Rattus norvegicus

50 known processes

Mapt

microtubule-associated protein tau

(Aliases: MGC156663,RNPTAU,pTau,Mtapt)

Mapt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell part morphogenesisGO:00329901230.266
Human
neuron projection developmentGO:00311752730.258
Human
positive regulation of developmental processGO:00510942830.249
Human
cell projection morphogenesisGO:00488581230.221
Human
regulation of nervous system developmentGO:00519602640.215
Human
anatomical structure morphogenesisGO:00096532980.169
Human
regulation of secretionGO:00510462240.156
positive regulation of neurogenesisGO:00507691650.143
Human
positive regulation of cell differentiationGO:00455972170.141
Human
cellular component morphogenesisGO:00329891550.141
Human
axon cargo transportGO:000808810.140
protein complex biogenesisGO:00702712630.138
Human
neuron differentiationGO:00301823680.137
Human
positive regulation of neuron projection developmentGO:0010976990.133
Human
regulation of neuron projection developmentGO:00109751610.129
Human
regulation of cell differentiationGO:00455953200.127
Human
homeostatic processGO:00425923310.121
regulation of multicellular organismal developmentGO:20000263760.119
Human
macromolecular complex subunit organizationGO:00439333390.116
Human
response to woundingGO:00096112540.116
regulation of cellular component organizationGO:00511283680.114
Human
learning or memoryGO:0007611900.108
cellular component movementGO:00069282480.104
cellular component biogenesisGO:00440853680.104
Human
single organism intracellular transportGO:19025821660.103
cell projection organizationGO:00300303020.101
Human
regulation of neuron differentiationGO:00456642080.096
Human
growthGO:00400071650.096
Human
male mating behaviorGO:006017930.094
cellular component assemblyGO:00226073600.094
Human
inorganic cation transmembrane transportGO:00986622020.093
macromolecule localizationGO:00330362520.090
negative regulation of multicellular organismal processGO:00512412030.087
single organism catabolic processGO:00447122830.080
neuron projection morphogenesisGO:00488121220.080
Human
multicellular organismal signalingGO:0035637440.077
regulation of ion transportGO:00432692450.076
response to oxygen levelsGO:00704822650.075
regulation of neurogenesisGO:00507672470.073
Human
response to nutrient levelsGO:00316673700.071
neurological system processGO:00508772190.070
positive regulation of multicellular organismal processGO:00512403870.068
Human
response to inorganic substanceGO:00100353770.068
intracellular transportGO:00469071850.068
regulation of anatomical structure morphogenesisGO:00226031410.068
Human
cell cycleGO:00070491010.067
protein oligomerizationGO:00512591910.067
regulation of cell developmentGO:00602842630.067
Human
response to nutrientGO:00075842480.065
cell morphogenesis involved in differentiationGO:00009041190.064
Human
protein phosphorylationGO:00064683450.063
positive regulation of neuron differentiationGO:00456661260.062
Human
regulation of synapse maturationGO:009012820.061
negative regulation of neuron differentiationGO:0045665620.060
positive regulation of nervous system developmentGO:00519621780.059
Human
intracellular signal transductionGO:00355563140.058
response to radiationGO:00093141370.057
regulation of cell morphogenesisGO:0022604770.056
Human
protein complex assemblyGO:00064612630.056
Human
ribonucleotide catabolic processGO:00092611360.055
regulation of extent of cell growthGO:0061387250.055
Human
positive regulation of cell developmentGO:00107201760.054
Human
positive regulation of dendritic spine morphogenesisGO:006100330.054
central nervous system developmentGO:00074173110.054
organophosphate catabolic processGO:00464341480.053
protein localizationGO:00081041910.053
biological adhesionGO:00226101100.053
divalent metal ion transportGO:00708381320.051
metal ion transportGO:00300012890.051
reproductive processGO:00224143720.051
regulation of synaptic growth at neuromuscular junctionGO:000858210.049
response to carbohydrateGO:00097431830.049
regulation of cell cycleGO:0051726730.049
regulation of growthGO:00400081050.048
Human
synaptic growth at neuromuscular junctionGO:005112410.048
cognitionGO:0050890920.048
cellular protein localizationGO:00346131220.047
neuron developmentGO:00486662860.047
Human
regulation of cell morphogenesis involved in differentiationGO:0010769720.046
