Rattus norvegicus

129 known processes

Atf4

activating transcription factor 4 (tax-responsive enhancer element B67)

Atf4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron deathGO:00709971270.170
cellular response to stressGO:00335542690.165
programmed cell deathGO:00125013920.145
rna biosynthetic processGO:00327743800.129
nucleic acid templated transcriptionGO:00976593790.113
regulation of apoptotic processGO:00429813350.106
apoptotic processGO:00069153810.103
regulation of rna metabolic processGO:00512523910.100
regulation of programmed cell deathGO:00430673410.088
regulation of neuron apoptotic processGO:0043523830.088
cation transportGO:00068123820.086
response to reactive oxygen speciesGO:00003021200.085
regulation of cell differentiationGO:00455953200.076
cell type specific apoptotic processGO:00972851340.074
intracellular signal transductionGO:00355563140.072
regulation of nucleic acid templated transcriptionGO:19035063800.061
regulation of neuron deathGO:19012141150.059
response to extracellular stimulusGO:00099913800.058
negative regulation of macromolecule biosynthetic processGO:00105581480.057
negative regulation of apoptotic processGO:00430661810.055
transcription from rna polymerase ii promoterGO:00063662520.054
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.052
regulation of protein metabolic processGO:00512462890.052
proteolysisGO:00065081750.051
negative regulation of macromolecule metabolic processGO:00106052600.051
response to hydrogen peroxideGO:0042542890.049
regulation of molecular functionGO:00650093980.049
negative regulation of nucleic acid templated transcriptionGO:19035071170.047
regulation of cellular protein metabolic processGO:00322682670.046
cellular response to oxidative stressGO:0034599760.044
negative regulation of rna metabolic processGO:00512531230.042
positive regulation of apoptotic processGO:00430651540.040
organic substance catabolic processGO:19015753160.040
cofactor metabolic processGO:0051186950.040
response to nutrient levelsGO:00316673700.039
positive regulation of cell deathGO:00109421840.038
neuron apoptotic processGO:0051402880.038
cellular catabolic processGO:00442482950.037
negative regulation of metabolic processGO:00098923310.037
regulation of fat cell differentiationGO:004559830.036
carbohydrate derivative metabolic processGO:19011353460.036
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.036
single organism catabolic processGO:00447122830.036
negative regulation of cell deathGO:00605482290.035
response to decreased oxygen levelsGO:00362932370.034
amino acid transportGO:0006865700.033
cellular response to reactive oxygen speciesGO:0034614550.033
nucleotide metabolic processGO:00091172790.032
small gtpase mediated signal transductionGO:0007264360.032
negative regulation of sequence specific dna binding transcription factor activityGO:0043433110.032
response to nutrientGO:00075842480.032
nucleobase containing small molecule metabolic processGO:00550863160.031
positive regulation of neuron apoptotic processGO:0043525330.031
regulation of rna biosynthetic processGO:20011413810.031
regulation of transcription dna templatedGO:00063553740.030
catabolic processGO:00090563510.029
regulation of catalytic activityGO:00507903040.029
regulation of cell developmentGO:00602842630.029
cellular response to hormone stimulusGO:00328702470.028
positive regulation of nitrogen compound metabolic processGO:00511733340.028
negative regulation of programmed cell deathGO:00430691830.027
mrna transcription from rna polymerase ii promoterGO:004278910.027
negative regulation of rna biosynthetic processGO:19026791180.027
regulation of phosphate metabolic processGO:00192203490.027
organic acid metabolic processGO:00060822920.026
positive regulation of catalytic activityGO:00430851840.026
negative regulation of cellular biosynthetic processGO:00313271610.026
regulation of hydrolase activityGO:00513361430.026
positive regulation of catabolic processGO:0009896780.026
positive regulation of response to stimulusGO:00485842850.026
negative regulation of molecular functionGO:00440921330.025
ribonucleoside catabolic processGO:00424541260.025
negative regulation of cellular protein metabolic processGO:00322691060.025
cellular response to oxygen containing compoundGO:19017013860.025
transcription dna templatedGO:00063513770.025
cation transmembrane transportGO:00986552630.024
