IMP: Integrative Multi-species Prediction

Rattus norvegicus

13 known processes

Rab7a

RAB7A, member RAS oncogene family

(Aliases: Rab7)

RGD: 61908
Ensembl: ENSRNOG00000012247
Entrez: 29448
UniProtKB: P09527

Process Predictions
Disease Predictions

Rab7a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular response to stress	GO:0033554	269	0.413
macromolecular complex assembly	GO:0065003	273	0.339
macromolecule localization	GO:0033036	252	0.267	Yeast Fly
response to inorganic substance	GO:0010035	377	0.258
small gtpase mediated signal transduction	GO:0007264	36	0.217
cellular protein localization	GO:0034613	122	0.203	Yeast
protein complex biogenesis	GO:0070271	263	0.202
regulation of neuron projection development	GO:0010975	161	0.193
intracellular signal transduction	GO:0035556	314	0.187
protein transport	GO:0015031	132	0.184
vesicle mediated transport	GO:0016192	181	0.180	Yeast Fly
regulation of anatomical structure morphogenesis	GO:0022603	141	0.177
neuron projection development	GO:0031175	273	0.177
cell projection morphogenesis	GO:0048858	123	0.162
regulation of cell development	GO:0060284	263	0.155
neuron differentiation	GO:0030182	368	0.153
response to metal ion	GO:0010038	253	0.152
positive regulation of secretion	GO:0051047	140	0.147
establishment of protein localization	GO:0045184	141	0.141
anatomical structure morphogenesis	GO:0009653	298	0.130	Fly
regulation of multicellular organismal development	GO:2000026	376	0.129
cellular macromolecule localization	GO:0070727	122	0.128	Yeast
regulation of cell differentiation	GO:0045595	320	0.128
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.120
cell morphogenesis	GO:0000902	142	0.119
positive regulation of cell communication	GO:0010647	271	0.119
regulation of cell morphogenesis	GO:0022604	77	0.117
protein localization to membrane	GO:0072657	36	0.116
regulation of phosphorus metabolic process	GO:0051174	349	0.115
regulation of neuron differentiation	GO:0045664	208	0.113
single organism intracellular transport	GO:1902582	166	0.112	Yeast Fly
negative regulation of neurogenesis	GO:0050768	78	0.112
cellular chemical homeostasis	GO:0055082	247	0.108
cell projection organization	GO:0030030	302	0.104
regulation of hydrolase activity	GO:0051336	143	0.104
regulation of catalytic activity	GO:0050790	304	0.101
regulation of cell projection organization	GO:0031344	175	0.100
regulation of nervous system development	GO:0051960	264	0.098
negative regulation of cell development	GO:0010721	82	0.096
neuron development	GO:0048666	286	0.094
cardiac ventricle development	GO:0003231	1	0.093
ras protein signal transduction	GO:0007265	29	0.091
positive regulation of multicellular organismal process	GO:0051240	387	0.089
protein targeting to membrane	GO:0006612	11	0.088
aromatic compound catabolic process	GO:0019439	168	0.088	Yeast
regulation of molecular function	GO:0065009	398	0.086
protein prenylation	GO:0018342	4	0.084
positive regulation of molecular function	GO:0044093	230	0.080
positive regulation of signaling	GO:0023056	270	0.080
regulation of cellular component organization	GO:0051128	368	0.080	Yeast
regulation of protein phosphorylation	GO:0001932	183	0.079
positive regulation of response to stimulus	GO:0048584	285	0.078
regulation of peptide transport	GO:0090087	87	0.073
response to alkaloid	GO:0043279	132	0.070
protein dephosphorylation	GO:0006470	38	0.067
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.067
golgi vesicle transport	GO:0048193	22	0.066
cellular component biogenesis	GO:0044085	368	0.066
regulation of stem cell differentiation	GO:2000736	2	0.063
cellular component assembly	GO:0022607	360	0.063