Human
positive regulation of synapse maturationGO:009012920.046
response to estradiolGO:00323551640.045
Rat
purine containing compound metabolic processGO:00725212530.045
positive regulation of cellular component organizationGO:00511302000.045
Human
heterocycle catabolic processGO:00467001670.044
cellular macromolecule localizationGO:00707271220.043
nucleotide metabolic processGO:00091172790.043
potassium ion transportGO:0006813970.043
macromolecular complex assemblyGO:00650032730.043
Human
positive regulation of biosynthetic processGO:00098913190.043
nucleoside triphosphate metabolic processGO:00091411440.041
cation transportGO:00068123820.041
cellular homeostasisGO:00197252520.041
single organism organelle organizationGO:19025891800.041
Human
calcium ion transportGO:00068161310.041
catabolic processGO:00090563510.041
Human
divalent inorganic cation transportGO:00725111340.041
intracellular protein transportGO:0006886790.041
positive regulation of cell communicationGO:00106472710.041
ion homeostasisGO:00508012120.040
gliogenesisGO:0042063930.039
aromatic compound catabolic processGO:00194391680.039
organonitrogen compound catabolic processGO:19015651790.039
regulation of developmental growthGO:0048638450.038
Human
developmental growth involved in morphogenesisGO:0060560330.037
Human
protein complex subunit organizationGO:00718223020.037
Human
secretion by cellGO:00329402480.037
regulation of rna biosynthetic processGO:20011413810.037
second messenger mediated signalingGO:0019932510.037
regulation of cell projection organizationGO:00313441750.037
Human
organic acid metabolic processGO:00060822920.037
cell migrationGO:00164771970.037
synaptic transmissionGO:00072682350.037
reproductionGO:00000032450.036
response to estrogenGO:00436272320.036
Rat
nucleoside phosphate metabolic processGO:00067532830.036
chemical homeostasisGO:00488782920.036
locomotionGO:00400112370.036
regulation of membrane potentialGO:00423911100.035
cell adhesionGO:00071551100.035
memoryGO:0007613540.035
axon ensheathmentGO:0008366400.035
regulation of nucleic acid templated transcriptionGO:19035063800.034
response to decreased oxygen levelsGO:00362932370.034
heart morphogenesisGO:000300730.033
cellular ketone metabolic processGO:0042180510.033
regulation of vesicle mediated transportGO:0060627810.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
regulation of intracellular signal transductionGO:19025312180.033
transmission of nerve impulseGO:0019226420.032
cellular response to oxygen containing compoundGO:19017013860.032
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.032
Human
response to metal ionGO:00100382530.032
vesicle mediated transportGO:00161921810.032
single organism reproductive processGO:00447022970.032
single organism biosynthetic processGO:00447113420.032
cellular amino acid metabolic processGO:00065201070.031
circulatory system developmentGO:00723591340.031
cell cell signalingGO:00072673350.031
cellular nitrogen compound catabolic processGO:00442701630.031
nucleoside triphosphate catabolic processGO:00091431230.031
programmed cell deathGO:00125013920.030
regulation of signal transductionGO:00099663180.030
regulation of dendrite developmentGO:0050773590.030
response to extracellular stimulusGO:00099913800.030
regulation of hormone secretionGO:00468831060.030
negative regulation of nervous system developmentGO:0051961790.030
regulation of secretion by cellGO:19035302080.029
insulin secretionGO:0030073690.029
multicellular organism reproductionGO:00325042330.029
neuron projection extensionGO:1990138260.029
Human
synapse organizationGO:0050808460.029
nucleoside phosphate catabolic processGO:19012921400.029
nucleotide catabolic processGO:00091661390.028
positive regulation of signal transductionGO:00099671750.028
response to temperature stimulusGO:0009266940.028
cation homeostasisGO:00550801950.027
negative regulation of developmental processGO:00510931250.027
secretionGO:00469033070.027
organophosphate metabolic processGO:00196373700.027
ensheathment of neuronsGO:0007272400.027
ribose phosphate metabolic processGO:00196932350.027
cellular catabolic processGO:00442482950.027
Human
transcription dna templatedGO:00063513770.027
purine ribonucleoside triphosphate metabolic processGO:00092051400.027
cell cell junction organizationGO:0045216200.026