rna metabolic processGO:00160704060.024
organonitrogen compound catabolic processGO:19015651790.023
negative regulation of gene expressionGO:00106291990.023
negative regulation of cell differentiationGO:0045596990.023
response to external biotic stimulusGO:00432072210.023
positive regulation of multicellular organismal processGO:00512403870.023
regulation of nucleotide metabolic processGO:00061401170.023
regulation of gene expression epigeneticGO:0040029100.022
positive regulation of molecular functionGO:00440932300.022
negative regulation of transcription dna templatedGO:00458921160.022
regulation of purine nucleotide metabolic processGO:19005421150.022
organic cyclic compound catabolic processGO:19013611750.022
cellular response to endogenous stimulusGO:00714953770.021
protein heterooligomerizationGO:0051291890.021
carboxylic acid metabolic processGO:00197522890.021
positive regulation of protein metabolic processGO:00512471780.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
cellular amino acid biosynthetic processGO:0008652320.020
cellular homeostasisGO:00197252520.020
neuron differentiationGO:00301823680.020
positive regulation of biosynthetic processGO:00098913190.020
heterocycle catabolic processGO:00467001670.020
cellular macromolecule catabolic processGO:0044265290.019
cellular response to biotic stimulusGO:0071216590.019
response to metal ionGO:00100382530.019
ribonucleotide metabolic processGO:00092592310.019
nitrogen compound transportGO:00717052290.019
regulation of transferase activityGO:00513381230.019
ribose phosphate metabolic processGO:00196932350.019
negative regulation of biosynthetic processGO:00098901680.019
multicellular organism reproductionGO:00325042330.019
cellular protein catabolic processGO:0044257190.019
organophosphate metabolic processGO:00196373700.019
response to lipopolysaccharideGO:00324961910.018
axis specificationGO:000979840.018
response to other organismGO:00517072200.018
positive regulation of nucleotide metabolic processGO:0045981910.018
regulation of multicellular organismal developmentGO:20000263760.018
divalent inorganic cation homeostasisGO:00725071650.018
positive regulation of programmed cell deathGO:00430681570.018
single organism carbohydrate metabolic processGO:00447231180.018
cellular ketone metabolic processGO:0042180510.018
maintenance of locationGO:0051235170.018
response to molecule of bacterial originGO:00022371940.018
anterior posterior pattern specificationGO:000995210.018
response to biotic stimulusGO:00096072260.017
ion transmembrane transportGO:00342203650.017
cellular protein localizationGO:00346131220.017
calcium ion transportGO:00068161310.017
reproductive processGO:00224143720.017
growthGO:00400071650.016
purine containing compound metabolic processGO:00725212530.016
cellular response to unfolded proteinGO:003462020.016
organic anion transportGO:00157111320.016
negative regulation of neuron apoptotic processGO:0043524450.016
glycosyl compound metabolic processGO:19016571820.016
negative regulation of response to stimulusGO:00485851550.016
cytoplasmic transportGO:00164821150.015
carboxylic acid transportGO:00469421150.015
small molecule biosynthetic processGO:00442831240.015
positive regulation of nucleoside metabolic processGO:0045979550.015
branched chain amino acid transportGO:001580320.015
intracellular transportGO:00469071850.015
negative regulation of protein metabolic processGO:00512481140.015
positive regulation of developmental processGO:00510942830.015
response to acid chemicalGO:00011012220.015
cellular response to topologically incorrect proteinGO:003596730.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
positive regulation of phosphorus metabolic processGO:00105622620.015
positive regulation of cellular protein metabolic processGO:00322701670.015
tissue developmentGO:00098882520.014
nucleoside phosphate metabolic processGO:00067532830.014
regulation of intracellular signal transductionGO:19025312180.014
cellular amino acid metabolic processGO:00065201070.014
positive regulation of purine nucleotide catabolic processGO:0033123530.014
multi organism reproductive processGO:00447032620.014
d amino acid transportGO:004294010.014
negative regulation of cellular metabolic processGO:00313242810.014
inactivation of mapk activityGO:000018820.014
nucleoside metabolic processGO:00091161790.014
response to hypoxiaGO:00016662310.014