negative regulation of nervous system development	GO:0051961	79	0.063
cellular response to growth factor stimulus	GO:0071363	162	0.062
protein complex assembly	GO:0006461	263	0.059
purine nucleoside catabolic process	GO:0006152	124	0.058	Yeast
regulation of axonogenesis	GO:0050770	37	0.058
protein oligomerization	GO:0051259	191	0.058
macromolecular complex subunit organization	GO:0043933	339	0.057
secretion	GO:0046903	307	0.057
protein localization	GO:0008104	191	0.054	Yeast
negative regulation of transcription dna templated	GO:0045892	116	0.053
smad protein complex assembly	GO:0007183	1	0.053
single organism membrane organization	GO:0044802	74	0.053	Yeast
regulation of rna biosynthetic process	GO:2001141	381	0.052
negative regulation of rna metabolic process	GO:0051253	123	0.052
regulation of protein transport	GO:0051223	68	0.051
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.051
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.050
regulation of protein metabolic process	GO:0051246	289	0.049
membrane organization	GO:0061024	94	0.049	Yeast
positive regulation of biosynthetic process	GO:0009891	319	0.049
neuron projection morphogenesis	GO:0048812	122	0.048
secretion by cell	GO:0032940	248	0.047
cation homeostasis	GO:0055080	195	0.046
negative regulation of phosphorus metabolic process	GO:0010563	80	0.046
circadian regulation of gene expression	GO:0032922	3	0.046
regulation of hormone secretion	GO:0046883	106	0.045
signal release	GO:0023061	145	0.045
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.044
negative regulation of phosphate metabolic process	GO:0045936	80	0.044
response to carbohydrate	GO:0009743	183	0.044
negative regulation of cell differentiation	GO:0045596	99	0.044
intracellular protein transport	GO:0006886	79	0.043
lipid storage	GO:0019915	1	0.043
regulation of system process	GO:0044057	208	0.043
regulation of establishment of protein localization	GO:0070201	69	0.042
negative regulation of molecular function	GO:0044092	133	0.042
regulation of cellular ketone metabolic process	GO:0010565	27	0.042
regulation of immune system process	GO:0002682	123	0.042
cellular ketone metabolic process	GO:0042180	51	0.042
cellular amino acid metabolic process	GO:0006520	107	0.042
cellular metal ion homeostasis	GO:0006875	172	0.042
cardiac chamber development	GO:0003205	1	0.042
guanosine containing compound catabolic process	GO:1901069	71	0.041	Yeast
regulation of growth	GO:0040008	105	0.041	Fly
regulation of intracellular signal transduction	GO:1902531	218	0.041
positive regulation of hydrolase activity	GO:0051345	86	0.040
cellular nitrogen compound catabolic process	GO:0044270	163	0.040	Yeast
nitrogen compound transport	GO:0071705	229	0.040	Fly
regulation of protein phosphatase type 2a activity	GO:0034047	2	0.040
positive regulation of developmental process	GO:0051094	283	0.040
p38mapk cascade	GO:0038066	1	0.039
cellular homeostasis	GO:0019725	252	0.039
rna biosynthetic process	GO:0032774	380	0.038
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.038
chemical homeostasis	GO:0048878	292	0.038
single organism biosynthetic process	GO:0044711	342	0.038
response to molecule of bacterial origin	GO:0002237	194	0.037
positive regulation of catalytic activity	GO:0043085	184	0.037
regulation of rna metabolic process	GO:0051252	391	0.037
transcription from rna polymerase ii promoter	GO:0006366	252	0.037
cellular component morphogenesis	GO:0032989	155	0.037
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.037
carbohydrate homeostasis	GO:0033500	75	0.036
response to calcium ion	GO:0051592	59	0.036
circadian rhythm	GO:0007623	88	0.035