wound healingGO:00420601220.026
multi organism reproductive processGO:00447032620.026
ribonucleoside catabolic processGO:00424541260.026
glycosyl compound metabolic processGO:19016571820.026
positive regulation of cell projection organizationGO:00313461110.026
Human
response to cytokineGO:00340972150.026
organic cyclic compound catabolic processGO:19013611750.026
glycosyl compound catabolic processGO:19016581260.025
agingGO:00075682410.025
negative regulation of cellular component organizationGO:0051129830.025
regulation of cellular ketone metabolic processGO:0010565270.025
response to hypoxiaGO:00016662310.025
negative regulation of response to stimulusGO:00485851550.025
divalent inorganic cation homeostasisGO:00725071650.025
response to monosaccharideGO:00342841590.025
regulation of synaptic transmissionGO:00508041410.025
ribonucleoside metabolic processGO:00091191740.025
multicellular organismal reproductive processGO:00486092330.025
carbohydrate metabolic processGO:00059751300.025
positive regulation of transportGO:00510502450.025
carbohydrate derivative metabolic processGO:19011353460.024
multicellular organismal homeostasisGO:0048871490.024
purine ribonucleoside catabolic processGO:00461301240.024
positive regulation of signalingGO:00230562700.024
purine nucleoside triphosphate metabolic processGO:00091441410.024
cellular chemical homeostasisGO:00550822470.024
regulation of cell motilityGO:20001451310.024
negative regulation of neurogenesisGO:0050768780.024
regulation of transcription dna templatedGO:00063553740.024
vesicle docking involved in exocytosisGO:000690440.024
negative regulation of cell developmentGO:0010721820.023
response to axon injuryGO:0048678590.023
regulation of body fluid levelsGO:0050878900.023
ribonucleoside triphosphate catabolic processGO:00092031220.023
protein homooligomerizationGO:0051260910.023
establishment of protein localizationGO:00451841410.023
cellular response to endogenous stimulusGO:00714953770.023
negative regulation of cell communicationGO:00106481580.023
renal system developmentGO:0072001670.023
behaviorGO:00076102050.023
organelle organizationGO:00069962660.023
Human
regulation of homeostatic processGO:00328441010.023
response to vitaminGO:00332731310.022
purine ribonucleotide catabolic processGO:00091541360.022
purine nucleotide catabolic processGO:00061951360.022
oxoacid metabolic processGO:00434362900.022
carboxylic acid metabolic processGO:00197522890.021
neuronal action potentialGO:0019228350.021
purine ribonucleotide metabolic processGO:00091502270.021
nucleobase containing small molecule metabolic processGO:00550863160.021
rna biosynthetic processGO:00327743800.021
cellular calcium ion homeostasisGO:00068741600.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
nuclear transportGO:0051169490.021
negative regulation of signalingGO:00230571570.021
amine metabolic processGO:0009308380.020
response to glucoseGO:00097491360.020
maintenance of locationGO:0051235170.020
vesicle localizationGO:0051648330.020
monovalent inorganic cation transportGO:00156721720.020
positive regulation of lipid catabolic processGO:005099640.020
response to light stimulusGO:0009416520.020
cell morphogenesisGO:00009021420.020
Human
synaptic vesicle endocytosisGO:004848840.020
regulation of synaptic plasticityGO:0048167700.020
cellular response to stressGO:00335542690.020
axonogenesisGO:0007409710.020
Human
carbohydrate derivative catabolic processGO:19011361470.019
spindle organizationGO:000705120.019
regulation of metal ion transportGO:00109591180.019
negative regulation of macromolecule metabolic processGO:00106052600.019
signal releaseGO:00230611450.019
regulation of cellular component biogenesisGO:0044087860.019
Human
adult locomotory behaviorGO:000834440.019
regulation of cellular amino acid metabolic processGO:000652120.019
negative regulation of cell differentiationGO:0045596990.019
regenerationGO:00310991630.019
purine nucleotide metabolic processGO:00061632290.019
positive regulation of response to stimulusGO:00485842850.019
developmental growthGO:00485891000.019
Human
regulation of dendritic spine morphogenesisGO:006100160.019
regulation of cellular localizationGO:00603412630.019
regulation of peptide hormone secretionGO:0090276800.019
regulation of locomotionGO:00400121480.019
nucleoside metabolic processGO:00091161790.019
