenic stimulusGO:000252520.023
response to estrogenGO:00436272320.023
homeostatic processGO:00425923310.022
response to oxidative stressGO:00069791860.022
cell projection organizationGO:00300303020.022
negative regulation of macromolecule metabolic processGO:00106052600.022
positive regulation of developmental processGO:00510942830.022
positive regulation of biosynthetic processGO:00098913190.022
small molecule catabolic processGO:0044282590.022
Human
cellular chemical homeostasisGO:00550822470.022
regulation of rna biosynthetic processGO:20011413810.022
organic acid biosynthetic processGO:0016053830.022
positive regulation of cell deathGO:00109421840.022
response to alkaloidGO:00432791320.022
folic acid containing compound metabolic processGO:0006760100.022
Human
metal ion transportGO:00300012890.021
intracellular transportGO:00469071850.021
positive regulation of cell developmentGO:00107201760.021
organonitrogen compound biosynthetic processGO:19015661670.021
agingGO:00075682410.021
cellular amine metabolic processGO:0044106380.021
cellular nitrogen compound catabolic processGO:00442701630.021
negative regulation of metabolic processGO:00098923310.021
negative regulation of cell deathGO:00605482290.020
neuron developmentGO:00486662860.020
regulation of protein metabolic processGO:00512462890.020
regulation of cell motilityGO:20001451310.020
nucleobase containing compound catabolic processGO:00346551520.020
axis specificationGO:000979840.020
positive regulation of retinal cell programmed cell deathGO:004667010.020
organonitrogen compound catabolic processGO:19015651790.020
Human
biological adhesionGO:00226101100.020
wound healingGO:00420601220.020
protein heterooligomerizationGO:0051291890.019
response to lipopolysaccharideGO:00324961910.019
transcription from rna polymerase ii promoterGO:00063662520.019
small molecule biosynthetic processGO:00442831240.019
neuron projection developmentGO:00311752730.019
response to cytokineGO:00340972150.019
negative regulation of cell proliferationGO:00082851190.019
response to cobalt ionGO:0032025120.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
aromatic compound catabolic processGO:00194391680.019
cellular modified amino acid catabolic processGO:004221910.019
gliogenesisGO:0042063930.019
regulation of system processGO:00440572080.019
cellular macromolecule localizationGO:00707271220.019
negative regulation of neurogenesisGO:0050768780.018
regulation of circadian sleep wake cycle sleepGO:0045187180.018
response to ketoneGO:19016541820.018
response to estradiolGO:00323551640.018
hepaticobiliary system developmentGO:0061008900.018
regulation of intracellular signal transductionGO:19025312180.018
response to nicotineGO:0035094510.018
cellular response to external stimulusGO:00714961180.018
localization of cellGO:00516742020.018
response to nutrientGO:00075842480.017
positive regulation of phosphate metabolic processGO:00459372620.017
regulation of cell projection organizationGO:00313441750.017
intracellular signal transductionGO:00355563140.017
rna biosynthetic processGO:00327743800.017
ion homeostasisGO:00508012120.017
locomotionGO:00400112370.017
telencephalon developmentGO:0021537620.016
regulation of phosphate metabolic processGO:00192203490.016
transmembrane transportGO:00550854120.016
response to peptide hormoneGO:00434342780.016
negative regulation of biosynthetic processGO:00098901680.016
cellular homeostasisGO:00197252520.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
cation homeostasisGO:00550801950.016
single organism organelle organizationGO:19025891800.016
developmental process involved in reproductionGO:00030061590.016
positive regulation of signalingGO:00230562700.016
purine nucleoside metabolic processGO:00422781690.016
single organism intracellular transportGO:19025821660.016
regulation of cellular amine metabolic processGO:003323880.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
regulation of cellular ketone metabolic processGO:0010565270.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
purine ribonucleoside metabolic processGO:00461281680.015
cellular response to peptideGO:19016531330.015
ribonucleoside monophosphate metabolic processGO:0009161880.015
protein phosphorylationGO:00064683450.015
protein transportGO:00150311320.015
cellular response to lipidGO:00713962010.015
cell cycle checkpointGO:000007520.015
positive regulation of nervous system developmentGO:00519621780.015
cell adhesionGO:00071551100.015
cell cell signalingGO:00072673350.015
regulation of interleukin 1 secretionGO:005070430.015
ribose phosphate metabolic processGO:00196932350.014
cofactor biosynthetic processGO:0051188280.014
positive regulation of cellular amine metabolic processGO:003324030.014
cellular response to metal ionGO:0071248550.014
purine containing compound metabolic processGO:00725212530.014
Human
glycosyl compound metabolic processGO:19016571820.014
tube developmentGO:0035295890.014
regenerationGO:00310991630.014
reproductive system developmentGO:00614581280.014
positive regulation of interleukin 1 secretionGO:005071630.014
appendage morphogenesisGO:003510740.014
nitrogen compound transportGO:00717052290.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
proteolysisGO:00065081750.014
response to biotic stimulusGO:00096072260.014
positive regulation of gene expressionGO:00106282440.014
response to carbohydrateGO:00097431830.014
regulation of retinal cell programmed cell deathGO:004666810.014