negative regulation of cellular component organization	GO:0051129	83	0.035
carbohydrate derivative metabolic process	GO:1901135	346	0.035	Yeast
organic hydroxy compound metabolic process	GO:1901615	115	0.035
regulation of phosphate metabolic process	GO:0019220	349	0.035
heart morphogenesis	GO:0003007	3	0.035
regulation of protein modification process	GO:0031399	194	0.035
cell type specific apoptotic process	GO:0097285	134	0.034
regulation of synaptic transmission	GO:0050804	141	0.034
cell adhesion	GO:0007155	110	0.034
carboxylic acid metabolic process	GO:0019752	289	0.034
hormone secretion	GO:0046879	115	0.034
negative regulation of neuron projection development	GO:0010977	46	0.033
positive regulation of transcription dna templated	GO:0045893	197	0.033
positive regulation of rna metabolic process	GO:0051254	203	0.033
exocytosis	GO:0006887	60	0.033
positive regulation of protein modification process	GO:0031401	142	0.033
ion homeostasis	GO:0050801	212	0.032
peptidyl amino acid modification	GO:0018193	126	0.032
cellular cation homeostasis	GO:0030003	180	0.031
leukocyte activation	GO:0045321	76	0.030
negative regulation of multicellular organismal process	GO:0051241	203	0.030
protein autophosphorylation	GO:0046777	66	0.030
metal ion homeostasis	GO:0055065	186	0.030
biological adhesion	GO:0022610	110	0.030
endocytosis	GO:0006897	84	0.030	Yeast Fly
nucleoside catabolic process	GO:0009164	126	0.030	Yeast
chromosome segregation	GO:0007059	2	0.030
lung development	GO:0030324	43	0.029
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.029
intracellular transport	GO:0046907	185	0.029	Yeast Fly
head development	GO:0060322	247	0.029
cellular ion homeostasis	GO:0006873	184	0.029
positive regulation of protein polymerization	GO:0032273	10	0.028
muscle system process	GO:0003012	115	0.028
rna metabolic process	GO:0016070	406	0.028
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.028
lipid localization	GO:0010876	62	0.027
hormone transport	GO:0009914	121	0.027
nucleic acid templated transcription	GO:0097659	379	0.027
regulation of protein kinase activity	GO:0045859	105	0.027
cellular response to abiotic stimulus	GO:0071214	85	0.027
immune system process	GO:0002376	204	0.027
arf protein signal transduction	GO:0032011	0	0.027
regulation of cellular amine metabolic process	GO:0033238	8	0.027
positive regulation of cellular component organization	GO:0051130	200	0.027
nucleobase containing small molecule metabolic process	GO:0055086	316	0.027	Yeast
neuron death	GO:0070997	127	0.026
oxoacid metabolic process	GO:0043436	290	0.026
protein geranylgeranylation	GO:0018344	4	0.026
positive regulation of protein metabolic process	GO:0051247	178	0.026
central nervous system development	GO:0007417	311	0.026
regulation of protein localization	GO:0032880	81	0.026
purine containing compound metabolic process	GO:0072521	253	0.025	Yeast
regulation of secretion	GO:0051046	224	0.025
positive regulation of cell development	GO:0010720	176	0.025
circulatory system development	GO:0072359	134	0.025
regulation of peptidase activity	GO:0052547	55	0.025
regulation of signal transduction	GO:0009966	318	0.025	Fly
cytoskeleton organization	GO:0007010	111	0.025
protein heterooligomerization	GO:0051291	89	0.024
cell growth	GO:0016049	104	0.024
regulation of actin nucleation	GO:0051125	2	0.024
regulation of arp2 3 complex mediated actin nucleation	GO:0034315	2	0.024
cellular response to nitrogen compound	GO:1901699	210	0.024
response to cytokine	GO:0034097	215	0.024
t cell proliferation	GO:0042098	19	0.024
regulation of secretion by cell	GO:1903530	208	0.024
cell morphogenesis involved in differentiation	GO:0000904	119	0.024