negative regulation of transportGO:00510511360.018
regulation of apoptotic processGO:00429813350.018
regulation of cellular amine metabolic processGO:003323880.018
nucleobase containing compound catabolic processGO:00346551520.018
positive regulation of phosphate metabolic processGO:00459372620.018
cardiovascular system developmentGO:00723581340.018
purine nucleoside metabolic processGO:00422781690.018
cellular response to growth factor stimulusGO:00713631620.018
purine nucleoside triphosphate catabolic processGO:00091461220.018
cell cycle processGO:0022402570.018
sensory perceptionGO:00076001010.018
regulation of cell proliferationGO:00421273590.017
response to purine containing compoundGO:00140741260.017
response to acid chemicalGO:00011012220.017
axis specificationGO:000979840.017
nitrogen compound transportGO:00717052290.017
sequestering of metal ionGO:005123890.017
positive regulation of apoptotic processGO:00430651540.017
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.017
response to organophosphorusGO:00466831020.017
single organism carbohydrate metabolic processGO:00447231180.017
positive regulation of macromolecule biosynthetic processGO:00105572470.016
regulation of system processGO:00440572080.016
eye morphogenesisGO:004859240.016
cellular cation homeostasisGO:00300031800.016
regulation of phosphorus metabolic processGO:00511743490.016
developmental maturationGO:0021700250.016
regulation of axonogenesisGO:0050770370.016
Human
regulation of calcium ion transportGO:0051924770.016
nucleic acid templated transcriptionGO:00976593790.016
head developmentGO:00603222470.016
transcription from rna polymerase ii promoterGO:00063662520.016
olfactory learningGO:000835510.016
inorganic ion transmembrane transportGO:00986602290.016
ribonucleotide metabolic processGO:00092592310.016
regulation of phosphorylationGO:00423252480.015
locomotory exploration behaviorGO:003564110.015
regulation of rna metabolic processGO:00512523910.015
negative regulation of cell projection organizationGO:0031345500.015
reproductive system developmentGO:00614581280.015
regulation of insulin secretionGO:0050796650.015
morphogenesis of a polarized epitheliumGO:000173810.015
regulation of cell migrationGO:00303341280.015
response to hexoseGO:00097461440.015
g protein coupled receptor signaling pathwayGO:00071862420.015
response to other organismGO:00517072200.015
guanosine containing compound metabolic processGO:1901068740.015
monocarboxylic acid metabolic processGO:00327871520.015
negative regulation of signal transductionGO:0009968830.015
cellular amine metabolic processGO:0044106380.015
purine ribonucleoside metabolic processGO:00461281680.015
cellular macromolecular complex assemblyGO:0034622580.015
Human
cellular ion homeostasisGO:00068731840.014
rna metabolic processGO:00160704060.014
purine nucleoside catabolic processGO:00061521240.014
purine containing compound catabolic processGO:00725231380.014
small gtpase mediated signal transductionGO:0007264360.014
neuronal ion channel clusteringGO:004516130.014
axon extensionGO:0048675260.014
Human
response to oxidative stressGO:00069791860.014
peptide secretionGO:0002790860.014
multi multicellular organism processGO:00447061380.014
regulation of protein complex assemblyGO:0043254330.014
Human
cell cycle checkpointGO:000007520.014
regulation of cell growthGO:0001558850.014
Human
negative regulation of neuron projection developmentGO:0010977460.014
circulatory system processGO:00030131830.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
peptidyl amino acid modificationGO:00181931260.014
kidney developmentGO:0001822670.014
cellular response to lipidGO:00713962010.014
peptidyl tyrosine phosphorylationGO:0018108720.013
single organism behaviorGO:00447081300.013
cellular response to nitrogen compoundGO:19016992100.013
response to ketoneGO:19016541820.013
Rat
response to growth factorGO:00708481890.013
sexual reproductionGO:00199531480.013
immune system processGO:00023762040.013
reproductive structure developmentGO:00486081280.013
cellular protein complex assemblyGO:0043623440.013
Human
mapk cascadeGO:00001651400.013
positive regulation of gene expressionGO:00106282440.013
positive regulation of programmed cell deathGO:00430681570.013
cellular lipid metabolic processGO:00442552080.013
axon developmentGO:0061564960.013
Human