response to reactive oxygen speciesGO:00003021200.014
folic acid containing compound biosynthetic processGO:000939640.014
organophosphate metabolic processGO:00196373700.014
positive regulation of catalytic activityGO:00430851840.014
cellular response to growth factor stimulusGO:00713631620.014
purine nucleoside monophosphate metabolic processGO:0009126840.014
circadian sleep wake cycleGO:0042745230.014
positive regulation of nitrogen compound metabolic processGO:00511733340.014
positive regulation of molecular functionGO:00440932300.013
cellular response to reactive oxygen speciesGO:0034614550.013
regulation of cellular component organizationGO:00511283680.013
regulation of neuron differentiationGO:00456642080.013
catabolic processGO:00090563510.013
Human
cell migrationGO:00164771970.013
regulation of cell proliferationGO:00421273590.013
Rat
cellular catabolic processGO:00442482950.013
Human
sulfur compound metabolic processGO:0006790700.013
ion transmembrane transportGO:00342203650.013
gastrulationGO:000736920.013
protein homooligomerizationGO:0051260910.013
regulation of catalytic activityGO:00507903040.013
rhythmic processGO:00485111560.013
negative regulation of protein metabolic processGO:00512481140.013
forebrain developmentGO:0030900980.013
negative regulation of programmed cell deathGO:00430691830.013
cellular response to oxidative stressGO:0034599760.013
lens development in camera type eyeGO:0002088130.013
negative regulation of nervous system developmentGO:0051961790.013
carboxylic acid catabolic processGO:0046395490.013
Human
regulation of protein phosphorylationGO:00019321830.013
gland developmentGO:00487321550.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
positive regulation of neurogenesisGO:00507691650.012
reactive oxygen species metabolic processGO:0072593370.012
positive regulation of cell communicationGO:00106472710.012
cell growthGO:00160491040.012
muscle cell proliferationGO:0033002840.012
sensory organ developmentGO:0007423740.012
regulation of response to stressGO:00801341260.012
limb morphogenesisGO:003510840.012
microtubule organizing center organizationGO:003102310.012
cellular response to steroid hormone stimulusGO:0071383930.012
gamete generationGO:00072761240.012
multi organism reproductive processGO:00447032620.012
growthGO:00400071650.012
anatomical structure morphogenesisGO:00096532980.012
cell cycle processGO:0022402570.012
positive regulation of phosphorus metabolic processGO:00105622620.012
rna localizationGO:000640340.012
coenzyme biosynthetic processGO:0009108220.012
carbohydrate derivative metabolic processGO:19011353460.012
sulfur amino acid metabolic processGO:000009690.012
negative regulation of neuron differentiationGO:0045665620.012
axon developmentGO:0061564960.012
organophosphate biosynthetic processGO:00904071430.012
response to hydrogen peroxideGO:0042542890.012
negative regulation of cell cycle phase transitionGO:190198840.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
negative regulation of cell developmentGO:0010721820.012
positive regulation of cell proliferationGO:00082842490.012
Rat
protein maturationGO:0051604680.012
regulation of hydrolase activityGO:00513361430.011
double strand break repairGO:000630210.011
rhythmic behaviorGO:0007622240.011
organ morphogenesisGO:0009887750.011
circadian rhythmGO:0007623880.011
regulation of anatomical structure morphogenesisGO:00226031410.011
gonad developmentGO:00084061040.011
cellular response to endogenous stimulusGO:00714953770.011
neurological system processGO:00508772190.011
negative regulation of cell differentiationGO:0045596990.011
positive regulation of phosphorylationGO:00423271770.011
cell cycleGO:00070491010.011
negative regulation of cellular protein metabolic processGO:00322691060.011
response to glucoseGO:00097491360.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
single organism cell adhesionGO:0098602460.011
ribonucleoside catabolic processGO:00424541260.011
glial cell differentiationGO:0010001650.011
cellular component morphogenesisGO:00329891550.011
positive regulation of signal transductionGO:00099671750.011
mitotic cell cycleGO:0000278490.011
positive regulation of transportGO:00510502450.011
defense response to gram negative bacteriumGO:005082930.010
organ regenerationGO:00311001010.010
negative regulation of cellular component organizationGO:0051129830.010
regulation of canonical wnt signaling pathwayGO:006082840.010
organophosphate catabolic processGO:00464341480.010
response to ionizing radiationGO:0010212590.010
centrosome organizationGO:005129710.010
sexual reproductionGO:00199531480.010
regulation of cell growthGO:0001558850.010
negative regulation of multicellular organismal processGO:00512412030.010
protein processingGO:0016485680.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
cell motilityGO:00488702020.010
circadian behaviorGO:0048512240.010
response to peptideGO:19016522920.010
positive regulation of transcription dna templatedGO:00458931970.010
regulation of cellular localizationGO:00603412630.010
negative regulation of rna metabolic processGO:00512531230.010
regulation of cellular component movementGO:00512701500.010
response to cadmium ionGO:0046686350.010

Shmt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.018
disease of metabolismDOID:001466700.017
cancerDOID:16200.015
organ system cancerDOID:005068600.012
inherited metabolic disorderDOID:65500.012
nervous system diseaseDOID:86300.011
disease of anatomical entityDOID:700.011