single organism organelle organization	GO:1902589	180	0.024	Yeast
ion transmembrane transport	GO:0034220	365	0.024
regulation of ion transmembrane transport	GO:0034765	121	0.023
dendrite development	GO:0016358	72	0.023
response to organophosphorus	GO:0046683	102	0.023
regulation of phosphorylation	GO:0042325	248	0.023
positive regulation of synaptic transmission	GO:0050806	62	0.023
regulation of i kappab kinase nf kappab signaling	GO:0043122	13	0.023
protein phosphorylation	GO:0006468	345	0.023
response to glucose	GO:0009749	136	0.023
rab protein signal transduction	GO:0032482	1	0.023
negative regulation of protein phosphorylation	GO:0001933	44	0.023
protein complex subunit organization	GO:0071822	302	0.023
hemopoiesis	GO:0030097	34	0.023
axon development	GO:0061564	96	0.022
regulation of protein complex assembly	GO:0043254	33	0.022
cell activation	GO:0001775	97	0.022
positive regulation of programmed cell death	GO:0043068	157	0.022
cellular response to organonitrogen compound	GO:0071417	197	0.022
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.022
purine nucleotide catabolic process	GO:0006195	136	0.021	Yeast
positive regulation of phosphate metabolic process	GO:0045937	262	0.021
response to wounding	GO:0009611	254	0.021
regulation of cellular amino acid metabolic process	GO:0006521	2	0.021
response to oxidative stress	GO:0006979	186	0.021
cytoplasmic transport	GO:0016482	115	0.021	Fly
transcription dna templated	GO:0006351	377	0.021
single organism reproductive process	GO:0044702	297	0.021
regulation of transcription dna templated	GO:0006355	374	0.021
nucleobase containing compound catabolic process	GO:0034655	152	0.021	Yeast
positive regulation of apoptotic process	GO:0043065	154	0.021
positive regulation of cellular protein metabolic process	GO:0032270	167	0.021
negative regulation of neuron differentiation	GO:0045665	62	0.021
glucose homeostasis	GO:0042593	75	0.021
brain development	GO:0007420	247	0.020
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.020	Yeast
tissue development	GO:0009888	252	0.020	Fly
homeostatic process	GO:0042592	331	0.020
dephosphorylation	GO:0016311	98	0.020
negative regulation of metabolic process	GO:0009892	331	0.020
regulation of nucleic acid templated transcription	GO:1903506	380	0.020
cellular response to ethanol	GO:0071361	13	0.020
somatic stem cell division	GO:0048103	2	0.020
regulation of rab gtpase activity	GO:0032313	3	0.020
regulation of synaptic plasticity	GO:0048167	70	0.020
reproduction	GO:0000003	245	0.020
divalent inorganic cation transport	GO:0072511	134	0.020
cellular response to oxygen containing compound	GO:1901701	386	0.020
nucleoside metabolic process	GO:0009116	179	0.020	Yeast
rhythmic process	GO:0048511	156	0.020
regulation of cellular component biogenesis	GO:0044087	86	0.020
regulation of apoptotic process	GO:0042981	335	0.020
negative regulation of macromolecule metabolic process	GO:0010605	260	0.020
response to light stimulus	GO:0009416	52	0.020
gtp metabolic process	GO:0046039	72	0.020	Yeast
negative regulation of erk1 and erk2 cascade	GO:0070373	9	0.020
single organism cellular localization	GO:1902580	102	0.020
nucleoside phosphate catabolic process	GO:1901292	140	0.019	Yeast
response to hexose	GO:0009746	144	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.019	Yeast
negative regulation of cellular metabolic process	GO:0031324	281	0.019
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.019
organelle organization	GO:0006996	266	0.019	Yeast
regulation of hormone levels	GO:0010817	187	0.019
glycerol 3 phosphate metabolic process	GO:0006072	2	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.019