purine containing compound biosynthetic processGO:0072522850.014
regulation of cell proliferationGO:00421273590.014
trna metabolic processGO:000639940.014
purine nucleotide metabolic processGO:00061632290.013
response to oxygen levelsGO:00704822650.013
single organism intracellular transportGO:19025821660.013
defense responseGO:00069521940.013
regulation of nucleotide catabolic processGO:0030811650.013
ras protein signal transductionGO:0007265290.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
organonitrogen compound biosynthetic processGO:19015661670.013
positive regulation of neuron deathGO:1901216430.013
regenerationGO:00310991630.013
nucleobase containing compound catabolic processGO:00346551520.013
divalent metal ion transportGO:00708381320.013
neuron projection developmentGO:00311752730.013
calcium ion homeostasisGO:00550741620.013
cellular response to hydrogen peroxideGO:0070301420.012
transmembrane transportGO:00550854120.012
cellular amine metabolic processGO:0044106380.012
positive regulation of cellular biosynthetic processGO:00313282950.012
negative regulation of transportGO:00510511360.012
regulation of purine nucleotide catabolic processGO:0033121650.012
regulation of phosphorus metabolic processGO:00511743490.012
negative regulation of multicellular organismal processGO:00512412030.012
regulation of signal transductionGO:00099663180.012
regulation of canonical wnt signaling pathwayGO:006082840.012
purine nucleoside metabolic processGO:00422781690.012
cardiovascular system developmentGO:00723581340.012
reproductionGO:00000032450.012
cellular chemical homeostasisGO:00550822470.012
gastrulationGO:000736920.012
hepaticobiliary system developmentGO:0061008900.012
regulation of homeostatic processGO:00328441010.012
response to inorganic substanceGO:00100353770.012
positive regulation of signalingGO:00230562700.012
regulation of phosphorylationGO:00423252480.012
positive regulation of humoral immune responseGO:000292220.012
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154170.012
regulation of kinase activityGO:00435491170.012
agingGO:00075682410.012
amine metabolic processGO:0009308380.012
negative regulation of developmental processGO:00510931250.012
nucleoside triphosphate metabolic processGO:00091411440.011
inorganic cation transmembrane transportGO:00986622020.011
regulation of response to stressGO:00801341260.011
homeostatic processGO:00425923310.011
response to bacteriumGO:00096172000.011
neuron developmentGO:00486662860.011
response to estrogenGO:00436272320.011
peptide biosynthetic processGO:004304330.011
single organism reproductive processGO:00447022970.011
negative regulation of neuron deathGO:1901215690.011
positive regulation of rna biosynthetic processGO:19026801970.011
stress activated protein kinase signaling cascadeGO:0031098370.011
carbohydrate derivative catabolic processGO:19011361470.011
anion transportGO:00068201780.011
amide biosynthetic processGO:0043604100.011
positive regulation of phosphate metabolic processGO:00459372620.011
immune effector processGO:0002252530.011
cellular metal ion homeostasisGO:00068751720.011
nucleoside phosphate catabolic processGO:19012921400.011
regulation of catabolic processGO:00098941130.011
cellular macromolecule localizationGO:00707271220.011
protein targetingGO:0006605610.011
sequestering of metal ionGO:005123890.011
positive regulation of nucleobase containing compound metabolic processGO:00459353190.011
protein localizationGO:00081041910.010
neuron projection regenerationGO:0031102350.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
endochondral bone growthGO:000341630.010
positive regulation of cell proliferationGO:00082842490.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
response to heatGO:0009408600.010
macromolecular complex subunit organizationGO:00439333390.010
multicellular organism growthGO:003526410.010
regulation of anatomical structure sizeGO:00900661350.010
organic acid transportGO:00158491160.010
ion homeostasisGO:00508012120.010
divalent inorganic cation transportGO:00725111340.010
regulation of cellular localizationGO:00603412630.010

Atf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
musculoskeletal system diseaseDOID:1700.012
neuropathyDOID:87000.011
neuromuscular diseaseDOID:44000.011
charcot marie tooth disease type 2DOID:005053900.011
charcot marie tooth diseaseDOID:1059500.011