negative regulation of cellular metabolic processGO:00313242810.013
tissue developmentGO:00098882520.013
relaxation of muscleGO:009007540.013
glial cell differentiationGO:0010001650.013
cytoplasmic transportGO:00164821150.013
regulation of axon extensionGO:0030516240.013
Human
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
positive regulation of phosphorus metabolic processGO:00105622620.013
metal ion homeostasisGO:00550651860.013
mitotic spindle organizationGO:000705220.012
gamete generationGO:00072761240.012
macrophage chemotaxisGO:004824620.012
regulation of cellular protein metabolic processGO:00322682670.012
phototransduction visible lightGO:000760320.012
protein transportGO:00150311320.012
mitotic cell cycle processGO:1903047350.012
immune effector processGO:0002252530.012
rna localizationGO:000640340.012
peptidyl tyrosine modificationGO:0018212720.012
synapse assemblyGO:0007416290.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
transmembrane transportGO:00550854120.012
defense responseGO:00069521940.012
carbohydrate homeostasisGO:0033500750.012
centrosome organizationGO:005129710.012
regulation of blood vessel sizeGO:0050880890.012
cell motilityGO:00488702020.012
cell growthGO:00160491040.012
Human
cell junction organizationGO:0034330210.012
negative regulation of secretionGO:0051048820.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
gastrulationGO:000736920.011
organic hydroxy compound metabolic processGO:19016151150.011
response to activityGO:0014823730.011
action potentialGO:0001508540.011
small molecule biosynthetic processGO:00442831240.011
regulation of nucleotide catabolic processGO:0030811650.011
regulation of ion homeostasisGO:2000021630.011
regulation of protein modification processGO:00313991940.011
cellular component maintenanceGO:004395440.011
embryonic pattern specificationGO:000988010.011
regulation of dendrite morphogenesisGO:0048814330.011
negative regulation of protein phosphorylationGO:0001933440.011
leukocyte cell cell adhesionGO:000715940.011
urogenital system developmentGO:0001655780.011
anion transportGO:00068201780.011
cellular response to hormone stimulusGO:00328702470.011
positive regulation of potassium ion transmembrane transportGO:190138140.011
membrane organizationGO:0061024940.011
ion transmembrane transportGO:00342203650.011
protein localization to chromosome centromeric regionGO:007145910.011
olfactory behaviorGO:004204820.011
positive regulation of dendrite morphogenesisGO:0050775210.011
calcium ion homeostasisGO:00550741620.011
ras protein signal transductionGO:0007265290.011
regulation of ovulationGO:006027820.011
response to molecule of bacterial originGO:00022371940.011
sensory perception of bitter tasteGO:005091340.011
male gamete generationGO:0048232990.011
cardiac conductionGO:006133720.011
regulation of cellular catabolic processGO:00313291010.011
Human
cellular response to glucose stimulusGO:0071333650.010
positive regulation of protein modification processGO:00314011420.010
positive regulation of transcription dna templatedGO:00458931970.010
circadian rhythmGO:0007623880.010
regulation of gtpase activityGO:0043087570.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.010
cellular response to organonitrogen compoundGO:00714171970.010
positive regulation of ion transportGO:0043270940.010
anterior posterior pattern specificationGO:000995210.010
hormone secretionGO:00468791150.010
regulation of anatomical structure sizeGO:00900661350.010
Human
positive regulation of protein metabolic processGO:00512471780.010
regulation of cell maturationGO:190342930.010
centrosome cycleGO:000709810.010
cell cycle g1 s phase transitionGO:0044843130.010
response to corticosteroidGO:00319602350.010
positive regulation of rna biosynthetic processGO:19026801970.010
positive regulation of rna metabolic processGO:00512542030.010

Mapt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.067
Human
disease of anatomical entityDOID:700.067
Human
brain diseaseDOID:93600.036
Human
central nervous system diseaseDOID:33100.036
Human
disease of metabolismDOID:001466700.021
inherited metabolic disorderDOID:65500.021
carbohydrate metabolic disorderDOID:297800.020
long qt syndromeDOID:284300.017
epilepsy syndromeDOID:182600.016
electroclinical syndromeDOID:005070100.011
neonatal period electroclinical syndromeDOID:005070200.011
ohtahara syndromeDOID:005070900.011