purine nucleoside metabolic process	GO:0042278	169	0.019	Yeast
response to radiation	GO:0009314	137	0.019
muscle organ development	GO:0007517	50	0.019
cell cell signaling	GO:0007267	335	0.019
regulation of neurogenesis	GO:0050767	247	0.018
response to axon injury	GO:0048678	59	0.018
negative regulation of developmental process	GO:0051093	125	0.018
mitotic spindle organization	GO:0007052	2	0.018
erbb signaling pathway	GO:0038127	23	0.018
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.018
heterocycle catabolic process	GO:0046700	167	0.018	Yeast
organic anion transport	GO:0015711	132	0.018
inner ear development	GO:0048839	21	0.018
regulation of nucleotide metabolic process	GO:0006140	117	0.018
response to growth factor	GO:0070848	189	0.018
glycoprotein metabolic process	GO:0009100	24	0.018
amine metabolic process	GO:0009308	38	0.018
positive regulation of protein binding	GO:0032092	9	0.018
tube development	GO:0035295	89	0.017
cellular calcium ion homeostasis	GO:0006874	160	0.017
negative regulation of protein metabolic process	GO:0051248	114	0.017
adult locomotory behavior	GO:0008344	4	0.017
regulation of canonical wnt signaling pathway	GO:0060828	4	0.017
hematopoietic progenitor cell differentiation	GO:0002244	2	0.017
regulation of anatomical structure size	GO:0090066	135	0.017
developmental process involved in reproduction	GO:0003006	159	0.017
positive regulation of cell death	GO:0010942	184	0.017
melanosome localization	GO:0032400	1	0.017
cellular response to cytokine stimulus	GO:0071345	127	0.017
actin nucleation	GO:0045010	2	0.017
cell part morphogenesis	GO:0032990	123	0.017
auditory receptor cell differentiation	GO:0042491	2	0.016
negative regulation of apoptotic process	GO:0043066	181	0.016
regulation of cysteine type endopeptidase activity	GO:2000116	32	0.016
regulation of transmembrane transport	GO:0034762	122	0.016
positive regulation of cellular biosynthetic process	GO:0031328	295	0.016
positive regulation of peptide secretion	GO:0002793	52	0.016
multi organism reproductive process	GO:0044703	262	0.016
negative regulation of protein transport	GO:0051224	17	0.016
fibroblast growth factor receptor signaling pathway	GO:0008543	8	0.016
regulation of peptide secretion	GO:0002791	82	0.016
multicellular organism growth	GO:0035264	1	0.016
positive regulation of rna biosynthetic process	GO:1902680	197	0.016
positive regulation of actin filament polymerization	GO:0030838	5	0.016
purine containing compound catabolic process	GO:0072523	138	0.016	Yeast
purine ribonucleotide metabolic process	GO:0009150	227	0.016	Yeast
regulation of programmed cell death	GO:0043067	341	0.016
negative regulation of gene expression	GO:0010629	199	0.016
nucleoside phosphate metabolic process	GO:0006753	283	0.016	Yeast
regulation of lipid storage	GO:0010883	1	0.015
positive regulation of intracellular signal transduction	GO:1902533	138	0.015
organelle assembly	GO:0070925	22	0.015
histamine secretion involved in inflammatory response	GO:0002441	3	0.015
negative regulation of phosphorylation	GO:0042326	57	0.015
cellular response to hexose stimulus	GO:0071331	65	0.015
cardiac muscle tissue morphogenesis	GO:0055008	1	0.015
regulation of response to stress	GO:0080134	126	0.015
negative regulation of catalytic activity	GO:0043086	103	0.015
regulation of cellular protein metabolic process	GO:0032268	267	0.015
response to mercury ion	GO:0046689	15	0.015
regulation of response to external stimulus	GO:0032101	106	0.015
neuron apoptotic process	GO:0051402	88	0.015
amide transport	GO:0042886	105	0.015
cellular amine metabolic process	GO:0044106	38	0.015
negative regulation of cell death	GO:0060548	229	0.014
peptide transport	GO:0015833	97	0.014
regulation of calcium ion transmembrane transport	GO:1903169	18	0.014
positive regulation of protein transport	GO:0051222	41	0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	10	0.014
positive regulation of organelle organization	GO:0010638	48	0.014
negative regulation of biosynthetic process	GO:0009890	168	0.014
response to nutrient levels	GO:0031667	370	0.014
response to monosaccharide	GO:0034284	159	0.014
regulation of peptide hormone secretion	GO:0090276	80	0.014
carbohydrate derivative catabolic process	GO:1901136	147	0.014	Yeast
positive regulation of glycoprotein metabolic process	GO:1903020	3	0.014
peptide hormone secretion	GO:0030072	84	0.014
regulation of dendrite development	GO:0050773	59	0.014
inorganic cation transmembrane transport	GO:0098662	202	0.014
endomembrane system organization	GO:0010256	48	0.014
calcium ion transmembrane transport	GO:0070588	70	0.014
regulation of proteasomal protein catabolic process	GO:0061136	4	0.014
positive regulation of transport	GO:0051050	245	0.013
calcium ion transport	GO:0006816	131	0.013
muscle structure development	GO:0061061	87	0.013
organic acid metabolic process	GO:0006082	292	0.013
positive regulation of rab gtpase activity	GO:0032851	3	0.013
spindle organization	GO:0007051	2	0.013
cell cycle	GO:0007049	101	0.013
growth	GO:0040007	165	0.013	Fly
regulation of insulin secretion	GO:0050796	65	0.013
response to cadmium ion	GO:0046686	35	0.013
regulation of tube size	GO:0035150	89	0.013
striated muscle tissue development	GO:0014706	58	0.013
positive regulation of signal transduction	GO:0009967	175	0.013
negative regulation of cell projection organization	GO:0031345	50	0.013
guanosine containing compound metabolic process	GO:1901068	74	0.013	Yeast
transmembrane transport	GO:0055085	412	0.013
regulation of developmental growth	GO:0048638	45	0.013
single organism carbohydrate metabolic process	GO:0044723	118	0.013
nucleotide catabolic process	GO:0009166	139	0.013	Yeast
regulation of neuron death	GO:1901214	115	0.013
positive regulation of phosphoprotein phosphatase activity	GO:0032516	3	0.013
response to amino acid	GO:0043200	75	0.013
erythrocyte differentiation	GO:0030218	1	0.013
cellular protein complex assembly	GO:0043623	44	0.013
protein polymerization	GO:0051258	22	0.013
axon cargo transport	GO:0008088	1	0.013
sequestering of metal ion	GO:0051238	9	0.012
cellular response to inorganic substance	GO:0071241	65	0.012
response to peptide hormone	GO:0043434	278	0.012
negative regulation of rna biosynthetic process	GO:1902679	118	0.012
semicircular canal development	GO:0060872	1	0.012
regulation of ras protein signal transduction	GO:0046578	45	0.012
cellular response to carbohydrate stimulus	GO:0071322	72	0.012
macroautophagy	GO:0016236	4	0.012
inorganic ion transmembrane transport	GO:0098660	229	0.012
regulation of homotypic cell cell adhesion	GO:0034110	4	0.012
positive regulation of protein dephosphorylation	GO:0035307	4	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.012
axonogenesis	GO:0007409	71	0.012
spermatogenesis	GO:0007283	99	0.012
organic cyclic compound catabolic process	GO:1901361	175	0.012	Yeast
regulation of organelle organization	GO:0033043	80	0.012	Yeast
tube formation	GO:0035148	3	0.012
regulation of ras gtpase activity	GO:0032318	32	0.012
organic substance catabolic process	GO:1901575	316	0.012	Yeast
actin filament based process	GO:0030029	86	0.012
er to golgi vesicle mediated transport	GO:0006888	10	0.012
microtubule based process	GO:0007017	36	0.012
sex differentiation	GO:0007548	113	0.012
nucleotide metabolic process	GO:0009117	279	0.012	Yeast
response to peptide	GO:1901652	292	0.012
negative regulation of cell communication	GO:0010648	158	0.012
positive regulation of response to external stimulus	GO:0032103	51	0.012
response to mechanical stimulus	GO:0009612	134	0.012
regulation of actin filament based process	GO:0032970	42	0.012
apoptotic process	GO:0006915	381	0.012
actin cytoskeleton organization	GO:0030036	73	0.012
positive regulation of smoothened signaling pathway	GO:0045880	1	0.012
cellular response to external stimulus	GO:0071496	118	0.012
immune system development	GO:0002520	41	0.012
protein localization to organelle	GO:0033365	57	0.012	Yeast
vascular process in circulatory system	GO:0003018	96	0.012
regulation of purine nucleotide metabolic process	GO:1900542	115	0.012
hindbrain morphogenesis	GO:0021575	2	0.012
regulation of kinase activity	GO:0043549	117	0.012
regulation of cell growth	GO:0001558	85	0.012
alcohol metabolic process	GO:0006066	77	0.011
synaptic transmission	GO:0007268	235	0.011
regulation of muscle system process	GO:0090257	79	0.011
organophosphate catabolic process	GO:0046434	148	0.011	Yeast
regulation of notch signaling pathway	GO:0008593	3	0.011	Fly
retina development in camera type eye	GO:0060041	27	0.011
response to purine containing compound	GO:0014074	126	0.011
epidermal growth factor receptor signaling pathway	GO:0007173	23	0.011
regulation of catabolic process	GO:0009894	113	0.011
cellular response to hormone stimulus	GO:0032870	247	0.011
positive regulation of protein phosphorylation	GO:0001934	135	0.011
response to lipopolysaccharide	GO:0032496	191	0.011
regulation of protein targeting to membrane	GO:0090313	3	0.011
respiratory tube development	GO:0030323	43	0.011
cellular response to lipid	GO:0071396	201	0.011
maintenance of location	GO:0051235	17	0.011
plasma membrane organization	GO:0007009	17	0.011
mechanoreceptor differentiation	GO:0042490	2	0.011
microtubule cytoskeleton organization	GO:0000226	25	0.011
regulation of calcium ion transmembrane transporter activity	GO:1901019	17	0.011
positive regulation of catabolic process	GO:0009896	78	0.011
cellular catabolic process	GO:0044248	295	0.011	Yeast
response to biotic stimulus	GO:0009607	226	0.011
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
reproductive system development	GO:0061458	128	0.011
carbohydrate metabolic process	GO:0005975	130	0.011
positive regulation of hormone secretion	GO:0046887	65	0.011
response to follicle stimulating hormone	GO:0032354	18	0.011
glial cell differentiation	GO:0010001	65	0.010
regulation of rab protein signal transduction	GO:0032483	3	0.010
multicellular organism reproduction	GO:0032504	233	0.010
negative regulation of protein modification process	GO:0031400	52	0.010
gtp catabolic process	GO:0006184	71	0.010	Yeast
regulation of dna metabolic process	GO:0051052	60	0.010
positive regulation of gene expression	GO:0010628	244	0.010
cellular response to metal ion	GO:0071248	55	0.010
cation transport	GO:0006812	382	0.010
nuclear transport	GO:0051169	49	0.010
development of primary sexual characteristics	GO:0045137	107	0.010
muscle contraction	GO:0006936	88	0.010
behavior	GO:0007610	205	0.010
regulation of protein polymerization	GO:0032271	19	0.010
ribonucleotide metabolic process	GO:0009259	231	0.010	Yeast
response to transition metal nanoparticle	GO:1990267	122	0.010
negative regulation of transport	GO:0051051	136	0.010
cellular response to glucose stimulus	GO:0071333	65	0.010

Rab7a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.032
disease of anatomical entity	DOID:7	0.032
sensory system disease	DOID:0050155	0.024

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